BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|46592978 ATP-binding cassette sub-family G member 1 isoform 7 [Homo sapiens] (663 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|46592978 ATP-binding cassette sub-family G member 1 isoform 7... 1325 0.0 gi|46592956 ATP-binding cassette sub-family G member 1 isoform 3... 1303 0.0 gi|46592964 ATP-binding cassette sub-family G member 1 isoform 5... 1302 0.0 gi|46592898 ATP-binding cassette sub-family G member 1 isoform 2... 1301 0.0 gi|46592915 ATP-binding cassette sub-family G member 1 isoform 4... 1292 0.0 gi|46592971 ATP-binding cassette sub-family G member 1 isoform 6... 1286 0.0 gi|215820660 ATP-binding cassette, subfamily G, member 4 [Homo s... 922 0.0 gi|20143975 ATP-binding cassette, subfamily G, member 4 [Homo sa... 922 0.0 gi|62526033 ATP-binding cassette, sub-family G, member 2 [Homo s... 261 1e-69 gi|11967971 ATP-binding cassette sub-family G member 8 [Homo sap... 226 5e-59 gi|11967969 ATP-binding cassette sub-family G member 5 [Homo sap... 209 5e-54 gi|27881501 ATP-binding cassette, sub-family A, member 12 isofor... 91 3e-18 gi|30795238 ATP-binding cassette, sub-family A, member 12 isofor... 91 3e-18 gi|105990541 ATP-binding cassette, sub-family A member 4 [Homo s... 90 6e-18 gi|153792144 ATP-binding cassette, sub-family A, member 10 [Homo... 89 1e-17 gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13... 87 6e-17 gi|21536376 ATP-binding cassette, sub-family A member 1 [Homo sa... 86 1e-16 gi|116734710 ATP-binding cassette, sub-family A member 3 [Homo s... 82 1e-15 gi|27436953 ATP-binding cassette, sub-family A, member 6 [Homo s... 82 2e-15 gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo ... 82 2e-15 gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo ... 82 2e-15 gi|9961250 ATP-binding cassette, subfamily B, member 4 isoform B... 81 4e-15 gi|9961252 ATP-binding cassette, subfamily B, member 4 isoform C... 81 4e-15 gi|4505771 ATP-binding cassette, subfamily B, member 4 isoform A... 81 4e-15 gi|45446740 ATP-binding cassette, sub-family A, member 2 isoform... 81 4e-15 gi|47078218 ATP-binding cassette, sub-family A, member 2 isoform... 81 4e-15 gi|150417984 ATP-binding cassette, sub-family A, member 7 [Homo ... 81 4e-15 gi|9955968 ATP-binding cassette, sub-family B (MDR/TAP), member ... 80 6e-15 gi|9955966 ATP-binding cassette, sub-family B (MDR/TAP), member ... 80 6e-15 gi|45243524 ATP-binding cassette, sub-family B (MDR/TAP), member... 80 6e-15 >gi|46592978 ATP-binding cassette sub-family G member 1 isoform 7 [Homo sapiens] Length = 663 Score = 1325 bits (3428), Expect = 0.0 Identities = 663/663 (100%), Positives = 663/663 (100%) Query: 1 MIMRLPQPHGTNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEA 60 MIMRLPQPHGTNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEA Sbjct: 1 MIMRLPQPHGTNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEA 60 Query: 61 QRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAG 120 QRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAG Sbjct: 61 QRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAG 120 Query: 121 KSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAH 180 KSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAH Sbjct: 121 KSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAH 180 Query: 181 LKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEP 240 LKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEP Sbjct: 181 LKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEP 240 Query: 241 TSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCN 300 TSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCN Sbjct: 241 TSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCN 300 Query: 301 LVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEV 360 LVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEV Sbjct: 301 LVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEV 360 Query: 361 NPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGL 420 NPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGL Sbjct: 361 NPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGL 420 Query: 421 LIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSL 480 LIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSL Sbjct: 421 LIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSL 480 Query: 481 KAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLI 540 KAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLI Sbjct: 481 KAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLI 540 Query: 541 GAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYG 600 GAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYG Sbjct: 541 GAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYG 600 Query: 601 LDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIR 660 LDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIR Sbjct: 601 LDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIR 660 Query: 661 AER 663 AER Sbjct: 661 AER 663 >gi|46592956 ATP-binding cassette sub-family G member 1 isoform 3 [Homo sapiens] Length = 677 Score = 1303 bits (3372), Expect = 0.0 Identities = 653/653 (100%), Positives = 653/653 (100%) Query: 11 TNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRA 70 TNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRA Sbjct: 25 TNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRA 84 Query: 71 AVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAG 130 AVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAG Sbjct: 85 AVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAG 144 Query: 131 YRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGR 190 YRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGR Sbjct: 145 YRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGR 204 Query: 191 REMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 250 REMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF Sbjct: 205 REMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 264 Query: 251 QVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGL 310 QVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGL Sbjct: 265 QVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGL 324 Query: 311 NCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSE 370 NCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSE Sbjct: 325 NCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSE 384 Query: 371 EDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIG 430 EDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIG Sbjct: 385 EDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIG 444 Query: 431 NEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMA 490 NEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMA Sbjct: 445 NEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMA 504 Query: 491 DVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVA 550 DVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVA Sbjct: 505 DVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVA 564 Query: 551 TFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDI 610 TFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDI Sbjct: 565 TFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDI 624 Query: 611 DETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 663 DETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER Sbjct: 625 DETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 677 >gi|46592964 ATP-binding cassette sub-family G member 1 isoform 5 [Homo sapiens] Length = 668 Score = 1302 bits (3369), Expect = 0.0 Identities = 653/657 (99%), Positives = 654/657 (99%) Query: 7 QPHGTNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSL 66 +P NASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSL Sbjct: 12 KPCPQNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSL 71 Query: 67 PRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMN 126 PRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMN Sbjct: 72 PRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMN 131 Query: 127 ILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEK 186 ILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEK Sbjct: 132 ILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEK 191 Query: 187 DEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 246 DEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS Sbjct: 192 DEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 251 Query: 247 ASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLR 306 ASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLR Sbjct: 252 ASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLR 311 Query: 307 DLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWH 366 DLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWH Sbjct: 312 DLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWH 371 Query: 367 RPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLY 426 RPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLY Sbjct: 372 RPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLY 431 Query: 427 LGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLA 486 LGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLA Sbjct: 432 LGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLA 491 Query: 487 KTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTS 546 KTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTS Sbjct: 492 KTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTS 551 Query: 547 LQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDL 606 LQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDL Sbjct: 552 LQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDL 611 Query: 607 HCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 663 HCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER Sbjct: 612 HCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 668 >gi|46592898 ATP-binding cassette sub-family G member 1 isoform 2 [Homo sapiens] Length = 666 Score = 1301 bits (3367), Expect = 0.0 Identities = 652/652 (100%), Positives = 652/652 (100%) Query: 12 NASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAA 71 NASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAA Sbjct: 15 NASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAA 74 Query: 72 VNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGY 131 VNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGY Sbjct: 75 VNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGY 134 Query: 132 RETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRR 191 RETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRR Sbjct: 135 RETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRR 194 Query: 192 EMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ 251 EMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ Sbjct: 195 EMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ 254 Query: 252 VVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLN 311 VVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLN Sbjct: 255 VVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLN 314 Query: 312 CPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEE 371 CPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEE Sbjct: 315 CPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEE 374 Query: 372 DSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGN 431 DSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGN Sbjct: 375 DSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGN 434 Query: 432 EAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMAD 491 EAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMAD Sbjct: 435 EAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMAD 494 Query: 492 VPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVAT 551 VPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVAT Sbjct: 495 VPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVAT 554 Query: 552 FVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDID 611 FVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDID Sbjct: 555 FVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDID 614 Query: 612 ETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 663 ETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER Sbjct: 615 ETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 666 >gi|46592915 ATP-binding cassette sub-family G member 1 isoform 4 [Homo sapiens] Length = 678 Score = 1292 bits (3344), Expect = 0.0 Identities = 652/664 (98%), Positives = 652/664 (98%), Gaps = 12/664 (1%) Query: 12 NASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAA 71 NASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAA Sbjct: 15 NASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAA 74 Query: 72 VNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGY 131 VNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGY Sbjct: 75 VNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGY 134 Query: 132 RETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRR 191 RETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRR Sbjct: 135 RETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRR 194 Query: 192 EMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ 251 EMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ Sbjct: 195 EMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ 254 Query: 252 VVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLN 311 VVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLN Sbjct: 255 VVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLN 314 Query: 312 CPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEE 371 CPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEE Sbjct: 315 CPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEE 374 Query: 372 ------------DSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIG 419 DSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIG Sbjct: 375 VKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIG 434 Query: 420 LLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYS 479 LLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYS Sbjct: 435 LLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYS 494 Query: 480 LKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLL 539 LKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLL Sbjct: 495 LKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLL 554 Query: 540 IGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIY 599 IGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIY Sbjct: 555 IGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIY 614 Query: 600 GLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKI 659 GLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKI Sbjct: 615 GLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKI 674 Query: 660 RAER 663 RAER Sbjct: 675 RAER 678 >gi|46592971 ATP-binding cassette sub-family G member 1 isoform 6 [Homo sapiens] Length = 644 Score = 1286 bits (3329), Expect = 0.0 Identities = 644/644 (100%), Positives = 644/644 (100%) Query: 20 MTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDL 79 MTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDL Sbjct: 