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Search of human proteins with 46361983
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46361983 hydrocephalus inducing isoform b [Homo sapiens]
(1017 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46361983 hydrocephalus inducing isoform b [Homo sapiens] 2060 0.0
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens] 2055 0.0
gi|90669228 deleted in lung and esophageal cancer 1 isoform DLEC... 118 2e-26
gi|90669194 deleted in lung and esophageal cancer 1 isoform DLEC... 118 2e-26
gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa... 61 6e-09
gi|90963001 hypothetical protein LOC170063 [Homo sapiens] 42 0.003
gi|50811889 centrosomal protein 192kDa [Homo sapiens] 35 0.27
gi|122937416 hypothetical protein LOC85452 [Homo sapiens] 35 0.47
gi|166064027 cyclin-dependent kinase-like 3 isoform 1 [Homo sapi... 33 1.4
gi|166064025 cyclin-dependent kinase-like 3 isoform 2 [Homo sapi... 33 1.4
gi|157694511 nucleolar complex associated 2 homolog [Homo sapiens] 33 1.8
gi|33469935 EGF-like, fibronectin type III and laminin G domains... 32 3.0
gi|33469931 EGF-like, fibronectin type III and laminin G domains... 32 3.0
gi|33469929 EGF-like, fibronectin type III and laminin G domains... 32 3.0
gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens] 32 4.0
gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens] 32 4.0
gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens] 32 4.0
gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s... 32 4.0
gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens] 32 4.0
gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens] 32 4.0
gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo ... 32 4.0
>gi|46361983 hydrocephalus inducing isoform b [Homo sapiens]
Length = 1017
Score = 2060 bits (5336), Expect = 0.0
Identities = 1017/1017 (100%), Positives = 1017/1017 (100%)
Query: 1 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE 60
MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE
Sbjct: 1 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE 60
Query: 61 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL 120
QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL
Sbjct: 61 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL 120
Query: 121 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC 180
ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC
Sbjct: 121 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC 180
Query: 181 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP 240
VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP
Sbjct: 181 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP 240
Query: 241 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD 300
FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD
Sbjct: 241 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD 300
Query: 301 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE 360
KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE
Sbjct: 301 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE 360
Query: 361 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE 420
TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE
Sbjct: 361 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE 420
Query: 421 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC 480
ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC
Sbjct: 421 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC 480
Query: 481 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE 540
YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE
Sbjct: 481 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE 540
Query: 541 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK 600
FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK
Sbjct: 541 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK 600
Query: 601 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT 660
LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT
Sbjct: 601 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT 660
Query: 661 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL 720
LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL
Sbjct: 661 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL 720
Query: 721 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV 780
QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV
Sbjct: 721 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV 780
Query: 781 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ 840
YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ
