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Search of human proteins with 46255047
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46255047 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]
(433 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46255049 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens] 899 0.0
gi|46255047 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens] 899 0.0
gi|223556010 protein arginine methyltransferase 3 isoform 3 [Hom... 214 9e-56
gi|223556008 protein arginine methyltransferase 3 isoform 2 [Hom... 214 9e-56
gi|44771198 protein arginine methyltransferase 3 isoform 1 [Homo... 214 9e-56
gi|154759421 HMT1 hnRNP methyltransferase-like 2 isoform 1 [Homo... 210 2e-54
gi|151301219 HMT1 hnRNP methyltransferase-like 2 isoform 3 [Homo... 210 2e-54
gi|150456457 HMT1 hnRNP methyltransferase-like 2 isoform 2 [Homo... 210 2e-54
gi|74099699 HMT1 hnRNP methyltransferase-like 4 [Homo sapiens] 206 3e-53
gi|227908867 protein arginine methyltransferase 6 [Homo sapiens] 205 7e-53
gi|40288288 coactivator-associated arginine methyltransferase 1 ... 175 6e-44
gi|40538772 protein arginine methyltransferase 10 (putative) [Ho... 60 3e-09
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap... 59 9e-09
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi... 59 9e-09
gi|23510364 protein-tyrosine kinase fyn isoform c [Homo sapiens] 57 3e-08
gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens] 57 3e-08
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens] 57 3e-08
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 56 7e-08
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 56 7e-08
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 56 7e-08
gi|112382244 proto-oncogene tyrosine-protein kinase FGR [Homo sa... 54 2e-07
gi|112382241 proto-oncogene tyrosine-protein kinase FGR [Homo sa... 54 2e-07
gi|4885235 proto-oncogene tyrosine-protein kinase FGR [Homo sapi... 54 2e-07
gi|88900507 protein arginine methyltransferase 5 isoform b [Homo... 54 4e-07
gi|20070220 protein arginine methyltransferase 5 isoform a [Homo... 54 4e-07
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens] 53 5e-07
gi|9506615 protein arginine methyltransferase 7 [Homo sapiens] 52 1e-06
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 49 9e-06
gi|15011979 Rho guanine nucleotide exchange factor 4 isoform a [... 47 3e-05
gi|15011981 Rho guanine nucleotide exchange factor 4 isoform b [... 47 3e-05
>gi|46255049 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]
Length = 433
Score = 899 bits (2322), Expect = 0.0
Identities = 433/433 (100%), Positives = 433/433 (100%)
Query: 1 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILIL 60
MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILIL
Sbjct: 1 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILIL 60
Query: 61 RQTTADWWWGERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQP 120
RQTTADWWWGERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQP
Sbjct: 61 RQTTADWWWGERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQP 120
Query: 121 RTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV 180
RTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV
Sbjct: 121 RTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV 180
Query: 181 LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVI 240
LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVI
Sbjct: 181 LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVI 240
Query: 241 WPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCL 300
WPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCL
Sbjct: 241 WPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCL 300
Query: 301 SEPCTILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLS 360
SEPCTILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLS
Sbjct: 301 SEPCTILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLS 360
Query: 361 TGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSRQDPT 420
TGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSRQDPT
Sbjct: 361 TGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSRQDPT 420
Query: 421 SQKVGEKVFPIWR 433
SQKVGEKVFPIWR
Sbjct: 421 SQKVGEKVFPIWR 433
>gi|46255047 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]
Length = 433
Score = 899 bits (2322), Expect = 0.0
Identities = 433/433 (100%), Positives = 433/433 (100%)
Query: 1 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILIL 60
MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILIL
Sbjct: 1 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILIL 60
Query: 61 RQTTADWWWGERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQP 120
RQTTADWWWGERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQP
Sbjct: 61 RQTTADWWWGERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQP 120
Query: 121 RTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV 180
RTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV
Sbjct: 121 RTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV 180
Query: 181 LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVI 240
LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVI
Sbjct: 181 LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVI 240
Query: 241 WPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCL 300
WPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCL
Sbjct: 241 WPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCL 300
Query: 301 SEPCTILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLS 360
SEPCTILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLS
Sbjct: 301 SEPCTILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLS 360
Query: 361 TGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSRQDPT 420
TGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSRQDPT
Sbjct: 361 TGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSRQDPT 420
Query: 421 SQKVGEKVFPIWR 433
SQKVGEKVFPIWR
Sbjct: 421 SQKVGEKVFPIWR 433
>gi|223556010 protein arginine methyltransferase 3 isoform 3 [Homo
sapiens]
Length = 454
Score = 214 bits (546), Expect = 9e-56
Identities = 119/319 (37%), Positives = 178/319 (55%), Gaps = 12/319 (3%)
Query: 95 DTWQDEE--YFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIIS 152
D +DE+ YF SYG +H EML D+ RT Y I QN DKV+LDVGCGTGI+S
Sbjct: 134 DLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILS 193
Query: 153 LFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLP-EKVDVLVSE 211
+F A A + V V+ SE+ ++ N D IT+ + K+E+V LP EKVDV++SE
Sbjct: 194 MFAAK-AGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISE 252
Query: 212 WMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEF 271
WMG LLFE M++S+LYA++ +L + G ++P + + LV S + ++ FWD+ Y F
Sbjct: 253 WMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGF 312
Query: 272 NLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGELRFDIR 331
+S +K + E + +L P+ +SEPC I +D T ISDLE + I
Sbjct: 313 KMSCMKKAVIPEAVVE-----VLDPKTLISEPCGIKHIDCHTTSISDLE-FSSDFTLKIT 366
Query: 332 KAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTG 391
+ +F ++F+ + V STGP THWKQT+F+++ P V G+ + G
Sbjct: 367 RTSMCTAIAGYFDIYFEKNCHNR--VVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKG 424
Query: 392 SVVLQRNPVWRRHMSVALS 410
V + +N R ++V L+
Sbjct: 425 KVTVHKNKKDPRSLTVTLT 443
>gi|223556008 protein arginine methyltransferase 3 isoform 2 [Homo
sapiens]
Length = 469
Score = 214 bits (546), Expect = 9e-56
Identities = 119/319 (37%), Positives = 178/319 (55%), Gaps = 12/319 (3%)
Query: 95 DTWQDEE--YFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIIS 152
D +DE+ YF SYG +H EML D+ RT Y I QN DKV+LDVGCGTGI+S
Sbjct: 149 DLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILS 208
Query: 153 LFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLP-EKVDVLVSE 211
+F A A + V V+ SE+ ++ N D IT+ + K+E+V LP EKVDV++SE
Sbjct: 209 MFAAK-AGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISE 267
Query: 212 WMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEF 271
WMG LLFE M++S+LYA++ +L + G ++P + + LV S + ++ FWD+ Y F
Sbjct: 268 WMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGF 327
Query: 272 NLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGELRFDIR 331
+S +K + E + +L P+ +SEPC I +D T ISDLE + I
Sbjct: 328 KMSCMKKAVIPEAVVE-----VLDPKTLISEPCGIKHIDCHTTSISDLE-FSSDFTLKIT 381
Query: 332 KAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTG 391
+ +F ++F+ + V STGP THWKQT+F+++ P V G+ + G
Sbjct: 382 RTSMCTAIAGYFDIYFEKNCHNR--VVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKG 439
Query: 392 SVVLQRNPVWRRHMSVALS 410
V + +N R ++V L+
Sbjct: 440 KVTVHKNKKDPRSLTVTLT 458
>gi|44771198 protein arginine methyltransferase 3 isoform 1 [Homo
sapiens]
Length = 531
Score = 214 bits (546), Expect = 9e-56
Identities = 119/319 (37%), Positives = 178/319 (55%), Gaps = 12/319 (3%)
Query: 95 DTWQDEE--YFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIIS 152
D +DE+ YF SYG +H EML D+ RT Y I QN DKV+LDVGCGTGI+S
Sbjct: 211 DLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILS 270
