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Search of human proteins with 45505178
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45505178 cancer antigen 1 [Homo sapiens]
(641 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45505178 cancer antigen 1 [Homo sapiens] 1257 0.0
gi|71061468 centromere protein E [Homo sapiens] 89 1e-17
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 86 8e-17
gi|42794779 myosin 18A isoform b [Homo sapiens] 86 1e-16
gi|28416946 myosin 18A isoform a [Homo sapiens] 86 1e-16
gi|9910266 kinesin family member 15 [Homo sapiens] 85 2e-16
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 85 2e-16
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 84 4e-16
gi|55770834 centromere protein F [Homo sapiens] 80 4e-15
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 80 8e-15
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 79 1e-14
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 78 2e-14
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 77 4e-14
gi|156104908 myosin heavy chain 6 [Homo sapiens] 76 1e-13
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 75 1e-13
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 75 1e-13
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 75 2e-13
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 74 3e-13
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 74 3e-13
gi|118498362 kinectin 1 isoform b [Homo sapiens] 74 4e-13
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 74 4e-13
gi|118498368 kinectin 1 isoform c [Homo sapiens] 74 5e-13
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 74 5e-13
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 73 7e-13
gi|118498356 kinectin 1 isoform a [Homo sapiens] 73 9e-13
gi|33620775 kinectin 1 isoform a [Homo sapiens] 73 9e-13
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 73 9e-13
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 73 9e-13
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 73 9e-13
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 72 2e-12
>gi|45505178 cancer antigen 1 [Homo sapiens]
Length = 641
Score = 1257 bits (3252), Expect = 0.0
Identities = 641/641 (100%), Positives = 641/641 (100%)
Query: 1 MTEKPEFQSQVYNYAKDNNIKQDSFKEENPMETSVSANTDQLGNEYFRQPPPRSPPLIHC 60
MTEKPEFQSQVYNYAKDNNIKQDSFKEENPMETSVSANTDQLGNEYFRQPPPRSPPLIHC
Sbjct: 1 MTEKPEFQSQVYNYAKDNNIKQDSFKEENPMETSVSANTDQLGNEYFRQPPPRSPPLIHC 60
Query: 61 SGEMLKFTEKSLAKSIAKESALNPSQPPSFLCKTAVPSKEIQNYGEIPEMSVSYEKEVTA 120
SGEMLKFTEKSLAKSIAKESALNPSQPPSFLCKTAVPSKEIQNYGEIPEMSVSYEKEVTA
Sbjct: 61 SGEMLKFTEKSLAKSIAKESALNPSQPPSFLCKTAVPSKEIQNYGEIPEMSVSYEKEVTA 120
Query: 121 EGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTN 180
EGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTN
Sbjct: 121 EGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTN 180
Query: 181 RKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKN 240
RKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKN
Sbjct: 181 RKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKN 240
Query: 241 DTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVS 300
DTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVS
Sbjct: 241 DTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVS 300
Query: 301 QYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEK 360
QYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEK
Sbjct: 301 QYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEK 360
Query: 361 ENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEE 420
ENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEE
Sbjct: 361 ENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEE 420
Query: 421 QNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASK 480
QNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASK
Sbjct: 421 QNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASK 480
Query: 481 MHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDE 540
MHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDE
Sbjct: 481 MHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDE 540
Query: 541 AKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHL 600
AKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHL
Sbjct: 541 AKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHL 600
Query: 601 EDLIRKPREKARKPRSKSLENHPKSMTMMPALFKENRNDLD 641
EDLIRKPREKARKPRSKSLENHPKSMTMMPALFKENRNDLD
Sbjct: 601 EDLIRKPREKARKPRSKSLENHPKSMTMMPALFKENRNDLD 641
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 89.4 bits (220), Expect = 1e-17
Identities = 109/495 (22%), Positives = 226/495 (45%), Gaps = 71/495 (14%)
Query: 149 EMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKI 208
E D ++ E LQ + + N KH ++E+++ C E+ + EL++ +
Sbjct: 1443 EKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAH--CCLKEQEETINELRVNL 1500
Query: 209 TKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKE 268
++++ I I K E + + +++K + I EK + Q ++ Q+ + E + KE
Sbjct: 1501 SEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQ-----ISEVQEKVNELKQFKE 1555
Query: 269 MLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQ-LKKELE 327
+K K + + E M E+ + + + +++ + K++EE++R+Q+ L+ E +
Sbjct: 1556 -----HRKAKDSALQSIESKMLELTNRLQESQEEIQI---MIKEKEEMKRVQEALQIERD 1607
Query: 328 KATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMS 387
+ + +++ + KE+QE+E+ L+ +E + E + LK + E TQ NL
Sbjct: 1608 QLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFE---TQKLNL---- 1660
Query: 388 ENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITK- 446
EN T+NI+L Q ++E E + ++ K E QLK+ L E + D+ K
Sbjct: 1661 ENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQ 1720
Query: 447 -DTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHF 505
+ K H +L K + K+ +++ ++ + D EH
Sbjct: 1721 EELKIVHMHL----------------KEHQETIDKLRGIVSEKTNEIS---NMQKDLEHS 1761
Query: 506 KESEKVSDIMLQ---KLKSLHLK--KKTLDK------EVIDCDSDEAKSIRDVPTLLGAK 554
++ K D+ +Q ++ +HLK ++T+DK E D S+ K + + L K
Sbjct: 1762 NDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEK 1821
Query: 555 LDKYHSLNEELDFL----------VTSYEEI-IECADQRLAISHSQIAHL---EERNKHL 600
+ + + +L L V+ E++ + DQ L +S +I +L ++ +++L
Sbjct: 1822 IQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENL 1881
Query: 601 EDL--IRKPREKARK 613
E++ + K R+ R+
Sbjct: 1882 EEMKSVMKERDNLRR 1896
Score = 72.0 bits (175), Expect = 2e-12
Identities = 111/506 (21%), Positives = 225/506 (44%), Gaps = 67/506 (13%)
Query: 152 DWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQ 211
D+EQ + + ++E+ +N+ + L +K + + L+ Y + +ELQ K +
Sbjct: 828 DFEQKYKMV--LEENERMNQEIVNLSKEAQKFDSSLGALKTELSY---KTQELQEKTREV 882
Query: 212 QVFIDVINKLKENVEELIEDKYKIILEKN-DTKKTLQNLEEVLANTQKHLQESRNDKEML 270
Q ++ + +LKE +E + EK T+K Q LEEV TQ+ + + +E L
Sbjct: 883 QERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEK-DDLKQLQESL 941
Query: 271 QLQFKKIKAN-YVCLQERYMTEMQQKN--KSVSQYLEMDKTL-SKKEEEVERLQQLKKEL 326
Q++ ++K++ + + T+ Q +N +S+ Q+ E TL SK EEV R +
Sbjct: 942 QIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSR----NLHM 997
Query: 327 EKATASALDLL---------KREKEAQEQEFLSLQEEFQKLEKEN------LEERQKLKS 371
E+ T D K++ EA+ + L+ + ++ ++ ++E+ +L+
Sbjct: 998 EENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQ 1057
Query: 372 RLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQ 431
LE ++ + L+ + I+ Q+++ + +E K ++ VA+ + + E ++
Sbjct: 1058 MLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSR 1117
Query: 432 LKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGL 491
D+L EV EE+L +++ QL K LL + +
Sbjct: 1118 TCDRLAEV-----------------------EEKLK----EKSQQLQEKQQQLLNVQEEM 1150
Query: 492 LTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLL 551
Q IN + E+ K K ++ L+ +++ L+ + ++ + +E KSI +L
Sbjct: 1151 SEMQKKIN-EIENLKNELKNKELTLEHMETERLEL----AQKLNENYEEVKSITKERKVL 1205
Query: 552 GAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKPREK- 610
+ + + L + E + L I+H HL+E + +++L R EK
Sbjct: 1206 KELQKSFETERDHLRGYIREIEATGLQTKEELKIAH---IHLKEHQETIDELRRSVSEKT 1262
Query: 611 ARKPRSKSLE-NHPKSMTMMPALFKE 635
A+ ++ LE +H K +P L +E
Sbjct: 1263 AQIINTQDLEKSHTKLQEEIPVLHEE 1288
Score = 69.7 bits (169), Expect = 8e-12
Identities = 102/512 (19%), Positives = 220/512 (42%), Gaps = 90/512 (17%)
Query: 168 ALNEVLQK------LKHTNRKQEVRIQELQCSNL----YLEKRVKELQMKITKQQVFIDV 217
A+NE +K LK Q++ ++ ++ N+ L + ++E++ +TK++ +
Sbjct: 1635 AVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMR-SVTKERDDLRS 1693
Query: 218 I--------NKLKENVEELI------EDKYKII-LEKNDTKKTLQNLEEVLANTQKHLQE 262
+ ++LKEN+ E I +++ KI+ + + ++T+ L +++ +
Sbjct: 1694 VEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISN 1753
Query: 263 SRNDKEMLQLQFKKIKANYVCLQERY-MTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQ 321
+ D L+ +KA + +QE + M K + + +DK E+ ++L
Sbjct: 1754 MQKD---LEHSNDALKAQDLKIQEELRIAHMHLKEQQET----IDKLRGIVSEKTDKLSN 1806
Query: 322 LKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVR 381
++K+LE + A + ++ E +A E + ++L K+++ E QK S +E+L Q++
Sbjct: 1807 MQKDLENSNAKLQEKIQ-ELKANEHQLITL--------KKDVNETQKKVSEMEQLKKQIK 1857
Query: 382 NLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLK 441
+ +N+ L Q+++E E + ++ K E QLK+ L+E
Sbjct: 1858 DQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKA 1917
Query: 442 SD------------ITKDTKTTHSNLLPDCSPCEERLNPADI-----KRASQLASKMHSL 484
D ++K+ K T L S E+ + +DI K +L K+ L
Sbjct: 1918 RDLEIQQELKTARMLSKEHKETVDKLREKIS--EKTIQISDIQKDLDKSKDELQKKIQEL 1975
Query: 485 LALMVGLLTCQDIIN------SDAEHFKESEKVSDIMLQ--KLKSLHLKKKTLDK----E 532
+ LL ++ +N ++ E K+ + ++ +Q ++ + L KK +
Sbjct: 1976 QKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIR 2035
Query: 533 VIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAH 592
++ + DE + I++ SL E D + + E+I Q + +
Sbjct: 2036 IVAKERDELRRIKE-------------SLKMERDQFIATLREMIARDRQNHQVKPEK-RL 2081
Query: 593 LEERNKHLEDLIRK--PREKARKPRSKSLENH 622
L + +HL + +R+ R K R +++H
Sbjct: 2082 LSDGQQHLTESLREKCSRIKELLKRYSEMDDH 2113
Score = 63.2 bits (152), Expect = 7e-10
Identities = 109/515 (21%), Positives = 214/515 (41%), Gaps = 94/515 (18%)
Query: 145 RENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKEL 204
+E ++ ++E + QE ++E+ LK+ + EV Q+L+ + ++E
Sbjct: 529 KEKNDLDEFEALERKTKKDQEMQLIHEI-SNLKNLVKHAEVYNQDLENELSSKVELLREK 587
Query: 205 QMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEV------------ 252
+ +I K Q +ID ++ EN++ + + I + K+TL + E V
Sbjct: 588 EDQIKKLQEYID--SQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLR 645
Query: 253 ------------LANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVS 300
LA T K ++ ND ++ Q Q + K V L++ + + K S
Sbjct: 646 SENLELKEKMKELATTYKQME---NDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTS 702
Query: 301 ------------------QYLEMDKTLSKKEEEVERLQQ---LKKELEKATASALDLLKR 339
+ ++ K L+K+ EE E L++ L EL K+ S ++ L++
Sbjct: 703 LIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSEL-KSLPSEVERLRK 761
Query: 340 EKEAQEQEFLSLQEEFQKL-----EKEN-----LEERQKLKSRLEKLLTQVRNLQFMSEN 389
E + + +E + E KL KE+ LEE K K L + ++ +N
Sbjct: 762 EIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQN 821
Query: 390 ERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTK 449
+T ++ +Q+ V EN ++ Q++ ++ AQ D LK++++ T+
Sbjct: 822 FKTLHMDFEQKYKMVLEENERMNQEIVNLSKE--------AQKFDSSLGALKTELSYKTQ 873
Query: 450 TTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESE 509
L +ERLN + + QL ++ +L + + E +E
Sbjct: 874 ----ELQEKTREVQERLNEME-QLKEQLENRDSTLQTV-------------EREKTLITE 915
Query: 510 KVSDIMLQKLKSLHLKKKTLD--KEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDF 567
K+ L+++K+L +K L +E + + D+ KS D+ + +D L L+
Sbjct: 916 KLQQ-TLEEVKTLTQEKDDLKQLQESLQIERDQLKS--DIHDTVNMNIDTQEQLRNALES 972
Query: 568 LVTSYEEIIECADQRLAISHSQIAHLEERNKHLED 602
L ++E I +++ S+ H+EE +D
Sbjct: 973 L-KQHQETINTLKSKISEEVSRNLHMEENTGETKD 1006
Score = 58.5 bits (140), Expect = 2e-08
Identities = 92/434 (21%), Positives = 188/434 (43%), Gaps = 47/434 (10%)
Query: 200 RVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKH 259
R+KEL + ++ + +N+L ++E+ IE +K + + NL T KH
Sbjct: 2099 RIKELLKRYSEMDDHYECLNRLSLDLEKEIE------FQKELSMRVKANLSLPYLQT-KH 2151
Query: 260 LQESRNDKEMLQLQFKKI--KANYVCLQERYMTEMQQKNKSVSQYLEMD--KTLSKKEEE 315
+++ + ++F +I K YV Y+T+++++ EMD + K++E
Sbjct: 2152 IEKLFTANQRCSMEFHRIMKKLKYVL---SYVTKIKEEQHESINKFEMDFIDEVEKQKEL 2208
Query: 316 VERLQQLKKELEKATASALDLLKRE----------KEAQEQEFLSLQEEFQKLEKENLEE 365
+ ++Q L+++ + + DL + K+ E EF S++ EFQ++ L
Sbjct: 2209 LIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQV----LSN 2264
Query: 366 RQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVP 425
R+++ LE+ L +++ + + +N ++ Q N N + + EE++
Sbjct: 2265 RKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATI 2324
Query: 426 KFETAQ----LKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKM 481
E Q LK++ E++ K+ T KT+ ++ ++ NP RA+QL ++
Sbjct: 2325 SKEWEQDLKSLKEKNEKLFKNYQT--LKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEK 2382
Query: 482 HSLL--ALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSD 539
L +L + + + KE E +DI+ + +H K L+K +
Sbjct: 2383 IRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEK------TK 2436
Query: 540 EAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKH 599
E + LGAK K EE++ L +I + +I+ + ++
Sbjct: 2437 ETIQVLQDKVALGAKPYK-----EEIEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEY 2491
Query: 600 LEDLIRKPREKARK 613
+++IR RE R+
Sbjct: 2492 QKEVIRLLRENLRR 2505
Score = 39.3 bits (90), Expect = 0.011
Identities = 93/458 (20%), Positives = 185/458 (40%), Gaps = 66/458 (14%)
Query: 159 SLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVI 218
++ PV D L + K + E+ L++ KE+ M + KQ + +
Sbjct: 307 TITPVSFDETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEI-MDLKKQLEEVSLE 365
Query: 219 NKL----KENVEELIEDKYKIILEKNDTKKTLQNLEEVLANT-----QKHLQESRNDKEM 269
+ K+ + +L+E+K +L+K +K ++NL +L + Q+ L+ R +
Sbjct: 366 TRAQAMEKDQLAQLLEEKD--LLQKVQNEK-IENLTRMLVTSSSLTLQQELKAKRKRRVT 422
Query: 270 LQL-QFKKIKANYVCLQERYMTEMQQKNKSVSQYL--EMDKTLSKKEEEVERLQQLKKEL 326
L + K+K + Q T + K +S L E+D+++ + + E+
Sbjct: 423 WCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLDTLSEI 482
Query: 327 EKATASALDLLKREKEAQEQEFLSLQEEFQKL---------EKENLEERQKLKSRLEK-- 375
E A+ L +E E E SL+ ++ L EKE +E + K K+ L++
Sbjct: 483 EWNPATKL----LNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFE 538
Query: 376 -------------LLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQN 422
L+ ++ NL+ + ++ N L+ +++ + + Q+ + +E
Sbjct: 539 ALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQE-- 596
Query: 423 YVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQ-LASKM 481
Y+ + +K L L+S +D K L + D KR S L S+
Sbjct: 597 YIDSQKLENIKMDLSYSLES--IEDPKQMKQTLF------DAETVALDAKRESAFLRSEN 648
Query: 482 HSLLALMVGLLTCQDIINSDAEHFK---ESEKVSDIMLQKLKSLHLKKKTLDKEVID--- 535
L M L T + +D + ++ E++K + L+K + T +ID
Sbjct: 649 LELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKV 708
Query: 536 -----CDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFL 568
C+ + I D+ L ++++ +L EE+ L
Sbjct: 709 PKDLLCNLELEGKITDLQKELNKEVEENEALREEVILL 746
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 86.3 bits (212), Expect = 8e-17
Identities = 131/567 (23%), Positives = 237/567 (41%), Gaps = 129/567 (22%)
Query: 149 EMPDWEQSAESLQPVQEDMALNEV-LQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMK 207
E+ D E ++LQ E++ ++ L++L+ N+ E +L+ LEK K L+ +
Sbjct: 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Query: 208 I-----TKQQVFIDVINKLKEN----------------VEELIEDKYKIILEKNDTKKTL 246
T ++ + + N KEN ++EL ++ +++ KTL
Sbjct: 845 AEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTL 904
Query: 247 QNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLE-- 304
L E L + + Q+ ND E L + +KI N +ER + + Q + S + LE
Sbjct: 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLN----KERLLHDEQSTDDSRYKLLESK 960
Query: 305 ----MDKTLSKKEEEVERL-----------QQLKKELEKATASALDLLKR---------- 339
+ K+L KEE++ L QQL++EL+ + L +R
Sbjct: 961 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS 1020
Query: 340 ----------EKEAQE--QEFLSLQEEFQKLEKENLE---ERQKLKSRLEKLLTQVRNLQ 384
E+E+QE +E L +++ ++E+ N E+Q LK++L++L TQ NLQ
Sbjct: 1021 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ 1080
Query: 385 FMSENERTKNIKLQQQINEVKNENAKLK-------QQVARSEEQNYVPKFETAQLKDQLE 437
+ + + LQ+Q ++ +NAKL+ Q QN + + L+++ E
Sbjct: 1081 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE 1140
Query: 438 EVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQ---LASKMHSLLALMVGL-LT 493
V+K +D K+ + +L+ D E+L ++AS+ L SK +L + L +
Sbjct: 1141 SVIKE--REDLKSLYDSLIKD----HEKLELLHERQASEYESLISKHGTLKSAHKNLEVE 1194
Query: 494 CQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDK---------------------- 531
+D+ + + K+ ++ D L+K+ + +K L+
Sbjct: 1195 HRDLEDRYNQLLKQKGQLED--LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNH 1252
Query: 532 ---------EVIDCDSDEAKSIRD----VPTLLGAKLDKYHSLNEELDFLVTSYEEIIEC 578
EV+ D KS+ + T L A+ K ++LD T E
Sbjct: 1253 TYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCEL 1312
Query: 579 ADQRLAISHSQIAHLEERNKHLEDLIR 605
Q +LEE N+HL D I+
Sbjct: 1313 LSQLK-------GNLEEENRHLLDQIQ 1332
Score = 76.6 bits (187), Expect = 6e-14
Identities = 116/496 (23%), Positives = 212/496 (42%), Gaps = 92/496 (18%)
Query: 171 EVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIE 230
++ ++L+H K E R +EL+ +LEK + LQ KIT ++ + I L++ EL
Sbjct: 612 QIKKELEHYKEKGE-RAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELER 670
Query: 231 DKYKI---------------ILEKNDTKKTLQNLE------------EVLANTQKHLQES 263
+ K+ LEK +++ +NLE +A Q +E
Sbjct: 671 ENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKEL 730
Query: 264 RNDK-------EMLQLQFKKIKANYVCLQ------ERYMTEMQQKNKSVSQYLEMDKTLS 310
++K E+L+ FKK + V Q +R ++ NK + Q ++ L
Sbjct: 731 ESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ---LESELQ 787
Query: 311 KKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLK 370
E E + LQ+ +EL K ++ L+ L++E ++ EQE L+++ ++LEKEN RQ+ +
Sbjct: 788 DLEMENQTLQKNLEEL-KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Query: 371 ---SRLEKLLTQVRNLQFMSENER-TKNIKLQQQ----INEVKNENAKLKQQ-------V 415
+ LE+ ++ NL+ EN+ +K I + ++ + E++ EN +L ++ +
Sbjct: 847 IKDTTLEENNVKIGNLE--KENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTL 904
Query: 416 ARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERL----NPADI 471
E K +T Q+ + LE K TH L +ERL D
Sbjct: 905 VTLREDLVSEKLKTQQMNNDLE-----------KLTHE--LEKIGLNKERLLHDEQSTDD 951
Query: 472 KRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDK 531
R L SK+ S L L ++ I + +ES + + Q+LK++ + L +
Sbjct: 952 SRYKLLESKLES--TLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ 1009
Query: 532 EVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAIS----- 586
DE + ++ P + G E L+ + +IE +
Sbjct: 1010 R-----QDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQA 1064
Query: 587 -HSQIAHLEERNKHLE 601
+Q+ LE +N +L+
Sbjct: 1065 LKTQLKQLETQNNNLQ 1080
Score = 67.8 bits (164), Expect = 3e-11
Identities = 103/532 (19%), Positives = 235/532 (44%), Gaps = 73/532 (13%)
Query: 141 SEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLK-------HTNRKQEVRIQELQCS 193
SE R + D E ++ ++ED N+VL + K R + ++ EL+
Sbjct: 327 SEVSRYKERLHDIEFYKARVEELKED---NQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Query: 194 NLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVL 253
NL L+ ++ +++M+ ++ +EEL+E+ + + + Q+++E L
Sbjct: 384 NLQLKAKLHDMEMERDMD----------RKKIEELMEENMTLEMAQK------QSMDESL 427
Query: 254 ANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLE-MDKTLSKK 312
+ L++ E+ + K + L + +++ +N+S+++ +E + T+
Sbjct: 428 -HLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSV 486
Query: 313 EEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSR 372
E ++ +++KE ++ + +++L+ E ++Q + Q + L KE + + +++
Sbjct: 487 EGNASKILKMEKENQRLSKK-VEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETL 545
Query: 373 LEKLLTQVRNLQFMSE--NERTKNIKLQQQIN------EVKNENAKLKQQVARSEEQNYV 424
E Q++ L+ +E N+ +++ + QI+ +++ EN L + + + +
Sbjct: 546 RENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSK 605
Query: 425 PKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSL 484
+FE Q+K +LE + E L+ +++ ++L K +
Sbjct: 606 IEFEKRQIKKELEHYKEKG-------------ERAEELENELH--HLEKENELLQKKITN 650
Query: 485 LALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSI 544
L + + + NS+ E +E+ K+ L K+L + ++L+KE D + +
Sbjct: 651 LKITCEKIEALEQENSELE--RENRKLKK-TLDSFKNLTFQLESLEKENSQLDEENLELR 707
Query: 545 RDVPTLLGAKL-------------DKYHSLNEELDFLVTSYE--EIIECADQRLAISHSQ 589
R+V +L A + + L + L+ L S++ E +E + Q L I + +
Sbjct: 708 RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQR 767
Query: 590 IAH-LEERNKHLEDLIRKPR--EKARKPRSKSLENHPKSMTMMPALFKENRN 638
+ LE NK ++ L + + E + K+LE S + L KEN++
Sbjct: 768 LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKS 819
Score = 53.5 bits (127), Expect = 6e-07
Identities = 81/419 (19%), Positives = 176/419 (42%), Gaps = 67/419 (15%)
Query: 230 EDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCL----- 284
E + + +E D K ++ L + L + L + + + E ++++ K+++ + L
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDAR 303
Query: 285 -QERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREK-- 341
Y E+ + + +++ +S+ +E + ++ K +E+ LL+ +
Sbjct: 304 SARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTML 363
Query: 342 EAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQI 401
E Q + + ++ +LEKENL+ LK++L + E ER + K +I
Sbjct: 364 EDQLEGTRARSDKLHELEKENLQ----LKAKLHDM-----------EMERDMDRK---KI 405
Query: 402 NEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSP 461
E+ EN L+ +S + E+ L +LE++ ++T+ + P S
Sbjct: 406 EELMEENMTLEMAQKQSMD-------ESLHLGWELEQI--------SRTSELSEAPQKSL 450
Query: 462 CEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKS 521
E +N R +L + SL + L T D + +A + EK + + +K++
Sbjct: 451 GHE-VNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVE- 508
Query: 522 LHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQ 581
L+ E++ E +S+++ +L+++L E+ IE +
Sbjct: 509 ------ILENEIVQ----EKQSLQNC-----------QNLSKDLMKEKAQLEKTIETLRE 547
Query: 582 RLAISHSQIAHLEERNKHLEDLIRKPREKARKPRSKSLENHPKSMTMMPALFKENRNDL 640
S QI LE+ N+HL + R++++ +++ K ++ KE + L
Sbjct: 548 N---SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKL 603
Score = 48.9 bits (115), Expect = 1e-05
Identities = 97/462 (20%), Positives = 189/462 (40%), Gaps = 57/462 (12%)
Query: 1 MTEKPEFQSQVYNYAKDNNIKQDSFKEENPMETSVSANTDQLG--NEYFRQPPPRSPPLI 58
+ E + Q+ K ++ K+ E V ++ G N++ R+ + L+
Sbjct: 983 LEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELL 1042
Query: 59 HCSGEMLKFTEKSLAKSIAKESALNPSQPPSFLCKTAVPSKEIQNYG------EIPEMSV 112
+++ E++ A A++ AL KT + E QN + +V
Sbjct: 1043 KVKDRLIE-VERNNATLQAEKQAL----------KTQLKQLETQNNNLQAQILALQRQTV 1091
Query: 113 SYEKEVTAEGVERPEIV---STWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDM-- 167
S +++ T + ++ ST +S S ++ + + E ES+ +ED+
Sbjct: 1092 SLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKS 1151
Query: 168 ---ALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLK-- 222
+L + +KL+ + +Q + L + L+ K L+++ + + + K K
Sbjct: 1152 LYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQ 1211
Query: 223 -ENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRN----DKEMLQLQFKKI 277
E++E++++ + + +L +N +T+ + L L + + + E+LQ K +
Sbjct: 1212 LEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNL 1271
Query: 278 KA---NYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASAL 334
K+ N Q R E +K QY ++D T +K + E L QLK LE+ L
Sbjct: 1272 KSLLNNSKLEQTRLEAEF---SKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLL 1328
Query: 335 D----LLKREKEAQEQEFLSLQ----EEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFM 386
D L+ + + EQ S E+ Q ++K N RQK K EK++ Q +
Sbjct: 1329 DQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLE-EKIMDQYKFYDPS 1387
Query: 387 SENER--------TKNIKLQQQINEVKNENAKLKQQVARSEE 420
R K IK ++ IN + ++ L + S E
Sbjct: 1388 PPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSE 1429
Score = 34.7 bits (78), Expect = 0.28
Identities = 90/432 (20%), Positives = 171/432 (39%), Gaps = 65/432 (15%)
Query: 240 NDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEM--QQKNK 297
ND + NL ++ + + QE+ M+ L N + + + +E ++ K
Sbjct: 70 NDASLRMHNLSILVRQIKFYYQETLQQLIMMSLP------NVLIIGKNPFSEQGTEEVKK 123
Query: 298 SVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKE----AQEQEFLSL-Q 352
+ L KKEE +ER+Q L + + A A+ + + +E Q E + Q
Sbjct: 124 LLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQ 183
Query: 353 EEFQKLEKEN-------LEERQKLKSRLEKLLTQVRNLQFMSENERT----------KNI 395
E+ + L K ++ER + + +L + L F+ + K
Sbjct: 184 EDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRT 243
Query: 396 KLQQQIN-EVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDI-TKDTKTTHS 453
+ +Q ++ E+ + AK+++ EE +T QL D +E+ + +I K + +
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEE-------KTEQLLDCKQELEQMEIELKRLQQENM 296
Query: 454 NLLPDCSPCEERLNPADIKRASQL-ASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVS 512
NLL D + D R + K+ S ++ L + + E KE +V
Sbjct: 297 NLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVL 356
Query: 513 DIMLQKLKSLHLKKKTLDKEVID---CDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLV 569
L+ KT+ ++ ++ SD+ + L AKL H + E D