Sbjct: 781 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ 840
Query: 841 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS 900
AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS
Sbjct: 841 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS 900
Query: 901 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG 960
GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG
Sbjct: 901 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG 960
Query: 961 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRVRG 1017
RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRVRG
Sbjct: 961 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRVRG 1017
>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
Length = 5120
Score = 2055 bits (5324), Expect = 0.0
Identities = 1014/1015 (99%), Positives = 1015/1015 (100%)
Query: 1 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE 60
MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE
Sbjct: 1 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE 60
Query: 61 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL 120
QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL
Sbjct: 61 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL 120
Query: 121 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC 180
ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC
Sbjct: 121 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC 180
Query: 181 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP 240
VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP
Sbjct: 181 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP 240
Query: 241 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD 300
FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD
Sbjct: 241 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD 300
Query: 301 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE 360
KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE
Sbjct: 301 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE 360
Query: 361 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE 420
TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE
Sbjct: 361 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE 420
Query: 421 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC 480
ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC
Sbjct: 421 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC 480
Query: 481 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE 540
YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE
Sbjct: 481 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE 540
Query: 541 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK 600
FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK
Sbjct: 541 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK 600
Query: 601 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT 660
LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT
Sbjct: 601 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT 660
Query: 661 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL 720
LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL
Sbjct: 661 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL 720
Query: 721 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV 780
QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV
Sbjct: 721 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV 780
Query: 781 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ 840
YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ
Sbjct: 781 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ 840
Query: 841 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS 900
AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS
Sbjct: 841 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS 900
Query: 901 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG 960
GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG
Sbjct: 901 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG 960
Query: 961 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRV 1015
RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPR+
Sbjct: 961 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRI 1015
Score = 50.4 bits (119), Expect = 8e-06
Identities = 22/69 (31%), Positives = 39/69 (56%)
Query: 403 VFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIH 462
+F ++P+ G + P + + V F P E K Y QT+ I +L L +G+G+ P++
Sbjct: 1765 IFEIQPISGVLDPGEKSNVQVKFMPKEEKFYSQTLVFQIAQSAQKLTLLARGQGLEPRLE 1824
Query: 463 FNFELLDIG 471
F+ +LD+G
Sbjct: 1825 FSPSVLDLG 1833
Score = 50.1 bits (118), Expect = 1e-05
