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Search of human proteins with 4758440
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758440 glia maturation factor, gamma [Homo sapiens]
(142 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758440 glia maturation factor, gamma [Homo sapiens] 287 2e-78
gi|4758442 glia maturation factor, beta [Homo sapiens] 244 2e-65
gi|40068475 twinfilin 1 [Homo sapiens] 43 8e-05
gi|6005846 twinfilin-like protein [Homo sapiens] 41 4e-04
gi|5031635 cofilin 1 (non-muscle) [Homo sapiens] 31 0.39
gi|14719392 cofilin 2 [Homo sapiens] 30 0.88
gi|33946278 cofilin 2 [Homo sapiens] 30 0.88
gi|239735605 leucine rich repeat containing 36 isoform 1 [Homo s... 28 2.0
gi|5902052 relaxin 1 preproprotein [Homo sapiens] 28 2.0
gi|239735598 leucine rich repeat containing 36 isoform 2 [Homo s... 28 2.0
gi|20986490 YY1-associated protein isoform 3 [Homo sapiens] 28 2.0
gi|82830424 gon-4-like isoform a [Homo sapiens] 28 2.0
gi|82830428 gon-4-like isoform b [Homo sapiens] 28 2.0
gi|20143933 relaxin 2 isoform 1 preproprotein [Homo sapiens] 28 3.3
gi|45505178 cancer antigen 1 [Homo sapiens] 27 4.4
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 27 4.4
gi|149773468 RAD51 associated protein 2 [Homo sapiens] 27 4.4
gi|124517699 ankyrin repeat domain 13B [Homo sapiens] 27 5.7
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 27 7.4
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 27 7.4
gi|15826862 coiled-coil domain containing 120 isoform 3 [Homo sa... 26 9.7
gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo s... 26 9.7
gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo s... 26 9.7
gi|254039610 coiled-coil domain containing 120 isoform 1 [Homo s... 26 9.7
gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo s... 26 9.7
gi|81295809 pericentrin [Homo sapiens] 26 9.7
>gi|4758440 glia maturation factor, gamma [Homo sapiens]
Length = 142
Score = 287 bits (735), Expect = 2e-78
Identities = 142/142 (100%), Positives = 142/142 (100%)
Query: 1 MSDSLVVCEVDPELTEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKME 60
MSDSLVVCEVDPELTEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKME
Sbjct: 1 MSDSLVVCEVDPELTEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKME 60
Query: 61 LPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKV 120
LPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKV
Sbjct: 61 LPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKV 120
Query: 121 FEIRTTDDLTEAWLQEKLSFFR 142
FEIRTTDDLTEAWLQEKLSFFR
Sbjct: 121 FEIRTTDDLTEAWLQEKLSFFR 142
>gi|4758442 glia maturation factor, beta [Homo sapiens]
Length = 142
Score = 244 bits (622), Expect = 2e-65
Identities = 116/141 (82%), Positives = 131/141 (92%)
Query: 1 MSDSLVVCEVDPELTEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKME 60
MS+SLVVC+V +L EKLRKFRFRKET+NAAIIMK+DKD+++VVL+EE + ISP+ELK E
Sbjct: 1 MSESLVVCDVAEDLVEKLRKFRFRKETNNAAIIMKIDKDKRLVVLDEELEGISPDELKDE 60
Query: 61 LPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKV 120
LPERQPRF+VYSYKY HDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKN+LVQTAELTKV
Sbjct: 61 LPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKV 120
Query: 121 FEIRTTDDLTEAWLQEKLSFF 141
FEIR T+DLTE WL+EKL FF
Sbjct: 121 FEIRNTEDLTEEWLREKLGFF 141
>gi|40068475 twinfilin 1 [Homo sapiens]
Length = 384
Score = 43.1 bits (100), Expect = 8e-05
Identities = 28/112 (25%), Positives = 58/112 (51%), Gaps = 9/112 (8%)