Sbjct: 357 -----------LETKTMLEDQLEGTRARSDKLHELEKENLQLKAKL---HDMEMERDMDR 402
Query: 570 TSYEEIIECADQRLAISHSQIAHLEERNKHLE---DLIRKPREKARKPRSKSLENHPKSM 626
EE++E + + + +Q ++E + HL + I + E + P+ KSL + +
Sbjct: 403 KKIEELME---ENMTLEMAQKQSMDE-SLHLGWELEQISRTSELSEAPQ-KSLGHEVNEL 457
Query: 627 TMMPALFKENRN 638
T L E N
Sbjct: 458 TSSRLLKLEMEN 469
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 85.5 bits (210), Expect = 1e-16
Identities = 104/508 (20%), Positives = 225/508 (44%), Gaps = 47/508 (9%)
Query: 152 DWEQSAESLQPVQED-MALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITK 210
D E+S +LQ +++ L LQ K Q+VR EL+ + + + + +
Sbjct: 1417 DSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476
Query: 211 QQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEML 270
+++ + KL+ + L+ + + + + + + + + + + LQ+ + +
Sbjct: 1477 EKLQRE---KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKD 1533
Query: 271 QLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQL-KKELEKA 329
+ K+K L+ + + ++ ++ +++ + E E+ER++Q KE+E
Sbjct: 1534 EASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESR 1593
Query: 330 TASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSEN 389
+ + ++ +Q + L+EE++ +K L E+++L+ +L L QV F SE
Sbjct: 1594 DEEVEEARQSCQKKLKQMEVQLEEEYEDKQKV-LREKRELEGKLATLSDQVNRRDFESEK 1652
Query: 390 ERTKNIK--------LQQQINEVKN------ENAKLKQQVARSE-------EQNYVPKFE 428
K++K Q ++ +KN E A+LK Q+ SE + + E
Sbjct: 1653 RLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVE 1712
Query: 429 TAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALM 488
L Q++++ K+ + + S L + + + RL D + ++L K + +A
Sbjct: 1713 IEDLHLQIDDIAKAKTALEEQL--SRLQREKNEIQNRLEE-DQEDMNELMKKHKAAVAQ- 1768
Query: 489 VGLLTCQDI--INSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCD--SDEAKSI 544
+D+ IN +E+ K + +KL++L + + L++ ++D S + I
Sbjct: 1769 ----ASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKI 1824
Query: 545 RDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLI 604
R++ T L + + L L + E++ E DQR+A + + +E+NK L+ +
Sbjct: 1825 RELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENRE----KEQNKRLQRQL 1880
Query: 605 RKPREK----ARKPRSKSLENHPKSMTM 628
R +E+ ARK S + H M +
Sbjct: 1881 RDTKEEMGELARKEAEASRKKHELEMDL 1908
Score = 67.8 bits (164), Expect = 3e-11
Identities = 62/250 (24%), Positives = 128/250 (51%), Gaps = 12/250 (4%)
Query: 198 EKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQ 257
++ + +L+ ++ + + K ++ +E IED + L+ +D K LEE L+ Q
Sbjct: 1682 KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLH---LQIDDIAKAKTALEEQLSRLQ 1738
Query: 258 KHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVE 317
+ E +N E Q ++ + + ++ Q N +Q E +K +K+E E
Sbjct: 1739 REKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANK---EKQELQE 1795
Query: 318 RLQQLKKELEKATASALD-LLKREKEAQEQEFLSLQEEFQKLEKENLEE-RQKLKSRLEK 375
+LQ L+ ++E S +D L +EA+ +E L + EF++ + + LE +LK +EK
Sbjct: 1796 KLQALQSQVEFLEQSMVDKSLVSRQEAKIRE-LETRLEFERTQVKRLESLASRLKENMEK 1854
Query: 376 LLTQVRNLQFMSEN-ERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKD 434
LT+ R+ + +EN E+ +N +LQ+Q+ + K E +L ++ A + + + + + L +
Sbjct: 1855 -LTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESL-E 1912
Query: 435 QLEEVLKSDI 444
+ L++D+
Sbjct: 1913 AANQSLQADL 1922
Score = 55.1 bits (131), Expect = 2e-07
Identities = 56/267 (20%), Positives = 123/267 (46%), Gaps = 22/267 (8%)
Query: 184 EVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTK 243
EV++ E Q N ++ +++L+ K+ K + N+L+ N + L ++ E D +
Sbjct: 1248 EVQLSEEQIRNK--DEEIQQLRSKLEKAE---KERNELRLNSDRLESRISELTSELTDER 1302
Query: 244 KTLQNLEEVL-ANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQY 302
T ++ ++L A T + L+ + KE LQ Q+ +K ++ M + ++
Sbjct: 1303 NTGESASQLLDAETAERLRAEKEMKE-LQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
Query: 303 LEMDKTLS----KKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKL 358
++ D K E V + KK L++ L++ ++ K E+ LQ +
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD---- 1417
Query: 359 EKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQ-------QINEVKNENAKL 411
+E+ Q+LK + ++L ++++ + E ++ +N +L++ ++++ E +
Sbjct: 1418 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQRE 1477
Query: 412 KQQVARSEEQNYVPKFETAQLKDQLEE 438
K Q + + + + E LK QLEE
Sbjct: 1478 KLQREKLQREKDMLLAEAFSLKQQLEE 1504
Score = 32.0 bits (71), Expect = 1.8
Identities = 54/245 (22%), Positives = 100/245 (40%), Gaps = 55/245 (22%)
Query: 199 KRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQK 258
+R L +TK+ ++ + VEEL+E + LEK+ L + A T
Sbjct: 1123 RRFDVLAPHLTKKHGRNYIVVDERRAVEELLEC---LDLEKSSCCMGLSRVF-FRAGTLA 1178
Query: 259 HLQESRNDKEMLQL--------------QFKKIKANYVCLQERYMTEMQQKNKSVSQY-- 302
L+E R+++ L FKK K + + R + + +KNK V +
Sbjct: 1179 RLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAI--RCVQKNIKKNKGVKDWPW 1236
Query: 303 ----------LEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLS-- 350
+E+ + + + E +QQL+ +LEKA EKE E S
Sbjct: 1237 WKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKA----------EKERNELRLNSDR 1286
Query: 351 LQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAK 410
L+ +L E +ER +S + L + E + ++ ++++ E++ +
Sbjct: 1287 LESRISELTSELTDERNTGESASQLL-----------DAETAERLRAEKEMKELQTQYDA 1335
Query: 411 LKQQV 415
LK+Q+
Sbjct: 1336 LKKQM 1340
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 85.5 bits (210), Expect = 1e-16
Identities = 104/508 (20%), Positives = 225/508 (44%), Gaps = 47/508 (9%)
Query: 152 DWEQSAESLQPVQED-MALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITK 210
D E+S +LQ +++ L LQ K Q+VR EL+ + + + + +
Sbjct: 1417 DSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476
Query: 211 QQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEML 270
+++ + KL+ + L+ + + + + + + + + + + LQ+ + +
Sbjct: 1477 EKLQRE---KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKD 1533
Query: 271 QLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQL-KKELEKA 329
+ K+K L+ + + ++ ++ +++ + E E+ER++Q KE+E
Sbjct: 1534 EASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESR 1593
Query: 330 TASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSEN 389
+ + ++ +Q + L+EE++ +K L E+++L+ +L L QV F SE
Sbjct: 1594 DEEVEEARQSCQKKLKQMEVQLEEEYEDKQKV-LREKRELEGKLATLSDQVNRRDFESEK 1652
Query: 390 ERTKNIK--------LQQQINEVKN------ENAKLKQQVARSE-------EQNYVPKFE 428
K++K Q ++ +KN E A+LK Q+ SE + + E
Sbjct: 1653 RLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVE 1712
Query: 429 TAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALM 488
L Q++++ K+ + + S L + + + RL D + ++L K + +A
Sbjct: 1713 IEDLHLQIDDIAKAKTALEEQL--SRLQREKNEIQNRLEE-DQEDMNELMKKHKAAVAQ- 1768
Query: 489 VGLLTCQDI--INSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCD--SDEAKSI 544
+D+ IN +E+ K + +KL++L + + L++ ++D S + I
Sbjct: 1769 ----ASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKI 1824
Query: 545 RDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLI 604
R++ T L + + L L + E++ E DQR+A + + +E+NK L+ +
Sbjct: 1825 RELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENRE----KEQNKRLQRQL 1880
Query: 605 RKPREK----ARKPRSKSLENHPKSMTM 628
R +E+ ARK S + H M +
Sbjct: 1881 RDTKEEMGELARKEAEASRKKHELEMDL 1908
Score = 67.8 bits (164), Expect = 3e-11
Identities = 62/250 (24%), Positives = 128/250 (51%), Gaps = 12/250 (4%)
Query: 198 EKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQ 257
++ + +L+ ++ + + K ++ +E IED + L+ +D K LEE L+ Q
Sbjct: 1682 KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLH---LQIDDIAKAKTALEEQLSRLQ 1738
Query: 258 KHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVE 317
+ E +N E Q ++ + + ++ Q N +Q E +K +K+E E
Sbjct: 1739 REKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANK---EKQELQE 1795
Query: 318 RLQQLKKELEKATASALD-LLKREKEAQEQEFLSLQEEFQKLEKENLEE-RQKLKSRLEK 375
+LQ L+ ++E S +D L +EA+ +E L + EF++ + + LE +LK +EK
Sbjct: 1796 KLQALQSQVEFLEQSMVDKSLVSRQEAKIRE-LETRLEFERTQVKRLESLASRLKENMEK 1854
Query: 376 LLTQVRNLQFMSEN-ERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKD 434
LT+ R+ + +EN E+ +N +LQ+Q+ + K E +L ++ A + + + + + L +
Sbjct: 1855 -LTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESL-E 1912
Query: 435 QLEEVLKSDI 444
+ L++D+
Sbjct: 1913 AANQSLQADL 1922
Score = 55.1 bits (131), Expect = 2e-07
Identities = 56/267 (20%), Positives = 123/267 (46%), Gaps = 22/267 (8%)
Query: 184 EVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTK 243
EV++ E Q N ++ +++L+ K+ K + N+L+ N + L ++ E D +
Sbjct: 1248 EVQLSEEQIRNK--DEEIQQLRSKLEKAE---KERNELRLNSDRLESRISELTSELTDER 1302
Query: 244 KTLQNLEEVL-ANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQY 302
T ++ ++L A T + L+ + KE LQ Q+ +K ++ M + ++
Sbjct: 1303 NTGESASQLLDAETAERLRAEKEMKE-LQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
Query: 303 LEMDKTLS----KKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKL 358
++ D K E V + KK L++ L++ ++ K E+ LQ +
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD---- 1417
Query: 359 EKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQ-------QINEVKNENAKL 411
+E+ Q+LK + ++L ++++ + E ++ +N +L++ ++++ E +
Sbjct: 1418 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQRE 1477
Query: 412 KQQVARSEEQNYVPKFETAQLKDQLEE 438
K Q + + + + E LK QLEE
Sbjct: 1478 KLQREKLQREKDMLLAEAFSLKQQLEE 1504
Score = 32.0 bits (71), Expect = 1.8
Identities = 54/245 (22%), Positives = 100/245 (40%), Gaps = 55/245 (22%)
Query: 199 KRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQK 258
+R L +TK+ ++ + VEEL+E + LEK+ L + A T
Sbjct: 1123 RRFDVLAPHLTKKHGRNYIVVDERRAVEELLEC---LDLEKSSCCMGLSRVF-FRAGTLA 1178
Query: 259 HLQESRNDKEMLQL--------------QFKKIKANYVCLQERYMTEMQQKNKSVSQY-- 302
L+E R+++ L FKK K + + R + + +KNK V +
Sbjct: 1179 RLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAI--RCVQKNIKKNKGVKDWPW 1236
Query: 303 ----------LEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLS-- 350
+E+ + + + E +QQL+ +LEKA EKE E S
Sbjct: 1237 WKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKA----------EKERNELRLNSDR 1286
Query: 351 LQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAK 410
L+ +L E +ER +S + L + E + ++ ++++ E++ +
Sbjct: 1287 LESRISELTSELTDERNTGESASQLL-----------DAETAERLRAEKEMKELQTQYDA 1335
Query: 411 LKQQV 415
LK+Q+
Sbjct: 1336 LKKQM 1340
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 85.1 bits (209), Expect = 2e-16
Identities = 114/549 (20%), Positives = 245/549 (44%), Gaps = 91/549 (16%)
Query: 153 WEQSAESLQPVQEDM-ALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQ 211
+E +E L+ VQE M AL L + +H N K + + +L+ + +++ ++ TKQ
Sbjct: 712 FEAISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQ 771
Query: 212 QV-FIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEM- 269
Q + +N L++ ++E + E +D + L + ++ L++ + + ++E
Sbjct: 772 QEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKE 831
Query: 270 -----------------LQLQFKKIKANYVCLQERY-------MTEMQQKNKSVSQYLEM 305
L+L+ +K+ + CLQ+ Y E+ Q ++++ + +
Sbjct: 832 FNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKE 891
Query: 306 DKTL------------SKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQE 353
++TL ++KE + Q +++ E ++ L +L+ ++ +++E ++
Sbjct: 892 NETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQ 951
Query: 354 EFQKLEK--ENLEERQKLKSRLEK-----------LLTQVRNLQFMSENERTKNIKLQQQ 400
+ K++K E+L +K+ S LEK L+ Q++ L+ S E+T+ I +Q
Sbjct: 952 QMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELR-TSVCEKTETIDTLKQ 1010
Query: 401 INEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLE----EVLKSDITKDTKTTHSNLL 456
E+K+ N K + EE + K + + D E +L DI +D L
Sbjct: 1011 --ELKDINCKYNSALVDREESRVLIKKQEVDILDLKETLRLRILSEDIERDM------LC 1062
Query: 457 PDCSPCEERLNPADIKRASQLASKMHS-LLALMVGLLTCQDIINSDAEHFKESEKVSDIM 515
D + E+LN ASK HS LL LT ++ + + +H K ++K ++
Sbjct: 1063 EDLAHATEQLN------MLTEASKKHSGLLQSAQEELTKKEALIQELQH-KLNQKKEEVE 1115
Query: 516 LQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVP---TLLGAKLDKYHSLNEELDFLVTSY 572
QK + K + L+ V+D +++ +S + P T L L+ E+ TS
Sbjct: 1116 -QKKNEYNFKMRQLE-HVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSL 1173
Query: 573 EEIIECADQRLAISHSQIAHLEERNKHLED-------------LIRKPREKARKPRSKSL 619
E ++ ++ + +++I ++E+ + +E+ L++ + ++ + S
Sbjct: 1174 EHLVTKLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENSD 1233
Query: 620 ENHPKSMTM 628
+NHP + +
Sbjct: 1234 QNHPDNQQL 1242
Score = 55.5 bits (132), Expect = 2e-07
Identities = 105/485 (21%), Positives = 198/485 (40%), Gaps = 71/485 (14%)
Query: 170 NEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKEL---QMKITKQQVFIDVINK---LKE 223
N L+ L+ R QE+ Q + LEK E+ + QQ F K L
Sbjct: 524 NRRLRLLEPVKRAQEMDAQTIA----KLEKAFSEISGMEKSDKNQQGFSPKAQKEPCLFA 579
Query: 224 NVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKI-KANYV 282
N E+L +I E N++K+ + +E+ Q L+ + L + + +A
Sbjct: 580 NTEKLKAQLLQIQTELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLENLLEATKA 639
Query: 283 CLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVER-LQQLKKEL--------EKATASA 333
C ++ E+ Q NK ++ L++ T +K + R + +L E+ + ++
Sbjct: 640 CKRQ----EVSQLNKIHAETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNSSILD 695
Query: 334 LDLLKRE--KEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENER 391
D+L E EQ F ++ EE + +++ Q+ LQ + E
Sbjct: 696 NDILNEPVPPEMNEQAFEAISEELRTVQE------------------QMSALQAKLDEEE 737
Query: 392 TKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTT 451
KN+KLQQ ++++++ + ++ Q++ SE ++ + E +L QL + K ++T+T
Sbjct: 738 HKNLKLQQHVDKLEHHSTQM-QELFSSERIDWTKQQE--ELLSQLNVLEKQ--LQETQTK 792
Query: 452 HSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKV 511
+ L + L+ AD K S + + S N + E K SE+
Sbjct: 793 NDFLKSEVHDLRVVLHSAD-KELSSVKLEYSSFKT------------NQEKEFNKLSERH 839
Query: 512 SDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTL----LGAKLDKYHSLNEELDF 567
+ LQ L +L L+ + L E C D +++++ L L + NE L
Sbjct: 840 MHVQLQ-LDNLRLENEKL-LESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKS 897
Query: 568 LVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKPREKARKPRSKSLENHPKSMT 627
+ + E++E +R ++ EE ++ I K E R+ + K + M
Sbjct: 898 DLNNLMELLEAEKER---NNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMA 954
Query: 628 MMPAL 632
+ L
Sbjct: 955 KVQKL 959
Score = 50.8 bits (120), Expect = 4e-06
Identities = 63/315 (20%), Positives = 144/315 (45%), Gaps = 35/315 (11%)
Query: 169 LNEVLQKLKHTNRKQEVRIQELQCSNLYLEKR------VKE-LQMKITKQQVFIDVINKL 221
++ + Q+LK N K + + + S + ++K+ +KE L+++I + + D+ L
Sbjct: 1005 IDTLKQELKDINCKYNSALVDREESRVLIKKQEVDILDLKETLRLRILSEDIERDM---L 1061
Query: 222 KENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRN--DKEMLQLQFKKIKA 279
E++ E + LQ+ +E L + +QE ++ +++ +++ KK +
Sbjct: 1062 CEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEY 1121
Query: 280 NYVCLQERYM----TEMQQKNKSVSQY-LEMDKTLSKKEEEVERLQQLKKELEKATASAL 334
N+ Q ++ E Q K+ + + K L +E+E+E + K LE
Sbjct: 1122 NFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTK-- 1179
Query: 335 DLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSR--LEKLLTQVRNLQFMSE---- 388
L ++E + E L ++E+ +++E LE +Q ++ L+ L ++ + S+
Sbjct: 1180 --LNEDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHP 1237
Query: 389 ------NERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLE--EVL 440
NE+ ++IK + +++ E K+K + + Y + E ++ D++E + L
Sbjct: 1238 DNQQLKNEQEESIKERLAKSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTL 1297
Query: 441 KSDITKDTKTTHSNL 455
+S ++ + S L
Sbjct: 1298 ESKAFQEKEQLRSKL 1312
Score = 45.8 bits (107), Expect = 1e-04
Identities = 59/281 (20%), Positives = 127/281 (45%), Gaps = 41/281 (14%)
Query: 154 EQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQ-------M 206
+ +AE Q + L KL T QE I++ + S LE V +L
Sbjct: 1133 DSAAEDPQSPKTPPHFQTHLAKLLET---QEQEIEDGRASKTSLEHLVTKLNEDREVKNA 1189
Query: 207 KITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEE------VLANTQKHL 260
+I + + + + L+ ++LIE + + + +D K+ +N ++ L N Q+
Sbjct: 1190 EILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEES 1249
Query: 261 QESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQ 320
+ R K + + K+KA+ L+E ++ + + E+++T + + + + +
Sbjct: 1250 IKERLAKSKIVEEMLKMKAD---LEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKE 1306
Query: 321 QLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKEN--LEERQKLKSRLEKLLT 378
QL+ +LE+ + E+E QE L+++ + L +EN L Q L +++ ++
Sbjct: 1307 QLRSKLEE--------MYEERERTSQEMEMLRKQVECLAEENGKLVGHQNLHQKIQYVV- 1357
Query: 379 QVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSE 419
+ +N++L ++ +++ EN LK++ RSE
Sbjct: 1358 ----------RLKKENVRLAEETEKLRAENVFLKEK-KRSE 1387
Score = 40.0 bits (92), Expect = 0.007
Identities = 64/319 (20%), Positives = 136/319 (42%), Gaps = 43/319 (13%)
Query: 244 KTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYL 303
K ++N V +TQ ++ + + + + L+ Q ++ + E ++T ++K + +
Sbjct: 361 KLIKNKAVVNEDTQGNVSQLQAEVKRLKEQLAELASGQTP-PESFLTRDKKKTNYMEYFQ 419
Query: 304 EMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENL 363
E K E+E + L +EK T LK+EK Q + + E Q + E L
Sbjct: 420 EAMLFFKKSEQEKKSL------IEKVTQLEDLTLKKEKFIQSNKMIVKFREDQIIRLEKL 473
Query: 364 EERQK---LKSRLEKLLTQVRN-LQFMSE--NERTKNIKLQQQINEVKNENAKLK--QQV 415
+ + L ++LL+++RN +Q + E + K + + ++ EN +L+ + V
Sbjct: 474 HKESRGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRRLRLLEPV 533
Query: 416 ARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRAS 475
R++E + AQ +LE+ S+I+ K+ + ++ +P K
Sbjct: 534 KRAQEMD-------AQTIAKLEKAF-SEISGMEKSDKN---------QQGFSPKAQKEPC 576
Query: 476 QLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVS-------DIMLQKLKSLHLKKKT 528
A+ L LL Q +N+ + ++E ++++ + LQ L+ +L +
Sbjct: 577 LFANTE----KLKAQLLQIQTELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLEN 632
Query: 529 LDKEVIDCDSDEAKSIRDV 547
L + C E + +
Sbjct: 633 LLEATKACKRQEVSQLNKI 651
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 84.7 bits (208), Expect = 2e-16
Identities = 120/533 (22%), Positives = 228/533 (42%), Gaps = 86/533 (16%)
Query: 157 AESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKE-------LQMKIT 209
AE LQ ++ A E+ + + + + QEL+ LE RV+E LQ +
Sbjct: 880 AEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKK 939
Query: 210 KQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEM 269
K Q I +L+E +EE + K+ LEK T+ L+ LEE + + +K++
Sbjct: 940 KMQ---QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKL 996
Query: 270 LQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKA 329
L+ + + N +E+ + + KNK + ++++ L ++E++ + L++ +++LE
Sbjct: 997 LEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGD 1056
Query: 330 TASALDL----------LKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQ 379
+ D LK + +E+E LQ ++E+E ++ LK ++ +L +Q
Sbjct: 1057 STDLSDQIAELQAQIAELKMQLAKKEEE---LQAALARVEEEAAQKNMALK-KIRELESQ 1112
Query: 380 VRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQV-------ARSEEQNYVPKFETAQL 432
+ LQ E+ER K ++Q ++ E LK ++ A +E + E L
Sbjct: 1113 ISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNIL 1172
Query: 433 KDQLEEVLKSDIT--KDTKTTHSNLLPDCSPCEERLN--PADIKRASQLASKMHSLLALM 488
K LEE K+ ++ + HS + + + E+ A++++A Q LA
Sbjct: 1173 KKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANE 1232
Query: 489 VGLLTCQDIINSDAEH---------------FKESEKVSDIMLQKLKSLHLKKKTLDKEV 533
V +L D+EH F E E+V + K+ L ++ + +
Sbjct: 1233 VKVLLQG---KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLL 1289
Query: 534 IDCDSDEAKSIRDVPTL--------------------LGAKL----DKYHSLNEELDFLV 569
DS +K +D L L KL D+ +S E+L+
Sbjct: 1290 SQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE--- 1346
Query: 570 TSYEEIIECADQRLAISHSQIAHLEERNKHLEDLI--RKPREKARKPRSKSLE 620
EE ++++A H+Q+A ++ K +ED + + E+ ++ K LE
Sbjct: 1347 -EEEEAKHNLEKQIATLHAQVADMK---KKMEDSVGCLETAEEVKRKLQKDLE 1395
Score = 67.4 bits (163), Expect = 4e-11
Identities = 101/499 (20%), Positives = 210/499 (42%), Gaps = 65/499 (13%)
Query: 154 EQSAESLQPVQEDMALNEVLQKLK------HTNRKQEVRIQELQCSNLYLEKRVKELQMK 207
E++ ++L+ + ++A NEV L+ H +K E ++QELQ E+ EL K
Sbjct: 1216 EKAKQTLENERGELA-NEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274
Query: 208 ITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDK 267
+TK QV +D + L + + + K LE L +TQ+ LQE K
Sbjct: 1275 VTKLQVELDNVTGLLSQSDS----------KSSKLTKDFSALESQLQDTQELLQEENRQK 1324
Query: 268 EMLQLQFKKIKANYVCLQERYMTEMQQKN---KSV----SQYLEMDKTLSKKEEEVERLQ 320
L + K+++ +E+ E + K+ K + +Q +M K + +E +
Sbjct: 1325 LSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAE 1384
Query: 321 QLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQV 380
++K++L+K + E Q + KLEK + +L+ L+ LL +
Sbjct: 1385 EVKRKLQK-----------DLEGLSQRHEEKVAAYDKLEK----TKTRLQQELDDLLVDL 1429
Query: 381 RNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVL 440
+ + + N K K Q + E K +AK ++ R+E + + + L LEE +
Sbjct: 1430 DHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Query: 441 --KSDITKDTKTTHSNLLPDCSPCEERLNPADI--KRASQLASKMHSLLALMVGLLTCQD 496
K+++ + K + + E+ ++ D K +L +L + + T +
Sbjct: 1490 EQKAELERLNKQFRTEM-------EDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLE 1542
Query: 497 IINSDAEHFKESEKVSDIMLQKLKS------------LHLKKKTLDKEV--IDCDSDEAK 542
+ + + ++++ ++ LQ +K+ KKK L ++V ++ + ++ +
Sbjct: 1543 ELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDER 1602
Query: 543 SIRDVPTLLGAKLD-KYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLE 601
R + KL+ L +D + +E I+ + A + L++ E
Sbjct: 1603 KQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASRE 1662
Query: 602 DLIRKPREKARKPRSKSLE 620
+++ + +E +K +S E
Sbjct: 1663 EILAQAKENEKKLKSMEAE 1681
Score = 60.1 bits (144), Expect = 6e-09
Identities = 91/446 (20%), Positives = 188/446 (42%), Gaps = 69/446 (15%)
Query: 127 EIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVR 186
++++ + + E R E + E A SL E+ E +L+ N++
Sbjct: 1448 QLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM--EQKAELERLNKQFRTE 1505
Query: 187 IQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTL 246
+++L S + K V EL+ ++ + ++K +EEL ++ + D K L
Sbjct: 1506 MEDLMSSKDDVGKSVHELEKS---KRALEQQVEEMKTQLEELEDE----LQATEDAKLRL 1558
Query: 247 Q-NLEEVLANTQKHLQ----ESRNDKEMLQLQFKKIKANY--------VCLQERYMTEMQ 293
+ NL+ + A ++ LQ +S K+ L Q ++++A + + R EM
Sbjct: 1559 EVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMD 1618
Query: 294 QKNKSVSQYLEMDKTLSKKEEEVERLQQLK-------KELEKATASALDLLKREKE---- 342
K+ +D ++E +++L++L+ +EL+ AS ++L + KE
Sbjct: 1619 LKDLEA----HIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKK 1674
Query: 343 --AQEQEFLSLQEEFQKLEKEN------------------------LEERQKLKSRLEKL 376
+ E E + LQEE E+ LEE+++L++R+ +L
Sbjct: 1675 LKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQL 1734
Query: 377 LTQVRNLQFMSE--NERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKD 434
++ Q +E N+R K L QI+++ + + ++E + + +LK
Sbjct: 1735 EEELEEEQGNTELINDRLKKANL--QIDQINTDLNLERSHAQKNENARQQLERQNKELKV 1792
Query: 435 QLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTC 494
+L+E ++ + K + + L + EE+L+ +R + + L LL
Sbjct: 1793 KLQE-MEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQV 1851
Query: 495 QDIINSDAEHFKESEKVSDIMLQKLK 520
D +AE +K+ + L++LK
Sbjct: 1852 DD-ERRNAEQYKDQADKASTRLKQLK 1876
Score = 46.6 bits (109), Expect = 7e-05
Identities = 52/296 (17%), Positives = 128/296 (43%), Gaps = 30/296 (10%)
Query: 154 EQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQV 213
+++ + L+ +Q M + +++L T +E E+ EK++K ++ ++ + Q
Sbjct: 1634 DEAIKQLRKLQAQM--KDCMRELDDTRASRE----EILAQAKENEKKLKSMEAEMIQLQE 1687
Query: 214 FIDVINKLKENVEELIEDKYKIILEKNDTKKTL-----QNLEEVLANTQKHLQESRNDKE 268
+ + K ++ D+ + + K L + LE +A ++ L+E + + E
Sbjct: 1688 ELAAAERAKRQAQQE-RDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 269 MLQLQFKK--IKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKEL 326
++ + KK ++ + + QKN++ Q LE ++LK +L
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQN------------KELKVKL 1794
Query: 327 EKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFM 386
++ + K A E + L+E+ KE RQ ++ + +++++
Sbjct: 1795 QEMEGTVKSKYKASITALEAKIAQLEEQLDNETKE----RQAACKQVRRTEKKLKDVLLQ 1850
Query: 387 SENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKS 442
++ER + + Q ++ +LK+Q+ +EE+ +L+ +LE+ ++
Sbjct: 1851 VDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATET 1906
Score = 29.6 bits (65), Expect = 8.9
Identities = 54/264 (20%), Positives = 100/264 (37%), Gaps = 58/264 (21%)
Query: 344 QEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINE 403
QE+E ++ +EE K+ ++ L E LT++ LQ E+ ++LQ+Q+
Sbjct: 843 QEEEMMAKEEELVKVREKQLAA--------ENRLTEMETLQSQLMAEK---LQLQEQLQA 891
Query: 404 VKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCE 463
A+ ++ AR + K +LEE+ C E
Sbjct: 892 ETELCAEAEELRARLTAK-----------KQELEEI-------------------CHDLE 921
Query: 464 ERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKV-SDIMLQKLKSL 522
R+ + +R L ++ + Q I E +E E + L+K+ +
Sbjct: 922 ARVEEEE-ERCQHLQAEKKKM----------QQNIQELEEQLEEEESARQKLQLEKVTTE 970
Query: 523 HLKKKTLDKEVIDCDSD-----EAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIE 577
KK ++++I D + E K + D L + ++ L L +E +I
Sbjct: 971 AKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMIT 1030
Query: 578 CADQRLAISHSQIAHLEERNKHLE 601
++RL Q LE+ + LE
Sbjct: 1031 DLEERLRREEKQRQELEKTRRKLE 1054
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 84.0 bits (206), Expect = 4e-16
Identities = 131/566 (23%), Positives = 237/566 (41%), Gaps = 128/566 (22%)
