Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 46852390
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46852390 coiled-coil domain containing 6 [Homo sapiens]
(474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46852390 coiled-coil domain containing 6 [Homo sapiens] 940 0.0
gi|21735548 centrosomal protein 2 [Homo sapiens] 77 4e-14
gi|56549694 enabled homolog isoform a [Homo sapiens] 74 3e-13
gi|39930375 enabled homolog isoform b [Homo sapiens] 74 3e-13
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 74 4e-13
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 74 4e-13
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 73 5e-13
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 73 5e-13
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 73 5e-13
gi|122937271 WAS protein homolog associated with actin, golgi me... 73 6e-13
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 72 8e-13
gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens] 72 8e-13
gi|148746195 trichohyalin [Homo sapiens] 71 2e-12
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 70 5e-12
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 69 7e-12
gi|7662302 TBK1 binding protein 1 [Homo sapiens] 69 9e-12
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 69 1e-11
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 69 1e-11
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 69 1e-11
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 68 2e-11
gi|187761324 shootin1 isoform a [Homo sapiens] 67 3e-11
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 67 4e-11
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 67 5e-11
gi|119395750 keratin 1 [Homo sapiens] 66 6e-11
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 66 6e-11
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 66 8e-11
gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-l... 65 1e-10
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l... 65 1e-10
gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-l... 65 1e-10
gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-l... 65 1e-10
>gi|46852390 coiled-coil domain containing 6 [Homo sapiens]
Length = 474
Score = 940 bits (2430), Expect = 0.0
Identities = 474/474 (100%), Positives = 474/474 (100%)
Query: 1 MADSASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELT 60
MADSASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELT
Sbjct: 1 MADSASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELT 60
Query: 61 NRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKI 120
NRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKI
Sbjct: 61 NRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKI 120
Query: 121 QALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKK 180
QALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKK
Sbjct: 121 QALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKK 180
Query: 181 LENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVS 240
LENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVS
Sbjct: 181 LENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVS 240
Query: 241 APPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREE 300
APPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREE
Sbjct: 241 APPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREE 300
Query: 301 NLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSP 360
NLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSP
Sbjct: 301 NLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSP 360
Query: 361 SSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSP 420
SSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSP
Sbjct: 361 SSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSP 420
Query: 421 DKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTPSQHSAHPSSQP 474
DKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTPSQHSAHPSSQP
Sbjct: 421 DKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTPSQHSAHPSSQP 474
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 76.6 bits (187), Expect = 4e-14
Identities = 81/307 (26%), Positives = 147/307 (47%), Gaps = 39/307 (12%)
Query: 57 EELTNRLASLQQENKV-------LKIELETYKLKCKALQEENRDLRKASVTIQARAEQEE 109
E L + L QQ+N V L+++++T + +Q E R L+ T +++AEQE
Sbjct: 767 ELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQER 826
Query: 110 EFISNTLFKKIQ-----------ALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAE 158
+ + L + Q A +KE L +EKE + EL++ L L+ EK E
Sbjct: 827 DAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKME 886
Query: 159 LEQHL-EQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVN-- 215
LE L EQ+ E + + ++ ++ + ++ Q+ LE +E++ L TL Q Q+ L +
Sbjct: 887 LEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLE-TEKERVSLLETLLQTQKELADAS 945
Query: 216 ------RLWKRMDKLEAEKR--ILQEKLDQ-----PVSAPPSPRDISMEIDSPENMMRHI 262
R ++ KL+ ++ ILQ +L + +A D++ + ++++
Sbjct: 946 QQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDK 1005
Query: 263 RFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQL 322
L+ +VE LK QL AQ + Q ++E+ +E R+Q++L+RE + +L L
Sbjct: 1006 MDLQKQVEDLKSQL-VAQDDSQRLVEQEVQEKLRETQEYNRIQKELERE---KASLTLSL 1061
Query: 323 SESESSL 329
E E L
Sbjct: 1062 MEKEQRL 1068
Score = 58.2 bits (139), Expect = 2e-08
Identities = 72/346 (20%), Positives = 144/346 (41%), Gaps = 66/346 (19%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCK-------------------ALQEENRDLR 95
+++ +T +Q E + LK+EL+T + + + AL+++
Sbjct: 793 QIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHE 852
Query: 96 KASVTIQARAEQEEEFISNTLFKKIQALQKEK------------ETLAVNYEKEEEFLTN 143
K ++ + E+E + L K +++L++EK E A+ ++EEE
Sbjct: 853 KEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA 912
Query: 144 E----------------LSRKLMQLQHEKAELEQHLEQ-EQEFQVNKLMKKIKK--LEND 184
E L L+Q Q E A+ Q LE+ Q+ +V KL ++ L+
Sbjct: 913 ESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQ 972
Query: 185 TISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPS 244
Q L++ R+ D L++E +L+ DK++ +K++ ++ Q V+ S
Sbjct: 973 LQEAQRELKEAARQHRDDLAALQEESSSLL------QDKMDLQKQV-EDLKSQLVAQDDS 1025
Query: 245 PRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRL 304
R + E+ + ++ E+ER K L L E+ L+E +R++ L
Sbjct: 1026 QRLVEQEVQEKLRETQEYNRIQKELEREKASL-TLSLMEKEQRLLVLQEADSIRQQELSA 1084
Query: 305 QRKLQREME--------RREALCRQLSESESSLEMDDERYFNEMSA 342
R+ +E + + E L +++ E E+ + + E+ A
Sbjct: 1085 LRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEA 1130
Score = 53.1 bits (126), Expect = 5e-07
Identities = 68/312 (21%), Positives = 141/312 (45%), Gaps = 57/312 (18%)
Query: 57 EELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKA---------SVTIQARAEQ 107
E+L ++L+ +N+ E+E+ + + +ALQE+ +L+ A ++ Q AE+
Sbjct: 1379 EDLRTARSALKLKNE----EVESERERAQALQEQG-ELKVAQGKALQENLALLTQTLAER 1433
Query: 108 EEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQ 167
EEE TL +IQ L+K++E + + +L+ L +K E L+QEQ
Sbjct: 1434 EEEV--ETLRGQIQELEKQREM-------------QKAALELLSLDLKKRNQEVDLQQEQ 1478
Query: 168 EFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLW---KRMDKL 224
++ K ++ L ++ L R + +LE E ++ L ++L K+ +
Sbjct: 1479 IQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMI 1538
Query: 225 EAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKK---------- 274
E+++ +Q+ Q V+ +++E++ + M + L E+E ++
Sbjct: 1539 ESQRGQVQDLKKQLVTL----ECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLT 1594
Query: 275 ----------QLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMER-REALCRQLS 323
Q +++Q+ E + L E R++ ++ QR+ E++R +E L + L
Sbjct: 1595 LDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLE 1654
Query: 324 ESESSLEMDDER 335
+ L + ER
Sbjct: 1655 RRDQELMLQKER 1666
Score = 52.8 bits (125), Expect = 7e-07
Identities = 70/300 (23%), Positives = 129/300 (43%), Gaps = 29/300 (9%)
Query: 63 LASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQA 122
+A L LK E+ + L N L V + + Q EE + ++ +++A
Sbjct: 577 IAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEE-NQSVCSRMEA 635
Query: 123 LQKEKETLAVNY---EKEEEFL---TNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMK 176
++ + L V+ EK E L L +L + + AEL+ L QE + ++ K
Sbjct: 636 AEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQE-EKEEIQK 694
Query: 177 KIKKLENDTISKQLTLEQLRREKIDLENTLE---QEQEALVNR---LWKRMDKLEAEKRI 230
K+ + + + LEQL +E E L QE+EALV L R+ +E +++
Sbjct: 695 KLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQD 754
Query: 231 LQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQY 290
L E+L + +S + E+ + + + +E K QL Q+Q + +
Sbjct: 755 LAEQL----------QGLSSAKELLESSLFEAQQQNSVIEVTKGQLE-VQIQTVTQAKEV 803
Query: 291 LEEERHMREENLRLQRKLQREMERREALCRQL--SESESSLEMDDERYFNEMSAQGLRPR 348
++ E +R L L + + + R+A RQL +E E ++ ++ +E LR +
Sbjct: 804 IQGE--VRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREK 861
Score = 51.2 bits (121), Expect = 2e-06
Identities = 58/288 (20%), Positives = 130/288 (45%), Gaps = 29/288 (10%)
Query: 58 ELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQAR---AEQEEEFISN 114
+L + SL +E ++L+ E + + + L++E LR+ +V +Q + A+ ++E
Sbjct: 453 DLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQE 512
Query: 115 TLFKKIQALQKEKETLAVNYEKEEEFLTNELS-RKLMQLQHEKAELEQHLEQEQEFQVNK 173
L ++ ++ +E L K+ E L+ ++ R+ ++ H + EL + + E + +
Sbjct: 513 ELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALAR 572
Query: 174 LMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQE 233
+ I +L + + + + LR + L EAL +DK+ +++LQ
Sbjct: 573 AEQSIAELSSSENTLKTEVADLRAAAVKLSAL----NEALA------LDKVGLNQQLLQL 622
Query: 234 KLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQL------RAAQLQHSEKM 287
+ + + + +++ E ++ E E+ ++ L AQLQ +E+
Sbjct: 623 EEEN--------QSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEA 674
Query: 288 AQYLEEE-RHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDE 334
L+ + R ++EE +Q+KL ++EA QL + + +E
Sbjct: 675 GAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEE 722
Score = 50.1 bits (118), Expect = 4e-06
Identities = 66/291 (22%), Positives = 133/291 (45%), Gaps = 47/291 (16%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNT 115
LEE +++ Q+ K L+ + ET ++ AL DL + S +QA++ Q + S++
Sbjct: 1562 LEENHHKMECQQKLIKELEGQRETQRV---ALTHLTLDLEERSQELQAQSSQIHDLESHS 1618
Query: 116 LFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQ-EQEFQVNKL 174
+ ++++E + + EE LQ +K L Q LE+ +QE + K
Sbjct: 1619 TVLARELQERDQEVKSQREQIEE-------------LQRQKEHLTQDLERRDQELMLQK- 1664
Query: 175 MKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEK 234
++I+ LE+ ++ R+ KI LE++ E + L +R +L +++++QE+
Sbjct: 1665 -ERIQVLED---------QRTRQTKI-----LEEDLEQIKLSLRERGRELTTQRQLMQER 1709
Query: 235 LDQ---PVSAPPSP--------RDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQH 283
++ P A RD E+ E HI L+ ++L++QL+ +
Sbjct: 1710 AEEGKGPSKAQRGSLEHMKLILRDKEKEV---ECQQEHIHELQELKDQLEQQLQGLHRKV 1766
Query: 284 SEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDE 334
E + E+ + +LQ ++ + ++L QL E++ +L D+
Sbjct: 1767 GETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQ 1817
Score = 48.9 bits (115), Expect = 1e-05
Identities = 71/284 (25%), Positives = 124/284 (43%), Gaps = 39/284 (13%)
Query: 59 LTNRLASLQQENKVLKIELETYKLKCKA-LQEENRDLRKASVTIQARAEQEE------EF 111
L + A QE++V L+ L+ +A L+E +++L Q+ QEE E
Sbjct: 1906 LQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEA 1965
Query: 112 ISNTLFKKIQALQKEKETLAVNYE--KEEEFLTNELSRKLMQLQHEKAELEQHLE-QEQE 168
+ L K ALQ +++ L E + E T L L Q +LE+ L QE E
Sbjct: 1966 LQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGE 2025
Query: 169 FQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQ---EALVNRLWKRMDKLE 225
Q L + + D Q L Q E L + E+EQ ++L R+ + M ++
Sbjct: 2026 IQDQDL-----RYQEDVQQLQQALAQRDEE---LRHQQEREQLLEKSLAQRVQENM--IQ 2075
Query: 226 AEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSE 285
++ + QE+ ++ EI +R ++ + E+ +LR Q +++
Sbjct: 2076 EKQNLGQEREEE-------------EIRGLHQSVRELQLTLAQKEQEILELRETQQRNNL 2122
Query: 286 KMAQYLEEERHMREENLRL---QRKLQREMERREALCRQLSESE 326
+ + + M E++L+L + +LQRE+ER +A RQ E
Sbjct: 2123 EALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEARE 2166
Score = 40.0 bits (92), Expect = 0.005
Identities = 74/304 (24%), Positives = 131/304 (43%), Gaps = 57/304 (18%)
Query: 55 RLEELTNRLASLQQENKVLKIEL----ETYKLKCKALQEENRDLRKASVTIQARAEQEEE 110
++ E + L+ +QE VL+ +L E +LK ++LQ + + ++A A++++E
Sbjct: 1765 KVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRAL------AQRDQE 1818
Query: 111 FISNTLFKKIQALQKEKETLAVNYEKEEE---FLTNELSRKLMQLQHEKAELEQHLEQ-- 165
++ALQ+E++ E+ +E L L + M L+ EL+ H EQ
Sbjct: 1819 ---------LEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQAR 1869
Query: 166 --EQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDK 223
E+E V ++++ LE L LR E + E L AL + ++ +
Sbjct: 1870 RLEEELAVEG--RRVQALEE-------VLGDLRAESREQEKAL----LALQQQCAEQAQE 1916
Query: 224 LEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQH 283
E E R LQ+ Q A RD +E E+ +++ E + + A Q
Sbjct: 1917 HEVETRALQDSWLQ-AQAVLKERDQELEALRAESQSS-----RHQEEAARARAEALQEAL 1970
Query: 284 SEKMAQYLEEERHMREENLRLQRK-------LQREMERREALCRQLSES----ESSLEMD 332
+ A +E+H+ E+ L R LQ ++ +A RQL E+ E ++
Sbjct: 1971 GKAHAALQGKEQHLLEQ-AELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQ 2029
Query: 333 DERY 336
D RY
Sbjct: 2030 DLRY 2033
Score = 39.7 bits (91), Expect = 0.006
Identities = 62/281 (22%), Positives = 115/281 (40%), Gaps = 28/281 (9%)
Query: 73 LKIELETYKLKCKALQEENRDLR----KASVTIQARAEQEEEFISNTLFKKIQALQKEKE 128
L + LE + +C++L E N LR KA V +A E E+ + + + ++KE +
Sbjct: 99 LLVRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQ 158
Query: 129 TLAVNYEKEEEFLTNELSR---KLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDT 185
++ E+EF L +L+ L E +H + + LM+ K E+
Sbjct: 159 -----WQMEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEMKSATDRDLMEL--KAEHVR 211
Query: 186 ISKQLTLEQLR------REKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPV 239
+S L LR + + ++ + A + L + +LE E ++L Q
Sbjct: 212 LSGSLLTCCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQELIQLK 271
Query: 240 SAPPSPR-DISMEIDSPENMMRHIRFLKNEVERLKKQLRAA----QLQHSEKMAQYLEEE 294
S + ++ + ++ + + E++ K LR + H+E M
Sbjct: 272 SQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLS 331
Query: 295 RHMREENLRLQ---RKLQREMERREALCRQLSESESSLEMD 332
R+ +EE L LQ + + + M Q S E+SLE+D
Sbjct: 332 RNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELD 372
Score = 36.2 bits (82), Expect = 0.067
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 8/167 (4%)
Query: 158 ELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRL 217
+L Q L + Q+ + + L +++KLE + Q+ E DL+ L Q QE
Sbjct: 1247 KLHQDLWKTQQTR-DVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEE--KSK 1303
Query: 218 WK-RMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIR-FLKNEVERLKKQ 275
W+ + + LE+E L E + S ME +++ + L +VE L+
Sbjct: 1304 WEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAA 1363
Query: 276 LRAAQLQHSEKMAQYLEEERHMREENLRLQ-RKLQREMERREALCRQ 321
+ A+ Q S A LEE+ L+L+ +++ E ER +AL Q
Sbjct: 1364 VVEARAQAS--AAGILEEDLRTARSALKLKNEEVESERERAQALQEQ 1408
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 73.9 bits (180), Expect = 3e-13
Identities = 89/337 (26%), Positives = 141/337 (41%), Gaps = 82/337 (24%)
Query: 132 VNYEKEEEFLTNELSRKLMQLQH--EKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQ 189
+N ++ L + S+ Q+Q+ + ELE Q QE Q K +++ ++LE + + ++
Sbjct: 111 LNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELER-ERLERERMERE 169
Query: 190 -LTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDI 248
L E+L RE+++ E LEQEQ + +R ++LE ++R+ ++
Sbjct: 170 RLERERLERERLERER-LEQEQLERERQERERQERLERQERLERQ--------------- 213
Query: 249 SMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKL 308
ERL++Q R L+ ER R+E RL+R L
Sbjct: 214 ---------------------ERLERQER-------------LDRERQERQERERLER-L 238
Query: 309 QREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISP 368
+RE + RE RQ LE + ER + +A P +V +P+ SS+ P
Sbjct: 239 ERERQERE---RQEQLEREQLEWERERRISSAAA----PASVETPLNSVLGDSSAS--EP 289
Query: 369 GLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSN--SPDKFKRP 426
GL AS + ++ P L P P +++ P P
Sbjct: 290 GLQAASQPAETPSQQGIVLGPLAPPPPPPL------------PPGPAQASVALPPPPGPP 337
Query: 427 TPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTP 463
PPP P+T PPPPPPPPP+ VP P P
Sbjct: 338 PPPPLPST----GPPPPPPPPPLPNQVPPPPPPPPAP 370
Score = 39.3 bits (90), Expect = 0.008
Identities = 31/144 (21%), Positives = 69/144 (47%), Gaps = 11/144 (7%)
Query: 101 IQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELE 160
IQ R QE++ ++++ + E+E L + E L ++ ++ + ++ E +
Sbjct: 142 IQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQ 201
Query: 161 QHLEQEQEFQVNKLMKKIKKLENDTISKQ--LTLEQLRREKIDLENTLEQEQEALVNRLW 218
+ LE+++ + + +++ ++L+ + +Q LE+L RE+ + E + E+E L W
Sbjct: 202 ERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLE---W 258
Query: 219 KRMDKLEAEKRILQEKLDQPVSAP 242
+R E+RI V P
Sbjct: 259 ER------ERRISSAAAPASVETP 276
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 73.9 bits (180), Expect = 3e-13
Identities = 89/337 (26%), Positives = 141/337 (41%), Gaps = 82/337 (24%)
Query: 132 VNYEKEEEFLTNELSRKLMQLQH--EKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQ 189
+N ++ L + S+ Q+Q+ + ELE Q QE Q K +++ ++LE + + ++
Sbjct: 111 LNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELER-ERLERERMERE 169
Query: 190 -LTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDI 248
L E+L RE+++ E LEQEQ + +R ++LE ++R+ ++
Sbjct: 170 RLERERLERERLERER-LEQEQLERERQERERQERLERQERLERQ--------------- 213
Query: 249 SMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKL 308
ERL++Q R L+ ER R+E RL+R L
Sbjct: 214 ---------------------ERLERQER-------------LDRERQERQERERLER-L 238
Query: 309 QREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISP 368
+RE + RE RQ LE + ER + +A P +V +P+ SS+ P
Sbjct: 239 ERERQERE---RQEQLEREQLEWERERRISSAAA----PASVETPLNSVLGDSSAS--EP 289
Query: 369 GLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSN--SPDKFKRP 426
GL AS + ++ P L P P +++ P P
Sbjct: 290 GLQAASQPAETPSQQGIVLGPLAPPPPPPL------------PPGPAQASVALPPPPGPP 337
Query: 427 TPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTP 463
PPP P+T PPPPPPPPP+ VP P P
Sbjct: 338 PPPPLPST----GPPPPPPPPPLPNQVPPPPPPPPAP 370
Score = 39.3 bits (90), Expect = 0.008
Identities = 31/144 (21%), Positives = 69/144 (47%), Gaps = 11/144 (7%)
Query: 101 IQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELE 160
IQ R QE++ ++++ + E+E L + E L ++ ++ + ++ E +
Sbjct: 142 IQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQ 201
Query: 161 QHLEQEQEFQVNKLMKKIKKLENDTISKQ--LTLEQLRREKIDLENTLEQEQEALVNRLW 218
+ LE+++ + + +++ ++L+ + +Q LE+L RE+ + E + E+E L W
Sbjct: 202 ERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLE---W 258
Query: 219 KRMDKLEAEKRILQEKLDQPVSAP 242
+R E+RI V P
Sbjct: 259 ER------ERRISSAAAPASVETP 276
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 73.6 bits (179), Expect = 4e-13
Identities = 82/353 (23%), Positives = 170/353 (48%), Gaps = 44/353 (12%)
Query: 13 AGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELTNRLASLQQENKV 72
AG + S ++TSGGG G + + S + +L + SL+Q+ K
Sbjct: 42 AGAKTKKKKTDSSPETTTSGGGHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQ 101
Query: 73 LKIELET--------YKLKCKALQE------ENRDLRKASVTIQARA---EQEEEFISNT 115
++ +LE +K + + L+ E DL+ + A E+E + ++
Sbjct: 102 VEHQLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGR 161
Query: 116 LFKKIQALQK-EKETLAVNYEKEEEFLTNE-----LSRKLMQLQHEKAELEQHLEQEQEF 169
L +Q +Q+ E+ AV+ +++EE ++ L R+L Q E+A L H+ Q
Sbjct: 162 LQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLHRRLQQTIKERALLNAHVTQ---- 217
Query: 170 QVNKLMKKIKKLENDTISKQLTLEQLRRE----KIDLE-NTLEQEQEALVNRLWKRMDKL 224
V + +K+++ LE D +K + E+ R + K+ +E TL++E++ ++R+ +L
Sbjct: 218 -VTESLKQVQ-LERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRI----QEL 271
Query: 225 EAEKRILQEKLDQPVS-APPSPRDISMEI-DSPENMMRHIRFLKNEVERLKKQLRAAQLQ 282
E L+ ++ +P S APP+ + ++ D +++ + + L+ +++ + +A L
Sbjct: 272 ERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLL 331
Query: 283 HSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDER 335
E+ + E+E +RE+ ++ R+ +R E+ E +L E + +L+ ER
Sbjct: 332 SKEQKQRLQEQEEMLREQEVQRVREQERLCEQNE----RLREQQKTLQEQGER 380
Score = 51.6 bits (122), Expect = 2e-06
Identities = 64/274 (23%), Positives = 120/274 (43%), Gaps = 36/274 (13%)
Query: 59 LTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFK 118
L + + + K +++E + Y K + ++ R ++++AR +EE+
Sbjct: 211 LNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWKMSVEARTLKEEK---KRDIH 266
Query: 119 KIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKI 178
+IQ L++ L K ++ + QLQ E +HL QE E KL ++
Sbjct: 267 RIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEA----KHLRQEVEGLEGKLQSQV 322
Query: 179 KKLENDTISKQLTLEQLRREKIDLENTLEQEQEAL--VNRLWKRMDKLEAEKRILQEKLD 236
EN+ L+ EQ +R + E EQE + + RL ++ ++L +++ LQE+
