BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|46249357 membrane-spanning 4-domains, subfamily A, member 7 isoform 1 [Homo sapiens] (240 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|11139299 membrane-spanning 4-domains, subfamily A, member 7 i... 478 e-135 gi|46249357 membrane-spanning 4-domains, subfamily A, member 7 i... 478 e-135 gi|46249347 membrane-spanning 4-domains, subfamily A, member 7 i... 365 e-101 gi|46249359 membrane-spanning 4-domains, subfamily A, member 7 i... 365 e-101 gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A ... 134 9e-32 gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A ... 133 2e-31 gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A ... 90 2e-18 gi|20070328 membrane-spanning 4-domains, subfamily A, member 4 i... 64 1e-10 gi|23110995 membrane-spanning 4-domains, subfamily A, member 4 i... 64 1e-10 gi|4503677 membrane-spanning 4-domains, subfamily A, member 2 is... 63 3e-10 gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A... 60 2e-09 gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A... 60 2e-09 gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A... 60 2e-09 gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i... 60 2e-09 gi|214831008 membrane-spanning 4-domains, subfamily A, member 2 ... 59 4e-09 gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [... 59 4e-09 gi|8923206 membrane-spanning 4-domains, subfamily A, member 12 [... 57 1e-08 gi|21264311 membrane-spanning 4-domains, subfamily A, member 6E ... 55 7e-08 gi|149588599 membrane-spanning 4-domains, subfamily A, member 15... 52 4e-07 gi|119226217 membrane-spanning 4-domains, subfamily A, member 14... 49 4e-06 gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B ... 48 9e-06 gi|169202868 PREDICTED: similar to membrane-spanning 4-domains, ... 47 1e-05 gi|169203526 PREDICTED: similar to membrane-spanning 4-domains, ... 47 1e-05 gi|169202217 PREDICTED: similar to membrane-spanning 4-domains, ... 47 1e-05 gi|23110987 membrane-spanning 4-domains, subfamily A, member 1 [... 42 4e-04 gi|23110989 membrane-spanning 4-domains, subfamily A, member 1 [... 42 4e-04 gi|119226220 membrane-spanning 4-domains, subfamily A, member 14... 41 0.001 gi|22749421 membrane-spanning 4-domains, subfamily A, member 15 ... 40 0.002 gi|167466260 membrane-spanning 4-domains, subfamily A, member 10... 39 0.004 gi|73486653 membrane-spanning 4-domains, subfamily A, member 3 i... 30 1.4 >gi|11139299 membrane-spanning 4-domains, subfamily A, member 7 isoform 1 [Homo sapiens] Length = 240 Score = 478 bits (1230), Expect = e-135 Identities = 240/240 (100%), Positives = 240/240 (100%) Query: 1 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLIS 60 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLIS Sbjct: 1 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLIS 60 Query: 61 SLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTS 120 SLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTS Sbjct: 61 SLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTS 120 Query: 121 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVS 180 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVS Sbjct: 121 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVS 180 Query: 181 LTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI 240 LTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI Sbjct: 181 LTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI 240 >gi|46249357 membrane-spanning 4-domains, subfamily A, member 7 isoform 1 [Homo sapiens] Length = 240 Score = 478 bits (1230), Expect = e-135 Identities = 240/240 (100%), Positives = 240/240 (100%) Query: 1 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLIS 60 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLIS Sbjct: 1 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLIS 60 Query: 61 SLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTS 120 SLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTS Sbjct: 61 SLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTS 120 Query: 121 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVS 180 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVS Sbjct: 121 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVS 180 Query: 181 LTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI 240 LTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI Sbjct: 181 LTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI 240 >gi|46249347 membrane-spanning 4-domains, subfamily A, member 7 isoform 2 [Homo sapiens] Length = 195 Score = 365 bits (938), Expect = e-101 Identities = 195/240 (81%), Positives = 195/240 (81%), Gaps = 45/240 (18%) Query: 1 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLIS 60 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLG Sbjct: 1 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLG----------- 49 Query: 61 SLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTS 120 FGITGSLSIISGKQSTKPFDLSSLTS Sbjct: 50 ----------------------------------FGITGSLSIISGKQSTKPFDLSSLTS 75 Query: 121 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVS 180 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVS Sbjct: 76 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVS 135 Query: 181 LTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI 240 LTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI Sbjct: 136 LTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI 195 >gi|46249359 membrane-spanning 4-domains, subfamily A, member 7 isoform 2 [Homo sapiens] Length = 195 Score = 365 bits (938), Expect = e-101 Identities = 195/240 (81%), Positives = 195/240 (81%), Gaps = 45/240 (18%) Query: 1 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLIS 60 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLG Sbjct: 1 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLG----------- 49 Query: 61 SLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTS 120 FGITGSLSIISGKQSTKPFDLSSLTS Sbjct: 50 ----------------------------------FGITGSLSIISGKQSTKPFDLSSLTS 75 Query: 121 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVS 180 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVS Sbjct: 76 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVS 135 Query: 181 LTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI 240 LTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI Sbjct: 136 LTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI 195 >gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A isoform 1 [Homo sapiens] Length = 248 Score = 134 bits (336), Expect = 9e-32 Identities = 80/201 (39%), Positives = 111/201 (55%), Gaps = 3/201 (1%) Query: 19 ITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPA 78 I Q EKP Q +D L+ L E V+GT+QILC +++ SLG IL A + +F Sbjct: 19 INFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQV 78 Query: 79 ISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADS 138 ST L S YPF+G F I+GSLSI + K+ TK SSL + +S+++A G +L+ Sbjct: 79 TSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVK 138 Query: 139 MVALRTASQHCGSEMDYLSSLPYSEYYY--PIYEIKDCLLTSVSLTGVLVVMLIFTVLEL 196 L AS C + + + + Y Y+Y +Y DC SL G L +MLI T+LE Sbjct: 139 QATLNPASLQCELDKNNIPTRSYVSYFYHDSLY-TTDCYTAKASLAGTLSLMLICTLLEF 197 Query: 197 LLAAYSSVFWWKQLYSNNPGS 217 LA ++V WKQ YS+ PGS Sbjct: 198 CLAVLTAVLRWKQAYSDFPGS 218 >gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A isoform 2 [Homo sapiens] Length = 225 Score = 133 bits (334), Expect = 2e-31 Identities = 80/202 (39%), Positives = 111/202 (54%), Gaps = 3/202 (1%) Query: 19 ITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPA 78 I Q EKP Q +D L+ L E V+GT+QILC +++ SLG IL A + +F Sbjct: 19 INFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQV 78 Query: 79 ISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADS 138 ST L S YPF+G F I+GSLSI + K+ TK SSL + +S+++A G +L+ Sbjct: 79 TSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVK 138 Query: 139 MVALRTASQHCGSEMDYLSSLPYSEYYY--PIYEIKDCLLTSVSLTGVLVVMLIFTVLEL 196 L AS C + + + + Y Y+Y +Y DC SL G L +MLI T+LE Sbjct: 139 QATLNPASLQCELDKNNIPTRSYVSYFYHDSLY-TTDCYTAKASLAGTLSLMLICTLLEF 197 Query: 197 LLAAYSSVFWWKQLYSNNPGSS 218 LA ++V WKQ YS+ PG S Sbjct: 198 CLAVLTAVLRWKQAYSDFPGVS 219 >gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A isoform 3 [Homo sapiens] Length = 178 Score = 90.1 bits (222), Expect = 2e-18 Identities = 54/136 (39%), Positives = 74/136 (54%) Query: 19 ITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPA 78 I Q EKP Q +D L+ L E V+GT+QILC +++ SLG IL A + +F Sbjct: 19 INFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQV 78 Query: 79 ISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADS 138 ST L S YPF+G F I+GSLSI + K+ TK SSL + +S+++A G +L+ Sbjct: 79 TSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVK 138 Query: 139 MVALRTASQHCGSEMD 154 L AS S D Sbjct: 139 QATLNPASLQWNSLSD 154 >gi|20070328 membrane-spanning 4-domains, subfamily A, member 4 isoform a [Homo sapiens] Length = 220 Score = 63.9 bits (154), Expect = 1e-10 Identities = 66/227 (29%), Positives = 98/227 (43%), Gaps = 27/227 (11%) Query: 9 GVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPT-----ETTVLGTVQILCCLLISSLG 63 G+ + G +PQ G+M +L GL E VLG VQIL L+ S+G Sbjct: 6 GMEQAMPGAGPGVPQL---GNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMG 62 Query: 64 AILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAV 123 ++ ++ + IS + GY G++ F I+GSLSI +G ++TK SL N Sbjct: 63 ITMMCMASNTYGSNPISVYI--GYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNIT 120 Query: 124 SSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTG 183 SSV A +G+ + S+ Y PY YY +C T L G Sbjct: 121 SSVLAASGILINTFSLAF-------------YSFHHPYCNYY---GNSNNCHGTMSILMG 164 Query: 184 VLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQ 230 + ++L+ +VLE +A S F K L PG S H+ + Sbjct: 165 LDGMVLLLSVLEFCIAVSLSAFGCKVLCC-TPGGVVLILPSHSHMAE 210 >gi|23110995 membrane-spanning 4-domains, subfamily A, member 4 isoform b [Homo sapiens] Length = 239 Score = 63.9 bits (154), Expect = 1e-10 Identities = 66/227 (29%), Positives = 98/227 (43%), Gaps = 27/227 (11%) Query: 9 GVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPT-----ETTVLGTVQILCCLLISSLG 63 G+ + G +PQ G+M +L GL E VLG VQIL L+ S+G Sbjct: 25 GMEQAMPGAGPGVPQL---GNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMG 81 Query: 64 AILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAV 123 ++ ++ + IS + GY G++ F I+GSLSI +G ++TK SL N Sbjct: 82 ITMMCMASNTYGSNPISVYI--GYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNIT 139 Query: 124 SSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTG 183 SSV A +G+ + S+ Y PY YY +C T L G Sbjct: 140 SSVLAASGILINTFSLAF-------------YSFHHPYCNYY---GNSNNCHGTMSILMG 183 Query: 184 VLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQ 230 + ++L+ +VLE +A S F K L PG S H+ + Sbjct: 184 LDGMVLLLSVLEFCIAVSLSAFGCKVLCC-TPGGVVLILPSHSHMAE 229 >gi|4503677 membrane-spanning 4-domains, subfamily A, member 2 isoform 1 [Homo sapiens] Length = 244 Score = 62.8 bits (151), Expect = 3e-10 Identities = 48/158 (30%), Positives = 73/158 (46%), Gaps = 20/158 (12%) Query: 41 LPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGS 100 L E LG QIL ++ G ++ SH I ++ +GYPF GA+ F I+G Sbjct: 54 LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113 Query: 101 LSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLP 160 LSIIS +++ SL +N SS+ G G+ +L ++ SL Sbjct: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITILI----------------INLKKSLA 157 Query: 161 YSEYY--YPIYEIKDCLLTSVSLTGVLVVMLIFTVLEL 196 Y + +E K C + S S T ++V+ML T+L L Sbjct: 