Identities = 88/425 (20%), Positives = 161/425 (37%), Gaps = 71/425 (16%)
Query: 508 FVFSPKEGIIEPSGVQAIQISFSSTILGNFEEEFLVNVNGSPE----PVKLTIRGCVIGP 563
F P GI+ +Q ++ FS +G+FE + P PV L +G P
Sbjct: 3889 FSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPV-LVAKGRSTLP 3947
Query: 564 TFHFNVPALHFGDVSFGFPHTLICSLNNTS---LIPMTYKLRIPGDGLGHKSI------- 613
HF++ D + H L +S L P T + G+G K++
Sbjct: 3948 ICHFDLK-----DSDYISGHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILN 4002
Query: 614 ------SYCEQHVDYKRPSWTKEEISSMK-PKEFTISPDCGTIRPQGFAAI--RVTLCSN 664
S+C W EEI S++ P FT + G I P+ A I + T
Sbjct: 4003 PTNSTYSFC----------WISEEIESLQNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHL 4052
Query: 665 TVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTLQLAN 724
+ + ++ I + L+ + P + L + ++F + +T+Q+ N
Sbjct: 4053 GITESSWTFLIPEHNI---TVPFLLVGKTTEPLISLNKSHLNFSSLLIGREARETVQIIN 4109
Query: 725 QDDLPGF---YEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTVY 781
+++ GF ++ + E L P G I P S I + + G+ +
Sbjct: 4110 KEE-QGFDFSFQDNSRYSEGFSNSLLVCPM-EGWIPPLSRFPIDIFFTPKQEGDVNFNLI 4167
Query: 782 ISIFGSQDPPLVCHLKSAG------------EGPVIYVHPNQVDFGNIYVLKDSSRI--- 826
++ + P+ ++K+ G G + + PNQ + N Y ++ + +
Sbjct: 4168 CNV-EKKVHPVTLNVKAEGYTMNVEIKCKDRTGSITLLTPNQTNIINFYEVELNECVQCE 4226
Query: 827 LNLCNQSFIPAFFQAHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTF---KDCV 883
N N FQA + K+L + + D + + +++ TL+F K CV
Sbjct: 4227 FNFINTGKFTFSFQAQLCGSKTLL-----QYLEFSPIDSTVDVGQSVHATLSFQPLKKCV 4281
Query: 884 ILDIE 888
+ D+E
Sbjct: 4282 LTDLE 4286
Score = 47.0 bits (110), Expect = 9e-05
Identities = 129/739 (17%), Positives = 250/739 (33%), Gaps = 141/739 (19%)
Query: 239 RPFSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLI----------------------- 275
+PFS+EP+ G + VG+ + +V+F P +GD L
Sbjct: 3887 QPFSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTL 3946
Query: 276 -VC-YDTGEKVFVSLYGAAIDMNIR------LDKNSLTIEKTYISLA--NQRTITIHNRS 325
+C +D + ++S G + +R LD N+ IE T + + N RT TI N +
Sbjct: 3947 PICHFDLKDSDYIS--GHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPT 4004
Query: 326 NIIAHFLWKVFATQQEEDREKYRACDD---LIKEEKDETDEFF----------------- 365
N F W + ++ + + + E+K E F
Sbjct: 4005 NSTYSFCWISEEIESLQNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFLIP 4064
Query: 366 EECITDPLL-------------REHLSVLSRTFANQRR----LVQGDSKLF--------- 399
E IT P L + HL+ S + R ++ + + F
Sbjct: 4065 EHNITVPFLLVGKTTEPLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSFQDNSR 4124
Query: 400 ----FNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGE 455
F+N V P+EG + P S I ++F P + + C++ + + L +K E
Sbjct: 4125 YSEGFSNSLLVCPMEGWIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAE 4184
Query: 456 GMGPKIHFNFE---------------LLDIGKVFTGSAHCYEAILYNKGSIDALFN-MTP 499
G + + +++ +V E N G F
Sbjct: 4185 GYTMNVEIKCKDRTGSITLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQAQLC 4244
Query: 500 PTSALGACFVFSPKEGIIEPSGVQAIQISF---SSTILGNFEEEFLVNVNGSPEPVKLTI 556
+ L FSP + ++ +SF +L + E ++ ++ P I
Sbjct: 4245 GSKTLLQYLEFSPIDSTVDVGQSVHATLSFQPLKKCVLTDL--ELIIKISHGP-TFMCNI 4301
Query: 557 RGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYKLRIPGDGLGHKSISYC 616
GC + P HF+ + +FG C + + P L I
Sbjct: 4302 SGCAVSPAIHFSFTSYNFG----------TCFIYQAGMPPYKQTLVITNK-------EET 4344
Query: 617 EQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVTLCSNTVQKYELALVVD 676
+D + T E++S ++P I +T Y+ + +
Sbjct: 4345 PMSIDCLYTNTTHLEVNSR----------VDVVKPGNTLEIPITFYPRESINYQELIPFE 4394
Query: 677 VEGIGEEVLALL-ITARCVVPALHLVNTEVDFGHCFLKYPYEKTLQLANQD--DLPGFYE 733
+ G+ ++ + + + + L N V G ++T+ + N L
Sbjct: 4395 INGLSQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQS 4454
Query: 734 VQPQVCE-EVPTVLFSSPTPSGVISPSSTIHIPLVLETQV-TGEHRSTVYISIFGSQDPP 791
+ + E + P VL +P + + P + ++ + V++ G P
Sbjct: 4455 ILFTIPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPL 4514
Query: 792 LVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQAHMAHKKSLWT 851
+ L + I + + FG + ++R + + N + A F+ + + ++
Sbjct: 4515 FL--LSGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARFKWDIKKFEPHFS 4572
Query: 852 IEPNEGMVPPETDVQLALT 870
I P EG + +V +T
Sbjct: 4573 ISPEEGYITSGMEVSFEVT 4591
Score = 40.4 bits (93), Expect = 0.009
Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 791 PLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ-AHMAHKKSL 849
P + L G P + + P Q+ F + + + SR++ L N + +P ++ + H
Sbjct: 2919 PAIFQLSCQGIRPELELEPRQLHFDRLLLHRQESRVVLLRNVTLLPVAWRITSLEHLGDD 2978
Query: 850 WTIEPNEGMVPPETDVQLALTANLNDTLTFKDCV---ILDIEN 889
+T+ +G +PPE + L L + K + +LD EN
Sbjct: 2979 FTVSLMQGTIPPEAEYGLHLYFQPTKPVNIKKAIRLEVLDAEN 3021
Score = 39.3 bits (90), Expect = 0.019