Sbjct: 323 ---ENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQ-- 377
Query: 237 QPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERH 296
E + + + L+ + ERL+K+ +LQ EK EE
Sbjct: 378 ------------------GERLRKQEQRLRKQEERLRKE--EERLQKQEKRLWDQEERLW 417
Query: 297 MREENLRLQRKLQREMERREALCRQLSESESSLE 330
+EE L+ Q + + + + L +QL+E + S E
Sbjct: 418 KKEERLQKQEE-RLALSQNHKLDKQLAEPQCSFE 450
Score = 51.2 bits (121), Expect = 2e-06
Identities = 63/271 (23%), Positives = 115/271 (42%), Gaps = 45/271 (16%)
Query: 59 LTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFK 118
+T+ + LQ E K L+ E+E + K ++ E N+ L S + R +++EE + +
Sbjct: 293 VTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQ 352
Query: 119 KIQALQKEKETLAVNYEK--EEEFLTNELSRKLMQLQHEKAELEQHLEQEQEF------- 169
++ +E+E L E+ E++ E +L + + + E+ L +E+E
Sbjct: 353 RV----REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKR 408
Query: 170 ---QVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEA 226
Q +L KK ++L+ ++L L Q K+D + Q +N K +LE
Sbjct: 409 LWDQEERLWKKEERLQKQ--EERLALSQ--NHKLDKQLAEPQCSFEDLNNEKKSALQLEQ 464
Query: 227 EKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEK 286
+ + LQEKLD+ H+ + ++L+ QL L
Sbjct: 465 QVKELQEKLDE----------------------EHLEAASQQNQQLETQLSLVALPGEGD 502
Query: 287 MAQYLEEERHMREENLRLQRKLQREMERREA 317
Q+L+ E EE R + ++E REA
Sbjct: 503 GGQHLDSE---EEEAPRPTPNIPEDLESREA 530
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 73.6 bits (179), Expect = 4e-13
Identities = 83/343 (24%), Positives = 152/343 (44%), Gaps = 83/343 (24%)
Query: 54 FRLEEL-TNRLASLQQENKVLK----------IELETYKLKCKALQEENRDLRKASVTIQ 102
F L E ++R+ L++EN+ L+ + LE LKC L++EN L K +Q
Sbjct: 455 FELNECASSRILKLEKENQSLQSTIQGLRDASLVLEESGLKCGELEKENHQLSKKIEKLQ 514
Query: 103 ARAEQEE------EFISNTLFKKIQALQKEKETLAV------------------------ 132
+ E+E+ E +S L ++ + LQ + ETL
Sbjct: 515 TQLEREKQSNQDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQEKDHLNRAMWSLR 574
Query: 133 ------------NYEKEEEFL---TNELSRKLMQLQHEKAELEQHLEQEQE--FQVNKLM 175
+ EKE + L E + KL QL+ EK +L + LEQ +E + KL
Sbjct: 575 ERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHRDLEQAKEKGERAEKLE 634
Query: 176 KKIKKL--ENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQE 233
+++++L EN +++++T + EK++ LE E + L+ E R L++
Sbjct: 635 RELQRLQEENGRLARKVTSLETATEKVE---ALEHESQG-----------LQLENRTLRK 680
Query: 234 KLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLR--AAQLQHSEKMAQYL 291
LD + +++S++++ E + + E+ RL + +R + +L E+ Q L
Sbjct: 681 SLD-------TLQNVSLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQMERENQQL 733
Query: 292 EEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDE 334
E E+ +N+ L + L ++ ER E + +S L+ E
Sbjct: 734 EREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQSLE 776
Score = 35.4 bits (80), Expect = 0.11
Identities = 51/221 (23%), Positives = 94/221 (42%), Gaps = 23/221 (10%)
Query: 147 RKLMQLQHEKAELEQHLEQEQEF-QVNKLMKKIKKLENDTI---SKQLTLEQLRREKIDL 202
R+L+ + E EL L QE+++ Q IK D+ + L+ E + ++L
Sbjct: 197 RRLIDQRDECTELIVDLTQERDYLQAQHPPSPIKSSSADSTPSPTSSLSSEDKQHLAVEL 256
Query: 203 ENT----------LEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEI 252
+T LE + E LV+ + +D+L E + ++++ Q + S R E+
Sbjct: 257 ADTKARLRRVRQELEDKTEQLVDTRHE-VDQLVLELQKVKQENIQLAADARSARAYRDEL 315
Query: 253 DSPENMMRHIRFLKNEVERLKKQLR-----AAQLQHSEKMAQYLEEERHMREENLRLQRK 307
DS + L+ E+ R K++L A+++ + L E + M EE L R
Sbjct: 316 DSLREKANRVERLELELTRCKEKLHDVDFYKARMEELREDNIILIETKAMLEEQLTAARA 375
Query: 308 LQREMERREALCRQLSESESSLEMD---DERYFNEMSAQGL 345
++ E QL LE+D D++ E+ + +
Sbjct: 376 RGDKVHELEKENLQLKSKLHDLELDRDTDKKRIEELLEENM 416
Score = 34.3 bits (77), Expect = 0.25
Identities = 55/265 (20%), Positives = 111/265 (41%), Gaps = 25/265 (9%)
Query: 59 LTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFK 118
L N + + EN+ L+ + E +AL +++ L T+ R E E L +
Sbjct: 1139 LQNHHTAKETENESLQRQQEQLTAAYEALLQDHEHLG----TLHERQSAEYE----ALIR 1190
Query: 119 KIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKL-MKK 177
+ L+ L + +++ E + L RK + EK + +QE + N L M +
Sbjct: 1191 QHSCLKTLHRNLELEHKELGERHGDMLKRKAELEEREKVLTTEREALQQEQRTNALAMGE 1250
Query: 178 IKKLENDTISKQLTLEQLRREKIDLENTLEQEQEAL------VNRLWKRMDKLEAEKRIL 231
++L + QL+ E +L ++ + +L +NR R D+L+ + + +
Sbjct: 1251 NQRLRGELDRVNFLHHQLKGEYEELHAHTKELKTSLNNAQLELNRWQARFDELKEQHQTM 1310
Query: 232 QEKLDQPVSAPPSPRDISMEIDS--PENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQ 289
L + D E+ S N+ L ++++ L +Q + Q+ E Q
Sbjct: 1311 DISLTK--------LDNHCELLSRLKGNLEEENHHLLSQIQLLSQQNQMLLEQNMENKEQ 1362
Query: 290 YLEEERHMREENLRLQRKLQREMER 314
Y EE++ ++ L+R ++ E+
Sbjct: 1363 YHEEQKQYIDKLNALRRHKEKLEEK 1387
Score = 33.5 bits (75), Expect = 0.43
Identities = 73/334 (21%), Positives = 134/334 (40%), Gaps = 65/334 (19%)
Query: 49 IVISPFRLEELTNRLASLQQENKVLKIELETY--------KLKCKALQEENRDLRKASVT 100
+V+ + ++L++ L L QE + + + E K K L+ N K ++
Sbjct: 914 LVLEKLKSQQLSSELDKLSQELEKVGLNRELLLQEDDSGSDTKYKILEGRNESALKTTLA 973
Query: 101 IQAR------AEQEEEF-ISNTLFKKIQALQKEKETLAVNYEKEEEFLTN---------- 143
++ A+ EE+ ++ L ++Q L+KE ETL N + E + L N
Sbjct: 974 MKEEKIVLLEAQMEEKASLNRQLESELQMLKKECETLRQN-QGEGQHLQNSFKHPAGKTA 1032
Query: 144 --------------ELSRKLMQLQHEKAELEQ-HLEQEQEFQVNKLMKKIKKLENDTISK 188
E + +L++++ ELE+ + + E Q+ K + + +N T S
Sbjct: 1033 ASHQGKEAWGPGHKEATMELLRVKDRAIELERNNAALQAEKQLLKEQLQHLETQNVTFSS 1092
Query: 189 Q-LTLE-------------QLRREKIDLEN-TLEQEQEALVNR---LWKRMDKLEAEKRI 230
Q LTL+ Q + K+ +EN TL + AL + L E E
Sbjct: 1093 QILTLQKQSAFLQEHNTTLQTQTAKLQVENSTLSSQSAALTAQYTLLQNHHTAKETENES 1152
Query: 231 LQEKLDQPVSAPPSPRDISMEIDS-PENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQ 289
LQ + +Q +A + + + E L + LK R +L+H E +
Sbjct: 1153 LQRQQEQLTAAYEALLQDHEHLGTLHERQSAEYEALIRQHSCLKTLHRNLELEHKELGER 1212
Query: 290 Y-----LEEERHMREENLRLQRKLQREMERREAL 318
+ + E RE+ L +R+ ++ +R AL
Sbjct: 1213 HGDMLKRKAELEEREKVLTTEREALQQEQRTNAL 1246
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 73.2 bits (178), Expect = 5e-13
Identities = 82/353 (23%), Positives = 169/353 (47%), Gaps = 44/353 (12%)
Query: 13 AGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELTNRLASLQQENKV 72
AG + S ++TSGGG G + + S + +L + SL+Q+ K
Sbjct: 42 AGAKTKKKKTDSSPETTTSGGGHSPGDSQYQELAVALESSSVTINQLNENIESLKQQKKQ 101
Query: 73 LKIELET--------YKLKCKALQE------ENRDLRKASVTIQARA---EQEEEFISNT 115
++ +LE +K + + L+ E DL+ + A E+E + ++
Sbjct: 102 VEHQLEEAKKTNNEIHKAQMEQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGR 161
Query: 116 LFKKIQALQK-EKETLAVNYEKEEEFLTNE-----LSRKLMQLQHEKAELEQHLEQEQEF 169
L +Q +Q+ E+ AV+ +++EE ++ L R+L Q E+A L H+ Q
Sbjct: 162 LQYSLQHIQELERALCAVSTQQQEEDRSSSCREAVLQRRLQQTIKERALLNAHVTQ---- 217
Query: 170 QVNKLMKKIKKLENDTISKQLTLEQLRRE----KIDLE-NTLEQEQEALVNRLWKRMDKL 224
V + +K+++ LE D +K + E+ R + K+ +E TL++E++ ++R+ +L
Sbjct: 218 -VTESLKQVQ-LERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRI----QEL 271
Query: 225 EAEKRILQEKLDQPVS-APPSPRDISMEI-DSPENMMRHIRFLKNEVERLKKQLRAAQLQ 282
E L+ ++ +P S APP+ + ++ D +++ + + L+ +++ + +A L
Sbjct: 272 ERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLL 331
Query: 283 HSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDER 335
E+ + E+E +RE+ + R+ +R E+ E +L E + +L+ ER
Sbjct: 332 SKEQKQRLQEQEEMLREQEAQRVREQERLCEQNE----RLREQQKTLQEQGER 380
Score = 50.4 bits (119), Expect = 3e-06
Identities = 63/274 (22%), Positives = 120/274 (43%), Gaps = 36/274 (13%)
Query: 59 LTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFK 118
L + + + K +++E + Y K + ++ R ++++AR +EE+
Sbjct: 211 LNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWKMSVEARTLKEEK---KRDIH 266
Query: 119 KIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKI 178
+IQ L++ L + ++ + QLQ E +HL QE E KL ++
Sbjct: 267 RIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEA----KHLRQEVEGLEGKLQSQV 322
Query: 179 KKLENDTISKQLTLEQLRREKIDLENTLEQEQEAL--VNRLWKRMDKLEAEKRILQEKLD 236
EN+ L+ EQ +R + E EQE + + RL ++ ++L +++ LQE+
Sbjct: 323 ---ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQ-- 377
Query: 237 QPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERH 296
E + + + L+ + ERL+K+ +LQ EK EE
Sbjct: 378 ------------------GERLRKQEQRLRKQEERLRKE--EERLQKQEKRLWDQEERLW 417
Query: 297 MREENLRLQRKLQREMERREALCRQLSESESSLE 330
+EE L+ Q + + + + L +QL+E + S E
Sbjct: 418 KKEERLQKQEE-RLALSQNHKLDKQLAEPQCSFE 450
Score = 50.1 bits (118), Expect = 4e-06
Identities = 63/271 (23%), Positives = 114/271 (42%), Gaps = 45/271 (16%)
Query: 59 LTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFK 118
+T+ + LQ E K L+ E+E + K ++ E N+ L S + R +++EE + +
Sbjct: 293 VTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQ 352
Query: 119 KIQALQKEKETLAVNYEK--EEEFLTNELSRKLMQLQHEKAELEQHLEQEQEF------- 169
++ +E+E L E+ E++ E +L + + + E+ L +E+E
Sbjct: 353 RV----REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKR 408
Query: 170 ---QVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEA 226
Q +L KK ++L+ ++L L Q K+D + Q +N K +LE
Sbjct: 409 LWDQEERLWKKEERLQKQ--EERLALSQ--NHKLDKQLAEPQCSFEDLNNEKKSALQLEQ 464
Query: 227 EKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEK 286
+ + LQEKLD+ H+ ++L+ QL L
Sbjct: 465 QVKELQEKLDE----------------------EHLEAASQRNQQLETQLSLVALPGEGD 502
Query: 287 MAQYLEEERHMREENLRLQRKLQREMERREA 317
Q+L+ E EE R + ++E REA
Sbjct: 503 GGQHLDSE---EEEAPRPTPNIPEDLESREA 530
Score = 38.5 bits (88), Expect = 0.013
Identities = 44/172 (25%), Positives = 79/172 (45%), Gaps = 17/172 (9%)
Query: 57 EELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTI---QARAEQEEEFI- 112
E L + A +E + L + E + + K LQE+ LRK + + R +EEE +
Sbjct: 344 EMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQ 403
Query: 113 ---------SNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEK---AELE 160
L+KK + LQK++E LA++ + + E L +EK +LE
Sbjct: 404 KQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLE 463
Query: 161 QHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEA 212
Q +++ QE ++++ + N + QL+L L E ++ +E+EA
Sbjct: 464 QQVKELQE-KLDEEHLEAASQRNQQLETQLSLVALPGEGDGGQHLDSEEEEA 514
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 73.2 bits (178), Expect = 5e-13
Identities = 82/353 (23%), Positives = 169/353 (47%), Gaps = 44/353 (12%)
Query: 13 AGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELTNRLASLQQENKV 72
AG + S ++TSGGG G + + S + +L + SL+Q+ K
Sbjct: 42 AGAKTKKKKTDSSPETTTSGGGHSPGDSQYQELAVALESSSVTINQLNENIESLKQQKKQ 101
Query: 73 LKIELET--------YKLKCKALQE------ENRDLRKASVTIQARA---EQEEEFISNT 115
++ +LE +K + + L+ E DL+ + A E+E + ++
Sbjct: 102 VEHQLEEAKKTNNEIHKAQMEQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGR 161
Query: 116 LFKKIQALQK-EKETLAVNYEKEEEFLTNE-----LSRKLMQLQHEKAELEQHLEQEQEF 169
L +Q +Q+ E+ AV+ +++EE ++ L R+L Q E+A L H+ Q
Sbjct: 162 LQYSLQRIQELERALSAVSTQQQEEDRSSSCREAVLQRRLQQTIKERALLNAHVTQ---- 217
Query: 170 QVNKLMKKIKKLENDTISKQLTLEQLRRE----KIDLE-NTLEQEQEALVNRLWKRMDKL 224
V + +K+++ LE D +K + E+ R + K+ +E TL++E++ ++R+ +L
Sbjct: 218 -VTESLKQVQ-LERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRI----QEL 271
Query: 225 EAEKRILQEKLDQPVS-APPSPRDISMEI-DSPENMMRHIRFLKNEVERLKKQLRAAQLQ 282
E L+ ++ +P S APP+ + ++ D +++ + + L+ +++ + +A L
Sbjct: 272 ERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLL 331
Query: 283 HSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDER 335
E+ + E+E +RE+ + R+ +R E+ E +L E + +L+ ER
Sbjct: 332 SKEQKQRLQEQEEMLREQEAQRVREQERLCEQNE----RLREQQKTLQEQGER 380
Score = 50.4 bits (119), Expect = 3e-06
Identities = 63/274 (22%), Positives = 120/274 (43%), Gaps = 36/274 (13%)
Query: 59 LTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFK 118
L + + + K +++E + Y K + ++ R ++++AR +EE+
Sbjct: 211 LNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWKMSVEARTLKEEK---KRDIH 266
Query: 119 KIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKI 178
+IQ L++ L + ++ + QLQ E +HL QE E KL ++
Sbjct: 267 RIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEA----KHLRQEVEGLEGKLQSQV 322
Query: 179 KKLENDTISKQLTLEQLRREKIDLENTLEQEQEAL--VNRLWKRMDKLEAEKRILQEKLD 236
EN+ L+ EQ +R + E EQE + + RL ++ ++L +++ LQE+
Sbjct: 323 ---ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQ-- 377
Query: 237 QPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERH 296
E + + + L+ + ERL+K+ +LQ EK EE
Sbjct: 378 ------------------GERLRKQEQRLRKQEERLRKE--EERLQKQEKRLWDQEERLW 417
Query: 297 MREENLRLQRKLQREMERREALCRQLSESESSLE 330
+EE L+ Q + + + + L +QL+E + S E
Sbjct: 418 KKEERLQKQEE-RLALSQNHKLDKQLAEPQCSFE 450
Score = 50.1 bits (118), Expect = 4e-06
Identities = 63/271 (23%), Positives = 114/271 (42%), Gaps = 45/271 (16%)
Query: 59 LTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFK 118
+T+ + LQ E K L+ E+E + K ++ E N+ L S + R +++EE + +
Sbjct: 293 VTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQ 352
Query: 119 KIQALQKEKETLAVNYEK--EEEFLTNELSRKLMQLQHEKAELEQHLEQEQEF------- 169
++ +E+E L E+ E++ E +L + + + E+ L +E+E
Sbjct: 353 RV----REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKR 408
Query: 170 ---QVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEA 226
Q +L KK ++L+ ++L L Q K+D + Q +N K +LE
Sbjct: 409 LWDQEERLWKKEERLQKQ--EERLALSQ--NHKLDKQLAEPQCSFEDLNNEKKSALQLEQ 464
Query: 227 EKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEK 286
+ + LQEKLD+ H+ ++L+ QL L
Sbjct: 465 QVKELQEKLDE----------------------EHLEAASQRNQQLETQLSLVALPGEGD 502
Query: 287 MAQYLEEERHMREENLRLQRKLQREMERREA 317
Q+L+ E EE R + ++E REA
Sbjct: 503 GGQHLDSE---EEEAPRPTPNIPEDLESREA 530
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 73.2 bits (178), Expect = 5e-13
Identities = 69/285 (24%), Positives = 137/285 (48%), Gaps = 20/285 (7%)
Query: 57 EELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQ--EEEFISN 114
EE+ +LA+ + N+ L+++L + + L+E N++L+KA +Q ++ + E ++
Sbjct: 315 EEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNS 374
Query: 115 TLFKKIQALQKEKETLAVNYEKEE----EFLTNELSRKLMQLQHEKAELEQHLE--QEQE 168
+L +++ L+ K L + + EE E EL +KL + +H EL +E Q++
Sbjct: 375 SLMAEVENLR--KRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRM 432
Query: 169 FQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLE-AE 227
++ KL + K +++ L LE+ + DL N LE + R+ +LE +E
Sbjct: 433 SELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVK--------SRVKELECSE 484
Query: 228 KRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKM 287
R+ + +L M +D +NMM I+ + +V+ L K + Q + +
Sbjct: 485 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 544
Query: 288 AQYLEEERHMREENLRLQRKLQREMERREALCRQL-SESESSLEM 331
+ +EE + + + ++ K+ R+ L +L SE E S E+
Sbjct: 545 EKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSEL 589
Score = 55.8 bits (133), Expect = 8e-08
Identities = 71/312 (22%), Positives = 135/312 (43%), Gaps = 51/312 (16%)
Query: 44 GKSGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQ--EENRDLRKASVTI 101
GK I + + EL +L + +K L++E+E + + L+ EE K+ T
Sbjct: 392 GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQ 451
Query: 102 QARAEQEEEFISNTLFKKIQALQ---KEKETLAVNYEKEEEFLTNELSRK---LMQLQHE 155
++E+ ++ L +++ ++ KE E EK E L ++L++ + L E
Sbjct: 452 LHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDE 511
Query: 156 KAELEQHLEQEQ--------EFQV---------NKLMKKIKKLENDTISKQLTLEQLRRE 198
+ + + ++QE+ F+V KL+++ KKL + + L RE
Sbjct: 512 RKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRE 571
Query: 199 KIDLENTLEQEQE------ALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEI 252
+ +L L+ E+E V+ L KR+D +E +R + + S P D
Sbjct: 572 RDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPED----- 626
Query: 253 DSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREM 312
I+ L E+ERLKK+L+ ++ + M +E +L++K + E
Sbjct: 627 -------NKIKELTLEIERLKKRLQQLEVVEGDLM--------KTEDEYDQLEQKFRTEQ 671
Query: 313 ERREALCRQLSE 324
++ L +QL E
Sbjct: 672 DKANFLSQQLEE 683
Score = 42.7 bits (99), Expect = 7e-04
Identities = 54/241 (22%), Positives = 104/241 (43%), Gaps = 25/241 (10%)
Query: 93 DLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRK---L 149
D+ + ++ R E++++ + +++ +K E E+ T+ +++
Sbjct: 142 DVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFT 201
Query: 150 MQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQE 209
L+ E+ L++ LEQE+ +Q K + K+L N + + L+ +D E + E
Sbjct: 202 NLLEQERERLKKLLEQEKAYQARKEKENAKRL-NKLRDELVKLKSFALMLVD-ERQMHIE 259
Query: 210 QEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEV 269
Q L ++ ++ L + R +EKL S R + LK EV
Sbjct: 260 QLGLQSQ---KVQDLTQKLREEEEKLKAITSKSKEDRQ---------------KLLKLEV 301
Query: 270 ERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSL 329
+ K R +Q +H E A+ +E H R+ L+L QR +E E + L ++E L
Sbjct: 302 DFEHKASRFSQ-EHEEMNAKLANQESHNRQLRLKLVGLTQR-IEELEETNKNLQKAEEEL 359
Query: 330 E 330
+
Sbjct: 360 Q 360
>gi|122937271 WAS protein homolog associated with actin, golgi
membranes and microtubules [Homo sapiens]
Length = 809
Score = 72.8 bits (177), Expect = 6e-13
Identities = 94/424 (22%), Positives = 167/424 (39%), Gaps = 71/424 (16%)
Query: 85 KALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNY---------- 134
K +E R +A V+IQ + + T+ K + +QKE E A +
Sbjct: 279 KEAEEWTRRAEEAVVSIQ---DITVNYFKETV-KALAGMQKEMEQDAKRFGQAAWATAIP 334
Query: 135 --EKEEEFLTNE----LSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISK 188
EK + L E + K + L H++AE++ +E E + N + + +LE
Sbjct: 335 RLEKLQLMLARETLQLMRAKELCLNHKRAEIQGKMEDLPEQEKNTNV--VDELEIQFYEI 392
Query: 189 QLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDI 248
QL L +++ E + E L Q L++ KR+++EK D+ V P
Sbjct: 393 QLELYEVKFEILKNEEILLTTQ-------------LDSLKRLIKEKQDEVVYYDPCENPE 439
Query: 249 SMEI--------DSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEER---HM 297
+++ D ++ +R ++E + ++ A + + Q E R
Sbjct: 440 ELKVIDCVVGLQDDKNLEVKELRRQCQQLESKRGRICAKRASLRSRKDQCKENHRFRLQQ 499
Query: 298 REENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMS-------AQGLRPRTV 350
EE++R R+ +R+ + + + + + + ++ + AQ +R +
Sbjct: 500 AEESIRYSRQHHSIQMKRDKIKEEEQKKKEWINQERQKTLQRLRSFKDKRLAQSVRNTSG 559
Query: 351 SSPI-PYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHG- 408
S P+ P PS S + P ASH V P+S G+ + + HG
Sbjct: 560 SEPVAPNLPSDLSQQMCLP----ASHAVSVIHPSSRKTRGVPLSEAGNVKSPKCQNCHGN 615
Query: 409 ------ITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPT 462
+ S S ++ P PPP P PPPPPPPPP P +++SQ
Sbjct: 616 IPVQVFVPVGDQTHSKSSEELSLPPPPPPP------PPPPPPPPPPPPPLRALSSSSQAA 669
Query: 463 PSQH 466
Q+
Sbjct: 670 THQN 673
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 72.4 bits (176), Expect = 8e-13
Identities = 88/318 (27%), Positives = 144/318 (45%), Gaps = 58/318 (18%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKC---KALQEENRDL-RKASVTIQARAEQEEEF 111
LEE ++ +L++ENK L E+ YK C K L++EN++L ++A++ I+ E+
Sbjct: 852 LEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDL 911
Query: 112 ISNTLFKKIQALQKEKETLAVNYEK----EEEFLTNELSRKLMQLQHEKAELEQHLEQEQ 167
+S L K Q + + E L EK +E L +E S + + +++LE L++
Sbjct: 912 VSEKL--KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSL 969
Query: 168 EFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAE 227
E + K+ +LE T Q QLR+E T+++ EAL R + E
Sbjct: 970 EIKEEKIAALEARLEESTNYNQ----QLRQEL----KTVKKNYEALKQR--------QDE 1013
Query: 228 KRILQEKLDQPVSAPPSPRDISMEIDSPE-------------NMMRHIRFLKNEVERLKK 274
+R++Q S P S D E +S E + R+ L+ E + LK
Sbjct: 1014 ERMVQS------SPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKT 1067
Query: 275 QLRAAQLQHSEKMAQYLEEERH---MREENLRLQ---RKLQREMERREALC-------RQ 321
QL+ + Q++ AQ L +R ++E+N LQ KLQ E + Q
Sbjct: 1068 QLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ 1127
Query: 322 LSESESSLEMDDERYFNE 339
L +SSLE ++E E
Sbjct: 1128 LLIQQSSLENENESVIKE 1145
Score = 69.7 bits (169), Expect = 5e-12
Identities = 73/277 (26%), Positives = 136/277 (49%), Gaps = 20/277 (7%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKC---KALQEENRDLRKASVTIQARAEQEEEF 111
R EEL N L L++EN++L+ ++ K+ C +AL++EN +L + + + ++ +
Sbjct: 626 RAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELEREN----RKLKKTLDS 681
Query: 112 ISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELE-QHLEQEQEFQ 170
N F ++++L+KE L E+ E N S K ++ + +LE + LE E+E Q
Sbjct: 682 FKNLTF-QLESLEKENSQLD---EENLELRRNVESLKCASMKMAQLQLENKELESEKE-Q 736
Query: 171 VNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRI 230
+ K ++ +K T +++ + L E L+ TLE + + +L + LE E +
Sbjct: 737 LKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKK-IQQLESELQDLEMENQT 795
Query: 231 LQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQY 290
LQ+ L++ + + E S E + K ++E+ K+LR Q +E
Sbjct: 796 LQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR----QQAEIKDTT 851
Query: 291 LEEERHMREENLRLQRK-LQREMERREALCRQLSESE 326
L EE +++ NL + K L +E+ + C +L E E
Sbjct: 852 L-EENNVKIGNLEKENKTLSKEIGIYKESCVRLKELE 887
Score = 63.2 bits (152), Expect = 5e-10
Identities = 60/275 (21%), Positives = 135/275 (49%), Gaps = 36/275 (13%)
Query: 62 RLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFIS--NTLFKK 119
R+ +++ENK+L ++ K ++ E R ++K + + E+ EE + + L K+