Query: 153 LFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLP-EKVDVLVSE 211
+F A A + V V+ SE+ ++ N D IT+ + K+E+V LP EKVDV++SE
Sbjct: 271 MFAAK-AGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISE 329
Query: 212 WMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEF 271
WMG LLFE M++S+LYA++ +L + G ++P + + LV S + ++ FWD+ Y F
Sbjct: 330 WMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGF 389
Query: 272 NLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGELRFDIR 331
+S +K + E + +L P+ +SEPC I +D T ISDLE + I
Sbjct: 390 KMSCMKKAVIPEAVVE-----VLDPKTLISEPCGIKHIDCHTTSISDLE-FSSDFTLKIT 443
Query: 332 KAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTG 391
+ +F ++F+ + V STGP THWKQT+F+++ P V G+ + G
Sbjct: 444 RTSMCTAIAGYFDIYFEKNCHNR--VVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKG 501
Query: 392 SVVLQRNPVWRRHMSVALS 410
V + +N R ++V L+
Sbjct: 502 KVTVHKNKKDPRSLTVTLT 520
>gi|154759421 HMT1 hnRNP methyltransferase-like 2 isoform 1 [Homo
sapiens]
Length = 371
Score = 210 bits (535), Expect = 2e-54
Identities = 112/307 (36%), Positives = 179/307 (58%), Gaps = 13/307 (4%)
Query: 94 EDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISL 153
ED + YF SY +H EML D+ RT Y + + N+ DKV+LDVG GTGI+ +
Sbjct: 45 EDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCM 104
Query: 154 FCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLP-EKVDVLVSEW 212
F A A R V +E S ++ + ++V N ++T+ + KVE+V LP EKVD+++SEW
Sbjct: 105 FAAK-AGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEW 163
Query: 213 MGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRS-KVLFWDNAYEF 271
MG CL +E M+ ++LYARD WL DG+I+P A L+ V D+ Y+ K+ +W+N Y F
Sbjct: 164 MGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLY-VTAIEDRQYKDYKIHWWENVYGF 222
Query: 272 NLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGELRFDIR 331
++S +K +A+KE ++ P+ ++ C I ++D+ TV++ DL T ++
Sbjct: 223 DMSCIKDVAIKE-----PLVDVVDPKQLVTNACLIKEVDIYTVKVEDL-TFTSPFCLQVK 276
Query: 332 KAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTG 391
+ +H A+F++ F + ST P P THWKQT+F M+D + V TG+ + G
Sbjct: 277 RNDYVHALVAYFNIEFTRCHKRTG---FSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFG 333
Query: 392 SVVLQRN 398
++ ++ N
Sbjct: 334 TIGMRPN 340
>gi|151301219 HMT1 hnRNP methyltransferase-like 2 isoform 3 [Homo
sapiens]
Length = 353
Score = 210 bits (535), Expect = 2e-54
Identities = 112/307 (36%), Positives = 179/307 (58%), Gaps = 13/307 (4%)
Query: 94 EDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISL 153
ED + YF SY +H EML D+ RT Y + + N+ DKV+LDVG GTGI+ +
Sbjct: 27 EDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCM 86
Query: 154 FCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLP-EKVDVLVSEW 212
F A A R V +E S ++ + ++V N ++T+ + KVE+V LP EKVD+++SEW
Sbjct: 87 FAAK-AGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEW 145
Query: 213 MGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRS-KVLFWDNAYEF 271
MG CL +E M+ ++LYARD WL DG+I+P A L+ V D+ Y+ K+ +W+N Y F
Sbjct: 146 MGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLY-VTAIEDRQYKDYKIHWWENVYGF 204
Query: 272 NLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGELRFDIR 331
++S +K +A+KE ++ P+ ++ C I ++D+ TV++ DL T ++
Sbjct: 205 DMSCIKDVAIKE-----PLVDVVDPKQLVTNACLIKEVDIYTVKVEDL-TFTSPFCLQVK 258
Query: 332 KAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTG 391
+ +H A+F++ F + ST P P THWKQT+F M+D + V TG+ + G
Sbjct: 259 RNDYVHALVAYFNIEFTRCHKRTG---FSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFG 315
Query: 392 SVVLQRN 398
++ ++ N
Sbjct: 316 TIGMRPN 322
>gi|150456457 HMT1 hnRNP methyltransferase-like 2 isoform 2 [Homo
sapiens]
Length = 347
Score = 210 bits (535), Expect = 2e-54
Identities = 112/307 (36%), Positives = 179/307 (58%), Gaps = 13/307 (4%)
Query: 94 EDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISL 153
ED + YF SY +H EML D+ RT Y + + N+ DKV+LDVG GTGI+ +
Sbjct: 21 EDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCM 80
Query: 154 FCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLP-EKVDVLVSEW 212
F A A R V +E S ++ + ++V N ++T+ + KVE+V LP EKVD+++SEW
Sbjct: 81 FAAK-AGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEW 139
Query: 213 MGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRS-KVLFWDNAYEF 271
MG CL +E M+ ++LYARD WL DG+I+P A L+ V D+ Y+ K+ +W+N Y F
Sbjct: 140 MGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLY-VTAIEDRQYKDYKIHWWENVYGF 198
