Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 131889097
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|131889097 cancer susceptibility candidate 1 isoform b [Homo
sapiens]
(716 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|131889097 cancer susceptibility candidate 1 isoform b [Homo s... 1424 0.0
gi|131888105 cancer susceptibility candidate 1 isoform a [Homo s... 1422 0.0
gi|131889447 cancer susceptibility candidate 1 isoform c [Homo s... 1241 0.0
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 55 3e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 54 4e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 52 2e-06
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 52 3e-06
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 51 3e-06
gi|56549694 enabled homolog isoform a [Homo sapiens] 50 7e-06
gi|39930375 enabled homolog isoform b [Homo sapiens] 50 7e-06
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 50 7e-06
gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo sap... 49 2e-05
gi|116174778 centrosome spindle pole associated protein 1 isofor... 48 3e-05
gi|116174789 centrosome spindle pole associated protein 1 isofor... 48 3e-05
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 48 4e-05
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 47 5e-05
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 47 5e-05
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 47 5e-05
gi|38044112 restin isoform b [Homo sapiens] 47 6e-05
gi|4506751 restin isoform a [Homo sapiens] 47 6e-05
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 47 6e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 47 6e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 47 6e-05
gi|154354979 myosin X [Homo sapiens] 47 8e-05
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 46 1e-04
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 46 1e-04
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 46 1e-04
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 46 1e-04
gi|92859701 myosin VI [Homo sapiens] 46 1e-04
gi|45439327 periplakin [Homo sapiens] 46 1e-04
>gi|131889097 cancer susceptibility candidate 1 isoform b [Homo
sapiens]
Length = 716
Score = 1424 bits (3685), Expect = 0.0
Identities = 716/716 (100%), Positives = 716/716 (100%)
Query: 1 MSGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAK 60
MSGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAK
Sbjct: 1 MSGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAK 60
Query: 61 DLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLW 120
DLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLW
Sbjct: 61 DLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLW 120
Query: 121 KEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKF 180
KEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKF
Sbjct: 121 KEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKF 180
Query: 181 GVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIP 240
GVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIP
Sbjct: 181 GVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIP 240
Query: 241 RILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEES 300
RILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEES
Sbjct: 241 RILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEES 300
Query: 301 KQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVE 360
KQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVE
Sbjct: 301 KQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVE 360
Query: 361 NSSEKPDFFEDNVVDLCQFTTLGGVYHLDILELPPQCKPVKGWMIVEILKEGLQKYTYPP 420
NSSEKPDFFEDNVVDLCQFTTLGGVYHLDILELPPQCKPVKGWMIVEILKEGLQKYTYPP
Sbjct: 361 NSSEKPDFFEDNVVDLCQFTTLGGVYHLDILELPPQCKPVKGWMIVEILKEGLQKYTYPP 420
Query: 421 ETTEEFETENAFPPIEVTLEVHENVIFFEDPVVVRWDAEGKHWRTDGISNVSYKPKERLV 480
ETTEEFETENAFPPIEVTLEVHENVIFFEDPVVVRWDAEGKHWRTDGISNVSYKPKERLV
Sbjct: 421 ETTEEFETENAFPPIEVTLEVHENVIFFEDPVVVRWDAEGKHWRTDGISNVSYKPKERLV 480
Query: 481 TFSLDTFGPVTLIQDAHINMPYQSWELRPLDVNKVLLTVTTVFTEIQIQIKENLCMLSSI 540
TFSLDTFGPVTLIQDAHINMPYQSWELRPLDVNKVLLTVTTVFTEIQIQIKENLCMLSSI
Sbjct: 481 TFSLDTFGPVTLIQDAHINMPYQSWELRPLDVNKVLLTVTTVFTEIQIQIKENLCMLSSI 540
Query: 541 KLKDKKHISILEGTWMTPIPFIIALKEAGLNIFPTRHSHFYVIINNKVPLVEVKAYRQMA 600
KLKDKKHISILEGTWMTPIPFIIALKEAGLNIFPTRHSHFYVIINNKVPLVEVKAYRQMA
Sbjct: 541 KLKDKKHISILEGTWMTPIPFIIALKEAGLNIFPTRHSHFYVIINNKVPLVEVKAYRQMA 600
Query: 601 LLSSAFAFGWSKWNLLCNSTKVVFKVREHLTEECTENPNWALLMFSGDRAQRLKIKEESE 660
LLSSAFAFGWSKWNLLCNSTKVVFKVREHLTEECTENPNWALLMFSGDRAQRLKIKEESE
Sbjct: 601 LLSSAFAFGWSKWNLLCNSTKVVFKVREHLTEECTENPNWALLMFSGDRAQRLKIKEESE 660
Query: 661 AFSEALKEETEFHSTLYHMVKDFASEEAMEKVRSSNCQFVNSVCHMLLSTRLLSYS 716
AFSEALKEETEFHSTLYHMVKDFASEEAMEKVRSSNCQFVNSVCHMLLSTRLLSYS
Sbjct: 661 AFSEALKEETEFHSTLYHMVKDFASEEAMEKVRSSNCQFVNSVCHMLLSTRLLSYS 716
>gi|131888105 cancer susceptibility candidate 1 isoform a [Homo
sapiens]
Length = 722
Score = 1422 bits (3680), Expect = 0.0
Identities = 715/715 (100%), Positives = 715/715 (100%)
Query: 2 SGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKD 61
SGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKD
Sbjct: 8 SGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKD 67
Query: 62 LERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWK 121
LERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWK
Sbjct: 68 LERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWK 127
Query: 122 EKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFG 181
EKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFG
Sbjct: 128 EKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFG 187
Query: 182 VATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPR 241
VATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPR
Sbjct: 188 VATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPR 247
Query: 242 ILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESK 301
ILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESK
Sbjct: 248 ILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESK 307
Query: 302 QQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVEN 361
QQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVEN
Sbjct: 308 QQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVEN 367
Query: 362 SSEKPDFFEDNVVDLCQFTTLGGVYHLDILELPPQCKPVKGWMIVEILKEGLQKYTYPPE 421
SSEKPDFFEDNVVDLCQFTTLGGVYHLDILELPPQCKPVKGWMIVEILKEGLQKYTYPPE
Sbjct: 368 SSEKPDFFEDNVVDLCQFTTLGGVYHLDILELPPQCKPVKGWMIVEILKEGLQKYTYPPE 427
Query: 422 TTEEFETENAFPPIEVTLEVHENVIFFEDPVVVRWDAEGKHWRTDGISNVSYKPKERLVT 481
TTEEFETENAFPPIEVTLEVHENVIFFEDPVVVRWDAEGKHWRTDGISNVSYKPKERLVT
Sbjct: 428 TTEEFETENAFPPIEVTLEVHENVIFFEDPVVVRWDAEGKHWRTDGISNVSYKPKERLVT 487
Query: 482 FSLDTFGPVTLIQDAHINMPYQSWELRPLDVNKVLLTVTTVFTEIQIQIKENLCMLSSIK 541
FSLDTFGPVTLIQDAHINMPYQSWELRPLDVNKVLLTVTTVFTEIQIQIKENLCMLSSIK
Sbjct: 488 FSLDTFGPVTLIQDAHINMPYQSWELRPLDVNKVLLTVTTVFTEIQIQIKENLCMLSSIK 547
Query: 542 LKDKKHISILEGTWMTPIPFIIALKEAGLNIFPTRHSHFYVIINNKVPLVEVKAYRQMAL 601
LKDKKHISILEGTWMTPIPFIIALKEAGLNIFPTRHSHFYVIINNKVPLVEVKAYRQMAL
Sbjct: 548 LKDKKHISILEGTWMTPIPFIIALKEAGLNIFPTRHSHFYVIINNKVPLVEVKAYRQMAL 607
Query: 602 LSSAFAFGWSKWNLLCNSTKVVFKVREHLTEECTENPNWALLMFSGDRAQRLKIKEESEA 661
LSSAFAFGWSKWNLLCNSTKVVFKVREHLTEECTENPNWALLMFSGDRAQRLKIKEESEA
Sbjct: 608 LSSAFAFGWSKWNLLCNSTKVVFKVREHLTEECTENPNWALLMFSGDRAQRLKIKEESEA 667
Query: 662 FSEALKEETEFHSTLYHMVKDFASEEAMEKVRSSNCQFVNSVCHMLLSTRLLSYS 716
FSEALKEETEFHSTLYHMVKDFASEEAMEKVRSSNCQFVNSVCHMLLSTRLLSYS
Sbjct: 668 FSEALKEETEFHSTLYHMVKDFASEEAMEKVRSSNCQFVNSVCHMLLSTRLLSYS 722
>gi|131889447 cancer susceptibility candidate 1 isoform c [Homo
sapiens]
Length = 690
Score = 1241 bits (3210), Expect = 0.0
Identities = 624/624 (100%), Positives = 624/624 (100%)
Query: 2 SGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKD 61
SGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKD
Sbjct: 66 SGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKD 125
Query: 62 LERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWK 121
LERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWK
Sbjct: 126 LERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWK 185
Query: 122 EKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFG 181
EKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFG
Sbjct: 186 EKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFG 245
Query: 182 VATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPR 241
VATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPR
Sbjct: 246 VATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPR 305
Query: 242 ILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESK 301
ILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESK
Sbjct: 306 ILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESK 365
Query: 302 QQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVEN 361
QQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVEN
Sbjct: 366 QQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVEN 425
Query: 362 SSEKPDFFEDNVVDLCQFTTLGGVYHLDILELPPQCKPVKGWMIVEILKEGLQKYTYPPE 421
SSEKPDFFEDNVVDLCQFTTLGGVYHLDILELPPQCKPVKGWMIVEILKEGLQKYTYPPE
Sbjct: 426 SSEKPDFFEDNVVDLCQFTTLGGVYHLDILELPPQCKPVKGWMIVEILKEGLQKYTYPPE 485
Query: 422 TTEEFETENAFPPIEVTLEVHENVIFFEDPVVVRWDAEGKHWRTDGISNVSYKPKERLVT 481
TTEEFETENAFPPIEVTLEVHENVIFFEDPVVVRWDAEGKHWRTDGISNVSYKPKERLVT
Sbjct: 486 TTEEFETENAFPPIEVTLEVHENVIFFEDPVVVRWDAEGKHWRTDGISNVSYKPKERLVT 545
Query: 482 FSLDTFGPVTLIQDAHINMPYQSWELRPLDVNKVLLTVTTVFTEIQIQIKENLCMLSSIK 541
FSLDTFGPVTLIQDAHINMPYQSWELRPLDVNKVLLTVTTVFTEIQIQIKENLCMLSSIK
Sbjct: 546 FSLDTFGPVTLIQDAHINMPYQSWELRPLDVNKVLLTVTTVFTEIQIQIKENLCMLSSIK 605
Query: 542 LKDKKHISILEGTWMTPIPFIIALKEAGLNIFPTRHSHFYVIINNKVPLVEVKAYRQMAL 601
LKDKKHISILEGTWMTPIPFIIALKEAGLNIFPTRHSHFYVIINNKVPLVEVKAYRQMAL
Sbjct: 606 LKDKKHISILEGTWMTPIPFIIALKEAGLNIFPTRHSHFYVIINNKVPLVEVKAYRQMAL 665
Query: 602 LSSAFAFGWSKWNLLCNSTKVVFK 625
LSSAFAFGWSKWNLLCNSTKVVFK
Sbjct: 666 LSSAFAFGWSKWNLLCNSTKVVFK 689
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 54.7 bits (130), Expect = 3e-07
Identities = 84/371 (22%), Positives = 160/371 (43%), Gaps = 45/371 (12%)
Query: 9 VTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRN-- 66
+T+ R LQ E E+ AR++ + + LE+Q +E ++ + K+LE
Sbjct: 1050 LTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQ 1109
Query: 67 ------------EELEELYL-LERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEM 113
ELEEL + L++ + +K QE +L+ + D M
Sbjct: 1110 KEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKK-----------DAQQTTLM 1158
Query: 114 NTFISLWKEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQ 173
N I+ ++ E +++ K+ + +L +++K ++ + + I Q S+ Q +
Sbjct: 1159 NMEIADYERLMKELNQKLTNKNNKIEDLEQEIK---IQKQKQETLQEEITSLQSSVQQYE 1215
Query: 174 ELLHLKFGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSET 233
E K ++L+K LAD + +I ++ + A+ ++ ++ T
Sbjct: 1216 E----KNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEIT 1271
Query: 234 QIGFEIPRILATS-DIAVRLLHTHYDHVSALHPVSTPSKEYTSAVT---ELVKDDVKNV- 288
+I L TS + R L + V+AL +K + VT E K V NV
Sbjct: 1272 SEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVL 1331
Query: 289 ----EKAISKEVEEESKQQ-ERGSHLIQEEEIKVEEEQGDIEVKMSSAE--EESEAIKCE 341