Identities = 20/94 (21%), Positives = 42/94 (44%)
Query: 508 FVFSPKEGIIEPSGVQAIQISFSSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHF 567
+ P +++P+ Q + + T +G FE+ + +N +PEP + I P
Sbjct: 2876 YFLEPNTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELEL 2935
Query: 568 NVPALHFGDVSFGFPHTLICSLNNTSLIPMTYKL 601
LHF + + + L N +L+P+ +++
Sbjct: 2936 EPRQLHFDRLLLHRQESRVVLLRNVTLLPVAWRI 2969
Score = 33.9 bits (76), Expect = 0.80
Identities = 60/287 (20%), Positives = 112/287 (39%), Gaps = 32/287 (11%)
Query: 73 QIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEV-------PLILRNN 125
++I + G T SG + A+ F S N+ C +Y+ L++ N
Sbjct: 4286 ELIIKISHGPTFMCNISGCAVSPAIHFSFTS----YNFGTCFIYQAGMPPYKQTLVITNK 4341
Query: 126 DKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC-VTER 184
++ P + + ++ + +V S D+ V PG I F P E+ +Y + +
Sbjct: 4342 EETPMSIDCLYTNTTHLEVNSRVDV---VKPGNTLEIPITFYPRESINYQELIPFEINGL 4398
Query: 185 EKFIVPIKARGARAILDFPDKLNF-----STCPVKYSTQKILLVRN-----IGNKNAVFH 234
+ V IK +G + + D N + P + + + ++ N N++ +F
Sbjct: 4399 SQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQSILFT 4458
Query: 235 IKTCRP---FSIEPAIG-TLNVGESMQLEVEFEPQS-VGDHSGRLIV-CYDTGEKVFVSL 288
I + ++ P TL E +LEV F P+ V S + + C +F+ L
Sbjct: 4459 IPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPLFL-L 4517
Query: 289 YGAAIDMNIRLDKNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKV 335
G + I LD+ + R I + N ++ A F W +
Sbjct: 4518 SGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARFKWDI 4564
Score = 32.7 bits (73), Expect = 1.8
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 10/92 (10%)
Query: 212 PVKYST----QKILLVR--NIGNKNAVFHIKT-CRPFSIEPAIGTLNVGES---MQLEVE 261
PV + T +I+LV+ N + ++ +T C F E I G+ +EV
Sbjct: 4930 PVHFQTVLGSSQIILVKFINYTRQRTEYYCRTDCTDFHAEKLINAAPGGQGGTEASVEVL 4989
Query: 262 FEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAI 293
FEP +G+ G LI+ G + + L+G A+
Sbjct: 4990 FEPSHLGETKGILILSSLAGGEYIIPLFGMAL 5021
Score = 32.3 bits (72), Expect = 2.3
Identities = 38/175 (21%), Positives = 70/175 (40%), Gaps = 11/175 (6%)
Query: 403 VFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIH 462
VF + PL G + P+SS +I+ F + Q C++ E I +G ++
Sbjct: 1328 VFDILPLFGVLQPHSSHQISFTFYGHANIIAQAKALCEV---EEGPTYEITLKGEASLVN 1384
Query: 463 FNFELLDI--GKVFTGSAHCYEAILYNKGSIDALF-----NMTPPTSALGACFVFSPKEG 515
++F+ DI G E L N G + F + + P + L + P G
Sbjct: 1385 YSFDTKDIHYGLQLFDHVTEREITLTNMGKVGFEFKVLTDHQSSPDNLLPGVPLILPVSG 1444
Query: 516 IIEPSGVQAIQISFSSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHFNVP 570
I Q +++ + + F+ F + + +P +T+ G I P ++P
Sbjct: 1445 FISSHQEQVLKVYYLPGVPEVFKRSFQIQI-AHLDPENITLSGEGIFPQICLDLP 1498
Score = 32.0 bits (71), Expect = 3.0
Identities = 23/138 (16%), Positives = 54/138 (39%), Gaps = 5/138 (3%)
Query: 787 SQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDS----SRILNLCNQSFIPAFFQAH 842
S P +C++ P I+ +FG ++ + + L + N+ P
Sbjct: 4292 SHGPTFMCNISGCAVSPAIHFSFTSYNFGTCFIYQAGMPPYKQTLVITNKEETPMSIDCL 4351
Query: 843 MAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQASGT 902
+ L + +V P +++ +T +++ +++ + +I S + ++ GT
Sbjct: 4352 YTNTTHL-EVNSRVDVVKPGNTLEIPITFYPRESINYQELIPFEINGLSQQTVEIKGKGT 4410
Query: 903 GSTIVSDKPFAPELNLGA 920
I+ P + LGA
Sbjct: 4411 KMKILVLDPANRIVKLGA 4428
Score = 31.2 bits (69), Expect = 5.2
Identities = 27/144 (18%), Positives = 54/144 (37%), Gaps = 1/144 (0%)
Query: 402 NVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKI 461
N + +EP + PN + V+ P +++ +I C I ++ +G+ P++
Sbjct: 2874 NTYFLEPNTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPEL 2933
Query: 462 HFNFELLDIGKVFTGSAHCYEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSG 521
L ++ +L N + + +T LG F S +G I P
Sbjct: 2934 ELEPRQLHFDRLLLHRQESRVVLLRNVTLLPVAWRIT-SLEHLGDDFTVSLMQGTIPPEA 2992
Query: 522 VQAIQISFSSTILGNFEEEFLVNV 545
+ + F T N ++ + V
Sbjct: 2993 EYGLHLYFQPTKPVNIKKAIRLEV 3016
>gi|90669228 deleted in lung and esophageal cancer 1 isoform DLEC1-S3
[Homo sapiens]
Length = 1778
Score = 118 bits (296), Expect = 2e-26
Identities = 172/809 (21%), Positives = 307/809 (37%), Gaps = 111/809 (13%)
Query: 94 DQALFQPFPSEIIFQNYTPCEVYEVPLILRNNDKIPRLVKVVEESSPYFKV---ISPKDI 150
D +F P F +Y VYE+ + L+N R ++V+ S+PYF + + P
Sbjct: 368 DTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGK- 426
Query: 151 GHKVAPGVPSIFRILFTPEENKDYAHTLTCVTE-REKFIVPIKARGARAILDFPDKLNFS 209
G VAPG+ + + F P+ D+ + T+ ++P++AR +L L+
Sbjct: 427 GGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCG 486
Query: 210 TCPVKYSTQKILLVRNIGNKNAVFHI--KTC-----------------RPFSIEPAIGTL 250
C + + +N+G F I KT PF I P++ L