Query: 272 NLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGELRFDIR 331
++S +K +A+KE ++ P+ ++ C I ++D+ TV++ DL T ++
Sbjct: 199 DMSCIKDVAIKE-----PLVDVVDPKQLVTNACLIKEVDIYTVKVEDL-TFTSPFCLQVK 252
Query: 332 KAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTG 391
+ +H A+F++ F + ST P P THWKQT+F M+D + V TG+ + G
Sbjct: 253 RNDYVHALVAYFNIEFTRCHKRTG---FSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFG 309
Query: 392 SVVLQRN 398
++ ++ N
Sbjct: 310 TIGMRPN 316
>gi|74099699 HMT1 hnRNP methyltransferase-like 4 [Homo sapiens]
Length = 394
Score = 206 bits (525), Expect = 3e-53
Identities = 109/316 (34%), Positives = 187/316 (59%), Gaps = 13/316 (4%)
Query: 85 GKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDV 144
GK +PE+ + YF SY +H EML D+ RT Y + + NK DKV+LDV
Sbjct: 59 GKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDV 118
Query: 145 GCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLP-E 203
G GTGI+S+F A A + V+ +E S ++ ++ +++ N +IIT+++ KVE+V LP E
Sbjct: 119 GSGTGILSMFAAK-AGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVE 177
Query: 204 KVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRS-KV 262
KVD+++SEWMG CL +E M+ ++++ARD WLK G+++P AAL++V D+ Y+ K+
Sbjct: 178 KVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIE-DRQYKDFKI 236
Query: 263 LFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETL 322
+W+N Y F+++ ++ +A+KE I+ P+ ++ C I ++D+ TV+ +L +
Sbjct: 237 HWWENVYGFDMTCIRDVAMKE-----PLVDIVDPKQVVTNACLIKEVDIYTVKTEEL-SF 290
Query: 323 RGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVP 382
I++ +H +F++ F + ST P P THWKQT+F ++D +
Sbjct: 291 TSAFCLQIQRNDYVHALVTYFNIEFTKCHK---KMGFSTAPDAPYTHWKQTVFYLEDYLT 347
Query: 383 VHTGDVVTGSVVLQRN 398
V G+ + G++ ++ N
Sbjct: 348 VRRGEEIYGTISMKPN 363
>gi|227908867 protein arginine methyltransferase 6 [Homo sapiens]
Length = 375
Score = 205 bits (521), Expect = 7e-53
Identities = 127/329 (38%), Positives = 179/329 (54%), Gaps = 9/329 (2%)
Query: 98 QDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAH 157
+D+ Y+ Y + +H EM+AD+ RT Y IL+N +L K +LDVG GTGI+S+FCA
Sbjct: 43 RDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQ 102
Query: 158 YARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCL 217
A R VYAVEAS + Q ++V NG D + V VE V LPE+VD +VSEWMG L
Sbjct: 103 -AGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGL 161
Query: 218 LFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNA---YEFNLS 274
L E M+ S+L+AR WLKE G++ P A L + P S D+ ++ FW Y ++S
Sbjct: 162 LHESMLSSVLHARTKWLKEGGLLLPASAELFIAPIS-DQMLEWRLGFWSQVKQHYGVDMS 220
Query: 275 ALKSLAVKEFFSKPK-YNHILKPEDCLSEPCTILQLDMRTVQI-SDLET-LRGELRFDIR 331
L+ A + + L ED L+ P QL++ + +LE + G R
Sbjct: 221 CLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCY 280
Query: 332 KAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTG 391
+ +HGF WF V F E + P VLST PFHP THWKQ L +++PV V V+G
Sbjct: 281 GSAPMHGFAIWFQVTFPG-GESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSG 339
Query: 392 SVVLQRNPVWRRHMSVALSWAVTSRQDPT 420
+ L + R + V L + V +++ T
Sbjct: 340 EITLLPSRDNPRRLRVLLRYKVGDQEEKT 368
>gi|40288288 coactivator-associated arginine methyltransferase 1
[Homo sapiens]
Length = 608
Score = 175 bits (444), Expect = 6e-44
Identities = 116/305 (38%), Positives = 163/305 (53%), Gaps = 16/305 (5%)
Query: 101 EYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYAR 160
+YF YG L M+ D RT Y ILQN DK++LDVGCG+GI+S F A A
Sbjct: 148 QYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQ-AG 206
Query: 161 PRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFE 220
R +YAVEAS MAQH LV N D I V KVE+V LPE+VD+++SE MG L E
Sbjct: 207 ARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNE 266
Query: 221 FMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYR---SKVLFW--DNAYEFNLSA 275
M+ES L+A+ +LK G ++PT+ +HL P + ++ Y +K FW + + +LSA
Sbjct: 267 RMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSA 325
Query: 276 LKSLAVKEFFSKPKYNHI-LKPEDCLSEPCTILQLDMRTVQISDLETLRGELRFDIRKAG 334
L+ AV E+F +P + ++ S T+ L+ + DL + +F + +G
Sbjct: 326 LRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKE---GDLHRIEIPFKFHMLHSG 382
Query: 335 TLHGFTAWFSVHFQSLQEGQPPQV-LSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSV 393
+HG WF V F G V LST P P THW Q + P+ GD ++G+
Sbjct: 383 LVHGLAFWFDVAF----IGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTC 438
Query: 394 VLQRN 398
+L N
Sbjct: 439 LLIAN 443
>gi|40538772 protein arginine methyltransferase 10 (putative) [Homo
sapiens]
Length = 845
Score = 60.5 bits (145), Expect = 3e-09