K++S+ E +KQ+ E LI + +IK+++ Q ++++ +S + + E
Sbjct: 1332 KQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLE 1391
Query: 342 REMKVLSETVS 352
R K+L ETVS
Sbjct: 1392 RHNKMLQETVS 1402
Score = 38.9 bits (89), Expect = 0.017
Identities = 98/448 (21%), Positives = 204/448 (45%), Gaps = 87/448 (19%)
Query: 1 MSGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYE--KEEMERLEIQRIEK------- 51
+S S+K+K+T ++ L+E+ E +E++EA L YE +E ME L+ + E
Sbjct: 445 LSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQE 504
Query: 52 -EKWHRLEAKDLERRNEELEELY-----LLE---RCFPEAEKLKQETKLLSQWKHYI--- 99
E + +A D+ ++L + LLE R E EKL + +L+ + ++ I
Sbjct: 505 FESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNL 564
Query: 100 -------------------QCDGSPDPSVAQEMNTFISLWKEKTNE--TFEEVIEK-SKV 137
+ +G + S+ +E + FI+ K E F + E+ ++
Sbjct: 565 QEKNGVYLLSLSQRDTMLKELEGKIN-SLTEEKDDFINKLKNSHEEMDNFHKKCEREERL 623
Query: 138 VLNLIEKLKFIL-----LETPPCDL----------QDKNIIQYQESILQLQELLHLKFGV 182
+L L +K++ + LE +L +D+N + ++ ++Q++ L K
Sbjct: 624 ILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDK--- 680
Query: 183 ATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRI 242
E+L + +L + ++ + K + L V+ + K++ ++ TQ+ ++ +
Sbjct: 681 --EVLSAEVKSLYE-ENNKLSSEKKQLSRDLEVFLSQKEDV---ILKEHITQLEKKLQLM 734
Query: 243 LATSDIAVRLLHTHYDHVSALHPVSTP----SKEYTSAVTELVKD-DVKNVEKAISKEVE 297
+ D +LL + V L V T KE S V+E ++ DV NV +A+ + +
Sbjct: 735 VEEQDNLNKLLEN--EQVQKLF-VKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLA 791
Query: 298 EESKQQ-----ERGSHLIQ-EEEIKVEEEQGDI---EVKMSSAEEESEAIKCEREMKVLS 348
+ ++++ +R +++ E+EIK +E+ + E+K + E E + +E++ +
Sbjct: 792 KINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQ 851
Query: 349 ETVSAAQ--LLLVENSSEKPDFFEDNVV 374
A Q LL ++N++EK N++
Sbjct: 852 SEKEALQSDLLEMKNANEKTRLENQNLL 879
Score = 33.1 bits (74), Expect = 0.92
Identities = 67/373 (17%), Positives = 163/373 (43%), Gaps = 44/373 (11%)
Query: 29 EEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEE---------LYLLERCF 79
E++A L+ + EE +++ E+ K+ ++++ EE+E+ LYL ++
Sbjct: 147 EDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLD 206
Query: 80 PEAEKLKQETKLLSQWKHYIQCDGSPDP----SVAQEMNTFISLWKEKTNETFEEVIEKS 135
++ K+ET ++Q ++ I+ + S+ +E+ ++ +E+ E ++ +
Sbjct: 207 ATTDE-KKET--VTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASA 263
Query: 136 K---VVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFGVATEILLKQAS 192
K +N + +LK L++ C+ +KNI + E EL +L+ + Q
Sbjct: 264 KEHEAEINKLNELKENLVKQ--CEASEKNIQKKYEC-----ELENLRKATSNANQDNQIC 316
Query: 193 TLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQI--GFEIPRILATSDIAV 250
++ ++ +E+V+ ++ ++ LK+ S+ E ++ + I
Sbjct: 317 SILLQENTFVEQVVNEK--VKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKD 374
Query: 251 RLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQERGSHLI 310
H D ++ + +KE V E +K ++ + K VE+ +++ +
Sbjct: 375 EFFHEREDLEFKINELLL-AKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQH 433
Query: 311 QEEEIKV--------EEEQGDIEVKMSSAEEESEAIKCEREMKVLS-----ETVSAAQLL 357
Q+E ++ E+E+ + ++ +E+ E ++ E++ +L+ E + Q
Sbjct: 434 QKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTE 493
Query: 358 LVENSSEKPDFFE 370
L E++ + FE
Sbjct: 494 LGESAGKISQEFE 506
Score = 33.1 bits (74), Expect = 0.92
Identities = 72/404 (17%), Positives = 163/404 (40%), Gaps = 35/404 (8%)
Query: 6 KKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERR 65
K K + L ++E EE+ E+E + K EK + ++++ ++ +K K+ +
Sbjct: 934 KSPSVKNDPLSSVKELEEKIENLEKECKEKEEK--INKIKLVAVKAKKELDSSRKETQTV 991
Query: 66 NEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVA--QEMNTFISLWKEK 123
EELE L ++ +L + + IQ S + ++ + + + KE+
Sbjct: 992 KEELESL------------RSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKER 1039
Query: 124 TNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFGVA 183
N FE IE +L +L+ L+ + +++++ E++ +LL ++
Sbjct: 1040 AN-NFEHRIE------DLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQI--- 1089
Query: 184 TEILLKQASTLADLDSGNMEK--VIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPR 241
E+ +A +L++ ++K IK+ T+ L+ + + +T E+ +
Sbjct: 1090 LEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVK 1149
Query: 242 ILATSDIAVRLLHTHYDH-VSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEV---E 297
A + + Y+ + L+ T + + +K K ++ + +E+ +
Sbjct: 1150 KDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQ-KQKQETLQEEITSLQ 1208
Query: 298 EESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLL 357
+Q E + I++ +K ++E D K + + + E++ + V ++
Sbjct: 1209 SSVQQYEEKNTKIKQLLVKTKKELAD--SKQAETDHLILQASLKGELEASQQQVEVYKIQ 1266
Query: 358 LVENSSEKPDFFEDNVVDLCQFTTLGGVYHLDILELPPQCKPVK 401
L E +SEK E Q Y + L +C+ K
Sbjct: 1267 LAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAK 1310
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 54.3 bits (129), Expect = 4e-07
Identities = 75/345 (21%), Positives = 149/345 (43%), Gaps = 40/345 (11%)
Query: 6 KKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEE-MERLEIQRIEKEKWHRLEAKDLER 64
+++ K R + + E+E +++ +EE + +EKEE M R E EKE+ R + + +
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEE--MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
Query: 65 RNEELEEL----YLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLW 120
+ E++ EL + E+ + EK ++E K+ Q K QE +
Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR-------------QEQEAKMWRQ 435
Query: 121 KEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKF 180
+EK E E++ E+ K + EK+ E ++K Q QE + + +E +H
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIH----EQEKIREEEKR--QEQEEMWRQEEKIH--- 486
Query: 181 GVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKK-NPRHRSVRFSETQIGFEI 239
E + +Q + + + EK+ K E VW +K + +R E ++ +
Sbjct: 487 --EQEEIWRQKEKMHEQE----EKIRKQEE---KVWRQEEKIREQEEKIREQEEKMWRQE 537
Query: 240 PRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEE 299
+I ++ H ++ E +++ + V + K E+E
Sbjct: 538 EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQE 597
Query: 300 SKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREM 344
K+QE+ + ++EE K+ E++ I+ + E+ E I+ + EM
Sbjct: 598 EKRQEQEEKMWKQEE-KIREQEEKIQEQEEKIREQEEKIREQEEM 641
Score = 49.3 bits (116), Expect = 1e-05
Identities = 79/374 (21%), Positives = 157/374 (41%), Gaps = 53/374 (14%)
Query: 1 MSGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRI-EKEKWHRLEA 59
M K++K+ + E + +EE+ R L+E+ + K ++E +R E ++I E+EK EA
Sbjct: 371 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 430
Query: 60 K----------DLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSV 109
K E+ E+ ++++ E E EK+++E K Q + + Q
Sbjct: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ--------- 481
Query: 110 AQEMNTFISLW--KEKTNETFEEVIEKSKVVLNLIEKLK---FILLETPPCDLQDKNIIQ 164
++++ +W KEK +E E++ ++ + V EK++ + E + + I+
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
Query: 165 YQESILQLQELLHLKFGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPR 224
QE + + +E +H + + E ++ D EK+ + E VW +K
Sbjct: 542 EQEEMWREEEKMHEQEKIWEE---EKRQEQEDKMWRQEEKIREQEE---KVWRQEEKIRE 595
Query: 225 HRSVRFSETQIGFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDD 284
R + + ++ + + + + +E E+ ++
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQE----------EKIQEQEEKIREQEEKIREQEEMTQEQ 645
Query: 285 VKNVEKAISKEVEEESKQQE------RGSHLIQEEEIKVEEEQGDI---EVKMSSAEE-- 333
+ + + K E+E K QE R I+E+E K+ E++ I E M EE
Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 705
Query: 334 -ESEAIKCEREMKV 346
E E CE+E K+
Sbjct: 706 WEQEEKMCEQEEKM 719
Score = 31.6 bits (70), Expect = 2.7
Identities = 22/94 (23%), Positives = 49/94 (52%), Gaps = 5/94 (5%)
Query: 6 KKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERR 65
+++ K + + +E+E ++ E+EE + E++ E+ E ++EK E K E+
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688
Query: 66 NEELEELYLL----ERCFPEAEKL-KQETKLLSQ 94
+ E+ ++ E+ + + EK+ +QE K+ Q
Sbjct: 689 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 722
Score = 31.2 bits (69), Expect = 3.5
Identities = 15/59 (25%), Positives = 38/59 (64%), Gaps = 2/59 (3%)
Query: 13 ERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEE 71
E+ +++QE+EE+ ++EE+ + EK + + +++R E++ W + L ++ E+++E
Sbjct: 693 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE--QEVRLRQQEEKMQE 749
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 52.0 bits (123), Expect = 2e-06
Identities = 78/357 (21%), Positives = 157/357 (43%), Gaps = 36/357 (10%)
Query: 5 KKKKVTKAERLKLLQEEE---ERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKD 61
++K++ + E+ QE+E ++ L+E+EE + E++ E+ E R ++EK R E +
Sbjct: 319 QEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 378
Query: 62 LERRNEELEELYLL----ERCFPEAEKLKQ-ETKLLSQWKHYIQCDGSPDPSVAQEMNTF 116
E+ + E+ + ER + + E+L++ E ++ Q K + Q + + QE
Sbjct: 379 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438
Query: 117 ISLWKEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELL 176
+EK E E + E+ K + E+ + + + Q++N+ + +E Q Q L
Sbjct: 439 TRDQEEKMQEE-ERIREREK---KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 494
Query: 177 HLKFGVATEILLKQASTLADLDS-GNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQI 235
K E L +Q + E+ I+D+ +W KK R +R E Q+
Sbjct: 495 EQK-----EKLWEQEKMQEQEEKIWEQEEKIRDQE---EMWGQEKKMWRQEKMREQEDQM 546
Query: 236 GFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKE 295
+ ++ +D + + ++ T E ++++ + E+ K+
Sbjct: 547 WEQEEKMRDQE-------QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER--EKK 597
Query: 296 VEEESKQQERGSHLIQEEEIKVEEEQGDI---EVKMSSAEE---ESEAIKCEREMKV 346
+ EE + +QE+E K++E++ + E KM EE E E E+E K+
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Score = 38.1 bits (87), Expect = 0.029
Identities = 24/90 (26%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
Query: 6 KKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAK-DLER 64
+++ + ER K ++EEEE ++EE+ + + EK + + E+ E++ W + E + +R
Sbjct: 710 REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR 769
Query: 65 RNEELEELYLLERCFPEAEKLKQETKLLSQ 94
E+ E+L+ E+ + + +QE K+ Q
Sbjct: 770 LPEQKEKLWEHEKMQEQEKIWEQEEKMRDQ 799
Score = 37.7 bits (86), Expect = 0.037
Identities = 25/97 (25%), Positives = 54/97 (55%), Gaps = 11/97 (11%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLER 64
+++K+ + ER++ E E++++EEEE + E++ E+ E + ++EK E K E+
Sbjct: 581 QEEKMREEERMR----EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ 636
Query: 65 RNEELEELYLLERCFPEAEKLKQETKLLSQ----WKH 97
+ E+ E+ + + EK+ ++ +L Q W+H
Sbjct: 637 EEKMWEQ---EEKMWEQEEKMWEQQRLPEQKEKLWEH 670
Score = 37.4 bits (85), Expect = 0.049
Identities = 38/172 (22%), Positives = 79/172 (45%), Gaps = 20/172 (11%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLER 64
++KK+ + E + E+E +++E+EE + E++ E+ E + ++EK E K E+
Sbjct: 594 REKKMREEEEM---MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 65 RNEELEELYLLER--CFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKE 122
+ E+ L E+ E EK++++ K+ Q + + + + QE T W +
Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT----WDQ 706
Query: 123 KTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQE 174
+ E + E+ K + E ++ + + +Q QE +Q QE
Sbjct: 707 EKMREEESMREREKKMREEEEMMR-----------EQEEKMQEQEEKMQEQE 747
Score = 35.8 bits (81), Expect = 0.14