Sbjct: 581 RVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE 640
Query: 120 IQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLE--QEQEFQVNKLMKK 177
+ LQK+ L + EK E L ++ +L+ E +L++ L+ + FQ+ L K+
Sbjct: 641 NELLQKKITNLKITCEKIE-----ALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Query: 178 IKKLENDTISKQLTLEQL-----RREKIDLEN-TLEQEQEALVNRL------WKRMDKLE 225
+L+ + + + +E L + ++ LEN LE E+E L L +K+ ++LE
Sbjct: 696 NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLE 755
Query: 226 A-------EKRILQEKLDQP----VSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKK 274
E + LQ+ L+ +D+ ME + + + ++ +E+L+K
Sbjct: 756 VSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEK 815
Query: 275 QLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQ 309
+ ++ + ++ +Q ++++ + +EN RL+++ +
Sbjct: 816 ENKSLE----QETSQLEKDKKQLEKENKRLRQQAE 846
Score = 59.3 bits (142), Expect = 7e-09
Identities = 84/343 (24%), Positives = 142/343 (41%), Gaps = 56/343 (16%)
Query: 54 FRLEELTNRLASLQQENKVLKIELETYK---LKCKALQEENRDLR-------------KA 97
F+LE L + L +EN L+ +E+ K +K LQ EN++L KA
Sbjct: 687 FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKA 746
Query: 98 SVTIQARAEQ-------EEEFISNTL---FKKIQALQKEKETLAVNYEKEEEFLTNEL-- 145
S R E E + + TL KKIQ L+ E + L E E + L L
Sbjct: 747 SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDL----EMENQTLQKNLEE 802
Query: 146 ----SRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQ--LRREK 199
S++L QL+ E LEQ Q E +L K+ K+L K TLE+ ++
Sbjct: 803 LKISSKRLEQLEKENKSLEQETSQ-LEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN 861
Query: 200 IDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPR-DISMEIDSPENM 258
++ EN ++ + R+ +LE E + L ++ + + R D+ E + M
Sbjct: 862 LEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM 921
Query: 259 MRHIRFLKNEVERLKKQLRAAQLQHSE-------------KMAQYLEEERHMREENL-RL 304
+ L +E+E++ L +L H E K+ L++ ++EE + L
Sbjct: 922 NNDLEKLTHELEKI--GLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAAL 979
Query: 305 QRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRP 347
+ +L+ + L ++L + + E +R E Q P
Sbjct: 980 EARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPP 1022
Score = 52.0 bits (123), Expect = 1e-06
Identities = 71/314 (22%), Positives = 144/314 (45%), Gaps = 50/314 (15%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRD-----------------LRKAS 98
LEE T +L +QE + ++IEL K LQ+EN + LR+ +
Sbjct: 267 LEEKTEQLLDCKQELEQMEIEL-------KRLQQENMNLLSDARSARMYRDELDALREKA 319
Query: 99 VTI---QARAEQEEEFISNTLFKK--IQALQKEKETLAVNYEKEEEFL--TNELSRKLMQ 151
V + ++ + +E + + F K ++ L+++ + L E+ L T S KL +
Sbjct: 320 VRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379
Query: 152 LQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQ--- 208
L+ E +L+ L + E + + KKI++L + ++ ++ +Q E + L LEQ
Sbjct: 380 LEKENLQLKAKL-HDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISR 438
Query: 209 ---EQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFL 265
EA L +++L + + + E +Q S + ++ +DS E I +
Sbjct: 439 TSELSEAPQKSLGHEVNELTSSRLLKLEMENQ--SLTKTVEELRTTVDSVEGNASKILKM 496
Query: 266 KNEVERLKKQLRAAQ---------LQHSEKMAQYLEEERHMREENLR-LQRKLQREMERR 315
+ E +RL K++ + LQ+ + +++ L +E+ E+ + L+ +R+++
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 556
Query: 316 EALCRQLSESESSL 329
E L+++ SSL
Sbjct: 557 EQENEHLNQTVSSL 570
Score = 49.7 bits (117), Expect = 6e-06
Identities = 61/287 (21%), Positives = 112/287 (39%), Gaps = 37/287 (12%)
Query: 56 LEELTN-RLASLQQENKVLKIELETYKL----------KCKALQEENRDLRKASVTIQAR 104
+ ELT+ RL L+ EN+ L +E + K +++EN+ L K ++
Sbjct: 454 VNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENE 513
Query: 105 AEQEEEFISNT-------------LFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQ 151
QE++ + N L K I+ L++ E E+E E L +S
Sbjct: 514 IVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVS----- 568
Query: 152 LQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLE--QE 209
L Q + E +V + K+ K L L ++ EK ++ LE +E
Sbjct: 569 ------SLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKE 622
Query: 210 QEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEV 269
+ L + LE E +LQ+K+ + E E R ++ +
Sbjct: 623 KGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSF 682
Query: 270 ERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERRE 316
+ L QL + + ++S+ + LE R++ + Q ++E +E
Sbjct: 683 KNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKE 729
Score = 48.5 bits (114), Expect = 1e-05
Identities = 69/318 (21%), Positives = 135/318 (42%), Gaps = 73/318 (22%)
Query: 62 RLASLQQENKVL---KIELETYKLKCKALQEENRDLRKASVTIQARA-----------EQ 107
R+ L+++N+VL K LE +A ++ +L K ++ ++A+ ++
Sbjct: 345 RVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKK 404
Query: 108 EEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSR----------------KLMQ 151
EE + + ++ Q E+L + +E E+ T+ELS +L++
Sbjct: 405 IEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLK 464
Query: 152 LQHEKAELEQHLEQ----------------EQEFQVNKLMKKIKKLENDTISKQLTLEQ- 194
L+ E L + +E+ + E + +L KK++ LEN+ + ++ +L+
Sbjct: 465 LEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNC 524
Query: 195 ------LRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDI 248
L +EK LE T+E +E +++ LE E E L+Q VS+ I
Sbjct: 525 QNLSKDLMKEKAQLEKTIETLRE----NSERQIKILEQEN----EHLNQTVSSLRQRSQI 576
Query: 249 SMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKL 308
S E ++E+ K L + + S K+++ E+R +++E + K
Sbjct: 577 SAEARV------------KDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG 624
Query: 309 QREMERREALCRQLSESE 326
+R E L E+E
Sbjct: 625 ERAEELENELHHLEKENE 642
Score = 47.4 bits (111), Expect = 3e-05
Identities = 71/303 (23%), Positives = 129/303 (42%), Gaps = 42/303 (13%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQ----------EENRDLRKASVTIQAR 104
RLEE TN L+QE K +K E K + + E+N+ R++ T +
Sbjct: 982 RLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTREL 1041
Query: 105 AEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLE 164
+ ++ I + + LQ EK+ L K+ E N L +++ LQ + L
Sbjct: 1042 LKVKDRLIE--VERNNATLQAEKQALKTQL-KQLETQNNNLQAQILALQRQTVSL----- 1093
Query: 165 QEQEFQVNKLMKKIKKLENDTISKQLT-LEQLRREKIDLENTLEQEQEALVNR------L 217
QEQ + K+ ++EN T++ Q T L + + +++LE E E+++ L
Sbjct: 1094 QEQNTTLQTQNAKL-QVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSL 1152
Query: 218 WKRMDKLEAEKRILQEK--------LDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEV 269
+ + K + +L E+ + + + + +++ +E E+ + K ++
Sbjct: 1153 YDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQL 1212
Query: 270 ERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSL 329
E L+K L+ Q EKM LE + H E +KL E +R QL + L
Sbjct: 1213 EDLEKMLKVEQ----EKM--LLENKNH--ETVAAEYKKLCGENDRLNHTYSQLLKETEVL 1264
Query: 330 EMD 332
+ D
Sbjct: 1265 QTD 1267
Score = 40.0 bits (92), Expect = 0.005
Identities = 48/217 (22%), Positives = 96/217 (44%), Gaps = 35/217 (16%)
Query: 175 MKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEK 234
MK+ + ++ ++ ++RR + +LE EQ + + ++++E E + LQ++
Sbjct: 240 MKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCK-----QELEQMEIELKRLQQE 294
Query: 235 LDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLR-----AAQLQHSEKMAQ 289
+S S R E+D+ + L++EV R K++L A+++ ++ Q
Sbjct: 295 NMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQ 354
Query: 290 YLEEERHMRE------------------ENLRLQRKL-----QREMERREALCRQLSESE 326
L E + M E ENL+L+ KL +R+M+R++ +L E
Sbjct: 355 VLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKK--IEELMEEN 412
Query: 327 SSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSS 363
+LEM ++ +E G +S + +P S
Sbjct: 413 MTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKS 449
Score = 35.0 bits (79), Expect = 0.15
Identities = 46/186 (24%), Positives = 79/186 (42%), Gaps = 24/186 (12%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
R +L + L+ K+LK+E E L+ K + + +K E + +++
Sbjct: 1201 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLC--------GENDRLNH 1252
Query: 115 TLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKL 174
T + L KE E L +++ + L N KL Q + E AE + EQ Q+ +
Sbjct: 1253 TYSQ----LLKETEVLQTDHKNLKSLLNNS---KLEQTRLE-AEFSKLKEQYQQLDITST 1304
Query: 175 MKKIKKLENDT-ISKQL--TLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRIL 231
KL N + QL LE+ R +D TL + L+ + + D E+R
Sbjct: 1305 -----KLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQY 1359
Query: 232 QEKLDQ 237
+KL++
Sbjct: 1360 IDKLNE 1365
>gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]
Length = 388
Score = 72.4 bits (176), Expect = 8e-13
Identities = 91/388 (23%), Positives = 162/388 (41%), Gaps = 69/388 (17%)
Query: 85 KALQEENRDLRKASVTIQAR---AEQEEEF---ISNTLFKKIQALQKEKETLAVNYEKEE 138
KALQEE K I+ R AE E E + N +++ L+ E+E + ++++K
Sbjct: 18 KALQEELTVKEKQEEDIKRRINLAENELEITKTLLNQTREEVLTLKNERELMLISHQKSI 77
Query: 139 EFLTNELSRKLMQLQHEKAELEQHLEQEQ-----EFQVNKLM-KKIKKLENDTISK--QL 190
E L L +KL+ + K ++E L +E+ EF+ L+ K+ KL+ D + Q
Sbjct: 78 EQLQETLRQKLLSDDNWKEKIEAELAKERAQHLVEFEEQALLFKEETKLQLDIEKEKHQD 137
Query: 191 TLEQLRREKIDLE-----------NTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPV 239
+++ ++E+ +L+ L QE L +L K + E +++++
Sbjct: 138 VIQKYKKEQEELQMKISDLITGATRDLRQEVTTLKEKLHKSHTRYTEESNSKEKEIENLK 197
Query: 240 S-APPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMR 298
+ + EIDS +++ ++R E+E+ +L+ L + Q +E+ +
Sbjct: 198 NLVAEFESRLKKEIDSNDSVSENLR---KEMEQKSDELKRVMLAQT----QLIEQFNQSQ 250
Query: 299 EENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTP 358
EEN LQ ++RE E R L LS++ L L + +P++P
Sbjct: 251 EENTFLQETVRRECEERFELTEALSQAREQL---------------LELSKLRGSLPFSP 295
Query: 359 -SPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRS 417
S S SP + ++H SL R + + GI P+ R
Sbjct: 296 CSLSKGSLTSPAAAVSNH-----GERSLAR---------------LNSEKGIQIPNLRGV 335
Query: 418 NSPDKFKRPTPPPSPNTQTPVQPPPPPP 445
+ P F P + P+ P P PP
Sbjct: 336 SKPTTFPTSDKPKRVRSGVPILPQPHPP 363
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 70.9 bits (172), Expect = 2e-12
Identities = 78/301 (25%), Positives = 146/301 (48%), Gaps = 32/301 (10%)
Query: 57 EELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTL 116
+EL +Q+ + L+ E + + + +EE R+ ++ Q R EQ+EE L
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQ----EEERREQQEERREQQERREQQEERREQQL 339
Query: 117 FK-----KIQALQKEKET----LAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQ 167
+ + Q L++E+E + E+EEE +L R+ + ++ EQ L +EQ
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399
Query: 168 EFQVNKLMKKIKKLENDTISKQLTLEQ-LRREKIDLENTLEQEQEALVNRLWKRMDKLEA 226
+ + + +++ ++L + +QL EQ LRRE+ + + + EQE R +R+ + +
Sbjct: 400 QLRREQQLRREQQLRRE---QQLRREQQLRREQEEERHEQKHEQE----RREQRLKREQE 452
Query: 227 EKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVE-------RLKKQLRAA 279
E+R ++ ++ R ++ D E R R+LK E E R ++QLR
Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEE--RRERWLKLEEEERREQQERREQQLRRE 510
Query: 280 QLQHSEKMAQYLEEERHMREENLRLQRKLQREM-ERREALCRQLSESESSLEMDDERYFN 338
Q + E+ + EEE + ++ LR +++L+RE ERRE L ++ E E ++R
Sbjct: 511 QEERREQRLKRQEEEERL-QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 339 E 339
E
Sbjct: 570 E 570
Score = 70.1 bits (170), Expect = 4e-12
Identities = 76/265 (28%), Positives = 133/265 (50%), Gaps = 37/265 (13%)
Query: 66 LQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQK 125
L++E + + E E K + K QEE R R + + R EQ+E ++ Q L++
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE--------RREQQLRR 509
Query: 126 EKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKI--KKLEN 183
E+E E+ E+ L + + +Q ++ EQ L +EQE + +L+K+ K+LE
Sbjct: 510 EQE------ERREQRLKRQEEEERLQ---QRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Query: 184 DTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPP 243
+ ++L EQ R + L++E+E RL KR + E+R+ +E++++
Sbjct: 561 ERREQRLKREQEERR----DQLLKREEERRQQRL-KREQEERLEQRLKREEVER--LEQE 613
Query: 244 SPRDISMEIDSPENMMRHIRFLKNE--VERLKKQLRAAQLQHSEKMAQYLEEERHMREEN 301
R+ ++ + PE R + LK+E ER ++QLR Q + E+ + EE EE
Sbjct: 614 ERREQRLKREEPEEERRQ-QLLKSEEQEERRQQQLRREQQERREQRLKREEE-----EER 667
Query: 302 LRLQRKLQREMERREALCRQLSESE 326
L + K + E ERRE ++L+E E
Sbjct: 668 LEQRLKREHEEERRE---QELAEEE 689
Score = 68.6 bits (166), Expect = 1e-11
Identities = 75/290 (25%), Positives = 133/290 (45%), Gaps = 20/290 (6%)
Query: 57 EELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTL 116
+E R L++E + L+ E + + LQEE LRK R QEEE L
Sbjct: 244 KEWRKRETVLRKEEEKLQ---EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 117 FKKIQALQKEKETLAVNYEK---EEEFLTNELSRKLMQLQHEKAEL-EQHLEQEQEFQVN 172
++ Q +K++E E+ ++E + R+ QL+ E+ E EQ L +EQE +
Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
Query: 173 KLMKKIKKLENDTISKQLTLEQ-------LRREK-IDLENTLEQEQEALVNRLWKRMDKL 224
+ + ++ E + +QL EQ LRRE+ + E L +EQ+ + +R +L
Sbjct: 361 EQQLR-REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 225 EAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQL--- 281
E+++ +E+ ++ + + R + E ER +++ R QL
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD 479
Query: 282 QHSEKMAQYLE-EERHMREENLRLQRKLQREMERREALCRQLSESESSLE 330
Q E+ ++L+ EE RE+ R +++L+RE E R + E E L+
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529
Score = 65.5 bits (158), Expect = 1e-10
Identities = 74/316 (23%), Positives = 150/316 (47%), Gaps = 32/316 (10%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRD--LRKASVTIQARAEQEEEFI 112
R E+ R L++E ++ + + + + + Q+ R+ LR+ Q R EQEEE
Sbjct: 378 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ---QLRREQEEERH 434
Query: 113 S--NTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAE--------LEQH 162
+ ++ Q L++E+E ++EEE +E R+ QL+ ++ E LE+
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494
Query: 163 LEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMD 222
+EQ+ + + +++ ++ + K+ E+ ++++ E L +EQE +L KR +
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Query: 223 --KLEAE------KRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKK 274
+LE E KR +E+ DQ + R ++ + E + + ++ + EVERL++
Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK--REEVERLEQ 612
Query: 275 QLRAAQL-----QHSEKMAQYL--EEERHMREENLRLQRKLQREMERREALCRQLSESES 327
+ R Q E+ Q L EE+ R++ LR +++ +RE + + E
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Query: 328 SLEMDDERYFNEMSAQ 343
E ++ER E++ +
Sbjct: 673 KREHEEERREQELAEE 688
Score = 65.5 bits (158), Expect = 1e-10
Identities = 75/329 (22%), Positives = 146/329 (44%), Gaps = 38/329 (11%)
Query: 54 FRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFIS 113
FR EE ++ ++E K L+ E + + + + +EE + L++ R E++ +F+
Sbjct: 1432 FREEE--QQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLE 1489
Query: 114 NTL-FKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVN 172
++ + +K +E + E E +FL E Q Q + + EQ L +++ Q
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549
Query: 173 KLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQE--------------------QEA 212
+ + K E + + ++ +QL R++ D + LE++ QE
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609
Query: 213 LVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPR-----DISMEIDSPENMMRHIRFLK- 266
+R K ++++LQE+ +Q + R + + E +RH R K
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669
Query: 267 NEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREME-RREALCRQLSES 325
E E+L ++ QL+ E+ ++ EEE+ +R + R ++ LQ E + RR+ L R+ E
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE-RERKFLQEEQQLRRQELERKFREE 1728
Query: 326 ESSLEMDD-------ERYFNEMSAQGLRP 347
E + + ERY + + LRP
Sbjct: 1729 EQLRQETEQEQLRRQERYRKILEEEQLRP 1757
Score = 63.5 bits (153), Expect = 4e-10
Identities = 65/292 (22%), Positives = 132/292 (45%), Gaps = 17/292 (5%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
R ++L LQ++ + + + + K + EE R R+ ++ + +++
Sbjct: 845 RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904
Query: 115 TLFKKIQALQKEKETLAVNYEKEEEFLTNE-LSRKLMQLQHEKAELEQHLEQEQEFQVN- 172
L ++ + LQ+E+ E+E ++ E L ++ QL E+ E + E+E++++ +
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDK 964
Query: 173 KLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRI-- 230
KL +K ++L + K+ Q R +K E L+QE+E L+ ++ + E E++
Sbjct: 965 KLQQKEEQLLGEEPEKR--RRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
Query: 231 ---LQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKM 287
LQ++ +Q + R + E R L+ E E+L + R + + +
Sbjct: 1023 KDELQQEEEQLLREEREKR----RLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 288 AQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNE 339
EEE EE L + +R + RE CR+ E L+ ++E+ E
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCRE----EEELQQEEEQLLRE 1126
Score = 63.2 bits (152), Expect = 5e-10
Identities = 79/315 (25%), Positives = 139/315 (44%), Gaps = 36/315 (11%)
Query: 63 LASLQQENKVLKIELETYKLKC--KALQEENRDLRKASVTIQARAEQEEEFISNTLFKKI 120
L S + E K L+ E + ++ + K LQEE + LR+ Q R +++ +F
Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ-LRRQERGQQRRQDRDRKFREEE----- 1561
Query: 121 QALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKK 180
Q Q+ +E E++ +F E + + + + E EQ L +++ Q + + K
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Query: 181 LENDTISKQLTLEQLRREKIDLENTLEQE-----QEALVNRLWKRMDKLEAEKRILQEKL 235
E++ + ++ +QL R++ D LE+E QE R K E+++LQE
Sbjct: 1622 REDEQLLQEREEQQLHRQERD-RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE 1680
Query: 236 DQPVSAPPSPRDISMEIDSPENMMRHIRFLK--------------NEVERLKKQLRAAQL 281
+Q + R E R +FL+ E E+L+++ QL
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Query: 282 QHSEKMAQYLEEER---HMREENLRLQ---RKLQREME-RREALCRQLSESESSLEM-DD 333
+ E+ + LEEE+ E+ LR Q RK + E + R+E +QL ES + ++
Sbjct: 1741 RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800
Query: 334 ERYFNEMSAQGLRPR 348
E+ E Q LRP+
Sbjct: 1801 EQLRQEREEQQLRPQ 1815
Score = 60.8 bits (146), Expect = 3e-09
Identities = 71/302 (23%), Positives = 129/302 (42%), Gaps = 56/302 (18%)
Query: 58 ELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLF 117
E RL + +V ++E E + + +E + R+ + + + E+ ++
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ------- 645
Query: 118 KKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHL-EQEQEFQVNKLMK 176
+++ Q+E+ + E+EEE L L R +HE+ EQ L E+EQE ++
Sbjct: 646 -QLRREQQERREQRLKREEEEERLEQRLKR-----EHEEERREQELAEEEQEQARERIKS 699
Query: 177 KIKK----LENDTISKQLTLEQLRREKIDLENTLEQEQEALVNR---LWKRMDKLEAEKR 229
+I K LE++ ++Q + R++ EQE++ W+ ++ +++
Sbjct: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQ 759
Query: 230 ILQEKLD---------------QPVSA-PPSPRDISMEIDSPENMMRHIRFLKNEVERLK 273
+++ D Q +SA PP ++ + E R RFL E E
Sbjct: 760 EEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE--- 816
Query: 274 KQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDD 333
K+ R Q + EK Q+LEEE +++RRE +QL E E L+ D
Sbjct: 817 KEQRRRQRREREKELQFLEEE---------------EQLQRRER-AQQLQEEEDGLQEDQ 860
Query: 334 ER 335
ER
Sbjct: 861 ER 862
Score = 60.1 bits (144), Expect = 4e-09
Identities = 60/256 (23%), Positives = 124/256 (48%), Gaps = 11/256 (4%)
Query: 78 ETYKLKCKALQEENRDLRKASVTI-QARAEQEEEFISNTLFKKIQALQKEKETLAVNYEK 136
E +L+ K +E+ + R+ + Q E+E L K+ + LQ+E+ ++
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 137 EEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLR 196
EEE L ++L + + E+ + +Q L +EQ+ + K ++ ++ + + +Q EQ
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLR-RKQEEERREQQEERREQQERREQQE 332
Query: 197 REKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSP- 255
+ E L +EQE + +R + E ++ L+ + ++ R+ + +
Sbjct: 333 ERR---EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 256 --ENMMRHIRFLKNEVE-RLKKQL-RAAQLQHSEKMAQYLEEERH-MREENLRLQRKLQR 310
E +R + L+ E + R ++QL R QL+ +++ + EEERH + E R +++L+R
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Query: 311 EMERREALCRQLSESE 326
E E R ++ E+E
Sbjct: 450 EQEERRDWLKREEETE 465
Score = 60.1 bits (144), Expect = 4e-09
Identities = 69/287 (24%), Positives = 133/287 (46%), Gaps = 29/287 (10%)
Query: 57 EELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTL 116
E +L +++ K L+ E + + + + +RD RK Q E EE+ +
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD-RKFREEEQLLQEGEEQQLRRQ- 1687
Query: 117 FKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMK 176
++ + ++E++ L E+E +FL E + +L+ + E EQ ++ ++ Q+ + +
Sbjct: 1688 -ERDRKFREEEQQLR-RQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER 1745
Query: 177 KIKKLENDTISKQLTLEQLRREKIDL----ENTLEQEQEALVNRLWKRMDKLEAEKRILQ 232
K LE + + + +QLRR++ D E L QE+E R + K E+++ Q
Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQ 1805
Query: 233 EKLDQPVSAPPSPRD-------ISMEIDSPENMMRHIRFLKNEVE-----RLKKQLRAAQ 280
E+ +Q + P RD ++++ E +R R + E + K + +
Sbjct: 1806 EREEQQLR--PQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863
Query: 281 LQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESES 327
L E+ + E ER +REE++R Q Q+E +R RQ+ E +S
Sbjct: 1864 LWQEEEQKRRQERERKLREEHIRRQ---QKEEQRH----RQVGEIKS 1903
Score = 58.5 bits (140), Expect = 1e-08
Identities = 69/304 (22%), Positives = 134/304 (44%), Gaps = 42/304 (13%)