Query: 149 EMPDWEQSAESLQPVQEDMALNEV-LQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMK 207
E+ D E ++LQ E++ ++ L++L+ N+ E +L+ LEK K L+ +
Sbjct: 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Query: 208 I-----TKQQVFIDVINKLKEN----------------VEELIEDKYKIILEKNDTKKTL 246
T ++ + + N KEN ++EL ++ +++ KTL
Sbjct: 845 AEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTL 904
Query: 247 QNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKN---KSVSQYL 303
L E L + + Q+ ND E L + +KI N +ER + + Q + K + L
Sbjct: 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLN----KERLLHDEQSTDDRYKLLESKL 960
Query: 304 E--MDKTLSKKEEEVERL-----------QQLKKELEKATASALDLLKR----------- 339
E + K+L KEE++ L QQL++EL+ + L +R
Sbjct: 961 ESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSP 1020
Query: 340 ---------EKEAQE--QEFLSLQEEFQKLEKENLE---ERQKLKSRLEKLLTQVRNLQF 385
E+E+QE +E L +++ ++E+ N E+Q LK++L++L TQ NLQ
Sbjct: 1021 PISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA 1080
Query: 386 MSENERTKNIKLQQQINEVKNENAKLK-------QQVARSEEQNYVPKFETAQLKDQLEE 438
+ + + LQ+Q ++ +NAKL+ Q QN + + L+++ E
Sbjct: 1081 QILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENES 1140
Query: 439 VLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQ---LASKMHSLLALMVGL-LTC 494
V+K +D K+ + +L+ D E+L ++AS+ L SK +L + L +
Sbjct: 1141 VIKE--REDLKSLYDSLIKD----HEKLELLHERQASEYESLISKHGTLKSAHKNLEVEH 1194
Query: 495 QDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDK----------------------- 531
+D+ + + K+ ++ D L+K+ + +K L+
Sbjct: 1195 RDLEDRYNQLLKQKGQLED--LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHT 1252
Query: 532 --------EVIDCDSDEAKSIRD----VPTLLGAKLDKYHSLNEELDFLVTSYEEIIECA 579
EV+ D KS+ + T L A+ K ++LD T E
Sbjct: 1253 YSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELL 1312
Query: 580 DQRLAISHSQIAHLEERNKHLEDLIR 605
Q +LEE N+HL D I+
Sbjct: 1313 SQLK-------GNLEEENRHLLDQIQ 1331
Score = 76.6 bits (187), Expect = 6e-14
Identities = 106/430 (24%), Positives = 202/430 (46%), Gaps = 50/430 (11%)
Query: 171 EVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIE 230
++ ++L+H K E R +EL+ +LEK + LQ KIT ++ + I L++ EL
Sbjct: 612 QIKKELEHYKEKGE-RAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELER 670
Query: 231 DKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMT 290
+ K+ T + +NL L + +K + S+ D+E L+L ++ + C + M
Sbjct: 671 ENRKL----KKTLDSFKNLTFQLESLEK--ENSQLDEENLEL--RRNVESLKCASMK-MA 721
Query: 291 EMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDL----LKREKEAQEQ 346
++Q +NK LE +K KK E+ + K E + + LD+ L++ E +
Sbjct: 722 QLQLENKE----LESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNK 777
Query: 347 EFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKN 406
+ L+ E Q LE EN Q L+ LE+L + L+ + + +N L+Q+ ++++
Sbjct: 778 KIQQLESELQDLEMEN----QTLQKNLEELKISSKRLEQLEK----ENKSLEQETSQLEK 829
Query: 407 ENAKLKQQVARSEEQNYVPKFETAQLKD-QLEE--VLKSDITKDTKTTHSNLLPDCSPCE 463
+ +L+++ R +Q A++KD LEE V ++ K+ KT + C
Sbjct: 830 DKKQLEKENKRLRQQ--------AEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCV 881
Query: 464 -----ERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQK 518
E+ N +KRA+ + +L +V +N+D E K + ++ I L K
Sbjct: 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE--KLTHELEKIGLNK 939
Query: 519 LKSLHLKKKTLDKEVI---DCDSDEAKSI---RDVPTLLGAKLDKYHSLNEELDFLVTSY 572
+ LH ++ T D+ + +S KS+ + L A+L++ + N++L + +
Sbjct: 940 ERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTV 999
Query: 573 EEIIECADQR 582
++ E QR
Sbjct: 1000 KKNYEALKQR 1009
Score = 67.8 bits (164), Expect = 3e-11
Identities = 103/532 (19%), Positives = 235/532 (44%), Gaps = 73/532 (13%)
Query: 141 SEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLK-------HTNRKQEVRIQELQCS 193
SE R + D E ++ ++ED N+VL + K R + ++ EL+
Sbjct: 327 SEVSRYKERLHDIEFYKARVEELKED---NQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Query: 194 NLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVL 253
NL L+ ++ +++M+ ++ +EEL+E+ + + + Q+++E L
Sbjct: 384 NLQLKAKLHDMEMERDMD----------RKKIEELMEENMTLEMAQK------QSMDESL 427
Query: 254 ANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLE-MDKTLSKK 312
+ L++ E+ + K + L + +++ +N+S+++ +E + T+
Sbjct: 428 -HLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSV 486
Query: 313 EEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSR 372
E ++ +++KE ++ + +++L+ E ++Q + Q + L KE + + +++
Sbjct: 487 EGNASKILKMEKENQRLSKK-VEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETL 545
Query: 373 LEKLLTQVRNLQFMSE--NERTKNIKLQQQIN------EVKNENAKLKQQVARSEEQNYV 424
E Q++ L+ +E N+ +++ + QI+ +++ EN L + + + +
Sbjct: 546 RENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSK 605
Query: 425 PKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSL 484
+FE Q+K +LE + E L+ +++ ++L K +
Sbjct: 606 IEFEKRQIKKELEHYKEKG-------------ERAEELENELH--HLEKENELLQKKITN 650
Query: 485 LALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSI 544
L + + + NS+ E +E+ K+ L K+L + ++L+KE D + +
Sbjct: 651 LKITCEKIEALEQENSELE--RENRKLKK-TLDSFKNLTFQLESLEKENSQLDEENLELR 707
Query: 545 RDVPTLLGAKL-------------DKYHSLNEELDFLVTSYE--EIIECADQRLAISHSQ 589
R+V +L A + + L + L+ L S++ E +E + Q L I + +
Sbjct: 708 RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQR 767
Query: 590 IAH-LEERNKHLEDLIRKPR--EKARKPRSKSLENHPKSMTMMPALFKENRN 638
+ LE NK ++ L + + E + K+LE S + L KEN++
Sbjct: 768 LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKS 819
Score = 53.5 bits (127), Expect = 6e-07
Identities = 81/419 (19%), Positives = 176/419 (42%), Gaps = 67/419 (15%)
Query: 230 EDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCL----- 284
E + + +E D K ++ L + L + L + + + E ++++ K+++ + L
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDAR 303
Query: 285 -QERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREK-- 341
Y E+ + + +++ +S+ +E + ++ K +E+ LL+ +
Sbjct: 304 SARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTML 363
Query: 342 EAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQI 401
E Q + + ++ +LEKENL+ LK++L + E ER + K +I
Sbjct: 364 EDQLEGTRARSDKLHELEKENLQ----LKAKLHDM-----------EMERDMDRK---KI 405
Query: 402 NEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSP 461
E+ EN L+ +S + E+ L +LE++ ++T+ + P S
Sbjct: 406 EELMEENMTLEMAQKQSMD-------ESLHLGWELEQI--------SRTSELSEAPQKSL 450
Query: 462 CEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKS 521
E +N R +L + SL + L T D + +A + EK + + +K++
Sbjct: 451 GHE-VNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVE- 508
Query: 522 LHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQ 581
L+ E++ E +S+++ +L+++L E+ IE +
Sbjct: 509 ------ILENEIVQ----EKQSLQNC-----------QNLSKDLMKEKAQLEKTIETLRE 547
Query: 582 RLAISHSQIAHLEERNKHLEDLIRKPREKARKPRSKSLENHPKSMTMMPALFKENRNDL 640
S QI LE+ N+HL + R++++ +++ K ++ KE + L
Sbjct: 548 N---SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKL 603
Score = 48.9 bits (115), Expect = 1e-05
Identities = 97/462 (20%), Positives = 189/462 (40%), Gaps = 57/462 (12%)
Query: 1 MTEKPEFQSQVYNYAKDNNIKQDSFKEENPMETSVSANTDQLG--NEYFRQPPPRSPPLI 58
+ E + Q+ K ++ K+ E V ++ G N++ R+ + L+
Sbjct: 982 LEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELL 1041
Query: 59 HCSGEMLKFTEKSLAKSIAKESALNPSQPPSFLCKTAVPSKEIQNYG------EIPEMSV 112
+++ E++ A A++ AL KT + E QN + +V
Sbjct: 1042 KVKDRLIE-VERNNATLQAEKQAL----------KTQLKQLETQNNNLQAQILALQRQTV 1090
Query: 113 SYEKEVTAEGVERPEIV---STWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDM-- 167
S +++ T + ++ ST +S S ++ + + E ES+ +ED+
Sbjct: 1091 SLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKS 1150
Query: 168 ---ALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLK-- 222
+L + +KL+ + +Q + L + L+ K L+++ + + + K K
Sbjct: 1151 LYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQ 1210
Query: 223 -ENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRN----DKEMLQLQFKKI 277
E++E++++ + + +L +N +T+ + L L + + + E+LQ K +
Sbjct: 1211 LEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNL 1270
Query: 278 KA---NYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASAL 334
K+ N Q R E +K QY ++D T +K + E L QLK LE+ L
Sbjct: 1271 KSLLNNSKLEQTRLEAEF---SKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLL 1327
Query: 335 D----LLKREKEAQEQEFLSLQ----EEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFM 386
D L+ + + EQ S E+ Q ++K N RQK K EK++ Q +
Sbjct: 1328 DQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLE-EKIMDQYKFYDPS 1386
Query: 387 SENER--------TKNIKLQQQINEVKNENAKLKQQVARSEE 420
R K IK ++ IN + ++ L + S E
Sbjct: 1387 PPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSE 1428
Score = 34.7 bits (78), Expect = 0.28
Identities = 90/432 (20%), Positives = 171/432 (39%), Gaps = 65/432 (15%)
Query: 240 NDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEM--QQKNK 297
ND + NL ++ + + QE+ M+ L N + + + +E ++ K
Sbjct: 70 NDASLRMHNLSILVRQIKFYYQETLQQLIMMSLP------NVLIIGKNPFSEQGTEEVKK 123
Query: 298 SVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKE----AQEQEFLSL-Q 352
+ L KKEE +ER+Q L + + A A+ + + +E Q E + Q
Sbjct: 124 LLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQ 183
Query: 353 EEFQKLEKEN-------LEERQKLKSRLEKLLTQVRNLQFMSENERT----------KNI 395
E+ + L K ++ER + + +L + L F+ + K
Sbjct: 184 EDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRT 243
Query: 396 KLQQQIN-EVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDI-TKDTKTTHS 453
+ +Q ++ E+ + AK+++ EE +T QL D +E+ + +I K + +
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEE-------KTEQLLDCKQELEQMEIELKRLQQENM 296
Query: 454 NLLPDCSPCEERLNPADIKRASQL-ASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVS 512
NLL D + D R + K+ S ++ L + + E KE +V
Sbjct: 297 NLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVL 356
Query: 513 DIMLQKLKSLHLKKKTLDKEVID---CDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLV 569
L+ KT+ ++ ++ SD+ + L AKL H + E D
Sbjct: 357 -----------LETKTMLEDQLEGTRARSDKLHELEKENLQLKAKL---HDMEMERDMDR 402
Query: 570 TSYEEIIECADQRLAISHSQIAHLEERNKHLE---DLIRKPREKARKPRSKSLENHPKSM 626
EE++E + + + +Q ++E + HL + I + E + P+ KSL + +
Sbjct: 403 KKIEELME---ENMTLEMAQKQSMDE-SLHLGWELEQISRTSELSEAPQ-KSLGHEVNEL 457
Query: 627 TMMPALFKENRN 638
T L E N
Sbjct: 458 TSSRLLKLEMEN 469
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 80.5 bits (197), Expect = 4e-15
Identities = 134/642 (20%), Positives = 267/642 (41%), Gaps = 81/642 (12%)
Query: 21 KQDSFKEENPMETSVSANTDQLGNEYFRQPPPRSPPLIHCSGEMLKFTEKSLAKSIAKES 80
KQ E E+ V+ QL N +Q L C E+ E+S + + +
Sbjct: 83 KQKISHELQVKESQVNFQEGQL-NSGKKQIEKLEQELKRCKSEL----ERSQQAAQSADV 137
Query: 81 ALNPSQPPSFLCKTAVPSKEIQNYGEIPEMSVSYEKEVTAEGVERPEIVSTWSSAGISWR 140
+LNP P + T + + + + ++ Y KEV E+ + +
Sbjct: 138 SLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTL 197
Query: 141 SEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRI------QELQCSN 194
+A + ++ Q++ S+ Q++ + + + T +++ QE+ S
Sbjct: 198 PQATMNHRDIAR-HQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQEVTPSR 256
Query: 195 LYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLA 254
L+ ++ ++++LK +EL + + LE L
Sbjct: 257 STLQIGKRDANSSFFDNSSSPHLLDQLKAQNQEL--------------RNKINELELRLQ 302
Query: 255 NTQKHLQESRNDKEMLQLQFKKIKANYV--------CLQERYMTEMQQKNKSVSQYLEMD 306
+K ++ N + LQLQ +K K + C E T Q S ++Y ++
Sbjct: 303 GHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQAS-TKYTALE 361
Query: 307 KTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQE-EFQKLEKENLEE 365
+ L K E++ +++ ++ +L+ +EKE + QE LS Q+ FQ L++E ++
Sbjct: 362 QKLKKLTEDL----SCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQ- 416
Query: 366 RQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVP 425
+K+RL + L Q +N+ + + E K ++QQ+ +N + KQ++ R+E+
Sbjct: 417 ---MKARLTQELQQAKNMHNVLQAELDKLTSVKQQL---ENNLEEFKQKLCRAEQAFQAS 470
Query: 426 KFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEER---LNPADIKRASQLASKMH 482
+ + +L+ +EE+ K +NLL S + R A++K Q ++
Sbjct: 471 QIKENELRRSMEEMKK----------ENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQ 520
Query: 483 SLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAK 542
+ M T Q+ + D + K +++ + + L+KLK L L+K+ DC D K
Sbjct: 521 NFAEEMKAKNTSQETMLRDLQE-KINQQENSLTLEKLK---LAVADLEKQ-RDCSQDLLK 575
Query: 543 SIRDVPTLLGAKLDKYH----SLNEELDFLVTSYEEIIE------C----ADQRLAISHS 588
L KL K +L L+ YEE+ E C ++ L S
Sbjct: 576 KREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMES 635
Query: 589 QIAHLEERNKHLEDLIRKPREKARK--PRSKSLENHPKSMTM 628
+ +L+ + HLE ++ + K+ + R ++LE +++++
Sbjct: 636 EKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSV 677
Score = 72.8 bits (177), Expect = 9e-13
Identities = 91/392 (23%), Positives = 161/392 (41%), Gaps = 59/392 (15%)
Query: 173 LQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQ-----MKITKQQVFIDVINKLKENVEE 227
LQ L ++ IQEL+ SN LE +KELQ + + K+++ +I+ K +EE
Sbjct: 913 LQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEM-SSIISLNKREIEE 971
Query: 228 LIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQER 287
L ++ T K + S N ++M +Q + ANY+ +E+
Sbjct: 972 LTQEN----------------------GTLKEINASLNQEKMNLIQKSESFANYIDEREK 1009
Query: 288 YMTEMQQKNKSVSQYL-----EMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKE 342
++E+ + K L E ++ + Q+ +LE L + K
Sbjct: 1010 SISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKN 1069
Query: 343 AQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQIN 402
EQ L+E F K +E L + + R + L+ ++ +Q +E T N N
Sbjct: 1070 ELEQ----LKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDN------QN 1119
Query: 403 EVKNENAKLKQQV-ARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSP 461
K+E LKQ++ EEQN + K ++ D L+E + K KT H + P
Sbjct: 1120 NSKSEAGGLKQEIMTLKEEQNKMQK----EVNDLLQE--NEQLMKVMKTKHECQNLESEP 1173
Query: 462 C-------EERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDI 514
E N + K L K SL + L+ + ++ + +ESEK +
Sbjct: 1174 IRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKEC 1233
Query: 515 MLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRD 546
+ +L+++ +T + + D S E ++D
Sbjct: 1234 LQHELQTIRGDLETSNLQ--DMQSQEISGLKD 1263
Score = 66.6 bits (161), Expect = 7e-11
Identities = 68/301 (22%), Positives = 137/301 (45%), Gaps = 31/301 (10%)
Query: 163 VQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVI---- 218
+Q L + LQ+ K+ + + + +L LE ++E + K+ + +
Sbjct: 415 IQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKE 474
Query: 219 NKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIK 278
N+L+ ++EE+ ++ + + + +LE L N ++ L +S+N E ++ + +
Sbjct: 475 NELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQE 534
Query: 279 ANYVCLQERYMTEMQQKNKSVSQYLEM------------DKTLSKKEEEVERLQQLKKEL 326
LQE+ QQ+N + L++ L K+E +E+L +
Sbjct: 535 TMLRDLQEKI---NQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKT 591
Query: 327 E---KATASALDLLKREKEAQEQE---FLSLQEEFQKLEKENLEERQKLKSRLEKLLTQV 380
E KA SAL+L K+E E ++E F + E +KL + E++ L+S++ L T +
Sbjct: 592 EKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCL 651
Query: 381 RNLQFMSE--NERTKNIKLQQQ--INEVKNENAKLKQQVARSEEQN--YVPKFETAQLKD 434
+ Q S NER + +++ ++ E++N + L + E Q Y+ + A+ D
Sbjct: 652 KTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSD 711
Query: 435 Q 435
Q
Sbjct: 712 Q 712
Score = 58.9 bits (141), Expect = 1e-08
Identities = 95/454 (20%), Positives = 193/454 (42%), Gaps = 47/454 (10%)
Query: 63 EMLKFTEKSLAKSIAKESALNPSQPPSFLCKTAVPSKEIQNYGEIPEMSVSYEK-EVTAE 121
E++K TE+SL I +E L S A K++ ++ E + + E
Sbjct: 2280 EIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVE 2339
Query: 122 GVERPEIVSTWSSAGISWRSEACRENCEM--PDWEQSAESLQPVQEDMA-LNEVLQKLKH 178
+ER ++ + + +E + E E +SL+ ++ D+ + + L +
Sbjct: 2340 NLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTN 2399
Query: 179 TNRKQEVRIQELQC-----SNLYLEKRVKELQMK---ITKQQVFIDVINKLKENVEELIE 230
+K++ RI EL+ N+ EK +++QMK T ++ + +L E V L
Sbjct: 2400 ELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHN 2459
Query: 231 DKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMT 290
D+ ++ + ++ LE A + L E++N NY+ LQ
Sbjct: 2460 DQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKN--------------NYIVLQSSVNG 2505
Query: 291 EMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLS 350
+Q+ + + D+ +S+ + +++ +QL +L + L K + +
Sbjct: 2506 LIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEH-QLWKEQNLELRNLTVE 2564
Query: 351 LQEEFQKLEKEN------LEERQKLKSRLEKLL--TQVRNLQFMSE-NERT-KNIKLQQQ 400
L+++ Q L+ +N LE Q LE L T++ + F+ + N+ T K +LQ++
Sbjct: 2565 LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQRE 2624
Query: 401 INEVKNENAKLKQQVARSEEQNYVPKF-----ETAQLKDQLEEVL--KSDITKDTKTTHS 453
++E+ + A+L+++++ E+ + E KDQL+E+ S++ K H
Sbjct: 2625 MHEMAQKTAELQEELS-GEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHK 2683
Query: 454 NLLPDCSPCEERLNPADIKRASQLASKMHSLLAL 487
+ + E + A+ + A K H L L
Sbjct: 2684 DQVEKEGKVREEI--AEYQLRLHEAEKKHQALLL 2715
Score = 58.5 bits (140), Expect = 2e-08
Identities = 100/487 (20%), Positives = 195/487 (40%), Gaps = 66/487 (13%)
Query: 182 KQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKND 241
+ E + +++ L+ ++ L+ + QQ+ N E V L D+ + +E +
Sbjct: 625 ENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYN---ERVRTLEMDRENLSVEIRN 681
Query: 242 TKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMT----EMQQKNK 297
L + + V TQK K Q + + +CL+ +T +++ K +
Sbjct: 682 LHNVLDS-KSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQ 740
Query: 298 SVS-QYLEMDKTLSKKEEEVERLQQLKKELEKATASALD-----LLKREKEAQEQEFLSL 351
+S + ++ D+ E E L+ L K + + + D L ++ A F ++
Sbjct: 741 LLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANI 800
Query: 352 QEEFQKLEKENLE---ERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNEN 408
E + E E E + L +V +L+F E+++ N LQ+Q E+
Sbjct: 801 IGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIK 860
Query: 409 AKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNP 468
++++ + ++E+ + ET+Q +L+E DT + H N++ +
Sbjct: 861 GEIEENLMKAEQMHQSFVAETSQRISKLQE--------DT-SAHQNVVAE---------- 901
Query: 469 ADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKT 528
S L +K L L D + ++ +E +K + ++ LK L L +T
Sbjct: 902 ----TLSALENKEKELQLL-------NDKVETEQAEIQELKKSNHLLEDSLKELQLLSET 950
Query: 529 LD---KEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQR--- 582
L KE+ S + I ++ G + SLN+E L+ E D+R
Sbjct: 951 LSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKS 1010
Query: 583 ---LAISHSQ-----IAHLEERNKHLEDLIRKPREKARKPRSKSLENHPKSMTMMPALFK 634
L+ + Q + EE EDL +K KA + ++ LE T +L +
Sbjct: 1011 ISELSDQYKQEKLILLQRCEETGNAYEDLSQK--YKAAQEKNSKLECLLNECT---SLCE 1065
Query: 635 ENRNDLD 641
+N+L+
Sbjct: 1066 NRKNELE 1072
Score = 57.4 bits (137), Expect = 4e-08
Identities = 108/490 (22%), Positives = 213/490 (43%), Gaps = 67/490 (13%)
Query: 144 CRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHT----NRKQEVRIQELQCSNLY--- 196
C + M EQS + P++E+ L ++KL+ +KQ +Q+L+ S +
Sbjct: 2276 CGDQEIMKATEQSLDP--PIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADL 2333
Query: 197 ----LEKRVKELQMKITKQQVFIDVINKLKENVEEL---IEDKYKIILEKNDTKKTLQNL 249
+E +EL++ T Q+ K VE L IE + + T+++
Sbjct: 2334 LKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSE 2393
Query: 250 EEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTL 309
+E L N + QE ++ E++ F+ I LQE+ ++Q K KS + + L
Sbjct: 2394 KENLTNELQKEQERISELEIINSSFENI------LQEKEQEKVQMKEKSSTAMEMLQTQL 2447
Query: 310 SKKEEEVERL---QQLKKELEKATASALDLLKREK-------EAQEQEFLSLQEEF---- 355
+ E V L Q+ K E+ +S ++ L+ EK + + ++ LQ
Sbjct: 2448 KELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLI 2507
Query: 356 -------QKLEKENLEERQKLKSRL---EKLLTQVRNLQ-----FMSENERTKN--IKLQ 398
QKLEK++ EE +LK+++ E+L++++ ++ + +N +N ++L+
Sbjct: 2508 QEVEDGKQKLEKKD-EEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELE 2566
Query: 399 QQINEVKNENAKLKQ--QVARSEEQNYVPKFETAQL-KDQLEEVLKSDITKDTKTTHS-- 453
Q+I ++++NA L+ +V +S +N + E ++ K E + K+T+
Sbjct: 2567 QKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMH 2626
Query: 454 NLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGL----LTCQDIINS-DAEHFKES 508
+ + +E L+ + A +L + + + L L ++ S D H +
Sbjct: 2627 EMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQV 2686
Query: 509 EK---VSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEEL 565
EK V + + + LH +K ++D + I+ L +K + S E+
Sbjct: 2687 EKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEI 2746
Query: 566 DFLVTSYEEI 575
D L +S EE+
Sbjct: 2747 DLLKSSKEEL 2756
Score = 55.5 bits (132), Expect = 2e-07
Identities = 78/369 (21%), Positives = 165/369 (44%), Gaps = 62/369 (16%)
Query: 142 EACRENCEMPDWEQSAESLQPVQEDMAL-NEVLQKLKHTNRKQEVRIQELQCSNLYLEKR 200
E R ++ D EQ L V+ + L E +L++ + E +IQ LQ N L+
Sbjct: 2523 EISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDT 2582
Query: 201 VKELQ---------MKITK--QQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNL 249
++ LQ +++TK + F++ +NK+ EL + +++ + + ++ L
Sbjct: 2583 LEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGE 2642
Query: 250 EEVLANT-QKHLQESRNDKEMLQ---LQFKKIKANYVCLQERYMTEMQQKNKSVSQY--- 302
+ LA Q L+E ++ K+ L+ L+ ++K + C+ + + + + + +++Y
Sbjct: 2643 KNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLR 2702
Query: 303 ------------LEMDKT-----------LSKKEE-------EVERLQQLKKELE---KA 329
L+ +K L+ KEE E++ L+ K+EL KA
Sbjct: 2703 LHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKA 2762
Query: 330 TASALDLLKREKEAQEQEFLSLQEEFQ------KLEKENLEERQKLKSRLEKLLTQVRNL 383
T L+ LK+ K + L++E + KL ++ ++ ++ K L+K L+Q++
Sbjct: 2763 TTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAA 2822
Query: 384 QFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSD 443
Q + + K+ + E+K L+++ ++E Y+ K+ L E++ K+
Sbjct: 2823 QEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADE--YLDKY--CSLLISHEKLEKAK 2878
Query: 444 ITKDTKTTH 452
+T+ H
Sbjct: 2879 EMLETQVAH 2887
Score = 53.5 bits (127), Expect = 6e-07
Identities = 94/462 (20%), Positives = 189/462 (40%), Gaps = 59/462 (12%)
Query: 171 EVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIE 230
E + +L+ K VRI+ + L++ +++KE + + + D + L+ ++ E
Sbjct: 2112 EEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLK---DKVENLERELQMSEE 2168
Query: 231 DKYKIILEKNDTKKTLQNLE---EVLANTQK----HLQESRNDKEMLQLQF--------- 274
++ +IL+ ++K ++ L+ E +A + K L R++KE L Q
Sbjct: 2169 NQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSE 2228
Query: 275 --KKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATAS 332
K + + L+E+ E+Q K +S + + L + E V L +E+ KAT
Sbjct: 2229 LDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCG-DQEIMKATEQ 2287
Query: 333 ALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERT 392
+LD E+ L+ + EK+ L Q+LK E ++ R
Sbjct: 2288 SLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKES-EHHADLLKG--------RV 2338
Query: 393 KNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFE--TAQLKDQLEEVLKSDITKDTKT 450
+N++ + +I E+A L+ + ++ E + K E T L+ L+ D+ ++
Sbjct: 2339 ENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRG-----LELDVV-TIRS 2392
Query: 451 THSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEK 510
NL + +ER++ +I + S ++L Q+ + ++S
Sbjct: 2393 EKENLTNELQKEQERISELEI-----INSSFENIL---------QEKEQEKVQMKEKSST 2438
Query: 511 VSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEE------ 564
+++ +LK L+ + L + C + E V L K L+E
Sbjct: 2439 AMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIV 2498
Query: 565 LDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRK 606
L V + +E Q+L +I+ L+ + + E L+ K
Sbjct: 2499 LQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSK 2540
Score = 51.2 bits (121), Expect = 3e-06
Identities = 86/470 (18%), Positives = 202/470 (42%), Gaps = 36/470 (7%)
Query: 155 QSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVK-------ELQMK 207
Q + + ++ + L +++ +LK N +++ C + L +RV+ +L+M
Sbjct: 1814 QEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMH 1873
Query: 208 ITK--QQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRN 265
K ++ D + K+ ++ +E D + E + + ++E + L+ +
Sbjct: 1874 ADKSSREDIGDNVAKVNDSWKERFLD---VENELSRIRSEKASIEHEALYLEADLEVVQT 1930
Query: 266 DKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKE 325
+K L+ + + VCL+E ++N+ + M K + ++ E++++ +E
Sbjct: 1931 EKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQE 1990
Query: 326 LEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQF 385
LE + L + + EA+ +E L + E L+++ L+ +L+ L + L
Sbjct: 1991 LESHQSECLHCI-QVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSL 2049
Query: 386 MSENERTKNIKLQQQINEVKNENAKLKQQVARSE-EQNYVPKFETAQLKDQLEEVLKSDI 444
+ +L ++ + E+ L+ +++ S+ E+ V K A L ++ E L+
Sbjct: 2050 TKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSS 2109
Query: 445 TKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEH 504
T++ L R+ AD K+ +A K+ L +D + +
Sbjct: 2110 TQEEV---HQLRRGIEKLRVRIE-ADEKKQLHIAEKLKERERENDSL---KDKVENLERE 2162
Query: 505 FKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIR----DVPTLLGAKLDKYHS 560
+ SE+ ++++ ++ + +TL ++ + A+S++ D+ TL K +
Sbjct: 2163 LQMSEENQELVILDAENSKAEVETLKTQI----EEMARSLKVFELDLVTLRSEKENLTKQ 2218
Query: 561 LNE------ELDFLVTSYEEIIECADQ-RLAISHSQIAHLEERNKHLEDL 603
+ E ELD L++S++ ++E +Q + I +E L++L
Sbjct: 2219 IQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKEL 2268
Score = 50.4 bits (119), Expect = 5e-06
Identities = 94/456 (20%), Positives = 188/456 (41%), Gaps = 81/456 (17%)
