Search of human proteins with 109134351

Search of human proteins with 109134351

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109134351 zinc finger and BTB domain containing 44 [Homo
sapiens]
         (453 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109134351 zinc finger and BTB domain containing 44 [Homo sapi...   911   0.0  
gi|32469511 B-cell CLL/lymphoma 6, member B (zinc finger protein...   122   7e-28
gi|157694499 zinc finger and BTB domain containing 10 isoform a ...   114   2e-25
gi|8923885 myoneurin [Homo sapiens]                                   112   5e-25
gi|47679080 zinc finger and BTB domain containing 46 [Homo sapiens]   112   5e-25
gi|157694497 zinc finger and BTB domain containing 10 isoform b ...   112   5e-25
gi|167234429 zinc finger and BTB domain containing 17 [Homo sapi...   111   1e-24
gi|223972645 zinc finger protein 509 [Homo sapiens]                   107   3e-23
gi|45827690 BTB and CNC homology 1 transcription factor isoform ...   103   3e-22
gi|4502353 BTB and CNC homology 1 transcription factor isoform a...   103   3e-22
gi|224591419 zinc finger and BTB domain containing 8B [Homo sapi...   100   2e-21
gi|19923354 zinc finger protein 238 isoform 2 [Homo sapiens]          100   3e-21
gi|45439302 zinc finger protein 238 isoform 1 [Homo sapiens]          100   3e-21
gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]    100   5e-21
gi|149944640 zinc finger and BTB domain containing 34 [Homo sapi...    97   4e-20
gi|8922854 kelch-like 26 [Homo sapiens]                                96   5e-20
gi|170650685 zinc finger and BTB domain containing 37 isoform a ...    96   7e-20
gi|11056006 kelch-like 12 [Homo sapiens]                               95   1e-19
gi|7662074 zinc finger and BTB domain containing 5 [Homo sapiens]      94   3e-19
gi|13540490 BTB and CNC homology 1, basic leucine zipper transcr...    93   6e-19
gi|156616301 kelch-like 32 [Homo sapiens]                              92   1e-18
gi|7705375 zinc finger and BTB domain containing 7A [Homo sapiens]     91   2e-18
gi|5730122 zinc finger and BTB domain containing 6 [Homo sapiens]      91   2e-18
gi|5174473 intracisternal A particle-promoted polypeptide isofor...    89   8e-18
gi|94721342 zinc finger and BTB domain containing 8A [Homo sapiens]    89   8e-18
gi|223890235 intracisternal A particle-promoted polypeptide isof...    89   8e-18
gi|45643138 kelch-like 13 [Homo sapiens]                               83   4e-16
gi|24308181 kelch-like 9 [Homo sapiens]                                83   6e-16
gi|14670366 POZ (BTB) and AT hook containing zinc finger 1 long ...    82   1e-15
gi|14670364 POZ (BTB) and AT hook containing zinc finger 1 short...    82   1e-15

>gi|109134351 zinc finger and BTB domain containing 44 [Homo
           sapiens]
          Length = 453

 Score =  911 bits (2354), Expect = 0.0
 Identities = 453/453 (100%), Positives = 453/453 (100%)

Query: 1   MGVKTFTHSSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKL 60
           MGVKTFTHSSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKL
Sbjct: 1   MGVKTFTHSSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKL 60

Query: 61  VGQAEDENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTC 120
           VGQAEDENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTC
Sbjct: 61  VGQAEDENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTC 120

Query: 121 SEFMKSSILWNTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRES 180
           SEFMKSSILWNTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRES
Sbjct: 121 SEFMKSSILWNTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRES 180

Query: 181 RRKRKSYIVMSPESPVKCGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFPFGIDRRI 240
           RRKRKSYIVMSPESPVKCGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFPFGIDRRI
Sbjct: 181 RRKRKSYIVMSPESPVKCGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFPFGIDRRI 240

Query: 241 QPEKVKQAENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVH 300
           QPEKVKQAENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVH
Sbjct: 241 QPEKVKQAENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVH 300

Query: 301 EEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSSTN 360
           EEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSSTN
Sbjct: 301 EEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSSTN 360

Query: 361 APPDDDDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLI 420
           APPDDDDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLI
Sbjct: 361 APPDDDDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLI 420

Query: 421 HSGIKPFQCDRCGKKFTRAYSLKMHRLKHEVIS 453
           HSGIKPFQCDRCGKKFTRAYSLKMHRLKHEVIS
Sbjct: 421 HSGIKPFQCDRCGKKFTRAYSLKMHRLKHEVIS 453


>gi|32469511 B-cell CLL/lymphoma 6, member B (zinc finger protein)
           [Homo sapiens]
          Length = 480

 Score =  122 bits (306), Expect = 7e-28
 Identities = 129/497 (25%), Positives = 203/497 (40%), Gaps = 90/497 (18%)

Query: 2   GVKTFTHSSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLV 61
           G   +    + HS ++LG LN LR  G   D+T+ V  +  RAHK VL ACS FF +   
Sbjct: 9   GALGYVREFTRHSSDVLGNLNELRLRGILTDVTLLVGGQPLRAHKAVLIACSGFFYSIFR 68

Query: 62  GQAEDENKNVLDLHH-VTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTC 120
           G+A     +VL L       GF PLL++ YT+ L ++      VLAAA+Y+QM  V   C
Sbjct: 69  GRA-GVGVDVLSLPGGPEARGFAPLLDFMYTSRLRLSPATAPAVLAAATYLQMEHVVQAC 127

Query: 121 SEFMKSSILW------------NTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECS 168
             F+++S                TP + P  G     E + +    SR  S  P S    
Sbjct: 128 HRFIQASYEPLGISLRPLEAEPPTPPTAPPPGSPRRSEGHPDPPTESRSCSQGPPSPAS- 186

Query: 169 VVERTIPVCRESRRKRKSYIVMS-------------------PESPVKCGTQTSSPQVLN 209
                 P  +    K+  YIV++                   P++ +  G + SS    +
Sbjct: 187 ------PDPKACNWKKYKYIVLNSQASQAGSLVGERSSGQPCPQARLPSGDEASSSSSSS 240

Query: 210 SSASYSE-------NRNQPVDSSLAF----PWTFPFGIDRRIQPEKVKQAENTRTLELPG 258
           SS+S  E       +R  P  +++ F    P + P+ +  + Q      +E  R L  PG
Sbjct: 241 SSSSSEEGPIPGPQSRLSPTAATVQFKCGAPASTPYLLTSQAQDTSGSPSERARPL--PG 298

Query: 259 PSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVHEEVSQPVSASQSSLSDQQ 318
                   +++ +C++ +      +  D  V  +   D+    ++ +     + +L+  +
Sbjct: 299 --------SEFFSCQNCEAVAGCSSGLDSLVPGDE--DKPYKCQLCRSSFRYKGNLASHR 348

Query: 319 TVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSSTNAPPDDDDRLENVQYPYQL 378
           TV   E+        P   SI     G     P    T S         R+ + + PY+ 
Sbjct: 349 TVHTGEK--------PYHCSIC----GARFNRPANLKTHS---------RIHSGEKPYKC 387

Query: 379 YIAPS-----TSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCG 433
               S              +  ++P+ CPTCG RF  +Q LK H+ IH+G KP+ CD CG
Sbjct: 388 ETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVRIHTGEKPYHCDPCG 447

Query: 434 KKFTRAYSLKMH-RLKH 449
             F     L++H R KH
Sbjct: 448 LHFRHKSQLRLHLRQKH 464


>gi|157694499 zinc finger and BTB domain containing 10 isoform a
           [Homo sapiens]
          Length = 871

 Score =  114 bits (285), Expect = 2e-25
 Identities = 106/455 (23%), Positives = 182/455 (40%), Gaps = 36/455 (7%)

Query: 9   SSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLV--GQAED 66
           + +S+  ++L +LN  R  G  CD++I V  KIF+AHK +L A S FF+T      +   
Sbjct: 342 NENSYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESP 401