Sbjct: 487 YCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFEL 546
Query: 251 NVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLTIEKTY 310
G ++ +EV F P+S+G I+ D + L I I LD ++ EK+
Sbjct: 547 APGHAILVEVLFSPKSLGKAEQTFIIMCDNCQ--IKELVTIGIGQLIALDLIYISGEKSQ 604
Query: 311 ISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDETDEFFEECIT 370
+T HF+ + E + + A LI + F I
Sbjct: 605 PDPGELTDLTAQ-------HFI------RFEPENLRSTARKQLIIRNATHVELAFYWQIM 651
Query: 371 DPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEA 430
P L+ + TF+ D + F++ P +G + P++ E + F+P E
Sbjct: 652 KPNLQPLMP--GETFSMDSIKCYPDKE----TAFSIMPRKGVLSPHTDHEFILSFSPHEL 705
Query: 431 KLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHCYEAIL----- 485
+ + + ++ E+ P+ + E +G + +++ + GS ++ +L
Sbjct: 706 RDFHSVL--QMVLEEVPEPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYAL 763
Query: 486 ------YNKGSIDALFNMTPPTSA--------LGACFVF--SPKEGIIEPSGVQAIQISF 529
Y ++ F M + + + C + P G+IEPS V +++F
Sbjct: 764 IIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNF 823
Query: 530 SSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSL 589
+ + G ++ L + SP PV L I GP NV AL FG + G T +
Sbjct: 824 TGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQI 883
Query: 590 NNTSLIPMTYKLRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTI 649
N S +P T++++ + P +E + P F I P G +
Sbjct: 884 RNVSQLPATWRMK--------------------ESPVSLQERPEDVSP--FDIEPSSGQL 921
Query: 650 RPQGFAAIRVTLCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGH 709
G + +TL + Q E L ++VE L + A P ++L +++V+ +
Sbjct: 922 HSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPHVYLQSSQVEVRN 979
Query: 710 CFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLE 769
+L P + T+ L N LP + + + + + G++ PS + L L
Sbjct: 980 LYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSEECQLKLELT 1039
Query: 770 TQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYV----------------HPNQ-- 811
E PLV + +G + + HP +
Sbjct: 1040 AHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCSTEQWPGHPKELR 1099
Query: 812 VDFGNIYVLKDS-SRILNLCNQSFIPAFF 839
+DFG+ L+ +R L L N+S I F
Sbjct: 1100 LDFGSAVPLRTRVTRQLILTNRSPIRTRF 1128
Score = 39.3 bits (90), Expect = 0.019
Identities = 33/155 (21%), Positives = 69/155 (44%), Gaps = 9/155 (5%)
Query: 753 SGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHPNQV 812
+GVI PS L V G + I S P +V H+++ +GP + ++ + +
Sbjct: 808 TGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSP-VVLHIEAVFKGPALIINVSAL 866
Query: 813 DFGNIYVLKDSSRILNLCNQSFIPAFFQAHMA--------HKKSLWTIEPNEGMVPPETD 864
FG + + + ++ + + N S +PA ++ + S + IEP+ G + +
Sbjct: 867 QFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHSLGE 926
Query: 865 VQLALTANLNDTLTFKDCVILDIENSSTYRIPVQA 899
++ +T + + L++EN + +PV A
Sbjct: 927 CRVDITLEALHCQHLETVLELEVENGAWSYLPVYA 961
>gi|90669194 deleted in lung and esophageal cancer 1 isoform DLEC1-N1
[Homo sapiens]
Length = 1755
Score = 118 bits (296), Expect = 2e-26
Identities = 172/809 (21%), Positives = 307/809 (37%), Gaps = 111/809 (13%)
Query: 94 DQALFQPFPSEIIFQNYTPCEVYEVPLILRNNDKIPRLVKVVEESSPYFKV---ISPKDI 150
D +F P F +Y VYE+ + L+N R ++V+ S+PYF + + P
Sbjct: 368 DTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGK- 426
Query: 151 GHKVAPGVPSIFRILFTPEENKDYAHTLTCVTE-REKFIVPIKARGARAILDFPDKLNFS 209
G VAPG+ + + F P+ D+ + T+ ++P++AR +L L+
Sbjct: 427 GGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCG 486
Query: 210 TCPVKYSTQKILLVRNIGNKNAVFHI--KTC-----------------RPFSIEPAIGTL 250
C + + +N+G F I KT PF I P++ L
Sbjct: 487 YCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFEL 546
Query: 251 NVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLTIEKTY 310
G ++ +EV F P+S+G I+ D + L I I LD ++ EK+
Sbjct: 547 APGHAILVEVLFSPKSLGKAEQTFIIMCDNCQ--IKELVTIGIGQLIALDLIYISGEKSQ 604
Query: 311 ISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDETDEFFEECIT 370
+T HF+ + E + + A LI + F I
Sbjct: 605 PDPGELTDLTAQ-------HFI------RFEPENLRSTARKQLIIRNATHVELAFYWQIM 651
Query: 371 DPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEA 430
P L+ + TF+ D + F++ P +G + P++ E + F+P E
Sbjct: 652 KPNLQPLMP--GETFSMDSIKCYPDKE----TAFSIMPRKGVLSPHTDHEFILSFSPHEL 705
Query: 431 KLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHCYEAIL----- 485
+ + + ++ E+ P+ + E +G + +++ + GS ++ +L
Sbjct: 706 RDFHSVL--QMVLEEVPEPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYAL 763
Query: 486 ------YNKGSIDALFNMTPPTSA--------LGACFVF--SPKEGIIEPSGVQAIQISF 529
Y ++ F M + + + C + P G+IEPS V +++F
Sbjct: 764 IIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNF 823
Query: 530 SSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSL 589