Query: 67 QQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKE 126
Q+ + + E E + + + L+EE R+ + Q R E+E + L ++ Q +K
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQ--EKR 1191
Query: 127 KETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTI 186
++ Y +EEE L + ++ + + ++++L+ E E+E V K EN+
Sbjct: 1192 RQERERQYREEEE-LQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
Query: 187 SKQLTLEQLR--REKIDLENTLEQEQEA---LVNRLWKRMD------------------- 222
+QL QLR + + DL++ L ++QE R W++ D
Sbjct: 1251 -RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR 1309
Query: 223 ---KLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAA 279
K + EK++L+E+ ++ + R E E +++ + ++ R
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFREE----EQLLQEREEQPLRRQERDRKFREE 1365
Query: 280 QLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNE 339
+L+H E+ ++LEEE+ +R + R ++ L+ E + R E E L D +R F E
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQE-RERKFLKEEQQLR------CQEREQQLRQDRDRKFRE 1418
Query: 340 MSAQ 343
Q
Sbjct: 1419 EEQQ 1422
Score = 57.4 bits (137), Expect = 3e-08
Identities = 67/288 (23%), Positives = 125/288 (43%), Gaps = 44/288 (15%)
Query: 57 EELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTL 116
EE R +QE + E E K + L++ +R R + Q + QE E
Sbjct: 131 EEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQERE------ 184
Query: 117 FKKIQALQKEKETLAVNYEKEEEFLTNELSRK--LMQLQHEKAELEQHLEQEQEFQVNK- 173
+ +E++ + + EEF E R+ L++L+ + E +Q +E++ +V +
Sbjct: 185 ----ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE 240
Query: 174 ------------LMKKIKKLENDTISKQLTLEQ-------LRREKIDLENTLEQEQEALV 214
L K+ +KL+ + +Q L++ L R+++ E E++Q+ +
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 215 NRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKK 274
R + K E E+R QE+ R E + R + + + ER ++
Sbjct: 301 RREQQLRRKQEEERREQQEE-----------RREQQERREQQEERREQQLRREQEERREQ 349
Query: 275 QLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREME-RREALCRQ 321
QLR Q + + E+E RE+ LR +++L+RE + RRE R+
Sbjct: 350 QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR 397
Score = 55.8 bits (133), Expect = 8e-08
Identities = 71/278 (25%), Positives = 124/278 (44%), Gaps = 34/278 (12%)
Query: 67 QQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKE 126
Q+E ++L+ E E + QE R RK Q +EE+ + K+ + +++
Sbjct: 938 QEEEQLLREEREK-----RRRQERERQYRKDKKLQQ----KEEQLLGEEPEKRRRQEREK 988
Query: 127 KETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTI 186
K ++EEE L E K + + E+ ++ Q++E Q+ + ++ ++L
Sbjct: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRL----- 1043
Query: 187 SKQLTLEQLRREKIDLENTLEQEQEALV--NRLWKRMDKLEAEKR---ILQEKLDQPVSA 241
Q R + E L+QE+E L+ R +R +LE + R LQ++ +Q +
Sbjct: 1044 -------QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLRE 1096
Query: 242 PPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREEN 301
P R E R L+ E E+L ++ R + + E QY EEE +EE
Sbjct: 1097 EPEKR----RRQERERQCREEEELQQEEEQLLREEREKR-RRQELERQYREEEEVQQEEE 1151
Query: 302 LRLQRKLQREMERREALCRQLSESESSLEMDDERYFNE 339
L+ + E RR+ L RQ E E L+ ++E+ E
Sbjct: 1152 QLLRE--EPEKRRRQELERQYRE-EEELQQEEEQLLRE 1186
Score = 54.3 bits (129), Expect = 2e-07
Identities = 64/286 (22%), Positives = 125/286 (43%), Gaps = 51/286 (17%)
Query: 67 QQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKE 126
Q+E ++L+ E E + LQE R R+ + + E+E+ ++ Q L+++
Sbjct: 1028 QEEEQLLREEREK-----RRLQERERQYREEE---ELQQEEEQLLGEERETRRRQELERQ 1079
Query: 127 KETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTI 186
++EE+ L E ++ Q + + E+ L+QE+E + + +K ++ E
Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE---- 1135
Query: 187 SKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPR 246
LE+ RE E ++QE+E L+ E EKR QE
Sbjct: 1136 -----LERQYRE----EEEVQQEEEQLLRE--------EPEKRRRQE------------- 1165
Query: 247 DISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQR 306
+ + E + + L E + ++Q R Q + E++ + ++R+ R+E+ R
Sbjct: 1166 -LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRY-RDEDQRSDL 1223
Query: 307 KLQREMERREAL------CRQLSESESSLEMDDERYFNEMSAQGLR 346
K Q E E+ A+ C+ E+E +++D + + S Q L+
Sbjct: 1224 KWQWEPEKENAVRDNKVYCKG-RENEQFRQLEDSQLRDRQSQQDLQ 1268
Score = 53.9 bits (128), Expect = 3e-07
Identities = 71/315 (22%), Positives = 137/315 (43%), Gaps = 37/315 (11%)
Query: 55 RLEELTNRLASLQQEN-------KVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQ 107
RLE+ R L++E ++LK E E + + + L+ E ++ R+ + + E+
Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSE-EQEERRQQQLRREQQERREQRL----KREE 663
Query: 108 EEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHE------------ 155
EEE + L ++ + ++E+E E+ E + + + + QL+ E
Sbjct: 664 EEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRP 723
Query: 156 KAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVN 215
+ + Q QEQE + + +++ E + +Q E+ RR+ + E++ E
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD-FTWQWQAEEKSERGRQ 782
Query: 216 RLWKRMDKLEAEKRIL--QEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLK 273
RL R E +R L +E+ + P + + ++FL+ E E+L+
Sbjct: 783 RLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE-EQLQ 841
Query: 274 KQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERRE---------ALCRQLSE 324
++ RA QLQ E Q +E R +E+ + + Q E ER+ AL QL +
Sbjct: 842 RRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901
Query: 325 SESSLEMDDERYFNE 339
+ L+ ++E E
Sbjct: 902 EQQLLQEEEEELQRE 916
Score = 49.3 bits (116), Expect = 8e-06
Identities = 62/290 (21%), Positives = 127/290 (43%), Gaps = 32/290 (11%)
Query: 54 FRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFIS 113
FR EEL ++ +Q K L+ E + L+ + R+ + Q R ++ E+ +
Sbjct: 1362 FREEELRHQ----EQGRKFLEEE--------QRLRRQERERKFLKEEQQLRCQEREQQLR 1409
Query: 114 NTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNK 173
+K +E+E E++ +F E + + + + E EQ L QE+ ++
Sbjct: 1410 QDRDRKF----REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER----HR 1461
Query: 174 LMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQE 233
++ ++L + +QL ++ R+ ++ E L +++ R + + E E++ L+E
Sbjct: 1462 KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFR-EQELRSQEPERKFLEE 1520
Query: 234 KLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEE 293
+Q + R E + + R R + +R +K QL+ + Q +
Sbjct: 1521 --EQQLHRQQRQRKFLQE---EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ 1575
Query: 294 ER----HMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNE 339
ER + E+ +R Q + ++ ME + L RQ E + L + +R F E
Sbjct: 1576 ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ--EGQQQLRQERDRKFRE 1623
Score = 48.9 bits (115), Expect = 1e-05
Identities = 74/297 (24%), Positives = 136/297 (45%), Gaps = 41/297 (13%)
Query: 66 LQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAE----QEEEFISNTLFKKIQ 121
LQ+ + + E E + + + L EE R+ + Q R E QEEE + +K +
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 122 ALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKA---ELEQHLEQEQEFQVNK---LM 175
++E++ +EEE L E +L++ + EK ELE+ +E+E Q + L
Sbjct: 1103 RQERERQC------REEEELQQE-EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 176 KKIKKLENDTISKQL-TLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEK 234
++ +K + +Q E+L++E+ E L +EQE R +R + E+ + ++K
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEE---EQLLREEQE---KRRQERERQYREEEELQRQK 1209
Query: 235 LDQPVSAPPSPRDISMEID-SPENMMRHIR-FLKNEVERLKKQLRAAQL--QHSEKMAQY 290
Q D+ + + EN +R + + K +QL +QL + S++ Q+
Sbjct: 1210 RKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH 1269
Query: 291 L---EEERHMREENLRLQRK---------LQREMERREALCRQLSESESSLEMDDER 335
L ++ER +E R Q++ L+RE E++EA R E + +ER
Sbjct: 1270 LLGEQQERDREQERRRWQQRDRHFPEEEQLERE-EQKEAKRRDRKSQEEKQLLREER 1325
Score = 45.1 bits (105), Expect = 1e-04
Identities = 66/283 (23%), Positives = 121/283 (42%), Gaps = 42/283 (14%)
Query: 74 KIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVN 133
++E E + + + QE+ R+L + + ++E++E ++ + L ++++
Sbjct: 128 QLEEEPGQRRRQKRQEQERELAEG----EEQSEKQERLEQRDRQRRDEELWRQRQEWQ-- 181
Query: 134 YEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLE 193
E+EE E QLQ K + E++ + +L++ +K + +
Sbjct: 182 -EREERRAEEE------QLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK-------Q 227
Query: 194 QLRREKIDLENTLEQEQEALVNRLW-KRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEI 252
Q RRE+ D E+E+E W KR L E+ LQE+ P R++ E
Sbjct: 228 QQRRERQDRVFQEEEEKE------WRKRETVLRKEEEKLQEE------EPQRQRELQEEE 275
Query: 253 DSPENMMRH-IRFLKNEVERLKKQLRAAQL----QHSEKMAQYLE----EERHMREENLR 303
+ + R +R + E E+ +++LR Q Q E+ Q E +ER ++E R
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335
Query: 304 LQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLR 346
Q+ + + ERRE R+ E E + E Q LR
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Score = 39.3 bits (90), Expect = 0.008
Identities = 56/224 (25%), Positives = 93/224 (41%), Gaps = 32/224 (14%)
Query: 127 KETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTI 186
KE+L + +EE+ + QL+ E + + QEQE ++ + ++ +K E
Sbjct: 106 KESLLQDRRQEED--QRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQER--- 160
Query: 187 SKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPR 246
LEQ R++ D E Q QE W+ ++ AE+ LQ P
Sbjct: 161 -----LEQRDRQRRD-EELWRQRQE------WQEREERRAEEEQLQSCKGHETEEFPDEE 208
Query: 247 DISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQ----YLEEERHMREENL 302
+ + R R K + +R ++Q R Q + ++ + +EE ++EE
Sbjct: 209 QLRRR--ELLELRRKGREEKQQ-QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 303 RLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLR 346
+ QR+LQ E E+ L RQ E+ ER E Q LR
Sbjct: 266 QRQRELQEEEEQLRKLERQ--------ELRRERQEEEQQQQRLR 301
Score = 32.0 bits (71), Expect = 1.3
Identities = 31/126 (24%), Positives = 54/126 (42%), Gaps = 10/126 (7%)
Query: 223 KLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQ 282
+ + ++ +LQ++ + PRD +E + P R R + +++L + Q
Sbjct: 102 RCDGKESLLQDRRQEEDQRRFEPRDRQLE-EEPGQRRRQKR------QEQERELAEGEEQ 154
Query: 283 HSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLS--ESESSLEMDDERYFNEM 340
SEK + + +R R+E L QR+ +E E R A QL + + E DE
Sbjct: 155 -SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR 213
Query: 341 SAQGLR 346
LR
Sbjct: 214 ELLELR 219
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 69.7 bits (169), Expect = 5e-12
Identities = 73/277 (26%), Positives = 136/277 (49%), Gaps = 20/277 (7%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKC---KALQEENRDLRKASVTIQARAEQEEEF 111
R EEL N L L++EN++L+ ++ K+ C +AL++EN +L + + + ++ +
Sbjct: 626 RAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELEREN----RKLKKTLDS 681
Query: 112 ISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELE-QHLEQEQEFQ 170
N F ++++L+KE L E+ E N S K ++ + +LE + LE E+E Q
Sbjct: 682 FKNLTF-QLESLEKENSQLD---EENLELRRNVESLKCASMKMAQLQLENKELESEKE-Q 736
Query: 171 VNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRI 230
+ K ++ +K T +++ + L E L+ TLE + + +L + LE E +
Sbjct: 737 LKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKK-IQQLESELQDLEMENQT 795
Query: 231 LQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQY 290
LQ+ L++ + + E S E + K ++E+ K+LR Q +E
Sbjct: 796 LQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR----QQAEIKDTT 851
Query: 291 LEEERHMREENLRLQRK-LQREMERREALCRQLSESE 326
L EE +++ NL + K L +E+ + C +L E E
Sbjct: 852 L-EENNVKIGNLEKENKTLSKEIGIYKESCVRLKELE 887
Score = 69.3 bits (168), Expect = 7e-12
Identities = 90/322 (27%), Positives = 145/322 (45%), Gaps = 67/322 (20%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKC---KALQEENRDL-RKASVTIQARAEQEEEF 111
LEE ++ +L++ENK L E+ YK C K L++EN++L ++A++ I+ E+
Sbjct: 852 LEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDL 911
Query: 112 ISNTLFKKIQALQKEKETLAVNYEK----EEEFLTNELSR----KLMQLQHEKAELEQHL 163
+S L K Q + + E L EK +E L +E S KL++ ++LE L
Sbjct: 912 VSEKL--KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLE-----SKLESTL 964
Query: 164 EQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDK 223
++ E + K+ +LE T Q QLR+E T+++ EAL R
Sbjct: 965 KKSLEIKEEKIAALEARLEESTNYNQ----QLRQEL----KTVKKNYEALKQR------- 1009
Query: 224 LEAEKRILQEKLDQPVSAPPSPRDISMEIDSPE-------------NMMRHIRFLKNEVE 270
+ E+R++Q S P S D E +S E + R+ L+ E +
Sbjct: 1010 -QDEERMVQS------SPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQ 1062
Query: 271 RLKKQLRAAQLQHSEKMAQYLEEERH---MREENLRLQ---RKLQREMERREALC----- 319
LK QL+ + Q++ AQ L +R ++E+N LQ KLQ E +
Sbjct: 1063 ALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMN 1122
Query: 320 --RQLSESESSLEMDDERYFNE 339
QL +SSLE ++E E
Sbjct: 1123 QNAQLLIQQSSLENENESVIKE 1144
Score = 63.2 bits (152), Expect = 5e-10
Identities = 60/275 (21%), Positives = 135/275 (49%), Gaps = 36/275 (13%)
Query: 62 RLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFIS--NTLFKK 119
R+ +++ENK+L ++ K ++ E R ++K + + E+ EE + + L K+
Sbjct: 581 RVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE 640
Query: 120 IQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLE--QEQEFQVNKLMKK 177
+ LQK+ L + EK E L ++ +L+ E +L++ L+ + FQ+ L K+
Sbjct: 641 NELLQKKITNLKITCEKIE-----ALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Query: 178 IKKLENDTISKQLTLEQL-----RREKIDLEN-TLEQEQEALVNRL------WKRMDKLE 225
+L+ + + + +E L + ++ LEN LE E+E L L +K+ ++LE
Sbjct: 696 NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLE 755
Query: 226 A-------EKRILQEKLDQP----VSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKK 274
E + LQ+ L+ +D+ ME + + + ++ +E+L+K
Sbjct: 756 VSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEK 815
Query: 275 QLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQ 309
+ ++ + ++ +Q ++++ + +EN RL+++ +
Sbjct: 816 ENKSLE----QETSQLEKDKKQLEKENKRLRQQAE 846
Score = 59.7 bits (143), Expect = 6e-09
Identities = 84/342 (24%), Positives = 142/342 (41%), Gaps = 55/342 (16%)
Query: 54 FRLEELTNRLASLQQENKVLKIELETYK---LKCKALQEENRDLR-------------KA 97
F+LE L + L +EN L+ +E+ K +K LQ EN++L KA
Sbjct: 687 FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKA 746
Query: 98 SVTIQARAEQ-------EEEFISNTL---FKKIQALQKEKETLAVNYEKEEEFLTNEL-- 145
S R E E + + TL KKIQ L+ E + L E E + L L
Sbjct: 747 SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDL----EMENQTLQKNLEE 802
Query: 146 ----SRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQ--LRREK 199
S++L QL+ E LEQ Q E +L K+ K+L K TLE+ ++
Sbjct: 803 LKISSKRLEQLEKENKSLEQETSQ-LEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN 861
Query: 200 IDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPR-DISMEIDSPENM 258
++ EN ++ + R+ +LE E + L ++ + + R D+ E + M
Sbjct: 862 LEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM 921
Query: 259 MRHIRFLKNEVERLKKQLRAAQLQHSE------------KMAQYLEEERHMREENL-RLQ 305
+ L +E+E++ L +L H E K+ L++ ++EE + L+
Sbjct: 922 NNDLEKLTHELEKI--GLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALE 979
Query: 306 RKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRP 347
+L+ + L ++L + + E +R E Q P
Sbjct: 980 ARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPP 1021
Score = 52.0 bits (123), Expect = 1e-06
Identities = 71/314 (22%), Positives = 144/314 (45%), Gaps = 50/314 (15%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRD-----------------LRKAS 98
LEE T +L +QE + ++IEL K LQ+EN + LR+ +
Sbjct: 267 LEEKTEQLLDCKQELEQMEIEL-------KRLQQENMNLLSDARSARMYRDELDALREKA 319
Query: 99 VTI---QARAEQEEEFISNTLFKK--IQALQKEKETLAVNYEKEEEFL--TNELSRKLMQ 151
V + ++ + +E + + F K ++ L+++ + L E+ L T S KL +
Sbjct: 320 VRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379
Query: 152 LQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQ--- 208
L+ E +L+ L + E + + KKI++L + ++ ++ +Q E + L LEQ
Sbjct: 380 LEKENLQLKAKL-HDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISR 438
Query: 209 ---EQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFL 265
EA L +++L + + + E +Q S + ++ +DS E I +
Sbjct: 439 TSELSEAPQKSLGHEVNELTSSRLLKLEMENQ--SLTKTVEELRTTVDSVEGNASKILKM 496
Query: 266 KNEVERLKKQLRAAQ---------LQHSEKMAQYLEEERHMREENLR-LQRKLQREMERR 315
+ E +RL K++ + LQ+ + +++ L +E+ E+ + L+ +R+++
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 556
Query: 316 EALCRQLSESESSL 329
E L+++ SSL
Sbjct: 557 EQENEHLNQTVSSL 570
Score = 49.7 bits (117), Expect = 6e-06
Identities = 61/287 (21%), Positives = 112/287 (39%), Gaps = 37/287 (12%)
Query: 56 LEELTN-RLASLQQENKVLKIELETYKL----------KCKALQEENRDLRKASVTIQAR 104
+ ELT+ RL L+ EN+ L +E + K +++EN+ L K ++
Sbjct: 454 VNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENE 513
Query: 105 AEQEEEFISNT-------------LFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQ 151
QE++ + N L K I+ L++ E E+E E L +S
Sbjct: 514 IVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVS----- 568
Query: 152 LQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLE--QE 209
L Q + E +V + K+ K L L ++ EK ++ LE +E
Sbjct: 569 ------SLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKE 622
Query: 210 QEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEV 269
+ L + LE E +LQ+K+ + E E R ++ +
Sbjct: 623 KGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSF 682
Query: 270 ERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERRE 316
+ L QL + + ++S+ + LE R++ + Q ++E +E
Sbjct: 683 KNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKE 729
Score = 48.5 bits (114), Expect = 1e-05
Identities = 69/318 (21%), Positives = 135/318 (42%), Gaps = 73/318 (22%)
Query: 62 RLASLQQENKVL---KIELETYKLKCKALQEENRDLRKASVTIQARA-----------EQ 107
R+ L+++N+VL K LE +A ++ +L K ++ ++A+ ++
Sbjct: 345 RVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKK 404
Query: 108 EEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSR----------------KLMQ 151
EE + + ++ Q E+L + +E E+ T+ELS +L++
Sbjct: 405 IEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLK 464
Query: 152 LQHEKAELEQHLEQ----------------EQEFQVNKLMKKIKKLENDTISKQLTLEQ- 194
L+ E L + +E+ + E + +L KK++ LEN+ + ++ +L+
Sbjct: 465 LEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNC 524
Query: 195 ------LRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDI 248
L +EK LE T+E +E +++ LE E E L+Q VS+ I
Sbjct: 525 QNLSKDLMKEKAQLEKTIETLRE----NSERQIKILEQEN----EHLNQTVSSLRQRSQI 576
Query: 249 SMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKL 308
S E ++E+ K L + + S K+++ E+R +++E + K
Sbjct: 577 SAEARV------------KDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG 624
Query: 309 QREMERREALCRQLSESE 326
+R E L E+E
Sbjct: 625 ERAEELENELHHLEKENE 642
Score = 47.4 bits (111), Expect = 3e-05
Identities = 71/303 (23%), Positives = 129/303 (42%), Gaps = 42/303 (13%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQ----------EENRDLRKASVTIQAR 104
RLEE TN L+QE K +K E K + + E+N+ R++ T +
Sbjct: 981 RLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTREL 1040
Query: 105 AEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLE 164
+ ++ I + + LQ EK+ L K+ E N L +++ LQ + L
Sbjct: 1041 LKVKDRLIE--VERNNATLQAEKQALKTQL-KQLETQNNNLQAQILALQRQTVSL----- 1092
Query: 165 QEQEFQVNKLMKKIKKLENDTISKQLT-LEQLRREKIDLENTLEQEQEALVNR------L 217
QEQ + K+ ++EN T++ Q T L + + +++LE E E+++ L
Sbjct: 1093 QEQNTTLQTQNAKL-QVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSL 1151
Query: 218 WKRMDKLEAEKRILQEK--------LDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEV 269
+ + K + +L E+ + + + + +++ +E E+ + K ++
Sbjct: 1152 YDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQL 1211
Query: 270 ERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSL 329
E L+K L+ Q EKM LE + H E +KL E +R QL + L
Sbjct: 1212 EDLEKMLKVEQ----EKM--LLENKNH--ETVAAEYKKLCGENDRLNHTYSQLLKETEVL 1263
Query: 330 EMD 332
+ D
Sbjct: 1264 QTD 1266
Score = 40.0 bits (92), Expect = 0.005
Identities = 48/217 (22%), Positives = 96/217 (44%), Gaps = 35/217 (16%)
Query: 175 MKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEK 234
MK+ + ++ ++ ++RR + +LE EQ + + ++++E E + LQ++
Sbjct: 240 MKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCK-----QELEQMEIELKRLQQE 294
Query: 235 LDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLR-----AAQLQHSEKMAQ 289
+S S R E+D+ + L++EV R K++L A+++ ++ Q
Sbjct: 295 NMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQ 354
Query: 290 YLEEERHMRE------------------ENLRLQRKL-----QREMERREALCRQLSESE 326
L E + M E ENL+L+ KL +R+M+R++ +L E
Sbjct: 355 VLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKK--IEELMEEN 412
Query: 327 SSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSS 363
+LEM ++ +E G +S + +P S
Sbjct: 413 MTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKS 449
Score = 35.0 bits (79), Expect = 0.15
Identities = 46/186 (24%), Positives = 79/186 (42%), Gaps = 24/186 (12%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
R +L + L+ K+LK+E E L+ K + + +K E + +++
Sbjct: 1200 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLC--------GENDRLNH 1251
Query: 115 TLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKL 174
T + L KE E L +++ + L N KL Q + E AE + EQ Q+ +
Sbjct: 1252 TYSQ----LLKETEVLQTDHKNLKSLLNNS---KLEQTRLE-AEFSKLKEQYQQLDITST 1303