Query: 67  ENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKS 126
              N   L    V GF  +L++ Y+  L + ++N I+V+  ASY+QM  V  TC  F+K 
Sbjct: 402 NQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKD 461

Query: 127 SILWNTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCR-ESRRKRK 185
           ++  +  +  PE  +     + +N    +RDG  S    + +    T  +    S  K +
Sbjct: 462 ALNISIKSEAPESVV----VDYNNRKPVNRDGLSSSRDQKIASFWATRNLTNLASNVKIE 517

Query: 186 SYIVMSPESPVKCGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFPFGIDRRIQPEKV 245
           +      E  ++      S  V + S   +EN ++       +      GI    +  + 
Sbjct: 518 NDGCNVDEGQIENYQMNDSSWVQDGSPEMAENESEGQTKVFIWNNMGSQGIQETGKTRRK 577

Query: 246 KQAENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVE------RLSDEEV 299
            Q        +P  +ET     +   C   +  +    E  + +K E       LS  + 
Sbjct: 578 NQTTKRFIYNIPPNNET-----NLEDCSVMQPPVAYPEENTLLIKEEPDLDGALLSGPDG 632

Query: 300 HEEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSST 359
              V+  + A   +  D      S   +  L+  P +     +  G S          ++
Sbjct: 633 DRNVNANLLAEAGTSQDGGDAGTSHDFKYGLMPGPSNDFKYGLIPGTSNDFKYGLIPGAS 692

Query: 360 NAPPDDDDRLENVQYPYQLYIAPSTSSTERPSPNGPD----RPFQCPTCGVRFTRIQNLK 415
           N               ++  + P +   +    NG         +CP C       + LK
Sbjct: 693 N--------------DFKYGLLPESWPKQETWENGESSLIMNKLKCPHCSYVAKYRRTLK 738

Query: 416 QHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKHE 450
           +H+LIH+G++ F CD CGK FTR   +K H L H+
Sbjct: 739 RHLLIHTGVRSFSCDICGKLFTRREHVKRHSLVHK 773


>gi|8923885 myoneurin [Homo sapiens]
          Length = 610

 Score =  112 bits (281), Expect = 5e-25
 Identities = 113/456 (24%), Positives = 190/456 (41%), Gaps = 39/456 (8%)

Query: 11  SSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENKN 70
           S H + +L +LN  R  G  CD TI + +  F+AH+ VLA+ S++F    + ++  EN  
Sbjct: 4   SHHCEHLLERLNKQREAGFLCDCTIVIGEFQFKAHRNVLASFSEYFGA--IYRSTSENNV 61

Query: 71  VLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILW 130
            LD   V   GF  LLE+ YT TL++++ N+ ++  AA Y+++  V + C   M+     
Sbjct: 62  FLDQSQVKADGFQKLLEFIYTGTLNLDSWNVKEIHQAADYLKVEEVVTKCKIKMEDFAFI 121

Query: 131 NTPNSQPEKGLDAGQE-NNSNCNFTSRDGSISPVSSECSVVERTIP-----VCRESRRKR 184
             P+S     +    E N   C  T RD +    S   + + +  P       + S+ K+
Sbjct: 122 ANPSSTEISSITGNIELNQQTCLLTLRDYNNREKSEVSTDLIQANPKQGALAKKSSQTKK 181

Query: 185 KSYIVMSPESPVKCGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFPFGIDRRIQPEK 244
           K     SP++      Q  S  + N+S     + N+     L  P             E+
Sbjct: 182 KKKAFNSPKTGQNKTVQYPSDILENASVELFLDANK-----LPTPVV-----------EQ 225

Query: 245 VKQAENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVHEEVS 304
           V Q  +   LEL    E      D V   + K      ++ +  +K   +S+      V 
Sbjct: 226 VAQINDNSELELTSVVENTFPAQDIVHTVTVKRKRG-KSQPNCALKEHSMSN---IASVK 281

Query: 305 QPVSASQSSLS-DQQTVPGSEQVQEDLLISPQSSSIG---SVDEGVSEGLPTLQSTSSTN 360
            P  A  S    DQ+             +  ++SS+     + +GV   +  L   + T 
Sbjct: 282 SPYEAENSGEELDQRYSKAKPMCNTCGKVFSEASSLRRHMRIHKGVKPYVCHLCGKAFTQ 341

Query: 361 APP-DDDDRLENVQYPYQLYIAPSTSSTE------RPSPNGPDRPFQCPTCGVRFTRIQN 413
                   R    + PY+  +     + +          +G ++P++C  C ++F    N
Sbjct: 342 CNQLKTHVRTHTGEKPYKCELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVCNLQFATSSN 401

Query: 414 LKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
           LK H   HSG KP+ CDRCG++F +A +L  H  +H
Sbjct: 402 LKIHARKHSGEKPYVCDRCGQRFAQASTLTYHVRRH 437



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 26/72 (36%), Positives = 37/72 (51%)

Query: 378 LYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFT 437
           L  A S++       +  ++P+ C  CG RF +   L  H+  H+G KP+ CD CGK F 
Sbjct: 394 LQFATSSNLKIHARKHSGEKPYVCDRCGQRFAQASTLTYHVRRHTGEKPYVCDTCGKAFA 453

Query: 438 RAYSLKMHRLKH 449
            + SL  H  KH
Sbjct: 454 VSSSLITHSRKH 465



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 22/68 (32%), Positives = 34/68 (50%)

Query: 381 APSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAY 440
           A S+S       +  ++P+ C  CG  F     L +H   H+G +PF C+ CG  +T   
Sbjct: 453 AVSSSLITHSRKHTGEKPYICGICGKSFISSGELNKHFRSHTGERPFICELCGNSYTDIK 512

Query: 441 SLKMHRLK 448
           +LK H+ K
Sbjct: 513 NLKKHKTK 520



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 20/54 (37%), Positives = 27/54 (50%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
           ++P+ C TCG  F    +L  H   H+G KP+ C  CGK F  +  L  H   H
Sbjct: 440 EKPYVCDTCGKAFAVSSSLITHSRKHTGEKPYICGICGKSFISSGELNKHFRSH 493


>gi|47679080 zinc finger and BTB domain containing 46 [Homo sapiens]
          Length = 589

 Score =  112 bits (281), Expect = 5e-25
 Identities = 119/485 (24%), Positives = 198/485 (40%), Gaps = 73/485 (15%)

Query: 11  SSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVG-QAEDENK 69
           +SH + +L +LN  R  G  CD+ + V+ K+F+AHK VL   S +F+T     Q   E  
Sbjct: 11  TSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSEQA 70

Query: 70  NVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSS-- 127
            V  L  VT  GF  ++++ Y+A L++ + N+I+V++AAS++QM  +   C +F+K++  
Sbjct: 71  TVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALD 130

Query: 128 ILWNTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRKRKSY 187
           I   +  S      + G  ++S     S +  IS V +  S+                S 
Sbjct: 131 ISIKSDASDELAEFEIGASSSS-----STEALISAVMAGRSI----------------SP 169

Query: 188 IVMSPESPVKCGTQTSSPQVLNSSASYSENRNQP-------VDSSLAFPWTFPFGIDRRI 240
            +    SP      ++     +  +SY +   +P       V S   +P    +G   RI
Sbjct: 170 WLARRTSPADSSGDSAIASCHDGGSSYGKEDQEPKADGPDDVSSQPLWPGDVGYG-PLRI 228

Query: 241 QPEKVKQAENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVH 300
           + E+V  ++   + ELP  ++ G     +    +     P G  ++ + K       +  
Sbjct: 229 KEEQVSPSQYGGS-ELPS-AKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQV 286

Query: 301 EEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSS---------IGSVDEGVSEGLP 351
           E+ S+  S   S L        S     DL ++  SSS            V+EG+  G  
Sbjct: 287 EDDSRASSPVPSFLPTSGWPFSSRDSNADLSVTEASSSDSRGERAELYAQVEEGLLGGEA 346

Query: 352 TLQSTSSTNAPPDDDDRLENVQYPYQLYIAPSTSS---TERPSPNGPD------------ 396
           +      T   P+ DD L        L  A  + +   + +    G D            
Sbjct: 347 SYLGPPLT---PEKDDALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGA 403