158 YIHIHSCQKFFETK-CFMASFS-TEIVVMMLFLTILGL 193 >gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A, member 4E isoform 1 [Homo sapiens] Length = 243 Score = 60.1 bits (144), Expect = 2e-09 Identities = 56/203 (27%), Positives = 90/203 (44%), Gaps = 19/203 (9%) Query: 29 HMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYP 88 H Y + + + VLG V+IL L+ S+G I++ + S+ I + Y Sbjct: 51 HSYLCKGLQEKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYV--AYT 108 Query: 89 FLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQH 148 G++ F I+ SLS+ +G ++TK SL N SSV A +G+ + A S+ + Sbjct: 109 IWGSVMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTFYSFRYHY 168 Query: 149 CGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFWWK 208 C D LSS +C +T L G ++L+ +VLE +A S F K Sbjct: 169 CNH--DQLSS--------------NCYMTMSILMGTDGMVLLLSVLEFCIAVSLSAFGCK 212 Query: 209 QLYSNNPGSSFSSTQSQDHIQQV 231 L +P T S H+ ++ Sbjct: 213 VLCC-SPSEVVLITPSNSHMAEI 234 >gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A, member 4E isoform 3 [Homo sapiens] Length = 243 Score = 60.1 bits (144), Expect = 2e-09 Identities = 56/203 (27%), Positives = 90/203 (44%), Gaps = 19/203 (9%) Query: 29 HMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYP 88 H Y + + + VLG V+IL L+ S+G I++ + S+ I + Y Sbjct: 51 HSYLCKGLQEKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYV--AYT 108 Query: 89 FLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQH 148 G++ F I+ SLS+ +G ++TK SL N SSV A +G+ + A S+ + Sbjct: 109 IWGSVMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTFYSFRYHY 168 Query: 149 CGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFWWK 208 C D LSS +C +T L G ++L+ +VLE +A S F K Sbjct: 169 CNH--DQLSS--------------NCYMTMSILMGTDGMVLLLSVLEFCIAVSLSAFGCK 212 Query: 209 QLYSNNPGSSFSSTQSQDHIQQV 231 L +P T S H+ ++ Sbjct: 213 VLCC-SPSEVVLITPSNSHMAEI 234 >gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A, member 4E isoform 3 [Homo sapiens] Length = 243 Score = 60.1 bits (144), Expect = 2e-09 Identities = 56/203 (27%), Positives = 90/203 (44%), Gaps = 19/203 (9%) Query: 29 HMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYP 88 H Y + + + VLG V+IL L+ S+G I++ + S+ I + Y Sbjct: 51 HSYLCKGLQEKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYV--AYT 108 Query: 89 FLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQH 148 G++ F I+ SLS+ +G ++TK SL N SSV A +G+ + A S+ + Sbjct: 109 IWGSVMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTFYSFRYHY 168 Query: 149 CGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFWWK 208 C D LSS +C +T L G ++L+ +VLE +A S F K Sbjct: 169 CNH--DQLSS--------------NCYMTMSILMGTDGMVLLLSVLEFCIAVALSAFGCK 212 Query: 209 QLYSNNPGSSFSSTQSQDHIQQV 231 L +P T S H+ ++ Sbjct: 213 VLCC-SPSEVVLITPSNSHMAEI 234 >gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 isoform a [Homo sapiens] Length = 214 Score = 59.7 bits (143), Expect = 2e-09 Identities = 48/178 (26%), Positives = 81/178 (45%), Gaps = 16/178 (8%) Query: 30 MYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAIST-TLMSGYP 88 +YQ D + + VLG +QIL +I +LG L YP HF T +GYP Sbjct: 33 VYQPIDGSPDYQKAKLQVLGAIQILNAAMILALGVFLGSLQYPYHFQKHFFFFTFYTGYP 92 Query: 89 FLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQH 148 GA+ F +G+LS+++G + T+ + +S N S+ A G L+ ++ + + Sbjct: 93 IWGAVFFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQSLRS 152 Query: 149 CGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFW 206 C S + Y + S+S G++ ++LI T+LEL + + W Sbjct: 153 CHSSSESPDLCNY--------------MGSIS-NGMVSLLLILTLLELCVTISTIAMW 195 >gi|214831008 membrane-spanning 4-domains, subfamily A, member 2 isoform 2 [Homo sapiens] Length = 195 Score = 58.9 bits (141), Expect = 4e-09 Identities = 33/95 (34%), Positives = 49/95 (51%) Query: 41 LPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGS 100 L E LG QIL ++ G ++ SH I ++ +GYPF GA+ F