Identities = 24/92 (26%), Positives = 51/92 (55%), Gaps = 5/92 (5%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEK-WHRLEAKDLE 63
++KK+ + E + E+E +++E+EE + E+E E+ E ++EK W + + +
Sbjct: 718 REKKMREEEEM---MREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774
Query: 64 RRNEELEELYLLERCFPEAEKLK-QETKLLSQ 94
+ E E++ E+ + + EK++ QE K+ Q
Sbjct: 775 EKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ 806
Score = 34.3 bits (77), Expect = 0.41
Identities = 26/99 (26%), Positives = 49/99 (49%), Gaps = 8/99 (8%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEM---ERLEIQRIEKEKWHRLEAKD 61
++KK E+++ + ER K EE + E+EE + ++Q E+E W +
Sbjct: 699 QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW-----EQ 753
Query: 62 LERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQ 100
E+ E+ E+++ +R + EKL + K+ Q K + Q
Sbjct: 754 EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQ 792
Score = 33.9 bits (76), Expect = 0.54
Identities = 33/146 (22%), Positives = 69/146 (47%), Gaps = 15/146 (10%)
Query: 13 ERLKLLQEEEERRLKEEEEARLKYEK----------EEMERLEIQRIEKEK---WHRLEA 59
E+ + +QE+EE+ ++EE+ + + EK +E + E QR+ ++K W +
Sbjct: 614 EQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 673
Query: 60 KDLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISL 119
++ E+ E+ E+++ E+ E + +QE K Q K + +E +
Sbjct: 674 QEQEKMQEQEEKIWEQEKM--EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMRE 731
Query: 120 WKEKTNETFEEVIEKSKVVLNLIEKL 145
+EK E E++ E+ + + EK+
Sbjct: 732 QEEKMQEQEEKMQEQEEEMWEQEEKM 757
Score = 32.7 bits (73), Expect = 1.2
Identities = 33/145 (22%), Positives = 70/145 (48%), Gaps = 20/145 (13%)
Query: 5 KKKKVTKAERLKLLQEE---EERRLKEEEEARLKYEKEEMERLEIQRIEKEK-WHRLEAK 60
+++K+ + E QEE E++RL E++E +E E+M+ E + ++EK W E +
Sbjct: 636 QEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL--WEHEKMQEQEKMQEQEEKIW---EQE 690
Query: 61 DLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLW 120
+E++ +E E+ + E E +++ K + + + + +E +
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMRE-----------EEEMMREQEEKMQEQ 739
Query: 121 KEKTNETFEEVIEKSKVVLNLIEKL 145
+EK E EE+ E+ + + EK+
Sbjct: 740 EEKMQEQEEEMWEQEEKMWEQEEKM 764
Score = 31.6 bits (70), Expect = 2.7
Identities = 24/108 (22%), Positives = 60/108 (55%), Gaps = 24/108 (22%)
Query: 5 KKKKVTKAERLKLLQEEEERR------LKEEEEARLKYEK----EEMERLEIQRIEKEKW 54
+++K+ + E+++ +E+E++ ++EEE R + +K EEM R + +++++++
Sbjct: 682 QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE- 740
Query: 55 HRLEAKDLERRNEELEELY-LLERCFPEAEKLKQETKLLSQ----WKH 97
E+ E+ EE++ E+ + + EK+ ++ +L Q W+H
Sbjct: 741 --------EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH 780
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 51.6 bits (122), Expect = 3e-06
Identities = 37/96 (38%), Positives = 53/96 (55%), Gaps = 6/96 (6%)
Query: 5 KKKKVTKA------ERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLE 58
KKK +KA E L L+EEEER+ +EEEE + E+ E +R E +R+E+EK R +
Sbjct: 332 KKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKK 391
Query: 59 AKDLERRNEELEELYLLERCFPEAEKLKQETKLLSQ 94
K+ ER+ +E LL + EA + T L Q
Sbjct: 392 QKEKERKERLKKEGKLLTKSQREARARAEATLKLLQ 427
Score = 44.7 bits (104), Expect = 3e-04
Identities = 30/90 (33%), Positives = 52/90 (57%), Gaps = 10/90 (11%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLER 64
+KKK +K +QE + LKEEEE + + E+E ++RLE ++++ RLE + ER
Sbjct: 331 EKKKGPSKATVKAMQEALAK-LKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRER 389
Query: 65 RNEELEELYLLERCFPEAEKLKQETKLLSQ 94
+ ++ +E E+LK+E KLL++
Sbjct: 390 KKQKEKE---------RKERLKKEGKLLTK 410
Score = 41.6 bits (96), Expect = 0.003
Identities = 78/367 (21%), Positives = 149/367 (40%), Gaps = 47/367 (12%)
Query: 8 KVTKAERLKLLQEEEERRLKEEEEARLKY--EKEEMER-LEIQRIEKEKWHRLEAKDLER 64
K+ + K ++E ER+ ++EE+A+L+ EKEE+E + Q +KE + E + ++
Sbjct: 224 KIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKS 283
Query: 65 R----------NEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVA--QE 112
+ +EE E E +K K++ K K + + PS A +
Sbjct: 284 KVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKA 343
Query: 113 MNTFISLWKEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQL 172
M ++ KE+ E E+ K + L K K E + +++ + +E +L
Sbjct: 344 MQEALAKLKEEEERQKREEEERIKRLEELEAKRKEE--ERLEQEKRERKKQKEKERKERL 401
Query: 173 QELLHLKFGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSE 232
++ L E + +TL L + +E KD KK P + + +
Sbjct: 402 KKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLP--------KKRPIYEDKKRKK 453
Query: 233 TQIGFEIPRILATSDI--AVRLLHTHYDHVSALHPVSTPSKEY--------------TSA 276
E + + ++ AV ++ P P +E +
Sbjct: 454 IPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDE 513
Query: 277 VTELVKDDVKNVEKAISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESE 336
TE V+ + ++E + E EEE +++E +E+E EEE+ + E + S +EE E
Sbjct: 514 ETEKVEGNKVHIEVKENPEEEEEEEEEE------EEDEESEEEEEEEGESEGSEGDEEDE 567
Query: 337 AIKCERE 343
+ E++
Sbjct: 568 KVSDEKD 574
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 51.2 bits (121), Expect = 3e-06
Identities = 83/358 (23%), Positives = 144/358 (40%), Gaps = 44/358 (12%)
Query: 20 EEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELYLLE--R 77
E E RL+ EE R+K E+++ E RIE E+ + A++ ERR E E E R
Sbjct: 266 EAERARLEAEERERIKAEQDKKIADERARIEAEE--KAAAQERERREAEERERMREEEKR 323
Query: 78 CFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNETFEEVIEKSKV 137
E +++K+E K ++ + I+ + Q + E+ E EK+KV
Sbjct: 324 AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKV 383
Query: 138 V----LNLIEKLKFILLETP------PCDLQDK--NIIQYQESILQLQELLHLKFGVATE 185
+E+ K + ET ++ K N + QE LQ L T+
Sbjct: 384 EEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTK 443
Query: 186 ILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRILAT 245
+ K+ D + E+ IKDE + K P+ F + + GF +
Sbjct: 444 VQAKREKLQEDKPTFKKEE-IKDEKI------KKDKEPKEEVKSFMDRKKGFTEVKSQNG 496
Query: 246 SDIAVRLLHTHYD--------HVSALHPVSTPSKEYTSAVTELVK----------DDVKN 287
+ +L HT V P E + EL + + +K
Sbjct: 497 EFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQ 556
Query: 288 VEKAISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMK 345
++ + E+EE K++E +++EEE + ++E+ D +++ EEE +K E E +
Sbjct: 557 KQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLR---EEEEKRRLKEEIERR 611
Score = 39.7 bits (91), Expect = 0.010
Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 12/88 (13%)
Query: 8 KVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNE 67
K + ER K+L+EEE+RR +EE + +L+ E+EE RL KE+ R A+ E+R +
Sbjct: 569 KKKREERRKVLEEEEQRRKQEEADRKLR-EEEEKRRL------KEEIERRRAEAAEKRQK 621
Query: 68 ELEELYLLE----RCF-PEAEKLKQETK 90
E+ + +CF P+ LK E +
Sbjct: 622 MPEDGLSDDKKPFKCFTPKGSSLKIEER 649
Score = 37.0 bits (84), Expect = 0.064
Identities = 20/49 (40%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEK 53
+++KV + E + QEE +R+L+EEEE R KEE+ER + EK +
Sbjct: 574 ERRKVLEEEEQRRKQEEADRKLREEEEKRRL--KEEIERRRAEAAEKRQ 620
Score = 36.2 bits (82), Expect = 0.11
Identities = 25/77 (32%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Query: 274 TSAVTELVKDDVKNVEKAISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAE- 332
T + E V +KN + IS E ++ +++E+GS I E EE++ E + + E
Sbjct: 217 TESQEETVVMSLKNGQ--ISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEA 274
Query: 333 EESEAIKCEREMKVLSE 349
EE E IK E++ K+ E
Sbjct: 275 EERERIKAEQDKKIADE 291
Score = 35.8 bits (81), Expect = 0.14
Identities = 70/333 (21%), Positives = 139/333 (41%), Gaps = 48/333 (14%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLER 64
+K+ + +R+K EEE+R EE + + EK E + R E+E+ ++E ++
Sbjct: 335 EKRAAEERQRIK----EEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEE---QK 387
Query: 65 RNEELEE-LYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEK 123
RN++LEE + ++ + EK++Q K+ +W + AQE ++ K++
Sbjct: 388 RNKQLEEKKHAMQETKIKGEKVEQ--KIEGKW---------VNEKKAQEDKLQTAVLKKQ 436
Query: 124 TNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFGVA 183
E +V K EKL+ +++D+ I + +E +++ + K G
Sbjct: 437 GEEKGTKVQAKR-------EKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGF- 488
Query: 184 TEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRIL 243
TE+ + + K+ EN + SV E + ++
Sbjct: 489 TEVKSQNGEFMT-------HKLKHTEN-------TFSRPGGRASVDTKEAEGAPQVEAGK 534
Query: 244 ATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQ 303
++ R T + L ++ A EL + K E+ E EE+ ++Q
Sbjct: 535 RLEELRRRRGETESEEFEKL------KQKQQEAALELEELKKKREERRKVLEEEEQRRKQ 588
Query: 304 ERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESE 336
E ++EEE K ++ +IE + + A E+ +
Sbjct: 589 EEADRKLREEEEKRRLKE-EIERRRAEAAEKRQ 620
Score = 34.7 bits (78), Expect = 0.32
Identities = 70/350 (20%), Positives = 134/350 (38%), Gaps = 51/350 (14%)
Query: 29 EEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELYLLE---RCFPEAEKL 85
E L+ +K E RLE +RI + RN++ EE E R E +
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQ------------RNDDDEEEAARERRRRARQERLRQ 52
Query: 86 KQETKLLSQWKHYIQCDGS---PDPSV-AQEMNTFI------------SLWKEKTNETFE 129
KQE + L Q ++ + PD NT + + +E+ + +
Sbjct: 53 KQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQ 112
Query: 130 EVIEKSKVVLNLIEKLKFIL-LETPPCDLQDKNIIQYQESILQLQELLHLKFGVATEILL 188
E +E+ K I L D + + +E QE ++ TE +
Sbjct: 113 EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIE---ETETVT 169
Query: 189 K--QASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRILATS 246
K Q + D + E K+E ++ P+ S+ E Q+ + S
Sbjct: 170 KSYQKNDWRDAEENKKEDKEKEEEE--------EEKPKRGSI--GENQVEVMVEEKTTES 219
Query: 247 DIAVRLLHTHYDHVSALHPVSTPSKEYTS-AVTELVKDDVKNVEKAISKEVEEESKQQER 305
++ +S+ P +E S ++ K + ++ E+A ++ E++++ER
Sbjct: 220 QEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERER 279
Query: 306 GSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQ 355
+ E++ K+ +E+ IE + +A +E E + E ++ E AA+
Sbjct: 280 ---IKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAE 326
Score = 32.0 bits (71), Expect = 2.1
Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 282 KDDVKNVEKAISKE---VEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAI 338
++ ++ EK ++E ++EE K+ I+EEE + EE+ I+ + A EE +
Sbjct: 314 RERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRA 373
Query: 339 KCEREMKVLSE 349
+ E E K E
Sbjct: 374 RAEEEEKAKVE 384
Score = 30.0 bits (66), Expect = 7.8
Identities = 21/78 (26%), Positives = 34/78 (43%)
Query: 279 ELVKDDVKNVEKAISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAI 338
E ++++ K + + EEE + E + +EE+ EE Q E + +AEE A
Sbjct: 315 ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRAR 374
Query: 339 KCEREMKVLSETVSAAQL 356
E E + E QL
Sbjct: 375 AEEEEKAKVEEQKRNKQL 392
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 50.1 bits (118), Expect = 7e-06
Identities = 32/78 (41%), Positives = 48/78 (61%), Gaps = 6/78 (7%)
Query: 19 QEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKW--HRLEAKDLERRNEELEELYLLE 76
Q +E++R KE E RL+ E+ E ERLE +R+E+E+ RLE + LER +E E LE
Sbjct: 146 QLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLE 205
Query: 77 RCFPEAEKLKQETKLLSQ 94
R E+L+++ +L Q
Sbjct: 206 R----QERLERQERLERQ 219
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/88 (34%), Positives = 51/88 (57%), Gaps = 1/88 (1%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEE-EEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLE 63