Query: 397 ------------RPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKM 444
                       + F+CP C         LK+HM  H+G +P+ C+ CGKKFTR   +K 
Sbjct: 404 HSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKR 463

Query: 445 HRLKH 449
           H L H
Sbjct: 464 HTLVH 468



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 19/47 (40%), Positives = 30/47 (63%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSL 442
           +RP+ C  CG +FTR +++K+H L+HS  K + C  C + F  A S+
Sbjct: 443 ERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASV 489


>gi|157694497 zinc finger and BTB domain containing 10 isoform b
           [Homo sapiens]
          Length = 847

 Score =  112 bits (281), Expect = 5e-25
 Identities = 108/449 (24%), Positives = 180/449 (40%), Gaps = 48/449 (10%)

Query: 9   SSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLV--GQAED 66
           + +S+  ++L +LN  R  G  CD++I V  KIF+AHK +L A S FF+T      +   
Sbjct: 342 NENSYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESP 401

Query: 67  ENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKS 126
              N   L    V GF  +L++ Y+  L + ++N I+V+  ASY+QM  V  TC  F+K 
Sbjct: 402 NQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKD 461

Query: 127 SILWNTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCR-ESRRKRK 185
           ++  +  +  PE  +     + +N    +RDG  S    + +    T  +    S  K +
Sbjct: 462 ALNISIKSEAPESVV----VDYNNRKPVNRDGLSSSRDQKIASFWATRNLTNLASNVKIE 517

Query: 186 SYIVMSPESPVKCGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFPFGIDRRIQPEKV 245
           +      E  ++      S  V + S   +EN ++       +      GI    +  + 
Sbjct: 518 NDGCNVDEGQIENYQMNDSSWVQDGSPEMAENESEGQTKVFIWNNMGSQGIQETGKTRRK 577

Query: 246 KQAENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVHEEVSQ 305
            Q        +P  +ET     +   C   +  +    E  + +K E   D  +   +S 
Sbjct: 578 NQTTKRFIYNIPPNNET-----NLEDCSVMQPPVAYPEENTLLIKEEPDLDGAL---LSG 629

Query: 306 PVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSSTNAPPDD 365
           P               G   V  +LL    +S  G  D G S          ++N     
Sbjct: 630 P--------------DGDRNVNANLLAEAGTSQDGG-DAGTSHDFKYGLMPGASN----- 669

Query: 366 DDRLENVQYPYQLYIAPSTSSTERPSPNGPD----RPFQCPTCGVRFTRIQNLKQHMLIH 421
                     ++  + P +   +    NG         +CP C       + LK+H+LIH
Sbjct: 670 ---------DFKYGLLPESWPKQETWENGESSLIMNKLKCPHCSYVAKYRRTLKRHLLIH 720

Query: 422 SGIKPFQCDRCGKKFTRAYSLKMHRLKHE 450
           +G++ F CD CGK FTR   +K H L H+
Sbjct: 721 TGVRSFSCDICGKLFTRREHVKRHSLVHK 749


>gi|167234429 zinc finger and BTB domain containing 17 [Homo
           sapiens]
          Length = 803

 Score =  111 bits (278), Expect = 1e-24
 Identities = 108/437 (24%), Positives = 167/437 (38%), Gaps = 86/437 (19%)

Query: 13  HSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENKNVL 72
           HSQ +L +LN  R  G  CD T  V    F+AHK VLAACS++F+   V Q     K+V+
Sbjct: 6   HSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLFVDQ-----KDVV 60

Query: 73  DLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWNT 132
            L      G   +LE+ YTA LS++ EN+ DVLA A+++QM  + + C   +KS      
Sbjct: 61  HLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVATFLQMQDIITAC-HALKSL----- 114

Query: 133 PNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRKRKSYIVMSP 192
             ++P                TS  G+   +++E              +R ++  +  S 
Sbjct: 115 --AEPA---------------TSPGGNAEALATEGG-----------DKRAKEEKVATST 146

Query: 193 ESPVKCGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFPFGIDRRIQPEKVKQAENTR 252
            S ++   Q      +  S    E R     S+ +       G +   Q EK        
Sbjct: 147 LSRLE---QAGRSTPIGPSRDLKEERGGQAQSAAS-------GAE---QTEKADAPREPP 193

Query: 253 TLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVHEEVSQPVSASQS 312
            +EL     +G   A+     S  +   +  E   + + E+   EE  EE + P    + 
Sbjct: 194 PVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEEQKEQEEQEEEGAGPAEVKEE 253

Query: 313 SLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSSTNAPPDDDDRLENV 372
               +      E   E+   +     +GS   G+  G                 DR E+ 
Sbjct: 254 GSQLENGEAPEENENEESAGTDSGQELGSEARGLRSG--------------TYGDRTESK 299

Query: 373 QYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRC 432
            Y   ++                    +C  CG  FT   N K+H+ IH+G KPF C  C
Sbjct: 300 AYGSVIH--------------------KCEDCGKEFTHTGNFKRHIRIHTGEKPFSCREC 339

Query: 433 GKKFTRAYSLKMHRLKH 449
            K F+   + K H   H
Sbjct: 340 SKAFSDPAACKAHEKTH 356



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 24/52 (46%), Positives = 32/52 (61%)

Query: 399 FQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKHE 450
           ++C  CG  FT   NLK+H L+HSG KP+QCD CG+ F+   S   H   H+
Sbjct: 390 YRCEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHD 441



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 20/49 (40%), Positives = 32/49 (65%)

Query: 397 RPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMH 445
           RP +C  C   F  + +L +H++IH+G KP+ CD+CG+ F R  +L+ H
Sbjct: 584 RPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSH 632



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 23/57 (40%), Positives = 35/57 (61%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKHEVI 452
           ++P QC  CG  FT+  +L  H+  H+G KP+ C+RCGK+F ++  L  H   H+ I
Sbjct: 527 EKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNI 583



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 24/66 (36%), Positives = 35/66 (53%)

Query: 384 TSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLK 443
           TS       +  D+  +CP C  +F ++ NLK H+ IH    P +C  CGK+FT + +LK
Sbjct: 431 TSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLK 490

Query: 444 MHRLKH 449
            H   H
Sbjct: 491 RHLRIH 496



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 22/50 (44%), Positives = 31/50 (62%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMH 445
           D P +C  CG +FT   NLK+H+ IHSG KP+ C  C ++F    +L+ H
Sbjct: 471 DGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQRH 520



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 23/54 (42%), Positives = 33/54 (61%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
           ++P+ C  C  +F     L++H+ IH+G KP QC  CGK FT+A SL  H  +H
Sbjct: 499 EKPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQH 552



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 18/54 (33%), Positives = 26/54 (48%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
           ++P+ C  CG RF +   L  H+  H  I+P +C  C K F     L  H + H
Sbjct: 555 EKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIH 608



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 11/29 (37%), Positives = 18/29 (62%), Gaps = 1/29 (3%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHM-LIHSG 423
           ++P+ C  CG  F R+ NL+ H+  +H G
Sbjct: 611 EKPYLCDKCGRGFNRVDNLRSHVKTVHQG 639


>gi|223972645 zinc finger protein 509 [Homo sapiens]
          Length = 765

 Score =  107 bits (266), Expect = 3e-23
 Identities = 116/479 (24%), Positives = 201/479 (41%), Gaps = 50/479 (10%)

Query: 11  SSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENKN 70
           ++HS  +L +L+  R  G  CD  + V+   F+AHK VLAA S +FR+     +  +N +
Sbjct: 5   ATHSCHLLQQLHEQRIQGLLCDCMLVVKGVCFKAHKNVLAAFSQYFRSLFQNSSSQKN-D 63

Query: 71  VLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILW 130
           V  L    V+G   +L++ YT+ L +N +NI  +L  A  +Q+ +V S C  F+KS+ + 
Sbjct: 64  VFHLDVKNVSGIGQILDFMYTSHLDLNQDNIQVMLDTAQCLQVQNVLSLCHTFLKSATVV 123