1 MTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDL 60 Query: 80 SYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGA 139 SYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGA Sbjct: 61 SYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGA 120 Query: 140 VLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILT 199 VLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILT Sbjct: 121 VLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILT 180 Query: 200 ALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGL 259 ALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGL Sbjct: 181 ALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGL 240 Query: 260 AQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPA 319 AQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPA Sbjct: 241 AQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPA 300 Query: 320 DFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEDSSSMEGC 379 DFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEDSSSMEGC Sbjct: 301 DFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEDSSSMEGC 360 Query: 380 HSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSN 439 HSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSN Sbjct: 361 HSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSN 420 Query: 440 SGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFP 499 SGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFP Sbjct: 421 SGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFP 480 Query: 500 VAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAI 559 VAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAI Sbjct: 481 VAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAI 540 Query: 560 PVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQKS 619 PVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQKS Sbjct: 541 PVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQKS 600 Query: 620 EAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 663 EAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER Sbjct: 601 EAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 644 >gi|215820660 ATP-binding cassette, subfamily G, member 4 [Homo sapiens] Length = 646 Score = 922 bits (2383), Expect = 0.0 Identities = 459/625 (73%), Positives = 536/625 (85%), Gaps = 4/625 (0%) Query: 39 EATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLL 98 + E +L HLKKV+N++TEAQRFS LP+R+AV+IEF +LSYSV EGP WRK+GYKTLL Sbjct: 26 DGAEPPVLTTHLKKVENHITEAQRFSHLPKRSAVDIEFVELSYSVREGPCWRKRGYKTLL 85 Query: 99 KGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCY 158 K +SGKF EL+ IMGPSGAGKST MNILAGYRE+GMKG +L+NG PR+LR FRK+SCY Sbjct: 86 KCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCY 145 Query: 159 IMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQ 218 IMQDDMLLPHLTV EAMMVSA+LKL EK E ++E+V EILTALGL+SC++TRT LSGGQ Sbjct: 146 IMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQ 205 Query: 219 RKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLF 278 RKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK LAQGGR+IICTIHQPSAKLF Sbjct: 206 RKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLF 265 Query: 279 ELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLV 338 E+FD+LY+LSQGQC+++G V NL+PYL+ LGL+CPTYHNPADF++EVASGEYGD N L Sbjct: 266 EMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGEYGDLNPMLF 325 Query: 339 RAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTF 398 RAV+ G+C K+ EV P E D H+F+ S LTQFCILFKRTF Sbjct: 326 RAVQNGLCAMAEKKSSPEKNEVPAPCPPCPPEVDPIE---SHTFATSTLTQFCILFKRTF 382 Query: 399 LSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPT 458 LSI+RD+VLTHLR SH+ IG+LIGLLYL IG++A KV +N+G LFFSMLFLMFAALMPT Sbjct: 383 LSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTGCLFFSMLFLMFAALMPT 442 Query: 459 VLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVR 518 VLTFPLEM VF+REHLNYWYSLKAYYLAKTMADVPFQ++ PV YCSIVYWMT QP++ R Sbjct: 443 VLTFPLEMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSR 502 Query: 519 FVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYL 578 F+LF+AL T T+LVAQSLGLLIGAAS SLQVATFVGPVTAIPVLLFSGFFVSF TIPTYL Sbjct: 503 FLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYL 562 Query: 579 QWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFI 638 QW SY+SYVRYGFEGVIL+IYG++R DL C ++E C F++ ++ILR LDVE+AKLY+DF+ Sbjct: 563 QWSSYLSYVRYGFEGVILTIYGMERGDLTC-LEERCPFREPQSILRALDVEDAKLYMDFL 621 Query: 639 VLGIFFISLRLIAYFVLRYKIRAER 663 VLGIFF++LRL+AY VLRY++++ER Sbjct: 622 VLGIFFLALRLLAYLVLRYRVKSER 646 >gi|20143975 ATP-binding cassette, subfamily G, member 4 [Homo sapiens] Length = 646 Score = 922 bits (2383), Expect = 0.0 Identities = 459/625 (73%), Positives = 536/625 (85%), Gaps = 4/625 (0%) Query: 39 EATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLL 98 + E +L HLKKV+N++TEAQRFS LP+R+AV+IEF +LSYSV EGP WRK+GYKTLL Sbjct: 26 DGAEPPVLTTHLKKVENHITEAQRFSHLPKRSAVDIEFVELSYSVREGPCWRKRGYKTLL 85 Query: 99 KGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCY 158 K +SGKF EL+ IMGPSGAGKST MNILAGYRE+GMKG +L+NG PR+LR FRK+SCY Sbjct: 86 KCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCY 145 Query: 159 IMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQ 218 IMQDDMLLPHLTV EAMMVSA+LKL EK E ++E+V EILTALGL+SC++TRT LSGGQ Sbjct: 146 IMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQ 205 Query: 219 RKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLF 278 RKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK LAQGGR+IICTIHQPSAKLF Sbjct: 206 RKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLF 265 Query: 279 ELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLV 338 E+FD+LY+LSQGQC+++G V NL+PYL+ LGL+CPTYHNPADF++EVASGEYGD N L Sbjct: 266 EMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGEYGDLNPMLF 325 Query: 339 RAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTF 398 RAV+ G+C K+ EV P E D H+F+ S LTQFCILFKRTF Sbjct: 326 RAVQNGLCAMAEKKSSPEKNEVPAPCPPCPPEVDPIE---SHTFATSTLTQFCILFKRTF 382 Query: 399 LSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPT 458 LSI+RD+VLTHLR SH+ IG+LIGLLYL IG++A KV +N+G LFFSMLFLMFAALMPT Sbjct: 383 LSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTGCLFFSMLFLMFAALMPT 442 Query: 459 VLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVR 518 VLTFPLEM VF+REHLNYWYSLKAYYLAKTMADVPFQ++ PV YCSIVYWMT QP++ R Sbjct: 443 VLTFPLEMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSR 502 Query: 519 FVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYL 578 F+LF+AL T T+LVAQSLGLLIGAAS SLQVATFVGPVTAIPVLLFSGFFVSF TIPTYL Sbjct: 503 FLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYL 562 Query: 579 QWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFI 638 QW SY+SYVRYGFEGVIL+IYG++R DL C ++E C F++ ++ILR LDVE+AKLY+DF+ Sbjct: 563 QWSSYLSYVRYGFEGVILTIYGMERGDLTC-LEERCPFREPQSILRALDVEDAKLYMDFL 621 Query: 639 VLGIFFISLRLIAYFVLRYKIRAER 663 VLGIFF++LRL+AY VLRY++++ER Sbjct: 622 VLGIFFLALRLLAYLVLRYRVKSER 646 >gi|62526033 ATP-binding cassette, sub-family G, member 2 [Homo sapiens] Length = 655 Score = 261 bits (667), Expect = 1e-69 Identities = 163/530 (30%), Positives = 293/530 (55%), Gaps = 35/530 (6%) Query: 90 RKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRE-TGMKGAVLINGLPRD 148 RK K +L I+G G L AI+GP+G GKS+L+++LA ++ +G+ G VLING PR Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114 Query: 149 LRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEK--DEGRREMVKEILTALGLLSC 206 F+ S Y++QDD+++ LTV+E + SA L+L + + E + ++ LGL Sbjct: 115 AN-FKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKV 173 Query: 207 