+ + G ++ L + SP PV L I GP NV AL FG + G T +
Sbjct: 824 TGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQI 883
Query: 590 NNTSLIPMTYKLRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTI 649
N S +P T++++ + P +E + P F I P G +
Sbjct: 884 RNVSQLPATWRMK--------------------ESPVSLQERPEDVSP--FDIEPSSGQL 921
Query: 650 RPQGFAAIRVTLCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGH 709
G + +TL + Q E L ++VE L + A P ++L +++V+ +
Sbjct: 922 HSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPHVYLQSSQVEVRN 979
Query: 710 CFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLE 769
+L P + T+ L N LP + + + + + G++ PS + L L
Sbjct: 980 LYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSEECQLKLELT 1039
Query: 770 TQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYV----------------HPNQ-- 811
E PLV + +G + + HP +
Sbjct: 1040 AHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCSTEQWPGHPKELR 1099
Query: 812 VDFGNIYVLKDS-SRILNLCNQSFIPAFF 839
+DFG+ L+ +R L L N+S I F
Sbjct: 1100 LDFGSAVPLRTRVTRQLILTNRSPIRTRF 1128
Score = 39.3 bits (90), Expect = 0.019
Identities = 33/155 (21%), Positives = 69/155 (44%), Gaps = 9/155 (5%)
Query: 753 SGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHPNQV 812
+GVI PS L V G + I S P +V H+++ +GP + ++ + +
Sbjct: 808 TGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSP-VVLHIEAVFKGPALIINVSAL 866
Query: 813 DFGNIYVLKDSSRILNLCNQSFIPAFFQAHMA--------HKKSLWTIEPNEGMVPPETD 864
FG + + + ++ + + N S +PA ++ + S + IEP+ G + +
Sbjct: 867 QFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHSLGE 926
Query: 865 VQLALTANLNDTLTFKDCVILDIENSSTYRIPVQA 899
++ +T + + L++EN + +PV A
Sbjct: 927 CRVDITLEALHCQHLETVLELEVENGAWSYLPVYA 961
>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
sapiens]
Length = 1925
Score = 60.8 bits (146), Expect = 6e-09
Identities = 53/242 (21%), Positives = 99/242 (40%), Gaps = 19/242 (7%)
Query: 120 LILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLT 179
L+L+N + +K + +F + P+ I ++PG+ I+F P E K+Y L
Sbjct: 166 LVLKNRSLKLQKMKYRPPKTKFFFTVIPQPIF--LSPGITLTLPIVFRPLEAKEYMDQLW 223
Query: 180 CVTEREKFIVPIKAR-GARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTC 238
F V ++A ++ P L C V +T+ + N+G+ F +
Sbjct: 224 FEKAEGMFCVGLRATLPCHRLICRPPSLQLPMCAVGDTTEAFFCLDNVGDLPTFFTWEFS 283
Query: 239 RPFSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAI----- 293
PF + PA G L G++ Q++V F+P + + + Y G + S+ A+
Sbjct: 284 SPFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQ 343
Query: 294 -----------DMNIRLDKNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEE 342
D + + L + ++R I +HN S + A F ++ + E
Sbjct: 344 LLVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAE 403
Query: 343 DR 344
D+
Sbjct: 404 DQ 405
Score = 35.4 bits (80), Expect = 0.27
Identities = 42/199 (21%), Positives = 78/199 (39%), Gaps = 18/199 (9%)
Query: 400 FNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQ--------------QTIYCDILGRE 445
F++ F + P G + P +++I V F PL A +Y+ +I + +
Sbjct: 282 FSSPFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKC 341
Query: 446 IRLPLRIKGEGMGPKIHFNFE-LLDIGKVFTGSAHCYEAILYNKGSIDALF--NMTPPTS 502
+L + IK + + F+ LL G V G + L+N +++A F ++P
Sbjct: 342 AQLLVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDEL 401
Query: 503 ALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEEFL-VNVNGSPEPVKLTIRGCVI 561
A F GI+ P + + + F L ++ + +G L + G
Sbjct: 402 AEDQAFSCPTAHGIVLPGEKKCVSVFFHPKTLDTRTVDYCSIMPSGCASKTLLKVVGFCR 461
Query: 562 GPTFHFNVPALHFGDVSFG 580
GP ++F V+ G
Sbjct: 462 GPAVSLQHYCVNFSWVNLG 480
Score = 35.4 bits (80), Expect = 0.27
Identities = 55/235 (23%), Positives = 93/235 (39%), Gaps = 20/235 (8%)
Query: 640 FTISPDCGTIRPQGFAAIRVTLCSNTVQKYELALVVDVEGIGE------EVLALLITARC 693
F + P G + P + I+VT T YE+ G G ++ A+ A+
Sbjct: 286 FQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWY-GAGSRQRSSIQLQAVAKCAQL 344
Query: 694 VVPALHLVNTEVD---------FGHCFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPT 744
+V H + D FG + E+ ++L N + + ++ E
Sbjct: 345 LVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAED 404
Query: 745 VLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAG--EG 802
FS PT G++ P + + + T + R+ Y SI S LK G G
Sbjct: 405 QAFSCPTAHGIVLPGEKKCVSVFFHPK-TLDTRTVDYCSIMPSGCASKTL-LKVVGFCRG 462
Query: 803 PVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQAHMAHKKSLWTIEPNEG 857
P + + V+F + + + S + L + NQS A FQ + +S++TI P G
Sbjct: 463 PAVSLQHYCVNFSWVNLGERSEQPLWIENQSDCTAHFQFAIDCLESVFTIRPAFG 517
Score = 35.4 bits (80), Expect = 0.27
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 391 LVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPL 450
