Guide to the Human Genome
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Search of human proteins with 108796063

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|108796063 insulin-like growth factor 2 isoform 1 precursor
[Homo sapiens]
         (180 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504609 insulin-like growth factor 2 isoform 1 precursor [Hom...   373   e-104
gi|108796063 insulin-like growth factor 2 isoform 1 precursor [H...   373   e-104
gi|189083846 insulin-like growth factor 2 isoform 2 [Homo sapiens]    373   e-104
gi|11024682 insulin-like growth factor 1 isoform 4 preproprotein...    94   8e-20
gi|163659903 insulin-like growth factor 1 isoform 3 preproprotei...    94   8e-20
gi|163659901 insulin-like growth factor 1 isoform 2 preproprotei...    94   8e-20
gi|163659899 insulin-like growth factor 1 isoform 1 preproprotei...    94   8e-20
gi|4557671 proinsulin precursor [Homo sapiens]                         52   2e-07
gi|109148522 insulin- insulin-like growth factor 2 [Homo sapiens]      39   0.003
gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Ho...    30   1.5  
gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Ho...    30   1.5  
gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Ho...    30   1.5  
gi|71725371 solute carrier family 10 (sodium/bile acid cotranspo...    29   2.5  
gi|47419930 chondroitin sulfate proteoglycan 4 [Homo sapiens]          28   4.3  
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]        28   4.3  
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    28   5.6  
gi|169167740 PREDICTED: hypothetical protein [Homo sapiens]            27   9.5  
gi|239750488 PREDICTED: similar to CNOT4 protein, partial [Homo ...    27   9.5  
gi|113416994 PREDICTED: hypothetical protein [Homo sapiens]            27   9.5  
gi|239744787 PREDICTED: similar to CNOT4 protein, partial [Homo ...    27   9.5  
gi|113416470 PREDICTED: hypothetical protein [Homo sapiens]            27   9.5  
gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens]     27   9.5  
gi|157426856 armadillo repeat containing 5 isoform a [Homo sapiens]    27   9.5  

>gi|4504609 insulin-like growth factor 2 isoform 1 precursor [Homo
           sapiens]
          Length = 180

 Score =  373 bits (957), Expect = e-104
 Identities = 180/180 (100%), Positives = 180/180 (100%)

Query: 1   MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 60
           MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
Sbjct: 1   MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 60

Query: 61  RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 120
           RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
Sbjct: 61  RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 120

Query: 121 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 180
           QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Sbjct: 121 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 180


>gi|108796063 insulin-like growth factor 2 isoform 1 precursor [Homo
           sapiens]
          Length = 180

 Score =  373 bits (957), Expect = e-104
 Identities = 180/180 (100%), Positives = 180/180 (100%)

Query: 1   MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 60
           MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
Sbjct: 1   MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 60

Query: 61  RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 120
           RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
Sbjct: 61  RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 120

Query: 121 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 180
           QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Sbjct: 121 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 180


>gi|189083846 insulin-like growth factor 2 isoform 2 [Homo sapiens]
          Length = 236

 Score =  373 bits (957), Expect = e-104
 Identities = 180/180 (100%), Positives = 180/180 (100%)

Query: 1   MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 60
           MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
Sbjct: 57  MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 116

Query: 61  RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 120
           RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
Sbjct: 117 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 176

Query: 121 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 180
           QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Sbjct: 177 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 236


>gi|11024682 insulin-like growth factor 1 isoform 4 preproprotein
           [Homo sapiens]
          Length = 153

 Score = 93.6 bits (231), Expect = 8e-20
 Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)

Query: 10  LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 65
           L LLTF + A+         ETLCG ELVD LQFVCGDRGFYF++P    S   R    G
Sbjct: 37  LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 90

Query: 66  IVEECCFRSCDLALLETYCA--TPAKSERDV 94
           IV+ECCFRSCDL  LE YCA   PAKS R V
Sbjct: 91  IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 121


>gi|163659903 insulin-like growth factor 1 isoform 3 preproprotein
           [Homo sapiens]
          Length = 195

 Score = 93.6 bits (231), Expect = 8e-20
 Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)

Query: 10  LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 65
           L LLTF + A+         ETLCG ELVD LQFVCGDRGFYF++P    S   R    G
Sbjct: 37  LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 90