Query: 34 MKVDKDRQMVVLEEEFQNISPEELKMELPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSP 93
+++D ++++L N ++L +P+ R+ + YK+ H+ G + FI+S P
Sbjct: 237 LEIDIKNEIIILANT-TNTELKDLPKRIPKDSARYHFFLYKHSHE-GDYLESIVFIYSMP 294
Query: 94 -VGCKPEQQMMYAGSKNRLVQTAE------LTKVFEIRTTDDLTEAWLQEKL 138
C ++M+Y+ K+RL++ E + + EI D+LT +L E++
Sbjct: 295 GYTCSIRERMLYSSCKSRLLEIVERQLQMDVIRKIEIDNGDELTADFLYEEV 346
>gi|6005846 twinfilin-like protein [Homo sapiens]
Length = 349
Score = 40.8 bits (94), Expect = 4e-04
Identities = 33/118 (27%), Positives = 61/118 (51%), Gaps = 17/118 (14%)
Query: 32 IIMKVDKDRQMVVLEEEFQNISPEELKMELPERQPR----FVVYSYKYVHDDGRVSYPLC 87
I MK+D +R+ + E + P ++ +LP R PR + + YK+ H+ G +
Sbjct: 201 IQMKLDLERETI----ELVHTEPTDVA-QLPSRVPRDAARYHFFLYKHTHE-GDPLESVV 254
Query: 88 FIFSSP-VGCKPEQQMMYAGSKNRLVQTA------ELTKVFEIRTTDDLTEAWLQEKL 138
FI+S P C +++M+Y+ K+RL+ + E+ K EI +LT +L +++
Sbjct: 255 FIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKIEIGDGAELTAEFLYDEV 312
>gi|5031635 cofilin 1 (non-muscle) [Homo sapiens]
Length = 166
Score = 30.8 bits (68), Expect = 0.39
Identities = 22/92 (23%), Positives = 46/92 (50%), Gaps = 13/92 (14%)
Query: 31 AIIMKVDKDRQMVVLEEEFQNISPEE-----------LKMELPERQPRFVVYSYKYVHDD 79
A++ + +D++ ++LEE + + + +KM LP++ R+ +Y Y +
Sbjct: 35 AVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKM-LPDKDCRYALYDATYETKE 93
Query: 80 GRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRL 111
+ L FIF +P + +M+YA SK+ +
Sbjct: 94 SKKE-DLVFIFWAPESAPLKSKMIYASSKDAI 124
>gi|14719392 cofilin 2 [Homo sapiens]
Length = 166
Score = 29.6 bits (65), Expect = 0.88
Identities = 30/136 (22%), Positives = 61/136 (44%), Gaps = 15/136 (11%)
Query: 17 KLRKFRFRKETDNA--AIIMKVDKDRQMVVLEEEFQNISPE----------ELKMELPER 64
K+RK ++E A++ + D++ +++EE Q + + LP
Sbjct: 19 KVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSFVKLLPLN 78
Query: 65 QPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQT-AELTKVFEI 123
R+ +Y Y + + L FIF +P + +M+YA SK+ + + + +++
Sbjct: 79 DCRYALYDATYETKESKKE-DLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQV 137
Query: 124 RTTDDLTE-AWLQEKL 138
DD+ + + L EKL
Sbjct: 138 NGLDDIKDRSTLGEKL 153
>gi|33946278 cofilin 2 [Homo sapiens]
Length = 166
Score = 29.6 bits (65), Expect = 0.88
Identities = 30/136 (22%), Positives = 61/136 (44%), Gaps = 15/136 (11%)
Query: 17 KLRKFRFRKETDNA--AIIMKVDKDRQMVVLEEEFQNISPE----------ELKMELPER 64
K+RK ++E A++ + D++ +++EE Q + + LP
Sbjct: 19 KVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSFVKLLPLN 78
Query: 65 QPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQT-AELTKVFEI 123
R+ +Y Y + + L FIF +P + +M+YA SK+ + + + +++
Sbjct: 79 DCRYALYDATYETKESKKE-DLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQV 137
Query: 124 RTTDDLTE-AWLQEKL 138
DD+ + + L EKL
Sbjct: 138 NGLDDIKDRSTLGEKL 153
>gi|239735605 leucine rich repeat containing 36 isoform 1 [Homo
sapiens]
Length = 754
Score = 28.5 bits (62), Expect = 2.0
Identities = 17/78 (21%), Positives = 33/78 (42%), Gaps = 14/78 (17%)
Query: 46 EEEFQNISPEELKMELPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCKPEQQMMYA 105
E+EF++ SP + + PE+ R Y + F+ + G PE++++
Sbjct: 250 EDEFRHYSPRQSTVRSPEKMT--------------REGYQVSFLDNKSSGSSPEKELIPK 295
Query: 106 GSKNRLVQTAELTKVFEI 123
L A L+K ++
Sbjct: 296 PDTFHLTHDASLSKCLDV 313
>gi|5902052 relaxin 1 preproprotein [Homo sapiens]
Length = 185
Score = 28.5 bits (62), Expect = 2.0
Identities = 13/31 (41%), Positives = 19/31 (61%)
Query: 36 VDKDRQMVVLEEEFQNISPEELKMELPERQP 66
++KD + +++ EF P ELK L ERQP