L Q K F + +F +G++ P S+A + F+P+EAK Y + ILG L +
Sbjct: 1340 LSQVQEKNFDHPIFCCLNPKGEIQPGSTARVLWIFSPIEAKTYTVDVPIHILGWNSAL-I 1398
Query: 451 RIKGEGMGP 459
+G G P
Sbjct: 1399 HFQGVGYNP 1407
>gi|90963001 hypothetical protein LOC170063 [Homo sapiens]
Length = 976
Score = 42.0 bits (97), Expect = 0.003
Identities = 65/333 (19%), Positives = 133/333 (39%), Gaps = 35/333 (10%)
Query: 102 PSEIIFQNYTPCEVYEVPLILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSI 161
P+E+ F + VY +P+ + N + + ++ E P FK++ + ++A G+
Sbjct: 44 PAEVKFLDTMAGRVYRLPITVHNICRWNQKIRFKEPVKPQFKLML-TSLDKELASGLQMT 102
Query: 162 FRILFTPEENKDYAHTLTCVTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYST-QKI 220
+ + P++++D L E + +P+ L+ +NF T K
Sbjct: 103 AMVEYHPDKDEDTFDRLLISIENKTTEIPLIGLIPSCQLEIESVVNFGTLVANSKVYSKE 162
Query: 221 LLVRNIGNKNAVFHIK--TCRPFSIEPAIGTLNVGESMQLEVEF---EPQSVGDHSGRLI 275
+ + N G +F + P I P G ++ SM ++V+F +P+ V + + I
Sbjct: 163 ITITNHGKAPGIFKAEYHGQLPILIFPTSGIVDAKSSMVIKVDFCADQPRIVDEEA---I 219
Query: 276 VCYDTGEKVFVSLYGAAIDMNIRLDKNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKV 335
V ++ +S+ ++ I L +S+++ R + HF
Sbjct: 220 VILQGQPEMLLSIKAHVVEQIIEL-----------LSMSSDRRLE-------CIHFGPVF 261
Query: 336 FATQQEEDREKYRACDDLIK-EEKDETDEFFEECITDPLLREHLSVLSRTFANQRRLVQG 394
F + + + Y + I + D EE TD R +++ + T+ R++
Sbjct: 262 FGSSKIKHARVYNNSPEPINWVAIIQDDAVGEELGTDIQQRTDIALNNLTYI--RKIKNI 319
Query: 395 DSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNP 427
D+ + + + P EG + P IT F P
Sbjct: 320 DTTI----IISCLPNEGTLQPYQKTVITFCFTP 348
Score = 38.9 bits (89), Expect = 0.025
Identities = 39/162 (24%), Positives = 67/162 (41%), Gaps = 16/162 (9%)
Query: 512 PKEGIIEPSGVQAIQISFSSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHF---- 567
P GI++ I++ F + +EE +V + G PE + L+I+ V+
Sbjct: 189 PTSGIVDAKSSMVIKVDFCADQPRIVDEEAIVILQGQPE-MLLSIKAHVVEQIIELLSMS 247
Query: 568 ---NVPALHFGDVSFGFPHTLICSLNNTSLIPMTYKLRIPGDGLGHKSISYCEQHVDYKR 624
+ +HFG V FG + N S P+ + I D +G + + +Q D
Sbjct: 248 SDRRLECIHFGPVFFGSSKIKHARVYNNSPEPINWVAIIQDDAVGEELGTDIQQRTDIAL 307
Query: 625 PSWTKEEISSMKPKEFTISPDC----GTIRPQGFAAIRVTLC 662
+ T I +K + TI C GT++P + +T C
Sbjct: 308 NNLT--YIRKIKNIDTTIIISCLPNEGTLQP--YQKTVITFC 345
>gi|50811889 centrosomal protein 192kDa [Homo sapiens]
Length = 1941
Score = 35.4 bits (80), Expect = 0.27
Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
Query: 196 ARAILDFPDKLNFSTCPVKYS-TQKILLVRNIGNKNAVFHIKTCRPFSIEPAIGTLNVGE 254
AR + D F V S T K+ L N +++ + PF ++ + +L
Sbjct: 1840 ARGVYAPEDVYRFRPTSVGESRTLKVNLRNNSFITHSLKFLSPREPFYVKHSKYSLRAQH 1899
Query: 255 SMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMN 296
+ + V+F+P+S G L++ D G+ + + L G A+ N
Sbjct: 1900 YINMPVQFKPKSAGKFEALLVIQTDEGKSIAIRLIGEALGKN 1941
>gi|122937416 hypothetical protein LOC85452 [Homo sapiens]
Length = 762
Score = 34.7 bits (78), Expect = 0.47
Identities = 32/140 (22%), Positives = 59/140 (42%), Gaps = 6/140 (4%)
Query: 98 FQPFPSEIIFQNYTPCEVYEVPLILRNND---KIPRLVKVVEESSPYFKVISPKDIGHKV 154
F P + FQ++ +VY+ + L N +LV V E + V D +
Sbjct: 515 FNSKPELLHFQDFDIGKVYKKKITLVNTTYTINYCKLVGVEEHLRDFIHV--DFDPPGPL 572
Query: 155 APGVPSIFRILFTPEENKDYAHTLTCVTEREKFIVPIKARGARAILDFPDKL-NFSTCPV 213
+ G+ + F P NKD ++ + + +F VP+K + L +L +F + V
Sbjct: 573 SAGMSCEVLVTFKPMINKDLEGNISFLAQTGEFSVPLKCSTKKCSLSLDKELIDFGSYVV 632
Query: 214 KYSTQKILLVRNIGNKNAVF 233
+T + + + N+G F
Sbjct: 633 GETTSRTITLTNVGGLGTTF 652
Score = 33.1 bits (74), Expect = 1.4
Identities = 34/133 (25%), Positives = 53/133 (39%), Gaps = 19/133 (14%)
Query: 203 PDKLNFSTCPV-KYSTQKILLVRNIGNKNAVFHIKTCRPFSIEPAI-----------GTL 250
P+ L+F + K +KI LV N + I C+ +E + G L
Sbjct: 519 PELLHFQDFDIGKVYKKKITLV------NTTYTINYCKLVGVEEHLRDFIHVDFDPPGPL 572
Query: 251 NVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLTIEKTY 310
+ G S ++ V F+P D G + TGE V L + ++ LDK +
Sbjct: 573 SAGMSCEVLVTFKPMINKDLEGNISFLAQTGE-FSVPLKCSTKKCSLSLDKELIDFGSYV 631
Query: 311 ISLANQRTITIHN 323
+ RTIT+ N
Sbjct: 632 VGETTSRTITLTN 644
>gi|166064027 cyclin-dependent kinase-like 3 isoform 1 [Homo
sapiens]
Length = 592
Score = 33.1 bits (74), Expect = 1.4
Identities = 15/40 (37%), Positives = 23/40 (57%)
Query: 23 GFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTEQR 62
GF K +P L K++ E +VN ++ P E KE L ++R
Sbjct: 290 GFIEKFMPELKAKLLQEAKVNSLIKPKESSKENELRKDER 329
>gi|166064025 cyclin-dependent kinase-like 3 isoform 2 [Homo
sapiens]
Length = 455
Score = 33.1 bits (74), Expect = 1.4
Identities = 15/40 (37%), Positives = 23/40 (57%)
Query: 23 GFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTEQR 62
GF K +P L K++ E +VN ++ P E KE L ++R