Query: 131 NTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECS-------VVERTIPVCRESRRK 183
             P       L        +      +     +  ECS        ++ + P    S  +
Sbjct: 124 QPPGMPCNSTLSLQSTLTPDATCVISENYPPHLLQECSADAQQNKTLDESHPHASPSVNR 183

Query: 184 RKSYIVMSPESP-VKCGTQTSSP--------QVLN-SSASYSENRNQPVDSSLA-FPWTF 232
             S   +S ++P    G+ T  P        ++ N  S  Y ++   P    +   P+ F
Sbjct: 184 HHSAGEISKQAPDTSDGSCTELPFKQPNYYYKLRNFYSKQYHKHAAGPSQERVVEQPFAF 243

Query: 233 PFGID-RRIQPEKVKQAENTRTLELPG--PS--------ETGRRMADYVTCESTKTTLPL 281
               D   ++ +    + +   LE P   PS        ++        TC+     + L
Sbjct: 244 STSTDLTTVESQPCAVSHSECILESPEHLPSNFLAQPVNDSAPHPESDATCQQPVKQMRL 303

Query: 282 GTEEDVRVKVERLSDEEVHEEVSQPVSASQSSLSDQQTVPGSEQVQEDLL--ISPQSSSI 339
                ++ K+  L  ++  E+VS+P        SD       E   ++ L   S QS+  
Sbjct: 304 KKAIHLK-KLNFLKSQKYAEQVSEP-------KSDDGLTKRLESASKNTLEKASSQSAEE 355

Query: 340 GSVDEGVS-EGLPTLQSTSSTNAPPDDDDRLENVQYPYQL--------YIAPSTSSTERP 390
              +E VS E    +  T     P   +D+ + +Q   Q         +  PS     + 
Sbjct: 356 KESEEVVSCENFNCISETERPEDPAALEDQSQTLQSQRQYACELCGKPFKHPSNLELHKR 415

Query: 391 SPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
           S  G ++PF+C  CG  F++  NL+ H+  HSG KP+ C+ CGK+F  +  ++ H + H
Sbjct: 416 SHTG-EKPFECNICGKHFSQAGNLQTHLRRHSGEKPYICEICGKRFAASGDVQRHIIIH 473



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 22/54 (40%), Positives = 29/54 (53%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
           ++P  C  CG  F+   NLK+H   H+  K F CD CGK F     L  HR++H
Sbjct: 476 EKPHLCDICGRGFSNFSNLKEHKKTHTADKVFTCDECGKSFNMQRKLVKHRIRH 529



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 21/54 (38%), Positives = 33/54 (61%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
           +RP+ C  CG  F    +L++H+  H+G KP+ C+ C K FTR+  L+ H+  H
Sbjct: 532 ERPYSCSACGKCFGGSGDLRRHVRTHTGEKPYTCEICNKCFTRSAVLRRHKKMH 585



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 20/62 (32%), Positives = 30/62 (48%)

Query: 388 ERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRL 447
           E    +  D+ F C  CG  F   + L +H + H+G +P+ C  CGK F  +  L+ H  
Sbjct: 496 EHKKTHTADKVFTCDECGKSFNMQRKLVKHRIRHTGERPYSCSACGKCFGGSGDLRRHVR 555

Query: 448 KH 449
            H
Sbjct: 556 TH 557


>gi|45827690 BTB and CNC homology 1 transcription factor isoform a
           [Homo sapiens]
          Length = 736

 Score =  103 bits (257), Expect = 3e-22
 Identities = 75/245 (30%), Positives = 126/245 (51%), Gaps = 27/245 (11%)

Query: 6   FTHSSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAE 65
           F + SS HS  +L  LN  R     CD+TI V+ + FRAH+ VLAACS +F +++VGQA+
Sbjct: 9   FAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQAD 68

Query: 66  DENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMK 125
            E  N+     VTV GF PL+++AYTA L ++ EN+ +V     ++ + ++  +C +F+K
Sbjct: 69  GE-LNITLPEEVTVKGFEPLIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLK 127

Query: 126 SSILWNTPNSQ--PEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRK 183
              L +T + Q  P K     +  +S+C  T           + S++++      E    
Sbjct: 128 FKFLDSTADQQECPRK-----KCFSSHCQKT---------DLKLSLLDQRDLETDEVEEF 173

Query: 184 RKSYIVMSPESPVK--CGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFP-------- 233
            ++  V +P+  ++   G   +SP + +S++   E+     D++LA P   P        
Sbjct: 174 LENKNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKA 233

Query: 234 FGIDR 238
           FG DR
Sbjct: 234 FGTDR 238


>gi|4502353 BTB and CNC homology 1 transcription factor isoform a
           [Homo sapiens]
          Length = 736

 Score =  103 bits (257), Expect = 3e-22
 Identities = 75/245 (30%), Positives = 126/245 (51%), Gaps = 27/245 (11%)

Query: 6   FTHSSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAE 65
           F + SS HS  +L  LN  R     CD+TI V+ + FRAH+ VLAACS +F +++VGQA+
Sbjct: 9   FAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQAD 68

Query: 66  DENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMK 125
            E  N+     VTV GF PL+++AYTA L ++ EN+ +V     ++ + ++  +C +F+K
Sbjct: 69  GE-LNITLPEEVTVKGFEPLIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLK 127

Query: 126 SSILWNTPNSQ--PEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRK 183
              L +T + Q  P K     +  +S+C  T           + S++++      E    
Sbjct: 128 FKFLDSTADQQECPRK-----KCFSSHCQKT---------DLKLSLLDQRDLETDEVEEF 173

Query: 184 RKSYIVMSPESPVK--CGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFP-------- 233
            ++  V +P+  ++   G   +SP + +S++   E+     D++LA P   P        
Sbjct: 174 LENKNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKA 233

Query: 234 FGIDR 238
           FG DR
Sbjct: 234 FGTDR 238


>gi|224591419 zinc finger and BTB domain containing 8B [Homo
           sapiens]
          Length = 495

 Score =  100 bits (250), Expect = 2e-21
 Identities = 110/454 (24%), Positives = 180/454 (39%), Gaps = 60/454 (13%)

Query: 12  SHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENK-N 70
           S+  ++LG+LN  R    FCD +I V+ +IF+AH+ +L A S +FR  L+   +D  + +
Sbjct: 5   SYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHS 64

Query: 71  VLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILW 130
              L  VT   F  +L++ Y+  L +  EN+I+V++AASY+QM  V + C  +++SS L 
Sbjct: 65  TASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSS-LD 123

Query: 131 NTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCR-----ESRRKRK 185
                + E  + A     +     +   +   V SE     R    C       S  + +
Sbjct: 124 ICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSGREGTSCGTKSLVSSPAEGE 183

Query: 186 SYIVMSPESPV-KCGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFPFGIDRRIQPEK 244
             +    ESP   CG       V+  S           DS+L+ P        +RI+P+ 
Sbjct: 184 KSVECLRESPCGDCGDCHPLELVVRDSLG-----GGSADSNLSTP-------PKRIEPKV 231

Query: 245 VKQAENTRTLELPGPSETGRRMADY---VTCESTKTTLPLGTEEDVRVKVERLSDEEVHE 301
              A+           + G ++  Y   +     +  LP G   D       L+    H 
Sbjct: 232 EFDADEVEV-------DVGEQLQQYAAPLNLAHVEEALPSGQAVD-------LAYSNYH- 276

Query: 302 EVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSSTNA 361
                V     +L      P  +           S S+    EG    + ++    +   
Sbjct: 277 -----VKQFLEALLRNSAAPSKDDADHHF-----SRSLEGRPEGAGVAMSSMMDVQADWY 326

Query: 362 PPDDDDRLENVQYPYQLYIAPSTSSTERPS--------PNGPDRPFQCPTCGVRFTRIQN 413
             D  D L     P +L+  P    T +           +  +RP+ C TCG RFTR ++
Sbjct: 327 GEDSGDVL---VVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEH 383

