Search of human proteins with 46370095

Search of human proteins with 46370095

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46370095 adaptor-related protein complex 3, mu 1 subunit
[Homo sapiens]
         (418 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6912240 adaptor-related protein complex 3, mu 1 subunit [Homo...   840   0.0  
gi|46370095 adaptor-related protein complex 3, mu 1 subunit [Hom...   840   0.0  
gi|197209857 adaptor-related protein complex 3, mu 2 subunit [Ho...   741   0.0  
gi|5803000 adaptor-related protein complex 3, mu 2 subunit [Homo...   741   0.0  
gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo...   204   2e-52
gi|14210504 adaptor-related protein complex 1, mu 1 subunit isof...   186   4e-47
gi|194473724 adaptor-related protein complex 1, mu 1 subunit iso...   177   2e-44
gi|14917109 adaptor-related protein complex 2, mu 1 subunit isof...   162   5e-40
gi|68799814 adaptor-related protein complex 2, mu 1 subunit isof...   161   1e-39
gi|14917111 adaptor-related protein complex 4, mu 1 subunit [Hom...   111   1e-24
gi|88703051 adaptor-related protein complex 1, sigma 3 subunit [...    38   0.020
gi|189409104 adaptor-related protein complex 4, sigma 1 subunit ...    37   0.043
gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [H...    36   0.057
gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [H...    35   0.13 
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]    31   1.8  
gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens]      31   1.8  
gi|26787993 stonin 1 [Homo sapiens]                                    30   3.1  
gi|29553944 STON1-GTF2A1L protein [Homo sapiens]                       30   3.1  
gi|4757768 Rho GDP dissociation inhibitor (GDI) alpha [Homo sapi...    30   5.3  
gi|70906430 adaptor-related protein complex 2, sigma 1 subunit i...    30   5.3  
gi|4506585 replication protein A2, 32kDa [Homo sapiens]                29   6.9  

>gi|6912240 adaptor-related protein complex 3, mu 1 subunit [Homo
           sapiens]
          Length = 418

 Score =  840 bits (2169), Expect = 0.0
 Identities = 418/418 (100%), Positives = 418/418 (100%)

Query: 1   MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY 60
           MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY
Sbjct: 1   MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY 60

Query: 61  RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG 120
           RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG
Sbjct: 61  RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG 120

Query: 121 FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAY 180
           FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAY
Sbjct: 121 FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAY 180

Query: 181 FDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFK 240
           FDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFK
Sbjct: 181 FDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFK 240

Query: 241 RWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQN 300
           RWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQN
Sbjct: 241 RWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQN 300

Query: 301 MGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKITPQKLPSLKGLVNL 360
           MGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKITPQKLPSLKGLVNL
Sbjct: 301 MGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKITPQKLPSLKGLVNL 360

Query: 361 QSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKYVTKAGKFQVRT 418
           QSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKYVTKAGKFQVRT
Sbjct: 361 QSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKYVTKAGKFQVRT 418


>gi|46370095 adaptor-related protein complex 3, mu 1 subunit [Homo
           sapiens]
          Length = 418

 Score =  840 bits (2169), Expect = 0.0
 Identities = 418/418 (100%), Positives = 418/418 (100%)

Query: 1   MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY 60
           MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY
Sbjct: 1   MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY 60

Query: 61  RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG 120
           RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG
Sbjct: 61  RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG 120

Query: 121 FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAY 180
           FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAY
Sbjct: 121 FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAY 180

Query: 181 FDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFK 240
           FDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFK
Sbjct: 181 FDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFK 240

Query: 241 RWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQN 300
           RWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQN
Sbjct: 241 RWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQN 300

Query: 301 MGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKITPQKLPSLKGLVNL 360
           MGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKITPQKLPSLKGLVNL
Sbjct: 301 MGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKITPQKLPSLKGLVNL 360

Query: 361 QSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKYVTKAGKFQVRT 418
           QSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKYVTKAGKFQVRT
Sbjct: 361 QSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKYVTKAGKFQVRT 418


>gi|197209857 adaptor-related protein complex 3, mu 2 subunit [Homo
           sapiens]
          Length = 418

 Score =  741 bits (1914), Expect = 0.0
 Identities = 352/418 (84%), Positives = 396/418 (94%)

Query: 1   MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY 60
           MIHSLFLIN SGDIFLEKHWKSVVS+SVCDYFFEAQE+A + ENVPPVI TPHHYL+S+Y
Sbjct: 1   MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY 60

Query: 61  RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG 120
           R K+FFV+VIQTEVPPLFVIEFLHRV DTFQDYFG CSE  IKDNVV+VYE+LEEMLDNG
Sbjct: 61  RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG 120

Query: 121 FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAY 180
           FPLATESNILKELIKPPTILR+VVN+ITGS+NVGD LPTGQLS +PWRR GVKYTNNEAY
Sbjct: 121 FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY 180

Query: 181 FDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFK 240
           FDV+EEIDAIIDKSGST+ AEIQGVIDAC+KL+GMPDL+LSFMNPRLLDDVSFHPC+RFK
Sbjct: 181 FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFK 240

Query: 241 RWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQN 300
           RWESER+LSFIPPDGNFRL+SY VS+QNLVAIPVYVKH+ISF+++SS GRF+IT+GPKQ 
Sbjct: 241 RWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQT 300

Query: 301 MGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKITPQKLPSLKGLVNL 360
           MGKTIEG+TVT  MPK VLNM+LTP+QG++TFDPVTK+L+WDVGKI PQKLPSLKG ++L
Sbjct: 301 MGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSL 360

Query: 361 QSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKYVTKAGKFQVRT 418
           Q+GA KP+ENP++N+QFKIQQLAISGLKVNRLDMYGEKYKPFKG+KY+TKAGKFQVRT
Sbjct: 361 QAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT 418


>gi|5803000 adaptor-related protein complex 3, mu 2 subunit [Homo
           sapiens]
          Length = 418

 Score =  741 bits (1914), Expect = 0.0
 Identities = 352/418 (84%), Positives = 396/418 (94%)

Query: 1   MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY 60
           MIHSLFLIN SGDIFLEKHWKSVVS+SVCDYFFEAQE+A + ENVPPVI TPHHYL+S+Y
Sbjct: 1   MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY 60

Query: 61  RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG 120
           R K+FFV+VIQTEVPPLFVIEFLHRV DTFQDYFG CSE  IKDNVV+VYE+LEEMLDNG
Sbjct: 61  RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG 120

Query: 121 FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAY 180
           FPLATESNILKELIKPPTILR+VVN+ITGS+NVGD LPTGQLS +PWRR GVKYTNNEAY
Sbjct: 121 FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY 180

Query: 181 FDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFK 240
           FDV+EEIDAIIDKSGST+ AEIQGVIDAC+KL+GMPDL+LSFMNPRLLDDVSFHPC+RFK
Sbjct: 181 FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFK 240

Query: 241 RWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQN 300
           RWESER+LSFIPPDGNFRL+SY VS+QNLVAIPVYVKH+ISF+++SS GRF+IT+GPKQ 
Sbjct: 241 RWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQT 300

Query: 301 MGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKITPQKLPSLKGLVNL 360
           MGKTIEG+TVT  MPK VLNM+LTP+QG++TFDPVTK+L+WDVGKI PQKLPSLKG ++L
Sbjct: 301 MGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSL 360

Query: 361 QSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKYVTKAGKFQVRT 418
           Q+GA KP+ENP++N+QFKIQQLAISGLKVNRLDMYGEKYKPFKG+KY+TKAGKFQVRT
Sbjct: 361 QAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT 418


>gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo
           sapiens]
          Length = 423

 Score =  204 bits (518), Expect = 2e-52
 Identities = 128/434 (29%), Positives = 225/434 (51%), Gaps = 35/434 (8%)