+++K + ERL+ + E ER +E E RL+ E+ E E+LE +R E+E+ RLE ++
Sbjct: 151 QRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERL 210
Query: 64 RRNEELEELYLLERCFPEAEKLKQETKL 91
R E LE L+R E ++ ++ +L
Sbjct: 211 ERQERLERQERLDRERQERQERERLERL 238
Score = 45.1 bits (105), Expect = 2e-04
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 5/112 (4%)
Query: 11 KAERLKLLQEEEER-RLKEEEEARLKYEKEEMERLEIQ-RIEK-EKWHRLEAKDLERR-N 66
+ ER +L +E ER RL++E+ R + E+E ERLE Q R+E+ E+ R E D ER+
Sbjct: 170 RLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQER 229
Query: 67 EELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDP-SVAQEMNTFI 117
+E E L LER E E+ +Q + +W+ + + P SV +N+ +
Sbjct: 230 QERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVL 281
Score = 40.8 bits (94), Expect = 0.004
Identities = 33/119 (27%), Positives = 62/119 (52%), Gaps = 4/119 (3%)
Query: 20 EEEERRLKEEEEAR-LKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELYLLERC 78
E + R+L+E++ + L+ E+ E ER+E +R+E+E RLE + LER E E+L +
Sbjct: 141 EIQRRQLQEQQRQKELERERLERERMERERLERE---RLERERLERERLEQEQLERERQE 197
Query: 79 FPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNETFEEVIEKSKV 137
E+L+++ +L Q + Q + QE L +E+ +E +E+ ++
Sbjct: 198 RERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQL 256
Score = 40.8 bits (94), Expect = 0.004
Identities = 22/63 (34%), Positives = 41/63 (65%), Gaps = 1/63 (1%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLER 64
+++++ + ERL+ QE ER+ + + E + + E+E +ERLE +R E+E+ +LE + LE
Sbjct: 200 RQERLERQERLER-QERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEW 258
Query: 65 RNE 67
E
Sbjct: 259 ERE 261
Score = 32.7 bits (73), Expect = 1.2
Identities = 15/55 (27%), Positives = 34/55 (61%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEA 59
+++++ + ERL ++E + R + E R + E+E E+LE +++E E+ R+ +
Sbjct: 212 RQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISS 266
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 50.1 bits (118), Expect = 7e-06
Identities = 32/78 (41%), Positives = 48/78 (61%), Gaps = 6/78 (7%)
Query: 19 QEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKW--HRLEAKDLERRNEELEELYLLE 76
Q +E++R KE E RL+ E+ E ERLE +R+E+E+ RLE + LER +E E LE
Sbjct: 146 QLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLE 205
Query: 77 RCFPEAEKLKQETKLLSQ 94
R E+L+++ +L Q
Sbjct: 206 R----QERLERQERLERQ 219
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/88 (34%), Positives = 51/88 (57%), Gaps = 1/88 (1%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEE-EEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLE 63
+++K + ERL+ + E ER +E E RL+ E+ E E+LE +R E+E+ RLE ++
Sbjct: 151 QRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERL 210
Query: 64 RRNEELEELYLLERCFPEAEKLKQETKL 91
R E LE L+R E ++ ++ +L
Sbjct: 211 ERQERLERQERLDRERQERQERERLERL 238
Score = 45.1 bits (105), Expect = 2e-04
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 5/112 (4%)
Query: 11 KAERLKLLQEEEER-RLKEEEEARLKYEKEEMERLEIQ-RIEK-EKWHRLEAKDLERR-N 66
+ ER +L +E ER RL++E+ R + E+E ERLE Q R+E+ E+ R E D ER+
Sbjct: 170 RLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQER 229
Query: 67 EELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDP-SVAQEMNTFI 117
+E E L LER E E+ +Q + +W+ + + P SV +N+ +
Sbjct: 230 QERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVL 281
Score = 40.8 bits (94), Expect = 0.004
Identities = 33/119 (27%), Positives = 62/119 (52%), Gaps = 4/119 (3%)
Query: 20 EEEERRLKEEEEAR-LKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELYLLERC 78
E + R+L+E++ + L+ E+ E ER+E +R+E+E RLE + LER E E+L +
Sbjct: 141 EIQRRQLQEQQRQKELERERLERERMERERLERE---RLERERLERERLEQEQLERERQE 197
Query: 79 FPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNETFEEVIEKSKV 137
E+L+++ +L Q + Q + QE L +E+ +E +E+ ++
Sbjct: 198 RERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQL 256
Score = 40.8 bits (94), Expect = 0.004
Identities = 22/63 (34%), Positives = 41/63 (65%), Gaps = 1/63 (1%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLER 64
+++++ + ERL+ QE ER+ + + E + + E+E +ERLE +R E+E+ +LE + LE
Sbjct: 200 RQERLERQERLER-QERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEW 258
Query: 65 RNE 67
E
Sbjct: 259 ERE 261
Score = 32.7 bits (73), Expect = 1.2
Identities = 15/55 (27%), Positives = 34/55 (61%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEA 59
+++++ + ERL ++E + R + E R + E+E E+LE +++E E+ R+ +
Sbjct: 212 RQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISS 266
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain
1 [Homo sapiens]
Length = 1412
Score = 50.1 bits (118), Expect = 7e-06
Identities = 84/388 (21%), Positives = 168/388 (43%), Gaps = 42/388 (10%)
Query: 7 KKVTKAE-RLKLLQEEEERRLKEEEEARLKYEKEEME-------RLEIQRIEKEKW---- 54
K +T+ + R+K EEE+ R++E EE RL +KE +E R + +E EK
Sbjct: 728 KSITQEKNRVKEALEEEQTRVQELEE-RLARQKEVLESSIAHEKRKAKEALESEKRKVQD 786
Query: 55 ---HRLEAKDLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQ 111
H + K++ N E+ E E +K++ L++ K ++ + +
Sbjct: 787 LENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQKEELELKEQKEDVLNN 846
Query: 112 EMNTFISLWKEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQ 171
+++ +++ +E E ++ + L L E L + + ++ +I Q+ +
Sbjct: 847 KLSDALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMIMVEERLILQQKMVKA 906
Query: 172 LQ-ELLHLKFGVATEIL-----LKQ-ASTLADLDSGNMEKVIKDENVTLYVWANLKKN-P 223
LQ E + G EI+ +KQ A T+ L+ ++KV + A LK N P
Sbjct: 907 LQDEQESQRHGFEEEIMEYKEQIKQHAQTIVSLEE-KLQKVTQHHKKIEGEIATLKDNDP 965
Query: 224 RHRSVRFSETQIGFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKD 283
+ R + P + ++ + + Y+H+ + + KE S E++
Sbjct: 966 APKEERPQD-------PLVAPMTESSAK--DMAYEHL--IDDLLAAQKEILSQ-QEVIMK 1013
Query: 284 DVKNVEKAISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEV-KMSSAEEESEAIKCER 342
K++ +A S+ + + E+ +++ + V+++ ++ V K A+ S K +R
Sbjct: 1014 LRKDLTEAHSRMSDLRGELNEKQKMELEQNVVLVQQQSKELSVLKEKMAQMSSLVEKKDR 1073
Query: 343 EMKVLSETVSAAQ----LLLVENSSEKP 366
E+K L E + A+Q L L +KP
Sbjct: 1074 ELKALEEALRASQEKHRLQLNTEKEQKP 1101
Score = 37.7 bits (86), Expect = 0.037
Identities = 100/416 (24%), Positives = 161/416 (38%), Gaps = 75/416 (18%)
Query: 6 KKKVTKAE-RLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLER 64
+K +T+A R+ L+ E + K E E + +++ + L + KEK ++ + +E+
Sbjct: 1015 RKDLTEAHSRMSDLRGELNEKQKMELEQNVVLVQQQSKELSVL---KEKMAQMSSL-VEK 1070
Query: 65 RNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQ-CDGSP--DP------SVAQEMNT 115
++ EL+ L R E +L+ T+ + + Q CD S +P S +QE +
Sbjct: 1071 KDRELKALEEALRASQEKHRLQLNTEKEQKPRKKTQTCDTSVQIEPVHTEAFSSSQEQQS 1130
Query: 116 FISLWKEKTNETFEEVIEKSKVVLN-LIEKLKFILLETPPCDLQDKNIIQYQESILQLQE 174
F L EEVI++ K L+ L ++K + P +N ES L L+
Sbjct: 1131 FSDLGVRCKGSRHEEVIQRQKKALSELRARIKELEKARSPDHKDHQN-----ESFLDLKN 1185
Query: 175 ----------LLHLKFGVAT----EILLKQASTL------ADLDSGNM---------EKV 205
LL K + T EIL Q A SG M EK+
Sbjct: 1186 LRMENNVQKILLDAKPDLPTLSRIEILAPQNGLCNARFGSAMEKSGKMDVAEALELSEKL 1245
Query: 206 IKDENVTLYVWANLKKNPRHRSVRFSETQ---------------IGFEIPRILATSDIAV 250
D + TL N+K H S+++ Q + +I ++
Sbjct: 1246 YLDMSKTLGSLMNIKNMSGHVSMKYLSRQEREKVNQLRQRDLDLVFDKITQLKNQLGRKE 1305
Query: 251 RLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNV-EKAISKEVEEESKQQERGSHL 309
LL + V L + Y S V +L D K EKA+ KE E + Q L
Sbjct: 1306 ELLRGYEKDVEQLRRSKVSIEMYQSQVAKLEDDIYKEAEEKALLKEALERMEHQ-----L 1360
Query: 310 IQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVENSSEK 365
QE+ I Q + + +S + + EREM + ++Q LL S K
Sbjct: 1361 CQEKRINRAIRQQKVGTRKASLKMDQ-----EREMLRKETSSKSSQSLLHSKPSGK 1411
>gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo
sapiens]
Length = 619
Score = 48.9 bits (115), Expect = 2e-05
Identities = 44/181 (24%), Positives = 85/181 (46%), Gaps = 17/181 (9%)
Query: 13 ERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEEL 72
E L+L + +E EEEE K +EE E E + + + H +A L +E
Sbjct: 251 ELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEE-DLQCAHPCDAPKLIS-----QEA 304
Query: 73 YLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNETFEEVI 132
L + P+ E L+++ +LL + H ++ + S ++ E I E+ +E +++
Sbjct: 305 LLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEASQQMA 364
Query: 133 EKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFGVATEILLKQAS 192
E S+V++ +E + Q + + + Q +L+LQ+ + +G TE L KQ +
Sbjct: 365 ELSEVLVLRLENY----------ERQQQEVARLQAQVLKLQQRCRM-YGAETEKLQKQLA 413
Query: 193 T 193
+
Sbjct: 414 S 414
>gi|116174778 centrosome spindle pole associated protein 1 isoform b
[Homo sapiens]
Length = 1221
Score = 48.1 bits (113), Expect = 3e-05
Identities = 51/191 (26%), Positives = 92/191 (48%), Gaps = 25/191 (13%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEE-----MERLEIQRIEKEKWHRL-- 57
K+++ + ERL++ +E+EERRL E+ AR++ E EE E+ E QR++ E+ RL
Sbjct: 747 KQREEAERERLRIAEEKEERRL-AEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE 805
Query: 58 -EAKDLERRNEELEELYLLE---------RCFPEAEKLKQETKLLSQWKHYIQCDGSPDP 107
K+ ER+ +E EE Y L+ E + ++Q + ++ ++ I P
Sbjct: 806 ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 865
Query: 108 SVAQEMNTFISLWKEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQE 167
SV + +FI + + + K L E+ K +++E Q ++ +E
Sbjct: 866 SVDSIIRSFIH--ESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQ----LRSEE 919
Query: 168 SILQLQELLHL 178
LQ + LLH+
Sbjct: 920 RRLQ-ERLLHM 929
Score = 40.8 bits (94), Expect = 0.004
Identities = 39/171 (22%), Positives = 78/171 (45%), Gaps = 15/171 (8%)
Query: 19 QEEEERRLKEEEEARLKYEKEEME------RLEIQRIEKEKWHRLEAKDLERRNEELEEL 72
Q EE+++ +E E RL+ +E+ E R IQ+ +E+ + K+ E+R + E +
Sbjct: 742 QIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHI 801
Query: 73 YLLERCFPEAEKLK--QETKLLSQWKHYIQCDG--SPDPSVAQEMNTFISLWKEKTNETF 128
L E EAE+ K +E K Q +HY + D + ++ + + + K
Sbjct: 802 RLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKL 861
Query: 129 EEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQES----ILQLQEL 175
+ ++ + I + ++PP + KN ++ +E I++L E+
Sbjct: 862 QRPPSVDSIIRSFIHESSMSRAQSPPVPAR-KNQLRAEEEKKNVIMELSEM 911
>gi|116174789 centrosome spindle pole associated protein 1 isoform a
[Homo sapiens]
Length = 1256
Score = 48.1 bits (113), Expect = 3e-05
Identities = 51/191 (26%), Positives = 92/191 (48%), Gaps = 25/191 (13%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEE-----MERLEIQRIEKEKWHRL-- 57
K+++ + ERL++ +E+EERRL E+ AR++ E EE E+ E QR++ E+ RL
Sbjct: 782 KQREEAERERLRIAEEKEERRL-AEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE 840
Query: 58 -EAKDLERRNEELEELYLLE---------RCFPEAEKLKQETKLLSQWKHYIQCDGSPDP 107
K+ ER+ +E EE Y L+ E + ++Q + ++ ++ I P
Sbjct: 841 ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 900
Query: 108 SVAQEMNTFISLWKEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQE 167
SV + +FI + + + K L E+ K +++E Q ++ +E
Sbjct: 901 SVDSIIRSFIH--ESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQ----LRSEE 954
Query: 168 SILQLQELLHL 178
LQ + LLH+
Sbjct: 955 RRLQ-ERLLHM 964
Score = 40.8 bits (94), Expect = 0.004
Identities = 39/171 (22%), Positives = 78/171 (45%), Gaps = 15/171 (8%)
Query: 19 QEEEERRLKEEEEARLKYEKEEME------RLEIQRIEKEKWHRLEAKDLERRNEELEEL 72
Q EE+++ +E E RL+ +E+ E R IQ+ +E+ + K+ E+R + E +