Query: 175 MKKIKKLENDT-ISKQL--TLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRIL 231
KL N + QL LE+ R +D TL + L+ + + D E+R
Sbjct: 1304 -----KLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQY 1358
Query: 232 QEKLDQ 237
+KL++
Sbjct: 1359 IDKLNE 1364
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 69.3 bits (168), Expect = 7e-12
Identities = 81/307 (26%), Positives = 142/307 (46%), Gaps = 33/307 (10%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQE-------ENRDLRKASVTIQARAEQ 107
RL E+ + L E L+ +L+ C +E + ++L + ++AR E+
Sbjct: 867 RLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEE 926
Query: 108 EEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQ 167
EEE + Q LQ EK+ + N ++ EE L E S + +LQ EK E L++ +
Sbjct: 927 EEE--------RCQHLQAEKKKMQQNIQELEEQLEEEESAR-QKLQLEKVTTEAKLKKLE 977
Query: 168 EFQV-----NKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMD 222
E Q+ N + K KKL D I++ T EK L+ + EA++ L +R+
Sbjct: 978 EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLR 1037
Query: 223 KLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQ 282
+ E +++ L EK + + + D+S D + I LK ++ + +++L+AA +
Sbjct: 1038 REEKQRQEL-EKTRRKLEGDST--DLS---DQIAELQAQIAELKMQLAKKEEELQAALAR 1091
Query: 283 HSEKMAQ---YLEEERHMREENLRLQRKLQREMERR---EALCRQLSESESSLEMDDERY 336
E+ AQ L++ R + + LQ L+ E R E R L E +L+ + E
Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 1151
Query: 337 FNEMSAQ 343
+ +AQ
Sbjct: 1152 LDSTAAQ 1158
Score = 61.6 bits (148), Expect = 1e-09
Identities = 71/298 (23%), Positives = 135/298 (45%), Gaps = 43/298 (14%)
Query: 58 ELTNRLASLQQ-----ENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAE------ 106
EL N + L Q E+K K+E + +L+ K + E A + + E
Sbjct: 1228 ELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTG 1287
Query: 107 --QEEEFISNTLFKKIQALQKE-KETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHL 163
+ + S+ L K AL+ + ++T + E+ + L+ LS KL Q++ EK + L
Sbjct: 1288 LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLS--LSTKLKQVEDEKNSFREQL 1345
Query: 164 EQEQEFQVNKLMKKI----------KKLENDTISKQLTLEQLRRE-KIDLENTLEQEQEA 212
E+E+E + N L K+I KK D++ T E+++R+ + DLE ++ +E
Sbjct: 1346 EEEEEAKHN-LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEK 1404
Query: 213 LVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERL 272
+ DKLE K LQ++LD D+ +++D ++ + + ++L
Sbjct: 1405 VA-----AYDKLEKTKTRLQQELD----------DLLVDLDHQRQSACNLEKKQKKFDQL 1449
Query: 273 KKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLE 330
+ + +++E+ + E R + L L R L+ ME++ L R + + +E
Sbjct: 1450 LAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEME 1507
Score = 52.8 bits (125), Expect = 7e-07
Identities = 63/278 (22%), Positives = 134/278 (48%), Gaps = 35/278 (12%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
++ EL ++++ LQ++ LE+ + +++ RDL + ++A + E+ + +
Sbjct: 1105 KIRELESQISELQED-------LESERASRNKAEKQKRDLGEE---LEALKTELEDTLDS 1154
Query: 115 TLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKA--ELEQHLEQEQEFQVN 172
T ++ ++E+E + EEE T+E + M+ +H +A EL + LEQ + + N
Sbjct: 1155 TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214
Query: 173 KLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQ 232
L K + LEN+ ++ L + K D E+ ++ EA + L + ++ E + L
Sbjct: 1215 -LEKAKQTLENERGELANEVKVLLQGKGDSEHK-RKKVEAQLQELQVKFNEGERVRTELA 1272
Query: 233 EKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRA--AQLQHSEKMAQY 290
+K+ + + +E+D+ ++ ++ +L K A +QLQ ++++ Q
Sbjct: 1273 DKVTK----------LQVELDNVTGLLSQ---SDSKSSKLTKDFSALESQLQDTQELLQ- 1318
Query: 291 LEEERHMREENLRLQRKLQREMERREALCRQLSESESS 328
EE R + L L KL++ + + + QL E E +
Sbjct: 1319 -EENR----QKLSLSTKLKQVEDEKNSFREQLEEEEEA 1351
Score = 52.0 bits (123), Expect = 1e-06
Identities = 67/307 (21%), Positives = 137/307 (44%), Gaps = 36/307 (11%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN- 114
L+E + SL + K ++ E +++ + + +E +L K T+ A+ ++ + +
Sbjct: 1317 LQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDS 1376
Query: 115 -----TLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEF 169
T + + LQK+ E L+ +E E+ ++L + +LQ E +L L+ +++
Sbjct: 1377 VGCLETAEEVKRKLQKDLEGLSQRHE-EKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS 1435
Query: 170 QVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKR 229
N L KK KK + ++++ T+ E+ D +E+E K + R
Sbjct: 1436 ACN-LEKKQKKFDQ-LLAEEKTISAKYAEERDRAEAEAREKET----------KALSLAR 1483
Query: 230 ILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLR------AAQLQH 283
L+E ++Q + E++ + + +E+E+ K+ L QL+
Sbjct: 1484 ALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEE 1543
Query: 284 SEKMAQYLEEERHMREENLR---------LQRKLQREMERREALCRQLSESESSLEMDDE 334
E Q E+ + E NL+ LQ + ++ E+++ L RQ+ E E+ E++DE
Sbjct: 1544 LEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEA--ELEDE 1601
Query: 335 RYFNEMS 341
R M+
Sbjct: 1602 RKQRSMA 1608
Score = 52.0 bits (123), Expect = 1e-06
Identities = 57/273 (20%), Positives = 124/273 (45%), Gaps = 23/273 (8%)
Query: 67 QQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKE 126
+ E K+ +E E +L QEE +A Q ++ + I+N+ K AL+++
Sbjct: 1670 ENEKKLKSMEAEMIQL-----QEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK 1724
Query: 127 KETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTI 186
+ A + EEE + + +L+ + +KA L Q + + +++ +N+
Sbjct: 1725 RRLEARIAQLEEELEEEQGNTELINDRLKKANL-----QIDQINTDLNLERSHAQKNENA 1779
Query: 187 SKQLTLE--QLRREKIDLENTLEQEQEALVNRLWKRM----DKLEAEKRILQEKLDQPVS 240
+QL + +L+ + ++E T++ + +A + L ++ ++L+ E + Q Q
Sbjct: 1780 RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRR 1839
Query: 241 APPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREE 300
+D+ +++D + ++ KQL+ QL+ +E+ AQ R
Sbjct: 1840 TEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLK-RQLEEAEEEAQRANASRR---- 1894
Query: 301 NLRLQRKLQREMERREALCRQLSESESSLEMDD 333
+LQR+L+ E +A+ R++S ++ L D
Sbjct: 1895 --KLQRELEDATETADAMNREVSSLKNKLRRGD 1925
Score = 50.4 bits (119), Expect = 3e-06
Identities = 54/235 (22%), Positives = 103/235 (43%), Gaps = 24/235 (10%)
Query: 118 KKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKK 177
KK L E++T++ Y +E + E K + LE+ +EQ+ E + +L K+
Sbjct: 1444 KKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE--LERLNKQ 1501
Query: 178 IKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEA-EKRILQEKLD 236
+ D +S + + + E + LEQ+ E + +L + D+L+A E L+ +++
Sbjct: 1502 FRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN 1561
Query: 237 QPVSAPPSPRDISMEIDSPE----NMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLE 292
RD+ + E ++R +R ++ E+E +KQ A + +
Sbjct: 1562 LQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKD 1621
Query: 293 EERHM------REENLRLQRKLQREME-----------RREALCRQLSESESSLE 330
E H+ R+E ++ RKLQ +M+ RE + Q E+E L+
Sbjct: 1622 LEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLK 1676
Score = 47.8 bits (112), Expect = 2e-05
Identities = 60/271 (22%), Positives = 116/271 (42%), Gaps = 53/271 (19%)
Query: 96 KASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHE 155
K +Q ++EE K+ +EK+ A N E E L ++L + +QLQ +
Sbjct: 833 KVKPLLQVSRQEEEMMAKEEELVKV----REKQLAAENRLTEMETLQSQLMAEKLQLQEQ 888
Query: 156 ---------------------KAELEQ-------HLEQEQE------FQVNKLMKKIKKL 181
K ELE+ +E+E+E + K+ + I++L
Sbjct: 889 LQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQEL 948
Query: 182 ENDTISKQLTLEQLRREKIDLENTLEQ-EQEALVNRLWKRMDKLEAEKRILQEKLDQPVS 240
E ++ ++L+ EK+ E L++ E+E ++ L + KL EK++L++++
Sbjct: 949 EEQLEEEESARQKLQLEKVTTEAKLKKLEEEQII--LEDQNCKLAKEKKLLEDRI----- 1001
Query: 241 APPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMRE- 299
+ + + E + + LKN+ E + L +L+ EK Q LE+ R E
Sbjct: 1002 -----AEFTTNLTEEEEKSKSLAKLKNKHEAMITDLE-ERLRREEKQRQELEKTRRKLEG 1055
Query: 300 ENLRLQRKLQREMERREALCRQLSESESSLE 330
++ L ++ + L QL++ E L+
Sbjct: 1056 DSTDLSDQIAELQAQIAELKMQLAKKEEELQ 1086
>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
Length = 615
Score = 68.9 bits (167), Expect = 9e-12
Identities = 110/473 (23%), Positives = 178/473 (37%), Gaps = 135/473 (28%)
Query: 58 ELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLF 117
++ RL L++EN L+ L+ Y++K + + EE S
Sbjct: 50 DIKERLGGLERENATLRRRLKVYEIKYPLISDFG----------------EEHGFSLYEI 93
Query: 118 KKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKK 177
K L+ EK +L ++L Q QHE L+++ EQE+ Q+ ++++
Sbjct: 94 KDGSLLEVEKVSL---------------QQRLNQFQHE---LQKNKEQEE--QLGEMIQ- 132
Query: 178 IKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRI---LQEK 234
E+L EK DLE L +E ALV +++ LE + R LQ+
Sbjct: 133 -------------AYEKLCVEKSDLETEL-REMRALVETHLRQICGLEQQLRQQQGLQDA 178
Query: 235 LDQPVSAPPSPRDISMEID--------------------SPENMMRHIRFLKNEVERLKK 274
+S PP+P ++D +P R L+ +E +
Sbjct: 179 AFSNLSPPPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEALEAAQG 238
Query: 275 QLRAAQLQHSEKMAQYLEEERHMRE-ENLRLQRKLQREMERREALCRQLSESESSLEMDD 333
+ R AQL+ + A+ + +++ + R Q + ER A +++ + + +L +
Sbjct: 239 EARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAY 298
Query: 334 ERYFNEM-------SAQGLRPRTV------------------SSPIPYTPSPS----SSR 364
E+ S QG RT+ SP P PSPS ++
Sbjct: 299 TELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAP 358
Query: 365 PISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSPDKFK 424
P P S PP P + S P P+R +
Sbjct: 359 PCPPCQSPVPQRRSPVPPC------------PSPQQRRSPASPSCPSPVPQR-------R 399
Query: 425 RPTPP----PSPNTQTPV-------QPPPPPPPPPMQPTVPSAATSQPTPSQH 466
P PP PSP ++PV QP PPPPPPP + T+ A ++P PS H
Sbjct: 400 SPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKP-PSHH 451
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 68.6 bits (166), Expect = 1e-11
Identities = 67/285 (23%), Positives = 131/285 (45%), Gaps = 37/285 (12%)
Query: 86 ALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTN-- 143
+++EE L++A +AR ++ EE K+ +L +EK L + + E++ L +
Sbjct: 851 SMKEEFTRLKEALEKSEARRKELEE--------KMVSLLQEKNDLQLQVQAEQDNLADAE 902
Query: 144 ----ELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIK------KLENDTISKQLTLE 193
+L + +QL+ + E+ + LE E+E KK K +L+ D +LTL
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962
Query: 194 QLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRD------ 247
++ +EK EN ++ E + L + + KL EK+ LQE Q + + D
Sbjct: 963 KVEKEKHATENKVKNLTEEMAG-LDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLT 1021
Query: 248 -----ISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENL 302
+ ++D E + + ++ ++ER K++L L+ +++ LE ++ +E L
Sbjct: 1022 KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLE-GDLKLTQESIMDLENDKQQLDERL 1080
Query: 303 RLQ----RKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQ 343
+ + L +E +AL QL + L+ E E+ A+
Sbjct: 1081 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAE 1125
Score = 56.2 bits (134), Expect = 6e-08
Identities = 77/308 (25%), Positives = 135/308 (43%), Gaps = 64/308 (20%)
Query: 55 RLEELTNRL-ASLQQENKVLKIELETYKLKC----KALQEENRDLRKASVTIQARAEQEE 109
+LE+ + L SL+QE KV +++LE K K K QE DL + R ++++
Sbjct: 1026 KLEQQVDDLEGSLEQEKKV-RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKD 1084
Query: 110 EFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQ-- 167
F N L +I+ +E+ L ++L +KL +LQ ELE+ LE E+
Sbjct: 1085 -FELNALNARIE---------------DEQALGSQLQKKLKELQARIEELEEELEAERTA 1128
Query: 168 EFQVNKLMKKIKKLENDTISKQL------TLEQLRREK----------IDLEN-TLEQEQ 210
+V KL + + E + IS++L T Q+ K DLE TL+ E
Sbjct: 1129 RAKVEKLRSDLSR-ELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEA 1187
Query: 211 EAL---------VNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRH 261
A V L +++D L+ K+ L+++ + +E+D + M
Sbjct: 1188 TAAALRKKHADSVAELGEQIDNLQRVKQKLEKE----------KSEFKLELDDVTSNMEQ 1237
Query: 262 IRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQR---KLQREMERREAL 318
I K +E++ + L +H K + + + +LQ +L R+++ +EAL
Sbjct: 1238 IIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 1297
Query: 319 CRQLSESE 326
QL+ +
Sbjct: 1298 ISQLTRGK 1305
Score = 51.6 bits (122), Expect = 2e-06
Identities = 64/292 (21%), Positives = 137/292 (46%), Gaps = 16/292 (5%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNT 115
LEE++ RL ++ +++E K + Q+ RDL +A++ +A A + +++
Sbjct: 1143 LEEISERL---EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
Query: 116 ---LFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVN 172
L ++I LQ+ K+ L + E + ++++ + Q+ KA LE+ + + E Q+N
Sbjct: 1200 VAELGEQIDNLQRVKQKLEKE-KSEFKLELDDVTSNMEQIIKAKANLEK-MCRTLEDQMN 1257
Query: 173 KLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQ 232
+ K ++ + +L+ E +L L+ E+EAL+++L + + L+
Sbjct: 1258 EHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLD-EKEALISQLTRGKLTYTQQLEDLK 1316
Query: 233 EKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQY-- 290
+L++ V A + ++ + S + +R E K +L+ + + ++AQ+
Sbjct: 1317 RQLEEEVKAKNA---LAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 291 -LEEERHMREENLR-LQRKLQREMERREALCRQLSESESSLEMDDERYFNEM 340
E + R E L ++KL + ++ E ++ SSLE R NE+
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEI 1425
Score = 50.8 bits (120), Expect = 3e-06
Identities = 67/319 (21%), Positives = 129/319 (40%), Gaps = 35/319 (10%)
Query: 55 RLEELTNRLASLQQENKVLKIEL--------------ETYKLKCKALQEENRDLRKASVT 100
+ EE + L S Q+E + L EL ET+K + K LQEE DL + +
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTE-QLG 1517
Query: 101 IQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELE 160
+ E E + L + LQ E + E EE ++ R ++ KAE+E
Sbjct: 1518 SSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE----GKILRAQLEFNQIKAEIE 1573
Query: 161 QHL---EQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEAL--VN 215
+ L ++E E ++ + L+ ++ + + R K +E L + + L N
Sbjct: 1574 RKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHAN 1633
Query: 216 RL----WKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMR----HIRFLKN 267
R+ K++ L++ + Q +LD V A ++ ++ N+++ +R +
Sbjct: 1634 RMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVE 1693
Query: 268 EVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQ---RKLQREMERREALCRQLSE 324
+ ER +K ++ SE++ + + + ++ +LQ E+E CR E
Sbjct: 1694 QTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEE 1753
Query: 325 SESSLEMDDERYFNEMSAQ 343
D E+ +
Sbjct: 1754 KAKKAITDAAMMAEELKKE 1772
Score = 48.1 bits (113), Expect = 2e-05
Identities = 61/265 (23%), Positives = 113/265 (42%), Gaps = 29/265 (10%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFIS- 113
R EEL L Q + + +E KC +L++ L+ + E+ +
Sbjct: 1382 RTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1441
Query: 114 ----NTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEF 169
F KI A K+K + + + + LS +L +L++ E +HLE +
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRE 1501
Query: 170 QVNKLMKKIKKLENDTISKQLTL-------EQLRREKIDLENTLE------QEQEALVNR 216
N L ++I L S T+ +QL EK++L++ LE + +E + R
Sbjct: 1502 NKN-LQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 1560
Query: 217 LWKRMDKLEAE-KRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQ 275
++++AE +R L EK ++ A R+ +DS + + +NE R+KK+
Sbjct: 1561 AQLEFNQIKAEIERKLAEKDEEMEQA---KRNHLRVVDSLQTSLDAETRSRNEALRVKKK 1617
Query: 276 LRA------AQLQHSEKMAQYLEEE 294
+ QL H+ +MA +++
Sbjct: 1618 MEGDLNEMEIQLSHANRMAAEAQKQ 1642
Score = 43.5 bits (101), Expect = 4e-04
Identities = 53/244 (21%), Positives = 107/244 (43%), Gaps = 25/244 (10%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNT 115
LEEL + ++ K+ + EL + + L +N L + A Q + +
Sbjct: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
Query: 116 LFKKIQALQKEKETL------AVNYEKEE------EFLTNELSRKLMQLQHEKAELEQHL 163
+ + A +K K+ + A +KE+ E + + + + LQH E EQ
Sbjct: 1745 VQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1804
Query: 164 EQEQEFQVNKLMKKIKKLENDTISKQL----TLEQLRREKIDLENTLEQEQEALVN--RL 217
+ + Q+ KL ++++LEN+ ++Q +++ +R+ + ++ Q +E N RL
Sbjct: 1805 LKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRL 1864
Query: 218 WKRMDKLE----AEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLK 273
+DKL+ A KR +E +Q + R + E+D E +++V +L+
Sbjct: 1865 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE---ERADIAESQVNKLR 1921
Query: 274 KQLR 277
+ R
Sbjct: 1922 AKSR 1925
Score = 33.1 bits (74), Expect = 0.56
Identities = 48/227 (21%), Positives = 97/227 (42%), Gaps = 24/227 (10%)
Query: 118 KKIQALQKEKETLAVNYEKEEEFLTNELS---RKLMQLQHEKAELEQHLEQEQEFQVNKL 174
K +Q+L K+ + + + + L ++ R+ LQ E EL +EQ + +
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSR---- 1699
Query: 175 MKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEK 234
K E + I ++ L + L N +++ +A +++L +++ E R +EK
Sbjct: 1700 ----KLAEQELIETSERVQLLHSQNTSLINQ-KKKMDADLSQLQTEVEEAVQECRNAEEK 1754
Query: 235 LDQPVS-APPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAA----------QLQH 283
+ ++ A ++ E D+ ++ R + ++ ++ L+ +L A QLQ
Sbjct: 1755 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQK 1814
Query: 284 SEKMAQYLEEERHMREENLRLQRKLQREMERR-EALCRQLSESESSL 329
E + LE E ++ K R+ ERR + L Q E +L
Sbjct: 1815 LEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 1861
Score = 29.6 bits (65), Expect = 6.2
Identities = 39/174 (22%), Positives = 75/174 (43%), Gaps = 27/174 (15%)
Query: 173 KLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQ 232
KL KIK L L + +E ++ + +EAL +R + E +LQ
Sbjct: 831 KLYFKIKPL--------LKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ 882
Query: 233 EKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLE 292
EK D+ +++ + ++ + +++ + K QL A + +E+ LE
Sbjct: 883 EKN-----------DLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNER----LE 927
Query: 293 EERHMREENLRLQRKLQREMERREALCRQLSESESSL-EMDDERYFNEMSAQGL 345
+E M E +RKL+ E L R + + E +L +++ E++ E + L
Sbjct: 928 DEEEMNAELTAKKRKLEDECSE---LKRDIDDLELTLAKVEKEKHATENKVKNL 978
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 68.6 bits (166), Expect = 1e-11
Identities = 71/303 (23%), Positives = 137/303 (45%), Gaps = 38/303 (12%)
Query: 58 ELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLF 117
E +A++++E + +K EL + K K L+E+ L K +Q +
Sbjct: 850 ETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQ------------- 896
Query: 118 KKIQALQKEKETLAVNYEKEEEFLTN--ELSRKLMQLQHEKAELEQHLEQEQEFQVNKLM 175
+Q E E LA E+ ++ + +L K+ ++ E+AE E+ + E + KL
Sbjct: 897 -----VQAEAEGLADAEERCDQLIKTKIQLEAKIKEVT-ERAEDEEEINAELTAKKRKLE 950
Query: 176 KKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKL 235
+ +L+ D +LTL ++ +EK EN ++ E + L + + KL EK+ LQE
Sbjct: 951 DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG-LDETIAKLTKEKKALQEAH 1009
Query: 236 DQPVSAPPSPRD-----------ISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHS 284
Q + + D + ++D E + + L+ ++ER K++L L+ +
Sbjct: 1010 QQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE-GDLKLA 1068
Query: 285 EKMAQYLEEERHMREENLRLQR----KLQREMERREALCRQLSESESSLEMDDERYFNEM 340
++ +E E+ +E L+ + LQ ++E +AL QL + L+ E E+
Sbjct: 1069 QESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEI 1128
Query: 341 SAQ 343
A+
Sbjct: 1129 EAE 1131
Score = 61.2 bits (147), Expect = 2e-09
Identities = 75/338 (22%), Positives = 156/338 (46%), Gaps = 49/338 (14%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQE------E 109
+++L LA +++E + +++ + L E L K +Q +Q E
Sbjct: 960 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE 1019
Query: 110 EFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSR--------------KLMQLQHE 155
E NTL K L+++ + L + E+E++ L +L R +M +++E
Sbjct: 1020 EDKVNTLTKAKIKLEQQVDDLEGSLEQEKK-LRMDLERAKRKLEGDLKLAQESIMDIENE 1078
Query: 156 KAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVN 215
K +L++ L+++ EF+++ L KI+ + I Q +++L+ +LE +E E+ +
Sbjct: 1079 KQQLDEKLKKK-EFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAK 1137
Query: 216 RLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQ 275
+R D L E + E+L++ A + +++ + ++ MR E L+ +
Sbjct: 1138 AEKQRSD-LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR----DLEEATLQHE 1192
Query: 276 LRAAQL--QHSEKMAQYLEEERHMREENLRLQR-KLQREME----------------RRE 316
AA L +H++ +A+ E+ +++ +L++ K + +ME E
Sbjct: 1193 ATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLE 1252
Query: 317 ALCRQLSESESSL---EMDDERYFNEMSAQGLRPRTVS 351
+CR L + S L E + +R N+++AQ R +T S
Sbjct: 1253 KMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTES 1290
Score = 60.8 bits (146), Expect = 3e-09
Identities = 73/323 (22%), Positives = 136/323 (42%), Gaps = 60/323 (18%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKC----KALQEENRDLRKASVTIQARAEQEEE 110
+LE+ + L ++ K L+++LE K K K QE D+ + + +++E
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091
Query: 111 FISNT-------------LFKKIQALQKEKETLAVNYEKEE------EFLTNELSRKLMQ 151
ISN L KKI+ LQ E L E E E ++LSR+L +
Sbjct: 1092 EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1151
Query: 152 LQHE--------KAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLE 203
+ A++E + ++E EFQ K + LE T+ + T LR++ D
Sbjct: 1152 ISERLEEAGGATSAQIEMNKKREAEFQ-----KMRRDLEEATLQHEATAATLRKKHADSV 1206
Query: 204 NTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIR 263