Identities = 76/302 (25%), Positives = 128/302 (42%), Gaps = 47/302 (15%)
Query: 112 HLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASE 171
H ML D R T Y++ I Q L K +LD+G GTGI+S+F A A +VYA E S+
Sbjct: 153 HFIMLNDTKRNTIYNAAI-QKAVCLGSKSVLDIGAGTGILSMF-AKKAGAHSVYACELSK 210
Query: 172 -MAQHTGQLVLQNGFADIITVYQQKVEDVV----LPEKVDVLVSEWMGTCLLFEFMIESI 226
M + +V N I + K D+ +PE+V ++V+E + L E ++ES+
Sbjct: 211 TMYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESL 270
Query: 227 LYA------------RDAWLKEDGVIWPTMAALH--LVPCSADKDYR------------- 259
++A A ++ G + P A + V C+ + +
Sbjct: 271 IHAWEHLLLQPKTKGESANCEKYGKVIPASAVIFGMAVECAEIRRHHRVGIKDIAGIHLP 330
Query: 260 SKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQ-ISD 318
+ V F AY S++ + E ++ K + + L+E I+ +D +Q +
Sbjct: 331 TNVKFQSPAY----SSVDTEETIEPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKS 386
Query: 319 LETLR-GELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMM 377
L T + ++ + K G L WF + LST P T W+Q ++ +
Sbjct: 387 LATKKPDKIGIPVIKEGILDAIMVWFVLQLDD------EHSLSTSPSEETC-WEQAVYPV 439
Query: 378 DD 379
D
Sbjct: 440 QD 441
Score = 39.3 bits (90), Expect = 0.007
Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 11/94 (11%)
Query: 300 LSEPCTILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVL 359
LS+P +L+LD+ T L T E++ + K+G L W+ ++ + +
Sbjct: 750 LSKPVELLRLDLMTPY---LNTSNREVKVYVCKSGRLTAIPFWYHMYLD--------EEI 798
Query: 360 STGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSV 393
+HWKQ ++D+P+ V G+ + S+
Sbjct: 799 RLDTSSEASHWKQAAVVLDNPIQVEMGEELVLSI 832
>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 58.9 bits (141), Expect = 9e-09
Identities = 42/105 (40%), Positives = 54/105 (51%), Gaps = 13/105 (12%)
Query: 23 AGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE--RAGCCGYIP 80
AG L GV FVA+ DY + ET LSF +GE++ I+ T DWW G GYIP
Sbjct: 79 AGPLAGGVTT--FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIP 136
Query: 81 ANHVGKHVDEYDPEDTWQDEE-YFGSYGTLKLHLEML-ADQPRTT 123
+N+V P D+ Q EE YFG + +L A+ PR T
Sbjct: 137 SNYVA-------PSDSIQAEEWYFGKITRRESERLLLNAENPRGT 174
>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 58.9 bits (141), Expect = 9e-09
Identities = 42/105 (40%), Positives = 54/105 (51%), Gaps = 13/105 (12%)
Query: 23 AGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE--RAGCCGYIP 80
AG L GV FVA+ DY + ET LSF +GE++ I+ T DWW G GYIP
Sbjct: 79 AGPLAGGVTT--FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIP 136
Query: 81 ANHVGKHVDEYDPEDTWQDEE-YFGSYGTLKLHLEML-ADQPRTT 123
+N+V P D+ Q EE YFG + +L A+ PR T
Sbjct: 137 SNYVA-------PSDSIQAEEWYFGKITRRESERLLLNAENPRGT 174
>gi|23510364 protein-tyrosine kinase fyn isoform c [Homo sapiens]
Length = 482
Score = 57.0 bits (136), Expect = 3e-08
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 11/93 (11%)
Query: 35 FVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE--RAGCCGYIPANHVGKHVDEYD 92
FVA+ DY A E LSF +GEK IL + DWW G GYIP+N+V
Sbjct: 87 FVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVA------- 139
Query: 93 PEDTWQDEE-YFGSYGTLKLHLEMLA-DQPRTT 123
P D+ Q EE YFG G ++L+ PR T
Sbjct: 140 PVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGT 172
>gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]
Length = 534
Score = 57.0 bits (136), Expect = 3e-08
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 11/93 (11%)
Query: 35 FVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE--RAGCCGYIPANHVGKHVDEYD 92
FVA+ DY A E LSF +GEK IL + DWW G GYIP+N+V
Sbjct: 87 FVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVA------- 139
Query: 93 PEDTWQDEE-YFGSYGTLKLHLEMLA-DQPRTT 123
P D+ Q EE YFG G ++L+ PR T
Sbjct: 140 PVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGT 172
>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
Length = 537
Score = 57.0 bits (136), Expect = 3e-08
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 11/93 (11%)
Query: 35 FVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE--RAGCCGYIPANHVGKHVDEYD 92
FVA+ DY A E LSF +GEK IL + DWW G GYIP+N+V
Sbjct: 87 FVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVA------- 139
Query: 93 PEDTWQDEE-YFGSYGTLKLHLEMLA-DQPRTT 123
P D+ Q EE YFG G ++L+ PR T
Sbjct: 140 PVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGT 172
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 55.8 bits (133), Expect = 7e-08
Identities = 25/64 (39%), Positives = 38/64 (59%), Gaps = 1/64 (1%)
Query: 34 EFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDEYDP 93