Query: 195 LYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIIL-EKNDTKKTLQNLEE-- 251
LYLE ++ +Q +++ ++ N+ K+ V +E++ ++ E+N + L + +
Sbjct: 1919 LYLEADLEVVQT----EKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKT 1974
Query: 252 -VLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKS-VSQYLEMD--K 307
L + ++E + E Q + CL + E + K K+ + Q L D +
Sbjct: 1975 TALDQLSEKMKEKTQELESHQSE---------CLHCIQVAEAEVKEKTELLQTLSSDVSE 2025
Query: 308 TLSKKEEEVERLQQLKKELEKATASALDL------LKREKEAQEQEFLSLQEEFQKLEKE 361
L K E+LQ L+K+ + + + +L L +EKE +E SLQ + + E
Sbjct: 2026 LLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYE 2085
Query: 362 NLEERQKLKSRL-----------------EKLLTQVRNLQFMSENERTKNIKLQQQINEV 404
L + L++ L +L + L+ E + K + + +++ E
Sbjct: 2086 KLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKER 2145
Query: 405 KNENAKLKQQVARSEEQNYV--------------PKFETAQLKDQLEEVLKS--DITKDT 448
+ EN LK +V E + + K E LK Q+EE+ +S D
Sbjct: 2146 ERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDL 2205
Query: 449 KTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKES 508
T S +E L ++ QL S++ LL+ LL ++ ++ + +ES
Sbjct: 2206 VTLRSE--------KENLTKQIQEKQGQL-SELDKLLSSFKSLL--EEKEQAEIQIKEES 2254
Query: 509 EKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFL 568
+ +++ +LK L+ E + + + ++ L +++ H L ++ L
Sbjct: 2255 KTAVEMLQNQLKELN--------EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKL 2306
Query: 569 ---VTSYEEIIECADQRLAISHSQIAHLEERNKHLE 601
+ + E+ C Q+L S L+ R ++LE
Sbjct: 2307 RARLEADEKKQLCVLQQLKESEHHADLLKGRVENLE 2342
Score = 45.4 bits (106), Expect = 2e-04
Identities = 58/248 (23%), Positives = 109/248 (43%), Gaps = 24/248 (9%)
Query: 149 EMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKI 208
EM D + +++S E L + + LK K + + +L N E+ +K ++ K
Sbjct: 1113 EMTDNQNNSKS-----EAGGLKQEIMTLKEEQNKMQKEVNDLLQEN---EQLMKVMKTKH 1164
Query: 209 TKQQVFIDVI-NKLKENVEELIEDKYKIILEKNDTKKTLQN-------LEEVLANTQKHL 260
Q + + I N +KE E + +K ++ + +L + LE +L N + L
Sbjct: 1165 ECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKL 1224
Query: 261 QESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMD--KTLSKKEEEVER 318
QES +KE LQ + + I+ + L+ + +MQ + S + E+D + E+
Sbjct: 1225 QESEKEKECLQHELQTIRGD---LETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELST 1281
Query: 319 LQQLKKELE---KATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEK 375
Q L+ + T + L+ L++ E + E L E E + +K+ + K
Sbjct: 1282 SQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMAEEVGK 1341
Query: 376 LLTQVRNL 383
LL +V+ L
Sbjct: 1342 LLNEVKIL 1349
Score = 45.4 bits (106), Expect = 2e-04
Identities = 105/542 (19%), Positives = 226/542 (41%), Gaps = 79/542 (14%)
Query: 149 EMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVK------ 202
E P+ EQ SL P+ E + + L ++++ ++ ELQ L L+ K
Sbjct: 1371 EQPN-EQHPVSLAPLDESNSY----EHLTLSDKEVQMHFAELQEKFLSLQSEHKILHDQH 1425
Query: 203 -ELQMKITKQQVFID-------VINKLKENVEELIEDKYKIILEKN----------DTKK 244
++ K+++ Q ++D V++ N + + + ++ LE+
Sbjct: 1426 CQMSSKMSELQTYVDSLKAENLVLSTNLRNFQGDLVKEMQLGLEEGLVPSLSSSCVPDSS 1485
Query: 245 TLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKN-------- 296
+L +L + ++ + L E D +L + AN + E + + +Q++N
Sbjct: 1486 SLSSLGD--SSFYRALLEQTGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPS 1543
Query: 297 ---KSVSQYLEM----DKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFL 349
K V + + ++L K EE++E +K + + L ++E + +++L
Sbjct: 1544 APAKGVEELESLCEVYRQSLEKLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYL 1603
Query: 350 SLQEEF-QKLEKENLEERQKL---KSRLEKLLTQVR----NLQFMSENERTKNIKLQQQI 401
S E++ QKL LE KL K + E+L ++ LQ + + R+ +
Sbjct: 1604 SENEQWQQKLTSVTLEMESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLLGIDTEDA 1663
Query: 402 NEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQ-LEEVLKSDITKDTKTTHSNLLPDCS 460
+ +NE+ + ++ SE PK + Q+ D+ ++ L DI K T+T +CS
Sbjct: 1664 IQGRNESCDISKE-HTSETTERTPKHDVHQICDKDAQQDLNLDIEKITETGAVKPTGECS 1722
Query: 461 ----------PCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEK 510
P E + S+L+ + L M L +DI N KE+
Sbjct: 1723 GEQSPDTNYEPPGEDKTQGSSECISELSFSGPNALVPMDFLGNQEDIHNLQL-RVKETSN 1781
Query: 511 VSDIMLQKLKSLHLKKKTLDKEVIDCDS----------DEAKSIRDVPTLLGAKLDKYHS 560
+ +L ++ K ++L E+ + DS + ++ ++ ++G +
Sbjct: 1782 ENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSD 1841
Query: 561 LNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKH-LEDLIRKPREKARKPRSKSL 619
L+E+L++ ++E+++ + ++ H ++ ++ + D + K + + K R +
Sbjct: 1842 LSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVND-SWKERFLDV 1900
Query: 620 EN 621
EN
Sbjct: 1901 EN 1902
Score = 33.9 bits (76), Expect = 0.47
Identities = 27/116 (23%), Positives = 59/116 (50%), Gaps = 18/116 (15%)
Query: 316 VERLQQLKKELEKATASALDLLKREKEAQEQEF----LSLQEEFQKLEKENLE------E 365
++++Q+L+ +L+K LK+EK+ ++ + +LQ++ QK+E E E E
Sbjct: 17 LQKIQELEGQLDK--------LKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRE 68
Query: 366 RQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQ 421
Q+L E L + + + + ++ + Q+N K + KL+Q++ R + +
Sbjct: 69 NQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSE 124
Score = 31.6 bits (70), Expect = 2.4
Identities = 19/71 (26%), Positives = 37/71 (52%)
Query: 350 SLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENA 409
+L+E + L L++ Q+L+ +L+KL + + QF ++ K +Q++ K E
Sbjct: 4 ALEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGT 63
Query: 410 KLKQQVARSEE 420
LK++ R E
Sbjct: 64 NLKRENQRLME 74
Score = 31.2 bits (69), Expect = 3.1
Identities = 24/115 (20%), Positives = 51/115 (44%), Gaps = 4/115 (3%)
Query: 246 LQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEM 305
+Q LE L +K Q+ + + L+ +K K E TE + + +E+
Sbjct: 20 IQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKV----ENEKTEGTNLKRENQRLMEI 75
Query: 306 DKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEK 360
++L K ++++ Q+K+ L+ K++ E EQE + E ++ ++
Sbjct: 76 CESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQ 130
Score = 30.0 bits (66), Expect = 6.8
Identities = 31/135 (22%), Positives = 63/135 (46%), Gaps = 25/135 (18%)
Query: 244 KTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYL 303
+ LQ ++E+ + L + + +K+ Q Q ++A QK K +
Sbjct: 15 RALQKIQEL----EGQLDKLKKEKQQRQFQLDSLEAAL------------QKQKQKVENE 58
Query: 304 EMDKTLSKKEEEVERLQQLKKELEKAT---ASALDLLKREKEAQEQEFLSLQEEFQKLEK 360
+ + T K+E + RL ++ + LEK + L + + + QE + S +++ +KLE
Sbjct: 59 KTEGTNLKRENQ--RLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLE- 115
Query: 361 ENLEERQKLKSRLEK 375
+E ++ KS LE+
Sbjct: 116 ---QELKRCKSELER 127
Score = 29.6 bits (65), Expect = 8.9
Identities = 25/101 (24%), Positives = 52/101 (51%), Gaps = 11/101 (10%)
Query: 346 QEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQ---QQIN 402
Q+ L+ + KL+KE +Q+ + +L+ L ++ + ENE+T+ L+ Q++
Sbjct: 18 QKIQELEGQLDKLKKE----KQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLM 73
Query: 403 EVKNENAKLKQQVARS-EEQNYVPKFETAQL---KDQLEEV 439
E+ K KQ+++ + + F+ QL K Q+E++
Sbjct: 74 EICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKL 114
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 79.7 bits (195), Expect = 8e-15
Identities = 114/526 (21%), Positives = 227/526 (43%), Gaps = 81/526 (15%)
Query: 164 QEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYL--EKRVKELQMKI------------- 208
+E A +E L K+K K E ++E++ + L EK + Q++
Sbjct: 852 EELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRA 911
Query: 209 ---TKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRN 265
K+Q ++++ L+ VEE E + EK + +Q+LEE L + Q+ +
Sbjct: 912 RLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQL 971
Query: 266 DKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKE 325
+K + + KK++ + L+++ +++K + E L+++EE+ + L +++ +
Sbjct: 972 EKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNK 1031
Query: 326 LEKATASALDLLKREKEAQEQ-----------------EFLSLQEEFQKLEKENLEERQK 368
E + + LK+E++ +++ + LQ + +L+ + ++ ++
Sbjct: 1032 QEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEE 1091
Query: 369 LKSRL-----------------EKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKL 411
L+ L +L Q+ LQ E+E+ K ++Q ++ E L
Sbjct: 1092 LQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEAL 1151
Query: 412 KQQV-------ARSEEQNYVPKFETAQLKDQLEEVLKSDIT--KDTKTTHSNLLPDCSPC 462
K ++ A +E + E A+LK LEE K+ +D + H+ L + S
Sbjct: 1152 KTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQ 1211
Query: 463 EERLN--PADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLK 520
E+ A++++ Q + LA V +L + +++EH K D +Q+L
Sbjct: 1212 LEQAKRFKANLEKNKQGLETDNKELACEVKVL---QQVKAESEH---KRKKLDAQVQELH 1265
Query: 521 SLHLKKKTLDKEVIDCDSDEAKSIRDVPTLL------GAKLDK-YHSLNEELDFLVTSYE 573
+ + L E+ + S + +V TLL G K K SL +L + E
Sbjct: 1266 AKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQ---DTQE 1322
Query: 574 EIIECADQRLAISHSQIAHLEERNKHLEDLIRKPREKARKPRSKSL 619
+ E Q+L +S S+I LEE L++ ++ E+ARK K +
Sbjct: 1323 LLQEETRQKLNLS-SRIRQLEEEKNSLQEQ-QEEEEEARKNLEKQV 1366
Score = 72.4 bits (176), Expect = 1e-12
Identities = 100/493 (20%), Positives = 212/493 (43%), Gaps = 53/493 (10%)
Query: 154 EQSAESLQPVQEDMALN-EVLQKLK----HTNRKQEVRIQELQCSNLYLEKRVKELQMKI 208
E++ + L+ +++A +VLQ++K H +K + ++QEL ++ EL K
Sbjct: 1223 EKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKA 1282
Query: 209 TKQQVFIDVINKLKENVEELIEDKYKIILEKNDTK--KTLQNLEEVLANTQKHLQESRND 266
+K Q +D NV L+E+ EK K K +LE L +TQ+ LQE
Sbjct: 1283 SKLQNELD-------NVSTLLEEA-----EKKGIKFAKDAASLESQLQDTQELLQEETRQ 1330
Query: 267 KEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKEL 326
K L + ++++ LQE+ E + + Q L + L+ +++V+ + L
Sbjct: 1331 KLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESL 1390
Query: 327 EKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFM 386
E+A L ++ EA Q + KLEK + +L+ L+ L + + + +
Sbjct: 1391 EEAKKKLL----KDAEALSQRLEEKALAYDKLEK----TKNRLQQELDDLTVDLDHQRQV 1442
Query: 387 SENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVL--KSDI 444
+ N K K Q + E K+ +A+ ++ R+E + + + L LEE L K +
Sbjct: 1443 ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEF 1502
Query: 445 TKDTKTTHSNLLPDCSPCEERLNPADI--KRASQLASKMHSLLALMVGLLTCQDIINSDA 502
+ K +++ E+ ++ D K +L +L + + T + + +
Sbjct: 1503 ERQNKQLRADM-------EDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDEL 1555
Query: 503 EHFKESEKVSDIMLQKLKSL------------HLKKKTLDKEV--IDCDSDEAKSIRDVP 548
+ ++++ ++ +Q +K+ KK+ L K+V ++ + ++ + R +
Sbjct: 1556 QATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALA 1615
Query: 549 TLLGAKLD-KYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKP 607
K++ L +++ + +E+I+ + A LEE +++ +
Sbjct: 1616 VASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQS 1675
Query: 608 REKARKPRSKSLE 620
+E +K +S E
Sbjct: 1676 KESEKKLKSLEAE 1688
Score = 60.5 bits (145), Expect = 5e-09
Identities = 65/321 (20%), Positives = 146/321 (45%), Gaps = 31/321 (9%)
Query: 149 EMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYL-------EKRV 201
++ D E E+ ++++ + L+KL+ + + ++E + S + EK++
Sbjct: 1625 DLKDLEAQIEAANKARDEVI--KQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKL 1682
Query: 202 KELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTL----QNLEEVLANTQ 257
K L+ +I + Q + + + + E+ ++ I K L + LE +A +
Sbjct: 1683 KSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLE 1742
Query: 258 KHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVE 317
+ L+E +++ E+L +F+K L E KS + ++++ + + +++
Sbjct: 1743 EELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQ 1802
Query: 318 RLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLL 377
L+ K KAT SAL E + L+E+ ++ KE KL R EK L
Sbjct: 1803 ELEGAVKSKFKATISAL----------EAKIGQLEEQLEQEAKER-AAANKLVRRTEKKL 1851
Query: 378 TQVRNLQFMS-ENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQL 436
++ FM E+ER + ++Q+ + +LK+Q+ +EE+ +L+ +L
Sbjct: 1852 KEI----FMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1907
Query: 437 EEVLKSD--ITKDTKTTHSNL 455
++ +++ ++++ T + L
Sbjct: 1908 DDATEANEGLSREVSTLKNRL 1928
Score = 56.6 bits (135), Expect = 7e-08
Identities = 81/423 (19%), Positives = 176/423 (41%), Gaps = 42/423 (9%)
Query: 158 ESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVK---------ELQMKI 208
E L ++D+ N + +L+ + R E +++E++ LE ++ E+ M+
Sbjct: 1514 EDLMSSKDDVGKN--VHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 209 TKQQVFIDVINKLKENVEE---LIEDKYKIILEKNDTKK-------TLQNLEEVLANTQK 258
K Q D+ + ++N E+ LI+ ++ E D +K + + +E L + +
Sbjct: 1572 MKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEA 1631
Query: 259 HLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVER 318
++ + ++ + Q +K++A Q +++ +Q E +K L E E+ +
Sbjct: 1632 QIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQ 1691
Query: 319 LQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLT 378
LQ+ E+A +R E + E + L+E+++L++R+ +L
Sbjct: 1692 LQEELASSERA--------RRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEE 1743
Query: 379 QVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEE 438
++ Q E + K Q++ + E A + +S+ + + +LK +L+E
Sbjct: 1744 ELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQE 1803
Query: 439 VLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDII 498
L+ + K T S L EE+L +RA+ + L + +D
Sbjct: 1804 -LEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVED-E 1861
Query: 499 NSDAEHFKESEKVSDIMLQKLK-----------SLHLKKKTLDKEVIDCDSDEAKSIRDV 547
A+ +KE + ++ +++LK + ++ L +E+ D R+V
Sbjct: 1862 RRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREV 1921
Query: 548 PTL 550
TL
Sbjct: 1922 STL 1924
Score = 47.8 bits (112), Expect = 3e-05
Identities = 78/383 (20%), Positives = 169/383 (44%), Gaps = 34/383 (8%)
Query: 244 KTLQNLEEVLANTQKHLQESRNDKEMLQLQFK--KIKANYVCLQERYMTEMQQKNKSVSQ 301
+ ++ +L T++ + D+E+L+++ K K++ ++ ++ +++KN Q
Sbjct: 836 RVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQ 895
Query: 302 YLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQ---EQEFLSLQEEFQKL 358
+ ++ EE RL K+ELE+ ++ E+E + E +Q Q L
Sbjct: 896 LQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDL 955
Query: 359 EKE-NLEERQKLKSRLEKLLTQVRNLQFMSEN---ERTKNIKLQQQINEVKNENAKLKQQ 414
E++ + EE + K +LEK+ + + ++ M E +N K ++ +++ A+ Q
Sbjct: 956 EEQLDEEEGARQKLQLEKVTAEAK-IKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQ 1014
Query: 415 VARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRA 474
+A EE+ A+++++ +EV+ SD+ + K + + +L+
Sbjct: 1015 LAEEEEK----AKNLAKIRNK-QEVMISDLEERLK-KEEKTRQELEKAKRKLDGETTDLQ 1068
Query: 475 SQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVI 534
Q+A + L + L ++ + + + L+ ++ L + L +
Sbjct: 1069 DQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE--- 1125
Query: 535 DCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIE--CADQRLAISHSQ-IA 591
D +S++A + A+ K L+EEL+ L T E+ ++ A Q L Q +A
Sbjct: 1126 DFESEKASRNK-------AEKQK-RDLSEELEALKTELEDTLDTTAAQQELRTKREQEVA 1177
Query: 592 H----LEERNKHLEDLIRKPREK 610
LEE K+ E I+ R++
Sbjct: 1178 ELKKALEEETKNHEAQIQDMRQR 1200
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 79.3 bits (194), Expect = 1e-14
Identities = 113/517 (21%), Positives = 227/517 (43%), Gaps = 57/517 (11%)
Query: 155 QSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVF 214
Q E LQ + LN + +K T + EL L LE + +EL I++++
Sbjct: 436 QEKEELQ--MSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETL 493
Query: 215 IDVINKL----KENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDK--- 267
I I +L +E + +I K ++ ++N+ + L++ L + +K + + +DK
Sbjct: 494 IAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDI 553
Query: 268 -EMLQLQFKKIKANYVCLQERYMTEM----------------QQKNKSVS-QYLEMDKTL 309
+ L +Q +K+ + V L + ++T+ Q+ N S+ + LE+ + +
Sbjct: 554 TKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHI 613
Query: 310 SKKEEEVERLQ-QLKKELEKATASAL-DLLKREKEAQEQEFLSLQEEFQKLEKENLEERQ 367
+ EEE+ R++ +L + L + + S D L +E+EA+ + E ++L + +
Sbjct: 614 RQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAF 673
Query: 368 KLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKF 427
+K EKL+ +++ E N +L + N + LK + E + K
Sbjct: 674 DVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVE---TLKMEKGEIEAELCWAK- 729
Query: 428 ETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCE-ERLNPADIKRASQLASKMHSLLA 486
K LEE K + T + + NL E E L + K+ ++A ++
Sbjct: 730 -----KRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQ 784
Query: 487 LMVGLLTCQDIINSDAEHFKESEKV---SDIMLQKLKSLHLK-KKTLDK--EVIDCDSDE 540
+ +D+++S E K+ ++ +I ++KLK K ++ LDK + + +
Sbjct: 785 MDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEIL 844
Query: 541 AKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIA--------- 591
++I + LG+ ++ + L EEL+ L AD + S +++A
Sbjct: 845 RQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTI 904
Query: 592 --HLEERNKHLEDLIRKPREKARKPRSKSLENHPKSM 626
HLEE KH + +I + + +++ +SL+ K M
Sbjct: 905 KEHLEEEIKHHQKII-EDQNQSKMQLLQSLQEQKKEM 940
Score = 68.6 bits (166), Expect = 2e-11
Identities = 73/304 (24%), Positives = 142/304 (46%), Gaps = 50/304 (16%)
Query: 163 VQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVIN--K 220
+QE L + ++K++ ++ +Q +Q + L++ + +LQ QV +D N K
Sbjct: 1208 LQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQA-----QVLVDSDNNSK 1262
Query: 221 LKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEML---------Q 271
L+ + LI+ E+N+TK L+N + LA Q + + N K++L Q
Sbjct: 1263 LQVDYTGLIQS-----YEQNETK--LKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQ 1315
Query: 272 LQFKKIKA--NYVCLQERYMTEMQQKNKSVSQYLE-MDKTLSKKEEEVERLQQLKKELEK 328
L + + CL+ + + ++ + Q LE + K+L +K+ + LQ+ L
Sbjct: 1316 LSSASLLTPQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSD 1375
Query: 329 ATASALDLLKREKEAQEQEFLSLQEE---FQKLEKENLEERQKLKSRLEKLLTQVRNLQF 385
+ A+ +L ++E E + E L+E+ QKL KE + LL + ++ Q
Sbjct: 1376 SIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKE------------KDLLIKAKSDQL 1423
Query: 386 MSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDIT 445
+S NE N NEN L+Q V +E+ + + + +LK + E+++++
Sbjct: 1424 LSSNENFTN---------KVNENELLRQAVTNLKERILILEMDIGKLKGENEKIVETYRG 1474
Query: 446 KDTK 449
K+T+
Sbjct: 1475 KETE 1478
Score = 67.0 bits (162), Expect = 5e-11
Identities = 111/464 (23%), Positives = 205/464 (44%), Gaps = 55/464 (11%)
Query: 155 QSAESLQPVQEDMA------LNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRV---KELQ 205
QSAE L+ + ++ L + L++L+ + ++++ I+ LQ +N L + EL+
Sbjct: 1325 QSAECLRASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELE 1384
Query: 206 MK--------ITKQQVFIDVINKLKENVEELIEDKYKIILEKND--TKKTLQN--LEEVL 253
K I + + DV+ KL + + LI+ K +L N+ T K +N L + +
Sbjct: 1385 RKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAV 1444
Query: 254 ANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYL-EMDKTLSKK 312
N ++ + D L+ + +KI Y + Y +Q+ N S L E +
Sbjct: 1445 TNLKERILILEMDIGKLKGENEKIVETYRGKETEYQA-LQETNMKFSMMLREKEFECHSM 1503
Query: 313 EEEVERLQQLKKELEKATASALD-LLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKS 371
+E+ +QL KE E+ L+ LL K QE+ + QE Q + L+++Q +
Sbjct: 1504 KEKALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLA--LKQKQMENT 1561
Query: 372 RLEKLLTQVRNLQFMS--ENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFET 429
L+ + ++R+ +F S E ER +N L+ +E++ ++ +A + + + K T
Sbjct: 1562 ALQNEVQRLRDKEFRSNQELERLRNHLLE-------SEDSYTREALAAEDREAKLRKKVT 1614
Query: 430 AQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKR---ASQLASKMHSLLA 486
LEE L S +H + +E+LN +R A QL+ +
Sbjct: 1615 V-----LEEKLVSSSNAMENASHQASV-QVESLQEQLNVVSKQRDETALQLSVSQEQVKQ 1668
Query: 487 LMVGLLTCQDIINSDAEHFKESEKV---SDIMLQKLKSLHLKK--KTLDKEVIDCDS--D 539
+ L Q ++ EHF++ EK +++ QK KK + L+ +VI D
Sbjct: 1669 YALSLANLQMVL----EHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLD 1724
Query: 540 EAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRL 583
EA + D + L +LD EEL +E+++ ++L
Sbjct: 1725 EANAALDSASRLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKL 1768
Score = 65.9 bits (159), Expect = 1e-10
Identities = 105/506 (20%), Positives = 224/506 (44%), Gaps = 68/506 (13%)
Query: 140 RSEACRENCEMPDWEQS-AESLQPVQEDMAL--NEVLQKLKHTNRKQEVRIQELQCSNLY 196
+SE C+ + + +Q+ ++ + Q +M++ N QKL +R+ + +
Sbjct: 208 QSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDY------ 261
Query: 197 LEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANT 256
E+R++EL+ + QQ VI + E+ + + +EK ++ K ++ LE+ + +
Sbjct: 262 -EERIEELENLL--QQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDI 318
Query: 257 QKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKE--- 313
K L + ND+++L+ + +++ + E + +K ++ T+++KE
Sbjct: 319 NKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERIL 378
Query: 314 ------EEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENL-EER 366
EEV RLQQ + E L + A++ L ++ E + EK L +E+
Sbjct: 379 AQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEK 438
Query: 367 QKLKSRLEKL--------LTQVRNLQFMSE-NERTKNIKL-QQQINEVKNENAKLKQQVA 416
++L+ L KL T R++ SE ++ N++ +Q++N+ +E L ++
Sbjct: 439 EELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIE 498
Query: 417 RSEEQNYVPKFETAQLKDQLEE----------VLKSDITKDTKTTHSNLLPDCSPCEERL 466
+ QN +KDQL + LK D+ + K H L D + L
Sbjct: 499 ELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVH-QLEDDKMDITKEL 557
Query: 467 NPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKK 526
D+++ + S++ +L L + +D + + + +S++ S++ +QK ++L LK+
Sbjct: 558 ---DVQKEKLIQSEV-ALNDLHLTKQKLEDKVENLVDQLNKSQE-SNVSIQK-ENLELKE 611
Query: 527 KTLDKE----------VIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEI- 575
E + + D + +D TLL + + +L + L L E +
Sbjct: 612 HIRQNEEELSRIRNELMQSLNQDSNSNFKD--TLLKEREAEVRNLKQNLSELEQLNENLK 669
Query: 576 -----IECADQRLAISHSQIAH-LEE 595
++ +++L ++ + H LEE
Sbjct: 670 KVAFDVKMENEKLVLACEDVRHQLEE 695
Score = 58.2 bits (139), Expect = 2e-08
Identities = 71/357 (19%), Positives = 157/357 (43%), Gaps = 62/357 (17%)
Query: 112 VSYEKEVTAEGV--ERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDMAL 169
+S EK E + E+ EI A + W + E E +E++ E L + L
Sbjct: 703 LSLEKNTIVETLKMEKGEI-----EAELCWAKKRLLE--EANKYEKTIEELSNARN---L 752
Query: 170 NEVLQKLKHT-----NRKQEVRIQELQCSNLYLE--------------KRVKELQMKITK 210
N +L+H N+K+++ I EL+ + ++ + K+L I K
Sbjct: 753 NTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINK 812
Query: 211 QQVFIDVINKLKENVEELIE--DKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKE 268
+++FI+ KLKE +L E DKY L KN+ L + + + L + +
Sbjct: 813 KEIFIE---KLKERSSKLQEELDKYSQALRKNEI------LRQTIEEKDRSLGSMKEENN 863
Query: 269 MLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEK 328
LQ + ++++ E Q + V+ +D ++++ EV +L +K+ LE+
Sbjct: 864 HLQEELERLR------------EEQSRTAPVADPKTLD-SVTELASEVSQLNTIKEHLEE 910
Query: 329 ATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSE 388
+++ + +++ Q SLQE+ +++++ + Q + + L + ++ + +
Sbjct: 911 EIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQK 970
Query: 389 NERTKNIKLQQQINEVKNENAKLKQQ-------VARSEEQNYVPKFETAQLKDQLEE 438
+L ++ +++ +N+ + Q+ + E++ + K ET +L ++E
Sbjct: 971 TIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKE 1027
Score = 53.5 bits (127), Expect = 6e-07
Identities = 88/467 (18%), Positives = 196/467 (41%), Gaps = 69/467 (14%)
Query: 158 ESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMK---------- 207
E L + + NE+L++ T +++ + ++ N +L++ ++ L+ +
Sbjct: 829 EELDKYSQALRKNEILRQ---TIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADP 885
Query: 208 -----ITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQE 262
+T+ + +N +KE++EE I+ KII ++N +K L + LQE
Sbjct: 886 KTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQL----------LQSLQE 935
Query: 263 SRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKT-LSKKEEEVE---- 317
+ + + + Q +++ A + L E ++ KS+ + +E KT L ++ ++++
Sbjct: 936 QKKEMDEFRYQHEQMNATHTQL----FLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNS 991
Query: 318 ------RLQQL-------KKELEKATASALDLLKREKEAQ----EQEFLSLQEEFQKLEK 360
++Q L K +L KA L +E+E + ++ +SL ++ +L K
Sbjct: 992 DIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSK 1051
Query: 361 ENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEE 420
+ + + ++ + + L Q + + S + + LQQQ+ E K+ +
Sbjct: 1052 DEVGKLTQIIQQ-KDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTR 1110
Query: 421 QNYVPKFETAQLKD----------QLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPAD 470
+N K E ++ D +L++ K T+ + + D
Sbjct: 1111 ENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIREKD 1170
Query: 471 IKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLD 530
I+ L+ K +LLA++ T + ++ F+E + D + Q++K + K+ +
Sbjct: 1171 IE-IDALSQKCQTLLAVLQTSSTGNEAGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVM 1229
Query: 531 KEVIDCDSDEAKSIRDVPTLLGAKL---DKYHSLNEELDFLVTSYEE 574
V + + A+ ++ L L D L + L+ SYE+
Sbjct: 1230 TTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLIQSYEQ 1276
Score = 51.2 bits (121), Expect = 3e-06
Identities = 100/505 (19%), Positives = 210/505 (41%), Gaps = 66/505 (13%)
Query: 155 QSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKI------ 208
+ + +Q D+ +Q L N ++ + + + L + +EL++K+
Sbjct: 981 EERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNI 1040
Query: 209 --TKQ--QVFIDVINKLKENVEEL---IEDKYKIILEKNDTKKTLQNLEEVLANTQKH-- 259
TKQ Q+ D + KL + +++ I+ + I + T+ + +++ A +
Sbjct: 1041 SLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREK 1100
Query: 260 ----LQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEE 315