Query: 414 LKQHML-IHSGIKPFQCDRCGKKFTRAYSLKMHR 446
           L+ H L +H   +P  C  C + FT   S  + R
Sbjct: 384 LRSHALSVHRSNRPIICKGCRRTFTSHLSQGLRR 417



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 20/53 (37%), Positives = 31/53 (58%)

Query: 395 PDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRL 447
           P +  +CP C     +   LK+H+  H+G +P+ C+ CGK+FTR   L+ H L
Sbjct: 337 PIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHAL 389


>gi|19923354 zinc finger protein 238 isoform 2 [Homo sapiens]
          Length = 522

 Score =  100 bits (249), Expect = 3e-21
 Identities = 114/469 (24%), Positives = 185/469 (39%), Gaps = 46/469 (9%)

Query: 13  HSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENKNVL 72
           HS+ +L  L+  R+ G  CD T+ V D  FRAH+ VLA+CS +F      Q +  +   L
Sbjct: 6   HSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHL 65

Query: 73  DLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWNT 132
           +   VT   F  LLE+ Y   L      I DVLAAASY+ M+ +   C + +K       
Sbjct: 66  NSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEA 125

Query: 133 PNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRKRKSYIVMSP 192
            +++ E       E+ S+C+       +  +S   S +   +P   +     K  I+ S 
Sbjct: 126 DSTKKE-------EDASSCS-----DKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSK 173

Query: 193 E----SPVKCGTQTSSPQV-LNSSASYSENRNQPVDSSLAFPWTFPFGIDRRIQPEKVKQ 247
                 P     +  S    +  +   +E        ++A P +    + +R        
Sbjct: 174 RDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDS 233

Query: 248 AENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEE--------- 298
           A+    L+L   S          +  S++  L     + V+V+ E   DE          
Sbjct: 234 ADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQ-VKVEKEASCDESDVGTNDYDM 292

Query: 299 VHEEVSQPVS------------ASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGV 346
            H  V + VS            A     S  + +   ++  +D +++P+S  +  V+ G+
Sbjct: 293 EHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERV-QVEGGM 351

Query: 347 SEGLPTLQSTSSTNAPPDDDDRLENVQY--PYQLYIAPSTSSTE----RPSPNGPDRPFQ 400
              L    S   + A       L N  +  P+ L I  ST   E    R  P        
Sbjct: 352 ESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPT 411

Query: 401 CPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
           C  CG  F+ +  LK+H   HSG KP+ C +CGK F  +++L  H + H
Sbjct: 412 CSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVH 460



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 17/50 (34%), Positives = 28/50 (56%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMH 445
           ++P+ C  CG  F    NL +H ++H+  KP  C  C ++FT++  L  H
Sbjct: 435 EKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRH 484


>gi|45439302 zinc finger protein 238 isoform 1 [Homo sapiens]
          Length = 531

 Score =  100 bits (249), Expect = 3e-21
 Identities = 114/469 (24%), Positives = 185/469 (39%), Gaps = 46/469 (9%)

Query: 13  HSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENKNVL 72
           HS+ +L  L+  R+ G  CD T+ V D  FRAH+ VLA+CS +F      Q +  +   L
Sbjct: 15  HSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHL 74

Query: 73  DLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWNT 132
           +   VT   F  LLE+ Y   L      I DVLAAASY+ M+ +   C + +K       
Sbjct: 75  NSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEA 134

Query: 133 PNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRKRKSYIVMSP 192
            +++ E       E+ S+C+       +  +S   S +   +P   +     K  I+ S 
Sbjct: 135 DSTKKE-------EDASSCS-----DKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSK 182

Query: 193 E----SPVKCGTQTSSPQV-LNSSASYSENRNQPVDSSLAFPWTFPFGIDRRIQPEKVKQ 247
                 P     +  S    +  +   +E        ++A P +    + +R        
Sbjct: 183 RDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDS 242

Query: 248 AENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEE--------- 298
           A+    L+L   S          +  S++  L     + V+V+ E   DE          
Sbjct: 243 ADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQ-VKVEKEASCDESDVGTNDYDM 301

Query: 299 VHEEVSQPVS------------ASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGV 346
            H  V + VS            A     S  + +   ++  +D +++P+S  +  V+ G+
Sbjct: 302 EHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERV-QVEGGM 360

Query: 347 SEGLPTLQSTSSTNAPPDDDDRLENVQY--PYQLYIAPSTSSTE----RPSPNGPDRPFQ 400
              L    S   + A       L N  +  P+ L I  ST   E    R  P        
Sbjct: 361 ESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPT 420

Query: 401 CPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
           C  CG  F+ +  LK+H   HSG KP+ C +CGK F  +++L  H + H
Sbjct: 421 CSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVH 469



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 17/50 (34%), Positives = 28/50 (56%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMH 445
           ++P+ C  CG  F    NL +H ++H+  KP  C  C ++FT++  L  H
Sbjct: 444 EKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRH 493


>gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]
          Length = 574

 Score = 99.8 bits (247), Expect = 5e-21
 Identities = 108/480 (22%), Positives = 184/480 (38%), Gaps = 64/480 (13%)

Query: 13  HSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENKNVL 72
           HSQ++L  L   R+ G  CD T+ V    F AH+ VLA+CS FF+     + E + ++++
Sbjct: 56  HSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQL-FYKERELDKRDLV 114

Query: 73  DLHH--VTVTGFIPLLEYAYTATLSINTEN-IIDVLAAASYMQMFSVASTCSEFMKSSIL 129
            +H+  VT   F  LL++ Y   L++  +  + DVLAAASY+ M  +   C   +++  L
Sbjct: 115 CIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQARAL 174

Query: 130 WNTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRKRKSYIV 189
               +++ E+  ++   +    + TSR    S  S+E S            + + K    
Sbjct: 175 AEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETS--------GHWGKGEWKGSAA 226

Query: 190 MSP------ESPVKCGTQTSSPQVLNSSASYSENRNQPV-DSSLAFPWT---------FP 233
            SP      E P+  G  T+ P  +   A +    + PV D SLA P +         F 
Sbjct: 227 PSPTVRPPDEPPMSSGADTTQPG-MEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFS 285

Query: 234 FGIDRRIQPEKVKQAENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVER 293
            GI                +L +  P + G  +  +    S  T+ P      V  +   
Sbjct: 286 SGISAVSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQAPA 345

Query: 294 LSDEEVHEEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTL 353
            ++ E+ +     V      +SD++T    EQ Q      P   ++        E     
Sbjct: 346 PAEAELVQ-----VKVEAIVISDEETDVSDEQPQGPERAFPSGGAVYGAQPSQPEAFEDP 400

Query: 354 QSTSSTNAPPDDDDRLENVQYPYQLYIAPSTSSTER-------PSPNGPDRPF------- 399
            +       P D     +   PY  ++ P      R       P+P     P        
Sbjct: 401 GAAGLEEVGPSDHFLPTDPHLPY--HLLPGAGQYHRGLVTSPLPAPASLHEPLYLSSEYE 458

Query: 400 --------------QCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMH 445
                          C TCG  F+    L++H  +H+  +P++C  C + +T++  L  H
Sbjct: 459 AAPGSFGVFTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRH 518


>gi|149944640 zinc finger and BTB domain containing 34 [Homo
           sapiens]
          Length = 500

 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 113/459 (24%), Positives = 174/459 (37%), Gaps = 72/459 (15%)

Query: 13  HSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRT-KLVGQAEDENKNV 71
           +S  +L +LN LR  G  CDI + +Q + FRAHK VLAA S +FR    +      + +V
Sbjct: 14  YSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISV 73

Query: 72  LDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWN 131
           +   +V    F  LL + YT  +S+  ++++  L AAS++QM  V   C++ ++S  + +
Sbjct: 74  IKNPNV----FEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILES--IHS 127

Query: 132 TPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRKRKS---YI 188
             +      +  G E N      SR+G +   S   + VE + P C + R+   S    +
Sbjct: 128 KISVGDVDSVTVGAEENPE----SRNG-VKDSSFFANPVEISPPYCSQGRQPTASSDLRM 182