Sbjct: 777 QIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHI 836
Query: 73 YLLERCFPEAEKLK--QETKLLSQWKHYIQCDG--SPDPSVAQEMNTFISLWKEKTNETF 128
L E EAE+ K +E K Q +HY + D + ++ + + + K
Sbjct: 837 RLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKL 896
Query: 129 EEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQES----ILQLQEL 175
+ ++ + I + ++PP + KN ++ +E I++L E+
Sbjct: 897 QRPPSVDSIIRSFIHESSMSRAQSPPVPAR-KNQLRAEEEKKNVIMELSEM 946
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 47.8 bits (112), Expect = 4e-05
Identities = 56/230 (24%), Positives = 104/230 (45%), Gaps = 16/230 (6%)
Query: 13 ERLKLLQE---EEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLE---AKDLERRN 66
ERL+ +E E+E RL+E EE + E+ E+ E R ++E+ H E + ER
Sbjct: 234 ERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLR 293
Query: 67 EELEELYLLERCFPEAEK--LKQETKLLSQWKHYIQCDGSP-DPSVAQEMNTFISLWKEK 123
E+ E L E E E+ +QE +L Q + + + P + +E+ + +E+
Sbjct: 294 EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLE--QER 351
Query: 124 TNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFGVA 183
E E ++E+ +++ + E L+ L L + +Q E + +L+ +L L +
Sbjct: 352 RQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLELGWEAL 411
Query: 184 TEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSET 233
E + S +L++ N + ++ V LKK+ R SE+
Sbjct: 412 YEQRAEPRSGFEELNNENKSTLQLEQQV-----KELKKSGGAEEPRGSES 456
Score = 37.0 bits (84), Expect = 0.064
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 4/88 (4%)
Query: 8 KVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNE 67
+V + L LL +E RL+E+EE RL+ ++E + E + E+E+ R + + L + E
Sbjct: 183 EVENNQMLSLLNRRQEERLREQEE-RLREQEERLREQEERLCEQEERLREQEERLREQEE 241
Query: 68 ELEELYLLERCFPEAEKL-KQETKLLSQ 94
L E ER E+L +QE +L Q
Sbjct: 242 RLCEQE--ERLREHEERLCEQEERLCEQ 267
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 47.4 bits (111), Expect = 5e-05
Identities = 70/357 (19%), Positives = 154/357 (43%), Gaps = 27/357 (7%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKD-LE 63
++++ + E K L+++ E + EEE R + E+ E + E++R + +W R ++ L
Sbjct: 400 EQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLN 459
Query: 64 RRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWK-- 121
+RN+E E++ +L+ + + L+ E + L+ KH ++ Q++ ++ +
Sbjct: 460 QRNKEQEDIVVLK---AKKKTLEFELEALNDKKHQLE-------GKLQDIRCRLTTQRQE 509
Query: 122 -EKTNETFE-EVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLK 179
E TN++ E + E + + L E + + P + + + Q Q++ L L+ LK
Sbjct: 510 IESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLK 569
Query: 180 FGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEI 239
+ + L +Q LD E K + + ++ LK+ + + + Q E
Sbjct: 570 RALEAKELARQ-HLRDQLDEVEKETRSKLQEIDIFN-NQLKELREIHNKQQLQKQKSMEA 627
Query: 240 PRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTE---------LVKDDVKNVEK 290
R L + +++ A K++ V + L +++ E+
Sbjct: 628 ER-LKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREE 686
Query: 291 AISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVL 347
++ K+ EE +QE L + E + ++ S+AE+ I + +KV+
Sbjct: 687 SVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPWSTAEKGPLTISAQENVKVV 743
Score = 39.7 bits (91), Expect = 0.010
Identities = 75/352 (21%), Positives = 152/352 (43%), Gaps = 54/352 (15%)
Query: 7 KKVTKAERLKLLQEEEERRLKE----EEEARLKYEKEEMERLEIQRIEKEKWHRLE---- 58
KK ER L E+ + L E E+E + E+ E ER E +R E+E+ +LE
Sbjct: 353 KKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQ 412
Query: 59 ---AKDLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNT 115
++LER+ EE E +ER EA K + E + +W+ + + + QE
Sbjct: 413 LEKQRELERQREE-ERRKEIER--REAAKRELERQRQLEWERNRRQELLNQRNKEQEDIV 469
Query: 116 FISLWKEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQEL 175
+ K+ E + +K + ++ ++ L T +++ N + L++ E+
Sbjct: 470 VLKAKKKTLEFELEALNDKKHQLEGKLQDIR-CRLTTQRQEIESTN----KSRELRIAEI 524
Query: 176 LHLKFGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQI 235
HL + L+++ + + ++I ++ + +++N HR +
Sbjct: 525 THL------QQQLQESQQM-------LGRLIPEKQILNDQLKQVQQNSLHRDSLVT---- 567
Query: 236 GFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKE 295
+ R L ++A + L D V KE S + E+ D+ N + +E
Sbjct: 568 ---LKRALEAKELARQHLRDQLDEV---------EKETRSKLQEI---DIFNNQLKELRE 612
Query: 296 VEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVL 347
+ +KQQ + ++ E +K +E++ I +++ +EE++ ER+ + L
Sbjct: 613 I--HNKQQLQKQKSMEAERLKQKEQERKI-IELEKQKEEAQRRAQERDKQWL 661
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 47.4 bits (111), Expect = 5e-05
Identities = 70/357 (19%), Positives = 154/357 (43%), Gaps = 27/357 (7%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKD-LE 63
++++ + E K L+++ E + EEE R + E+ E + E++R + +W R ++ L
Sbjct: 400 EQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLN 459
Query: 64 RRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWK-- 121
+RN+E E++ +L+ + + L+ E + L+ KH ++ Q++ ++ +
Sbjct: 460 QRNKEQEDIVVLK---AKKKTLEFELEALNDKKHQLE-------GKLQDIRCRLTTQRQE 509
Query: 122 -EKTNETFE-EVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLK 179
E TN++ E + E + + L E + + P + + + Q Q++ L L+ LK
Sbjct: 510 IESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLK 569
Query: 180 FGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEI 239
+ + L +Q LD E K + + ++ LK+ + + + Q E
Sbjct: 570 RALEAKELARQ-HLRDQLDEVEKETRSKLQEIDIFN-NQLKELREIHNKQQLQKQKSMEA 627
Query: 240 PRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTE---------LVKDDVKNVEK 290
R L + +++ A K++ V + L +++ E+
Sbjct: 628 ER-LKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREE 686
Query: 291 AISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVL 347
++ K+ EE +QE L + E + ++ S+AE+ I + +KV+
Sbjct: 687 SVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPWSTAEKGPLTISAQENVKVV 743
Score = 39.7 bits (91), Expect = 0.010
Identities = 75/352 (21%), Positives = 152/352 (43%), Gaps = 54/352 (15%)
Query: 7 KKVTKAERLKLLQEEEERRLKE----EEEARLKYEKEEMERLEIQRIEKEKWHRLE---- 58
KK ER L E+ + L E E+E + E+ E ER E +R E+E+ +LE
Sbjct: 353 KKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQ 412
Query: 59 ---AKDLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNT 115
++LER+ EE E +ER EA K + E + +W+ + + + QE
Sbjct: 413 LEKQRELERQREE-ERRKEIER--REAAKRELERQRQLEWERNRRQELLNQRNKEQEDIV 469
Query: 116 FISLWKEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQEL 175
+ K+ E + +K + ++ ++ L T +++ N + L++ E+
Sbjct: 470 VLKAKKKTLEFELEALNDKKHQLEGKLQDIR-CRLTTQRQEIESTN----KSRELRIAEI 524
Query: 176 LHLKFGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQI 235
HL + L+++ + + ++I ++ + +++N HR +
Sbjct: 525 THL------QQQLQESQQM-------LGRLIPEKQILNDQLKQVQQNSLHRDSLVT---- 567
Query: 236 GFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKE 295
+ R L ++A + L D V KE S + E+ D+ N + +E
Sbjct: 568 ---LKRALEAKELARQHLRDQLDEV---------EKETRSKLQEI---DIFNNQLKELRE 612
Query: 296 VEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVL 347
+ +KQQ + ++ E +K +E++ I +++ +EE++ ER+ + L
Sbjct: 613 I--HNKQQLQKQKSMEAERLKQKEQERKI-IELEKQKEEAQRRAQERDKQWL 661
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 47.4 bits (111), Expect = 5e-05
Identities = 83/368 (22%), Positives = 168/368 (45%), Gaps = 62/368 (16%)
Query: 14 RLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELY 73
R + + E + R E E + KE+ ++ + KE+ R D++ RNEE+E+L
Sbjct: 2099 RFQPISEHQTR----EVEQLANHLKEKTDKCSELLLSKEQLQR----DIQERNEEIEKLE 2150
Query: 74 LLERCFPEAEKLKQET-KLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNETFEEVI 132
R +A + +T + + KH+ + P E++ + L E+ + +
Sbjct: 2151 FRVRELEQALLVSADTFQKVEDRKHFGAVEAKP------ELSLEVQLQAER-----DAID 2199
Query: 133 EKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFGVATEILLKQAS 192
K K + NL E+L+ E L++KN E + QL L EI K+++
Sbjct: 2200 RKEKEITNLEEQLEQFREE-----LENKN-----EEVQQLHMQL--------EIQKKEST 2241
Query: 193 T-LADLDSGNMEKVIKD--ENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRILATSDIA 249
T L +L+ N K+ KD E + L + + + + + V F + +I+ ++
Sbjct: 2242 TRLQELEQEN--KLFKDDMEKLGLAIKESDAMSTQDQHVLFG------KFAQIIQEKEVE 2293
Query: 250 VRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQERGSHL 309
+ L+ + ++T +K EL++D +E +S ++E ++ R +
Sbjct: 2294 IDQLNEQVTKLQQQLKITTDNK-VIEEKNELIRDLETQIECLMS---DQECVKRNREEEI 2349
Query: 310 IQEEEI--KVEEEQGDIEVKMS----SAEEESEAIKCEREMKVLSETVSAAQLLLVENSS 363
Q E+ K+++E +I K S S EE++++K + ++ V++E ++ Q VE ++
Sbjct: 2350 EQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDV-VIAEKLALEQ--QVETAN 2406
Query: 364 EKPDFFED 371
E+ F ++
Sbjct: 2407 EEMTFMKN 2414
Score = 37.0 bits (84), Expect = 0.064
Identities = 43/219 (19%), Positives = 92/219 (42%), Gaps = 33/219 (15%)
Query: 156 DLQDKNIIQYQESILQLQELLHLKFGVATEILLKQASTLADLDSGNMEKVIKDENVTLYV 215
+L++ + E + QLQE E +KQ + + N+++ ++++ T+
Sbjct: 177 ELEEMRVTYGTEGLQQLQEF---------EAAIKQRDGIITQLTANLQQARREKDETMRE 227
Query: 216 WANLKKNPRHRSVRFSETQIGFEIPRILATSDIAVRLLH------THYDHVSA----LHP 265
+ L + + ++F + Q E R S A LL TH + L
Sbjct: 228 FLELTEQSQKLQIQFQQLQAS-ETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLED 286
Query: 266 VSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIE 325
+++T ++ L ++ +K E K+VE +K++ IQE+E +E E
Sbjct: 287 YQKKKEDFTMQISFL-QEKIKVYEMEQDKKVENSNKEE------IQEKETIIE------E 333
Query: 326 VKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVENSSE 364
+ EEE + ++ + ++ + + Q +V+ + E
Sbjct: 334 LNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQE 372
Score = 37.0 bits (84), Expect = 0.064
Identities = 48/197 (24%), Positives = 93/197 (47%), Gaps = 34/197 (17%)
Query: 17 LLQEEEERRLKEEE--EARLKYEKEEMERLEIQRIEKEKWHRLEAKD--LERRNEELEEL 72
L QEE+E+ E+E E +LK E E + E + +EK+ +LEA++ L+ + LE++
Sbjct: 731 LRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDM 790
Query: 73 YLLERCFPEAEKL------KQETKLLSQWKHYI------------QCDGSPDPSVAQEMN 114
+ + E+L K ++K S W+ I QC + + ++ N
Sbjct: 791 LKIHTPVSQEERLIFLDSIKSKSK-DSVWEKEIEILIEENEDLKQQCI-QLNEEIEKQRN 848
Query: 115 TFISLWKEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQE 174
TF S ++ ++E+ E+ +L + + L+ D ++K ++Y+ + L E
Sbjct: 849 TF-SFAEKNFEVNYQELQEEYACLLKVKDDLE---------DSKNKQELEYKSKLKALNE 898
Query: 175 LLHLKFGVATEILLKQA 191
LHL+ T + +K +
Sbjct: 899 ELHLQRINPTTVKMKSS 915
Score = 37.0 bits (84), Expect = 0.064
Identities = 79/397 (19%), Positives = 154/397 (38%), Gaps = 65/397 (16%)
Query: 31 EARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELYL-----LERCFPEAEKL 85
E +L+ E++ ++R E + E+ ++LE +NEE+++L++ + ++L
Sbjct: 2188 EVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQEL 2247
Query: 86 KQETKLLSQWKHYI-QCDGSPDPSVAQEMNTFISLWKEKTNETFEEVIEKSKVVLNLIEK 144
+QE KL + D Q+ + + + E E+ + ++ V L ++
Sbjct: 2248 EQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQ 2307
Query: 145 LKFIL--------------LETP-PCDLQDKNIIQ--YQESILQLQELLH------LKFG 181
LK LET C + D+ ++ +E I QL E++ G
Sbjct: 2308 LKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIG 2367
Query: 182 VATEILLKQASTLADLDSGNMEKVIKDE----------NVTLYVWANLKKNPRHRSVRFS 231
T + S AD ++ VI ++ N + N+ K + + +
Sbjct: 2368 QKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLT 2427
Query: 232 ETQIGFEIPR--ILATSDIAVRLLHTHYDHVSALHP-----------VSTPSKEYTSAVT 278
+ + R + I ++ DH+S P S ++ Y +
Sbjct: 2428 QELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFE 2487