Sbjct: 77 INKDTETIIIMLEFIANLPPELKAALSERQP 107
>gi|239735598 leucine rich repeat containing 36 isoform 2 [Homo
sapiens]
Length = 633
Score = 28.5 bits (62), Expect = 2.0
Identities = 17/78 (21%), Positives = 33/78 (42%), Gaps = 14/78 (17%)
Query: 46 EEEFQNISPEELKMELPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCKPEQQMMYA 105
E+EF++ SP + + PE+ R Y + F+ + G PE++++
Sbjct: 129 EDEFRHYSPRQSTVRSPEKMT--------------REGYQVSFLDNKSSGSSPEKELIPK 174
Query: 106 GSKNRLVQTAELTKVFEI 123
L A L+K ++
Sbjct: 175 PDTFHLTHDASLSKCLDV 192
>gi|20986490 YY1-associated protein isoform 3 [Homo sapiens]
Length = 750
Score = 28.5 bits (62), Expect = 2.0
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 1 MSDSLVVCEVDPELTEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKME 60
+S L+ C+ +LT +++ + DN II K +Q+ VL + + I P + K
Sbjct: 262 ISKYLLTCKTARQLTVRIKNLNMNRAPDN--IIKFYKKTKQLPVLGKCCEEIQPHQWKPP 319
Query: 61 LPERQPR 67
+ + R
Sbjct: 320 IEREEHR 326
>gi|82830424 gon-4-like isoform a [Homo sapiens]
Length = 2240
Score = 28.5 bits (62), Expect = 2.0
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 1 MSDSLVVCEVDPELTEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKME 60
+S L+ C+ +LT +++ + DN II K +Q+ VL + + I P + K
Sbjct: 851 ISKYLLTCKTAHQLTVRIKNLNMNRAPDN--IIKFYKKTKQLPVLGKCCEEIQPHQWKPP 908
Query: 61 LPERQPR 67
+ + R
Sbjct: 909 IEREEHR 915
>gi|82830428 gon-4-like isoform b [Homo sapiens]
Length = 1529
Score = 28.5 bits (62), Expect = 2.0
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 1 MSDSLVVCEVDPELTEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKME 60
+S L+ C+ +LT +++ + DN II K +Q+ VL + + I P + K
Sbjct: 851 ISKYLLTCKTAHQLTVRIKNLNMNRAPDN--IIKFYKKTKQLPVLGKCCEEIQPHQWKPP 908
Query: 61 LPERQPR 67
+ + R
Sbjct: 909 IEREEHR 915
>gi|20143933 relaxin 2 isoform 1 preproprotein [Homo sapiens]
Length = 185
Score = 27.7 bits (60), Expect = 3.3
Identities = 12/31 (38%), Positives = 19/31 (61%)
Query: 36 VDKDRQMVVLEEEFQNISPEELKMELPERQP 66
++KD + + + EF P+ELK+ L E QP
Sbjct: 77 INKDTETINMMSEFVANLPQELKLTLSEMQP 107
>gi|45505178 cancer antigen 1 [Homo sapiens]
Length = 641
Score = 27.3 bits (59), Expect = 4.4
Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 1 MSDSLVVCEVDPELTEKLRKFRFRKETDNAAIIMKVDKDRQ---MVVLEEEFQNISPEEL 57
M +L E + E ++L+K K T +A ++K +K+ Q + L+EEFQ + E L
Sbjct: 305 MDKTLSKKEEEVERLQQLKK-ELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENL 363
Query: 58 K 58
+
Sbjct: 364 E 364
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 27.3 bits (59), Expect = 4.4
Identities = 14/46 (30%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Query: 9 EVDPELTEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISP 54
+++ E+ EK+ R KE +NA ++ K + ++ EEE +SP
Sbjct: 337 QMEKEMLEKIG--RLEKELENANDLLSATKRKGAILSEEELAAMSP 380
>gi|149773468 RAD51 associated protein 2 [Homo sapiens]
Length = 1159
Score = 27.3 bits (59), Expect = 4.4
Identities = 14/48 (29%), Positives = 20/48 (41%)
Query: 38 KDRQMVVLEEEFQNISPEELKMELPERQPRFVVYSYKYVHDDGRVSYP 85
K +V + NIS LK+ + QP + Y D G +S P
Sbjct: 213 KANSVVPSNKRENNISSSVLKISKSQNQPSLEIAKPSYFRDSGTISVP 260
>gi|124517699 ankyrin repeat domain 13B [Homo sapiens]
Length = 626
Score = 26.9 bits (58), Expect = 5.7
Identities = 12/28 (42%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Query: 19 RKFRFRKETDNAAIIMKVDKDRQMVVLE 46
R F FR + D +A++M++D DR++V E
Sbjct: 181 RSFVFRGQ-DTSAVVMEIDHDRRVVYTE 207
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 26.6 bits (57), Expect = 7.4