L ++ ++ L + KLE EK ++ MEID + + +
Sbjct: 1207 AELGEQ----IDNLQRVKQKLEKEKS-----------------EMKMEIDDLASNVETVS 1245
Query: 264 FLKNEVERLKKQL--RAAQLQHSEKMAQYLEEERHMREENLRLQR-KLQREMERREALCR 320
K +E++ + L + ++L+ E+ Q L + + L+ + + R+++ +EAL
Sbjct: 1246 KAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVS 1305
Query: 321 QLSESESSLEMDDERYFNEMSAQ 343
QLS + + E ++ +
Sbjct: 1306 QLSRGKQAFTQQIEELKRQLEEE 1328
Score = 48.9 bits (115), Expect = 1e-05
Identities = 66/294 (22%), Positives = 141/294 (47%), Gaps = 20/294 (6%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNT 115
LEE++ RL ++ ++E K + Q+ RDL +A++ +A A + +++
Sbjct: 1149 LEEISERL---EEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS 1205
Query: 116 ---LFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVN 172
L ++I LQ+ K+ L + E + ++L+ + + K LE+ + + E Q++
Sbjct: 1206 VAELGEQIDNLQRVKQKLEKE-KSEMKMEIDDLASNVETVSKAKGNLEK-MCRTLEDQLS 1263
Query: 173 KLMKKIKKLENDTISKQLTLEQ--LRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRI 230
+L K K+ E + LT ++ L+ E + L+ E+EALV++L + +
Sbjct: 1264 EL--KSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD-EKEALVSQLSRGKQAFTQQIEE 1320
Query: 231 LQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQY 290
L+ +L++ + A + ++ + S + +R E + K +L+ A + + ++AQ+
Sbjct: 1321 LKRQLEEEIKAKNA---LAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQW 1377
Query: 291 ---LEEERHMREENLR-LQRKLQREMERREALCRQLSESESSLEMDDERYFNEM 340
E + R E L ++KL + ++ E ++ +SLE +R NE+
Sbjct: 1378 RTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEV 1431
Score = 48.5 bits (114), Expect = 1e-05
Identities = 61/281 (21%), Positives = 116/281 (41%), Gaps = 23/281 (8%)
Query: 57 EELTNRLASLQQENKVLKIELETYKLKCKA-LQEENRDLRKASVTIQARAEQEEEFISN- 114
EE A LQ+ E+ ++ K + + +L +A + R + EE +
Sbjct: 1354 EEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAV 1413
Query: 115 -----TLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQ-- 167
+L K Q LQ E E L ++ E+ L +K AE +Q E+
Sbjct: 1414 NAKCASLEKTKQRLQNEVEDLMLDVERTNAACA-ALDKKQRNFDKILAEWKQKCEETHAE 1472
Query: 168 ----EFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDK 223
+ + L ++ K++N LE L+RE +L+ + E + KR+ +
Sbjct: 1473 LEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG-GKRIHE 1531
Query: 224 LE-AEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERL-------KKQ 275
LE +K++ QEK + + + + E + + +K+EV+R Q
Sbjct: 1532 LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1591
Query: 276 LRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERRE 316
L+ ++ E M L+ E R + +RL++K++ ++ E
Sbjct: 1592 LKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEME 1632
Score = 43.9 bits (102), Expect = 3e-04
Identities = 61/260 (23%), Positives = 112/260 (43%), Gaps = 35/260 (13%)
Query: 73 LKIELETYKLKCKALQEENRDLRKA-SVTIQARAEQEEEFISNTLFKKIQALQKEKETLA 131
LK +L + + LQ E +LR T ++R E+E + + +++Q L + +L
Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDAS--ERVQLLHTQNTSL- 1729
Query: 132 VNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLT 191
+N +K+ L + Q+Q E ++ Q +E + K + + + +Q T
Sbjct: 1730 INTKKK-------LETDISQMQGEMEDILQEARNAEE-KAKKAITDAAMMAEELKKEQDT 1781
Query: 192 LEQLRREKIDLENTL--------EQEQEAL------VNRLWKRMDKLEAEKRILQEKLDQ 237
L R K ++E T+ E EQ AL + +L R+ +LE E Q++ +
Sbjct: 1782 SAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAE 1841
Query: 238 PVSA-PPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERH 296
V R + E ++I L++ V++L+ ++++ + Q EE
Sbjct: 1842 AVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQ--------AEEAEE 1893
Query: 297 MREENLRLQRKLQREMERRE 316
NL RKLQ E+E E
Sbjct: 1894 QSNTNLAKFRKLQHELEEAE 1913
Score = 39.3 bits (90), Expect = 0.008
Identities = 56/288 (19%), Positives = 119/288 (41%), Gaps = 26/288 (9%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEE-----------NRDLRKASVTI-Q 102
++EEL +L + L L++ + C L+E+ R L KA+ + Q
Sbjct: 1317 QIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ 1376
Query: 103 ARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQH 162
R + E + I T + L++ K+ LA + EE + ++ K L+ K L+
Sbjct: 1377 WRTKYETDAIQRT-----EELEEAKKKLAQRLQAAEEHV-EAVNAKCASLEKTKQRLQNE 1430
Query: 163 LEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMD 222
+E + V + L+ + L + +++ + LE Q+ L +
Sbjct: 1431 VE-DLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKE-ARSLGTELF 1488
Query: 223 KLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQ 282
K+ K +E LDQ + +++ EI + +E+E++KKQ+ + +
Sbjct: 1489 KI---KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCE 1545
Query: 283 HSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLE 330
+ + H + LR+Q +L + + + R+++E + ++
Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELN---QVKSEVDRKIAEKDEEID 1590
Score = 38.1 bits (87), Expect = 0.018
Identities = 58/277 (20%), Positives = 118/277 (42%), Gaps = 32/277 (11%)
Query: 58 ELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLF 117
EL ++ +LQ+ + L+ E K++ L + KA ++ E+ +S
Sbjct: 1208 ELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKS 1267
Query: 118 KKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKK 177
K E+E++ L N+L+ + +LQ E E + L+ E+E V++L +
Sbjct: 1268 K----------------EEEQQRLINDLTAQRGRLQTESGEFSRQLD-EKEALVSQLSRG 1310
Query: 178 IKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQ 237
+ + LE+ + K L + L+ + + L ++ ++ + K LQ L +
Sbjct: 1311 KQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD-CDLLREQYEEEQESKAELQRALSK 1369
Query: 238 PVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEE-RH 296
+ R E D+ + E+E KK+L A +LQ +E+ + + +
Sbjct: 1370 ANTEVAQWR-TKYETDAIQR--------TEELEEAKKKL-AQRLQAAEEHVEAVNAKCAS 1419
Query: 297 MREENLRLQRK---LQREMERREALCRQLSESESSLE 330
+ + RLQ + L ++ER A C L + + + +
Sbjct: 1420 LEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456
Score = 30.8 bits (68), Expect = 2.8
Identities = 44/212 (20%), Positives = 94/212 (44%), Gaps = 26/212 (12%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLR---KASVTIQARAEQE--- 108
R++ L + SL K L+ ++ + + + + +E R+ K ++T A +E
Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777
Query: 109 EEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQE 168
E+ S L + + +++ + L + ++ E+ +++ +L+ ELE +E EQ+
Sbjct: 1778 EQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837
Query: 169 FQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAE- 227
+ +K ++K E K+LT + +E + RL +DKL+A+
Sbjct: 1838 RNA-EAVKGLRKHERRV--KELTYQ-------------TEEDRKNILRLQDLVDKLQAKV 1881
Query: 228 ---KRILQEKLDQPVSAPPSPRDISMEIDSPE 256
KR +E +Q + R + E++ E
Sbjct: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEEAE 1913
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 68.6 bits (166), Expect = 1e-11
Identities = 71/303 (23%), Positives = 137/303 (45%), Gaps = 38/303 (12%)
Query: 58 ELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLF 117
E +A++++E + +K EL + K K L+E+ L K +Q +
Sbjct: 850 ETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQ------------- 896
Query: 118 KKIQALQKEKETLAVNYEKEEEFLTN--ELSRKLMQLQHEKAELEQHLEQEQEFQVNKLM 175
+Q E E LA E+ ++ + +L K+ ++ E+AE E+ + E + KL
Sbjct: 897 -----VQAEAEGLADAEERCDQLIKTKIQLEAKIKEVT-ERAEDEEEINAELTAKKRKLE 950
Query: 176 KKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKL 235
+ +L+ D +LTL ++ +EK EN ++ E + L + + KL EK+ LQE
Sbjct: 951 DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG-LDETIAKLTKEKKALQEAH 1009
Query: 236 DQPVSAPPSPRD-----------ISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHS 284
Q + + D + ++D E + + L+ ++ER K++L L+ +
Sbjct: 1010 QQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE-GDLKLA 1068
Query: 285 EKMAQYLEEERHMREENLRLQR----KLQREMERREALCRQLSESESSLEMDDERYFNEM 340
++ +E E+ +E L+ + LQ ++E +AL QL + L+ E E+
Sbjct: 1069 QESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEI 1128
Query: 341 SAQ 343
A+
Sbjct: 1129 EAE 1131
Score = 61.2 bits (147), Expect = 2e-09
Identities = 75/338 (22%), Positives = 156/338 (46%), Gaps = 49/338 (14%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQE------E 109
+++L LA +++E + +++ + L E L K +Q +Q E
Sbjct: 960 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE 1019
Query: 110 EFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSR--------------KLMQLQHE 155
E NTL K L+++ + L + E+E++ L +L R +M +++E
Sbjct: 1020 EDKVNTLTKAKIKLEQQVDDLEGSLEQEKK-LRMDLERAKRKLEGDLKLAQESIMDIENE 1078
Query: 156 KAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVN 215
K +L++ L+++ EF+++ L KI+ + I Q +++L+ +LE +E E+ +
Sbjct: 1079 KQQLDEKLKKK-EFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAK 1137
Query: 216 RLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQ 275
+R D L E + E+L++ A + +++ + ++ MR E L+ +
Sbjct: 1138 AEKQRSD-LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR----DLEEATLQHE 1192
Query: 276 LRAAQL--QHSEKMAQYLEEERHMREENLRLQR-KLQREME----------------RRE 316
AA L +H++ +A+ E+ +++ +L++ K + +ME E
Sbjct: 1193 ATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLE 1252
Query: 317 ALCRQLSESESSL---EMDDERYFNEMSAQGLRPRTVS 351
+CR L + S L E + +R N+++AQ R +T S
Sbjct: 1253 KMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTES 1290
Score = 60.8 bits (146), Expect = 3e-09
Identities = 73/323 (22%), Positives = 136/323 (42%), Gaps = 60/323 (18%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKC----KALQEENRDLRKASVTIQARAEQEEE 110
+LE+ + L ++ K L+++LE K K K QE D+ + + +++E
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091
Query: 111 FISNT-------------LFKKIQALQKEKETLAVNYEKEE------EFLTNELSRKLMQ 151
ISN L KKI+ LQ E L E E E ++LSR+L +
Sbjct: 1092 EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1151
Query: 152 LQHE--------KAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLE 203
+ A++E + ++E EFQ K + LE T+ + T LR++ D
Sbjct: 1152 ISERLEEAGGATSAQIEMNKKREAEFQ-----KMRRDLEEATLQHEATAATLRKKHADSV 1206
Query: 204 NTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIR 263
L ++ ++ L + KLE EK ++ MEID + + +
Sbjct: 1207 AELGEQ----IDNLQRVKQKLEKEKS-----------------EMKMEIDDLASNVETVS 1245
Query: 264 FLKNEVERLKKQL--RAAQLQHSEKMAQYLEEERHMREENLRLQR-KLQREMERREALCR 320
K +E++ + L + ++L+ E+ Q L + + L+ + + R+++ +EAL
Sbjct: 1246 KAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVS 1305
Query: 321 QLSESESSLEMDDERYFNEMSAQ 343
QLS + + E ++ +
Sbjct: 1306 QLSRGKQAFTQQIEELKRQLEEE 1328
Score = 48.9 bits (115), Expect = 1e-05
Identities = 66/294 (22%), Positives = 141/294 (47%), Gaps = 20/294 (6%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNT 115
LEE++ RL ++ ++E K + Q+ RDL +A++ +A A + +++
Sbjct: 1149 LEEISERL---EEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS 1205
Query: 116 ---LFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVN 172
L ++I LQ+ K+ L + E + ++L+ + + K LE+ + + E Q++
Sbjct: 1206 VAELGEQIDNLQRVKQKLEKE-KSEMKMEIDDLASNVETVSKAKGNLEK-MCRTLEDQLS 1263
Query: 173 KLMKKIKKLENDTISKQLTLEQ--LRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRI 230
+L K K+ E + LT ++ L+ E + L+ E+EALV++L + +
Sbjct: 1264 EL--KSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD-EKEALVSQLSRGKQAFTQQIEE 1320
Query: 231 LQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQY 290
L+ +L++ + A + ++ + S + +R E + K +L+ A + + ++AQ+
Sbjct: 1321 LKRQLEEEIKAKNA---LAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQW 1377
Query: 291 ---LEEERHMREENLR-LQRKLQREMERREALCRQLSESESSLEMDDERYFNEM 340
E + R E L ++KL + ++ E ++ +SLE +R NE+
Sbjct: 1378 RTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEV 1431
Score = 48.5 bits (114), Expect = 1e-05
Identities = 61/281 (21%), Positives = 116/281 (41%), Gaps = 23/281 (8%)
Query: 57 EELTNRLASLQQENKVLKIELETYKLKCKA-LQEENRDLRKASVTIQARAEQEEEFISN- 114
EE A LQ+ E+ ++ K + + +L +A + R + EE +
Sbjct: 1354 EEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAV 1413
Query: 115 -----TLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQ-- 167
+L K Q LQ E E L ++ E+ L +K AE +Q E+
Sbjct: 1414 NAKCASLEKTKQRLQNEVEDLMLDVERTNAACA-ALDKKQRNFDKILAEWKQKCEETHAE 1472
Query: 168 ----EFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDK 223
+ + L ++ K++N LE L+RE +L+ + E + KR+ +
Sbjct: 1473 LEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG-GKRIHE 1531
Query: 224 LE-AEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERL-------KKQ 275
LE +K++ QEK + + + + E + + +K+EV+R Q
Sbjct: 1532 LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1591
Query: 276 LRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERRE 316
L+ ++ E M L+ E R + +RL++K++ ++ E
Sbjct: 1592 LKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEME 1632
Score = 43.9 bits (102), Expect = 3e-04
Identities = 61/260 (23%), Positives = 112/260 (43%), Gaps = 35/260 (13%)
Query: 73 LKIELETYKLKCKALQEENRDLRKA-SVTIQARAEQEEEFISNTLFKKIQALQKEKETLA 131
LK +L + + LQ E +LR T ++R E+E + + +++Q L + +L
Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDAS--ERVQLLHTQNTSL- 1729
Query: 132 VNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLT 191
+N +K+ L + Q+Q E ++ Q +E + K + + + +Q T
Sbjct: 1730 INTKKK-------LETDISQMQGEMEDILQEARNAEE-KAKKAITDAAMMAEELKKEQDT 1781
Query: 192 LEQLRREKIDLENTL--------EQEQEAL------VNRLWKRMDKLEAEKRILQEKLDQ 237
L R K ++E T+ E EQ AL + +L R+ +LE E Q++ +
Sbjct: 1782 SAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAE 1841
Query: 238 PVSA-PPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERH 296
V R + E ++I L++ V++L+ ++++ + Q EE
Sbjct: 1842 AVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQ--------AEEAEE 1893
Query: 297 MREENLRLQRKLQREMERRE 316
NL RKLQ E+E E
Sbjct: 1894 QSNTNLAKFRKLQHELEEAE 1913
Score = 39.3 bits (90), Expect = 0.008
Identities = 56/288 (19%), Positives = 119/288 (41%), Gaps = 26/288 (9%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEE-----------NRDLRKASVTI-Q 102
++EEL +L + L L++ + C L+E+ R L KA+ + Q
Sbjct: 1317 QIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ 1376
Query: 103 ARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQH 162
R + E + I T + L++ K+ LA + EE + ++ K L+ K L+
Sbjct: 1377 WRTKYETDAIQRT-----EELEEAKKKLAQRLQAAEEHV-EAVNAKCASLEKTKQRLQNE 1430
Query: 163 LEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMD 222
+E + V + L+ + L + +++ + LE Q+ L +
Sbjct: 1431 VE-DLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKE-ARSLGTELF 1488
Query: 223 KLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQ 282
K+ K +E LDQ + +++ EI + +E+E++KKQ+ + +
Sbjct: 1489 KI---KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCE 1545
Query: 283 HSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLE 330
+ + H + LR+Q +L + + + R+++E + ++
Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELN---QVKSEVDRKIAEKDEEID 1590
Score = 38.1 bits (87), Expect = 0.018
Identities = 58/277 (20%), Positives = 118/277 (42%), Gaps = 32/277 (11%)
Query: 58 ELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLF 117
EL ++ +LQ+ + L+ E K++ L + KA ++ E+ +S
Sbjct: 1208 ELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKS 1267
Query: 118 KKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKK 177
K E+E++ L N+L+ + +LQ E E + L+ E+E V++L +
Sbjct: 1268 K----------------EEEQQRLINDLTAQRGRLQTESGEFSRQLD-EKEALVSQLSRG 1310
Query: 178 IKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQ 237
+ + LE+ + K L + L+ + + L ++ ++ + K LQ L +
Sbjct: 1311 KQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD-CDLLREQYEEEQESKAELQRALSK 1369
Query: 238 PVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEE-RH 296
+ R E D+ + E+E KK+L A +LQ +E+ + + +
Sbjct: 1370 ANTEVAQWR-TKYETDAIQR--------TEELEEAKKKL-AQRLQAAEEHVEAVNAKCAS 1419
Query: 297 MREENLRLQRK---LQREMERREALCRQLSESESSLE 330
+ + RLQ + L ++ER A C L + + + +
Sbjct: 1420 LEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456
Score = 30.8 bits (68), Expect = 2.8
Identities = 44/212 (20%), Positives = 94/212 (44%), Gaps = 26/212 (12%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLR---KASVTIQARAEQE--- 108
R++ L + SL K L+ ++ + + + + +E R+ K ++T A +E
Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777
Query: 109 EEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQE 168
E+ S L + + +++ + L + ++ E+ +++ +L+ ELE +E EQ+
Sbjct: 1778 EQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837
Query: 169 FQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAE- 227
+ +K ++K E K+LT + +E + RL +DKL+A+
Sbjct: 1838 RNA-EAVKGLRKHERRV--KELTYQ-------------TEEDRKNILRLQDLVDKLQAKV 1881
Query: 228 ---KRILQEKLDQPVSAPPSPRDISMEIDSPE 256
KR +E +Q + R + E++ E
Sbjct: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEEAE 1913
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 68.2 bits (165), Expect = 2e-11
Identities = 81/353 (22%), Positives = 167/353 (47%), Gaps = 44/353 (12%)
Query: 13 AGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELTNRLASLQQENKV 72
AG + S ++TSGG G + + S + +L + SL+Q+ K
Sbjct: 42 AGAKTKKKKTDSSPETTTSGGCHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQ 101
Query: 73 LKIELET--------YKLKCKALQE------ENRDLRKASVTIQARA---EQEEEFISNT 115
++ +LE +K + + L+ E DL+ + A E+E + ++
Sbjct: 102 VEHQLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGR 161
Query: 116 LFKKIQALQK-EKETLAVNYEKEEEFLTNE-----LSRKLMQLQHEKAELEQHLEQEQEF 169
L +Q +Q+ E+ AV+ +++EE ++ L R L Q E+A L H+ Q
Sbjct: 162 LQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIKERALLNAHVTQ---- 217
Query: 170 QVNKLMKKIKKLENDTISKQLTLEQLRRE----KIDLE-NTLEQEQEALVNRLWKRMDKL 224
V + +K+++ LE D +K + E+ R + K+ +E TL++E++ ++R+ +L
Sbjct: 218 -VTESLKQVQ-LERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRI----QEL 271
Query: 225 EAEKRILQEKLDQPVS-APPSPRDISMEI-DSPENMMRHIRFLKNEVERLKKQLRAAQLQ 282
E L+ ++ +P S APP+ + ++ D +++ + + L+ +++ + +A L
Sbjct: 272 ERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLL 331
Query: 283 HSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDER 335
E+ + E+E +RE+ + R+ +R E+ E +L E + +L+ ER
Sbjct: 332 SKEQKQRLQEQEEMLREQEAQRVREQERLCEQNE----RLREQQKTLQEQGER 380
Score = 51.2 bits (121), Expect = 2e-06
Identities = 63/271 (23%), Positives = 116/271 (42%), Gaps = 45/271 (16%)
Query: 59 LTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFK 118
+T+ + LQ E K L+ E+E + K ++ E N+ L S + R +++EE + +
Sbjct: 293 VTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQ 352
Query: 119 KIQALQKEKETLAVNYEK--EEEFLTNELSRKLMQLQHEKAELEQHLEQEQEF------- 169
++ +E+E L E+ E++ E +L + + + E+ L +E+E
Sbjct: 353 RV----REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKR 408
Query: 170 ---QVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEA 226
Q +L KK ++L+ ++L L Q K+D + Q +N K +LE
Sbjct: 409 LWDQEERLWKKEERLQKQ--EERLALSQ--NHKLDKQLAEPQCSFEDLNNEKKSALQLEQ 464
Query: 227 EKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEK 286
+ + LQEKLD+ H+ ++ ++L+ QL L
Sbjct: 465 QVKELQEKLDE----------------------EHLEAASHQNQQLETQLSLVALPGEGD 502
Query: 287 MAQYLEEERHMREENLRLQRKLQREMERREA 317
Q+L+ E EE R + ++E REA
Sbjct: 503 GGQHLDSE---EEEAPRPTPNIPEDLESREA 530
Score = 50.4 bits (119), Expect = 3e-06
Identities = 63/274 (22%), Positives = 120/274 (43%), Gaps = 36/274 (13%)
Query: 59 LTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFK 118
L + + + K +++E + Y K + ++ R ++++AR +EE+
Sbjct: 211 LNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWKMSVEARTLKEEK---KRDIH 266
Query: 119 KIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKI 178
+IQ L++ L + ++ + QLQ E +HL QE E KL ++
Sbjct: 267 RIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEA----KHLRQEVEGLEGKLQSQV 322
Query: 179 KKLENDTISKQLTLEQLRREKIDLENTLEQEQEAL--VNRLWKRMDKLEAEKRILQEKLD 236
EN+ L+ EQ +R + E EQE + + RL ++ ++L +++ LQE+
Sbjct: 323 ---ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQ-- 377
Query: 237 QPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERH 296
E + + + L+ + ERL+K+ +LQ EK EE
Sbjct: 378 ------------------GERLRKQEQRLRKQEERLRKE--EERLQKQEKRLWDQEERLW 417
Query: 297 MREENLRLQRKLQREMERREALCRQLSESESSLE 330
+EE L+ Q + + + + L +QL+E + S E
Sbjct: 418 KKEERLQKQEE-RLALSQNHKLDKQLAEPQCSFE 450
>gi|187761324 shootin1 isoform a [Homo sapiens]
Length = 631
Score = 67.4 bits (163), Expect = 3e-11
Identities = 95/444 (21%), Positives = 183/444 (41%), Gaps = 58/444 (13%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
+++EL +++ S+Q+E K+L IELE K K + EE +++ + + ++ + +
Sbjct: 143 QIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQRKVLEK 202
Query: 115 TLFKKIQALQKEKETLAVNYEKEEEFL-------------TNELSR-------------K 148
+ A++ E E + VN E E++ N+L R +
Sbjct: 203 CNRVSMLAVE-EYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIPDQQ 261
Query: 149 LMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQL-----TLEQLRREKIDLE 203
L++ E A+L Q LE+E+ K+ + ++LEN+T+ K++ LE L +K +LE
Sbjct: 262 LLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELE 321
Query: 204 NTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIR 263
+ +E N L +D+L +KR+ Q + P PP P + ++M IR
Sbjct: 322 LKYQNSEEKARN-LKHSVDEL--QKRVNQSENSVPPPPPPPPPLPPPPPNPIRSLMSMIR 378
Query: 264 FLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENL-RLQRKLQREMERREALCRQL 322