Query: 279 ELVKDDVKNVEKAISKEVEEESKQQERGSHLIQ-EEEIKVEEEQGDIEVKMSSAEEESEA 337
E K + N+E ++ ++ ES + L Q ++IK +EQG E +M
Sbjct: 2488 ENGKGSIINLE---TRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQK------ 2538
Query: 338 IKCEREMKVLSETVSAAQL--LLVENSSEKPDFFEDN 372
K K++ E V+AA + + +E E F +DN
Sbjct: 2539 -KIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDN 2574
Score = 35.8 bits (81), Expect = 0.14
Identities = 62/330 (18%), Positives = 133/330 (40%), Gaps = 26/330 (7%)
Query: 13 ERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKD-LERRNEELEE 71
E++K+ + E++++++ + ++ ++ +E L + IE+EK LE KD L ++ L E
Sbjct: 303 EKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEK-KTLELKDKLTTADKLLGE 361
Query: 72 LYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNETFEEV 131
L E+ + +++K L+ K Q + + Q M T L K ++ E
Sbjct: 362 LQ--EQIVQKNQEIKNMKLELTNSK---QKERQSSEEIKQLMGTVEELQKRNHKDSQFET 416
Query: 132 IEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQL-QELLHLKFGVATEILLKQ 190
++ KL+ + E Y + I+Q+ QEL+ E+ +
Sbjct: 417 DIVQRMEQETQRKLEQLRAELDE---------MYGQQIVQMKQELIRQHMAQMEEMKTRH 467
Query: 191 ASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRILATSDIAV 250
+ + + ++ + L A + N + + + ++ E+ IL
Sbjct: 468 KGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQ 527
Query: 251 RLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISK--EVEEESKQQERGSH 308
R L + +S S+E + + + + +A VE+ + S
Sbjct: 528 RQLEDLVEELSF-------SREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASE 580
Query: 309 LIQEEEIKVEEEQGDIEVKMSSAEEESEAI 338
+E E+K E E + ++K+ E+E A+
Sbjct: 581 SRKELELKHEAEVTNYKIKLEMLEKEKNAV 610
Score = 34.3 bits (77), Expect = 0.41
Identities = 59/331 (17%), Positives = 145/331 (43%), Gaps = 45/331 (13%)
Query: 19 QEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELYLLERC 78
Q +EER L ++ +K E +E+ +Q EK +LE +C
Sbjct: 1968 QIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEV-----------------QC 2010
Query: 79 FPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNETFEEVIEKSKVV 138
+AEK++ + L + ++ D V ++++ FI L +EK E ++ ++++ +
Sbjct: 2011 --QAEKVRDD---LQKQVKALEID------VEEQVSRFIELEQEKNTELM-DLRQQNQAL 2058
Query: 139 LNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFGVATEILLKQASTLADLD 198
+EK++ L E ++++ Q + L+ Q + +F +E ++ LA+
Sbjct: 2059 EKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLAN-- 2116
Query: 199 SGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGF-EIPRILATSDIAVRLL--HT 255
++++ + L L+++ + R+ + + E+ + L S + +
Sbjct: 2117 --HLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRK 2174
Query: 256 HYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAIS---KEVEEESKQQERGSHLIQE 312
H+ V A +S + +D + EK I+ +++E+ ++ E + +Q+
Sbjct: 2175 HFGAVEAKPELS------LEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQ 2228
Query: 313 EEIKVEEEQGDIEVKMSSAEEESEAIKCERE 343
+++E ++ + ++ E+E++ K + E
Sbjct: 2229 LHMQLEIQKKESTTRLQELEQENKLFKDDME 2259
Score = 31.2 bits (69), Expect = 3.5
Identities = 71/344 (20%), Positives = 144/344 (41%), Gaps = 52/344 (15%)
Query: 31 EARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEEL----EELYLLERCFPEAEKLK 86
+A L KE+ E+L+ + + KE KDL + + L E+L +LE+ E E
Sbjct: 2702 KAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEK---EDETEV 2758
Query: 87 QETKLLSQWKHYIQCDGSPDP-----SVAQEMNTFISLWKEKTNETFEEVIEKSKVVLNL 141
QE+K C P P S+A + + + + +N+T + +++ + + +NL
Sbjct: 2759 QESKK--------ACMFEPLPIKLSKSIASQTDGTLKI--SSSNQTPQILVKNAGIQINL 2808
Query: 142 IEKLKFILLETPPCDLQD--KNIIQYQESILQLQELLHLKFGVATEILLKQASTLADLDS 199
+ C ++ + I Q+ E I ++QEL A EIL ++ +++ ++
Sbjct: 2809 QSE----------CSSEEVTEIISQFTEKIEKMQEL------HAAEILDMESRHISETET 2852
Query: 200 GNME-----KVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRILATSDIAVRLLH 254
E +++K+E TL ++ S+ ++ I ++ +
Sbjct: 2853 LKREHYVAVQLLKEECGTLKAVIQCLRSKEGSSIPELAHSDAYQTREICSSDSGSDWGQG 2912
Query: 255 THYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEE-----ESKQQERGSHL 309
+ H S E + + T+ +K + +A+ E + ES + H
Sbjct: 2913 IYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHS 2972
Query: 310 IQE-EEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVS 352
IQ+ E +EE + I +SS ++ ++ +RE +V + S
Sbjct: 2973 IQQVSEPWLEERKAYINT-ISSLKDLITKMQLQREAEVYDSSQS 3015
Score = 30.4 bits (67), Expect = 6.0
Identities = 33/120 (27%), Positives = 56/120 (46%), Gaps = 6/120 (5%)
Query: 29 EEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELYLLERCFPEAEKLKQE 88
E L EKE++E E +EKEK LE + L NE+ + +R + E LK
Sbjct: 2617 EMHTSLILEKEQVEIAEKNVLEKEK-KLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTT 2675
Query: 89 TKLL---SQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNETFEEVIEKSKVVLNLIEKL 145
T+L + + + + SVA + ++ +KEK + EE++ K + +L + L
Sbjct: 2676 TELFHSNEESGFFNELEALRAESVATKAE--LASYKEKAEKLQEELLVKETNMTSLQKDL 2733
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 47.0 bits (110), Expect = 6e-05
Identities = 77/368 (20%), Positives = 156/368 (42%), Gaps = 52/368 (14%)
Query: 6 KKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERR 65
+ K+ KAE L++ E+ +E E ++K E+E L+ + E+ K L+
Sbjct: 668 RSKLDKAEDQHLVEMEDTLNKLQEAEIKVK----ELEVLQAKCNEQTKVIDNFTSQLKAT 723
Query: 66 NEELEELYLLERCFPEAE----KLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWK 121
E+L +L L + E + KL+Q+ + + +++ + + + S A + + +
Sbjct: 724 EEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRE 783
Query: 122 EKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLK-- 179
K E + E S+V L ++L+ + + + + Q S+ + LH K
Sbjct: 784 LKLTNLQENLSEVSQVKETLEKELQILKEKFAEAS---EEAVSVQRSMQETVNKLHQKEE 840
Query: 180 -FGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFE 238
F + + L K LAD+++ EK ++E + ++ ++ +
Sbjct: 841 QFNMLSSDLEKLRENLADMEAKFREKDEREEQLIK-----------------AKEKLEND 883
Query: 239 IPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKA--ISKEV 296
I I+ S D+ S L ++ + V EL K E A + K +
Sbjct: 884 IAEIMKMSG----------DNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSI 933
Query: 297 E------EESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSET 350
E E+S+Q+ H +EE+ ++E + D+E KM ++ + + +K E + SET
Sbjct: 934 EDMTVKAEQSQQEAAKKH--EEEKKELERKLSDLEKKMETSHNQCQELKARYE-RATSET 990
Query: 351 VSAAQLLL 358
+ + +L
Sbjct: 991 KTKHEEIL 998
Score = 38.1 bits (87), Expect = 0.029
Identities = 72/373 (19%), Positives = 152/373 (40%), Gaps = 57/373 (15%)
Query: 10 TKAERLKLLQEEEERRLKEEEEARLKYEKEEME--RLEIQRIEKEKWHRLEAKDLERRNE 67
T+ E+++L + E L+ ++++ +EME R ++ ++ KEK + LEA + + +
Sbjct: 615 TQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEA--IRSKLD 672
Query: 68 ELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNET 127
+ E+ +L+E + QE ++ + +Q K NE
Sbjct: 673 KAEDQHLVE--MEDTLNKLQEAEIKVKELEVLQA---------------------KCNE- 708
Query: 128 FEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFGVATEIL 187
++KV+ N +LK + D K + + + +L++ L A E
Sbjct: 709 ------QTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLE-----AAEKQ 757
Query: 188 LKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSV--RFSETQIGFEIPRILAT 245
+K + +S + ++ NL++N S E ++ +
Sbjct: 758 IKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEA 817
Query: 246 SDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQER 305
S+ AV + + + V+ LH +S ++EK + E+K +E+
Sbjct: 818 SEEAVSVQRSMQETVNKLHQKEEQFNMLSS-----------DLEKLRENLADMEAKFREK 866
Query: 306 GSHLIQEEEIKVEEE-QGDI-EVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVENSS 363
+E+ IK +E+ + DI E+ S + S+ K E+++ V QL L + ++
Sbjct: 867 DER--EEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTK-AN 923
Query: 364 EKPDFFEDNVVDL 376
E F + ++ D+
Sbjct: 924 ENASFLQKSIEDM 936
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 47.0 bits (110), Expect = 6e-05
Identities = 77/368 (20%), Positives = 156/368 (42%), Gaps = 52/368 (14%)
Query: 6 KKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERR 65
+ K+ KAE L++ E+ +E E ++K E+E L+ + E+ K L+
Sbjct: 703 RSKLDKAEDQHLVEMEDTLNKLQEAEIKVK----ELEVLQAKCNEQTKVIDNFTSQLKAT 758
Query: 66 NEELEELYLLERCFPEAE----KLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWK 121
E+L +L L + E + KL+Q+ + + +++ + + + S A + + +
Sbjct: 759 EEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRE 818
Query: 122 EKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLK-- 179
K E + E S+V L ++L+ + + + + Q S+ + LH K
Sbjct: 819 LKLTNLQENLSEVSQVKETLEKELQILKEKFAEAS---EEAVSVQRSMQETVNKLHQKEE 875
Query: 180 -FGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFE 238
F + + L K LAD+++ EK ++E + ++ ++ +
Sbjct: 876 QFNMLSSDLEKLRENLADMEAKFREKDEREEQLIK-----------------AKEKLEND 918
Query: 239 IPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKA--ISKEV 296
I I+ S D+ S L ++ + V EL K E A + K +
Sbjct: 919 IAEIMKMSG----------DNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSI 968
Query: 297 E------EESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSET 350
E E+S+Q+ H +EE+ ++E + D+E KM ++ + + +K E + SET
Sbjct: 969 EDMTVKAEQSQQEAAKKH--EEEKKELERKLSDLEKKMETSHNQCQELKARYE-RATSET 1025
Query: 351 VSAAQLLL 358
+ + +L
Sbjct: 1026 KTKHEEIL 1033
Score = 38.1 bits (87), Expect = 0.029
Identities = 72/373 (19%), Positives = 152/373 (40%), Gaps = 57/373 (15%)
Query: 10 TKAERLKLLQEEEERRLKEEEEARLKYEKEEME--RLEIQRIEKEKWHRLEAKDLERRNE 67
T+ E+++L + E L+ ++++ +EME R ++ ++ KEK + LEA + + +
Sbjct: 650 TQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEA--IRSKLD 707
Query: 68 ELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNET 127
+ E+ +L+E + QE ++ + +Q K NE
Sbjct: 708 KAEDQHLVE--MEDTLNKLQEAEIKVKELEVLQA---------------------KCNE- 743
Query: 128 FEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFGVATEIL 187
++KV+ N +LK + D K + + + +L++ L A E
Sbjct: 744 ------QTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLE-----AAEKQ 792
Query: 188 LKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSV--RFSETQIGFEIPRILAT 245
+K + +S + ++ NL++N S E ++ +
Sbjct: 793 IKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEA 852
Query: 246 SDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQER 305
S+ AV + + + V+ LH +S ++EK + E+K +E+
Sbjct: 853 SEEAVSVQRSMQETVNKLHQKEEQFNMLSS-----------DLEKLRENLADMEAKFREK 901
Query: 306 GSHLIQEEEIKVEEE-QGDI-EVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVENSS 363
+E+ IK +E+ + DI E+ S + S+ K E+++ V QL L + ++
Sbjct: 902 DER--EEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTK-AN 958
Query: 364 EKPDFFEDNVVDL 376
E F + ++ D+
Sbjct: 959 ENASFLQKSIEDM 971
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 47.0 bits (110), Expect = 6e-05
Identities = 94/423 (22%), Positives = 183/423 (43%), Gaps = 76/423 (17%)
Query: 4 SKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLE 63
S + KV + KL E+ +++ E+E L+ KEE +L++ +E+ K + K E
Sbjct: 301 SAQDKVLREAENKL---EQSQKMVIEKEQSLQESKEECIKLKVDLLEQTK----QGKRAE 353
Query: 64 R-RNEELEELYLLERCFPE--------AEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMN 114
R RNE L L + F + EK++ E ++L ++ C+ + + +
Sbjct: 354 RQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILE--RNLTNCE-KENKRLQERCG 410
Query: 115 TF---ISLWKEKTNETFEE-----------VIEKSKVVLNLIEKLKFIL-LETPPCDLQD 159
+ + + KEK + EE ++ S+V+ L E + IL LE+ +L++
Sbjct: 411 LYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLES---ELEN 467