Query: 189 VMSPESPVKCGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFPFGIDRRIQPEKVKQA 248
             +P   ++   Q        SS S SE                                
Sbjct: 183 ETTPSKALRSRLQEEGHSDRGSSGSVSEYE------------------------------ 212

Query: 249 ENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKV---ERLSDEEVHEE--- 302
                +++ G  E G    D +  ES  T + +  E+  R        L D+  H E   
Sbjct: 213 -----IQIEGDHEQG----DLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVD 263

Query: 303 --------VSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQ 354
                   V    S  Q + S  Q       V E       SS   S+      G    +
Sbjct: 264 GEQVVAVNVGSYGSVLQHAYSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQK 323

Query: 355 STSSTNAPPDDDDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQ----CPTCGVRFTR 410
              S +   D    ++       +      SS    S  G   P+     C  CG  F +
Sbjct: 324 RALSVHLHSDLQGLVQGSDSEAMMNNPGYESSPRERSARGHWYPYNERLICIYCGKSFNQ 383

Query: 411 IQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
             +L +HM +H GI PF C  CGKK+TR   L+ H   H
Sbjct: 384 KGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGH 422


>gi|8922854 kelch-like 26 [Homo sapiens]
          Length = 615

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 46/127 (36%), Positives = 77/127 (60%)

Query: 2   GVKTFTHSSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLV 61
           G    T S+ SHS  +L  L  LR  G   D+ + +  + F AHKVVLAACSD+FR    
Sbjct: 34  GALKCTFSAPSHSTSLLQGLATLRAQGQLLDVVLTINREAFPAHKVVLAACSDYFRAMFT 93

Query: 62  GQAEDENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCS 121
           G   + +++V++L  V+  G   ++++AY+A ++++ + + DVL AA ++QM  V   C 
Sbjct: 94  GGMREASQDVIELKGVSARGLRHIIDFAYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCE 153

Query: 122 EFMKSSI 128
           EF+K+++
Sbjct: 154 EFLKAAM 160


>gi|170650685 zinc finger and BTB domain containing 37 isoform a
           [Homo sapiens]
          Length = 503

 Score = 95.9 bits (237), Expect = 7e-20
 Identities = 118/445 (26%), Positives = 188/445 (42%), Gaps = 45/445 (10%)

Query: 14  SQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENKNVLD 73
           S  +L  LN LR  G  CDI + VQ + FRAHKVVLAA S +FR  +    E    ++  
Sbjct: 15  SNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHM-SLNEMSTVSISV 73

Query: 74  LHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWNTP 133
           + + TV  F  LL + YT  + +   +II  L AAS++QM  +   C++ ++     +  
Sbjct: 74  IKNPTV--FEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGI---HFK 128

Query: 134 NSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRKRKSYIVMSPE 193
            +  E   +  Q    +         ++P  +         P  + +RR + S ++   E
Sbjct: 129 INVAEVEAELSQTRTKHQERPPESHRVTPNLNRSLSPRHNTP--KGNRRGQVSAVLDIRE 186

Query: 194 -SPVKCGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFPFGI----DRRIQPEKVKQA 248
            SP +   +++SPQ++  S+   E+R   +  + A  W    G+     R     +V  A
Sbjct: 187 LSPPE---ESTSPQIIEPSSDV-ESREPILRINRAGQWYVETGVADRGGRSDDEVRVLGA 242

Query: 249 ENTRTLELP---GPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVHEEVSQ 305
            + +T  L    GP E      D  + E   T + + T     V  E  +      +V++
Sbjct: 243 VHIKTENLEEWLGP-ENQPSGEDGSSAEEV-TAMVIDTTGHGSVGQENYTLGSSGAKVAR 300

Query: 306 PVSASQSSLSDQ-QTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSSTNAPPD 364
           P S+     S     VP +E+ +       +S S G +DE      P   S+        
Sbjct: 301 PTSSEVDRFSPSGSVVPLTERHR------ARSESPGRMDE------PKQPSSQV------ 342

Query: 365 DDDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGI 424
           ++  +  V   Y  Y+     S ER     P     C  C   F +  +L +HM +H GI
Sbjct: 343 EESAMMGVS-GYVEYLREQEVS-ERWFRYNP--RLTCIYCAKSFNQKGSLDRHMRLHMGI 398

Query: 425 KPFQCDRCGKKFTRAYSLKMHRLKH 449
            PF C  CGKK+TR   L+ H  KH
Sbjct: 399 TPFVCRMCGKKYTRKDQLEYHIRKH 423


>gi|11056006 kelch-like 12 [Homo sapiens]
          Length = 568

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 41/119 (34%), Positives = 73/119 (61%)

Query: 10  SSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENK 69
           +++H++ +L  +N LR     CD+T+RV+ K F AH++VLAACSD+F      +  ++ K
Sbjct: 12  TNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGK 71

Query: 70  NVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSI 128
             +D+  +T +    LL++ YT T+ +  EN+ ++L AA  +Q+  V   C EF++S +
Sbjct: 72  PYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQL 130


>gi|7662074 zinc finger and BTB domain containing 5 [Homo sapiens]
          Length = 677

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 97/374 (25%), Positives = 161/374 (43%), Gaps = 53/374 (14%)

Query: 13  HSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENKNV- 71
           H +++  +LN  R  G  CD  I V ++ F+AH+ VLAACS  FR        D+  N+ 
Sbjct: 6   HFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALFSVAEGDQTMNMI 65

Query: 72  -LDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILW 130
            LD   VT   F  L++  YT+TL +   N++DVL AAS++ + SV   C  ++ +  L 
Sbjct: 66  QLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDVLLAASHLHLNSVVKACKHYLTTRTLP 125

Query: 131 NTPNSQPEKGLDAGQENN-----------SNCNFTSRDGSISPV----SSECSVVERT-I 174
            +P S+  +   A  + +           S+   +S++G   P     S   ++ +RT  
Sbjct: 126 MSPPSERVQEQSARMQRSFMLQQLGLSIVSSALNSSQNGEEQPAPMSSSMRSNLDQRTPF 185

Query: 175 PVCRESRRK-------RKSYIVMSPESPVKCGTQTSSPQVLNSSASYSENRNQPV----- 222
           P+ R  +RK       R+       ES +   T  + P  ++S   +    +  +     
Sbjct: 186 PMRRLHKRKQSAEERARQRLRPSIDESAISDVTPENGPSGVHSREEFFSPDSLKIVDNPK 245

Query: 223 ---------DSSLAFPWTFPFGIDRRIQPEKVKQAENTRTLELPGPSETGRRMADY---- 269
                    DS++ F  +F    D ++  +    A N   L +   +       D     
Sbjct: 246 ADGMTDNQEDSAIMFDQSFGTQEDAQVPSQSDNSAGNMAQLSMASRATQVETSFDQEAAP 305

Query: 270 ----VTCESTKTTLPLGTEEDVR--VKVERLSDEEVHEEVSQPVSASQSSLSDQQTVPGS 323
                 CE+ +  + LG +E +R  VK E LS  E  +EVS   S ++ S S +  V G 
Sbjct: 306 EKSSFQCENPE--VGLGEKEHMRVVVKSEPLSSPEPQDEVSDVTSQAEGSESVE--VEGV 361

Query: 324 EQVQEDLLISPQSS 337
               E + +SP+SS
Sbjct: 362 VVSAEKIDLSPESS 375



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 17/49 (34%), Positives = 30/49 (61%)

Query: 397 RPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMH 445
           R + C  C   F  + + K+H+ +H+G KP+ C +CGK+F+++  L  H
Sbjct: 611 RKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKH 659


>gi|13540490 BTB and CNC homology 1, basic leucine zipper
           transcription factor 2 [Homo sapiens]
          Length = 841

 Score = 92.8 bits (229), Expect = 6e-19
 Identities = 50/125 (40%), Positives = 78/125 (62%), Gaps = 3/125 (2%)