I+G Sbjct: 54 LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113 Query: 101 LSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 135 LSIIS +++ SL +N SS+ G G+ +L Sbjct: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITIL 148 >gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [Homo sapiens] Length = 200 Score = 58.9 bits (141), Expect = 4e-09 Identities = 46/177 (25%), Positives = 85/177 (48%), Gaps = 26/177 (14%) Query: 31 YQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFA---PYPSHFNPAISTTLMSGY 87 + + LQ + +LGT+QIL ++ S G I +F PYP P I +SGY Sbjct: 33 FSTQSPLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRF--PFI---FLSGY 87 Query: 88 PFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQ 147 PF G++ F +G+ I +++T+ + S N +S++ A AG+ LL + Sbjct: 88 PFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFIL------ 141 Query: 148 HCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSV 204 + +Y+ YS ++ C +V G+L+ ++ F+++EL ++ S+ Sbjct: 142 ----DQNYICG--YS------HQNSQCKAVTVLFLGILITLMTFSIIELFISLPFSI 186 >gi|8923206 membrane-spanning 4-domains, subfamily A, member 12 [Homo sapiens] Length = 267 Score = 57.0 bits (136), Expect = 1e-08 Identities = 60/216 (27%), Positives = 91/216 (42%), Gaps = 44/216 (20%) Query: 3 LQSQTMGVSHSFTPKGITIP---QREKPGHMYQNEDYLQNGLPT-------ETTVLGTVQ 52 L++Q G + P GIT P +PG N + + T E LG +Q Sbjct: 39 LENQAQGAQRA-QPYGITSPGIFASSQPGQ--GNIQMINPSVGTAVMNFKEEAKALGVIQ 95 Query: 53 ILCCLLISSLGAILVFAPYPSHFNPAI---STTLMSGYPFLGALCFGITGSLSIISGKQS 109 I+ L+ G +L + F + ST ++ GYPF G L F I+GSLS+ + K+ Sbjct: 96 IMVGLMHIGFGIVLCLISFS--FREVLGFASTAVIGGYPFWGGLSFIISGSLSVSASKEL 153 Query: 110 TKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIY 169 ++ SL N VSS+ A G+ LL M A Q DY + L Sbjct: 154 SRCLVKGSLGMNIVSSILAFIGVILLLVDMCINGVAGQ------DYWAVL---------- 197 Query: 170 EIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVF 205 S G+ ++IF++LE +A ++ F Sbjct: 198 ----------SGKGISATLMIFSLLEFFVACATAHF 223 >gi|21264311 membrane-spanning 4-domains, subfamily A, member 6E [Homo sapiens] Length = 147 Score = 54.7 bits (130), Expect = 7e-08 Identities = 37/95 (38%), Positives = 51/95 (53%), Gaps = 2/95 (2%) Query: 116 SSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCG-SEMDYLSSLPYSEYYYPIYEIKDC 174 SSL + +S+++A G LL+ + AL AS C E D + L S Y+ Y + DC Sbjct: 52 SSLAGSILSALSALVGFILLSVNPAALNPASLQCKLDEKDIPTRLLLSYDYHSPYTM-DC 110 Query: 175 LLTSVSLTGVLVVMLIFTVLELLLAAYSSVFWWKQ 209 SL G L +ML+ TVLE LA ++V WKQ Sbjct: 111 HRAKASLAGTLSLMLVSTVLEFCLAVLTAVLQWKQ 145 Score = 31.2 bits (69), Expect = 0.84 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 3/63 (4%) Query: 19 ITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVF---APYPSHF 75 I Q EKP Q +D L+ L + V+G L ++S+L A++ F + P+ Sbjct: 19 INFSQAEKPEPTNQGQDSLKKRLQAKVKVIGVHSSLAGSILSALSALVGFILLSVNPAAL 78 Query: 76 NPA 78 NPA Sbjct: 79 NPA 81 >gi|149588599 membrane-spanning 4-domains, subfamily A, member 15 isoform 1 [Homo sapiens] Length = 240 Score = 52.4 bits (124), Expect = 4e-07 Identities = 41/120 (34%), Positives = 57/120 (47%), Gaps = 8/120 (6%) Query: 16 PKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHF 75 P G P+ +P + E +L E VLGTVQIL L+ G++L+ H Sbjct: 46 PLGAQTPRATQPPDLRPVETFLTG----EPKVLGTVQILIGLIHLGFGSVLLMVRR-GHV 100 Query: 76 NPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 135 + G PF G CF I+GSLS+ + K T SSL +N +S + A AG +L Sbjct: 101 GIFF---IEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAIL 157 >gi|119226217 membrane-spanning 4-domains, subfamily A, member 14 isoform 1 [Homo sapiens] Length = 679 Score = 48.9 bits (115), Expect = 4e-06 Identities = 36/119 (30%), Positives = 59/119 (49%), Gaps = 7/119 (5%) Query: 31 YQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFL 90 Y+ L + L E VLG QIL L+I G I FA F+ + +++GYPF Sbjct: 28 YRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTI--FALNYIGFSQRLPLVVLTGYPFW 