Query: 66  IVEECCFRSCDLALLETYCA--TPAKSERDV 94
           IV+ECCFRSCDL  LE YCA   PAKS R V
Sbjct: 91  IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 121


>gi|163659901 insulin-like growth factor 1 isoform 2 preproprotein
           [Homo sapiens]
          Length = 137

 Score = 93.6 bits (231), Expect = 8e-20
 Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)

Query: 10  LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 65
           L LLTF + A+         ETLCG ELVD LQFVCGDRGFYF++P    S   R    G
Sbjct: 21  LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 74

Query: 66  IVEECCFRSCDLALLETYCA--TPAKSERDV 94
           IV+ECCFRSCDL  LE YCA   PAKS R V
Sbjct: 75  IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 105


>gi|163659899 insulin-like growth factor 1 isoform 1 preproprotein
           [Homo sapiens]
          Length = 158

 Score = 93.6 bits (231), Expect = 8e-20
 Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)

Query: 10  LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 65
           L LLTF + A+         ETLCG ELVD LQFVCGDRGFYF++P    S   R    G
Sbjct: 37  LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 90

Query: 66  IVEECCFRSCDLALLETYCA--TPAKSERDV 94
           IV+ECCFRSCDL  LE YCA   PAKS R V
Sbjct: 91  IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 121


>gi|4557671 proinsulin precursor [Homo sapiens]
          Length = 110

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 27/103 (26%)

Query: 9   MLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRV--------- 59
           +L LL  LA      AA   ++ LCG  LV+ L  VCG+RGF+++    R          
Sbjct: 7   LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQV 66

Query: 60  ------------------SRRSRGIVEECCFRSCDLALLETYC 84
                             S + RGIVE+CC   C L  LE YC
Sbjct: 67  ELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109


>gi|109148522 insulin- insulin-like growth factor 2 [Homo sapiens]
          Length = 200

 Score = 38.5 bits (88), Expect = 0.003
 Identities = 20/50 (40%), Positives = 28/50 (56%)

Query: 9  MLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR 58
          +L LL  LA      AA   ++ LCG  LV+ L  VCG+RGF+++    R
Sbjct: 7  LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRR 56


>gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
            sapiens]
          Length = 2139

 Score = 29.6 bits (65), Expect = 1.5
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 4/46 (8%)

Query: 128  RGLPALLRARRGH----VLAKELEAFREAKRHRPLIALPTQDPAHG 169
            RG PAL R   GH    + +K L+A  +   HR L    T+ P HG
Sbjct: 1666 RGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHG 1711


>gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
            sapiens]
          Length = 2139

 Score = 29.6 bits (65), Expect = 1.5
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 4/46 (8%)

Query: 128  RGLPALLRARRGH----VLAKELEAFREAKRHRPLIALPTQDPAHG 169
            RG PAL R   GH    + +K L+A  +   HR L    T+ P HG
Sbjct: 1666 RGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHG 1711


>gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
            sapiens]
          Length = 2139

 Score = 29.6 bits (65), Expect = 1.5
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 4/46 (8%)

Query: 128  RGLPALLRARRGH----VLAKELEAFREAKRHRPLIALPTQDPAHG 169
            RG PAL R   GH    + +K L+A  +   HR L    T+ P HG
Sbjct: 1666 RGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHG 1711


>gi|71725371 solute carrier family 10 (sodium/bile acid
           cotransporter family), member 7 isoform b [Homo sapiens]
          Length = 340

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 2/57 (3%)

Query: 1   MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQ--FVCGDRGFYFSRP 55
           +GIPM K +      L+  S  +  Y P++ L G  LV T++   V   +G   +RP
Sbjct: 282 LGIPMLKIVFAGHEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRP 338


>gi|47419930 chondroitin sulfate proteoglycan 4 [Homo sapiens]
          Length = 2322

 Score = 28.1 bits (61), Expect = 4.3
 Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 3/46 (6%)

Query: 133  LLRARRGHVLAKELEAFREAKRHR--PLIALPTQDPAHGGAP-PEM 175
            +L A+  + LA + E FR+ +  +  PL A+P Q P  GG P PE+
Sbjct: 2259 VLTAKPRNGLAGDTETFRKVEPGQAIPLTAVPGQGPPPGGQPDPEL 2304