ANTRTGS-----LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQ 261 A+++ G+ +SGG+RKR +I +EL+ +P ++F DEPT+GLDS++ V+ L+K +++ Sbjct: 174 ADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSK 233 Query: 262 GGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADF 321 GR+II +IHQP +F+LFD L +L+ G+ ++ G + Y G +C Y+NPADF Sbjct: 234 QGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADF 293 Query: 322 VMEVASG-------------------EYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNP 362 +++ +G E Q+ L+ + E +S ++ AE++ Sbjct: 294 FLDIINGDSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKET--KAELHQ 351 Query: 363 FLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLI 422 ++ + E S++ S Q + KR+F +++ + + +I + +GL+I Sbjct: 352 LSGGEKKKKITVFKE--ISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVI 409 Query: 423 GLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKA 482 G +Y G+ N++ + + +G LFF F+++ L F +E +F+ E+++ +Y + + Sbjct: 410 GAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVEL-FVVEKKLFIHEYISGYYRVSS 468 Query: 483 YYLAKTMAD-VPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIG 541 Y+L K ++D +P +++ + + IVY+M A F + M + A S+ L I Sbjct: 469 YFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIA 528 Query: 542 AASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGF 591 A + + VAT + + + +++FSG V+ TI ++L W+ Y S RYGF Sbjct: 529 AGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGF 578 >gi|11967971 ATP-binding cassette sub-family G member 8 [Homo sapiens] Length = 673 Score = 226 bits (576), Expect = 5e-59 Identities = 160/624 (25%), Positives = 290/624 (46%), Gaps = 52/624 (8%) Query: 74 IEFRDLSYSVP---EGPWWRKKGYKTL--------------LKGISGKFNSGELVAIMGP 116 +E RDL+Y V + PW+ + + ++ +S K SG+++AI+G Sbjct: 47 LEVRDLNYQVDLASQVPWFEQLAQFKMPWTSPSCQNSCELGIQNLSFKVRSGQMLAIIGS 106 Query: 117 SGAGKSTLMNILAGYRETGM--KGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEA 174 SG G+++L++++ G G G + ING P + RK ++ Q + LLP+LTV+E Sbjct: 107 SGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKCVAHVRQHNQLLPNLTVRET 166 Query: 175 MMVSAHLKLQE--KDEGRREMVKEILTALGLLSCANTRTGS-----LSGGQRKRLAIALE 227 + A ++L R + V++++ L L CA+TR G+ LSGG+R+R++I ++ Sbjct: 167 LAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQ 226 Query: 228 LVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVL 287 L+ NP ++ DEPTSGLDS + +V + LA+G R ++ ++HQP + +F LFD + ++ Sbjct: 227 LLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLM 286 Query: 288 SQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCD 347 + G +Y G ++V Y +G CP Y NPADF +++ S D+ SR Sbjct: 287 TSGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDLTS---IDRRSREQELATREKAQ 343 Query: 348 SDHKRDLGGDAEVNPFLWH---RPSEEDSSSMEGCHSFSASCL----------TQFCILF 394 S L +++ FLW + +ED+ +CL QF L Sbjct: 344 SLAALFLEKVRDLDDFLWKAETKDLDEDTCVESSVTPLDTNCLPSPTKMPGAVQQFTTLI 403 Query: 395 KRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAA 454 +R + RD + + + IG LY G G+ + + LF + F Sbjct: 404 RRQISNDFRDLPTLLIHGAEACLMSMTIGFLYFGHGSIQLSFMDTAALLFMIGALIPFNV 463 Query: 455 LMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPS 514 ++ + E + E + Y+ Y+ AK + ++P + + Y YW+ + Sbjct: 464 ILDVISKCYSERAMLYYELEDGLYTTGPYFFAKILGELPEHCAYIIIYGMPTYWLANLRP 523 Query: 515 DAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTI 574 F+L L + + + L A + +A+F L GF ++ ++ Sbjct: 524 GLQPFLLHFLLVWLVVFCCRIMALAAAALLPTFHMASFFSNALYNSFYLAGGFMINLSSL 583 Query: 575 PTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLY 634 T W+S +S++R+ FEG++ + R + + IL +++++ LY Sbjct: 584 WTVPAWISKVSFLRWCFEGLMKIQF--SRRTYKMPLGNLTIAVSGDKILSVMELDSYPLY 641 Query: 635 -LDFIVLG-------IFFISLRLI 650 + IV+G ++++SLR I Sbjct: 642 AIYLIVIGLSGGFMVLYYVSLRFI 665 >gi|11967969 ATP-binding cassette sub-family G member 5 [Homo sapiens] Length = 651 Score = 209 bits (533), Expect = 5e-54 Identities = 160/614 (26%), Positives = 302/614 (49%), Gaps = 45/614 (7%) Query: 80 SYSVPEG--PWW-----RKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGY- 131 SYSV PWW R++ + +LK +S SG+++ I+G SG+GK+TL++ ++G Sbjct: 44 SYSVSHRVRPWWDITSCRQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRL 103 Query: 132 -RETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGR 190 R G V +NG F+ Y++Q D LL LTV+E + +A L ++ + G Sbjct: 104 GRAGTFLGEVYVNGRALRREQFQDCFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGS 163 Query: 191 -REMVKEILTALGLLSCA-----NTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 244 ++ V+ ++ L L A N G +S G+R+R++IA +L+ +P VM FDEPT+GL Sbjct: 164 FQKKVEAVMAELSLSHVADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGL 223 Query: 245 DSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPY 304 D + Q+V L+ LA+ R ++ TIHQP ++LF+LFD++ +LS G+ ++ G ++ + Sbjct: 224 DCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDF 283 Query: 305 LRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFL 364 D G CP + NP DF M++ S + + + + R M +S +K+ + Sbjct: 284 FNDCGYPCPEHSNPFDFYMDLTSVDTQSKEREIETSKRVQMIESAYKKSA---------I 334 Query: 365 WHRPSEEDSSSMEGCHSF---------SASCLTQFCILFKRTFLSIMRDSVLTHLRITSH 415 H+ + ++ M+ + S ++ +L +R +++R+ + R+ + Sbjct: 335 CHK-TLKNIERMKHLKTLPMVPFKTKDSPGVFSKLGVLLRRVTRNLVRNKLAVITRLLQN 393 Query: 416 IGIGLLIGLLYLGIGNEAKK--VLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREH 473 + +GL + L + + K + G L+ + + ++ V FP+ V +E Sbjct: 394 LIMGLFLLFFVLRVRSNVLKGAIQDRVGLLYQFVGATPYTGMLNAVNLFPVLRAVSDQES 453 Query: 474 LNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVA 533 + Y LA + +PF ++ + + S+ YW + RF F+A L+ Sbjct: 454 QDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHPEVARFGYFSAALLAPHLIG 513 Query: 534 QSLGL-LIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFE 592 + L L L+G V + V ++ VL+ SGF + +P + +SY ++ +Y E Sbjct: 514 EFLTLVLLGIVQNPNIVNSVVALLSIAGVLVGSGFLRNIQEMPIPFKIISYFTFQKYCSE 573 Query: 593 GVILS-IYGLD----REDLHCDIDETCHF-QKSEAILRELDVENAKLYLDFIVLGIFFIS 646 ++++ YGL+ ++ + C F Q + I + ++ ++F++L F + Sbjct: 574 ILVVNEFYGLNFTCGSSNVSVTTNPMCAFTQGIQFIEKTCPGATSRFTMNFLILYSFIPA 633 Query: 647 LRLIAYFVLRYKIR 660 L ++ V +KIR Sbjct: 634 LVILGIVV--FKIR 645 >gi|27881501 ATP-binding cassette, sub-family A, member 12 isoform b [Homo sapiens] Length = 2277 Score = 90.9 bits (224), Expect = 3e-18 Identities = 63/219 (28%), Positives = 112/219 (51%), Gaps = 6/219 (2%) Query: 75 EFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRET 134 E +DL+ V + G K + ++ F G + +++GP+GAGK+T +++L G Sbjct: 1020 EPKDLTVGVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGA 1079 Query: 135 GMKGAVLING--LPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGR-R 191 G + + G + DL RK MQ D+L +LT +E +++ +K+ + + Sbjct: 1080 SA-GTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKKQLH 1138 Query: 192 EMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ 251 E VK L GL S + R G+LSGG +++L+I++ L+ V+ DEP++G+D S Sbjct: 1139 EEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRS 1198 Query: 252 VVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQG 290 + ++ I+ T H A++ L D++ L QG Sbjct: 1199 IWDVISKNKTARTIILSTHHLDEAEV--LSDRIAFLEQG 1235 Score = 66.2 bits (160), Expect = 9e-11 Identities = 53/178 (29%), Positives = 86/178 (48%), Gaps = 7/178 (3%) Query: 98 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 157 + IS +GE ++G +GAGK+T+ +L G G +LI L S Sbjct: 1955 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTG-DIIPSSGNILIRNKTGSLGHVDSHSS 2013 Query: 158 ---YIMQDDMLLPHLTVQEAMMVSAHLK-LQEKDEGRREMVKEILTALGLLSCANTRTGS 213 Y Q+D L +TV+E + A + + EKD +E V ++L L L+ + T Sbjct: 2014 LVGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDI--KETVHKLLRRLHLMPFKDRATSM 2071 Query: 214 