+ K+ +A Q + +E++ + +R EE + R+++ + + A +
Sbjct: 379 KRSHPSGSGAKKEKATQPETTEEVT---DLKRQAVEEMMDRIKKGVHLRPVNQTARPKTK 435
Query: 323 SESESSLE--MDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFT 380
ES E +D+ + + R++ S P R + A +
Sbjct: 436 PESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENSETELERILRRRKVTAE--ADSS 493
Query: 381 PPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQP 440
PT + S + +G+ +T+ + + +F P+PP P
Sbjct: 494 SPTGILA------TSESKSMPVLGSVSSVTKTALNKKTLEAEFNSPSPP---------TP 538
Query: 441 PPPPPPPPMQPTVPSAATSQPTPS 464
P P ++ S T QP S
Sbjct: 539 EPGEGPRKLEGCTSSKVTFQPPSS 562
Score = 47.4 bits (111), Expect = 3e-05
Identities = 84/432 (19%), Positives = 167/432 (38%), Gaps = 71/432 (16%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAE---QEEEF 111
+L+ +T+ E + L+ E + K KC +++E + K Q + +E F
Sbjct: 9 QLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAVKKLEEFQKISHMVIEEVNF 68
Query: 112 ISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQV 171
+ N L + + ++ E LA KE + L + +L + E +++ E
Sbjct: 69 MQNHLEIE-KTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINIDDEDSTTD 127
Query: 172 N----------KLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRM 221
+ K+IK+L + +S Q E+ + I+LEN + E + + +
Sbjct: 128 TDGAAETCVSVQCQKQIKELRDQIVSVQ---EEKKILAIELENLKSKLVEVI-----EEV 179
Query: 222 DKLEAEKRILQ-EKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQ 280
+K++ EK +L E L+Q R + ++ E M ++ L+K LR
Sbjct: 180 NKVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLE--------LEKDLRKKA 231
Query: 281 LQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESES-SLEMDDERYFNE 339
+++M ++E+ + R+ +L LQ + + L + L E+ + ++++ER ++
Sbjct: 232 ESFAQEM--FIEQNKLKRQSHLLLQSSIPDQQ-----LLKALDENAKLTQQLEEERIQHQ 284
Query: 340 MSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLH 399
+ L + + + + L + Y NS
Sbjct: 285 QKVKELEEQLENETLH-----KEIHNLKQQLELLEE--------DKKELELKYQNS---E 328
Query: 400 VQHMGTSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATS 459
+ H + R + S + PPPPPPPPP+ P P+ S
Sbjct: 329 EKARNLKHSVDELQKRVNQSENSV----------------PPPPPPPPPLPPPPPNPIRS 372
Query: 460 QPTPSQHSAHPS 471
+ + +HPS
Sbjct: 373 LMSMIRKRSHPS 384
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 67.0 bits (162), Expect = 4e-11
Identities = 82/332 (24%), Positives = 147/332 (44%), Gaps = 58/332 (17%)
Query: 45 KSGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLK----CKALQEENRDL------ 94
K G++ +LE+ T+ L ++ K L+ +LE K K K QE DL
Sbjct: 1020 KVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQ 1079
Query: 95 ------RKASVTIQARAEQEEEFISNTLFKK--------IQALQKEKE---TLAVNYEKE 137
+K Q +A+ ++E + + F+K I+ L++E E TL EK+
Sbjct: 1080 IEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQ 1139
Query: 138 EEFLTNELSRKLMQLQH----EKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLE 193
L EL +L+ A++E + ++E EFQ K + LE T+ + T
Sbjct: 1140 RSDLARELEEISERLEEASGATSAQIEMNKKREAEFQ-----KMRRDLEEATLQHEATAA 1194
Query: 194 QLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEID 253
LR+++ D L ++ ++ L + KLE EK L+ ++D S +I
Sbjct: 1195 TLRKKQADSVAELGEQ----IDNLQRVKQKLEKEKSELKMEIDDMAS------NIEALSK 1244
Query: 254 SPENMMRHIRFLKNEVERLK-KQLRAAQLQHSEKMAQYLEEERHMREENLRLQR-KLQRE 311
S N+ R R ++++ +K K + QL H + +M++ L+ Q +L
Sbjct: 1245 SKSNIERTCRTVEDQFSEIKAKDEQQTQLIH----------DLNMQKARLQTQNGELSHR 1294
Query: 312 MERREALCRQLSESESSLEMDDERYFNEMSAQ 343
+E +E+L QL++S+ +L E +M +
Sbjct: 1295 VEEKESLISQLTKSKQALTQQLEELKRQMEEE 1326
Score = 63.5 bits (153), Expect = 4e-10
Identities = 58/272 (21%), Positives = 124/272 (45%), Gaps = 28/272 (10%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
+++ELT RL ++ N L + + KC +L+ + DL ++ E + N
Sbjct: 922 KVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKN 981
Query: 115 ------TLFKKIQALQKEKETLAVNYEKE------EEFLTNELSRKLMQLQHEKAELEQH 162
L + I L KEK++L +++ EE N L + +L+ + +LE
Sbjct: 982 LSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGS 1041
Query: 163 LEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMD 222
LEQE++ + + L + +KLE D Q ++ L +K +E L++++ L ++L ++D
Sbjct: 1042 LEQEKKLRAD-LERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFEL-SQLQAKID 1099
Query: 223 KLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQ 282
+ Q+K+ +++ I+ E + L+ ++E+ + L +
Sbjct: 1100 DEQVHSLQFQKKI----------KELQARIEELEEEIEAEHTLRAKIEKQRSDL----AR 1145
Query: 283 HSEKMAQYLEEERHMREENLRLQRKLQREMER 314
E++++ LEE + + +K + E ++
Sbjct: 1146 ELEEISERLEEASGATSAQIEMNKKREAEFQK 1177
Score = 60.1 bits (144), Expect = 4e-09
Identities = 64/256 (25%), Positives = 111/256 (43%), Gaps = 30/256 (11%)
Query: 104 RAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHL 163
R E EE+ +S K LQ + ET N EE + K++ L+ + EL + L
Sbjct: 874 RKELEEKMVSLLQEKNDLQLQVQSET--ENLMDAEERCEGLIKSKIL-LEAKVKELTERL 930
Query: 164 EQEQEFQVNKLMKK------IKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRL 217
E+E+E + KK L+ D +LTL ++ +EK EN ++ E + L
Sbjct: 931 EEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEM-TAL 989
Query: 218 WKRMDKLEAEKRILQEKLDQPVSAPPSPRD-----------ISMEIDSPENMMRHIRFLK 266
+ + KL EK+ LQE Q + D + + D E + + L+
Sbjct: 990 EENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLR 1049
Query: 267 NEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLR--------LQRKLQREMERREAL 318
++ER K++L L+ S++ LE ++ EE L+ LQ K+ E
Sbjct: 1050 ADLERAKRKLE-GDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQF 1108
Query: 319 CRQLSESESSLEMDDE 334
+++ E ++ +E +E
Sbjct: 1109 QKKIKELQARIEELEE 1124
Score = 58.9 bits (141), Expect = 1e-08
Identities = 71/306 (23%), Positives = 138/306 (45%), Gaps = 33/306 (10%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNT 115
+ +L + A LQ +N L +E + L + + L + ++ + E+E + N
Sbjct: 1274 IHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETK-AKNA 1332
Query: 116 LFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLE-------QEQE 168
+ +Q+ + + + L YE+E+E EL R L + E A+ E +E E
Sbjct: 1333 MAHALQSSRHDCDLLREQYEEEQE-AKAELQRALSKANSEVAQWRTKYETDAIQRTEELE 1391
Query: 169 FQVNKLMKKIKKLENDT-------ISKQLTLEQLRREKIDLENTLEQEQE--ALVNRLWK 219
KL +++++ E +T S + T ++L+ E DL LE+ A +++ +
Sbjct: 1392 EAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQR 1451
Query: 220 RMDKLEAE-KRILQEKLDQPVSAPPSPRDISME-----------IDSPENMMRHIRFLKN 267
DK+ AE K+ L E + +A R +S E +D E + R + L+
Sbjct: 1452 NFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQE 1511
Query: 268 EVERLKKQL--RAAQLQHSEKMAQYLEEERHMREENL-RLQRKLQREMERREALCRQLSE 324
E+ L +Q+ LQ +EK + +E+E+ + L ++ L+ E + + +LS+
Sbjct: 1512 EISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQ 1571
Query: 325 SESSLE 330
+S L+
Sbjct: 1572 VKSELD 1577
Score = 50.4 bits (119), Expect = 3e-06
Identities = 64/297 (21%), Positives = 120/297 (40%), Gaps = 25/297 (8%)
Query: 57 EELTNRLASLQQENKVLKIELETYKLKCKA-LQEENRDLRKASVTIQARAEQEEEFISN- 114
EE A LQ+ E+ ++ K + + +L +A + R ++ EE
Sbjct: 1352 EEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETA 1411
Query: 115 -----TLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQ-- 167
+L K Q LQ E E L + E+ L +K AE +Q L++ Q
Sbjct: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACAT-LDKKQRNFDKVLAEWKQKLDESQAE 1470
Query: 168 ----EFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDK 223
+ + L ++ K+ N LE LRRE +L+ + E + +
Sbjct: 1471 LEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEA 1530
Query: 224 LEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLK-------KQL 276
+ +K + QEK D V+ + E + + +K+E++R +QL
Sbjct: 1531 EKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQL 1590
Query: 277 RAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALC----RQLSESESSL 329
+ + +E + L+ E R + LRL++K++ ++ E RQ++E++ L
Sbjct: 1591 KRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHL 1647
Score = 45.4 bits (106), Expect = 1e-04
Identities = 56/256 (21%), Positives = 109/256 (42%), Gaps = 28/256 (10%)
Query: 56 LEELTNRLASLQQENKVLKI---ELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFI 112
LEEL +L+Q + ++ EL + + L +N L ++A Q + +
Sbjct: 1686 LEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEV 1745
Query: 113 SNTLFKKIQALQKEKETL------AVNYEKEE------EFLTNELSRKLMQLQHEKAELE 160
N++ + A +K K+ + A +KE+ E + L + + LQH E E
Sbjct: 1746 ENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE 1805
Query: 161 QHLEQEQEFQVNKLMKKIKKLEND-TISKQLTLEQLR-----REKIDLENTLEQEQEALV 214
Q + + Q+ KL ++++LEN+ + ++ E L+ K+ +E +
Sbjct: 1806 QLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNI 1865
Query: 215 NRLWKRMDKLEAE----KRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVE 270
RL +DKL+A+ KR +E +Q + R + E+ E +++V
Sbjct: 1866 LRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHEL---EEAAERADIAESQVN 1922
Query: 271 RLKKQLRAAQLQHSEK 286
+L+ + R Q E+
Sbjct: 1923 KLRAKSRDVGSQKMEE 1938
Score = 44.7 bits (104), Expect = 2e-04
Identities = 57/273 (20%), Positives = 119/273 (43%), Gaps = 40/273 (14%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
+L+E L + Q+E++ L EL + + + ++ LR+ + +Q E I+
Sbjct: 1463 KLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAE 1522
Query: 115 TLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKL 174
T K +Q +K K+ + E+E+ L L L+HE++++ +V
Sbjct: 1523 T-GKNLQEAEKTKKLV----EQEKSDLQVALEEVEGSLEHEESKI---------LRVQLE 1568
Query: 175 MKKIK-KLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQE 233
+ ++K +L+ I K +EQL+R + E Q L + R D L +K++ +
Sbjct: 1569 LSQVKSELDRKVIEKDEEIEQLKRNS---QRAAEALQSVLDAEIRSRNDALRLKKKMEGD 1625
Query: 234 KLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEV--------------ERLKKQLRAA 279
+ + S R ++ +H+R ++ ++ E LK+QL
Sbjct: 1626 LNEMEIQLGHSNRQMA-------ETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIV 1678
Query: 280 QLQHSEKMAQYLEEERHMREENLRLQRKLQREM 312
+ + + + + LEE + E+ R +R ++E+
Sbjct: 1679 E-RRNGLLLEELEEMKVALEQTERTRRLSEQEL 1710
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 66.6 bits (161), Expect = 5e-11
Identities = 70/299 (23%), Positives = 136/299 (45%), Gaps = 41/299 (13%)
Query: 58 ELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLF 117
E +A++++E + K EL + K K L+E+ L K +Q +
Sbjct: 847 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQ------------- 893
Query: 118 KKIQALQKEKETLAVNYEKEEEFLTN--ELSRKLMQLQHEKAELEQHLEQEQEFQVNKLM 175
+Q E ++LA E+ E+ + N +L K+ ++ E+AE E+ + E + KL
Sbjct: 894 -----VQSEADSLADAEERCEQLIKNKIQLEAKIKEVT-ERAEEEEEINAELTAKKRKLE 947
Query: 176 KKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKL 235
+ +L+ D +LTL ++ +EK EN ++ E + L + + KL EK+ LQE
Sbjct: 948 DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG-LDETIAKLSKEKKALQETH 1006
Query: 236 DQPVSAPPSPRD-----------ISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHS 284
Q + + D + ++D E + + L+ ++ER K+ +L+
Sbjct: 1007 QQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKR-----KLEGD 1061
Query: 285 EKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQ 343
K+AQ E M + +L KL+++ L ++ E E ++E+ ++ E+ A+
Sbjct: 1062 LKLAQ--ESTMDMENDKQQLDEKLEKKEFEISNLISKI-EDEQAVEIQLQKKIKELQAR 1117
Score = 48.9 bits (115), Expect = 1e-05
Identities = 69/296 (23%), Positives = 140/296 (47%), Gaps = 24/296 (8%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNT 115
LEE++ RL ++ ++E K + Q+ RDL +A++ +A + +++
Sbjct: 1146 LEEISERL---EEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADS 1202
Query: 116 ---LFKKIQALQKEKETLAVNYEKEEEFL---TNELSRKLMQLQHEKAELEQHLEQEQEF 169
L ++I LQ+ K+ L EKE+ L T++LS + K LE+ + + E
Sbjct: 1203 MAELGEQIDNLQRVKQKL----EKEKSELKMETDDLSSNAEAISKAKGNLEK-MCRSLED 1257
Query: 170 QVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLE-QEQEALVNRLWKRMDKLEAEK 228
QV++L K K+ E + LT ++ R + E + + E++ALV++L + +
Sbjct: 1258 QVSEL--KTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQI 1315
Query: 229 RILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMA 288
L+ +L++ A + ++ + S + +R E + K +L+ A + + ++A
Sbjct: 1316 EELKHQLEEETKAKNA---LAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVA 1372
Query: 289 QY---LEEERHMREENLR-LQRKLQREMERREALCRQLSESESSLEMDDERYFNEM 340
Q+ E + R E L ++KL + ++ E ++ +SLE +R NE+
Sbjct: 1373 QWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEV 1428
Score = 44.3 bits (103), Expect = 2e-04
Identities = 70/305 (22%), Positives = 127/305 (41%), Gaps = 37/305 (12%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDL-RKASVTIQARAEQEEEFISN 114
L+E L + + LK +L + + LQ E +L T ++R E+E +
Sbjct: 1653 LKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDA 1712
Query: 115 TLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKL 174
+ +++Q L + +L +N +K+ L N++S QLQ E E+ Q +E + K
Sbjct: 1713 S--ERVQLLHTQNTSL-INTKKK---LENDVS----QLQSEVEEVIQESRNAEE-KAKKA 1761
Query: 175 MKKIKKLENDTISKQLTLEQLRREKIDLENTL--------EQEQEALVNRLWKRMDKLEA 226
+ + + +Q T L R K +LE T+ E EQ AL K++ KLEA
Sbjct: 1762 ITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK-KQIQKLEA 1820
Query: 227 EKRILQEKLDQPVSAPPS--------PRDISMEIDSPENMMRHIRFLKNEVERLKKQLRA 278
R L+ +++ R + E +++ L++ V++L+ ++++
Sbjct: 1821 RVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKS 1880
Query: 279 AQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFN 338
+ Q EE NL RKLQ E+E E + L +
Sbjct: 1881 YKRQ--------AEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHT 1932
Query: 339 EMSAQ 343
++SA+
Sbjct: 1933 KISAE 1937
Score = 43.9 bits (102), Expect = 3e-04
Identities = 62/296 (20%), Positives = 124/296 (41%), Gaps = 66/296 (22%)
Query: 56 LEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNT 115
+ EL ++ +LQ+ + L+ E K++ L + KA ++ E+ +S
Sbjct: 1203 MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSEL 1262
Query: 116 LFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLM 175
K E+E++ L N+L+ + +LQ E E + L+ E++ V++L
Sbjct: 1263 KTK----------------EEEQQRLINDLTAQRARLQTEAGEYSRQLD-EKDALVSQLS 1305
Query: 176 KKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKL 235
+ SKQ + +Q+ +L++ LE+E +A N L + + +L+E+
Sbjct: 1306 R----------SKQASTQQIE----ELKHQLEEETKA-KNALAHALQSSRHDCDLLREQY 1350
Query: 236 DQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSE-------KMA 288
++ E + + R + +EV + + + +Q +E K+A
Sbjct: 1351 EE-------------EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1397
Query: 289 QYLEE-ERHMREENL----------RLQRK---LQREMERREALCRQLSESESSLE 330
Q L+E E H+ N RLQ + L ++ER A C L + + + +
Sbjct: 1398 QRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFD 1453
Score = 43.9 bits (102), Expect = 3e-04
Identities = 59/303 (19%), Positives = 123/303 (40%), Gaps = 29/303 (9%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEE-----------NRDLRKASVTI-Q 102
++EEL ++L + L L++ + C L+E+ R L KA+ + Q
Sbjct: 1314 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ 1373
Query: 103 ARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQH 162
R + E + I T + L++ K+ LA ++ EE + ++ K L+ K L+
Sbjct: 1374 WRTKYETDAIQRT-----EELEEAKKKLAQRLQEAEEHV-EAVNAKCASLEKTKQRLQNE 1427
Query: 163 LEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLE---QEQEALVNRLWK 219
+E + V + L+ + L + +++ + + LE +E +L L+K
Sbjct: 1428 VE-DLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFK 1486
Query: 220 RMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAA 279
K + +E LDQ + +++ EI + +E+E++KKQ+
Sbjct: 1487 -------VKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQE 1539
Query: 280 QLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNE 339
+ + + + H + LR+Q +L + + + E L+ + R
Sbjct: 1540 KCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVET 1599
Query: 340 MSA 342
M +
Sbjct: 1600 MQS 1602
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 66.2 bits (160), Expect = 6e-11
Identities = 78/344 (22%), Positives = 157/344 (45%), Gaps = 29/344 (8%)
Query: 12 GAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELTNRLASLQQENK 71
G GG S G GGGG GGGG G G V P ++E+T + LQ N
Sbjct: 108 GFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLN- 166
Query: 72 VLKIELETYKLKCKALQE-ENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETL 130
++I+ E K+K + ++ ++ + + AS + R +++ + T ++ +Q Q + T
Sbjct: 167 -VEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQ--QVDTSTR 223
Query: 131 AVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQ---EFQVNKLMKKIKK---LEND 184
N E E N L R++ QL+ +++ L+ L+ Q E NK +I K EN+
Sbjct: 224 THNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENE 283
Query: 185 TISKQLTLEQLRREKIDLENTLEQEQEAL--VNRLWKRMDKLEAEKRILQEKLDQPVSAP 242
++ + ++ K+DL+ L+ Q+ + + L+ +AE +Q ++ +
Sbjct: 284 FVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALY------QAELSQMQTQISETNVIL 337
Query: 243 PSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSE------KMAQYLEEERH 296
+ S+++DS ++ ++ ++ + K + A L S+ ++ + R+
Sbjct: 338 SMDNNRSLDLDS---IIAEVKAQYEDIAQ-KSKAEAESLYQSKYEELQITAGRHGDSVRN 393
Query: 297 MREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEM 340
+ E L R +QR + + +Q+S + S+ ++R N +
Sbjct: 394 SKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENAL 437
Score = 38.9 bits (89), Expect = 0.010
Identities = 19/45 (42%), Positives = 20/45 (44%)
Query: 4 SASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGG 48
S S G GG S SS GG GGGGGG GG+ G
Sbjct: 561 SGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSG 605
Score = 37.7 bits (86), Expect = 0.023
Identities = 20/44 (45%), Positives = 22/44 (50%), Gaps = 5/44 (11%)
Query: 12 GAGGNSSSSAAMQSSCSSTSGGGGGGGG-----GGGGGKSGGIV 50
G GG S + SS G GGGGGG G GGG SGG +
Sbjct: 570 GGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSI 613
Score = 36.2 bits (82), Expect = 0.067
Identities = 17/37 (45%), Positives = 19/37 (51%)
Query: 12 GAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGG 48
G GG S + S + G GGGGGGG G SGG
Sbjct: 520 GGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGG 556
Score = 35.0 bits (79), Expect = 0.15
Identities = 24/56 (42%), Positives = 27/56 (48%), Gaps = 12/56 (21%)
Query: 5 ASESDTDGAGGNSSSSAAM-------QSSCSSTSGGGGG-----GGGGGGGGKSGG 48
+S S GG SS SA + SS + SGGGGG GGGGG G GG
Sbjct: 6 SSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGG 61
Score = 34.7 bits (78), Expect = 0.19
Identities = 18/44 (40%), Positives = 20/44 (45%)
Query: 4 SASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSG 47
S S G GG S ++ S S GGGGGGG G G G
Sbjct: 513 SGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGG 556
Score = 33.9 bits (76), Expect = 0.33
Identities = 17/45 (37%), Positives = 18/45 (40%)
Query: 4 SASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGG 48
S S + G G S SS GGG G GGGGG G
Sbjct: 506 STSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRG 550
Score = 33.9 bits (76), Expect = 0.33
Identities = 17/36 (47%), Positives = 18/36 (50%)
Query: 12 GAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSG 47
G GG S + SS S G G GGGGGG G G
Sbjct: 544 GGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYG 579
Score = 33.5 bits (75), Expect = 0.43
Identities = 18/45 (40%), Positives = 20/45 (44%)
Query: 4 SASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGG 48
S S S T +GG S +S G GGG G GGG GG
Sbjct: 504 SVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGG 548
Score = 33.5 bits (75), Expect = 0.43
Identities = 20/54 (37%), Positives = 22/54 (40%), Gaps = 17/54 (31%)
Query: 12 GAGGNSSSSAAMQSSCSSTSGGGGGGG-----------------GGGGGGKSGG 48
G G S ++ S S GGGGGG GGGGGG SGG
Sbjct: 548 GRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGG 601
Score = 33.1 bits (74), Expect = 0.56
Identities = 14/28 (50%), Positives = 19/28 (67%)
Query: 20 SAAMQSSCSSTSGGGGGGGGGGGGGKSG 47
S ++ +S ++ SGGG GGGGGG G G
Sbjct: 502 SVSVSTSHTTISGGGSRGGGGGGYGSGG 529
Score = 33.1 bits (74), Expect = 0.56
Identities = 17/41 (41%), Positives = 18/41 (43%)
Query: 4 SASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGG 44
S S G GG + S SGGG G GGGGGG
Sbjct: 534 SGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGG 574
Score = 32.7 bits (73), Expect = 0.74
Identities = 15/42 (35%), Positives = 21/42 (50%)
Query: 7 ESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGG 48
E + G + + ++ S S T+ GGG GGGGGG G
Sbjct: 487 EGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSG 528
Score = 32.7 bits (73), Expect = 0.74
Identities = 18/37 (48%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 12 GAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGG 48
G+GG+S S S S GGGGG G G GG S G
Sbjct: 526 GSGGSSYGSGG--GSYGSGGGGGGGRGSYGSGGSSYG 560
Score = 32.7 bits (73), Expect = 0.74
Identities = 15/37 (40%), Positives = 17/37 (45%)
Query: 12 GAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGG 48
G+GG S S+ G GGG G GGGG G
Sbjct: 540 GSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHG 576
Score = 32.7 bits (73), Expect = 0.74
Identities = 18/44 (40%), Positives = 19/44 (43%), Gaps = 7/44 (15%)
Query: 12 GAGGNSSSSAAMQSSCSSTSGGGGGG-------GGGGGGGKSGG 48
G G S S + SGGGGGG GGG GG GG
Sbjct: 572 GGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGG 615