Query: 6   FTHSSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAE 65
           + + S+ H   +L  LN  R     CD+T+ V+ K FRAH+ VLAACS++F   LVGQ  
Sbjct: 12  YVYESTVHCTNILLGLNDQRKKDILCDVTLIVERKEFRAHRAVLAACSEYFWQALVGQT- 70

Query: 66  DENKNVLDL-HHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFM 124
            +N  V+ L   VT  GF PLL++AYTA L ++ ENI +V+  A +++M ++  +C  F+
Sbjct: 71  -KNDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVIRCAEFLRMHNLEDSCFSFL 129

Query: 125 KSSIL 129
           ++ +L
Sbjct: 130 QTQLL 134


>gi|156616301 kelch-like 32 [Homo sapiens]
          Length = 620

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 46/115 (40%), Positives = 68/115 (59%)

Query: 10  SSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENK 69
           S SH+  +L  LN  R+DG  CDIT+  +++ F AHK VLAACSD+FR        +   
Sbjct: 21  SESHNDSVLAALNQQRSDGILCDITLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGA 80

Query: 70  NVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFM 124
           + ++LH VT  G    LE+AYT  + +    I DVLAA S++Q+  + + CS ++
Sbjct: 81  DEVNLHGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYL 135


>gi|7705375 zinc finger and BTB domain containing 7A [Homo sapiens]
          Length = 584

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 46/133 (34%), Positives = 77/133 (57%), Gaps = 6/133 (4%)

Query: 13  HSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENKNVL 72
           HS ++L  LN  R  G  CD+ I V+ + F  H+ VLAACS +F+      A  + +NV 
Sbjct: 16  HSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFKKLFTSGAVVDQQNVY 75

Query: 73  DLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWNT 132
           ++  V+      L+++AYTATL+++T N+ D+L+AA  +++ +V+  C++ +   IL   
Sbjct: 76  EIDFVSAEALTALMDFAYTATLTVSTANVGDILSAARLLEIPAVSHVCADLLDRQIL--- 132

Query: 133 PNSQPEKGLDAGQ 145
                + G DAGQ
Sbjct: 133 ---AADAGADAGQ 142



 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 25/54 (46%), Positives = 32/54 (59%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
           ++P++C  C VRFTR   LK HM  H+G KP+ C +CG  F   Y LK H   H
Sbjct: 407 EKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVH 460



 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 22/53 (41%), Positives = 32/53 (60%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLK 448
           ++P+ C  CG  F    +LK HM +H+G++P+QCD C K F R+  L  H  K
Sbjct: 435 EKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQCDSCCKTFVRSDHLHRHLKK 487



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 19/50 (38%), Positives = 28/50 (56%)

Query: 400 QCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
           +CP C         L +H+  H+G KP++C+ C  +FTR   LK+H  KH
Sbjct: 383 KCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMRKH 432


>gi|5730122 zinc finger and BTB domain containing 6 [Homo sapiens]
          Length = 424

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 106/438 (24%), Positives = 171/438 (39%), Gaps = 93/438 (21%)

Query: 17  MLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTK-LVGQAEDENKNVLDLH 75
           +L K+N+LR    FCD++I + D  F+ HKV+LAACS F R + L+ Q++     +L   
Sbjct: 19  VLQKMNLLRQQNLFCDVSIYINDTEFQGHKVILAACSTFMRDQFLLTQSKHVRITILQSA 78

Query: 76  HVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWNTPNS 135
            V       LL   YT  L +  + ++  L AASY+QM  +   C+E +   +       
Sbjct: 79  EVGRK----LLLSCYTGALEVKRKELLKYLTAASYLQMVHIVEKCTEALSKYL------- 127

Query: 136 QPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRKRKSYIVMSPESP 195
                +D   +NN+                      +   +C                  
Sbjct: 128 ----EIDLSMKNNN----------------------QHTDLC------------------ 143

Query: 196 VKCGTQTSSPQVLNSSASYSENRNQPVDSSLA-FPWTFPFGIDRRIQPEKVKQAENTRTL 254
                Q+S P V N      E+ N   D  +       P  ID  ++ E+    ++T   
Sbjct: 144 -----QSSDPDVKN------EDENSDKDCEIIEISEDSPVNIDFHVKEEESNALQSTVE- 191

Query: 255 ELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVHE-EVSQPVSASQSS 313
                S T  R  +  + E +   +     E   + VE +S   V   + SQP ++S++S
Sbjct: 192 -----SLTSERK-EMKSPELSTVDIGFKDNEICILHVESISTAGVENGQFSQPCTSSKAS 245

Query: 314 LSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSSTNAPPDDDDRLENVQ 373
           +   +T       Q  L+ S   S +  V     +GL       +T         ++N++
Sbjct: 246 MYFSET-------QHSLINSTVESRVAEVPGNQDQGL----FCENTEGSYGTVSEIQNLE 294

Query: 374 YPYQL-YIAPSTSSTERPSPN-----GPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPF 427
             Y L +  P          N        + F C  CG  FT+ +NL +H+  H GI+PF
Sbjct: 295 EGYSLRHQCPRCPRGFLHVENYLRHLKMHKLFLCLQCGKTFTQKKNLNRHIRGHMGIRPF 354

Query: 428 QCDRCGKKFTRAYSLKMH 445
           QC  C K FT   +L+ H
Sbjct: 355 QCTVCLKTFTAKSTLQDH 372



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 21/49 (42%), Positives = 27/49 (55%)

Query: 397 RPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMH 445
           RPFQC  C   FT    L+ H+ IHSG +P++C  C   F    +LK H
Sbjct: 352 RPFQCTVCLKTFTAKSTLQDHLNIHSGDRPYKCHCCDMDFKHKSALKKH 400


>gi|5174473 intracisternal A particle-promoted polypeptide isoform 1
           [Homo sapiens]
          Length = 584

 Score = 89.0 bits (219), Expect = 8e-18
 Identities = 41/120 (34%), Positives = 72/120 (60%)

Query: 9   SSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDEN 68
           SS  H+Q +L ++N +RN  HFCD+ ++V  + F+AH++VLAA S +F     G  ++ +
Sbjct: 15  SSDKHAQLILAQINKMRNGQHFCDVQLQVGQESFKAHRLVLAASSPYFAALFTGGMKESS 74

Query: 69  KNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSI 128
           K+V+ +  +    F  LL++ YT  ++I   N+ +++ AA  +Q+  V   C EF+K  I
Sbjct: 75  KDVVPILGIEAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLTEVVHLCCEFLKGQI 134


>gi|94721342 zinc finger and BTB domain containing 8A [Homo sapiens]
          Length = 441

 Score = 89.0 bits (219), Expect = 8e-18
 Identities = 106/434 (24%), Positives = 175/434 (40%), Gaps = 96/434 (22%)

Query: 11  SSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENK- 69
           SSH   +L +LN  R    FCD +I V+ K+F+AH+ VL A S +F+  L   +++ ++ 
Sbjct: 4   SSHQSHLLQQLNEQRRQDVFCDCSILVEGKVFKAHRNVLFASSGYFKMLLSQNSKETSQP 63

Query: 70  NVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSIL 129
                   +   F  +L++ Y+  LS+  +N+I+V++AAS++QM  V S C  F+KSS+ 
Sbjct: 64  TTATFQAFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASFLQMTDVISVCKTFIKSSL- 122

Query: 130 WNTPNSQPEKG-LDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRKRKSYI 188
                S+ EK    +  + ++N N   R    S    E S   R+               
Sbjct: 123 ---DISEKEKDRYFSLSDKDANSNGVERSSFYSGGWQEGSSSPRS--------------- 164

Query: 189 VMSPESPVKCGTQTSSPQVLNS---SASYSENRNQPVDSSLAFPWTFPFGIDRRIQPEKV 245
            +SPE     GT   S +  N      +  +N  QP+                + +P K 
Sbjct: 165 HLSPEQ----GTGIISGKSWNKYNYHPASQKNTQQPL---------------AKHEPRK- 204

Query: 246 KQAENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVHEEVSQ 305
           +  + T+ L L  PSE                     T      +  R SD         
Sbjct: 205 ESIKKTKHLRLSQPSEV--------------------THYKSSKREVRTSD--------- 235