+ +A+ DYAA +E +LSF +G+ I ++ + DWW GE G G P+N+V K + DP
Sbjct: 1104 QVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYV-KMTTDSDP 1162
Query: 94 EDTW 97
W
Sbjct: 1163 SQQW 1166
Score = 43.1 bits (100), Expect = 5e-04
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 18/103 (17%)
Query: 8 PRSESQGEEPAECSEAGLLQEGVQP-----EEFVAIADYAATDETQLSFLRGEKILILRQ 62
P SE + EEP E A + ++ EE++A+ Y++ + L+F GE+IL+ Q
Sbjct: 928 PGSEVKREEP-EALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILV-TQ 985
Query: 63 TTADWWWGERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGS 105
+WW G G P+N+V +D+E FGS
Sbjct: 986 KDGEWWTGSIGDRSGIFPSNYVKP-----------KDQESFGS 1017
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
Query: 31 QPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE-----RAGCCGYIPANHV 84
+PE + Y A+ QLS G+ ILIL++ T+ WW GE + G+ PA+HV
Sbjct: 1027 KPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHV 1085
Score = 34.7 bits (78), Expect = 0.17
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 5/62 (8%)
Query: 37 AIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHV----GKHVDEYD 92
A+ + A + L+F + + I +L Q +WW+GE G G+ P ++V G V +
Sbjct: 878 ALCSWTAKKDNHLNFSKHDIITVLEQQE-NWWFGEVHGGRGWFPKSYVKIIPGSEVKREE 936
Query: 93 PE 94
PE
Sbjct: 937 PE 938
Score = 28.9 bits (63), Expect = 9.5
Identities = 15/52 (28%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 37 AIADYAATDETQLSFLRGEKILILRQTTAD--WWWGERAGCCGYIPANHVGK 86
A+ + A + ++SF G+ I + +T + W +G G G+ P N+V K
Sbjct: 737 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEK 788
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 55.8 bits (133), Expect = 7e-08
Identities = 25/64 (39%), Positives = 38/64 (59%), Gaps = 1/64 (1%)
Query: 34 EFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDEYDP 93
+ +A+ DYAA +E +LSF +G+ I ++ + DWW GE G G P+N+V K + DP
Sbjct: 1131 QVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYV-KMTTDSDP 1189
Query: 94 EDTW 97
W
Sbjct: 1190 SQQW 1193
Score = 43.1 bits (100), Expect = 5e-04
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 18/103 (17%)
Query: 8 PRSESQGEEPAECSEAGLLQEGVQP-----EEFVAIADYAATDETQLSFLRGEKILILRQ 62
P SE + EEP E A + ++ EE++A+ Y++ + L+F GE+IL+ Q
Sbjct: 955 PGSEVKREEP-EALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILV-TQ 1012
Query: 63 TTADWWWGERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGS 105
+WW G G P+N+V +D+E FGS
Sbjct: 1013 KDGEWWTGSIGDRSGIFPSNYVKP-----------KDQESFGS 1044
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
Query: 31 QPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE-----RAGCCGYIPANHV 84
+PE + Y A+ QLS G+ ILIL++ T+ WW GE + G+ PA+HV
Sbjct: 1054 KPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHV 1112
Score = 34.7 bits (78), Expect = 0.17
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 5/62 (8%)
Query: 37 AIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHV----GKHVDEYD 92
A+ + A + L+F + + I +L Q +WW+GE G G+ P ++V G V +
Sbjct: 905 ALCSWTAKKDNHLNFSKHDIITVLEQQE-NWWFGEVHGGRGWFPKSYVKIIPGSEVKREE 963
Query: 93 PE 94
PE
Sbjct: 964 PE 965
Score = 28.9 bits (63), Expect = 9.5
Identities = 15/52 (28%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 37 AIADYAATDETQLSFLRGEKILILRQTTAD--WWWGERAGCCGYIPANHVGK 86
A+ + A + ++SF G+ I + +T + W +G G G+ P N+V K
Sbjct: 764 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEK 815
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 55.8 bits (133), Expect = 7e-08
Identities = 25/64 (39%), Positives = 38/64 (59%), Gaps = 1/64 (1%)
Query: 34 EFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDEYDP 93
+ +A+ DYAA +E +LSF +G+ I ++ + DWW GE G G P+N+V K + DP
Sbjct: 1131 QVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYV-KMTTDSDP 1189
Query: 94 EDTW 97
W
Sbjct: 1190 SQQW 1193
Score = 43.1 bits (100), Expect = 5e-04
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 18/103 (17%)
Query: 8 PRSESQGEEPAECSEAGLLQEGVQP-----EEFVAIADYAATDETQLSFLRGEKILILRQ 62
P SE + EEP E A + ++ EE++A+ Y++ + L+F GE+IL+ Q
Sbjct: 955 PGSEVKREEP-EALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILV-TQ 1012
Query: 63 TTADWWWGERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGS 105
+WW G G P+N+V +D+E FGS
Sbjct: 1013 KDGEWWTGSIGDRSGIFPSNYVKP-----------KDQESFGS 1044
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
Query: 31 QPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE-----RAGCCGYIPANHV 84
+PE + Y A+ QLS G+ ILIL++ T+ WW GE + G+ PA+HV
Sbjct: 1054 KPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHV 1112