Query: 4   SLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIYRDK 63
           ++F+++  G   + +++K  V+ S  ++F     +  +   + P++S    + + I    
Sbjct: 5   AVFILDVKGKPLISRNYKGDVAMSKIEHFMPLLVQREEEGALAPLLSHGQVHFLWIKHSN 64

Query: 64  LFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNGFPL 123
           L+ V+          V  FL++  + F +YF E  E +I+DN VIVYELL+E++D GFP 
Sbjct: 65  LYLVATTSKNANASLVYSFLYKTIEVFCEYFKELEEESIRDNFVIVYELLDELMDFGFPQ 124

Query: 124 ATESNILKELIKPPTILRSVVNSI-TGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAYFD 182
            T+S IL+E I   +      N + TG S V  T+       + WR  G+KY  NE + D
Sbjct: 125 TTDSKILQEYITQQS------NKLETGKSRVPPTVTNA----VSWRSEGIKYKKNEVFID 174

Query: 183 VVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRL--------------L 228
           V+E ++ +++ +GS + +EI G I   + LSGMP+L L  +N R+              L
Sbjct: 175 VIESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLG-LNDRVLFELTGRSKNKSVEL 233

Query: 229 DDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSC 288
           +DV FH C+R  R++++R +SFIPPDG+F L+SYR+S+Q  V   ++++  I   E  S 
Sbjct: 234 EDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQ--VKPLIWIESVI---EKFSH 288

Query: 289 GRFDITIGPKQNMGK--TIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKI 346
            R +I +  K    K     G+ ++V +P    +     + GS  + P   V+ W +   
Sbjct: 289 SRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPERNVVIWSIKSF 348

Query: 347 TPQKLPSLKGLVNLQS-GAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEK-YKPFKG 404
              K   ++    L S    + E  P + ++F+I    +SG++V  + +  +  Y+    
Sbjct: 349 PGGKEYLMRAHFGLPSVEKEEVEGRPPIGVKFEIPYFTVSGIQVRYMKIIEKSGYQALPW 408

Query: 405 VKYVTKAGKFQVRT 418
           V+Y+T++G +Q+RT
Sbjct: 409 VRYITQSGDYQLRT 422


>gi|14210504 adaptor-related protein complex 1, mu 1 subunit isoform
           2 [Homo sapiens]
          Length = 423

 Score =  186 bits (471), Expect = 4e-47
 Identities = 118/433 (27%), Positives = 213/433 (49%), Gaps = 33/433 (7%)

Query: 4   SLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIYRDK 63
           ++++++  G + + ++++  V  S  ++F     +  +   + P+++      + I  + 
Sbjct: 5   AVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNN 64

Query: 64  LFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNGFPL 123
           L+ V+  +       V  FL++V   F +YF E  E +I+DN VI+YELL+E++D G+P 
Sbjct: 65  LYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQ 124

Query: 124 ATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSN-IPWRRAGVKYTNNEAYFD 182
            T+S IL+E I                   G   P   ++N + WR  G+KY  NE + D
Sbjct: 125 TTDSKILQEYI----------TQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLD 174

Query: 183 VVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRL-------------LD 229
           V+E ++ ++  +G+ + +EI G I   + LSGMP+L L   +  L             L+
Sbjct: 175 VIESVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKSKSVELE 234

Query: 230 DVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCG 289
           DV FH C+R  R+E++R +SFIPPDG F L+SYR+++   V   ++++  I   E  S  
Sbjct: 235 DVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTH--VKPLIWIESVI---EKHSHS 289

Query: 290 RFDITIGPKQNMGK--TIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKIT 347
           R +  I  K    +  T   + + + +P    +     T GS  + P    + W +    
Sbjct: 290 RIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSFP 349

Query: 348 PQKLPSLKGLVNLQS-GAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEK-YKPFKGV 405
             K   ++    L S  A   E  P ++++F+I     SG++V  L +  +  Y+    V
Sbjct: 350 GGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWV 409