Sbjct: 290 GFIEKFMPELKAKLLQEAKVNSLIKPKESSKENELRKDER 329
>gi|157694511 nucleolar complex associated 2 homolog [Homo sapiens]
Length = 749
Score = 32.7 bits (73), Expect = 1.8
Identities = 15/41 (36%), Positives = 25/41 (60%)
Query: 337 ATQQEEDREKYRACDDLIKEEKDETDEFFEECITDPLLREH 377
A +++EDR++++ DL E+D+T+ F E I PL H
Sbjct: 654 ADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRH 694
>gi|33469935 EGF-like, fibronectin type III and laminin G domains
isoform 3 [Homo sapiens]
Length = 375
Score = 32.0 bits (71), Expect = 3.0
Identities = 21/50 (42%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
Query: 256 MQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLT 305
M+ E+ F P S GD G L+ YDTG K F+S+ A + R D S T
Sbjct: 1 MEFEITFRPDS-GD--GVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGT 47
>gi|33469931 EGF-like, fibronectin type III and laminin G domains
isoform 2 [Homo sapiens]
Length = 775
Score = 32.0 bits (71), Expect = 3.0
Identities = 21/50 (42%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
Query: 256 MQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLT 305
M+ E+ F P S GD G L+ YDTG K F+S+ A + R D S T
Sbjct: 401 MEFEITFRPDS-GD--GVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGT 447
>gi|33469929 EGF-like, fibronectin type III and laminin G domains
isoform 1 [Homo sapiens]
Length = 1009
Score = 32.0 bits (71), Expect = 3.0
Identities = 21/50 (42%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
Query: 256 MQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLT 305
M+ E+ F P S GD G L+ YDTG K F+S+ A + R D S T
Sbjct: 635 MEFEITFRPDS-GD--GVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGT 681
>gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]
Length = 1340
Score = 31.6 bits (70), Expect = 4.0
Identities = 15/49 (30%), Positives = 22/49 (44%)
Query: 761 TIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHP 809
T+ +P+ LE Q G++ + F P L H KSA P + P
Sbjct: 936 TLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQP 984
>gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]
Length = 1048
Score = 31.6 bits (70), Expect = 4.0
Identities = 15/49 (30%), Positives = 22/49 (44%)
Query: 761 TIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHP 809
T+ +P+ LE Q G++ + F P L H KSA P + P
Sbjct: 936 TLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQP 984
>gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]
Length = 1037
Score = 31.6 bits (70), Expect = 4.0
Identities = 15/49 (30%), Positives = 22/49 (44%)
Query: 761 TIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHP 809
T+ +P+ LE Q G++ + F P L H KSA P + P
Sbjct: 925 TLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQP 973
>gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
sapiens]
Length = 1021
Score = 31.6 bits (70), Expect = 4.0
Identities = 15/49 (30%), Positives = 22/49 (44%)
Query: 761 TIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHP 809
T+ +P+ LE Q G++ + F P L H KSA P + P
Sbjct: 904 TLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQP 952
>gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens]
Length = 1337
Score = 31.6 bits (70), Expect = 4.0
Identities = 15/49 (30%), Positives = 22/49 (44%)
Query: 761 TIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHP 809
T+ +P+ LE Q G++ + F P L H KSA P + P
Sbjct: 904 TLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQP 952
>gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens]
Length = 1347
Score = 31.6 bits (70), Expect = 4.0
Identities = 15/49 (30%), Positives = 22/49 (44%)
Query: 761 TIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHP 809
T+ +P+ LE Q G++ + F P L H KSA P + P
Sbjct: 904 TLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQP 952
>gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo
sapiens]
Length = 1025
Score = 31.6 bits (70), Expect = 4.0
Identities = 15/49 (30%), Positives = 22/49 (44%)
Query: 761 TIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHP 809
T+ +P+ LE Q G++ + F P L H KSA P + P
Sbjct: 904 TLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQP 952
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,176,463
Number of Sequences: 37866
Number of extensions: 2013156
Number of successful extensions: 4818
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 4675
Number of HSP's gapped (non-prelim): 91
length of query: 1017
length of database: 18,247,518
effective HSP length: 112
effective length of query: 905
effective length of database: 14,006,526
effective search space: 12675906030
effective search space used: 12675906030
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.