L E + L+ ++ K+ + V +E + ++Q +NK +S E E
Sbjct: 1101 VFAVLNEKTRENSHLKTEYHKMM-DIVAAKEAALIKLQDENKKLSTRFESSGQ-DMFRET 1158
Query: 316 VERLQQLKKE-------LEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQK 368
++ L ++ +E L + + L +L+ E ++ +F++L L+ER K
Sbjct: 1159 IQNLSRIIREKDIEIDALSQKCQTLLAVLQTSSTGNEAGGVN-SNQFEEL----LQERDK 1213
Query: 369 LKSRLEKL-------LTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQ---VARS 418
LK +++K+ +T V+N+Q S + + +LQ Q+ + N+KL+ + +S
Sbjct: 1214 LKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLIQS 1273
Query: 419 EEQN--YVPKF--ETAQLKDQLEEVL--------KSDITKDTKTTHSNLLPDCSPCEERL 466
EQN + F E AQ++ + ++ K DI ++ S L P + C
Sbjct: 1274 YEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASLLTPQSAECLRAS 1333
Query: 467 NPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKK 526
+ +S+L + L L L I + E+ + ++SD + + +
Sbjct: 1334 KSEVLSESSELLQQ--ELEELRKSLQEKDATIRTLQEN---NHRLSDSIAATSELERKEH 1388
Query: 527 KTLDKEVIDCDSDE---AKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYE---EIIECAD 580
+ D E+ + K +++ L+ AK D+ S NE V E + +
Sbjct: 1389 EQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLK 1448
Query: 581 QRLAISHSQIAHLEERNKHLEDLIR 605
+R+ I I L+ N+ + + R
Sbjct: 1449 ERILILEMDIGKLKGENEKIVETYR 1473
Score = 41.6 bits (96), Expect = 0.002
Identities = 65/314 (20%), Positives = 129/314 (41%), Gaps = 40/314 (12%)
Query: 297 KSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQ 356
+ ++Q + T + + E+ +LQ + KEL++ + +D + E + E
Sbjct: 192 RHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEIS 251
Query: 357 KLEKENLEERQKLKSRLEKLLTQ----------------VRNLQFMSENERTKNIKLQQQ 400
+ +E L + ++ LE LL Q + +Q + + K++Q
Sbjct: 252 RRHREELSDYEERIEELENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQL 311
Query: 401 INEVKNENAKL------KQQVARSEEQNYVPK----FETAQLKDQLEEVLKSDITK-DTK 449
+++K+ N KL + + R +EQ V K E LK + ++ S + + DT
Sbjct: 312 EDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTM 371
Query: 450 TTHSNLLPDCSPCEE--RLNPA------DIKRASQLASKMHSLLALMVGLLTCQDIINSD 501
T +L + EE RL A +I R S L ++ +SL + L +++ +
Sbjct: 372 TEKERILAQSASVEEVFRLQQALSDAENEIMRLSSL-NQDNSLAEDNLKLKMRIEVLEKE 430
Query: 502 AEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSL 561
+ ++ + L KL + + K+ I DS+ + D+ L AK + +
Sbjct: 431 KSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSE----LHDLRLNLEAKEQELNQS 486
Query: 562 NEELDFLVTSYEEI 575
E + L+ EE+
Sbjct: 487 ISEKETLIAEIEEL 500
Score = 31.6 bits (70), Expect = 2.4
Identities = 55/296 (18%), Positives = 118/296 (39%), Gaps = 35/296 (11%)
Query: 266 DKEMLQLQFKKIKANYVCLQ------ERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERL 319
+ E+ + K+I+A + L+ ++ T++++K+++ ++ T + + L
Sbjct: 46 EAELPDSRTKEIEAIHAILRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQ-----L 100
Query: 320 QQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQ 379
QQ KE+E + LK + A + + L LQ Q + S ++
Sbjct: 101 QQ--KEVE------ISHLKARQIALQDQLLKLQSAAQSVPSGAGVPATTASSSFAYGISH 152
Query: 380 VRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEV 439
+ + + I QQ+IN + NE ++L+ +V K + DQ E
Sbjct: 153 HPSAFHDDDMDFGDIISSQQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEIC 212
Query: 440 LKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLA-------SKMHSLLALMVGLL 492
+I K+ K S + D L A ++ ++++ S + + LL
Sbjct: 213 KLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLL 272
Query: 493 T--CQDIINSDAEHFKESEKVSDIM-------LQKLKSLHLKKKTLDKEVIDCDSD 539
+I +D E +K ++ +K++ L K K ++K++ ++D
Sbjct: 273 QQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAEND 328
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 78.2 bits (191), Expect = 2e-14
Identities = 58/294 (19%), Positives = 150/294 (51%), Gaps = 13/294 (4%)
Query: 156 SAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFI 215
SA+ V+E+ N + Q+ + +QE +IQE + E++++E + KI +Q+ +
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 216 DVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFK 275
++ EE + + +++ EK + + L+ + + L+E +++E ++ Q +
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE 397
Query: 276 KIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALD 335
K + +E + E +++ + ++ ++ + ++EE++ R Q+ K ++ +
Sbjct: 398 KRQ------EEEKIREQEKRQEQEAKMWRQEEKIREQEEKI-REQEKKMWRQEEKIHEQE 450
Query: 336 LLKREKEAQEQEFLSLQEEFQK------LEKENLEERQKLKSRLEKLLTQVRNLQFMSEN 389
++ E++ QEQE + QEE + +KE + E++K++ + EK+ Q + E
Sbjct: 451 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK 510
Query: 390 ERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSD 443
R + K+ +Q +++ + K+++Q + EQ + + + ++ +Q E++ + +
Sbjct: 511 IREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
Score = 70.1 bits (170), Expect = 6e-12
Identities = 61/314 (19%), Positives = 161/314 (51%), Gaps = 16/314 (5%)
Query: 140 RSEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEK 199
+ E R EM WE+ + + + E +++L+ ++E +I+EL+ ++ ++
Sbjct: 333 QEEKMRRQEEMM-WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE-EKMHEQE 390
Query: 200 RVKELQMK------ITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVL 253
+++E + K I +Q+ + K+ E++ E + KI + KK + E++
Sbjct: 391 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI---REQEKKMWRQEEKIH 447
Query: 254 ANTQKHLQESRNDKEMLQLQFKKIKANY-VCLQERYMTEMQQKNKSVSQYLEMDKTLSKK 312
+ +E R ++E + Q +KI+ + Q+ M E ++ K + ++ + +
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
Query: 313 EEEV-ERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKL--EKENLEERQKL 369
EE++ E+ +++ ++ EK + ++E++ +EQE + +QE+ +K+ ++E ++E++K+
Sbjct: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM-MQEQEEKMGEQEEKMQEQEKM 566
Query: 370 KSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFET 429
+ + EK+ Q ++ E R + K+ +Q +++ + +++Q + EQ +
Sbjct: 567 RRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 626
Query: 430 AQLKDQLEEVLKSD 443
++++Q E++ + +
Sbjct: 627 EKMQEQEEKMRRQE 640
Score = 67.8 bits (164), Expect = 3e-11
Identities = 86/468 (18%), Positives = 211/468 (45%), Gaps = 73/468 (15%)
Query: 174 QKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEEL----- 228
++LK N K + ++Q ++ ++ VKEL+ K+ + ++ + +L+ + L
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ-QQLQAEADHLGKELQ 275
Query: 229 -IEDKYKIILEKNDTKKTL-QNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQE 286
+ K + +E+N+ L Q EE + ++ +QE +E +Q Q +KI+ QE
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW---EEKIQEQEEKIRE-----QE 327
Query: 287 RYMTEMQQKNKSVSQYL--------EMDKTLSKKEEEVERLQQLK-------KELEKATA 331
+ E ++K + + + ++ + +KEE++ RL+++ +ELE+
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
Query: 332 SALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNL----QFMS 387
+ ++E++ QE+E + QE+ Q+ E + + +K++ + EK+ Q + + + +
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 388 ENERTKNIKLQQQINEVKNENAKLKQQ--VARSEEQNYVPKFETAQLKDQLEEVLKSDIT 445
E E+ + + +Q+ E+ + K+++Q + R +E+ + E +++ Q E+V + +
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMH----EQEKIRKQEEKVWRQE-- 501
Query: 446 KDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHF 505
+ H EE++ + K Q ++ I E
Sbjct: 502 ---EKMHDQ--------EEKIREQEEKMWRQEEKIREQ-----------EEKIREQEEKI 539
Query: 506 KESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEEL 565
+E E++ +K+ K + +K + + IR+ + + +K E++
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKM-----RRQEEKIREQEEKIREQKEKIREQEEKI 594
Query: 566 ---DFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKPREK 610
+ + EE+++ ++++ ++ EE+ + E+ +R+ EK
Sbjct: 595 WEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Score = 66.6 bits (161), Expect = 7e-11
Identities = 60/293 (20%), Positives = 141/293 (48%), Gaps = 29/293 (9%)
Query: 139 WRSEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEV-----RIQELQCS 193
W E E WE+ E ++ ++E M E +++ + +++E + QE +
Sbjct: 359 WEKEEKMRRLEEMMWEKE-EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417
Query: 194 NLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILE-KNDTKKTLQNLEEV 252
E++++E + KI +Q+ K EE I ++ KI E K ++ + EE
Sbjct: 418 MWRQEEKIREQEEKIREQE-------KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 470
Query: 253 LANTQK--HLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLS 310
+ ++ +E +++E ++ Q +K V QE M + ++K + E ++ +
Sbjct: 471 IREQEEIWRQKEKMHEQEKIRKQEEK-----VWRQEEKMHDQEEKIR------EQEEKMW 519
Query: 311 KKEEEVERLQQLKKELEKATASALDLL--KREKEAQEQEFLSLQEEFQKLEKENLEERQK 368
++EE++ ++ +E E+ +++ + EK +++E + QE+ ++ E++ E+ +K
Sbjct: 520 RQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK 579
Query: 369 LKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQ 421
++ + EK+ Q + E R + +Q+Q ++ + K+ +Q + +EQ
Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632
Score = 63.9 bits (154), Expect = 4e-10
Identities = 101/528 (19%), Positives = 223/528 (42%), Gaps = 61/528 (11%)
Query: 148 CEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMK 207
C P+ EQ A Q AL L+ HT R + ELQ + Y + VK+L+ +
Sbjct: 104 CHSPEDEQKASH----QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGE 159
Query: 208 ITK---------------QQVFIDVINKLKEN---VEELIEDKYKIILEKNDTKKTLQNL 249
+Q V + K+ +EEL +++ + LE T + L
Sbjct: 160 ARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEEL 219
Query: 250 EEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYL--EMDK 307
+E A Q+ LQ ++K +QL K++K L+ + QQ+ ++ + +L E+
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRK---LERAKLLLPQQQLQAEADHLGKELQS 276
Query: 308 TLSKKEEEVE------RLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKE 361
+K + +VE RL Q ++E + + + + QE++ +E+ ++ E++
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 362 NLEERQKLKSRLEKLLTQ----------VRNLQFMSENERTKNIKLQQQIN--------- 402
+ + + + EK+ Q +R L+ M + K +L+++++
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQE 396
Query: 403 EVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPC 462
E + E K+++Q R E++ + + E ++++Q E++ + + + +
Sbjct: 397 EKRQEEEKIREQEKRQEQEAKMWRQE-EKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 455
Query: 463 EERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSD----IMLQK 518
E+R ++ R + + + + + I + + +++ EK+ D I Q+
Sbjct: 456 EKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQE 515
Query: 519 LKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEEL--DFLVTSYEEII 576
K ++K ++E + ++ + IR+ ++ + +K E++ + EE I
Sbjct: 516 EKMWRQEEKIREQE--EKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Query: 577 ECADQRLAISHSQIAHLEERNKHLEDLIRKPREKARKPRSKSLENHPK 624
++++ +I EE+ E+ IR+ E ++ K E K
Sbjct: 574 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
Score = 50.4 bits (119), Expect = 5e-06
Identities = 47/234 (20%), Positives = 110/234 (47%), Gaps = 19/234 (8%)
Query: 114 YEKEVTAEGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDMALNEVL 173
+E+E E +R E W + E RE E+ W Q E + ++ E +
Sbjct: 447 HEQEKIREEEKRQEQEEMWR------QEEKIREQEEI--WRQK-EKMHEQEKIRKQEEKV 497
Query: 174 QKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKY 233
+ + QE +I+E + E++++E + KI +Q+ I ++ + EE + ++
Sbjct: 498 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE 557
Query: 234 KIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQ 293
+ + E+ ++ + + E ++ ++ R +E + Q +KI+ QE M E +
Sbjct: 558 EKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE-----QEEMMQEQE 612
Query: 294 QKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQE 347
+K + + +K ++E+ E+ ++++++ EK + L ++E++ QE +
Sbjct: 613 EK-----MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Score = 45.8 bits (107), Expect = 1e-04
Identities = 38/179 (21%), Positives = 90/179 (50%), Gaps = 11/179 (6%)
Query: 153 WEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQ 212
W Q + ++ E + + + R+QE +I+E + E+ ++E + K+ +Q+
Sbjct: 498 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE 557
Query: 213 VFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQL 272
+ K++ E++ E + KI + K+ ++ EE + ++ ++E +EM+Q
Sbjct: 558 EKMQEQEKMRRQEEKIREQEEKI----REQKEKIREQEEKIWEQEEKIRE---QEEMMQE 610
Query: 273 QFKKI--KANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKA 329
Q +K+ + +C QE M E ++K + + + + +++E E++Q+ ++ LE A
Sbjct: 611 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE--EKMQEHQEHLEAA 667
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 77.4 bits (189), Expect = 4e-14
Identities = 98/558 (17%), Positives = 241/558 (43%), Gaps = 59/558 (10%)
Query: 99 KEIQNYGEIPEMSVSYEKEVTAEGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAE 158
+ N P M++ ++ + + E + ++T + E R + E+
Sbjct: 823 RSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMV 882
Query: 159 SLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMK----------- 207
SL + D+ L +Q E R + L S + LE +VKEL +
Sbjct: 883 SLLQEKNDLQLQ--VQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSEL 940
Query: 208 ITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDK 267
+ K++ D + LK ++++L K+ EK+ T+ ++NL E + ++++ + +K
Sbjct: 941 VAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEK 1000
Query: 268 EMLQ---------LQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVER 318
+ LQ LQ ++ K N + + +++Q+ + LE +K L E +R
Sbjct: 1001 KSLQEAHQQTLDDLQVEEDKVNGLI---KINAKLEQQTDDLEGSLEQEKKLRADLERAKR 1057
Query: 319 LQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEER---QKLKSRLEK 375
+L+ +L+ + S +D L+ +K+ E++ + E +L+ + +E+ + + ++++
Sbjct: 1058 --KLEGDLKMSQESIMD-LENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKE 1114
Query: 376 LLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSE-------EQNYVPKFE 428
L ++ L+ E E T K+++Q +++ E ++ +++ + E N + E
Sbjct: 1115 LQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAE 1174
Query: 429 TAQLKDQLEE-VLKSDIT--------KDTKTTHSNLLPDCSPCEERLNPADIKRASQLAS 479
+++ LEE L+ + T D+ + + +++L + ++
Sbjct: 1175 FQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1234
Query: 480 KMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSD 539
++ AL + + + F E + + Q + L+++K L + + +
Sbjct: 1235 MASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQ----NGE 1290
Query: 540 EAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKH 599
+ + + +L+ +L ++L+ L EE + + + +AH + ++H
Sbjct: 1291 LSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETK--------AKNAMAHALQSSRH 1342
Query: 600 LEDLIRKPREKARKPRSK 617
DL+R+ E+ ++ +++
Sbjct: 1343 DCDLLREQYEEEQEAKAE 1360
Score = 65.9 bits (159), Expect = 1e-10
Identities = 104/490 (21%), Positives = 215/490 (43%), Gaps = 58/490 (11%)
Query: 154 EQSAESLQPVQEDMALNEV-LQKLKHT------NRKQEVRIQELQCSNLYLEKR------ 200
E SL+ +D+ L ++K KH N +E+ E S L EK+
Sbjct: 948 EDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAH 1007
Query: 201 ---VKELQMKITKQQVFIDVINKLKENVEEL---IEDKYKIILEKNDTKKTLQNLEEVLA 254
+ +LQ++ K I + KL++ ++L +E + K+ + D ++ + LE L
Sbjct: 1008 QQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKL---RADLERAKRKLEGDLK 1064
Query: 255 NTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEE 314
+Q+ + + NDK+ ++ + KK + LQ + E + + E+ + + EE
Sbjct: 1065 MSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEE 1124
Query: 315 EVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLE 374
E+E L+ ++EK + L+ E E+ + + + + K+ E QK++ LE
Sbjct: 1125 EIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIE-MNKKREAEFQKMRRDLE 1183
Query: 375 KLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKD 434
+ Q +E T ++Q + V A+L +Q+ + + E ++LK
Sbjct: 1184 EATLQ---------HEATAATLRKKQADSV----AELGEQIDNLQRVKQKLEKEKSELKM 1230
Query: 435 QLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTC 494
++++ + S+I +K + SN+ C E++ ++IK + +++ L + L
Sbjct: 1231 EIDD-MASNIEALSK-SKSNIERTCRTVEDQF--SEIKAKDEQQTQLIHDLNMQKARLQT 1286
Query: 495 QDIINSDAEH-FKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGA 553
Q N + H +E E + + + ++L + + L +++ +E K+ A
Sbjct: 1287 Q---NGELSHRVEEKESLISQLTKSKQALTQQLEELKRQM----EEETKA-------KNA 1332
Query: 554 KLDKYHSLNEELDFLVTSYEEIIEC-ADQRLAISHSQIAHLEERNKHLEDLIRKPR--EK 610
S + D L YEE E A+ + A+S + + R K+ D I++ E+
Sbjct: 1333 MAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEE 1392
Query: 611 ARKPRSKSLE 620
A+K ++ L+
Sbjct: 1393 AKKKLAQRLQ 1402
Score = 63.2 bits (152), Expect = 7e-10
Identities = 66/327 (20%), Positives = 154/327 (47%), Gaps = 37/327 (11%)
Query: 154 EQSAESLQPV--QEDMALNEVLQ---KLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKI 208
+++AE+LQ V E + N+ L+ K++ + E+++ +K ++ +Q ++
Sbjct: 1595 QRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQL 1654
Query: 209 TKQQVFIDVINKLKENVEE---LIEDKYKIILEK-NDTKKTLQNLEEVLANTQKHLQESR 264
Q+ +D + E+++E ++E + ++LE+ + K L+ E +++ L ++
Sbjct: 1655 KDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDAS 1714
Query: 265 NDKEMLQLQF-------KKIKANYVCLQERYMTEMQQKN-------KSVSQYLEMDKTLS 310
+ ++L Q KK++A+ Q +Q+ K+++ M + L
Sbjct: 1715 DRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELK 1774
Query: 311 KKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLE------KENLE 364
K+++ L+++KK LE+ DL R EA++ +++ QKLE + L+
Sbjct: 1775 KEQDTSAHLERMKKNLEQTVK---DLQHRLDEAEQLALKGGKKQIQKLENRVRELENELD 1831
Query: 365 ERQKLKSRL----EKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEE 420
QK + K +V+ + + +E + ++LQ +++++ + K+Q +EE
Sbjct: 1832 VEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEE 1891
Query: 421 QNYVPKFETAQLKDQLEEVL-KSDITK 446
Q +++ +LEE ++DI +
Sbjct: 1892 QANTQLSRCRRVQHELEEAAERADIAE 1918
Score = 59.3 bits (142), Expect = 1e-08
Identities = 100/516 (19%), Positives = 212/516 (41%), Gaps = 74/516 (14%)
Query: 149 EMPDWEQSAESLQPVQEDM-----ALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKE 203
E+ D + E+L + ++ + + ++K + +Q I +L L+ + E
Sbjct: 1231 EIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGE 1290
Query: 204 LQMKITKQQVFIDVINKLKENVEELIEDKYKIILE----KNDTKKTLQNLEEVLANTQKH 259
L ++ +++ I + K K+ + + +E+ + + E KN LQ+ ++
Sbjct: 1291 LSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQ 1350
Query: 260 LQESRNDKEMLQLQFKKIKANYVCLQERYMT-------EMQQKNKSVSQYLE-------- 304
+E + K LQ K + + +Y T E+++ K ++Q L+
Sbjct: 1351 YEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTET 1410
Query: 305 -------MDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQK 357
++KT + + EVE L ++LE++ + L K+++ + L E QK
Sbjct: 1411 ANSKCASLEKTKQRLQGEVE---DLMRDLERSHTACATLDKKQRNFDKV----LAEWKQK 1463
Query: 358 LEKENLE------ERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKL 411
L++ E E + L + L K+ + E R +N LQ++I+++ + A+
Sbjct: 1464 LDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAET 1523
Query: 412 KQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADI 471
+ + +E+ + + E + L+ LEEV S +++K L + S + L+ I
Sbjct: 1524 GKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQL--ELSQVKSELDRKVI 1581
Query: 472 KR---ASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKK-- 526
++ QL + +L + +DA K+ + D+ +++ H +
Sbjct: 1582 EKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKME-GDLNEMEIQLGHSNRQM 1640
Query: 527 -------KTLDKEVIDCD---SDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYE--- 573
+T+ ++ D D +S D+ L + L EEL+ + + E
Sbjct: 1641 AETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTE 1700
Query: 574 --------EIIECADQRLAISHSQIAHLEERNKHLE 601
E+++ +D R+ + HSQ L K LE
Sbjct: 1701 RTRRLSEQELLDASD-RVQLLHSQNTSLINTKKKLE 1735
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 75.9 bits (185), Expect = 1e-13
Identities = 103/471 (21%), Positives = 219/471 (46%), Gaps = 52/471 (11%)
Query: 158 ESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDV 217
+S + +E + E ++K T K E R +EL+ + L + +LQ+++ +Q D
Sbjct: 843 KSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQ---DN 899
Query: 218 INKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLA-------NTQKHLQESRNDKEML 270
+N +E ++LI++K ++ + + + L++ EE+ A + E + D + L
Sbjct: 900 LNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDL 959
Query: 271 QLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKAT 330
+L K++ +E++ TE + KN + + ++ +E + +L + KK L++A
Sbjct: 960 ELTLAKVE------KEKHATENKVKN--------LTEEMAGLDEIIAKLTKEKKALQEAH 1005
Query: 331 ASALDLLKREKEAQEQEFLSLQEEFQKLEKE------NLEERQKLKSRLEKLLTQVR-NL 383
ALD + + +E + SL + KLE++ +LE+ +K++ LE+ ++ +L
Sbjct: 1006 QQALD----DLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL 1061
Query: 384 QFMSEN-ERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLK------DQL 436
+ E+ +N KLQ + ++K + + QQ ++ E++ + +LK ++L
Sbjct: 1062 KLTQESIMDLENDKLQLE-EKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEEL 1120
Query: 437 EEVLKSDITKDTKT--THSNLLPDCSPCEERLNPADIKRASQLA--SKMHSLLALM---V 489
EE L+++ T K S+L + ERL A + Q+ K + M +
Sbjct: 1121 EEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 1180
Query: 490 GLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPT 549
T Q + A K ++ V+++ +++ +L K+ L+KE + + ++
Sbjct: 1181 EEATLQHEATAAALRKKHADSVAELG-EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQ 1239
Query: 550 LLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHL 600
++ AK + ++ L+ Y +E A + L +Q A L+ N L
Sbjct: 1240 IIKAKAN-LEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGEL 1289
Score = 72.4 bits (176), Expect = 1e-12
Identities = 104/511 (20%), Positives = 242/511 (47%), Gaps = 52/511 (10%)
Query: 140 RSEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEK 199
+SEA R+ + E+ SL + D+ L +Q + E R +L + + LE
Sbjct: 867 KSEARRK-----ELEEKMVSLLQEKNDLQLQ--VQAEQDNLNDAEERCDQLIKNKIQLEA 919
Query: 200 RVKELQMKI-----------TKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQN 248
+VKE+ ++ K++ D ++LK+++++L K+ EK+ T+ ++N
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 979
Query: 249 LEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKT 308
L E +A + + + +K+ LQ ++ + +++ + + K K Q +++ +
Sbjct: 980 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGS 1039
Query: 309 LSKKEEEVERLQQLKKELE---KATASAL-----DLLKREKEAQEQEFLSLQEEFQKLEK 360
L ++++ L++ K++LE K T ++ D L+ E++ +++EF + ++ K+E
Sbjct: 1040 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEF-DINQQNSKIED 1098
Query: 361 ENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSE- 419
E + Q L+ +L++ ++ L+ E ERT K+++ +++ E ++ +++ +
Sbjct: 1099 EQVLALQ-LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGG 1157
Query: 420 ------EQNYVPKFETAQLKDQLEE-VLKSDITKDT-KTTHSNLLPDCSPCEERLNPADI 471
E N + E +++ LEE L+ + T + H++ + + E+++ ++
Sbjct: 1158 ATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG---EQID--NL 1212
Query: 472 KRASQLASKMHSLLALMVGLLT--CQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTL 529
+R Q K S L + +T + II + A EKVS + + +K +
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA----NLEKVSRTLEDQANEYRVKLEEA 1268
Query: 530 DKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRL---AIS 586
+ + D + AK ++ L +L++ +L +L SY + +E ++L +
Sbjct: 1269 QRSLNDFTTQRAK-LQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKA 1327
Query: 587 HSQIAHLEERNKHLEDLIRKPREKARKPRSK 617
+ +AH + +H DL+R+ E+ + +++
Sbjct: 1328 KNALAHALQSARHDCDLLREQYEEETEAKAE 1358
Score = 65.5 bits (158), Expect = 1e-10
Identities = 105/472 (22%), Positives = 205/472 (43%), Gaps = 60/472 (12%)
Query: 21 KQDSFKEENPMETSVSANTDQLGNEYFRQPPPRSPPLIHCSGEMLKFTEKSLAKSIAK-- 78
KQ + ++ +E+S L E F+ L H E K K+L + I+
Sbjct: 1459 KQKYEESQSELESS-QKEARSLSTELFKLKNAYEESLEHL--ETFKRENKNLQEEISDLT 1515
Query: 79 ----ESALNPSQPPSFLCKTAVPSKEIQNYGEIPEMSVSYEKEVTAEG-VERPEIVSTWS 133
E N + + V E+Q+ E E S+ +E EG + R ++
Sbjct: 1516 EQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHE-----EGKILRAQLEFNQI 1570
Query: 134 SAGISWRSEACRENCEMP--DWEQSAESLQPV--QEDMALNEVLQ---KLKHTNRKQEVR 186
A I + E E + ++ +SLQ E + NEVL+ K++ + E++
Sbjct: 1571 KAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQ 1630
Query: 187 IQELQCSNLYLEKRVKELQMKITKQQVFID----VINKLKENVEELIEDKYKII---LEK 239
+ +K+VK LQ + Q+ +D + LKEN+ ++E + ++ LE+
Sbjct: 1631 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIA-IVERRNNLLQAELEE 1689
Query: 240 -----NDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQ 294
T+++ + E+ L T + +Q + L Q KK++++ LQ +Q+
Sbjct: 1690 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQE 1749
Query: 295 -------KNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQE 347
K+++ M + L K+++ L+++KK +E+ DL R EA++
Sbjct: 1750 CRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLDEAEQIA 1806
Query: 348 FLSLQEEFQKLEKE------NLEERQKLKSR----LEKLLTQVRNLQFMSENERTKNIKL 397
+++ QKLE LE QK + + K +++ L + +E ++ ++L
Sbjct: 1807 LKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRL 1866
Query: 398 QQQINEVKNENAKLKQQVARSEEQ--NYVPKFETAQLK-DQLEEVLKSDITK 446
Q +++++ + K+Q +EEQ + KF Q + D+ EE ++DI +
Sbjct: 1867 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEE--RADIAE 1916
Score = 57.4 bits (137), Expect = 4e-08
Identities = 137/758 (18%), Positives = 291/758 (38%), Gaps = 159/758 (20%)
Query: 10 QVYNYAKDNNIKQDSFKEENPMETSVSANTDQLGNEYFRQPPPRSPPLIHCSGE---MLK 66
Q+ K+N + + +EE E + A ++L ++ R+ S L G ++
Sbjct: 1105 QLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1164
Query: 67 FTEKSLAKSIAKESALNPSQPPSFLCKTAVPSKEIQNYGEIPEMSVSYEKEVTAEGVERP 126
+K A+ L + A+ K + E+ E + ++ E+
Sbjct: 1165 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1224
Query: 127 EIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVR 186
E E+ D + E + ++ L +V + L+ + V+
Sbjct: 1225 EF------------------KLELDDVTSNMEQI--IKAKANLEKVSRTLEDQANEYRVK 1264
Query: 187 IQELQCS-NLYLEKRVK------ELQMKITKQQVFIDVINKLKENVEELIEDKYKIILE- 238