Query: 406 KYVTKAGKFQVRT 418
           +Y+T+ G +Q+RT
Sbjct: 410 RYITQNGDYQLRT 422


>gi|194473724 adaptor-related protein complex 1, mu 1 subunit
           isoform 1 [Homo sapiens]
          Length = 435

 Score =  177 bits (448), Expect = 2e-44
 Identities = 118/445 (26%), Positives = 213/445 (47%), Gaps = 45/445 (10%)

Query: 4   SLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIYRDK 63
           ++++++  G + + ++++  V  S  ++F     +  +   + P+++      + I  + 
Sbjct: 5   AVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNN 64

Query: 64  LFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNGFPL 123
           L+ V+  +       V  FL++V   F +YF E  E +I+DN VI+YELL+E++D G+P 
Sbjct: 65  LYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQ 124

Query: 124 ATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSN-IPWRRAGVKYTNNEAYFD 182
            T+S IL+E I                   G   P   ++N + WR  G+KY  NE + D
Sbjct: 125 TTDSKILQEYI----------TQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLD 174

Query: 183 VVEEIDAI------------IDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRL--- 227
           V+E ++ +            +  +G+ + +EI G I   + LSGMP+L L   +  L   
Sbjct: 175 VIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDN 234

Query: 228 ----------LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVK 277
                     L+DV FH C+R  R+E++R +SFIPPDG F L+SYR+++   V   ++++
Sbjct: 235 TGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTH--VKPLIWIE 292

Query: 278 HSISFKENSSCGRFDITIGPKQNMGK--TIEGITVTVHMPKVVLNMNLTPTQGSYTFDPV 335
             I   E  S  R +  I  K    +  T   + + + +P    +     T GS  + P 
Sbjct: 293 SVI---EKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPE 349

Query: 336 TKVLTWDVGKITPQKLPSLKGLVNLQS-GAPKPEENPSLNIQFKIQQLAISGLKVNRLDM 394
              + W +      K   ++    L S  A   E  P ++++F+I     SG++V  L +
Sbjct: 350 NSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKI 409

Query: 395 YGEK-YKPFKGVKYVTKAGKFQVRT 418
             +  Y+    V+Y+T+ G +Q+RT
Sbjct: 410 IEKSGYQALPWVRYITQNGDYQLRT 434


>gi|14917109 adaptor-related protein complex 2, mu 1 subunit isoform
           a [Homo sapiens]
          Length = 435

 Score =  162 bits (410), Expect = 5e-40
 Identities = 116/447 (25%), Positives = 206/447 (46%), Gaps = 43/447 (9%)

Query: 1   MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY 60
           MI  LF+ N  G++ + + ++  + ++  D F       A  +   PV +        + 
Sbjct: 1   MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAF-RVNVIHARQQVRSPVTNIARTSFFHVK 59

Query: 61  RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG 120
           R  ++  +V +  V    V EFL+++ D    YFG+ SE  IK+N V++YELL+E+LD G
Sbjct: 60  RSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFG 119

Query: 121 FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAY 180
           +P  +E+  LK  I    I +S   +    S +   + TGQ   I WRR G+KY  NE +
Sbjct: 120 YPQNSETGALKTFITQQGI-KSQHQTKEEQSQITSQV-TGQ---IGWRREGIKYRRNELF 174

Query: 181 FDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRL------------- 227
            DV+E ++ ++   G  + A + G +     LSGMP+     MN ++             
Sbjct: 175 LDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFG-MNDKIVIEKQGKGTADET 233

Query: 228 ---------LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKH 278
                    +DD +FH C+R  +++SER +SFIPPDG F L+ YR +   ++   V    
Sbjct: 234 SKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRV---- 289

Query: 279 SISFKENSSCGRFDITIGPKQNMGKTI--EGITVTVHMPKVVLNMNLTPTQGSYTFDPVT 336
            I         + ++ +  K N   ++  + I V +  P     + +   +G   +    
Sbjct: 290 -IPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASE 348