Score = 34.7 bits (78), Expect = 0.17
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 5/62 (8%)
Query: 37 AIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHV----GKHVDEYD 92
A+ + A + L+F + + I +L Q +WW+GE G G+ P ++V G V +
Sbjct: 905 ALCSWTAKKDNHLNFSKHDIITVLEQQE-NWWFGEVHGGRGWFPKSYVKIIPGSEVKREE 963
Query: 93 PE 94
PE
Sbjct: 964 PE 965
Score = 28.9 bits (63), Expect = 9.5
Identities = 15/52 (28%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 37 AIADYAATDETQLSFLRGEKILILRQTTAD--WWWGERAGCCGYIPANHVGK 86
A+ + A + ++SF G+ I + +T + W +G G G+ P N+V K
Sbjct: 764 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEK 815
>gi|112382244 proto-oncogene tyrosine-protein kinase FGR [Homo
sapiens]
Length = 529
Score = 54.3 bits (129), Expect = 2e-07
Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 10/92 (10%)
Query: 29 GVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE--RAGCCGYIPANHVGK 86
G+ F+A+ DY A E L+F +GEK IL T DWW +G G IP+N+V
Sbjct: 76 GIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVA- 134
Query: 87 HVDEYDPEDTWQDEE-YFGSYGTLKLHLEMLA 117
P D+ Q EE YFG G ++L+
Sbjct: 135 ------PVDSIQAEEWYFGKIGRKDAERQLLS 160
>gi|112382241 proto-oncogene tyrosine-protein kinase FGR [Homo
sapiens]
Length = 529
Score = 54.3 bits (129), Expect = 2e-07
Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 10/92 (10%)
Query: 29 GVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE--RAGCCGYIPANHVGK 86
G+ F+A+ DY A E L+F +GEK IL T DWW +G G IP+N+V
Sbjct: 76 GIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVA- 134
Query: 87 HVDEYDPEDTWQDEE-YFGSYGTLKLHLEMLA 117
P D+ Q EE YFG G ++L+
Sbjct: 135 ------PVDSIQAEEWYFGKIGRKDAERQLLS 160
>gi|4885235 proto-oncogene tyrosine-protein kinase FGR [Homo
sapiens]
Length = 529
Score = 54.3 bits (129), Expect = 2e-07
Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 10/92 (10%)
Query: 29 GVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE--RAGCCGYIPANHVGK 86
G+ F+A+ DY A E L+F +GEK IL T DWW +G G IP+N+V
Sbjct: 76 GIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVA- 134
Query: 87 HVDEYDPEDTWQDEE-YFGSYGTLKLHLEMLA 117
P D+ Q EE YFG G ++L+
Sbjct: 135 ------PVDSIQAEEWYFGKIGRKDAERQLLS 160
>gi|88900507 protein arginine methyltransferase 5 isoform b [Homo
sapiens]
Length = 620
Score = 53.5 bits (127), Expect = 4e-07
Identities = 75/288 (26%), Positives = 112/288 (38%), Gaps = 38/288 (13%)
Query: 139 KVILDVGCGTGII---SLFCAHYARPRA-VYAVEASEMAQHTGQLVLQNGFADIITVYQQ 194
+V++ +G G G + SL A A R +YAVE + A T + + +TV
Sbjct: 342 QVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSS 401
Query: 195 KVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSA 254
+ + V PEK D++VSE +G+ E E + A+ +LK+DGV P L P S+
Sbjct: 402 DMREWVAPEKADIIVSELLGSFADNELSPECLDGAQH-FLKDDGVSIPGEYTSFLAPISS 460
Query: 255 DKDYRS----KVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLD 310
K Y + D +F + + L S P +PC
Sbjct: 461 SKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAP-------------QPCFTFSHP 507
Query: 311 MRTVQISDLETLRGELRFDIRKAGTLHGFTAWF-SVHFQSLQEGQPPQVLSTGPFHPTTH 369
R I + L F + LHGF +F +V +Q + P+ S G F
Sbjct: 508 NRDPMIDNNRYC--TLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMF----S 561
Query: 370 WKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWR--RHMSVALSWAVTS 415
W LF + P+ V G + WR V WAVT+
Sbjct: 562 WFPILFPIKQPITVREGQTICVR-------FWRCSNSKKVWYEWAVTA 602
>gi|20070220 protein arginine methyltransferase 5 isoform a [Homo
sapiens]
Length = 637
Score = 53.5 bits (127), Expect = 4e-07
Identities = 75/288 (26%), Positives = 112/288 (38%), Gaps = 38/288 (13%)
Query: 139 KVILDVGCGTGII---SLFCAHYARPRA-VYAVEASEMAQHTGQLVLQNGFADIITVYQQ 194
+V++ +G G G + SL A A R +YAVE + A T + + +TV
Sbjct: 359 QVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSS 418
Query: 195 KVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSA 254
+ + V PEK D++VSE +G+ E E + A+ +LK+DGV P L P S+
Sbjct: 419 DMREWVAPEKADIIVSELLGSFADNELSPECLDGAQH-FLKDDGVSIPGEYTSFLAPISS 477
Query: 255 DKDYRS----KVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLD 310
K Y + D +F + + L S P +PC
Sbjct: 478 SKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAP-------------QPCFTFSHP 524
Query: 311 MRTVQISDLETLRGELRFDIRKAGTLHGFTAWF-SVHFQSLQEGQPPQVLSTGPFHPTTH 369
R I + L F + LHGF +F +V +Q + P+ S G F
Sbjct: 525 NRDPMIDNNRYC--TLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMF----S 578
Query: 370 WKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWR--RHMSVALSWAVTS 415