Score = 32.3 bits (72), Expect = 0.96
Identities = 16/37 (43%), Positives = 17/37 (45%)
Query: 12 GAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGG 48
G GG S S + GG G GGGGGG S G
Sbjct: 543 GGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYG 579
Score = 32.0 bits (71), Expect = 1.3
Identities = 15/37 (40%), Positives = 15/37 (40%)
Query: 12 GAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGG 48
G GG S S G GGGGGGG G G
Sbjct: 519 GGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSG 555
Score = 32.0 bits (71), Expect = 1.3
Identities = 16/44 (36%), Positives = 19/44 (43%)
Query: 6 SESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGI 49
S S + G G S S + GG GG GG G SGG+
Sbjct: 580 SGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGV 623
Score = 31.6 bits (70), Expect = 1.6
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 4 SASESDTDGAGGNSSSSAAMQSSCSSTSGGG-GGGGGGGGGGKSGG 48
S+S G+GG S+ + S +SGG GG G GG KS G
Sbjct: 582 SSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSG 627
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 66.2 bits (160), Expect = 6e-11
Identities = 71/307 (23%), Positives = 145/307 (47%), Gaps = 32/307 (10%)
Query: 54 FRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFIS 113
F+++ L + A ++E +K E E K + + + ++L + VT+ QE+
Sbjct: 838 FKIKPLL-KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLM----QEK---- 888
Query: 114 NTLFKKIQALQKEKETLAVNYEKEEEFLTN--ELSRKLMQLQHEKAELEQHLEQEQEFQV 171
N L ++QA E ++LA E+ ++ + +L K+ ++ E+AE E+ + E +
Sbjct: 889 NDLQLQVQA---EADSLADAEERCDQLIKTKIQLEAKIKEVT-ERAEDEEEINAELTAKK 944
Query: 172 NKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRIL 231
KL + +L+ D +LTL ++ +EK EN ++ E + L + + KL EK+ L
Sbjct: 945 RKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG-LDETIAKLTKEKKAL 1003
Query: 232 QEKLDQPVSAPPSPRD-----------ISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQ 280
QE Q + + D + ++D E + + ++ ++ER K++L
Sbjct: 1004 QEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLE-GD 1062
Query: 281 LQHSEKMAQYLEEERHMREENLRLQR----KLQREMERREALCRQLSESESSLEMDDERY 336
L+ +++ +E ++ +E L+ + LQ ++E +AL QL + L+ E
Sbjct: 1063 LKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEEL 1122
Query: 337 FNEMSAQ 343
E+ A+
Sbjct: 1123 EEEIEAE 1129
Score = 53.9 bits (128), Expect = 3e-07
Identities = 74/353 (20%), Positives = 152/353 (43%), Gaps = 72/353 (20%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
+LE+ + L ++ K ++++LE K K L+ + + +++++ I+ +Q +E +
Sbjct: 1030 KLEQQVDDLEGSLEQEKKIRMDLERAKRK---LEGDLKLAQESTMDIENDKQQLDEKLKK 1086
Query: 115 TLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQ------- 167
F+ + LQ + E +E+ L +L +K+ +LQ ELE+ +E E+
Sbjct: 1087 KEFE-MSGLQSKIE--------DEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAE 1137
Query: 168 --------------------------EFQVNK-----LMKKIKKLENDTISKQLTLEQLR 196
+ ++NK K + LE T+ + T LR
Sbjct: 1138 KQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLR 1197
Query: 197 REKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVS----APPSPRDISMEI 252
++ D L ++ ++ L + KLE EK ++ ++D S + ++
Sbjct: 1198 KKHADSVAELGEQ----IDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMC 1253
Query: 253 DSPENMMRHIRFLKNEVERLKKQLRA--AQLQ-HSEKMAQYLEEERHMREENLR------ 303
+ E+ + I+ + E +RL L A A+LQ S + ++ L+E+ + + R
Sbjct: 1254 RALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFT 1313
Query: 304 -----LQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVS 351
L+R+L+ E++ + AL L S ++ E+Y E A+ R +S
Sbjct: 1314 QQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMS 1366
Score = 49.3 bits (116), Expect = 8e-06
Identities = 61/285 (21%), Positives = 121/285 (42%), Gaps = 31/285 (10%)
Query: 57 EELTNRLASLQQENKVLKIELETYKLKCKA-LQEENRDLRKASVTIQARAEQEEEFISN- 114
EE A LQ+ E+ ++ K + + +L +A + R + EE +
Sbjct: 1352 EEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAV 1411
Query: 115 -----TLFKKIQALQKEKETLAVNYE----------KEEEFLTNELSRKLMQLQHEKAEL 159
+L K Q LQ E E L ++ E K++ L+ + + AEL
Sbjct: 1412 NAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAEL 1471
Query: 160 EQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWK 219
E Q++ ++ + KIK +++ + LE L+RE +L+ + E + K
Sbjct: 1472 EA--SQKESRSLSTELFKIKNAYEESLDQ---LETLKRENKNLQQEISDLTEQIAEG-GK 1525
Query: 220 RMDKLE-AEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERL------ 272
R+ +LE +K++ QEK + + + + E + + +K+EV+R
Sbjct: 1526 RIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1585
Query: 273 -KKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERRE 316
Q++ ++ E M L+ E R + +RL++K++ ++ E
Sbjct: 1586 EIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEME 1630
Score = 48.5 bits (114), Expect = 1e-05
Identities = 66/337 (19%), Positives = 140/337 (41%), Gaps = 60/337 (17%)
Query: 63 LASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQA 122
L S ++ + L ++L+ + +A EE + +A +A+AE++ +S L + +
Sbjct: 1094 LQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER 1153
Query: 123 LQKE----KETLAVNYEKEEEFLTNELSRKLMQLQHEKAEL---EQHLEQEQEF--QVNK 173
L++ + +N ++E EF + LQHE ++H + E Q++
Sbjct: 1154 LEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDN 1213
Query: 174 LMKKIKKLENDTISKQLTLEQLRREKIDL---ENTLEQEQEALVNRLWKRMDKLEAEKRI 230
L + +KLE + ++ ++ L + + LE+ AL ++L + K E ++R+
Sbjct: 1214 LQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRL 1273
Query: 231 LQEKLDQPVSAPPSPRDISMEIDSPENMMRHI----RFLKNEVERLKKQLRAAQLQHSEK 286
+ + Q + S ++D + ++ + + ++E LK+QL +++
Sbjct: 1274 INDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEE-EIKAKSA 1332
Query: 287 MAQYLEEERH-------MREENLRLQRKLQREM--------------------------E 313
+A L+ RH EE + +LQR M E
Sbjct: 1333 LAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEE 1392
Query: 314 RREALCRQLSESE----------SSLEMDDERYFNEM 340
++ L ++L ++E +SLE +R NE+
Sbjct: 1393 AKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEV 1429
Score = 43.1 bits (100), Expect = 5e-04
Identities = 52/253 (20%), Positives = 123/253 (48%), Gaps = 21/253 (8%)
Query: 73 LKIELETYKLKCKALQEENRDLRKA-SVTIQARAEQEEEFISNTLFKKIQALQKEKETLA 131
LK +L + + LQ E +LR T ++R E+E + + +++Q L + +L
Sbjct: 1671 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDAS--ERVQLLHTQNTSL- 1727
Query: 132 VNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLT 191
+N +K+ E +++ ++ + E E+ ++ + +++KK ++ + +
Sbjct: 1728 INTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAIT-DAAMMAEELKKEQDTSAHLERM 1786
Query: 192 LEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLD----QPVSAPPSPRD 247
+ L + DL++ L++ ++ + K++ KLEA R L+ +++ + V A R
Sbjct: 1787 KKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRK 1846
Query: 248 ISMEID----SPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLR 303
++ E ++I L++ V++L+ A+++ ++ A+ EE+ ++ NL
Sbjct: 1847 HERKVKELTYQTEEDRKNILRLQDLVDKLQ-----AKVKSYKRQAEEAEEQSNV---NLS 1898
Query: 304 LQRKLQREMERRE 316
R++Q E+E E
Sbjct: 1899 KFRRIQHELEEAE 1911
Score = 41.2 bits (95), Expect = 0.002
Identities = 55/287 (19%), Positives = 122/287 (42%), Gaps = 24/287 (8%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
++EEL +L + L L++ + C L+E+ + ++A +Q + ++
Sbjct: 1315 QIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQ 1374
Query: 115 TLFK-------KIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQ 167
K + + L++ K+ LA + EE + ++ K L+ K L+ +E +
Sbjct: 1375 WRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV-EAVNAKCASLEKTKQRLQNEVE-DL 1432
Query: 168 EFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLE---QEQEALVNRLWKRMDKL 224
V + L+ + L + +++ + LE +E +L L+K
Sbjct: 1433 MIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKI---- 1488
Query: 225 EAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHS 284
K +E LDQ + +++ EI + +E+E++KKQ+ + + S
Sbjct: 1489 ---KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQV---EQEKS 1542
Query: 285 EKMAQYLEEERHMREENLRLQRKLQREMER-REALCRQLSESESSLE 330
E A E E + E ++ R +Q E+ + + + R+++E + ++
Sbjct: 1543 ELQAALEEAEASLEHEEGKILR-IQLELNQVKSEVDRKIAEKDEEID 1588
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 65.9 bits (159), Expect = 8e-11
Identities = 75/326 (23%), Positives = 155/326 (47%), Gaps = 41/326 (12%)
Query: 62 RLASLQQENKVLKIELETYKLKCKALQEENRDLRK-ASVTIQARAEQEEEFISNTLFKKI 120
++ L++ NK L +ELE K K L + N LR+ S+ A A++E + + L ++
Sbjct: 1099 KIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNL--QV 1156
Query: 121 QALQKEKE-----------TLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEF 169
QA+ + KE L + EKE+E N L ++ + E +H F
Sbjct: 1157 QAVLQRKEEEDRQMKHLVQALQASLEKEKE-KVNSLKEQVAAAKVEAGHNRRH------F 1209
Query: 170 QVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKR 229
+ L ++ +++ + +K+ +++L+ E DL+ E + + + + + A+ +
Sbjct: 1210 KAASL--ELSEVKKELQAKEHLVQKLQAEADDLQ-IREGKHSQEIAQFQAELAEARAQLQ 1266
Query: 230 ILQEKLDQPVSAPP----SPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSE 285
+LQ++LD+ +S P ++ E+D E R I+ LK +++ ++Q R +L+ +
Sbjct: 1267 LLQKQLDEQLSKQPVGNQEMENLKWEVDQKE---REIQSLKQQLDLTEQQGR-KELEGLQ 1322
Query: 286 KMAQYLEEERHMREENLRLQRK----LQREMERREALCRQLSESESSLEMDDERYFNEMS 341
++ Q ++ E M +E+L + +K LQ ++ + + L + L++D R +
Sbjct: 1323 QLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKTR 1382
Query: 342 AQGLRPRTVSSP-----IPYTPSPSS 362
+ + S+P IP P P+S
Sbjct: 1383 KEPKGEASSSNPATPIKIPDCPVPAS 1408
Score = 58.2 bits (139), Expect = 2e-08
Identities = 71/293 (24%), Positives = 130/293 (44%), Gaps = 42/293 (14%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFIS- 113
RL+ + + ASL+Q+ + +K+ L + +ALQ+E+ DL K Q + E+ +
Sbjct: 683 RLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDA 742
Query: 114 -NTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVN 172
T + ++QA E + A + E + LQ+EK LE L+ + +
Sbjct: 743 LQTHYDELQARLGELQGEAASRED-----------TICLLQNEKIILEAALQAAKSGK-E 790
Query: 173 KLMKKIKKLENDTISKQLTLEQLRRE---KIDLENTLEQEQEALVNRLWKRMDKLEAEKR 229
+L + ++LE T TLE+LR E K L+QE AL ++ ++
Sbjct: 791 ELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQM----------QK 840
Query: 230 ILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQ-HSEK-- 286
I ++ L Q V RD + S + ++ ++ + ++ K+LR +Q H EK
Sbjct: 841 IKEQFLQQKVMVEAYRRDAT----SKDQLISELKATRKRLDSELKELRQELMQVHGEKRT 896
Query: 287 ----MAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDER 335
+++ E +R+ L+ LQ + R+ + L SL+ D E+
Sbjct: 897 AEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHL----QSLQFDKEQ 945
Score = 52.4 bits (124), Expect = 9e-07
Identities = 63/295 (21%), Positives = 131/295 (44%), Gaps = 25/295 (8%)
Query: 58 ELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLF 117
E + + +E L+ +LE L+ +E +L+ + + + + E S++
Sbjct: 402 ETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVE-CSHSSQ 460
Query: 118 KKIQALQKEKETLAVN---YEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKL 174
++ +L E +TL + E+ L N L K L +L+ EQ Q +L
Sbjct: 461 QRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQ-----RL 515
Query: 175 MKKIKKLENDTISKQLTLEQLRREKIDLENTLEQ---EQEALVNRLWKRMDKLEAEKRIL 231
M K++ ++ +SK T+ LR++ L++ L+Q E+ L ++L ++ + + +
Sbjct: 516 MAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVR 575
Query: 232 QEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYL 291
Q Q A + + E M HI+ + L + L+ + S+++ +
Sbjct: 576 QWYQQQLALAQEARVRLQGE-------MAHIQVGQMTQAGLLEHLKLENVSLSQQLTE-- 626
Query: 292 EEERHMREENLRLQRKLQ---REMERREALCRQLSESESSLEMDDERYFNEMSAQ 343
+ R M+E+ R+ +LQ +M +EA Q+ E+++ +E D +R E +
Sbjct: 627 TQHRSMKEKG-RIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGE 680
Score = 51.2 bits (121), Expect = 2e-06
Identities = 57/260 (21%), Positives = 117/260 (45%), Gaps = 18/260 (6%)
Query: 66 LQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQK 125
LQ E +++ T + L+ EN L + Q R+ +E+ I+ L + I+A
Sbjct: 592 LQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQLTETQHRSMKEKGRIAAQL-QGIEADML 650
Query: 126 EKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDT 185
++E + ++ + + +L R+L + + E+ L++ + + K+ L+ D
Sbjct: 651 DQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQ 710
Query: 186 ISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSP 245
LE L++E +DL L QEAL +R + +D L+ LQ +L + S
Sbjct: 711 -----QLEALQQEHLDLMKQLTLTQEALQSR-EQSLDALQTHYDELQARLGELQGEAASR 764
Query: 246 RDISMEIDSP----ENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEE-------E 294
D + + E ++ + K E++R ++L + SE + + EE
Sbjct: 765 EDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQV 824
Query: 295 RHMREENLRLQRKLQREMER 314
H+++E L++++Q+ E+
Sbjct: 825 EHLQQETAALKKQMQKIKEQ 844
Score = 45.8 bits (107), Expect = 8e-05
Identities = 63/288 (21%), Positives = 125/288 (43%), Gaps = 23/288 (7%)
Query: 56 LEELTNRLASLQQENKVLKIELETY---KLKCKALQEENRDLRKASVTIQARAEQ---EE 109
+ +L L S Q+E ++ L++ K + A+ E N L+K +Q A + E+
Sbjct: 915 MADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQ 974
Query: 110 EFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEF 169
+ L + + QKE +T YE L+ L L + AEL Q Q
Sbjct: 975 KQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSS 1034
Query: 170 QVN-KLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEK 228
+ L ++I+ LE + + + L +E ++ QE E ++ + D+L+ E
Sbjct: 1035 DSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQ-ES 1093
Query: 229 RILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMA 288
R ++K+ + S + +++E++ + + + Q AA +H+ +
Sbjct: 1094 RGFRKKIKR---LEESNKKLALELEHEKGKLTGLG-----------QSNAALREHNSILE 1139
Query: 289 QYL-EEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDER 335
L + E + + NL++Q LQR+ E + + ++SLE + E+
Sbjct: 1140 TALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEK 1187
>gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 2 [Homo sapiens]
Length = 595
Score = 65.5 bits (158), Expect = 1e-10
Identities = 75/302 (24%), Positives = 150/302 (49%), Gaps = 44/302 (14%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
++ L N + SL+Q+ K ++ +LE K KA E + R+ V IQ Q+EE ++
Sbjct: 84 KISRLKNTIKSLKQQKKQVEHQLEEEK---KANNERQKAERELEVQIQTLIIQKEELNTD 140
Query: 115 T--LFKKIQALQKEKETLAVNYEKEEEF---LTNELS-------RKLMQLQ-----HEKA 157
+ + ++ ++E + LAV + + L + LS +K QL H +
Sbjct: 141 LYHMERSLRYFEEESKDLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEW 200
Query: 158 ELEQHLEQEQ--EFQVNKLMKKIKKL--ENDTISKQLTLEQLR----REKIDLEN-TLEQ 208
ELEQ L+ + + Q+ +L + ++L E D ++ + E+ R K+ E TL++
Sbjct: 201 ELEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKK 260
Query: 209 EQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNE 268
E++ + +R+++LE L+ ++ +P+ PP P + E++ ++ L+ E
Sbjct: 261 EKQQDM----RRVEELERSLSKLKNQMAEPL--PPEPPAVPSEVE--------LQHLRKE 306
Query: 269 VERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESS 328
+ER+ +L++ + +E +RE+ RL+++ +R E+ E L RQL++ +S
Sbjct: 307 LERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKL-RQLAKPQSV 365
Query: 329 LE 330
E
Sbjct: 366 FE 367
>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 65.5 bits (158), Expect = 1e-10
Identities = 75/302 (24%), Positives = 150/302 (49%), Gaps = 44/302 (14%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
++ L N + SL+Q+ K ++ +LE K KA E + R+ V IQ Q+EE ++
Sbjct: 92 KISRLKNTIKSLKQQKKQVEHQLEEEK---KANNERQKAERELEVQIQTLIIQKEELNTD 148
Query: 115 T--LFKKIQALQKEKETLAVNYEKEEEF---LTNELS-------RKLMQLQ-----HEKA 157
+ + ++ ++E + LAV + + L + LS +K QL H +
Sbjct: 149 LYHMERSLRYFEEESKDLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEW 208
Query: 158 ELEQHLEQEQ--EFQVNKLMKKIKKL--ENDTISKQLTLEQLR----REKIDLEN-TLEQ 208
ELEQ L+ + + Q+ +L + ++L E D ++ + E+ R K+ E TL++
Sbjct: 209 ELEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKK 268
Query: 209 EQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNE 268
E++ + +R+++LE L+ ++ +P+ PP P + E++ ++ L+ E
Sbjct: 269 EKQQDM----RRVEELERSLSKLKNQMAEPL--PPEPPAVPSEVE--------LQHLRKE 314
Query: 269 VERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESS 328
+ER+ +L++ + +E +RE+ RL+++ +R E+ E L RQL++ +S
Sbjct: 315 LERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKL-RQLAKPQSV 373
Query: 329 LE 330
E
Sbjct: 374 FE 375
Score = 34.7 bits (78), Expect = 0.19
Identities = 53/255 (20%), Positives = 108/255 (42%), Gaps = 28/255 (10%)
Query: 62 RLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQ 121
R++ + QE LK E + + ++E R L K + E + + + ++Q
Sbjct: 255 RMSKMSQEICTLKKEKQQ---DMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEV--ELQ 309
Query: 122 ALQKEKETLAVNYEKEEE-----FLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMK 176
L+KE E +A + + + L N + ++ Q E+ ++ QEQ ++ +L K
Sbjct: 310 HLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAK 369
Query: 177 KIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQ---- 232
E + TL QL ++ +L+ L +E + ++ +L A+ ++
Sbjct: 370 PQSVFEELNNENKSTL-QLEQQVKELQEKLGEEH---LEAASQQNQQLTAQLSLMALPGE 425
Query: 233 ----EKLDQPVSAPPSPR-DISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKM 287
E LD P P + +++S E M + LK + + L + ++ +L +
Sbjct: 426 GHGGEHLDSEGEEAPQPMPSVPEDLESREAMSSFMDHLKEKAD-LSELVKKQEL----RF 480
Query: 288 AQYLEEERHMREENL 302
QY +E H + +L
Sbjct: 481 IQYWQERCHQKIHHL 495
>gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 2 [Homo sapiens]
Length = 595
Score = 65.5 bits (158), Expect = 1e-10
Identities = 75/302 (24%), Positives = 150/302 (49%), Gaps = 44/302 (14%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
++ L N + SL+Q+ K ++ +LE K KA E + R+ V IQ Q+EE ++
Sbjct: 84 KISRLKNTIKSLKQQKKQVEHQLEEEK---KANNERQKAERELEVQIQTLIIQKEELNTD 140
Query: 115 T--LFKKIQALQKEKETLAVNYEKEEEF---LTNELS-------RKLMQLQ-----HEKA 157
+ + ++ ++E + LAV + + L + LS +K QL H +
Sbjct: 141 LYHMERSLRYFEEESKDLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEW 200
Query: 158 ELEQHLEQEQ--EFQVNKLMKKIKKL--ENDTISKQLTLEQLR----REKIDLEN-TLEQ 208
ELEQ L+ + + Q+ +L + ++L E D ++ + E+ R K+ E TL++
Sbjct: 201 ELEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKK 260
Query: 209 EQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNE 268
E++ + +R+++LE L+ ++ +P+ PP P + E++ ++ L+ E
Sbjct: 261 EKQQDM----RRVEELERSLSKLKNQMAEPL--PPEPPAVPSEVE--------LQHLRKE 306
Query: 269 VERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESS 328
+ER+ +L++ + +E +RE+ RL+++ +R E+ E L RQL++ +S
Sbjct: 307 LERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKL-RQLAKPQSV 365
Query: 329 LE 330
E
Sbjct: 366 FE 367
>gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 65.5 bits (158), Expect = 1e-10
Identities = 75/302 (24%), Positives = 150/302 (49%), Gaps = 44/302 (14%)
Query: 55 RLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISN 114
++ L N + SL+Q+ K ++ +LE K KA E + R+ V IQ Q+EE ++
Sbjct: 92 KISRLKNTIKSLKQQKKQVEHQLEEEK---KANNERQKAERELEVQIQTLIIQKEELNTD 148
Query: 115 T--LFKKIQALQKEKETLAVNYEKEEEF---LTNELS-------RKLMQLQ-----HEKA 157
+ + ++ ++E + LAV + + L + LS +K QL H +
Sbjct: 149 LYHMERSLRYFEEESKDLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEW 208
Query: 158 ELEQHLEQEQ--EFQVNKLMKKIKKL--ENDTISKQLTLEQLR----REKIDLEN-TLEQ 208
ELEQ L+ + + Q+ +L + ++L E D ++ + E+ R K+ E TL++
Sbjct: 209 ELEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKK 268
Query: 209 EQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNE 268
E++ + +R+++LE L+ ++ +P+ PP P + E++ ++ L+ E
Sbjct: 269 EKQQDM----RRVEELERSLSKLKNQMAEPL--PPEPPAVPSEVE--------LQHLRKE 314
Query: 269 VERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESS 328
+ER+ +L++ + +E +RE+ RL+++ +R E+ E L RQL++ +S
Sbjct: 315 LERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKL-RQLAKPQSV 373
Query: 329 LE 330
E
Sbjct: 374 FE 375
Score = 32.3 bits (72), Expect = 0.96
Identities = 53/255 (20%), Positives = 107/255 (41%), Gaps = 28/255 (10%)
Query: 62 RLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQ 121
R++ + QE LK E + + ++E R L K + E + + + ++Q
Sbjct: 255 RMSKMSQEICTLKKEKQQ---DMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEV--ELQ 309
Query: 122 ALQKEKETLAVNYEKEEE-----FLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMK 176
L+KE E +A + + + L N + ++ Q E+ ++ QEQ ++ +L K
Sbjct: 310 HLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAK 369
Query: 177 KIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQ---- 232
E + TL QL ++ +L+ L +E + ++ +L A+ ++
Sbjct: 370 PQSVFEELNNENKSTL-QLEQQVKELQEKLGEEH---LEAASQQNQQLTAQLSLMALPGE 425
Query: 233 ----EKLDQPVSAPPSPR-DISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKM 287
E LD P P + + +S E M + LK + + L + ++ +L +
Sbjct: 426 GHGGEHLDSEGEEAPRPMPSVPEDPESREAMSSFMDHLKEKAD-LSELVKKQEL----RF 480
Query: 288 AQYLEEERHMREENL 302
QY +E H + +L
Sbjct: 481 IQYWQERCHQKIHHL 495
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,526,476
Number of Sequences: 37866
Number of extensions: 1520105
Number of successful extensions: 68527
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1538
Number of HSP's successfully gapped in prelim test: 1968
Number of HSP's that attempted gapping in prelim test: 21670
Number of HSP's gapped (non-prelim): 24108
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.