Query: 337 KVLTWDVGKITPQKLPSLKGLVN-LQSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMY 395
             + W + ++   K   +   +  L +   K    P +++ F++   A SGLKV  L ++
Sbjct: 349 NAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEV-PFAPSGLKVRYLKVF 407

Query: 396 GEK-----YKPFKGVKYVTKAGKFQVR 417
             K     +   K V+Y+ ++G ++ R
Sbjct: 408 EPKLNYSDHDVIKWVRYIGRSGIYETR 434


>gi|68799814 adaptor-related protein complex 2, mu 1 subunit isoform
           b [Homo sapiens]
          Length = 433

 Score =  161 bits (407), Expect = 1e-39
 Identities = 113/448 (25%), Positives = 203/448 (45%), Gaps = 47/448 (10%)

Query: 1   MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY 60
           MI  LF+ N  G++ + + ++  + ++  D F       A  +   PV +        + 
Sbjct: 1   MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAF-RVNVIHARQQVRSPVTNIARTSFFHVK 59

Query: 61  RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG 120
           R  ++  +V +  V    V EFL+++ D    YFG+ SE  IK+N V++YELL+E+LD G
Sbjct: 60  RSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFG 119

Query: 121 FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLS-NIPWRRAGVKYTNNEA 179
           +P  +E+  LK  I            I   +    +  T Q++  I WRR G+KY  NE 
Sbjct: 120 YPQNSETGALKTFI--------TQQGIKSQTKEEQSQITSQVTGQIGWRREGIKYRRNEL 171

Query: 180 YFDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRL------------ 227
           + DV+E ++ ++   G  + A + G +     LSGMP+     MN ++            
Sbjct: 172 FLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFG-MNDKIVIEKQGKGTADE 230

Query: 228 ----------LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVK 277
                     +DD +FH C+R  +++SER +SFIPPDG F L+ YR +   ++   V   
Sbjct: 231 TSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRV--- 287

Query: 278 HSISFKENSSCGRFDITIGPKQNMGKTI--EGITVTVHMPKVVLNMNLTPTQGSYTFDPV 335
             I         + ++ +  K N   ++  + I V +  P     + +   +G   +   
Sbjct: 288 --IPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKAS 345

Query: 336 TKVLTWDVGKITPQKLPSLKGLVN-LQSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDM 394
              + W + ++   K   +   +  L +   K    P +++ F++   A SGLKV  L +
Sbjct: 346 ENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEV-PFAPSGLKVRYLKV 404

Query: 395 YGEK-----YKPFKGVKYVTKAGKFQVR 417
           +  K     +   K V+Y+ ++G ++ R
Sbjct: 405 FEPKLNYSDHDVIKWVRYIGRSGIYETR 432


>gi|14917111 adaptor-related protein complex 4, mu 1 subunit [Homo
           sapiens]
          Length = 453

 Score =  111 bits (277), Expect = 1e-24
 Identities = 104/460 (22%), Positives = 190/460 (41%), Gaps = 51/460 (11%)

Query: 1   MIHSLFLINCSGDIFLEKHWKSVVS-QSVCDYFFEAQEKAADVENVPPVISTPH-HYLIS 58
           MI   F+++  GD  + K ++     + V + F+         E+  PV+   H  + I 
Sbjct: 1   MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDES--PVVMHHHGRHFIH 58

Query: 59  IYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLD 118
           I    L+ V      V P  ++E L R+A    DY G   E  I  NV +VYELL+E+LD
Sbjct: 59  IRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLD 118

Query: 119 NGFPLATESNILKELIKPPTILR--------SVVNSITGSSNVGDTLPTGQLSNIPWRRA 170
            G+   T + +L+  I+   ++         S V      +      P+   S       
Sbjct: 119 YGYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSR 178

Query: 171 GVKYTNNEAYFDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSF-------- 222
             +   NE + DVVE +  +I  +GS +  ++QG I     L    ++ +          
Sbjct: 179 SDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGK 238