++E Q S N + +R K EL ++ +++ I + + K + + +ED + + E
Sbjct: 1265 LEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEE 1324
Query: 239 ---KNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMT----- 290
KN LQ+ ++ +E K LQ K + + +Y T
Sbjct: 1325 GKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1384
Query: 291 --EMQQKNKSVSQYLE---------------MDKTLSKKEEEVERLQQLKKELEKATASA 333
E+++ K ++Q L+ ++KT + + E+E L + E A A+A
Sbjct: 1385 TEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLM-VDVERSNAAAAA 1443
Query: 334 LDLLKR------------------EKEAQEQEFLSLQEEFQKLEK--------------- 360
LD +R E E+ ++E SL E KL+
Sbjct: 1444 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRE 1503
Query: 361 -------------------ENLEERQKLKSRLE----KLLTQVRNLQFMSENERTKNIKL 397
+N+ E +K++ +LE +L + + + E+E K ++
Sbjct: 1504 NKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRA 1563
Query: 398 QQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLP 457
Q + N++K A++++++A +E+ K ++ D L+ L ++ + + +L
Sbjct: 1564 QLEFNQIK---AEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAE-----TRSRNEVLR 1615
Query: 458 DCSPCEERLNPADIK--RASQLASKMHSLLALMVGLLTCQDIINSDA----EHFKES--- 508
E LN +I+ A+++A++ + + LL I DA + KE+
Sbjct: 1616 VKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAI 1675
Query: 509 -EKVSDIMLQKLKSLHL-------KKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHS 560
E+ ++++ +L+ L +K ++E+I+ S+ + + T L +++
Sbjct: 1676 VERRNNLLQAELEELRAVVEQTERSRKLAEQELIE-TSERVQLLHSQNTSL---INQKKK 1731
Query: 561 LNEELDFLVTSYEEII-ECAD----------------QRLAISHSQIAHLEERNKHLEDL 603
+ +L L + EE + EC + + L AHLE K++E
Sbjct: 1732 MESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT 1791
Query: 604 IRKPREKARKPRSKSLENHPKSMTMMPALFKENRNDLD 641
I+ + + + +L+ K + + A +E +L+
Sbjct: 1792 IKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELE 1829
Score = 49.3 bits (116), Expect = 1e-05
Identities = 88/410 (21%), Positives = 172/410 (41%), Gaps = 45/410 (10%)
Query: 232 KYKIILEKNDTKKTLQNLEEVLANTQKHLQESR--------------NDKEMLQLQFKKI 277
K K +L+ +T+K + ++E ++ L++S +K LQLQ +
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 896
Query: 278 KANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLL 337
+ N +ER ++ K + ++ EM++ L +EE L K++LE + L
Sbjct: 897 QDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSE----L 952
Query: 338 KREKEAQEQEFLSLQEEFQKLE---KENLEERQKLKSRLEKLLTQVRNLQFMSENERTKN 394
K++ + E +++E E K EE L + KL + + LQ +
Sbjct: 953 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 1012
Query: 395 IKLQQQINEVKNENAKLKQQVARSE---EQNYVPKFETAQLKDQLEEVLKSDITKDTKTT 451
+ ++N + KL+QQV E EQ + + + K +LE LK T+ +
Sbjct: 1013 QVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL-----TQES 1067
Query: 452 HSNLLPDCSPCEERLNPADI---KRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKES 508
+L D EE+L + ++ S++ + L L L Q I + E E+
Sbjct: 1068 IMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARI-EELEEELEA 1126
Query: 509 EKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLD-KYHSLNEELDF 567
E+ + ++KL+S + + E I +EA V + K + ++ + +L+
Sbjct: 1127 ERTARAKVEKLRS----DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1182
Query: 568 LVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKPREKARKPRSK 617
+E ++ A S +A L E+ D +++ ++K K +S+
Sbjct: 1183 ATLQHEATAAALRKKHADS---VAELGEQ----IDNLQRVKQKLEKEKSE 1225
Score = 48.5 bits (114), Expect = 2e-05
Identities = 74/370 (20%), Positives = 158/370 (42%), Gaps = 15/370 (4%)
Query: 254 ANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKE 313
A T+K + + + ++ +K +A L+E+ ++ +Q+KN Q L+ E
Sbjct: 845 AETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAE 904
Query: 314 EEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRL 373
E ++L + K +LE + L+ E+E + L + +KLE E E ++ + L
Sbjct: 905 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKKDIDD-L 959
Query: 374 EKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLK 433
E L +V + +EN + KN L +++ + AKL ++ +E + + +
Sbjct: 960 ELTLAKVEKEKHATEN-KVKN--LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEE 1016
Query: 434 DQLEEVLKSDITKDTKTTH-SNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLL 492
D++ + KS + + + L L A K L S++ L L
Sbjct: 1017 DKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKL 1076
Query: 493 TCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLG 552
++ + + F +++ S I +++ +L L+KK + + +E + +
Sbjct: 1077 QLEEKLKK--KEFDINQQNSKIEDEQVLALQLQKKLKENQ---ARIEELEEELEAERTAR 1131
Query: 553 AKLDKYHS-LNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKPREKA 611
AK++K S L+ EL+ + EE ++ ++ + A ++ + LE+ + A
Sbjct: 1132 AKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATA 1191
Query: 612 RKPRSKSLEN 621
R K ++
Sbjct: 1192 AALRKKHADS 1201
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 75.5 bits (184), Expect = 1e-13
Identities = 56/268 (20%), Positives = 134/268 (50%), Gaps = 8/268 (2%)
Query: 156 SAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFI 215
SA+ V+E+ N + Q+ + +QE +IQE + E +++E + K+ +Q+
Sbjct: 275 SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE--- 331
Query: 216 DVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFK 275
K+ E E++ E + K+ ++ ++ + + E + ++ R E +Q Q +
Sbjct: 332 ---EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
Query: 276 KIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALD 335
++ ++E+ ++ + + E D+ + ++EEE+ R ++ +ELE+ +
Sbjct: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
Query: 336 LLKREKEAQEQEFLSLQEEFQKLEK--ENLEERQKLKSRLEKLLTQVRNLQFMSENERTK 393
L+ +E ++E +QE+ +K+++ E ++E+++ R EKLL Q + E +
Sbjct: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ 508
Query: 394 NIKLQQQINEVKNENAKLKQQVARSEEQ 421
K+ +Q +++ + K+++Q + EQ
Sbjct: 509 EEKMWEQEEKMQEQEEKMQRQEEKMREQ 536
Score = 66.6 bits (161), Expect = 7e-11
Identities = 59/275 (21%), Positives = 139/275 (50%), Gaps = 32/275 (11%)
Query: 153 WEQSAESLQPVQEDMALNEV--------LQKLKHTNRKQEVRIQELQCSNLYLEKRVKEL 204
W Q E +Q +E M E+ + + + +QE +I+E + E++++E
Sbjct: 300 WRQE-EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358
Query: 205 QMKITKQQVFI-DVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQES 263
+ KI +Q+ + K++E E++ E + ++ ++ ++ + +E + +K ++E
Sbjct: 359 EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQ 418
Query: 264 ----RNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYL-EMDKTLSKKEEEVER 318
R +E + Q +KI+ E M + ++K + V + + E ++ + ++EE+++R
Sbjct: 419 DEKIREQEEEMWRQEEKIRE-----LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
Query: 319 LQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLT 378
++ +E E+ T LLK+E++ EQE E+ + E++ E+ +K++ + EK
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEK--- 525
Query: 379 QVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQ 413
+Q E R + ++L QQ +++ + +L++
Sbjct: 526 ----MQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Score = 56.2 bits (134), Expect = 9e-08
Identities = 89/503 (17%), Positives = 207/503 (41%), Gaps = 75/503 (14%)
Query: 149 EMPDWEQSAESLQPVQ---------EDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEK 199
E D +Q ESL+ V ED ++ V + + R +++ N K
Sbjct: 92 ESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRK 151
Query: 200 RV---------------KELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKK 244
RV K + + ++ + D ++ +E+L +++ LE
Sbjct: 152 RVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTI 211
Query: 245 TLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLE 304
T + L+E A Q+ L+ ++K +QL K +K ER + Q Q L+
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL----ERAQLLLPQ------QQLQ 261
Query: 305 MDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLE 364
++ KE LQ + +L+ A +L + QE++ +E+ Q+ E++ E
Sbjct: 262 VEADRLGKE-----LQSVSAKLQ-AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCE 315
Query: 365 ERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYV 424
+ K++ + EK+ Q + E R + K+ +Q +++ + K+++Q + Q
Sbjct: 316 QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 425 PKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSL 484
+ + ++++Q EE+ + EE++ + KR ++ + +
Sbjct: 376 IREQDEKIQEQEEEMWRQ--------------------EEKIREQEEKRQEKMWRQEKKM 415
Query: 485 LALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSI 544
+ I + E +++ EK+ ++L+ + ++ +EV + +E + +
Sbjct: 416 RE------QDEKIREQEEEMWRQEEKI-----RELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 545 RDVPTLLGAKLDKYHSLNEEL---DFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLE 601
++ + + +K E+ + L+ E+I E ++++ ++ EE+ + E
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE-QEEKMWRQEEKMWEQEEKMQEQE 523
Query: 602 DLIRKPREKARKPRSKSLENHPK 624
+ +++ EK R+ + + K
Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEK 546
Score = 48.5 bits (114), Expect = 2e-05
Identities = 50/212 (23%), Positives = 106/212 (50%), Gaps = 12/212 (5%)
Query: 164 QEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFI-DVINKLK 222
+++ E + + + R+Q+ +I+E + E++++EL+ + Q+ + +V K++
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 223 ENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRN---DKEMLQLQFKKIKA 279
E E++ E + KI ++ + K +Q EE +K L++ +E + Q +K+
Sbjct: 459 EEEEKMQEQEEKI--QRQEEK--IQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE 514
Query: 280 NYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEK--ATASALDLL 337
+QE+ +Q+ K Q + + + K +E+ RLQ+L++ L K A L
Sbjct: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGA 574
Query: 338 KREKEAQEQEFLS--LQEEFQKLEKENLEERQ 367
RE +Q L+ LQ E + E ++L+++Q
Sbjct: 575 GRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606
Score = 31.6 bits (70), Expect = 2.4
Identities = 37/139 (26%), Positives = 68/139 (48%), Gaps = 17/139 (12%)
Query: 139 WRSEA-CRENCEMPDWEQSAESLQPVQEDMALNEV-LQKLKHTNRKQEVRIQELQCSNLY 196
WR E RE EM + E L+ V+E M E +Q+ + ++QE +IQE +
Sbjct: 430 WRQEEKIRELEEM--MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR 487
Query: 197 LEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANT 256
EK +K+ + KI +Q+ K+ E++ E + K+ + ++ +Q EE +
Sbjct: 488 QEKLLKQ-EEKIWEQE------EKMWRQEEKMWEQEEKM----QEQEEKMQRQEEKMREQ 536
Query: 257 QKHL--QESRNDKEMLQLQ 273
+ L QE + ++ ++LQ
Sbjct: 537 EVRLWQQEEKMQEQEVRLQ 555
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 75.5 bits (184), Expect = 1e-13
Identities = 56/268 (20%), Positives = 134/268 (50%), Gaps = 8/268 (2%)
Query: 156 SAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFI 215
SA+ V+E+ N + Q+ + +QE +IQE + E +++E + K+ +Q+
Sbjct: 275 SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE--- 331
Query: 216 DVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFK 275
K+ E E++ E + K+ ++ ++ + + E + ++ R E +Q Q +
Sbjct: 332 ---EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
Query: 276 KIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALD 335
++ ++E+ ++ + + E D+ + ++EEE+ R ++ +ELE+ +
Sbjct: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
Query: 336 LLKREKEAQEQEFLSLQEEFQKLEK--ENLEERQKLKSRLEKLLTQVRNLQFMSENERTK 393
L+ +E ++E +QE+ +K+++ E ++E+++ R EKLL Q + E +
Sbjct: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ 508
Query: 394 NIKLQQQINEVKNENAKLKQQVARSEEQ 421
K+ +Q +++ + K+++Q + EQ
Sbjct: 509 EEKMWEQEEKMQEQEEKMQRQEEKMREQ 536
Score = 66.6 bits (161), Expect = 7e-11
Identities = 59/275 (21%), Positives = 139/275 (50%), Gaps = 32/275 (11%)
Query: 153 WEQSAESLQPVQEDMALNEV--------LQKLKHTNRKQEVRIQELQCSNLYLEKRVKEL 204
W Q E +Q +E M E+ + + + +QE +I+E + E++++E
Sbjct: 300 WRQE-EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358
Query: 205 QMKITKQQVFI-DVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQES 263
+ KI +Q+ + K++E E++ E + ++ ++ ++ + +E + +K ++E
Sbjct: 359 EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQ 418
Query: 264 ----RNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYL-EMDKTLSKKEEEVER 318
R +E + Q +KI+ E M + ++K + V + + E ++ + ++EE+++R
Sbjct: 419 DEKIREQEEEMWRQEEKIRE-----LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
Query: 319 LQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLT 378
++ +E E+ T LLK+E++ EQE E+ + E++ E+ +K++ + EK
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEK--- 525
Query: 379 QVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQ 413
+Q E R + ++L QQ +++ + +L++
Sbjct: 526 ----MQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Score = 58.2 bits (139), Expect = 2e-08
Identities = 89/503 (17%), Positives = 208/503 (41%), Gaps = 75/503 (14%)
Query: 149 EMPDWEQSAESLQPVQ---------EDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEK 199
E D +Q ESL+ V ED ++ V + + R +++ N K
Sbjct: 92 ESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRK 151
Query: 200 RV---------------KELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKK 244
RV K + + ++ + D ++ +E+L +++ + LE
Sbjct: 152 RVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTI 211
Query: 245 TLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLE 304
T + L+E A Q+ L+ ++K +QL K +K ER + Q Q L+
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL----ERAQLLLPQ------QQLQ 261
Query: 305 MDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLE 364
++ KE LQ + +L+ A +L + QE++ +E+ Q+ E++ E
Sbjct: 262 VEADRLGKE-----LQSVSAKLQ-AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCE 315
Query: 365 ERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYV 424
+ K++ + EK+ Q + E R + K+ +Q +++ + K+++Q + Q
Sbjct: 316 QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 425 PKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSL 484
+ + ++++Q EE+ + EE++ + KR ++ + +
Sbjct: 376 IREQDEKIQEQEEEMWRQ--------------------EEKIREQEEKRQEKMWRQEKKM 415
Query: 485 LALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSI 544
+ I + E +++ EK+ ++L+ + ++ +EV + +E + +
Sbjct: 416 RE------QDEKIREQEEEMWRQEEKI-----RELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 545 RDVPTLLGAKLDKYHSLNEEL---DFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLE 601
++ + + +K E+ + L+ E+I E ++++ ++ EE+ + E
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE-QEEKMWRQEEKMWEQEEKMQEQE 523
Query: 602 DLIRKPREKARKPRSKSLENHPK 624
+ +++ EK R+ + + K
Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEK 546
Score = 48.5 bits (114), Expect = 2e-05
Identities = 50/212 (23%), Positives = 106/212 (50%), Gaps = 12/212 (5%)
Query: 164 QEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFI-DVINKLK 222
+++ E + + + R+Q+ +I+E + E++++EL+ + Q+ + +V K++
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 223 ENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRN---DKEMLQLQFKKIKA 279
E E++ E + KI ++ + K +Q EE +K L++ +E + Q +K+
Sbjct: 459 EEEEKMQEQEEKI--QRQEEK--IQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE 514
Query: 280 NYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEK--ATASALDLL 337
+QE+ +Q+ K Q + + + K +E+ RLQ+L++ L K A L
Sbjct: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGA 574
Query: 338 KREKEAQEQEFLS--LQEEFQKLEKENLEERQ 367
RE +Q L+ LQ E + E ++L+++Q
Sbjct: 575 GRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606
Score = 31.6 bits (70), Expect = 2.4
Identities = 37/139 (26%), Positives = 68/139 (48%), Gaps = 17/139 (12%)
Query: 139 WRSEA-CRENCEMPDWEQSAESLQPVQEDMALNEV-LQKLKHTNRKQEVRIQELQCSNLY 196
WR E RE EM + E L+ V+E M E +Q+ + ++QE +IQE +
Sbjct: 430 WRQEEKIRELEEM--MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR 487
Query: 197 LEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANT 256
EK +K+ + KI +Q+ K+ E++ E + K+ + ++ +Q EE +
Sbjct: 488 QEKLLKQ-EEKIWEQE------EKMWRQEEKMWEQEEKM----QEQEEKMQRQEEKMREQ 536
Query: 257 QKHL--QESRNDKEMLQLQ 273
+ L QE + ++ ++LQ
Sbjct: 537 EVRLWQQEEKMQEQEVRLQ 555
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 75.1 bits (183), Expect = 2e-13
Identities = 127/578 (21%), Positives = 246/578 (42%), Gaps = 90/578 (15%)
Query: 109 EMSVSYEKEVTAEGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDMA 168
E+ +S E TA+ + + T +A + E + ++ +Q LQ QE +
Sbjct: 649 ELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQL---DQVTAKLQDKQEHCS 705
Query: 169 -LNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVE- 226
L L++ K E + +EL+ LE L++K +K+Q D+ + + N +
Sbjct: 706 QLESHLKEYKEKYLSLEQKTEELEGQIKKLE--ADSLEVKASKEQALQDLQQQRQLNTDL 763
Query: 227 --ELIEDKYKIILEK---NDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKI---- 277
E ++ +EK + T+ LQ E L + ++ L + +K++L+ F+ +
Sbjct: 764 ELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQET 823
Query: 278 KANYVCLQERY---MTEMQ----QKNKSVSQYLEMDKTLSKKEEEVERLQ-QLKKELEKA 329
K + L R +TE+Q +K +++ + LSK + ++ + + +KE +K
Sbjct: 824 KIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKG 883
Query: 330 TASALDL------LKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNL 383
A+ LDL LK + + Q + L Q+E +K ++ E +LK L + Q+
Sbjct: 884 KAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQA 943
Query: 384 QFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEE----- 438
Q + + +LQ INE+K + + K+Q+ + + + + +L+++L++
Sbjct: 944 QNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQA 1003
Query: 439 ------------VLKSDITKDTKT----------THSNLL---PDCSPCEERLNPAD--- 470
VL+++ K +T S LL D EE+L+ A
Sbjct: 1004 AQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDL 1063
Query: 471 IKRASQLASKMHSLLALMVGLLTC-QDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTL 529
I +Q+ ++ + L T QD + + + + + DI QK KSL
Sbjct: 1064 ISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDI--QKEKSLK------ 1115
Query: 530 DKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEEL-DFLVTSYEEIIECAD-------- 580
+KE++ +E + ++ + + + LNEEL + S +EI D
Sbjct: 1116 EKELV----NEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQ 1171
Query: 581 ----QRLAISHSQIAHLEERNKH-LEDLIRKPREKARK 613
Q A S E+RN+ L+D ++K E+ +K
Sbjct: 1172 KLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKK 1209
Score = 62.4 bits (150), Expect = 1e-09
Identities = 94/445 (21%), Positives = 194/445 (43%), Gaps = 26/445 (5%)
Query: 1 MTEKPEFQSQVYNYAKDNNIKQDSFKEENPMETSVSANTDQLGNEYFRQPPPRSPPLIHC 60
MTE + ++ + + F++EN + + ++ E Q + +
Sbjct: 852 MTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKE 911
Query: 61 SGEMLKFTEKSLAKSIAKESALNPSQPPSFLCKTAVPS---KEIQNYGEIPEMSVSYEKE 117
E+ K EK S + LN Q + + +E Q G I E+ S E++
Sbjct: 912 QKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQK 971
Query: 118 VTAEGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDMA-LNEVLQKL 176
+ +I + I+ + EN Q+A+ L +E ++ L +K
Sbjct: 972 -------KKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKS 1024
Query: 177 KHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKE--NVEELIED--K 232
+ T ++ + + L + +K ++ K++ Q D+I+ + N +LI++
Sbjct: 1025 QETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQE--DLISNRNQIGNQNKLIQELKT 1082
Query: 233 YKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYV-CLQERYMTE 291
K LE++ KK Q E A ++S +KE++ + K + + C QE+ +T+
Sbjct: 1083 AKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITK 1142
Query: 292 MQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSL 351
+ ++ KS LE K ++ ++ + L Q K EL+ S +++EK Q+ +
Sbjct: 1143 LNEELKS--HKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQV 1200
Query: 352 QEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIK---LQQQINEVKNEN 408
++E ++L+KE +E+ KL S +++ ++ + ENE ++ L + + VK E
Sbjct: 1201 KKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHE---ENEAKLTMQITALNENLGTVKKEW 1257
Query: 409 AKLKQQVARSEEQNYVPKFETAQLK 433
+++V+ E+Q + E A L+
Sbjct: 1258 QSSQRRVSELEKQTDDLRGEIAVLE 1282
Score = 49.7 bits (117), Expect = 8e-06
Identities = 87/442 (19%), Positives = 172/442 (38%), Gaps = 68/442 (15%)
Query: 252 VLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSK 311
+L + LQ S +++ + KK Y LQ++ S ++ +++ L +
Sbjct: 87 LLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEE 146
Query: 312 KEEEVERLQQLKKELEKATA----------SALDLLKREKEAQEQEFLSLQEEFQK---- 357
+ E ++Q+K E+ A S D + +EA EQ+ L EE K
Sbjct: 147 AQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATV 206
Query: 358 --------LEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTK----NIKLQQQINEVK 405
L++ +E+ LK L ++ T + N+ E E K KLQ Q +
Sbjct: 207 IQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSE 266
Query: 406 NENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLL---PDCSPC 462
++L+ ++A+ ++ V E +LK + E +T+ +T NLL D +
Sbjct: 267 ATISQLRSELAKGPQEVAVYVQELQKLKSSVNE-----LTQKNQTLTENLLKKEQDYTKL 321
Query: 463 EERLNPADIKR-----------------ASQLASKMHSLLALMVGLLTCQDIINSDAEHF 505
EE+ N + + S+L++ SL + V L + E
Sbjct: 322 EEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEEL 381
Query: 506 KESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEEL 565
E E + + K L +++ ++ + S ++ L L+ L E
Sbjct: 382 SEVETKYQHLKAEFKQLQQQREEKEQHGLQLQS-------EINQLHSKLLETERQLGEAH 434
Query: 566 DFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKP---REKARKPRSKSLENH 622
L +E + + ++L Q+A L+ + LE+ +++ + + K+ + H
Sbjct: 435 GRL----KEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQH 490
Query: 623 PKSMTMM---PALFKENRNDLD 641
+ + A +E +NDL+
Sbjct: 491 QEQQALQQSTTAKLREAQNDLE 512
Score = 49.7 bits (117), Expect = 8e-06
Identities = 84/476 (17%), Positives = 195/476 (40%), Gaps = 34/476 (7%)
Query: 164 QEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKE 223
QE + LQKLK + + + Q L + L E+ +L+ K ++ V K+
Sbjct: 281 QEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVS-------KK 333
Query: 224 NVEELIEDK----YKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKA 279
N++ + K ++ + ++ +L + L+ + Q+ + + ++ +++ +KA
Sbjct: 334 NIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKA 393
Query: 280 NYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEV-ERLQQLKKELEKATASALDLLK 338
+ LQ++ + Q + S+ ++ L + E ++ E +LK++ + ++ +D
Sbjct: 394 EFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMD--- 450
Query: 339 REKEAQEQEFLSLQEEFQKLE---KENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNI 395
+EQ+ LQ + +LE KE + +L+ +L+K Q + Q + ++ K
Sbjct: 451 -----KEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLR 505
Query: 396 KLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNL 455
+ Q + +V + Q++ E K + L+ + E++ + +T N
Sbjct: 506 EAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQ 565
Query: 456 LPDCS-PCEERLNPADIKRASQLASKMHSLLAL-------MVGLLTCQDIINSDAEHFKE 507
L + + +E++ K +Q S + L L QD + S E
Sbjct: 566 LQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNE 625
Query: 508 SEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDF 567
+ +K+ L ++ K + ++ ++ + D+ L + +EL+
Sbjct: 626 LNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNK 685
Query: 568 LVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKPRE---KARKPRSKSLE 620
+ T +++ + +HL+E + L +K E + +K + SLE
Sbjct: 686 ITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLE 741
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 74.3 bits (181), Expect = 3e-13
Identities = 109/566 (19%), Positives = 232/566 (40%), Gaps = 66/566 (11%)
Query: 99 KEIQNYGEIPEMSVSYEKEVTAEGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAE 158
+ N P M + ++ + + E + ++T + E + + + E+
Sbjct: 820 RSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLV 879
Query: 159 SLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKI---------- 208
+L VQE L +Q E R +L + LE ++KE+ +
Sbjct: 880 TL--VQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAEL 937
Query: 209 -TKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDK 267
K++ D ++LK+++++L K+ EK+ T+ ++NL E L+ + + + +K
Sbjct: 938 TAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREK 997
Query: 268 EMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELE 327
+ LQ ++ + ++Q + V+ ++KT SK E++VE L+ LE
Sbjct: 998 KALQE-----------AHQQALDDLQAEEDKVN---SLNKTKSKLEQQVE---DLESSLE 1040
Query: 328 KATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMS 387
+ +D L+R K E + QE LE ++Q+L RL+K + LQ
Sbjct: 1041 QEKKLRVD-LERNKRKLEGDLKLAQESILDLE----NDKQQLDERLKKKDFEYCQLQSKV 1095
Query: 388 ENERTKNIKLQQQINEVKNENAKLKQQV-------ARSEEQNYVPKFETAQLKDQLEEVL 440
E+E+T ++ Q++I E++ +L++++ A++E+Q E +L ++LEE
Sbjct: 1096 EDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEA- 1154
Query: 441 KSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLAS--KMHSLLALMVGLLTCQDII 498
+T + + L A ++ + +A+ K H+ D +
Sbjct: 1155 -GGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHA------------DSV 1201
Query: 499 NSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKY 558
E ++V + ++ L+ L + +A ++ + L +L +
Sbjct: 1202 AELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKA-NLEKICRTLEDQLSEA 1260
Query: 559 HSLNEELDFLVTSYEEIIECADQRLAISHSQIA-HLEERNKHLEDLIRKPREKARKPR-- 615
NEE+ ++ + RL +++ LEE+ + L R + ++
Sbjct: 1261 RGKNEEIQRSLSE----LTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEEL 1316
Query: 616 SKSLENHPKSMTMMPALFKENRNDLD 641
+ LE K+ + + +R+D D
Sbjct: 1317 KRQLEEENKAKNALAHALQSSRHDCD 1342
Score = 65.9 bits (159), Expect = 1e-10
Identities = 82/371 (22%), Positives = 164/371 (44%), Gaps = 59/371 (15%)
Query: 93 KTAVPSKEIQNYGEIPEMSVSYEKEVTAEGVERPEIVSTWSSAGISWRSEACRENCEMPD 152
K+ + K + EI ++ +Y++ V E + + A + R+EA R +M
Sbjct: 1570 KSEIDRKIAEKDEEIEQLKRNYQRTV--------ETMQSALDAEVRSRNEAIRLKKKM-- 1619
Query: 153 WEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQC-------SNLYLEKRVKELQ 205
+ LNE+ +L H NR+ ++ L+ + L+L+ ++ Q