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 66 PRFVVYSYKYVHDDGRVSYPLCFIFSSP---VGCKPEQQMMYAGSKNRLVQTAELTKV 120
PRF+ +V G+ + C I +P V + +QQ + AG++ RL Q +L ++
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRL 67
>gi|148833506 obscurin, cytoskeletal calmodulin and
titin-interacting RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 26.6 bits (57), Expect = 7.4
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 66 PRFVVYSYKYVHDDGRVSYPLCFIFSSP---VGCKPEQQMMYAGSKNRLVQTAELTKV 120
PRF+ +V G+ + C I +P V + +QQ + AG++ RL Q +L ++
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRL 67
>gi|15826862 coiled-coil domain containing 120 isoform 3 [Homo
sapiens]
Length = 630
Score = 26.2 bits (56), Expect = 9.7
Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
Query: 9 EVDPEL-TEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKMELPERQPR 67
E P++ +E+LR R+ T A+ +K+ + R++ + E E P E +E P +P+
Sbjct: 22 EAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLE-PGERPQ 80
Query: 68 FV 69
V
Sbjct: 81 LV 82
>gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo
sapiens]
Length = 618
Score = 26.2 bits (56), Expect = 9.7
Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
Query: 9 EVDPEL-TEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKMELPERQPR 67
E P++ +E+LR R+ T A+ +K+ + R++ + E E P E +E P +P+
Sbjct: 10 EAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLE-PGERPQ 68
Query: 68 FV 69
V
Sbjct: 69 LV 70
>gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo
sapiens]
Length = 649
Score = 26.2 bits (56), Expect = 9.7
Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
Query: 9 EVDPEL-TEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKMELPERQPR 67
E P++ +E+LR R+ T A+ +K+ + R++ + E E P E +E P +P+
Sbjct: 10 EAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLE-PGERPQ 68
Query: 68 FV 69
V
Sbjct: 69 LV 70
>gi|254039610 coiled-coil domain containing 120 isoform 1 [Homo
sapiens]
Length = 661
Score = 26.2 bits (56), Expect = 9.7
Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
Query: 9 EVDPEL-TEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKMELPERQPR 67
E P++ +E+LR R+ T A+ +K+ + R++ + E E P E +E P +P+
Sbjct: 22 EAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLE-PGERPQ 80
Query: 68 FV 69
V
Sbjct: 81 LV 82
>gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo
sapiens]
Length = 1133
Score = 26.2 bits (56), Expect = 9.7
Identities = 11/21 (52%), Positives = 15/21 (71%)
Query: 42 MVVLEEEFQNISPEELKMELP 62
M VL EEF N++PE+L +P
Sbjct: 1 MDVLAEEFGNLTPEQLAAPIP 21
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 26.2 bits (56), Expect = 9.7
Identities = 15/55 (27%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Query: 10 VDPELTEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKMELPER 64
+D E+ +K R + + N I K DRQ+++ EEE + + EE+ + + ++
Sbjct: 1525 LDGEVELLQQKLREKLDEFNELAIQKESADRQVLMQEEEIKRL--EEMNINIRKK 1577
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,227,791
Number of Sequences: 37866
Number of extensions: 215539
Number of successful extensions: 555
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 547
Number of HSP's gapped (non-prelim): 28
length of query: 142
length of database: 18,247,518
effective HSP length: 92
effective length of query: 50
effective length of database: 14,763,846
effective search space: 738192300
effective search space used: 738192300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.