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 271 S G +++L+ AL L+ P ++ DEP+SG+D S + ++ Q S+I T H Sbjct: 2072 CSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSH 2129 >gi|30795238 ATP-binding cassette, sub-family A, member 12 isoform a [Homo sapiens] Length = 2595 Score = 90.9 bits (224), Expect = 3e-18 Identities = 63/219 (28%), Positives = 112/219 (51%), Gaps = 6/219 (2%) Query: 75 EFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRET 134 E +DL+ V + G K + ++ F G + +++GP+GAGK+T +++L G Sbjct: 1338 EPKDLTVGVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGA 1397 Query: 135 GMKGAVLING--LPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGR-R 191 G + + G + DL RK MQ D+L +LT +E +++ +K+ + + Sbjct: 1398 SA-GTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKKQLH 1456 Query: 192 EMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ 251 E VK L GL S + R G+LSGG +++L+I++ L+ V+ DEP++G+D S Sbjct: 1457 EEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRS 1516 Query: 252 VVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQG 290 + ++ I+ T H A++ L D++ L QG Sbjct: 1517 IWDVISKNKTARTIILSTHHLDEAEV--LSDRIAFLEQG 1553 Score = 66.2 bits (160), Expect = 9e-11 Identities = 53/178 (29%), Positives = 86/178 (48%), Gaps = 7/178 (3%) Query: 98 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 157 + IS +GE ++G +GAGK+T+ +L G G +LI L S Sbjct: 2273 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTG-DIIPSSGNILIRNKTGSLGHVDSHSS 2331 Query: 158 ---YIMQDDMLLPHLTVQEAMMVSAHLK-LQEKDEGRREMVKEILTALGLLSCANTRTGS 213 Y Q+D L +TV+E + A + + EKD +E V ++L L L+ + T Sbjct: 2332 LVGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDI--KETVHKLLRRLHLMPFKDRATSM 2389 Query: 214 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 271 S G +++L+ AL L+ P ++ DEP+SG+D S + ++ Q S+I T H Sbjct: 2390 CSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSH 2447 >gi|105990541 ATP-binding cassette, sub-family A member 4 [Homo sapiens] Length = 2273 Score = 90.1 bits (222), Expect = 6e-18 Identities = 63/194 (32%), Positives = 100/194 (51%), Gaps = 6/194 (3%) Query: 105 FNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLING--LPRDLRCFRKVSCYIMQD 162 F ++ A +G +GAGK+T ++IL G G VL+ G + L R+ Q Sbjct: 953 FYENQITAFLGHNGAGKTTTLSILTGLLPP-TSGTVLVGGRDIETSLDAVRQSLGMCPQH 1011 Query: 163 DMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRL 222 ++L HLTV E M+ A LK + ++E + EM + +L GL N LSGG +++L Sbjct: 1012 NILFHHLTVAEHMLFYAQLKGKSQEEAQLEM-EAMLEDTGLHHKRNEEAQDLSGGMQRKL 1070 Query: 223 AIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFD 282 ++A+ V + V+ DEPTSG+D S + L+ G I+ T H A L L D Sbjct: 1071 SVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADL--LGD 1128 Query: 283 QLYVLSQGQCVYRG 296 ++ +++QG+ G Sbjct: 1129 RIAIIAQGRLYCSG 1142 Score = 66.6 bits (161), Expect = 7e-11 Identities = 44/165 (26%), Positives = 85/165 (51%), Gaps = 2/165 (1%) Query: 108 GELVAIMGPSGAGKSTLMNILAGYRE-TGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLL 166 GE ++G +GAGK+T +L G T V + ++ + Y Q D + Sbjct: 1965 GECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAID 2024 Query: 167 PHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIAL 226 LT +E + + A L+ +E + + + +LGL A+ G+ SGG +++L+ A+ Sbjct: 2025 ELLTGREHLYLYARLRGVPAEEIEK-VANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAI 2083 Query: 227 ELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 271 L+ PP++ DEPT+G+D + + +++ + + GR+++ T H Sbjct: 2084 ALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAVVLTSH 2128 >gi|153792144 ATP-binding cassette, sub-family A, member 10 [Homo sapiens] Length = 1543 Score = 89.0 bits (219), Expect = 1e-17 Identities = 60/170 (35%), Positives = 92/170 (54%), Gaps = 4/170 (2%) Query: 91 KKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLIN---GLPR 147 K G L+GI G++ AI+G +GAGKSTL+NIL+G + A + N Sbjct: 403 KTGKVEALQGIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEIT 462 Query: 148 DLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCA 207 D+ RK + Q + LTV+E + V A +K + E +E VK I+ L + S Sbjct: 463 DMEEIRKNIGFCPQFNFQFDFLTVRENLRVFAKIKGIQPKEVEQE-VKRIIMELDMQSIQ 521 Query: 208 NTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 257 + LSGGQ+++L + + ++ +P V+ DEPT+GLD S +V SL+K Sbjct: 522 DIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEPTAGLDPFSRHRVWSLLK 571 Score = 66.2 bits (160), Expect = 9e-11 Identities = 51/190 (26%), Positives = 93/190 (48%), Gaps = 9/190 (4%) Query: 90 RKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDL 149 RKK K ++ +S GE++ ++G +GAGKST + ++ G + G V++ G + Sbjct: 1216 RKK--KIAIRNVSFCVKKGEVLGLLGHNGAGKSTSIKMITGCTKP-TAGVVVLQGSRASV 1272 Query: 150 RCFRKVSC----YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLS 205 R S Y Q++ L P LT++E + + A +K K++ + ++ AL L Sbjct: 1273 RQQHDNSLKFLGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAALS-ISRLVEALKLQE 1331 Query: 206 CANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQG-GR 264 +LS G +++L L ++ NP V+ DEP +G+D Q+ +++ + R Sbjct: 1332 QLKAPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQMWQILQATVKNKER 1391 Query: 265 SIICTIHQPS 274 + T H S Sbjct: 1392 GTLLTTHYMS 1401 >gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13 [Homo sapiens] Length = 5058 Score = 86.7 bits (213), Expect = 6e-17 Identities = 59/203 (29%), Positives = 108/203 (53%), Gaps = 6/203 (2%) Query: 92 KGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLING--LPRDL 149 +G+K +++ +S F ++ A++G +GAGK+T++++L G G ++ING L DL Sbjct: 3852 EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPP-TSGTIIINGKNLQTDL 3910 Query: 150 RCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMVKEILTALGLLSCAN 208 R Q D+LL +LTV+E +++ A +K Q + + V + L + L + Sbjct: 3911 SRVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELHQQVNQTLQDVDLTQHQH 3970 Query: 209 TRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIIC 268 +T +LSGG +++L++ + + + DEPTSG+D S + ++ +G I Sbjct: 3971 KQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFT 4030 Query: 269 TIHQPSAKLFELFDQLYVLSQGQ 291 T H A+ L D++ VL G+ Sbjct: 4031 THHLDEAE--ALSDRVAVLQHGR 4051 Score = 52.0 bits (123), Expect = 2e-06 Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 7/176 (3%) Query: 98 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLIN--GLPRDLRCFRKV 155 ++ IS GE ++G +GAGKST +L G A++ G DL Sbjct: 4737 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTA 4796 Query: 156 SC---YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTG 212 Y Q D L LT E + L+ + + E+ +++ L L + A+ Sbjct: 4797 GVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPR-QCIPEVAGDLIRRLHLEAHADKPVA 4855 Query: 213 SLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS-CFQVVSLMKGLAQGGRSII 267 + SGG +++L+ AL LV P ++ DEP+SG+D S + ++MK + +G +++ Sbjct: 4856 TYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVL 4911 >gi|21536376 ATP-binding cassette, sub-family A member 1 [Homo sapiens] Length = 2261 Score = 85.5 bits (210), Expect = 1e-16 Identities = 59/202 (29%), Positives = 102/202 (50%), Gaps = 3/202 (1%) Query: 91 KKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAG-YRETGMKGAVLINGLPRDL 149 + G K + G++ F G++ + +G +GAGK+T M+IL G + T +L + ++ Sbjct: 909 RDGMKVAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEM 968 Query: 150 RCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANT 209 R+ Q ++L LTV+E + A LK + + EM + L S + Sbjct: 969 STIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKS 1028 Query: 210 RTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICT 269 +T LSGG +++L++AL V V+ DEPT+G+D S + L+ QG I+ T Sbjct: 1029 KTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILST 1088 Query: 270 IHQPSAKLFELFDQLYVLSQGQ 291 H A + L D++ ++S G+ Sbjct: 1089 HHMDEADV--LGDRIAIISHGK 1108 Score = 71.2 bits (173), Expect = 3e-12 Identities = 49/166 (29%), Positives = 86/166 (51%), Gaps = 4/166 (2%) Query: 108 GELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLI-NGLPRDLRCFRKVSCYIMQDDMLL 166 GE ++G +GAGKS+ +L G A L N + ++ + Y Q D + Sbjct: 1939 GECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAIT 1998 Query: 167 PHLTVQEAMMVSAHLK-LQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIA 225 LT +E + A L+ + EK+ G+ + + + LGL+ G+ SGG +++L+ A Sbjct: 1999 ELLTGREHVEFFALLRGVPEKEVGK--VGEWAIRKLGLVKYGEKYAGNYSGGNKRKLSTA 2056 Query: 226 LELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 271 + L+ PPV+F DEPT+G+D + + + + + GRS++ T H Sbjct: 2057 MALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSH 2102 >gi|116734710 ATP-binding cassette, sub-family A member 3 [Homo sapiens] Length = 1704 Score = 82.4 bits (202), Expect = 1e-15 Identities = 60/187 (32%), Positives = 104/187 (55%), Gaps = 8/187 (4%) Query: 108 GELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLING--LPRDLRCFRKVSCYIMQDDML 165 G++ ++G +GAGK+T +++L G G I+G + +D+ RK Q D+L Sbjct: 559 GQITVLLGHNGAGKTTTLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDIL 617 Query: 166 LPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIA 225 +LTV E + A LK + + E VK++L +GL N+R+ LSGG R++L+I Sbjct: 618 FDNLTVAEHLYFYAQLKGLSRQKCPEE-VKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIG 676 Query: 226 LELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH-QPSAKLFELFDQL 284 + L+ V+ DEPTSG+D+ S + L++ + R+I+ T H A L L D++ Sbjct: 677 IALIAGSKVLILDEPTSGMDAISRRAIWDLLQ-RQKSDRTIVLTTHFMDEADL--LGDRI 733 Query: 285 YVLSQGQ 291 ++++G+ Sbjct: 734 AIMAKGE 740 Score = 75.5 bits (184), Expect = 1e-13 Identities = 56/187 (29%), Positives = 96/187 (51%), Gaps = 7/187 (3%) Query: 108 GELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLING--LPRDLRCFRKVSCYIMQDDML 165 GE ++G +GAGK+T +L G E+ G + G + D+ R+ Y Q D L Sbjct: 1409 GECFGLLGFNGAGKTTTFKMLTG-EESLTSGDAFVGGHRISSDVGKVRQRIGYCPQFDAL 1467 Query: 166 LPHLTVQEAMMVSAHLK-LQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAI 224 L H+T +E +++ A L+ + E+ G V+ L L L AN + SGG +++L+ Sbjct: 1468 LDHMTGREMLVMYARLRGIPERHIGA--CVENTLRGLLLEPHANKLVRTYSGGNKRKLST 1525 Query: 225 ALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQL 284 + L+ P V+F DEP++G+D + + + + G++II T H + L +L Sbjct: 1526 GIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIITSHS-MEECEALCTRL 1584 Query: 285 YVLSQGQ 291 ++ QGQ Sbjct: 1585 AIMVQGQ 1591 >gi|27436953 ATP-binding cassette, sub-family A, member 6 [Homo sapiens] Length = 1617 Score = 82.0 bits (201), Expect = 2e-15 Identities = 64/205 (31%), Positives = 104/205 (50%), Gaps = 8/205 (3%) Query: 91 KKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLP---- 146 K G LKG+ G++ AI+G SGAGKS+L+NIL G +G+V I Sbjct: 490 KSGKVEALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGL-SVPTEGSVTIYNKNLSEM 548 Query: 147 RDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSC 206 +DL RK++ Q ++ LTV+E + + A +K E +E V+ IL L + + Sbjct: 549 QDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQE-VQRILLELDMQNI 607 Query: 207 ANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSI 266 + LS GQ+++L + ++ +P ++ DEPT+GLD S QV SL++ + Sbjct: 608 QDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRERRADHVIL 667 Query: 267 ICTIHQPSAKLFELFDQLYVLSQGQ 291 T A + L D+ ++S G+ Sbjct: 668 FSTQSMDEADI--LADRKVIMSNGR 690 Score = 73.2 bits (178), Expect = 7e-13 Identities = 56/212 (26%), Positives = 106/212 (50%), Gaps = 8/212 (3%) Query: 91 KKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLR 150 K+ K + IS GE++ ++GP+GAGKS+ + +++G + G V + G L Sbjct: 1296 KRKKKIAARNISFCVQEGEILGLLGPNGAGKSSSIRMISGITKP-TAGEVELKGCSSVLG 1354 Query: 151 CFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTR 210 Y Q+++L P LT++E + V A +K K + R + + +++A L N Sbjct: 1355 HLG----YCPQENVLWPMLTLREHLEVYAAVKGLRKADARLAIAR-LVSAFKLHEQLNVP 1409 Query: 211 TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQG-GRSIICT 269 L+ G ++L L L+ N PV+ DEP++G+D Q+ ++ + + R ++ T Sbjct: 1410 VQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLT 1469 Query: 270 IHQPSAKLFELFDQLYVLSQGQCVYRGKVCNL 301 H A+ L D++ ++ G+ G + +L Sbjct: 1470 THN-LAEAEALCDRVAIMVSGRLRCIGSIQHL 1500 >gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo sapiens] Length = 1642 Score = 81.6 bits (200), Expect = 2e-15 Identities = 64/211 (30%), Positives = 109/211 (51%), Gaps = 9/211 (4%) Query: 89 WRKKGYKT-LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPR 147 +RKKG L+ +S G++ A++G SG GKSTLMNIL G A + Sbjct: 487 YRKKGENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVS 546 Query: 148 DLRCF---RKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLL 204 ++ RK+ Q D+ LTV+E + + A +K + +E V+++L L + Sbjct: 547 EIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQE-VQKVLLDLDMQ 605 Query: 205 SCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGR 264 + + + LSGGQ+++L++ + ++ NP ++ DEPT+G+D S V +L+K Sbjct: 606 TIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRV 665 Query: 265 SIICTIHQPSAKLFELFDQLYVLSQG--QCV 293 ++ T A + L D+ V+SQG +CV Sbjct: 666 TVFSTHFMDEADI--LADRKAVISQGMLKCV 694 Score = 69.3 bits (168), Expect = 1e-11 Identities = 49/162 (30%), Positives = 77/162 (47%), Gaps = 13/162 (8%) Query: 91 KKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRD-- 148 +K K K IS GE++ ++GP+GAGKST++NIL G E G V + + Sbjct: 1309 RKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEP-TSGQVFLGDYSSETS 1367 Query: 149 -----LRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGL 203 L+C Y Q + L P T+QE + +K + +E++ I AL L Sbjct: 1368 EDDDSLKCMG----YCPQINPLWPDTTLQEHFEIYGAVKGMSASD-MKEVISRITHALDL 1422 Query: 204 LSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 245 L G +++L AL ++ NP + DEP++G+D Sbjct: 1423 KEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 1464 >gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo sapiens] Length = 1642 Score = 81.6 bits (200), Expect = 2e-15 Identities = 64/211 (30%), Positives = 109/211 (51%), Gaps = 9/211 (4%) Query: 89 WRKKGYKT-LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPR 147 +RKKG L+ +S G++ A++G SG GKSTLMNIL G A + Sbjct: 487 YRKKGENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVS 546 Query: 148 DLRCF---RKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLL 204 ++ RK+ Q D+ LTV+E + + A +K + +E V+++L L + Sbjct: 547 EIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQE-VQKVLLDLDMQ 605 Query: 205 SCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGR 264 + + + LSGGQ+++L++ + ++ NP ++ DEPT+G+D S V +L+K Sbjct: 606 TIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRV 665 Query: 265 SIICTIHQPSAKLFELFDQLYVLSQG--QCV 293 ++ T A + L D+ V+SQG +CV Sbjct: 666 TVFSTHFMDEADI--LADRKAVISQGMLKCV 694 Score = 69.3 bits (168), Expect = 1e-11 Identities = 49/162 (30%), Positives = 77/162 (47%), Gaps = 13/162 (8%) Query: 91 KKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRD-- 148 +K K K IS GE++ ++GP+GAGKST++NIL G E G V + + Sbjct: 1309 RKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEP-TSGQVFLGDYSSETS 1367 Query: 149 -----LRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGL 203 L+C Y Q + L P T+QE + +K + +E++ I AL L Sbjct: 1368 EDDDSLKCMG----YCPQINPLWPDTTLQEHFEIYGAVKGMSASD-MKEVISRITHALDL 1422 Query: 204 LSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 245 L G +++L AL ++ NP + DEP++G+D Sbjct: 1423 KEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 1464 >gi|9961250 ATP-binding cassette, subfamily B, member 4 isoform B [Homo sapiens] Length = 1286 Score = 80.9 bits (198), Expect = 4e-15 Identities = 66/232 (28%), Positives = 114/232 (49%), Gaps = 26/232 (11%) Query: 73 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 132 N+EF D+ +S P + +LKG++ K SG+ VA++G SG GKST + ++ Sbjct: 393 NLEFNDVHFSYPS------RANVKILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLY 446 Query: 133 ETGMKGAVLINGLPRDLRCF-----RKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQE-- 185 + +G + I+G +D+R F R++ + Q+ +L + ++ + E Sbjct: 447 DPD-EGTINIDG--QDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIK 503 Query: 186 ---KDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTS 242 K+ E + ++ L R LSGGQ++R+AIA LV NP ++ DE TS Sbjct: 504 KAVKEANAYEFIMKLPQKFDTL--VGERGAQLSGGQKQRIAIARALVRNPKILLLDEATS 561 Query: 243 GLDSASCFQVVSLMKGLAQGGRSIICTIHQPS----AKLFELFDQLYVLSQG 290 LD+ S +V + + A+ GR+ I H+ S A + F+ ++ QG Sbjct: 562 ALDTESEAEVQAAL-DKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQG 612 Score = 58.5 bits (140), Expect = 2e-08 Identities = 60/248 (24%), Positives = 112/248 (45%), Gaps = 31/248 (12%) Query: 67 PRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMN 126 P + NI F ++ ++ P + +L+G+S + G+ +A++G SG GKST++ Sbjct: 1027 PDKFEGNITFNEVVFNYPT------RANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQ 1080 Query: 127 ILAGYRETGMKGAVLIN----------GLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMM 176 +L + + + G V ++ +++ R + Q+ +L ++ E + Sbjct: 1081 LLERFYDP-LAGTVFVDFGFQLLDGQEAKKLNVQWLRAQLGIVSQEPILFD-CSIAENIA 1138 Query: 177 VSAHLKLQEKDE----GRREMVKEILTALGLLSCANTRTGS----LSGGQRKRLAIALEL 228 + ++ +DE + + + L TR G LSGGQ++R+AIA L Sbjct: 1139 YGDNSRVVSQDEIVSAAKAANIHPFIETLP--HKYETRVGDKGTQLSGGQKQRIAIARAL 1196 Query: 229 VNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLS 288 + P ++ DE TS LD+ S +VV A+ GR+ I H+ S + D + V Sbjct: 1197 IRQPQILLLDEATSALDTES-EKVVQEALDKAREGRTCIVIAHRLST--IQNADLIVVFQ 1253 Query: 289 QGQCVYRG 296 G+ G Sbjct: 1254 NGRVKEHG 1261 >gi|9961252 ATP-binding cassette, subfamily B, member 4 isoform C [Homo sapiens] Length = 1232 Score = 80.9 bits (198), Expect = 4e-15 Identities = 66/232 (28%), Positives = 114/232 (49%), Gaps = 26/232 (11%) Query: 73 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 132 N+EF D+ +S P + +LKG++ K SG+ VA++G SG GKST + ++ Sbjct: 393 NLEFNDVHFSYPS------RANVKILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLY 446 Query: 133 ETGMKGAVLINGLPRDLRCF-----RKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQE-- 185 + +G + I+G +D+R F R++ + Q+ +L + ++ + E Sbjct: 447 DPD-EGTINIDG--QDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIK 503 Query: 186 ---KDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTS 242 K+ E + ++ L R LSGGQ++R+AIA LV NP ++ DE TS Sbjct: 504 KAVKEANAYEFIMKLPQKFDTL--VGERGAQLSGGQKQRIAIARALVRNPKILLLDEATS 561 Query: 243 GLDSASCFQVVSLMKGLAQGGRSIICTIHQPS----AKLFELFDQLYVLSQG 290 LD+ S +V + + A+ GR+ I H+ S A + F+ ++ QG Sbjct: 562 ALDTESEAEVQAAL-DKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQG 612 Score = 65.5 bits (158), Expect = 2e-10 Identities = 62/240 (25%), Positives = 114/240 (47%), Gaps = 22/240 (9%) Query: 67 PRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMN 126 P + NI F ++ ++ P + +L+G+S + G+ +A++G SG GKST++ Sbjct: 980 PDKFEGNITFNEVVFNYPT------RANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQ 1033 Query: 127 ILAGYRETGMKGAVLINGLP-RDLRC-FRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQ 184 +L + + + G VL++G + L + + I+ + +L ++ E + + ++ Sbjct: 1034 LLERFYDP-LAGTVLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVV 1092 Query: 185 EKDE----GRREMVKEILTALGLLSCANTRTGS----LSGGQRKRLAIALELVNNPPVMF 236 +DE + + + L TR G LSGGQ++R+AIA L+ P ++ Sbjct: 1093 SQDEIVSAAKAANIHPFIETLP--HKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILL 1150 Query: 237 FDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRG 296 DE TS LD+ S +VV A+ GR+ I H+ S + D + V G+ G Sbjct: 1151 LDEATSALDTES-EKVVQEALDKAREGRTCIVIAHRLST--IQNADLIVVFQNGRVKEHG 1207 >gi|4505771 ATP-binding cassette, subfamily B, member 4 isoform A [Homo sapiens] Length = 1279 Score = 80.9 bits (198), Expect = 4e-15 Identities = 66/232 (28%), Positives = 114/232 (49%), Gaps = 26/232 (11%) Query: 73 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 132 N+EF D+ +S P + +LKG++ K SG+ VA++G SG GKST + ++ Sbjct: 393 NLEFNDVHFSYPS------RANVKILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLY 446 Query: 133 ETGMKGAVLINGLPRDLRCF-----RKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQE-- 185 + +G + I+G +D+R F R++ + Q+ +L + ++ + E Sbjct: 447 DPD-EGTINIDG--QDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIK 503 Query: 186 ---KDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTS 242 K+ E + ++ L R LSGGQ++R+AIA LV NP ++ DE TS Sbjct: 504 KAVKEANAYEFIMKLPQKFDTL--VGERGAQLSGGQKQRIAIARALVRNPKILLLDEATS 561 Query: 243 GLDSASCFQVVSLMKGLAQGGRSIICTIHQPS----AKLFELFDQLYVLSQG 290 LD+ S +V + + A+ GR+ I H+ S A + F+ ++ QG Sbjct: 562 ALDTESEAEVQAAL-DKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQG 612 Score = 65.5 bits (158), Expect = 2e-10 Identities = 62/240 (25%), Positives = 114/240 (47%), Gaps = 22/240 (9%) Query: 67 PRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMN 126 P + NI F ++ ++ P + +L+G+S + G+ +A++G SG GKST++ Sbjct: 1027 PDKFEGNITFNEVVFNYPT------RANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQ 1080 Query: 127 ILAGYRETGMKGAVLINGLP-RDLRC-FRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQ 184 +L + + + G VL++G + L + + I+ + +L ++ E + + ++ Sbjct: 1081 LLERFYDP-LAGTVLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVV 1139 Query: 185 EKDE----GRREMVKEILTALGLLSCANTRTGS----LSGGQRKRLAIALELVNNPPVMF 236 +DE + + + L TR G LSGGQ++R+AIA L+ P ++ Sbjct: 1140 SQDEIVSAAKAANIHPFIETLP--HKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILL 1197 Query: 237 FDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRG 296 DE TS LD+ S +VV A+ GR+ I H+ S + D + V G+ G Sbjct: 1198 LDEATSALDTES-EKVVQEALDKAREGRTCIVIAHRLST--IQNADLIVVFQNGRVKEHG 1254 >gi|45446740 ATP-binding cassette, sub-family A, member 2 isoform a [Homo sapiens] Length = 2436 Score = 80.9 bits (198), Expect = 4e-15 Identities = 54/167 (32%), Positives = 90/167 (53%), Gaps = 6/167 (3%) Query: 108 GELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLING--LPRDLRCFRKVSCYIMQDDML 165 GE ++G +GAGK++ +L G T G +NG + ++L ++ Y Q D L Sbjct: 2081 GECFGLLGVNGAGKTSTFKMLTGDEST-TGGEAFVNGHSVLKELLQVQQSLGYCPQCDAL 2139 Query: 166 LPHLTVQEAMMVSAHLK-LQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAI 224 LT +E + + L+ + KDE R +VK L L L A+ G+ SGG +++L+ Sbjct: 2140 FDELTAREHLQLYTRLRGISWKDEAR--VVKWALEKLELTKYADKPAGTYSGGNKRKLST 2197 Query: 225 ALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 271 A+ L+ P +F DEPT+G+D + + +L+ L + GRS++ T H Sbjct: 2198 AIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSH 2244 Score = 79.3 bits (194), Expect = 1e-14 Identities = 57/202 (28%), Positives = 103/202 (50%), Gaps = 4/202 (1%) Query: 91 KKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAG-YRETGMKGAVLINGLPRDL 149 K K L +S ++V+ +G +GAGK+T M+IL G + T + + + ++ Sbjct: 1001 KDDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEM 1060 Query: 150 RCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANT 209 RK Q ++L LTV+E + + LK ++E RREM K ++ L L + ++ Sbjct: 1061 DEIRKNLGMCPQHNVLFDRLTVEEHLWFYSRLKSMAQEEIRREMDK-MIEDLELSNKRHS 1119 Query: 210 RTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICT 269 +LSGG +++L++A+ V + DEPT+G+D + + L+ G ++ T Sbjct: 1120 LVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLST 1179 Query: 270 IHQPSAKLFELFDQLYVLSQGQ 291 H A L L D++ ++S G+ Sbjct: 1180 HHMDEADL--LGDRIAIISHGK 1199 >gi|47078218 ATP-binding cassette, sub-family A, member 2 isoform b [Homo sapiens] Length = 2466 Score = 80.9 bits (198), Expect = 4e-15 Identities = 54/167 (32%), Positives = 90/167 (53%), Gaps = 6/167 (3%) Query: 108 GELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLING--LPRDLRCFRKVSCYIMQDDML 165 GE ++G +GAGK++ +L G T G +NG + ++L ++ Y Q D L Sbjct: 2111 GECFGLLGVNGAGKTSTFKMLTGDEST-TGGEAFVNGHSVLKELLQVQQSLGYCPQCDAL 2169 Query: 166 LPHLTVQEAMMVSAHLK-LQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAI 224 LT +E + + L+ + KDE R +VK L L L A+ G+ SGG +++L+ Sbjct: 2170 FDELTAREHLQLYTRLRGISWKDEAR--VVKWALEKLELTKYADKPAGTYSGGNKRKLST 2227 Query: 225 ALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 271 A+ L+ P +F DEPT+G+D + + +L+ L + GRS++ T H Sbjct: 2228 AIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSH 2274 Score = 79.3 bits (194), Expect = 1e-14 Identities = 57/202 (28%), Positives = 103/202 (50%), Gaps = 4/202 (1%) Query: 91 KKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAG-YRETGMKGAVLINGLPRDL 149 K K L +S ++V+ +G +GAGK+T M+IL G + T + + + ++ Sbjct: 1031 KDDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEM 1090 Query: 150 RCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANT 209 RK Q ++L LTV+E + + LK ++E RREM K ++ L L + ++ Sbjct: 1091 DEIRKNLGMCPQHNVLFDRLTVEEHLWFYSRLKSMAQEEIRREMDK-MIEDLELSNKRHS 1149 Query: 210 RTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICT 269 +LSGG +++L++A+ V + DEPT+G+D + + L+ G ++ T Sbjct: 1150 LVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLST 1209 Query: 270 IHQPSAKLFELFDQLYVLSQGQ 291 H A L L D++ ++S G+ Sbjct: 1210 HHMDEADL--LGDRIAIISHGK 1229 >gi|150417984 ATP-binding cassette, sub-family A, member 7 [Homo sapiens] Length = 2146 Score = 80.9 bits (198), Expect = 4e-15 Identities = 65/227 (28%), Positives = 111/227 (48%), Gaps = 13/227 (5%) Query: 67 PRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMN 126 P + + R L P P + L+G+S F G + A +G +GAGK+T ++ Sbjct: 800 PPGLSPGVSVRSLEKRFPGSP-------QPALRGLSLDFYQGHITAFLGHNGAGKTTTLS 852 Query: 127 ILAG-YRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLK-LQ 184 IL+G + +G +L + + + R Q ++L LTV E + LK L Sbjct: 853 ILSGLFPPSGGSAFILGHDVRSSMAAIRPHLGVCPQYNVLFDMLTVDEHVWFYGRLKGLS 912 Query: 185 EKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 244 G + +L +GL+S + +T LSGG +++L++A+ V V+ DEPT+G+ Sbjct: 913 AAVVGPEQ--DRLLQDVGLVSKQSVQTRHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGV 970 Query: 245 DSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQ 291 D AS + L+ +G I+ T H A+L L D++ V++ G+ Sbjct: 971 DPASRRGIWELLLKYREGRTLILSTHHLDEAEL--LGDRVAVVAGGR 1015 Score = 69.7 bits (169), Expect = 8e-12 Identities = 49/165 (29%), Positives = 85/165 (51%), Gaps = 2/165 (1%) Query: 108 GELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLI-NGLPRDLRCFRKVSCYIMQDDMLL 166 GE ++G +GAGK++ ++ G AVL + + R+ Y Q D + Sbjct: 1820 GECFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCPQSDAIF 1879 Query: 167 PHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIAL 226 LT +E + + A L+ + + + L LGL A+ G+ SGG +++LA AL Sbjct: 1880 ELLTGREHLELLARLRGVPEAQVA-QTAGSGLARLGLSWYADRPAGTYSGGNKRKLATAL 1938 Query: 227 ELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIH 271 LV +P V+F DEPT+G+D ++ + + + + + GRS++ T H Sbjct: 1939 ALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGRSVMLTSH 1983 >gi|9955968 ATP-binding cassette, sub-family B (MDR/TAP), member 9 isoform 2 [Homo sapiens] Length = 723 Score = 80.1 bits (196), Expect = 6e-15 Identities = 69/263 (26%), Positives = 122/263 (46%), Gaps = 42/263 (15%) Query: 53 VDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVA 112 +D T S P ++F +++++ +R + + +L+ +S + G++ A Sbjct: 440 IDRQPTMVHDGSLAPDHLEGRVDFENVTFT------YRTRPHTQVLQNVSFSLSPGKVTA 493 Query: 113 IMGPSGAGKSTLMNILAGYRETGMKGAVLINGLP---RDLRCFRKVSCYIMQDDML---- 165 ++GPSG+GKS+ +NIL + G VL++G P D + +V + Q+ +L Sbjct: 494 LVGPSGSGKSSCVNILENFYPLE-GGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARS 552 Query: 166 --------LP----HLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGS 213 LP + V+ A +AH + E +G E + Sbjct: 553 ITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGE-------------KGAQ 599 Query: 214 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQP 273 LSGGQ++R+A+A LV NPPV+ DE TS LD+ S + + + G Q +++ H+ Sbjct: 600 LSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQ-KHTVLIIAHRL 658 Query: 274 SAKLFELFDQLYVLSQGQCVYRG 296 S E + VL +G+ V +G Sbjct: 659 ST--VEHAHLIVVLDKGRVVQQG 679 >gi|9955966 ATP-binding cassette, sub-family B (MDR/TAP), member 9 isoform 1 [Homo sapiens] Length = 766 Score = 80.1 bits (196), Expect = 6e-15 Identities = 69/263 (26%), Positives = 122/263 (46%), Gaps = 42/263 (15%) Query: 53 VDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVA 112 +D T S P ++F +++++ +R + + +L+ +S + G++ A Sbjct: 483 IDRQPTMVHDGSLAPDHLEGRVDFENVTFT------YRTRPHTQVLQNVSFSLSPGKVTA 536 Query: 113 IMGPSGAGKSTLMNILAGYRETGMKGAVLINGLP---RDLRCFRKVSCYIMQDDML---- 165 ++GPSG+GKS+ +NIL + G VL++G P D + +V + Q+ +L Sbjct: 537 LVGPSGSGKSSCVNILENFYPLE-GGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARS 595 Query: 166 --------LP----HLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGS 213 LP + V+ A +AH + E +G E + Sbjct: 596 ITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGE-------------KGAQ 642 Query: 214 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQP 273 LSGGQ++R+A+A LV NPPV+ DE TS LD+ S + + + G Q +++ H+ Sbjct: 643 LSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQ-KHTVLIIAHRL 701 Query: 274 SAKLFELFDQLYVLSQGQCVYRG 296 S E + VL +G+ V +G Sbjct: 702 ST--VEHAHLIVVLDKGRVVQQG 722 >gi|45243524 ATP-binding cassette, sub-family B (MDR/TAP), member 9 isoform 1 [Homo sapiens] Length = 766 Score = 80.1 bits (196), Expect = 6e-15 Identities = 69/263 (26%), Positives = 122/263 (46%), Gaps = 42/263 (15%) Query: 53 VDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVA 112 +D T S P ++F +++++ +R + + +L+ +S + G++ A Sbjct: 483 IDRQPTMVHDGSLAPDHLEGRVDFENVTFT------YRTRPHTQVLQNVSFSLSPGKVTA 536 Query: 113 IMGPSGAGKSTLMNILAGYRETGMKGAVLINGLP---RDLRCFRKVSCYIMQDDML---- 165 ++GPSG+GKS+ +NIL + G VL++G P D + +V + Q+ +L Sbjct: 537 LVGPSGSGKSSCVNILENFYPLE-GGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARS 595 Query: 166 --------LP----HLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGS 213 LP + V+ A +AH + E +G E + Sbjct: 596 ITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGE-------------KGAQ 642 Query: 214 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQP 273 LSGGQ++R+A+A LV NPPV+ DE TS LD+ S + + + G Q +++ H+ Sbjct: 643 LSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQ-KHTVLIIAHRL 701 Query: 274 SAKLFELFDQLYVLSQGQCVYRG 296 S E + VL +G+ V +G Sbjct: 702 ST--VEHAHLIVVLDKGRVVQQG 722 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.138 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,325,043 Number of Sequences: 37866 Number of extensions: 1002184 Number of successful extensions: 3230 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 78 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 2946 Number of HSP's gapped (non-prelim): 182 length of query: 663 length of database: 18,247,518 effective HSP length: 109 effective length of query: 554 effective length of database: 14,120,124 effective search space: 7822548696 effective search space used: 7822548696 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.