Query: 160 KNIIQYQESILQLQELLHLKFGVATE----ILLKQASTLADLDSGNMEKVIKDENVTLYV 215
K+ I ++ + E LK VA + L +Q + ++ ++EK+I + +
Sbjct: 468 KDEI-LRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKREL 526
Query: 216 WANLKKNPRHRSVRFSETQ---IGFEIPRILATSDIAVRLLHTHYDHVSALHP------- 265
+ +++ FS + IG L S++ ++L + + LH
Sbjct: 527 FGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAE-IQKLHANLTANQL 585
Query: 266 --------VSTPSKEYTSAVTELVK-------DDVKNV-EKAISKEVEEESKQQERGSHL 309
S S + +S TE VK + VK+ + ++K+ E+E ++ G
Sbjct: 586 SQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEE 645
Query: 310 IQEEEIKVEEEQGDIEVKMSSAEEESEAI------KCEREMKVLSE-TVSAAQLLLVENS 362
++ + I++E E D++V M+ + + I K K+ SE T +QLL +E
Sbjct: 646 LRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQ 705
Query: 363 SEK 365
E+
Sbjct: 706 LEE 708
Score = 34.3 bits (77), Expect = 0.41
Identities = 85/380 (22%), Positives = 170/380 (44%), Gaps = 66/380 (17%)
Query: 28 EEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEE---------------- 71
E E+ L +EK + LE + +++ RLEA+ LE+++++ +E
Sbjct: 744 EHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQ-LEKKDQQFKEQEKTMSMLQQDIICKQ 802
Query: 72 --LYLLERCFPEAE-KLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEK----- 123
L L+R E++ ++K+E + +Q S + +++++ + + KE+
Sbjct: 803 HHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHL 862
Query: 124 -----TNETFEEVI-EKSKVVLNLIEKLKF---ILLETPPCDLQDKNIIQYQESILQLQE 174
E FE+ + +KS+ V L ++LK L ET ++ ++ +Q Q+ +LQ +
Sbjct: 863 NQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQET 922
Query: 175 LLHLKFGVATEILLKQASTLAD----LDSGNMEKVIKDEN--VTLYVWANLKKNPRHRSV 228
+ + + L KQ S L + EK+ K E + A+LK R + +
Sbjct: 923 IRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLK---RQKVI 979
Query: 229 RFSET--QIGFEIPRIL-ATSDIAVRLLHTHYD------HVSALHPV----STPSKEYTS 275
+ T Q+ E+ + S + ++H D H+S L + T ++ T+
Sbjct: 980 ELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTN 1039
Query: 276 AVTELVK----DDVKNVEKAISKEVEEESKQQERG---SHLIQEEEIK--VEEEQGDIEV 326
AV EL K + + E +EV E Q G S L Q +E++ +++ Q +E
Sbjct: 1040 AVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEE 1099
Query: 327 KMSSAEE-ESEAIKCEREMK 345
K ++ ++ +E +C+ E++
Sbjct: 1100 KYTTIKDLTAELRECKMEIE 1119
Score = 31.6 bits (70), Expect = 2.7
Identities = 20/78 (25%), Positives = 40/78 (51%)
Query: 13 ERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEEL 72
ER + +E E +KE+E+ KE ++ + R+ +E+ + E R+++++
Sbjct: 1221 ERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQ 1280
Query: 73 YLLERCFPEAEKLKQETK 90
+ER E E +KQ +K
Sbjct: 1281 REIERLSSELEDMKQLSK 1298
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 47.0 bits (110), Expect = 6e-05
Identities = 41/133 (30%), Positives = 64/133 (48%), Gaps = 6/133 (4%)
Query: 4 SKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLE 63
+++K+ +A RL+ LQ+EEE R +E K ++EE ERL R E E ++ E
Sbjct: 637 ARRKQEEEARRLRWLQQEEEER--RHQELLQKKKEEEQERL---RKAAEAKRLAEQREQE 691
Query: 64 RRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEK 123
RR +E E E+ E E+ +QE +L Q + Q + QE + L KE+
Sbjct: 692 RREQERREQERREQERREQERREQERQLAEQERRREQ-ERLQAERELQEREKALRLQKEQ 750
Query: 124 TNETFEEVIEKSK 136
EE +K +
Sbjct: 751 LQRELEEKKKKEE 763
Score = 36.2 bits (82), Expect = 0.11
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 24/104 (23%)
Query: 7 KKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRI----------------- 49
+K +A+RL +E+E R + E+ R + E+ E ER E +R
Sbjct: 676 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 735
Query: 50 ---EKEKWHRLEAKDLERRNEEL----EELYLLERCFPEAEKLK 86
E+EK RL+ + L+R EE E+ L ER E ++ K
Sbjct: 736 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 779
Score = 35.4 bits (80), Expect = 0.19
Identities = 30/102 (29%), Positives = 59/102 (57%), Gaps = 14/102 (13%)
Query: 1 MSGSKKKKVTKAERLKLLQEEEERRLKE---EEEARLKYEKEEMERLEIQRIEKEKWHR- 56
M KKK++ ++ + E+ E+ +E EE+A+ K ++ME +E +R ++E+ R
Sbjct: 591 MKEEKKKQIE--QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 648
Query: 57 --LEAKDLERRNEELEELYLLERCFPEAEKLKQ--ETKLLSQ 94
L+ ++ ERR++EL L ++ E E+L++ E K L++
Sbjct: 649 RWLQQEEEERRHQEL----LQKKKEEEQERLRKAAEAKRLAE 686
Score = 35.0 bits (79), Expect = 0.24
Identities = 24/65 (36%), Positives = 36/65 (55%), Gaps = 6/65 (9%)
Query: 28 EEEEARLKY--EKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELYLLERCFPEAEKL 85
E+E RL+ KEE E+L Q++E++K RLE L+R + L ER E++
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER----VEQM 591
Query: 86 KQETK 90
K+E K
Sbjct: 592 KEEKK 596
Score = 33.1 bits (74), Expect = 0.92
Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 9/73 (12%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKE---------EEEARLKYEKEEMERLEIQRIEKEKWH 55
++++ + E+ + L E+E RR +E E E L+ +KE+++R ++ +KE+
Sbjct: 706 ERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 765
Query: 56 RLEAKDLERRNEE 68
RL + L+ E+
Sbjct: 766 RLAERQLQEEQEK 778
Score = 32.0 bits (71), Expect = 2.1
Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 13/81 (16%)
Query: 278 TELVKDDVKNVEKAISK-------EVEEESKQQERGSHL--IQEEEIKVEEEQGDIEVKM 328
TE K++ EKA K EVE KQ+E L +Q+EE EE+ E+
Sbjct: 610 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE----EERRHQELLQ 665
Query: 329 SSAEEESEAIKCEREMKVLSE 349
EEE E ++ E K L+E
Sbjct: 666 KKKEEEQERLRKAAEAKRLAE 686
Score = 31.2 bits (69), Expect = 3.5
Identities = 26/103 (25%), Positives = 53/103 (51%), Gaps = 18/103 (17%)
Query: 6 KKKVTKAERLKLLQEEEE-RRLKEEEEARLKYEKEEMERLE-----------IQRIEKEK 53
+K+ + E L+ +E E+ RR K EE+ R + E+ +++R E ++++++EK
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 595
Query: 54 WHRLEAK--DLERRNEELEELYLLERCFPEAEKLKQETKLLSQ 94
++E K ++ + E+ +E ER E K K K + +
Sbjct: 596 KKQIEQKFAQIDEKTEKAKE----ERLAEEKAKKKAAAKKMEE 634
Score = 30.4 bits (67), Expect = 6.0
Identities = 20/78 (25%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 290 KAISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAE--EESEAIKCEREMKVL 347
K ++++ E+E ++QER +E+E + E+E+ + E +++ E E E ++ ERE++
Sbjct: 682 KRLAEQREQERREQERREQERREQE-RREQERREQERQLAEQERRREQERLQAERELQER 740
Query: 348 SETVSAAQLLLVENSSEK 365
+ + + L EK
Sbjct: 741 EKALRLQKEQLQRELEEK 758
Score = 30.0 bits (66), Expect = 7.8
Identities = 25/99 (25%), Positives = 56/99 (56%), Gaps = 11/99 (11%)
Query: 8 KVTKAERLKLLQEEEER--RLKEEEEARLKYE----KEEMERLEIQRIEKEKWHRLEA-- 59
K+ + ERL+ + + ER ++KEE++ +++ + E+ E+ + +R+ +EK + A
Sbjct: 571 KLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK 630
Query: 60 --KDLERRNEELEELYLLERCFPEAEKLKQETKLLSQWK 96
+++E R ++ EE L R + E+ ++ +LL + K
Sbjct: 631 KMEEVEARRKQEEEARRL-RWLQQEEEERRHQELLQKKK 668
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 47.0 bits (110), Expect = 6e-05
Identities = 41/133 (30%), Positives = 64/133 (48%), Gaps = 6/133 (4%)
Query: 4 SKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLE 63
+++K+ +A RL+ LQ+EEE R +E K ++EE ERL R E E ++ E
Sbjct: 633 ARRKQEEEARRLRWLQQEEEER--RHQELLQKKKEEEQERL---RKAAEAKRLAEQREQE 687
Query: 64 RRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEK 123
RR +E E E+ E E+ +QE +L Q + Q + QE + L KE+
Sbjct: 688 RREQERREQERREQERREQERREQERQLAEQERRREQ-ERLQAERELQEREKALRLQKEQ 746
Query: 124 TNETFEEVIEKSK 136
EE +K +
Sbjct: 747 LQRELEEKKKKEE 759
Score = 37.0 bits (84), Expect = 0.064
Identities = 25/66 (37%), Positives = 37/66 (56%), Gaps = 6/66 (9%)
Query: 27 KEEEEARLKY--EKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELYLLERCFPEAEK 84
KE+E RL+ KEE E+L Q++E++K RLE L+R + L ER E+
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER----VEQ 586
Query: 85 LKQETK 90
+K+E K
Sbjct: 587 MKEEKK 592
Score = 36.2 bits (82), Expect = 0.11
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 24/104 (23%)
Query: 7 KKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRI----------------- 49
+K +A+RL +E+E R + E+ R + E+ E ER E +R
Sbjct: 672 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 731
Query: 50 ---EKEKWHRLEAKDLERRNEEL----EELYLLERCFPEAEKLK 86
E+EK RL+ + L+R EE E+ L ER E ++ K
Sbjct: 732 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 775
Score = 35.4 bits (80), Expect = 0.19
Identities = 30/102 (29%), Positives = 59/102 (57%), Gaps = 14/102 (13%)
Query: 1 MSGSKKKKVTKAERLKLLQEEEERRLKE---EEEARLKYEKEEMERLEIQRIEKEKWHR- 56
M KKK++ ++ + E+ E+ +E EE+A+ K ++ME +E +R ++E+ R
Sbjct: 587 MKEEKKKQIE--QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
Query: 57 --LEAKDLERRNEELEELYLLERCFPEAEKLKQ--ETKLLSQ 94
L+ ++ ERR++EL L ++ E E+L++ E K L++
Sbjct: 645 RWLQQEEEERRHQEL----LQKKKEEEQERLRKAAEAKRLAE 682
Score = 33.1 bits (74), Expect = 0.92
Identities = 27/104 (25%), Positives = 54/104 (51%), Gaps = 18/104 (17%)
Query: 5 KKKKVTKAERLKLLQEEEE-RRLKEEEEARLKYEKEEMERLE-----------IQRIEKE 52
K+K+ + E L+ +E E+ RR K EE+ R + E+ +++R E ++++++E
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
Query: 53 KWHRLEAK--DLERRNEELEELYLLERCFPEAEKLKQETKLLSQ 94
K ++E K ++ + E+ +E ER E K K K + +
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKE----ERLAEEKAKKKAAAKKMEE 630
Score = 33.1 bits (74), Expect = 0.92
Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 9/73 (12%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKE---------EEEARLKYEKEEMERLEIQRIEKEKWH 55
++++ + E+ + L E+E RR +E E E L+ +KE+++R ++ +KE+
Sbjct: 702 ERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
Query: 56 RLEAKDLERRNEE 68
RL + L+ E+
Sbjct: 762 RLAERQLQEEQEK 774
Score = 32.0 bits (71), Expect = 2.1
Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 13/81 (16%)
Query: 278 TELVKDDVKNVEKAISK-------EVEEESKQQERGSHL--IQEEEIKVEEEQGDIEVKM 328
TE K++ EKA K EVE KQ+E L +Q+EE EE+ E+
Sbjct: 606 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE----EERRHQELLQ 661
Query: 329 SSAEEESEAIKCEREMKVLSE 349
EEE E ++ E K L+E
Sbjct: 662 KKKEEEQERLRKAAEAKRLAE 682
Score = 30.4 bits (67), Expect = 6.0
Identities = 20/78 (25%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 290 KAISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAE--EESEAIKCEREMKVL 347
K ++++ E+E ++QER +E+E + E+E+ + E +++ E E E ++ ERE++
Sbjct: 678 KRLAEQREQERREQERREQERREQE-RREQERREQERQLAEQERRREQERLQAERELQER 736
Query: 348 SETVSAAQLLLVENSSEK 365
+ + + L EK
Sbjct: 737 EKALRLQKEQLQRELEEK 754
Score = 30.0 bits (66), Expect = 7.8
Identities = 25/99 (25%), Positives = 56/99 (56%), Gaps = 11/99 (11%)
Query: 8 KVTKAERLKLLQEEEER--RLKEEEEARLKYE----KEEMERLEIQRIEKEKWHRLEA-- 59
K+ + ERL+ + + ER ++KEE++ +++ + E+ E+ + +R+ +EK + A
Sbjct: 567 KLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK 626
Query: 60 --KDLERRNEELEELYLLERCFPEAEKLKQETKLLSQWK 96
+++E R ++ EE L R + E+ ++ +LL + K
Sbjct: 627 KMEEVEARRKQEEEARRL-RWLQQEEEERRHQELLQKKK 664
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 46.6 bits (109), Expect = 8e-05
Identities = 26/90 (28%), Positives = 56/90 (62%), Gaps = 3/90 (3%)
Query: 5 KKKKVTKAERLKLLQEEEER-RLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLE 63
+KKK + E+ K +EE ER R + E E R + E+E ++ E++ ++K + ++LE
Sbjct: 820 EKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELE 879
Query: 64 RR--NEELEELYLLERCFPEAEKLKQETKL 91
++ N+++EE+ LE+ + +++K++ +L
Sbjct: 880 KQKENKQVEEILRLEKEIEDLQRMKEQQEL 909
Score = 33.1 bits (74), Expect = 0.92