Query: 306 PVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSSTNAPPDD 365
             S+S  S S++Q      Q+  ++  +P     G   +  S+  P            DD
Sbjct: 236 --SSSHVSQSEEQA-----QIDAEMDSTPVGYQYGQGSDVTSKSFP------------DD 276

Query: 366 DDRLENVQYPYQLYIAPSTSSTERP-SPNGPDRPFQCPTCGVRFTRIQNLKQHM-LIHSG 423
             R+   + PY  ++    +  +R    +  +RP+ C  CG RF+R+ +L  H   IH  
Sbjct: 277 LPRM-RFKCPYCTHVVKRKADLKRHLRCHTGERPYPCQACGKRFSRLDHLSSHFRTIHQA 335

Query: 424 IKPFQCDRCGKKFT 437
            K   C +C +  T
Sbjct: 336 CK-LICRKCKRHVT 348



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)

Query: 366 DDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIK 425
           D  +++    YQ       +S   P  + P   F+CP C     R  +LK+H+  H+G +
Sbjct: 250 DAEMDSTPVGYQYGQGSDVTSKSFPD-DLPRMRFKCPYCTHVVKRKADLKRHLRCHTGER 308

Query: 426 PFQCDRCGKKFTRAYSLKMH 445
           P+ C  CGK+F+R   L  H
Sbjct: 309 PYPCQACGKRFSRLDHLSSH 328


>gi|223890235 intracisternal A particle-promoted polypeptide isoform
           2 [Homo sapiens]
          Length = 582

 Score = 89.0 bits (219), Expect = 8e-18
 Identities = 41/120 (34%), Positives = 72/120 (60%)

Query: 9   SSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDEN 68
           SS  H+Q +L ++N +RN  HFCD+ ++V  + F+AH++VLAA S +F     G  ++ +
Sbjct: 15  SSDKHAQLILAQINKMRNGQHFCDVQLQVGQESFKAHRLVLAASSPYFAALFTGGMKESS 74

Query: 69  KNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSI 128
           K+V+ +  +    F  LL++ YT  ++I   N+ +++ AA  +Q+  V   C EF+K  I
Sbjct: 75  KDVVPILGIEAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLTEVVHLCCEFLKGQI 134


>gi|45643138 kelch-like 13 [Homo sapiens]
          Length = 655

 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 40/122 (32%), Positives = 72/122 (59%), Gaps = 2/122 (1%)

Query: 9   SSSSHSQEMLGKLNMLRNDGHFCDITIRV--QDKIFRAHKVVLAACSDFFRTKLVGQAED 66
           +S++HS  +L   + LR +G  CD+T+     D  F  H+V++A+ SD+F+    G  ++
Sbjct: 70  TSNTHSSVVLQGFDQLRLEGLLCDVTLMPGDTDDAFPVHRVMMASASDYFKAMFTGGMKE 129

Query: 67  ENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKS 126
           ++   + LH V+  G   ++++ YTA LS+N +N+ D L AAS++Q+  V   C  F+ S
Sbjct: 130 QDLMCIKLHGVSKVGLRKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLIS 189

Query: 127 SI 128
            +
Sbjct: 190 GV 191


>gi|24308181 kelch-like 9 [Homo sapiens]
          Length = 617

 Score = 82.8 bits (203), Expect = 6e-16
 Identities = 40/122 (32%), Positives = 72/122 (59%), Gaps = 2/122 (1%)

Query: 9   SSSSHSQEMLGKLNMLRNDGHFCDITIRVQD--KIFRAHKVVLAACSDFFRTKLVGQAED 66
           +S++HS  +L   + LR +G  CD+T+   D  +IF  H+ ++A+ SD+F+    G  ++
Sbjct: 28  TSNTHSSVVLQGFDQLRIEGLLCDVTLVPGDGDEIFPVHRAMMASASDYFKAMFTGGMKE 87

Query: 67  ENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKS 126
           ++   + LH V   G   ++++ YTA LS+N +N+ D L AAS++Q+  V   C  F+ S
Sbjct: 88  QDLMCIKLHGVNKVGLKKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLIS 147

Query: 127 SI 128
            +
Sbjct: 148 GV 149


>gi|14670366 POZ (BTB) and AT hook containing zinc finger 1 long B
           isoform [Homo sapiens]
          Length = 537

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 47/145 (32%), Positives = 73/145 (50%), Gaps = 23/145 (15%)

Query: 6   FTHSSSSHSQEMLGKLNMLR-NDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQA 64
           +T+  S HS EML  LN  R N G FCD+ +RV D+ F AH+ VLAACS++F +    Q 
Sbjct: 15  YTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQL 74

Query: 65  ED----------------------ENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENII 102
            D                           L++H ++   F  +L++AYT+ + +  E+  
Sbjct: 75  GDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFP 134

Query: 103 DVLAAASYMQMFSVASTCSEFMKSS 127
           +++ AA ++ M SV   C E +K S
Sbjct: 135 ELMTAAKFLLMRSVIEICQEVIKQS 159



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 2/52 (3%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGI--KPFQCDRCGKKFTRAYSLKMH 445
           ++P+ CP CG+RF R   +  H+  H G   KP+ C  CGK F+R   L  H
Sbjct: 380 EKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGH 431



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 6/65 (9%)

Query: 392 PNGPDRPFQ------CPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMH 445
           P+GP +  +      C  CG  F  + +L +H L HSG KP+ C  CG +F R   +  H
Sbjct: 342 PDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYH 401

Query: 446 RLKHE 450
              H+
Sbjct: 402 VRSHD 406



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 1/55 (1%)

Query: 397 RPFQCPTCGVRFTRIQNLKQHM-LIHSGIKPFQCDRCGKKFTRAYSLKMHRLKHE 450
           +P+ C +CG  F+R  +L  H+  +H+  +P +C  C   F     L+ H   HE
Sbjct: 411 KPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHE 465



 Score = 36.6 bits (83), Expect = 0.048
 Identities = 19/54 (35%), Positives = 25/54 (46%), Gaps = 3/54 (5%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKH 449
           +RP +C TC   F     L+ H+  H    P  C  CG K+ RA  +  H  KH
Sbjct: 439 ERPHKCQTCNASFATRDRLRSHLACHEDKVP--CQVCG-KYLRAAYMADHLKKH 489


>gi|14670364 POZ (BTB) and AT hook containing zinc finger 1 short
           isoform [Homo sapiens]
          Length = 537

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 47/145 (32%), Positives = 73/145 (50%), Gaps = 23/145 (15%)

Query: 6   FTHSSSSHSQEMLGKLNMLR-NDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQA 64
           +T+  S HS EML  LN  R N G FCD+ +RV D+ F AH+ VLAACS++F +    Q 
Sbjct: 15  YTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQL 74

Query: 65  ED----------------------ENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENII 102
            D                           L++H ++   F  +L++AYT+ + +  E+  
Sbjct: 75  GDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFP 134

Query: 103 DVLAAASYMQMFSVASTCSEFMKSS 127
           +++ AA ++ M SV   C E +K S
Sbjct: 135 ELMTAAKFLLMRSVIEICQEVIKQS 159



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 2/52 (3%)

Query: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGI--KPFQCDRCGKKFTRAYSLKMH 445
           ++P+ CP CG+RF R   +  H+  H G   KP+ C  CGK F+R   L  H
Sbjct: 380 EKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGH 431



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 6/65 (9%)

Query: 392 PNGPDRPFQ------CPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMH 445
           P+GP +  +      C  CG  F  + +L +H L HSG KP+ C  CG +F R   +  H
Sbjct: 342 PDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYH 401

Query: 446 RLKHE 450
              H+
Sbjct: 402 VRSHD 406


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.128    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,974,088
Number of Sequences: 37866
Number of extensions: 846645
Number of successful extensions: 14294
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1117
Number of HSP's successfully gapped in prelim test: 95
Number of HSP's that attempted gapping in prelim test: 2465
Number of HSP's gapped (non-prelim): 10554
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.