85 Query: 91 GALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHC 149 GAL F +TG L++ K ++ + N +SS+ A G+ ++++ R ++C Sbjct: 86 GALIFILTGYLTVTDKKSKLLGQGVTGM--NVISSLVAITGITF---TILSYRHQDKYC 139 >gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B [Homo sapiens] Length = 250 Score = 47.8 bits (112), Expect = 9e-06 Identities = 48/173 (27%), Positives = 76/173 (43%), Gaps = 31/173 (17%) Query: 39 NGLPTETTV-----LGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFLGAL 93 NG P + + LG +QI+ L LG+I+ + +S + G+PF G L Sbjct: 58 NGQPVQKALKEGKTLGAIQIIIGLAHIGLGSIMATVLVGEY----LSISFYGGFPFWGGL 113 Query: 94 CFGITGSLSIISGKQSTKPFDLS-SLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSE 152 F I+GSLS+ + Q LS SL N VS++ + G+ L + Sbjct: 114 WFIISGSLSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDL------------- 160 Query: 153 MDYLSSLPYSEYYYPIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVF 205 S+P+ Y Y + ++++GVL L+F +LE +A SS F Sbjct: 161 -----SIPHPYAYPDYYPYAWGVNPGMAISGVL---LVFCLLEFGIACASSHF 205 >gi|169202868 PREDICTED: similar to membrane-spanning 4-domains, subfamily A, member 8B [Homo sapiens] Length = 391 Score = 47.0 bits (110), Expect = 1e-05 Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 13/120 (10%) Query: 19 ITIPQREKPGHMYQNEDYLQNGLPTETTVLGT-VQILCCL--LISSLGAILVFAPYPSHF 75 + + Q G Q Y Q P T L T +QIL L + S++ +L + P+ Sbjct: 120 LVVNQNSAAGVQSQPIGY-QRQYPVGTASLQTAIQILIGLTHIFSAINPVLYYYPF---- 174 Query: 76 NPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 135 T +SGYP G L + ++GSLS+ + K + SS++ N +S++ A AG+F++ Sbjct: 175 -----VTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFII 229 >gi|169203526 PREDICTED: similar to membrane-spanning 4-domains, subfamily A, member 8B [Homo sapiens] Length = 391 Score = 47.0 bits (110), Expect = 1e-05 Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 13/120 (10%) Query: 19 ITIPQREKPGHMYQNEDYLQNGLPTETTVLGT-VQILCCL--LISSLGAILVFAPYPSHF 75 + + Q G Q Y Q P T L T +QIL L + S++ +L + P+ Sbjct: 120 LVVNQNSAAGVQSQPIGY-QRQYPVGTASLQTAIQILIGLTHIFSAINPVLYYYPF---- 174 Query: 76 NPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 135 T +SGYP G L + ++GSLS+ + K + SS++ N +S++ A AG+F++ Sbjct: 175 -----VTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFII 229 >gi|169202217 PREDICTED: similar to membrane-spanning 4-domains, subfamily A, member 8B [Homo sapiens] Length = 391 Score = 47.0 bits (110), Expect = 1e-05 Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 13/120 (10%) Query: 19 ITIPQREKPGHMYQNEDYLQNGLPTETTVLGT-VQILCCL--LISSLGAILVFAPYPSHF 75 + + Q G Q Y Q P T L T +QIL L + S++ +L + P+ Sbjct: 120 LVVNQNSAAGVQSQPIGY-QRQYPVGTASLQTAIQILIGLTHIFSAINPVLYYYPF---- 174 Query: 76 NPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 135 T +SGYP G L + ++GSLS+ + K + SS++ N +S++ A AG+F++ Sbjct: 175 -----VTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFII 229 >gi|23110987 membrane-spanning 4-domains, subfamily A, member 1 [Homo sapiens] Length = 297 Score = 42.4 bits (98), Expect = 4e-04 Identities = 51/206 (24%), Positives = 85/206 (41%), Gaps = 34/206 (16%) Query: 44 ETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSI 103 E+ LG VQI+ L +LG +L+ P+ I T+ YP G + + I+GSL Sbjct: 48 ESKTLGAVQIMNGLFHIALGGLLMI---PAGIYAPICVTVW--YPLWGGIMYIISGSLLA 102 Query: 104 ISGKQSTKPFDLSSLTSNAVSSVTAGAGL--------------FLLADSMVALRTASQH- 148 + K S K + N++S A +G+ FL +S+ +R + + Sbjct: 103 ATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYI 162 Query: 149 ----CGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSV 204 C + P ++Y Y I + G+L VMLIF + L+ A Sbjct: 163 NIYNCEPANPSEKNSPSTQYCYSIQSL---------FLGILSVMLIFAFFQELVIAGIVE 213 Query: 205 FWWKQLYSNNPGSSFSSTQSQDHIQQ 230 WK+ S P S+ +++ +Q Sbjct: 214 NEWKRTCS-RPKSNIVLLSAEEKKEQ 238 >gi|23110989 membrane-spanning 4-domains, subfamily A, member 1 [Homo sapiens] Length = 297 Score = 42.4 bits (98), Expect = 4e-04 Identities = 51/206 (24%), Positives = 85/206 (41%), Gaps = 34/206 (16%) Query: 44 ETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSI 103 E+ LG VQI+ L +LG +L+ P+ I T+ YP G + + I+GSL Sbjct: 48 ESKTLGAVQIMNGLFHIALGGLLMI---PAGIYAPICVTVW--YPLWGGIMYIISGSLLA 102 Query: 104 ISGKQSTKPFDLSSLTSNAVSSVTAGAGL--------------FLLADSMVALRTASQH- 148 + K S K + N++S A +G+ FL +S+ +R + + Sbjct: 103 ATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYI 162 Query: 149 ----CGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSV 204 C + P ++Y Y I + G+L VMLIF + L+ A Sbjct: 163 NIYNCEPANPSEKNSPSTQYCYSIQSL---------FLGILSVMLIFAFFQELVIAGIVE 213 Query: 205 FWWKQLYSNNPGSSFSSTQSQDHIQQ 230 WK+ S P S+ +++ +Q Sbjct: 214 NEWKRTCS-RPKSNIVLLSAEEKKEQ 238 >gi|119226220 membrane-spanning 4-domains, subfamily A, member 14 isoform 2 [Homo sapiens] Length = 662 Score = 40.8 bits (94), Expect = 0.001 Identities = 42/148 (28%), Positives = 61/148 (41%), Gaps = 18/148 (12%) Query: 31 YQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFL 90 Y+ L + L E VLG QIL L+I G I FA F+ + +++GYPF Sbjct: 28 YRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTI--FALNYIGFSQRLPLVVLTGYPFW 85 Query: 91 GALC-FGITG-------------SLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLA 136 GAL G+TG + +I+S + K + S V S T LF L Sbjct: 86 GALIGQGVTGMNVISSLVAITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIVLFFLP 145 Query: 137 DSMVALRTASQHCGSEMDYLSSLPYSEY 164 + + + Q E D L + E+ Sbjct: 146 SDVT--QNSEQPAPEENDQLQFVLQEEF 171 >gi|22749421 membrane-spanning 4-domains, subfamily A, member 15 isoform 2 [Homo sapiens] Length = 147 Score = 39.7 bits (91), Expect = 0.002 Identities = 22/50 (44%), Positives = 29/50 (58%) Query: 86 GYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 135 G PF G CF I+GSLS+ + K T SSL +N +S + A AG +L Sbjct: 15 GVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAIL 64 >gi|167466260 membrane-spanning 4-domains, subfamily A, member 10 [Homo sapiens] Length = 267 Score = 38.9 bits (89), Expect = 0.004 Identities = 42/161 (26%), Positives = 65/161 (40%), Gaps = 26/161 (16%) Query: 48 LGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGK 107 LG I LL G L H L S YPF GA F I+G L+I Sbjct: 60 LGAFHITIALLHLVFGGYLASIVKNLHL-----VVLKSWYPFWGAASFLISGILAITMKT 114 Query: 108 QSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYP 167 S + L +N +S +GLF+++ + +L S P+ + Sbjct: 115 FSKTYLKMLCLMTNLISLFCVLSGLFVISKDL---------------FLES-PFESPIWR 158 Query: 168 IYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFWWK 208 +Y ++V + + + +L FTVLEL L ++V W+ Sbjct: 159 MYP-----NSTVHIQRLELALLCFTVLELFLPVPTAVTAWR 194 >gi|73486653 membrane-spanning 4-domains, subfamily A, member 3 isoform b [Homo sapiens] Length = 168 Score = 30.4 bits (67), Expect = 1.4 Identities = 27/117 (23%), Positives = 52/117 (44%), Gaps = 15/117 (12%) Query: 90 LGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHC 149 L L F +G+LS+++G + T+ + +S N S+ A G L+ ++ + + C Sbjct: 48 LQVLGFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQSLRSC 107 Query: 150 GSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFW 206 S + Y + S+S G++ ++LI T+LEL + + W Sbjct: 108 HSSSESPDLCNY--------------MGSIS-NGMVSLLLILTLLELCVTISTIAMW 149 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.132 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,368,822 Number of Sequences: 37866 Number of extensions: 332801 Number of successful extensions: 860 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 805 Number of HSP's gapped (non-prelim): 43 length of query: 240 length of database: 18,247,518 effective HSP length: 99 effective length of query: 141 effective length of database: 14,498,784 effective search space: 2044328544 effective search space used: 2044328544 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.