Identities = 21/66 (31%), Positives = 39/66 (59%), Gaps = 4/66 (6%)
Query: 291 AISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSET 350
A +E EE+ KQ+E +EEE + E E+ + E++ A++E E K ++E++ L ++
Sbjct: 813 AEKREQEEKKKQEEEEKKKREEEERERERERREAELR---AQQEEETRK-QQELEALQKS 868
Query: 351 VSAAQL 356
A+L
Sbjct: 869 QKEAEL 874
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/121 (27%), Positives = 68/121 (56%), Gaps = 10/121 (8%)
Query: 262 ALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQERGSHLIQEEEI-----K 316
A+ P+ +PSKE + V+D + +E K E+++K +E H IQ E++ K
Sbjct: 72 AVPPLPSPSKE-EEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSK 130
Query: 317 VEEEQGDIEVKMSSAEEES-EAIKC-EREMKVLSETVSAAQLLLV--ENSSEKPDFFEDN 372
++E+Q D++ ++ A +E+ EA++ ER M+ +++T A ++ + E + E+ + +
Sbjct: 131 MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQE 190
Query: 373 V 373
V
Sbjct: 191 V 191
Score = 33.1 bits (74), Expect = 0.92
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 22/124 (17%)
Query: 6 KKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERR 65
+ ++T AE L L E+ E +KE +++ LK + EE+ ++ EK AKD + R
Sbjct: 798 RAEITDAEGLGLKLEDRETVIKELKKS-LKIKGEELSEANVRLSLLEKKLDSAAKDADER 856
Query: 66 NEE----LEELYLL----ERCFP-------------EAEKLKQETKLLSQWKHYIQCDGS 104
E+ LEE L E+ F EAEK + + +L SQ K I+
Sbjct: 857 IEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRG 916
Query: 105 PDPS 108
P PS
Sbjct: 917 PPPS 920
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/121 (27%), Positives = 68/121 (56%), Gaps = 10/121 (8%)
Query: 262 ALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQERGSHLIQEEEI-----K 316
A+ P+ +PSKE + V+D + +E K E+++K +E H IQ E++ K
Sbjct: 186 AVPPLPSPSKE-EEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSK 244
Query: 317 VEEEQGDIEVKMSSAEEES-EAIKC-EREMKVLSETVSAAQLLLV--ENSSEKPDFFEDN 372
++E+Q D++ ++ A +E+ EA++ ER M+ +++T A ++ + E + E+ + +
Sbjct: 245 MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQE 304
Query: 373 V 373
V
Sbjct: 305 V 305
Score = 33.1 bits (74), Expect = 0.92
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 22/124 (17%)
Query: 6 KKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERR 65
+ ++T AE L L E+ E +KE +++ LK + EE+ ++ EK AKD + R
Sbjct: 912 RAEITDAEGLGLKLEDRETVIKELKKS-LKIKGEELSEANVRLSLLEKKLDSAAKDADER 970
Query: 66 NEE----LEELYLL----ERCFP-------------EAEKLKQETKLLSQWKHYIQCDGS 104
E+ LEE L E+ F EAEK + + +L SQ K I+
Sbjct: 971 IEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRG 1030
Query: 105 PDPS 108
P PS
Sbjct: 1031 PPPS 1034
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/121 (27%), Positives = 68/121 (56%), Gaps = 10/121 (8%)
Query: 262 ALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQERGSHLIQEEEI-----K 316
A+ P+ +PSKE + V+D + +E K E+++K +E H IQ E++ K
Sbjct: 72 AVPPLPSPSKE-EEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSK 130
Query: 317 VEEEQGDIEVKMSSAEEES-EAIKC-EREMKVLSETVSAAQLLLV--ENSSEKPDFFEDN 372
++E+Q D++ ++ A +E+ EA++ ER M+ +++T A ++ + E + E+ + +
Sbjct: 131 MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQE 190
Query: 373 V 373
V
Sbjct: 191 V 191
Score = 33.1 bits (74), Expect = 0.92
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 22/124 (17%)
Query: 6 KKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERR 65
+ ++T AE L L E+ E +KE +++ LK + EE+ ++ EK AKD + R
Sbjct: 798 RAEITDAEGLGLKLEDRETVIKELKKS-LKIKGEELSEANVRLSLLEKKLDSAAKDADER 856
Query: 66 NEE----LEELYLL----ERCFP-------------EAEKLKQETKLLSQWKHYIQCDGS 104
E+ LEE L E+ F EAEK + + +L SQ K I+
Sbjct: 857 IEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRG 916
Query: 105 PDPS 108
P PS
Sbjct: 917 PPPS 920
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/121 (27%), Positives = 68/121 (56%), Gaps = 10/121 (8%)
Query: 262 ALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQERGSHLIQEEEI-----K 316
A+ P+ +PSKE + V+D + +E K E+++K +E H IQ E++ K
Sbjct: 206 AVPPLPSPSKE-EEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSK 264
Query: 317 VEEEQGDIEVKMSSAEEES-EAIKC-EREMKVLSETVSAAQLLLV--ENSSEKPDFFEDN 372
++E+Q D++ ++ A +E+ EA++ ER M+ +++T A ++ + E + E+ + +
Sbjct: 265 MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQE 324
Query: 373 V 373
V
Sbjct: 325 V 325
Score = 33.1 bits (74), Expect = 0.92
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 22/124 (17%)
Query: 6 KKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERR 65
+ ++T AE L L E+ E +KE +++ LK + EE+ ++ EK AKD + R
Sbjct: 932 RAEITDAEGLGLKLEDRETVIKELKKS-LKIKGEELSEANVRLSLLEKKLDSAAKDADER 990
Query: 66 NEE----LEELYLL----ERCFP-------------EAEKLKQETKLLSQWKHYIQCDGS 104
E+ LEE L E+ F EAEK + + +L SQ K I+
Sbjct: 991 IEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRG 1050
Query: 105 PDPS 108
P PS
Sbjct: 1051 PPPS 1054
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 46.2 bits (108), Expect = 1e-04
Identities = 79/366 (21%), Positives = 144/366 (39%), Gaps = 52/366 (14%)
Query: 5 KKKKVTKAERLKLLQEE-----------EERRLKEEEEARLKYE------KEEMERLEIQ 47
KK++ +AERL+ +QEE E+RR KEEEE R+K E +EE ER + +
Sbjct: 916 KKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKRE 975
Query: 48 RIEKEKWHRLEAKDLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDP 107
EK +EA+ ++ EE ++ +LE+ E + ++ I + D
Sbjct: 976 DDEKRIQAEVEAQLARQKEEESQQQAVLEQ---ERRDRELALRIAQSEAELISDEAQADL 1032
Query: 108 SVAQEMNTFISLWKEKTNETFEEVIEKSKVVL---NLIEKLKFILLETPPCDLQDK-NII 163
++ + T + E+ + E + + VL K+ L + +L+D N
Sbjct: 1033 ALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTS 1092
Query: 164 QYQESILQLQELLHLKFGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNP 223
E + +E H + V K + + K + D + ++ + ++NP
Sbjct: 1093 CDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQ-RAPKSVTDYDFAPFLNNSPQQNP 1151
Query: 224 ------RHRSVRFSETQIGFEIPRILATSDI------AVRLLHTHYD-----HVSALHPV 266
R R + + Q F IP I + H+D LHP
Sbjct: 1152 AAQIPARQREIEMNRQQRFFRIPFIRPADQYKDPQSKKKGWWYAHFDGPWIARQMELHPD 1211
Query: 267 STPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEV 326
P + KDD++ E +EE ++RG+ ++ + ++ E G I+
Sbjct: 1212 KPP------ILLVAGKDDMEMCE----LNLEETGLTRKRGAEILPRQFEEIWERCGGIQY 1261
Query: 327 KMSSAE 332
++ E
Sbjct: 1262 LQNAIE 1267
Score = 33.5 bits (75), Expect = 0.71
Identities = 26/73 (35%), Positives = 41/73 (56%), Gaps = 5/73 (6%)
Query: 16 KLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELYLL 75
+LL ++++ +EEE RL+ +EEME+ +R E EK R K+ E R +LE
Sbjct: 908 ELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRR---KEEEERRMKLE--MEA 962
Query: 76 ERCFPEAEKLKQE 88
+R E E+ K+E
Sbjct: 963 KRKQEEEERKKRE 975
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 46.2 bits (108), Expect = 1e-04
Identities = 93/396 (23%), Positives = 177/396 (44%), Gaps = 62/396 (15%)
Query: 14 RLKLLQEEEERRLKEEEEARLKYEKEEMER----LEIQRIEKE----KWHRLEAKDLERR 65
RL+L+++E + R EE+ + E E + R +E++ + KE K K+L+R
Sbjct: 1192 RLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRL 1251
Query: 66 NEEL-EELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKT 124
EE+ ++ L+ERC E +LK+E + L K +Q V QE+ F ++
Sbjct: 1252 REEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQ-----TKEVVQEILQF-----QED 1301
Query: 125 NETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFGVAT 184
+T EEV + E+ K + LE Q++ I + +E + +++E + + V
Sbjct: 1302 PQTKEEVASLRAKLSE--EQKKQVDLERERAS-QEEQIARKEEELSRVKERVVQQEVVRY 1358
Query: 185 EI---LLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPR 241
E L +AS A+ + ++ K + A L++ R R+ + + E+ R
Sbjct: 1359 EEEPGLRAEASAFAESIDVELRQIDK-------LRAELRRLQRRRTELERQLE---ELER 1408
Query: 242 ILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELV--KDDVKNVEKAISK-EVEE 298
A R + ++AL ++E + ++V +D + E A+ + ++EE
Sbjct: 1409 ERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEE 1468
Query: 299 ESKQQE----------RGSHLIQEEEIK--------VEEEQGDIEVKM----SSAEEESE 336
E +++ R +++ E+K V+ E+GD E ++ SS EEES
Sbjct: 1469 EQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESR 1528
Query: 337 AIKCEREMKVLSETVSAAQLLLVENSSEKP-DFFED 371
+ K E +++V ++L + S K DF +
Sbjct: 1529 S-KRELDVEVSRLEARLSELEFHNSKSSKELDFLRE 1563
Score = 35.4 bits (80), Expect = 0.19
Identities = 78/403 (19%), Positives = 171/403 (42%), Gaps = 73/403 (18%)
Query: 6 KKKVTKAERLKL------------LQEEEERR--LKEEEEARLKYEKEEMERLEIQR--- 48
++KVT+ E +KL LQE+ +R+ L+E++E L + +++++RLE +R
Sbjct: 1049 QEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMA 1108
Query: 49 -----------IEKEKWHRLEAKDLERRNE---------ELEELYLLERCFPEAEKLKQE 88
+EK+ E DL R+ E + E+ LL + + E +
Sbjct: 1109 EGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEE---EN 1165
Query: 89 TKLLSQWKHYIQCDGSPDPSVAQEM-NTFISL-WKEKTNETFEEVIEKSKVVLNLIEKLK 146
K++ Q K ++ PDP E+ N + L +E+ EE + + L + +
Sbjct: 1166 AKVVVQEK--VREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRR-- 1221
Query: 147 FILLETPPCDLQD--KNIIQYQESILQLQELLHLKFGVATEILLKQASTLADLDSGNMEK 204
P ++++ K +I+Y+ +EL L+ + + L + L +
Sbjct: 1222 ----RGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQ 1277
Query: 205 VIKDENVTLYVWANLKKNPRHRSVRFSE-TQIGFEIPRILA-TSDIAVRLLHTHYDHVSA 262
+KD + K ++F E Q E+ + A S+ + + + S
Sbjct: 1278 ALKDTKPQVQT-----KEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQ 1332
Query: 263 LHPVSTPSKEYTSAVTELVKDDVKNVEK---------AISKEVEEESKQQERGSHLIQEE 313
++ +E + +V+ +V E+ A ++ ++ E +Q ++ ++ E
Sbjct: 1333 EEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDK----LRAE 1388
Query: 314 EIKVEEEQGDIEVKMSSAEEESEAIK-CEREMKVLSETVSAAQ 355
+++ + ++E ++ E E +A + ERE++ L + ++A +
Sbjct: 1389 LRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALE 1431
Score = 35.0 bits (79), Expect = 0.24
Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 19/143 (13%)
Query: 5 KKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAK---- 60
++KK ER + QEE+ R KEEE +R+ KE + + E+ R E+E R EA
Sbjct: 1318 EQKKQVDLERERASQEEQIAR-KEEELSRV---KERVVQQEVVRYEEEPGLRAEASAFAE 1373
Query: 61 ----DLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTF 116
+L + ++ EL L+R E E+ +E + Q + + + Q +
Sbjct: 1374 SIDVELRQIDKLRAELRRLQRRRTELERQLEELERERQARREAERE-------VQRLQQR 1426
Query: 117 ISLWKEKTNETFEEVIEKSKVVL 139
++ +++ E E+V KVVL
Sbjct: 1427 LAALEQEEAEAREKVTHTQKVVL 1449
Score = 34.7 bits (78), Expect = 0.32
Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 12/93 (12%)
Query: 6 KKKVTKAERLKLLQ---EEEERRLKE--EEEARLKYEKE-EMERLEIQRIEKEKWHRLEA 59
K+KV +E +++ + E+E +RLK EEE+R K E + E+ RLE + E E + +
Sbjct: 1496 KEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSS 1555
Query: 60 KDLERRNEELEELYLLERCFPEAEKLKQETKLL 92
K+L+ EE +L L E + L+ ET+ L
Sbjct: 1556 KELDFLREENHKLQL------ERQNLQLETRRL 1582
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,027,979
Number of Sequences: 37866
Number of extensions: 1281704
Number of successful extensions: 20267
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 236
Number of HSP's successfully gapped in prelim test: 567
Number of HSP's that attempted gapping in prelim test: 10025
Number of HSP's gapped (non-prelim): 6637
length of query: 716
length of database: 18,247,518
effective HSP length: 109
effective length of query: 607
effective length of database: 14,120,124
effective search space: 8570915268
effective search space used: 8570915268
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.