>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
          Length = 268

 Score = 28.1 bits (61), Expect = 4.3
 Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 7/80 (8%)

Query: 51  YFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPV 110
           YF+   S  SR   G+   CC +     ++ T C   A+ + +V     +       Y  
Sbjct: 167 YFNCTDSNASRERCGVPFSCCTKDPAEDVINTQCGYDARQKPEVDQQIVI-------YTK 219

Query: 111 GKFFQYDTWKQSTQRLRRGL 130
           G   Q++ W Q    +  G+
Sbjct: 220 GCVPQFEKWLQDNLTIVAGI 239


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 27.7 bits (60), Expect = 5.6
 Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 8/67 (11%)

Query: 120 KQSTQRLRRGLPALLRARRGHVLAKELEAFREAKR-------HRPLIALPTQDPAHGGAP 172
           ++ + + R+ LPA  RAR     A EL    +A+        HRP    P+  P H   P
Sbjct: 433 RERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGH-TLP 491

Query: 173 PEMASNR 179
           P+  S R
Sbjct: 492 PKPPSPR 498


>gi|169167740 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 302

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 14/44 (31%), Positives = 20/44 (45%)

Query: 89  KSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPA 132
           ++  D   P    P + PR+P  +      WK S  +  RGLPA
Sbjct: 111 EARNDHRPPGRAPPRHAPRFPRPRMRFPQAWKASRAKEPRGLPA 154


>gi|239750488 PREDICTED: similar to CNOT4 protein, partial [Homo
           sapiens]
          Length = 318

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 12/25 (48%), Positives = 15/25 (60%)

Query: 86  TPAKSERDVSTPPTVLPDNFPRYPV 110
           +P  S RD  +PPT LP + P  PV
Sbjct: 154 SPTTSNRDRPSPPTGLPKSSPVIPV 178


>gi|113416994 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 302

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 14/44 (31%), Positives = 20/44 (45%)

Query: 89  KSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPA 132
           ++  D   P    P + PR+P  +      WK S  +  RGLPA
Sbjct: 111 EARNDHRPPGRAPPRHAPRFPRPRMRFPQAWKASRAKEPRGLPA 154


>gi|239744787 PREDICTED: similar to CNOT4 protein, partial [Homo
           sapiens]
          Length = 318

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 12/25 (48%), Positives = 15/25 (60%)

Query: 86  TPAKSERDVSTPPTVLPDNFPRYPV 110
           +P  S RD  +PPT LP + P  PV
Sbjct: 154 SPTTSNRDRPSPPTGLPKSSPVIPV 178


>gi|113416470 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 302

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 14/44 (31%), Positives = 20/44 (45%)

Query: 89  KSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPA 132
           ++  D   P    P + PR+P  +      WK S  +  RGLPA
Sbjct: 111 EARNDHRPPGRAPPRHAPRFPRPRMRFPQAWKASRAKEPRGLPA 154


>gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens]
          Length = 725

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%)

Query: 132 ALLRARRGHVLAKE-LEAFREAKRHRPLIALPTQDPAHGGAPPE 174
           ALL  R  H+ A   +E FR     RPL+AL  +  A G AP +
Sbjct: 43  ALLALRTRHIKAAGGIERFRARGGLRPLLALLRRAAAAGSAPSQ 86


>gi|157426856 armadillo repeat containing 5 isoform a [Homo sapiens]
          Length = 935

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%)

Query: 132 ALLRARRGHVLAKE-LEAFREAKRHRPLIALPTQDPAHGGAPPE 174
           ALL  R  H+ A   +E FR     RPL+AL  +  A G AP +
Sbjct: 43  ALLALRTRHIKAAGGIERFRARGGLRPLLALLRRAAAAGSAPSQ 86


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.138    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,785,672
Number of Sequences: 37866
Number of extensions: 348451
Number of successful extensions: 1040
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1018
Number of HSP's gapped (non-prelim): 24
length of query: 180
length of database: 18,247,518
effective HSP length: 96
effective length of query: 84
effective length of database: 14,612,382
effective search space: 1227440088
effective search space used: 1227440088
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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