Query: 223 -----MNPRL-LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYV 276
                  P + +D+VSFH  +    +ES R+L   PP G   ++ Y++S      +P  +
Sbjct: 239 SELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRL 298

Query: 277 KHSISFKENSSCGRFDITIGPKQNMGKTIEGITVTVH--MPKVVLNMNLTPTQGSYTFDP 334
             S+ +   S  GR  + +  + ++    + + V +H  +P+ V++++   +      + 
Sbjct: 299 FPSVQWDRGS--GRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAEL 356

Query: 335 VTKVLTWDVGKITPQKLPSLKGLVNLQSGAPKPEENPS--------------LNIQFKIQ 380
               L WD+ ++  Q    L GL   Q   P P   PS               ++ F++ 
Sbjct: 357 AEGALRWDLPRV--QGGSQLSGL--FQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELP 412

Query: 381 QLAISGLKVNRLDMYGE---KYKPFKGVKYVTKAGKFQVR 417
           +   SGL+V  L +         P K V++++ +  + +R
Sbjct: 413 RHTCSGLQVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIR 452


>gi|88703051 adaptor-related protein complex 1, sigma 3 subunit
           [Homo sapiens]
          Length = 154

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 35/154 (22%), Positives = 62/154 (40%), Gaps = 19/154 (12%)

Query: 1   MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHY----- 55
           MIH + L +  G + L+K + ++  +         + K    E V  ++S  H       
Sbjct: 1   MIHFILLFSRQGKLRLQKWYITLPDK---------ERKKITREIVQIILSRGHRTSSFVD 51

Query: 56  ---LISIYRD--KLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVY 110
              L  +Y+    L+F   I+ +   L  +E +HR  +    YFG   E  I  N    Y
Sbjct: 52  WKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAY 111

Query: 111 ELLEEMLDNGFPLATESNILKELIKPPTILRSVV 144
            +L+E +  G    T   I  + I+   +L+  +
Sbjct: 112 FILDEFIIGGEIQETSKKIAVKAIEDSDMLQETM 145


>gi|189409104 adaptor-related protein complex 4, sigma 1 subunit
           isoform 2 [Homo sapiens]
          Length = 144

 Score = 36.6 bits (83), Expect = 0.043
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 59  IYRD--KLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEM 116
           IYR    LF V  +      + + EF+H   +   +YF   SE  I  N+  V+ +L+EM
Sbjct: 58  IYRQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIILDEM 117

Query: 117 LDNGFPLAT-ESNILKELI 134
           + NG  + T  + IL  L+
Sbjct: 118 VLNGCIVETNRARILAPLL 136


>gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [Homo
           sapiens]
          Length = 157

 Score = 36.2 bits (82), Expect = 0.057
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 1/71 (1%)

Query: 64  LFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNGFPL 123
           L+F   I+ +   L  +E +HR  +    YFG   E  I  N    Y +L+E L  G   
Sbjct: 64  LYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQ 123

Query: 124 AT-ESNILKEL 133
            T + N+LK +
Sbjct: 124 ETSKKNVLKAI 134


>gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [Homo
           sapiens]
          Length = 158

 Score = 35.0 bits (79), Expect = 0.13
 Identities = 21/78 (26%), Positives = 34/78 (43%)

Query: 64  LFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNGFPL 123
           L+F   I+ +   L  +E +HR  +    YFG   E  I  N    Y +L+E L  G   
Sbjct: 65  LYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQ 124

Query: 124 ATESNILKELIKPPTILR 141
            T    + + I+   +L+
Sbjct: 125 DTSKKSVLKAIEQADLLQ 142


>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
          Length = 1073

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 14/50 (28%), Positives = 28/50 (56%)

Query: 101  AIKDNVVIVYELLEEMLDNGFPLATESNILKELIKPPTILRSVVNSITGS 150
            A+++ V ++ E ++E+++    L  E+N+LK L  P  + +      TGS
Sbjct: 998  AVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGS 1047


>gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens]
          Length = 144

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 14/50 (28%), Positives = 28/50 (56%)

Query: 101 AIKDNVVIVYELLEEMLDNGFPLATESNILKELIKPPTILRSVVNSITGS 150
           A+++ V ++ E ++E+++    L  E+N+LK L  P  + +      TGS
Sbjct: 69  AVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGS 118


>gi|26787993 stonin 1 [Homo sapiens]
          Length = 735

 Score = 30.4 bits (67), Expect = 3.1
 Identities = 11/35 (31%), Positives = 20/35 (57%), Gaps = 1/35 (2%)

Query: 230 DVSFHPCIRFKRWESERVLSFIPPDG-NFRLISYR 263
           D  FH C+  + +E  R++ F+P D   F L+ ++
Sbjct: 484 DYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFK 518


>gi|29553944 STON1-GTF2A1L protein [Homo sapiens]
          Length = 1182

 Score = 30.4 bits (67), Expect = 3.1
 Identities = 11/35 (31%), Positives = 20/35 (57%), Gaps = 1/35 (2%)

Query: 230 DVSFHPCIRFKRWESERVLSFIPPDG-NFRLISYR 263
           D  FH C+  + +E  R++ F+P D   F L+ ++
Sbjct: 484 DYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFK 518


>gi|4757768 Rho GDP dissociation inhibitor (GDI) alpha [Homo
           sapiens]
          Length = 204

 Score = 29.6 bits (65), Expect = 5.3
 Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 5/102 (4%)

Query: 243 ESERVLSFIPPDG-NFRL-ISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQN 300
           ES +  SF+  +G  +R+ IS+RV+ + +V+   Y++H+  +++     + D  +G    
Sbjct: 95  ESFKKQSFVLKEGVEYRIKISFRVNRE-IVSGMKYIQHT--YRKGVKIDKTDYMVGSYGP 151

Query: 301 MGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWD 342
             +  E +T     PK +L       +  +T D  T  L+W+
Sbjct: 152 RAEEYEFLTPVEEAPKGMLARGSYSIKSRFTDDDKTDHLSWE 193


>gi|70906430 adaptor-related protein complex 2, sigma 1 subunit
           isoform AP17 [Homo sapiens]
          Length = 142

 Score = 29.6 bits (65), Expect = 5.3
 Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 12/114 (10%)

Query: 33  FEAQEKAADVENVPPVIST---PHHYLIS------IYRDK--LFFVSVIQTEVPPLFVIE 81
           F+  EK   +E V  V++     H   +       IYR    L+F   +      L  +E
Sbjct: 23  FDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLE 82

Query: 82  FLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEM-LDNGFPLATESNILKELI 134
            +H   +   +YF    E  +  N   VY +++EM L       +++ +LK+L+
Sbjct: 83  AIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLL 136


>gi|4506585 replication protein A2, 32kDa [Homo sapiens]
          Length = 270

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 16/135 (11%)

Query: 265 SSQNLVAIP-VYVK---HSISFKENSSCGRFDITIGPKQNMGKTIEGITVTVHMPKVVLN 320
           SS+N V  P  YVK   H  SF+   S   F I   P ++M +    I   ++   V+  
Sbjct: 114 SSENTVVPPETYVKVAGHLRSFQNKKSLVAFKIM--PLEDMNEFTTHILEVINAHMVLSK 171

Query: 321 MNLTPTQGSYTFDPVTKVLTWDVGKITPQKLPSLKGL-------VNLQSGAPKPEENPSL 373
            N  P+ G     P++     + G           GL       +NL    P+PE     
Sbjct: 172 ANSQPSAGRA---PISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQ 228

Query: 374 NIQFKIQQLAISGLK 388
           +++ +++ +++S +K
Sbjct: 229 DLKNQLKHMSVSSIK 243


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,620,702
Number of Sequences: 37866
Number of extensions: 672721
Number of successful extensions: 1446
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1405
Number of HSP's gapped (non-prelim): 21
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.