Sbjct: 1620 -------------EGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRG-Q 1665
Query: 206 MKITKQQVFIDV-INKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESR 264
+ +Q ++ N L+ VEEL + LE+ + + L E + +N + L ++
Sbjct: 1666 EDLKEQLAIVERRANLLQAEVEEL-----RATLEQTERARKLAEQELLDSNERVQLLHTQ 1720
Query: 265 ND-----KEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERL 319
N K+ L+ ++++ ++ K+++ M + L K+++ L
Sbjct: 1721 NTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1780
Query: 320 QQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKE------NLEERQKLKSR- 372
+++KK LE+ DL R EA++ +++ QKLE LE QK +
Sbjct: 1781 ERMKKNLEQTVK---DLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTES 1837
Query: 373 ---LEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQ--NYVPKF 427
L K +V+ L + SE +R ++LQ +++++ + K+Q ++EQ ++ KF
Sbjct: 1838 VKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKF 1897
Query: 428 ETAQLKDQLEE 438
AQ +LEE
Sbjct: 1898 RKAQ--HELEE 1906
Score = 63.9 bits (154), Expect = 4e-10
Identities = 107/543 (19%), Positives = 218/543 (40%), Gaps = 80/543 (14%)
Query: 154 EQSAESLQPVQEDM----ALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKIT 209
+Q+ E + ++E+ AL LQ +H + +E Q L++ + + ++
Sbjct: 1311 QQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVA 1370
Query: 210 KQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEM 269
+ + + + EEL E K K+ D+++ ++ + A+ +K Q + + E
Sbjct: 1371 QWRTKYET--DAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVED 1428
Query: 270 LQLQFKKIKANYVCLQERYMTE----MQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKE 325
L + ++ + L ++ + K K E++ +L + L +LK
Sbjct: 1429 LMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNA 1488
Query: 326 LEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLE-ERQKLKSRLEKLLTQV--RN 382
E+A L+ +KRE + EQE L E+ + K E E+ + + LEK Q+
Sbjct: 1489 YEEAL-DQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEE 1547
Query: 383 LQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQ------NYVPKFETAQ----- 431
+ E+E K +++Q ++ +VK+E + +++A +E+ NY ET Q
Sbjct: 1548 AEAALEHEEAKILRIQLELTQVKSE---IDRKIAEKDEEIEQLKRNYQRTVETMQSALDA 1604
Query: 432 ----------LKDQLE------------------EVLK-----SDITKDTKTTHSNLLPD 458
LK ++E E LK KDT+ + L
Sbjct: 1605 EVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRG 1664
Query: 459 CSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQK 518
+E+L + +RA+ L +++ L A + + + ++ E +E+V + Q
Sbjct: 1665 QEDLKEQLAIVE-RRANLLQAEVEELRATLEQTERARKL--AEQELLDSNERVQLLHTQN 1721
Query: 519 LKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIEC 578
+H KKK L+ +++ S+ + RD + E+ +T + E
Sbjct: 1722 TSLIHTKKK-LETDLMQLQSEVEDASRDA-----------RNAEEKAKKAITDAAMMAE- 1768
Query: 579 ADQRLAISHSQIAHLEERNKHLEDLIRKPREKARKPRSKSLENHPKSMTMMPALFKENRN 638
L AHLE K+LE ++ + + + +L+ K + + +E
Sbjct: 1769 ---ELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEF 1825
Query: 639 DLD 641
+L+
Sbjct: 1826 ELE 1828
Score = 61.6 bits (148), Expect = 2e-09
Identities = 89/476 (18%), Positives = 186/476 (39%), Gaps = 56/476 (11%)
Query: 6 EFQSQVYNYAKDNNIKQDSFKEENPMETSVSANTDQLGNEYFRQPPPRSPPLIHCSGEML 65
+FQ ++ K+ + + +EE E + A T++ ++Y R+ S L G
Sbjct: 1104 QFQKKI----KELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVT- 1158
Query: 66 KFTEKSLAKSIAKESALNPSQPPSFL-CKTAVPSKEIQNYGEIPEMSVSYEKEVTAEGVE 124
+ + LN + FL + + +Q+ + + + V G
Sbjct: 1159 -----------STQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELG-- 1205
Query: 125 RPEIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDM-----ALNEVLQKLKHT 179
E + E E+ D S ES+ + ++ L + L + +
Sbjct: 1206 --EQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGK 1263
Query: 180 NRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEK 239
N + + + EL L+ EL ++ +++ + +++ K+ + E+ + + E+
Sbjct: 1264 NEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEE 1323
Query: 240 NDTKKTL----QNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMT----- 290
N K L Q+ ++ +E + K LQ K + + +Y T
Sbjct: 1324 NKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 1383
Query: 291 --EMQQKNKSVSQYLE---------------MDKTLSKKEEEVERLQQLKKELEKATASA 333
E+++ K ++Q L+ ++KT + + EVE L + E + A+A
Sbjct: 1384 TEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLM-VDVERANSLAAA 1442
Query: 334 LDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTK 393
LD +R + E+ + EE Q + +L+E + L + L KL E + +
Sbjct: 1443 LDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRE 1502
Query: 394 NIKLQQQINEVKN---ENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITK 446
N L+Q+I ++ EN K ++ +S +Q + K + ++ E L+ + K
Sbjct: 1503 NKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAK 1558
Score = 48.1 bits (113), Expect = 2e-05
Identities = 81/378 (21%), Positives = 161/378 (42%), Gaps = 66/378 (17%)
Query: 269 MLQLQFKKI---KANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKE 325
+++++F+K+ + + C+Q + M K+ + K L K E + + +K+E
Sbjct: 797 LMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEE 856
Query: 326 LEKATASALDLLKREKEAQEQEFLSLQEEFQ-----KLEKENL---EER--QKLKSRLEK 375
+K + KE +E+ +QE+ + E ENL EER Q +K++ +
Sbjct: 857 FQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQ- 915
Query: 376 LLTQVRNLQFMSENER-------TKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFE 428
L +++ + +E+E K KL+ + +E+K + L+ +A+ E++ + + +
Sbjct: 916 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 975
Query: 429 TAQLKDQLE--EVLKSDITKDTKT---THSNLLPDCSPCEERLNPADIKRASQLASKMHS 483
L ++L + + +T++ K H L D E+++N + K S+L ++
Sbjct: 976 VKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLN-KTKSKLEQQV-- 1032
Query: 484 LLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLK-SLHLKKKTLDKEVIDCDSDEAK 542
D E E EK + L++ K L K + ++D ++D+ +
Sbjct: 1033 ----------------EDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQ 1076
Query: 543 SIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAIS-HSQIAHLEERNKHLE 601
L +L K DF + +E +Q L + +I L+ R + LE
Sbjct: 1077 --------LDERLKK-------KDFEYCQLQSKVE-DEQTLGLQFQKKIKELQARIEELE 1120
Query: 602 DLI---RKPREKARKPRS 616
+ I R R K K RS
Sbjct: 1121 EEIEAERATRAKTEKQRS 1138
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 74.3 bits (181), Expect = 3e-13
Identities = 106/565 (18%), Positives = 248/565 (43%), Gaps = 73/565 (12%)
Query: 99 KEIQNYGEIPEMSVSYEKEVTAEGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAE 158
+ N P M + ++ + + E + ++T + E + + + E+
Sbjct: 822 RAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMV 881
Query: 159 SLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKI---------- 208
+L + D+ L +Q + E R ++L + + LE ++KE+ +
Sbjct: 882 TLLKEKNDLQLQ--VQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAEL 939
Query: 209 -TKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDK 267
K++ D ++LK+++++L K+ EK+ T+ ++NL E +A + + + +K
Sbjct: 940 TAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEK 999
Query: 268 EMLQ---------LQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVER 318
+ LQ LQ ++ K N + + T+++Q+ + LE +K L E +R
Sbjct: 1000 KALQETHQQTLDDLQAEEDKVN---ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKR 1056
Query: 319 LQQLKKELEKATASALDLLKREK---EAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEK 375
+L+ +L+ A S +D+ ++ E E++ + K+E E E Q L+ ++++
Sbjct: 1057 --KLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQ-LQKKIKE 1113
Query: 376 LLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQV-------ARSEEQNYVPKFE 428
L ++ L E ER K ++Q +++ E ++ +++ + E N + E
Sbjct: 1114 LQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAE 1173
Query: 429 TAQLKDQLEE--VLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLA 486
+L+ LEE + + + H++ + + E+++ +++R Q K S L
Sbjct: 1174 FQKLRRDLEEATLQHEAMVAALRKKHADSMAELG---EQID--NLQRVKQKLEKEKSELK 1228
Query: 487 LMVGLLTCQDIINSDAEHFKES----EKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAK 542
+ D ++S+AE ++ EK+ + ++ L K++ + + D + A+
Sbjct: 1229 MET------DDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRAR 1282
Query: 543 SIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRL-AISH---------SQIAH 592
L + +Y +E D LV+ + + Q++ + H + +AH
Sbjct: 1283 --------LQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAH 1334
Query: 593 LEERNKHLEDLIRKPREKARKPRSK 617
+ ++H DL+R+ E+ ++ +++
Sbjct: 1335 ALQSSRHDCDLLREQYEEEQEGKAE 1359
Score = 66.2 bits (160), Expect = 9e-11
Identities = 73/298 (24%), Positives = 140/298 (46%), Gaps = 42/298 (14%)
Query: 169 LNEVLQKLKHTNRKQEVRIQE-------LQCSNLYLEKRVKELQMKITKQQVFIDV-INK 220
LNE+ +L H NR ++ L+ + L+L+ ++ Q + +Q ++ N
Sbjct: 1625 LNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRG-QEDLKEQLAIVERRANL 1683
Query: 221 LKENVEEL------IEDKYKI----ILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEML 270
L+ +EEL E KI +L+ ++ + L L NT+K L+ ND L
Sbjct: 1684 LQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE---NDVSQL 1740
Query: 271 QLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKAT 330
Q + +++ +QE E + K K+++ M + L K+++ L+++KK LE+
Sbjct: 1741 QSEVEEV------IQESRNAEEKAK-KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV 1793
Query: 331 ASALDLLKREKEAQEQEFLSLQEEFQKLEKE------NLEERQKLKSR----LEKLLTQV 380
DL R EA++ +++ QKLE +E QK + L K +V
Sbjct: 1794 K---DLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRV 1850
Query: 381 RNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEE 438
+ L + +E +R ++LQ +++++ + K+Q +EEQ+ + +L+ +LEE
Sbjct: 1851 KELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEE 1908
Score = 61.2 bits (147), Expect = 3e-09
Identities = 67/321 (20%), Positives = 137/321 (42%), Gaps = 32/321 (9%)
Query: 149 EMPDWEQSAESLQPVQEDM-----ALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKE 203
E D +AE++ + ++ +L + + +LK +Q+ I +L L+ E
Sbjct: 1230 ETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGE 1289
Query: 204 LQMKITKQQVFIDVINKLKENVEELIED-KYKIILE---KNDTKKTLQNLEEVLANTQKH 259
++ ++ + +++ K+ + IE+ K+++ E KN LQ+ ++
Sbjct: 1290 YSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQ 1349
Query: 260 LQESRNDKEMLQLQFKKIKANYVCLQERYMT-------EMQQKNKSVSQYLE-------- 304
+E + K LQ K + + +Y T E+++ K ++Q L+
Sbjct: 1350 YEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEA 1409
Query: 305 -------MDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQK 357
++KT + + EVE L L E A +ALD +R + E+ EE Q
Sbjct: 1410 VNAKCASLEKTKQRLQNEVEDLM-LDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQA 1468
Query: 358 LEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVAR 417
+ + +E + L + L K+ E R +N LQQ+I+++ + A+ +Q+
Sbjct: 1469 ELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHE 1528
Query: 418 SEEQNYVPKFETAQLKDQLEE 438
E+ + E +++ LEE
Sbjct: 1529 LEKIKKQVEQEKCEIQAALEE 1549
Score = 58.2 bits (139), Expect = 2e-08
Identities = 120/569 (21%), Positives = 235/569 (41%), Gaps = 88/569 (15%)
Query: 100 EIQNYGEIPEMSVSYEK---EVTAEGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQS 156
EIQ +I E+ E+ E+ AE R + RS+ RE E+ + +
Sbjct: 1104 EIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ--------RSDLSRELEEISERLEE 1155
Query: 157 AESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFID 216
A Q ++ N+K+E Q+L+ E ++ M ++ D
Sbjct: 1156 AGGATSAQVEL------------NKKREAEFQKLRRD--LEEATLQHEAMVAALRKKHAD 1201
Query: 217 VINKLKENVEELIEDKYKIILEKNDTK--------------KTLQNLEEVLANTQKHLQE 262
+ +L E ++ L K K+ EK++ K K NLE++ + + + E
Sbjct: 1202 SMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSE 1261
Query: 263 SRNDKEMLQLQFKKIKANYVCLQER---YMTEMQQKNKSVSQYLEMDKTLSKKEEEVERL 319
+ +E Q + A LQ Y ++ +K+ VSQ K+ +++
Sbjct: 1262 LKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSR------SKQASTQQI 1315
Query: 320 QQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQ 379
++LK +LE+ T + K A S + + L +E EE Q+ K+ L++ L++
Sbjct: 1316 EELKHQLEEET--------KAKNALAHALQSSRHDCDLL-REQYEEEQEGKAELQRALSK 1366
Query: 380 VRN--LQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQL---KD 434
+ Q+ ++ E T I+ +++ E K KL Q++ +EE + A L K
Sbjct: 1367 ANSEVAQWRTKYE-TDAIQRTEELEEAKK---KLAQRLQEAEEHVEAVNAKCASLEKTKQ 1422
Query: 435 QLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTC 494
+L+ ++ D+ D + +++ C+ +++ D K S+ K A L
Sbjct: 1423 RLQNEVE-DLMLDVERSNA----ACAALDKKQRNFD-KVLSEWKQKYEETQA---ELEAS 1473
Query: 495 QDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAK 554
Q S + + + V + L +L++L + K L +E+ D A+ G +
Sbjct: 1474 QKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEG--------GKQ 1525
Query: 555 LDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLE-ERNKHLEDLIRKPREKARK 613
+ + + ++++ + +E A+ L +I ++ E N+ ++ RK EK +
Sbjct: 1526 IHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEE 1585
Query: 614 PRSKSLENHPKSM-TMMPALFKE--NRND 639
+ NH + + TM L E +RND
Sbjct: 1586 -IDQLKRNHTRVVETMQSTLDAEIRSRND 1613
Score = 50.1 bits (118), Expect = 6e-06
Identities = 64/254 (25%), Positives = 114/254 (44%), Gaps = 37/254 (14%)
Query: 169 LNEVLQKLKHTNRKQEV----------RIQELQCSNLYLEKRVKELQMKITKQQVFIDVI 218
+ E+ L+ T R +++ R+Q L N L K+L+ +++ Q ++ +
Sbjct: 1688 IEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEV 1747
Query: 219 NKLKENVEE----LIEDKYKIILE---KNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQ 271
+ N EE I D + E + DT L+ +++ L T K LQ ++ E L
Sbjct: 1748 IQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLA 1807
Query: 272 L-----QFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMD---KTLSKKEEE----VERL 319
L Q +K++A L+ E ++ ++V + + K L+ + EE V RL
Sbjct: 1808 LKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRL 1867
Query: 320 QQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQ 379
Q L +L+ S KR+ E E++ + +F+KL+ E LEE ++ R + +Q
Sbjct: 1868 QDLVDKLQAKVKS----YKRQAEEAEEQSNANLSKFRKLQHE-LEEAEE---RADIAESQ 1919
Query: 380 VRNLQFMSENERTK 393
V L+ S TK
Sbjct: 1920 VNKLRVKSREVHTK 1933
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 73.9 bits (180), Expect = 4e-13
Identities = 133/631 (21%), Positives = 257/631 (40%), Gaps = 123/631 (19%)
Query: 63 EMLKFTEKSLAKS----IAKESALNPSQPPSFLCKT------AVPSKEIQNYGEIPEMSV 112
+ +K TE SLA +KE L Q +FL K A+ +++ E+ +M
Sbjct: 614 KQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQ 673
Query: 113 SY----------EKEVTAEGVERPEIVSTWSSAGISWRSEACRENC---EMPDWEQSAES 159
S E+++ E + E + + +SE + E P+ + +
Sbjct: 674 SVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQM 733
Query: 160 LQPVQEDMALNEVLQKLKHTNRKQ----EVRIQELQCSNLYLEKRVKELQMKITKQQVFI 215
+ +QE + +++L T Q E + ++ N L K V++L+ K Q F
Sbjct: 734 EKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFA 793
Query: 216 DVINKLKE----------NVEELIEDKYKIILEKNDT----------------------- 242
++ +LK+ +VEEL+E + + K T
Sbjct: 794 SLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQM 853
Query: 243 ---KKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSV 299
K L+ E+ LANT K LQ+ + + E L+ +++ + + ++ S
Sbjct: 854 NTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNL-----------KEASSA 902
Query: 300 SQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLE 359
SQ+ E++ L +KE E++RL+ + KE E +S LL ++ Q++ L + + ++L+
Sbjct: 903 SQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLL---QDVQDENKL-FKSQIEQLK 958
Query: 360 KENL---------EERQKLKSRLEK----LLTQVRNLQFMSENERTKNIKLQQQINEVKN 406
++N EE K+ S EK L ++ +L+ E++R KN N+++
Sbjct: 959 QQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKN-------NDLRE 1011
Query: 407 ENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERL 466
+N + + +A +E+ +T++ + Q E + + K L P S
Sbjct: 1012 KNWEAMEALASTEKMLQDKVNKTSKERQQQVEA----VELEAKEVLKKLFPKVSV----- 1062
Query: 467 NPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEH-FKESEKVSDIMLQKLKSLHLK 525
P+++ L M G +++ EH KE++++ ++ + + K
Sbjct: 1063 -PSNLSYGEWLHGFEKKAKECMAGTSGSEEV--KVLEHKLKEADEMHTLLQLECE----K 1115
Query: 526 KKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAI 585
K++ E +S+ K+D+ H +++ TS E+ +E RL
Sbjct: 1116 YKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELE----RLRS 1171
Query: 586 SHSQIAHLEERNKHLEDLIRKPREKARKPRS 616
+ I +L +HLE EKA RS
Sbjct: 1172 ENKDIENLRREREHLE----MELEKAEMERS 1198
Score = 62.8 bits (151), Expect = 1e-09
Identities = 100/515 (19%), Positives = 234/515 (45%), Gaps = 52/515 (10%)
Query: 154 EQSAESLQPVQEDMA--LNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQ 211
+QSAE L +++D A +NE+ +K +++EV+ + + + L+ +++E + + +
Sbjct: 443 KQSAE-LNKLRQDYARLVNELTEKTGKL-QQEEVQKKNAEQAATQLKVQLQEAERRWEEV 500
Query: 212 QVFIDVINKLKENVEELIEDKY--------KIILEKNDTKKTLQNLEEVLANTQKHLQES 263
Q +I E ++ ++ K+ + + DT + Q LE+ L + Q+
Sbjct: 501 QSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKR 560
Query: 264 RNDKEMLQLQFKKIKANYVCLQ---ERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQ 320
N +E LQ+Q + I L+ +++ +++ + + E+ K +++K++++++ +
Sbjct: 561 VNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTE 620
Query: 321 -QLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLE---KENLEERQKLKSRLEKL 376
L E ++ T+ +L K+ Q FL L+ E QKL+ E +L+ + +
Sbjct: 621 DSLASERDRLTSKEEEL----KDIQNMNFL-LKAEVQKLQALANEQAAAAHELEKMQQSV 675
Query: 377 LTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQL 436
+ ++ + E + + ++ + ++N LK +V + Q V + + +Q+
Sbjct: 676 YVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKL--QTLVSEQPNKDVVEQM 733
Query: 437 EEVL--KSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTC 494
E+ + K + K + L + EE LN + +S L ++ L A
Sbjct: 734 EKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSS-LTKEVQDLKAK------- 785
Query: 495 QDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAK 554
Q+ S A +E +KV K+KS+ ++ L+ E++ + E + V + +K
Sbjct: 786 QNDQVSFASLVEELKKVIHEKDGKIKSV---EELLEAELLKVANKE----KTVQLSITSK 838
Query: 555 LDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKPREKARKP 614
+ + +L + + + + + ++E ++ LA + + L+E N+ L+ +++ + K
Sbjct: 839 VQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKE 898
Query: 615 RSKS---------LENHPKSMTMMPALFKENRNDL 640
S + L+ + + A+ KE +DL
Sbjct: 899 ASSASQFEELEIVLKEKENELKRLEAMLKERESDL 933
Score = 52.0 bits (123), Expect = 2e-06
Identities = 87/405 (21%), Positives = 175/405 (43%), Gaps = 68/405 (16%)
Query: 64 MLKFTEKSLAKSIAKESALNPSQPPSFLCKTAVPSKEIQNYGEIPEMSVSYEKEVTAEGV 123
MLK E L+ +K L Q + L K+ + + QNY + +E+ +
Sbjct: 925 MLKERESDLS---SKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFP-PHEELLKVISE 980
Query: 124 ERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQ 183
EI W+ S + + + D E E +A E + + K N+
Sbjct: 981 REKEISGLWNELD-SLKDAVEHQRKKNNDLR---EKNWEAMEALASTEKMLQDK-VNKTS 1035
Query: 184 EVRIQELQCSNLYLEKRVKELQMKIT--KQQVFIDVINKLKENVEELI-----EDKYKII 236
+ R Q+++ L ++ +K+L K++ + + ++ ++ +E + ++ K++
Sbjct: 1036 KERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVL 1095
Query: 237 ---LEKNDTKKTLQNLE-----EVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERY 288
L++ D TL LE VLA T+ LQ+ + E + ++K
Sbjct: 1096 EHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWK------------- 1142
Query: 289 MTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEF 348
++ + +K++ Q M + + E+E+ERL+ K++E L+RE+E
Sbjct: 1143 -VKVDESHKTIKQ---MQSSFTSSEQELERLRSENKDIEN--------LRRERE------ 1184
Query: 349 LSLQEEFQKLEKEN---LEERQKLKSRLEKLLTQVRNLQFMSENERTKNI----KLQQQI 401
L+ E +K E E + E ++LK++L + LT++R +NER K K QQ +
Sbjct: 1185 -HLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRT----EQNERQKVAGDLHKAQQSL 1239
Query: 402 NEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITK 446
++++ K E + P+ E+++ K+ + L +T+
Sbjct: 1240 ELIQSKIVKAAGDTTVIENSDVSPETESSE-KETMSVSLNQTVTQ 1283
Score = 30.8 bits (68), Expect = 4.0
Identities = 30/181 (16%), Positives = 76/181 (41%), Gaps = 17/181 (9%)
Query: 197 LEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANT 256
L+K + ++ + K +V +D +K + ++ + + K ++NL +
Sbjct: 1127 LQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHL 1186
Query: 257 QKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEV 316
+ L+++ ++ + +++KA + TE ++ K L K ++ +
Sbjct: 1187 EMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGD-------LHKAQQSL 1239
Query: 317 ERLQ-QLKKELEKATASALDLLKREKEAQEQEFLS---------LQEEFQKLEKENLEER 366
E +Q ++ K T + E E+ E+E +S LQ+ Q + ++ +E+
Sbjct: 1240 ELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEK 1299
Query: 367 Q 367
+
Sbjct: 1300 E 1300
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 73.9 bits (180), Expect = 4e-13
Identities = 105/542 (19%), Positives = 243/542 (44%), Gaps = 45/542 (8%)
Query: 108 PEMSVSYEKEVTAEGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDM 167
P M + ++ + + ER + +++ + + + E+ SL + D+
Sbjct: 828 PWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 168 ALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKI-----------TKQQVFID 216
L +Q + E R +L + + LE +VKE+ ++ K++ D
Sbjct: 888 QLQ--VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLED 945
Query: 217 VINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKK 276
++LK ++++L K+ EK+ T+ ++NL E +A + + + +K+ LQ ++
Sbjct: 946 ECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005
Query: 277 IKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELE---KATASA 333
+ +++ T + K K Q +++ +L ++++ L++ K++LE K T +
Sbjct: 1006 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 1065
Query: 334 LDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEK----LLTQVRNLQFMSEN 389
+ L+ +K+ ++ E L +E+ Q L S+L+K L ++ L+ E
Sbjct: 1066 IMDLENDKQQLDERLKKKDFELNAL-NARIEDEQALGSQLQKKLKELQARIEELEEELEA 1124
Query: 390 ERTKNIKLQQQINEVKNENAKLKQQVARSE-------EQNYVPKFETAQLKDQLEE-VLK 441
ERT K+++ +++ E ++ +++ + E N + E +++ LEE L+
Sbjct: 1125 ERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQ 1184
Query: 442 SDITKDT-KTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLT--CQDII 498
+ T + H++ + + E+++ +++R Q K S L + +T + II
Sbjct: 1185 HEATAAALRKKHADSVAELG---EQID--NLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1239
Query: 499 NSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKY 558
+ A EK+ + ++ K + + V D S AK ++ L +LD+
Sbjct: 1240 KAKA----NLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK-LQTENGELSRQLDEK 1294
Query: 559 HSLNEELDFLVTSYEEIIECADQRL---AISHSQIAHLEERNKHLEDLIRKPREKARKPR 615
+L +L +Y + +E ++L + + +AH + +H DL+R+ E+ + +
Sbjct: 1295 EALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAK 1354
Query: 616 SK 617
++
Sbjct: 1355 AE 1356
Score = 70.1 bits (170), Expect = 6e-12
Identities = 122/551 (22%), Positives = 234/551 (42%), Gaps = 128/551 (23%)
Query: 165 EDMA-LNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKE 223
E+MA L+E++ KL K++ +QE ++ + +LQ + K KL++
Sbjct: 980 EEMAGLDEIIAKLT----KEKKALQEAH------QQALDDLQAEEDKVNTLTKAKVKLEQ 1029
Query: 224 NVEEL---IEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKAN 280
V++L +E + K+ + D ++ + LE L TQ+ + + NDK+ L + KK
Sbjct: 1030 QVDDLEGSLEQEKKV---RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 1086
Query: 281 YVCLQERY-------------MTEMQQKNKSVSQYLEMDKT-----------LSKKEEEV 316
L R + E+Q + + + + LE ++T LS++ EE+
Sbjct: 1087 LNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI 1146
Query: 317 -ERL---------------------QQLKKELEKAT----ASALDLLKREKEAQE---QE 347
ERL Q+++++LE+AT A+A L K+ ++ ++
Sbjct: 1147 SERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQ 1206
Query: 348 FLSLQEEFQKLEKE-------------NLEERQKLKSRLEKLLTQVRNLQFMSENERTKN 394
+LQ QKLEKE N+E+ K K+ LEK+ R L+ R+K
Sbjct: 1207 IDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKM---CRTLEDQMNEHRSKA 1263
Query: 395 IKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLE--EVLKSDITKDTKTTH 452
+ Q+ +N++ ++ AKL+ E +L QL+ E L S +T+ K T+
Sbjct: 1264 EETQRSVNDLTSQRAKLQT--------------ENGELSRQLDEKEALISQLTRG-KLTY 1308
Query: 453 SNLLPDCSPCEERLNPADIKRASQLASKMHSLLAL-------MVGLLTCQDIIN-SDAEH 504
+ L D E A A L S H L Q +++ +++E
Sbjct: 1309 TQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEV 1368
Query: 505 FKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDK-YHSLNE 563
+ K +Q+ + L KK L + + EA+ + + L+K H L
Sbjct: 1369 AQWRTKYETDAIQRTEELEEAKKKLAQRL-----QEAEEAVEAVNAKCSSLEKTKHRLQN 1423
Query: 564 ELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKPREKARKPRSKSLENHP 623
E++ L+ E S++ A L+++ ++ + ++ + ++K + +S+ +
Sbjct: 1424 EIEDLMVDVER-----------SNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1472
Query: 624 KSMTMMPALFK 634
++ ++ LFK
Sbjct: 1473 EARSLSTELFK 1483
Score = 67.4 bits (163), Expect = 4e-11
Identities = 94/500 (18%), Positives = 207/500 (41%), Gaps = 38/500 (7%)
Query: 145 RENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKEL 204
+ N E+ W E+ +Q L E +KL ++ E ++ + LEK L
Sbjct: 1363 KANSEVAQWRTKYET-DAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRL 1421
Query: 205 QMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESR 264
Q +I + + +DV + N DK ++ + K L ++ +Q L+ S+
Sbjct: 1422 QNEI--EDLMVDV---ERSNAAAAALDK-----KQRNFDKILAEWKQKYEESQSELESSQ 1471
Query: 265 NDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKK 324
+ L + K+K Y E T ++ + ++ + L + + L++++K
Sbjct: 1472 KEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRK 1531
Query: 325 ELE---KATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVR 381
+LE SAL+ + E +E + L Q EF +++ E +KL + E++ R
Sbjct: 1532 QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK---AEIERKLAEKDEEMEQAKR 1588
Query: 382 NLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLK 441
N + ++ +T + NE K++ + E Q A+ + Q++ +