W LF + P+ V G + WR V WAVT+
Sbjct: 579 WFPILFPIKQPITVREGQTICVR-------FWRCSNSKKVWYEWAVTA 619
>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
Length = 543
Score = 53.1 bits (126), Expect = 5e-07
Identities = 32/76 (42%), Positives = 39/76 (51%), Gaps = 10/76 (13%)
Query: 35 FVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE--RAGCCGYIPANHVGKHVDEYD 92
FVA+ DY A LSF +GE+ I+ T DWW G GYIP+N+V
Sbjct: 96 FVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVA------- 148
Query: 93 PEDTWQDEE-YFGSYG 107
P D+ Q EE YFG G
Sbjct: 149 PADSIQAEEWYFGKMG 164
>gi|9506615 protein arginine methyltransferase 7 [Homo sapiens]
Length = 692
Score = 51.6 bits (122), Expect = 1e-06
Identities = 64/263 (24%), Positives = 112/263 (42%), Gaps = 31/263 (11%)
Query: 112 HLEMLADQPRTTKYHSVILQNKESLTDK----VILDVGCGTGIISLFCAHYARPRAVYAV 167
+ +ML D+ R KY+ I + D+ ++LD+G GTG++S+ A A YA+
Sbjct: 35 YADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMM-AVTAGADFCYAI 93
Query: 168 EA-SEMAQHTGQLVLQNGFADIITVYQQKVEDVV------LPEKVDVLVSEWMGTCLLFE 220
E MA ++V +NGF+D I V + +V +P + ++LV+E T L+ E
Sbjct: 94 EVFKPMADAAVKIVEKNGFSDKIKVINKHSTEVTVGPEGDMPCRANILVTELFDTELIGE 153
Query: 221 FMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLA 280
+ S +A ++E+ P A ++ A ++ W+ + ++
Sbjct: 154 GALPSYEHAHRHLVEENCEAVPHRATVY-----AQLVESGRMWSWNKLFPIHVQTSLGEQ 208
Query: 281 VKEFFSKPKYNHILKPEDCLSEP--CTILQLDMRTVQISDLETLRGEL-RFDIRKAGTLH 337
V I+ P D S P ++ + + V +D L L F I + +
Sbjct: 209 V-----------IVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSKQVS 257
Query: 338 GFTAWFSVHFQSLQEGQPPQVLS 360
A S F+ L G+ VLS
Sbjct: 258 SSAACHSRRFEPLTSGRAQVVLS 280
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 48.9 bits (115), Expect = 9e-06
Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Query: 34 EFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDEYDP 93
+ + + DY A ++ +L+F +G+ I +L + DWW GE G G P+N+V K + DP
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYV-KLTTDMDP 1217
Query: 94 EDTW 97
W
Sbjct: 1218 SQQW 1221
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Query: 2 ATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILR 61
+TS D SES S A + V EEF+A+ Y ++++ L+F +G+ IL+ +
Sbjct: 976 STSMDSGSSESPASLKRVASPAA--KPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTK 1033
Query: 62 QTTADWWWGERAGCCGYIPANHV 84
+ DWW G G P+N+V
Sbjct: 1034 K-DGDWWTGTVGDKAGVFPSNYV 1055
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 5/61 (8%)
Query: 29 GVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGE-----RAGCCGYIPANH 83
G +PE IA Y AT QL+ G+ ILI ++ WW GE + G+ PAN+
Sbjct: 1073 GKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANY 1132
Query: 84 V 84
V
Sbjct: 1133 V 1133
Score = 35.0 bits (79), Expect = 0.13
Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
Query: 14 GEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERA 73
G P+ G EG+Q + A+ + A + L+F + + I +L Q WW+GE
Sbjct: 900 GSSPSPVLGQGEKVEGLQAQ---ALYPWRAKKDNHLNFNKNDVITVLEQQDM-WWFGEVQ 955
Query: 74 GCCGYIPANHV 84
G G+ P ++V
Sbjct: 956 GQKGWFPKSYV 966
>gi|15011979 Rho guanine nucleotide exchange factor 4 isoform a
[Homo sapiens]
Length = 690
Score = 47.4 bits (111), Expect = 3e-05
Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 4/100 (4%)
Query: 37 AIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDEYDPEDT 96
A+ D+ D+ +L F G+ I ++ T +WWWG A G+ PA+ V V++ +P D
Sbjct: 201 ALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPAD- 259
Query: 97 WQDEEYFGSYGTLK--LHLEMLADQPRTTKYHSVILQNKE 134
D G+ G + DQ RT + ++ ++
Sbjct: 260 -DDAPLAGNSGAEDGGAEAQSSKDQMRTNVINEILSTERD 298
>gi|15011981 Rho guanine nucleotide exchange factor 4 isoform b
[Homo sapiens]
Length = 670
Score = 47.4 bits (111), Expect = 3e-05
Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 4/100 (4%)
Query: 37 AIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDEYDPEDT 96
A+ D+ D+ +L F G+ I ++ T +WWWG A G+ PA+ V V++ +P D
Sbjct: 201 ALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPAD- 259
Query: 97 WQDEEYFGSYGTLK--LHLEMLADQPRTTKYHSVILQNKE 134
D G+ G + DQ RT + ++ ++
Sbjct: 260 -DDAPLAGNSGAEDGGAEAQSSKDQMRTNVINEILSTERD 298
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,356,140
Number of Sequences: 37866
Number of extensions: 770307
Number of successful extensions: 3026
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 158
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 2729
Number of HSP's gapped (non-prelim): 296
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.