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSL-- 1646
Query: 442 SDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSD 501
+ KDT+ + + +E + + +R + L +++ L A++ + + ++
Sbjct: 1647 QSLLKDTQIQLDDAVRANDDLKENIAIVE-RRNNLLQAELEELRAVVEQTERSRKL--AE 1703
Query: 502 AEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSL 561
E + SE+V + Q ++ KKK +D ++ ++ +++++ +
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKK-MDADLSQLQTEVEEAVQEC-----------RNA 1751
Query: 562 NEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKPREKARKPRSKSLEN 621
E+ +T + E L AHLE K++E I+ + + + +L+
Sbjct: 1752 EEKAKKAITDAAMMAE----ELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKG 1807
Query: 622 HPKSMTMMPALFKENRNDLD 641
K + + A +E N+L+
Sbjct: 1808 GKKQLQKLEARVRELENELE 1827
Score = 66.6 bits (161), Expect = 7e-11
Identities = 98/457 (21%), Positives = 202/457 (44%), Gaps = 71/457 (15%)
Query: 23 DSFKEENP-METSVSANTDQLGNEYFRQPPPRSPPLIHCSGEMLKFTEKSLAKSIAKESA 81
++FK EN ++ +S T+QLG+ S IH E+ K ++ A+ + +SA
Sbjct: 1496 ETFKRENKNLQEEISDLTEQLGS---------SGKTIH---ELEKVRKQLEAEKMELQSA 1543
Query: 82 LNPSQPPSFLCKTAVPSKEIQNYGEIPEMSVSYEKEVTAEGVERPEIVSTWSSAGISWRS 141
L ++ K ++ E ++ E+++ + E
Sbjct: 1544 LEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKDEEM---------------E 1584
Query: 142 EACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRV 201
+A R + + D Q++ + + AL V +K++ + E+++ +K+V
Sbjct: 1585 QAKRNHLRVVDSLQTSLDAETRSRNEALR-VKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 202 KELQMKITKQQVFID----VINKLKENVEELIEDKYKII---LEK-----NDTKKTLQNL 249
K LQ + Q+ +D + LKEN+ ++E + ++ LE+ T+++ +
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDLKENIA-IVERRNNLLQAELEELRAVVEQTERSRKLA 1702
Query: 250 EEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQ-------KNKSVSQY 302
E+ L T + +Q + L Q KK+ A+ LQ +Q+ K+++
Sbjct: 1703 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDA 1762
Query: 303 LEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLE--- 359
M + L K+++ L+++KK +E+ DL R EA++ +++ QKLE
Sbjct: 1763 AMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLDEAEQIALKGGKKQLQKLEARV 1819
Query: 360 ---KENLEERQKLKSR----LEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLK 412
+ LE QK + + K +++ L + +E +R ++LQ +++++ + K
Sbjct: 1820 RELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYK 1879
Query: 413 QQVARSEEQ--NYVPKFETAQLK-DQLEEVLKSDITK 446
+Q +EEQ + KF Q + D+ EE ++DI +
Sbjct: 1880 RQAEEAEEQANTNLSKFRKVQHELDEAEE--RADIAE 1914
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 73.6 bits (179), Expect = 5e-13
Identities = 124/553 (22%), Positives = 233/553 (42%), Gaps = 116/553 (20%)
Query: 156 SAESLQPVQEDMALNE-----VLQKLKH--TNRKQEVRIQELQCSNLYLEKRVKELQMKI 208
+A L+ +Q+ + + + + ++L+H +N+ +E +I L N L+ V++LQ +
Sbjct: 664 AAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKI--LNDQNKALKSEVQKLQTLV 721
Query: 209 TKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEV----LANTQKHLQESR 264
++Q NK +++E K I EK++ KT++ L E +A ++ L R
Sbjct: 722 SEQP------NK------DVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIR 769
Query: 265 NDKEMLQLQFKKIKA------NYVCLQERYMTEMQQKN---KSVSQYLEMDKTLSKKEEE 315
+ L + + +KA ++ L E + +K+ KSV + LE + L K +
Sbjct: 770 TENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE--LLKVANK 827
Query: 316 VERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEK 375
+ +Q LK+E+ KA + ++ EK AQ+ S +E Q L K E+ +K+ LE+
Sbjct: 828 EKTVQDLKQEI-KALKEEIGNVQLEK-AQQLSITSKVQELQNLLKGKEEQMNTMKAVLEE 885
Query: 376 LLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQ 435
+ N ++ + +N L+ + EV N K ++ EE V K + +LK +
Sbjct: 886 KEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELK-R 944
Query: 436 LEEVLK---SDITKDTKTTHSNLLPDCSPCE-------ERLNPADIKRASQLASKMHSLL 485
LE +LK SD++ T+ LL D E+L + ++AS L
Sbjct: 945 LEAMLKERESDLSSKTQ-----LLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLK 999
Query: 486 AL------MVGLLTCQDIINSDAEH--FKESEKVSDIMLQKLKSLHLKKKT--------- 528
+ + GL D + EH K +E+ + +L++ + KK
Sbjct: 1000 VISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSN 1059
Query: 529 ---------LDKEVIDC-----DSDEAKSIR-------DVPTLLGAKLDKYHSLNEELDF 567
+K+ +C S+E K + ++ TLL + +KY S+ E +
Sbjct: 1060 LSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEG 1119
Query: 568 LVTSYEEIIECADQRLAI------------------SHSQIAHLEERNKHLEDLIRKPR- 608
++ + +E + + + S ++ L NK +E+L R+
Sbjct: 1120 ILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREH 1179
Query: 609 -----EKARKPRS 616
EKA RS
Sbjct: 1180 LEMELEKAEMERS 1192
Score = 65.5 bits (158), Expect = 1e-10
Identities = 106/542 (19%), Positives = 223/542 (41%), Gaps = 102/542 (18%)
Query: 145 RENCEMPDWEQSAESL--QPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVK 202
+E + + EQ+A L Q + + EV ++ + E Q+LQ + E V+
Sbjct: 471 QEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQ 530
Query: 203 ELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQE 262
L K+T V +L++ + +L+E + K + N EE L Q +Q+
Sbjct: 531 SLHSKLTDTLVSKQ---QLEQRLMQLMESEQKRV-----------NKEESL---QMQVQD 573
Query: 263 SRNDKEMLQLQFKKIKANYVC------LQERYMTEMQQKNKSVSQY-----LEMDKTLSK 311
E L+ Q ++ + L E + +K+K + Q E D+ SK
Sbjct: 574 ILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSK 633
Query: 312 KEE-------------EVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKL 358
+EE EV++LQ L E + A A L+ +++ ++ + L+E+ Q
Sbjct: 634 EEELKDIQNMNFLLKAEVQKLQALANE-QAAAAHELEKMQQSVYVKDDKIRLLEEQLQHE 692
Query: 359 EKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQ----- 413
+EE + L + + L ++V+ LQ + + K++ ++Q ++ ++ KLK
Sbjct: 693 ISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDV-VEQMEKCIQEKDEKLKTVEELL 751
Query: 414 -----QVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNP 468
QVA EE+ + E + L +++ D K ++ + S EE L
Sbjct: 752 ETGLIQVATKEEELNAIRTENSSLTKEVQ---------DLKAKQNDQVSFASLVEE-LKK 801
Query: 469 ADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKE-SEKVSDIMLQKLKSLHLKKK 527
++ ++ S L A ++ + + + + K E++ ++ L+K + L + K
Sbjct: 802 VIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSK 861
Query: 528 TLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISH 587
++++ LL K ++ +++ + ++E ++ LA +
Sbjct: 862 ----------------VQELQNLLKGKEEQMNTM-----------KAVLEEKEKDLANTG 894
Query: 588 SQIAHLEERNKHLEDLIRKPREKARKPRSKS---------LENHPKSMTMMPALFKENRN 638
+ L+E N+ L+ +++ + K S + L+ + + A+ KE +
Sbjct: 895 KWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERES 954
Query: 639 DL 640
DL
Sbjct: 955 DL 956
Score = 53.9 bits (128), Expect = 4e-07
Identities = 65/300 (21%), Positives = 139/300 (46%), Gaps = 59/300 (19%)
Query: 169 LNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKIT--KQQVFIDVINKLKENVE 226
L+ + ++H +K R Q+++ L ++ +K+L K++ + + ++ ++ +
Sbjct: 1015 LDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAK 1074
Query: 227 ELI-----EDKYKII---LEKNDTKKTLQNLE-----EVLANTQKHLQESRNDKEMLQLQ 273
E + ++ K++ L++ D TL LE VLA T+ LQ+ + E + +
Sbjct: 1075 ECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENK 1134
Query: 274 FKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASA 333
+K ++ + +K++ Q M + + E+E+ERL+ K++E
Sbjct: 1135 WK--------------VKVDESHKTIKQ---MQSSFTSSEQELERLRSENKDIEN----- 1172
Query: 334 LDLLKREKEAQEQEFLSLQEEFQKLEKEN---LEERQKLKSRLEKLLTQVRNLQFMSENE 390
L+RE+E L+ E +K E E + E ++LK++L + LT++R +NE
Sbjct: 1173 ---LRRERE-------HLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRT----EQNE 1218
Query: 391 RTKNI----KLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITK 446
R K K QQ + ++++ K E + P+ E+++ K+ + L +T+
Sbjct: 1219 RQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSE-KETMSVSLNQTVTQ 1277
Score = 44.3 bits (103), Expect = 4e-04
Identities = 88/445 (19%), Positives = 175/445 (39%), Gaps = 79/445 (17%)
Query: 225 VEELIEDKYKIILE--KNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYV 282
V +L+++K +I + K +K L L L K L + D + + K+
Sbjct: 304 VVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQ------ 357
Query: 283 CLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKE 342
L + MTE ++ N +++ + TL K+ ++ + +
Sbjct: 358 -LTQEMMTEKERSNVVITRMKDRIGTLEKEH---------------------NVFQNKIH 395
Query: 343 AQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNI-KLQQQI 401
QE +Q +FQ++ ++ E LK L V N E++++ + KL+Q
Sbjct: 396 VSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDY 455
Query: 402 NEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEV------LKSDITKDT------- 448
+ NE + ++ + E Q + QLK QL+E ++S I K T
Sbjct: 456 ARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQ 515
Query: 449 --------------KTTHSNL---LPDCSPCEERLNPADIKRASQLASKMHSLLALMVGL 491
++ HS L L E+RL ++ + +K SL + +
Sbjct: 516 QDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQL-MESEQKRVNKEESLQMQVQDI 574
Query: 492 LTCQDIINSDAEHFKE-----------SEKVSDIMLQKLKSLHLKKKTL--DKEVIDCDS 538
L + + + + F +E++ ++ +K K + + +L +++ +
Sbjct: 575 LEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKE 634
Query: 539 DEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEI---IECADQRLAISHSQIAHLEE 595
+E K I+++ LL A++ K +L E E++ + D ++ + Q+ H E
Sbjct: 635 EELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQH-EI 693
Query: 596 RNKHLEDLIRKPREKARKPRSKSLE 620
NK E I + KA K + L+
Sbjct: 694 SNKMEEFKILNDQNKALKSEVQKLQ 718
Score = 30.8 bits (68), Expect = 4.0
Identities = 30/181 (16%), Positives = 76/181 (41%), Gaps = 17/181 (9%)
Query: 197 LEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANT 256
L+K + ++ + K +V +D +K + ++ + + K ++NL +
Sbjct: 1121 LQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHL 1180
Query: 257 QKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEV 316
+ L+++ ++ + +++KA + TE ++ K L K ++ +
Sbjct: 1181 EMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGD-------LHKAQQSL 1233
Query: 317 ERLQ-QLKKELEKATASALDLLKREKEAQEQEFLS---------LQEEFQKLEKENLEER 366
E +Q ++ K T + E E+ E+E +S LQ+ Q + ++ +E+
Sbjct: 1234 ELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEK 1293
Query: 367 Q 367
+
Sbjct: 1294 E 1294
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 73.6 bits (179), Expect = 5e-13
Identities = 63/282 (22%), Positives = 142/282 (50%), Gaps = 27/282 (9%)
Query: 174 QKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEEL----- 228
++LK N K + ++Q ++ ++ VKEL+ K+ + ++ + +L+ + L
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ-QQLQAEADHLGKELQ 263
Query: 229 -IEDKYKIILEKNDTKKTL-QNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCL-- 284
+ K + +E+N+ L Q EE + ++ +QE +E +Q Q +KI+ +
Sbjct: 264 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQER---EEKIQEQEEKIREQEEKMRR 320
Query: 285 QERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQ 344
QE M E ++K + ++ + +KEE++ L++ E EK + ++E++ Q
Sbjct: 321 QEEMMWEKEEKMR------RQEEMMWEKEEKIRELEEKMHEQEK-------IREQEEKRQ 367
Query: 345 EQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEV 404
E+E + QE+ Q+ E + + +K++ + EK+ Q +Q E + K+ +Q E+
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 405 KNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITK 446
+ + K+++Q + EQ + + ++++Q EE+++ K
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQ-EEMMQEQEEK 468
Score = 71.2 bits (173), Expect = 3e-12
Identities = 62/296 (20%), Positives = 150/296 (50%), Gaps = 10/296 (3%)
Query: 156 SAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFI 215
SA+ V+E+ N + Q+ + +QE +IQE + E++++E + K+ +Q+ +
Sbjct: 266 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMM 325
Query: 216 DVINKLKENVEELI---EDKYKIILEKNDTKKTLQNLEEVLANTQK-HLQESRNDKEM-L 270
+ EE++ E+K + + EK ++ ++ EE +K QE R ++E +
Sbjct: 326 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 385
Query: 271 QLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKAT 330
Q +KI+ ++E+ +Q+ K Q +K ++EE E+ ++++++ EK
Sbjct: 386 WRQEEKIREQEEKIREQEEMMQEQEEKMGEQE---EKMWEQEEEMQEQEEKMRRQEEKIR 442
Query: 331 ASALDLLKREKEAQEQEFLSLQEEFQKLEKEN--LEERQKLKSRLEKLLTQVRNLQFMSE 388
+ ++E++ +EQE + ++E + E+E E+ K++ + EK+ Q ++ +
Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK 502
Query: 389 NERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDI 444
R + K+++Q ++ + K+ +Q + EQ + + +++ Q E++ + ++
Sbjct: 503 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV 558
Score = 70.5 bits (171), Expect = 5e-12
Identities = 59/269 (21%), Positives = 136/269 (50%), Gaps = 24/269 (8%)
Query: 158 ESLQPVQEDMALNEVLQKLKHTNRKQE-----VRIQELQCSNLYLEKRVKELQMKITKQQ 212
E LQ V+ + + E+ +K RK E + Q+LQ +L K ++ + K+ Q
Sbjct: 216 EKLQLVESEKS--EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 273
Query: 213 VFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQL 272
++ N+L + EE + + + I E+ ++ +Q EE + + ++ R +EM+
Sbjct: 274 EENELWNRLNQQQEEKMWRQEEKIQER---EEKIQEQEEKIREQE---EKMRRQEEMMWE 327
Query: 273 QFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATAS 332
+ +K++ QE M E ++K + + + + + + ++EE+ + +++ +E EK
Sbjct: 328 KEEKMRR-----QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI-REQEKRQEQ 381
Query: 333 ALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERT 392
+ ++E++ +EQE E+ ++ E+ E+ +K+ + EK+ Q +Q E R
Sbjct: 382 EAKMWRQEEKIREQE-----EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436
Query: 393 KNIKLQQQINEVKNENAKLKQQVARSEEQ 421
+ K+++Q +++ + K+++Q +EQ
Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Score = 68.9 bits (167), Expect = 1e-11
Identities = 62/289 (21%), Positives = 144/289 (49%), Gaps = 22/289 (7%)
Query: 139 WRSEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLE 198
WR E + E EQ + + ++ E++ + + R+QE + E E
Sbjct: 291 WRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK-------E 343
Query: 199 KRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQK 258
++++EL+ K+ +Q+ + K +E EE I ++ K + + + + EE + ++
Sbjct: 344 EKIRELEEKMHEQEKIREQEEKRQE--EEKIREQEK----RQEQEAKMWRQEEKIREQEE 397
Query: 259 HLQESRNDKEMLQLQFKKI--KANYVCLQERYMTEMQQKNKSVSQYL-EMDKTLSKKEEE 315
++E +EM+Q Q +K+ + + QE M E ++K + + + E +K + ++EE+
Sbjct: 398 KIREQ---EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK 454
Query: 316 V-ERLQQLKKELEKATASALDLLKREKEAQEQE--FLSLQEEFQKLEKENLEERQKLKSR 372
+ E+ + ++++ EK + ++E + QEQE +E+ ++ EK+ E+ +K++ +
Sbjct: 455 IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 514
Query: 373 LEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQ 421
E + Q + E + K+Q+Q +++ + K+++Q R +Q
Sbjct: 515 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQ 563
Score = 58.5 bits (140), Expect = 2e-08
Identities = 89/485 (18%), Positives = 194/485 (40%), Gaps = 74/485 (15%)
Query: 148 CEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMK 207
C P+ EQ A Q AL L+ T R + ELQ + Y + VK+L+ +
Sbjct: 92 CHSPEDEQKASH----QHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGE 147
Query: 208 ITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDK 267
D+I++L D +K + ++ L + ++++E ++
Sbjct: 148 AR------DLISRL--------HDSWKFA---GELEQALSAVATQKKKADRYIEELTKER 190
Query: 268 EMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELE 327
+ L L+ L +T+ + K K+ ++ S+K E +++LK++LE
Sbjct: 191 DALSLE----------LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 240
Query: 328 KA--------TASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQ 379
+A + D L +E ++ + + EE + + N ++ +K+ + EK+ +
Sbjct: 241 RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQER 300
Query: 380 VRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEV 439
+Q E R + K+++Q + + K+++Q EE + + + +L++++ E
Sbjct: 301 EEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ----EEMMWEKEEKIRELEEKMHEQ 356
Query: 440 LKSDITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIIN 499
K ++ + EE++ + KR Q A ++ I
Sbjct: 357 EKIREQEEKRQE-----------EEKIREQE-KRQEQEAKMWRQ-----------EEKIR 393
Query: 500 SDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYH 559
E +E E++ +K+ K ++E+ E K R K+ +
Sbjct: 394 EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM---QEQEEKMRRQ-----EEKIREQE 445
Query: 560 SLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKPREKARKPRSKSL 619
E + + EE+++ ++++ ++ E + + E+ +R+ EK R+ K
Sbjct: 446 KKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIR 505
Query: 620 ENHPK 624
E K
Sbjct: 506 EQEEK 510
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 73.2 bits (178), Expect = 7e-13
Identities = 98/513 (19%), Positives = 218/513 (42%), Gaps = 54/513 (10%)
Query: 169 LNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEEL 228
L LQ +H + +E Q + L++ + + ++ + + + + EEL
Sbjct: 1333 LAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYET--DAIQRTEEL 1390
Query: 229 IEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQ--- 285
E K K+ D ++ ++ + A+ +K Q +N+ E L + ++ A + L
Sbjct: 1391 EEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQ 1450
Query: 286 ---ERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLK-KELEKATASALDLLKREK 341
++ + E +QK + LE S+KE + K K + + L+ LKRE
Sbjct: 1451 RNFDKVLAEWKQKYEETQAELEA----SQKESRSLSTELFKVKNAYEESLDHLETLKREN 1506
Query: 342 EAQEQEFLSLQEEFQKLEKENLEERQKLKSRLE----KLLTQVRNLQFMSENERTKNIKL 397
+ +QE L E+ + K ++ E +K+K +L+ +L T + + E+E K +++
Sbjct: 1507 KNLQQEISDLTEQIAEGGK-HIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRI 1565
Query: 398 QQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDI--TKDTKTTHSNL 455
Q ++N+VK+E + +++A +E+ K ++ + ++ L ++I D +
Sbjct: 1566 QLELNQVKSE---IDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKM 1622
Query: 456 LPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSD---AEHFKESEKVS 512
D + E +LN A+ + A L + ++ L L D I E E+ +
Sbjct: 1623 EGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRA 1682
Query: 513 DIMLQKLKSLHLK-------KKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEEL 565
++M +++ L +K ++E++D S+ + + T L ++ L ++
Sbjct: 1683 NLMQAEVEELRASLERTERGRKMAEQELLDA-SERVQLLHTQNTSL---INTKKKLETDI 1738
Query: 566 DFLVTSYEEIIECA-----------------DQRLAISHSQIAHLEERNKHLEDLIRKPR 608
+ E+I++ A + L AHLE K++E ++ +
Sbjct: 1739 SQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1798
Query: 609 EKARKPRSKSLENHPKSMTMMPALFKENRNDLD 641
+ + +L+ K + + A +E ++++
Sbjct: 1799 LRLDEAEQLALKGGKKQIQKLEARVRELESEVE 1831
Score = 70.5 bits (171), Expect = 5e-12
Identities = 107/566 (18%), Positives = 244/566 (43%), Gaps = 75/566 (13%)
Query: 99 KEIQNYGEIPEMSVSYEKEVTAEGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAE 158
+ N P M + ++ + + E + ++ + E + + + E+
Sbjct: 823 RAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMV 882
Query: 159 SLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKI---------- 208
+L + D+ L +Q E R +L + + LE ++KE+ +
Sbjct: 883 TLMQEKNDLQLQ--VQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAEL 940
Query: 209 -TKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDK 267
K++ D ++LK+++++L K+ EK+ T+ ++NL E +A + + + +K
Sbjct: 941 TAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEK 1000
Query: 268 EMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELE 327
+ LQ ++ + ++Q + V+ + K +K E++V+ L+ E E
Sbjct: 1001 KALQE-----------AHQQTLDDLQMEEDKVN---TLTKAKTKLEQQVDDLEG-SLEQE 1045
Query: 328 KATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMS 387
K L+ KR+ E L L +E ++ EN ++Q+L +L+K ++ NLQ
Sbjct: 1046 KKLCMDLERAKRKLEGD----LKLAQE-STMDTEN--DKQQLNEKLKKKEFEMSNLQGKI 1098
Query: 388 ENERTKNIKLQQQINEVKNENAKLKQQV-------ARSEEQNYVPKFETAQLKDQLEE-- 438
E+E+ I+LQ++I E++ +L++++ A++E+Q E ++ ++LEE
Sbjct: 1099 EDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1158
Query: 439 -VLKSDITKDTK-----------TTHSNLLPDCSPCEERLNPAD-----------IKRAS 475
+ I + K S L + + R AD ++R
Sbjct: 1159 GATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVK 1218
Query: 476 QLASKMHSLLALMVG-LLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVI 534
Q K S L + + L + + ++ +F++ + + L ++K+ +++ L E+
Sbjct: 1219 QKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINEL- 1277
Query: 535 DCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRL---AISHSQIA 591
S + + +LD+ ++ +L ++ + IE ++L + S +A
Sbjct: 1278 ---SAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLA 1334
Query: 592 HLEERNKHLEDLIRKPREKARKPRSK 617
H + +H DL+R+ E+ ++ +++
Sbjct: 1335 HALQSARHDCDLLREQYEEEQEAKAE 1360
Score = 65.9 bits (159), Expect = 1e-10
Identities = 117/523 (22%), Positives = 212/523 (40%), Gaps = 95/523 (18%)
Query: 164 QEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKE 223
+E AL E Q+ + +E ++ L + LE++V +L+ + +++ + + K
Sbjct: 998 KEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKR 1057
Query: 224 NVEELIEDKYKIILEKN-DTKKTLQNLEEVL-------ANTQKHLQESRNDKEMLQLQFK 275
+E K+ E DT+ Q L E L +N Q +++ + LQ + K
Sbjct: 1058 K----LEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIK 1113
Query: 276 KIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVE------------------ 317
+++A L+E E + K+ Q ++ + L + E +E
Sbjct: 1114 ELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1173
Query: 318 RLQQLKKELEKAT----ASALDLLKREKEAQE---QEFLSLQEEFQKLEKE--------- 361
Q+++++LE++T A+A L K+ ++ ++ SLQ QKLEKE
Sbjct: 1174 EFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEIN 1233
Query: 362 ----NLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVAR 417
N+E K K+ EK+ R L+ +TK + Q+ INE+ + A+L +
Sbjct: 1234 DLASNMETVSKAKANFEKM---CRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGE 1290
Query: 418 SEEQNYVPKFETAQLK-------DQLEEVLKSDITKDT--KTTHSNLLP----DCSPCEE 464
Q +QL Q+EE LK + ++T K+T ++ L DC E
Sbjct: 1291 FSRQLDEKDAMVSQLSRGKQAFTQQIEE-LKRQLEEETKAKSTLAHALQSARHDCDLLRE 1349
Query: 465 RLNPADIKRA--SQLASKMHSLLALMVGLLTCQDIINSD---------AEHFKESEKVSD 513
+ +A + SK +S +A I ++ A+ +++E+ +
Sbjct: 1350 QYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVE 1409
Query: 514 IMLQKLKSLHLKKKTLDKEV----IDCDSDEA------KSIRDVPTLLGAKLDKYHSLNE 563
+ K SL K+ L EV ID + A K R+ +L KY
Sbjct: 1410 AVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQA 1469
Query: 564 ELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRK 606
EL+ S +E + + + ++ EE HLE L R+
Sbjct: 1470 ELE---ASQKESRSLSTELFKVKNA----YEESLDHLETLKRE 1505
Score = 65.9 bits (159), Expect = 1e-10
Identities = 63/292 (21%), Positives = 133/292 (45%), Gaps = 30/292 (10%)
Query: 169 LNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVI-------NKL 221
LNE+ +L H NR+ ++ L+ + L+ L I Q + + N +
Sbjct: 1626 LNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLM 1685
Query: 222 KENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRND-----KEMLQLQFKK 276
+ VEEL + LE+ + + + E + A+ + L ++N K+ L+ +
Sbjct: 1686 QAEVEEL-----RASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
Query: 277 IKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDL 336
I+ + + ++ K+++ M + L K+++ L+++KK +E+ DL
Sbjct: 1741 IQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVK---DL 1797
Query: 337 LKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSR----------LEKLLTQVRNLQFM 386
R EA++ +++ QKLE E +++S L K +V+ L +
Sbjct: 1798 QLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQ 1857
Query: 387 SENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEE 438
+E +R ++LQ +++++ + K+Q +EEQ+ V + +L+ +LEE
Sbjct: 1858 TEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEE 1909
Score = 57.0 bits (136), Expect = 5e-08
Identities = 61/296 (20%), Positives = 122/296 (41%), Gaps = 27/296 (9%)
Query: 169 LNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEEL 228
L + L ++K +Q+ I EL L E ++ ++ + +++ K+ +
Sbjct: 1256 LEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQ 1315
Query: 229 IEDKYKIILEKNDTKKTL----QNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCL 284
IE+ + + E+ K TL Q+ ++ +E + K LQ K +
Sbjct: 1316 IEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQW 1375
Query: 285 QERYMT-------EMQQKNKSVSQYLE---------------MDKTLSKKEEEVERLQQL 322
+ +Y T E+++ K ++Q L+ ++KT + + EVE L +
Sbjct: 1376 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLM-I 1434
Query: 323 KKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRN 382
E A ALD +R + E+ EE Q + + +E + L + L K+
Sbjct: 1435 DVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEE 1494
Query: 383 LQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEE 438
E + +N LQQ+I+++ + A+ + + E+ E ++L+ LEE
Sbjct: 1495 SLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEE 1550
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 72.8 bits (177), Expect = 9e-13
Identities = 131/640 (20%), Positives = 258/640 (40%), Gaps = 118/640 (18%)
Query: 63 EMLKFTEKSLAKS----IAKESALNPSQPPSFLCKT------AVPSKEIQNYGEIPEMSV 112
+ +K TE SLA +KE L Q +FL K A+ +++ E+ +M
Sbjct: 614 KQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQ 673
Query: 113 SY----------EKEVTAEGVERPEIVSTWSSAGISWRSEACRENC---EMPDWEQSAES 159
S E+++ E + E + + +SE + E P+ + +
Sbjct: 674 SVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQM 733
Query: 160 LQPVQEDMALNEVLQKLKHTNRKQ----EVRIQELQCSNLYLEKRVKELQMKITKQQVFI 215
+ +QE + +++L T Q E + ++ N L K V++L+ K Q F
Sbjct: 734 EKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFA 793
Query: 216 DVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEV----LANTQKHLQESRNDKEMLQ 271
++ +LK K+I EK+ K+++ L E +AN +K +Q+ + + + L+
Sbjct: 794 SLVEELK-----------KVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALK 842
Query: 272 LQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATA 331
+ ++ E Q+ S+ E+ L KEE++ ++ + +E EK A
Sbjct: 843 EEIGNVQL-----------EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLA 891
Query: 332 SALDLLKREKEAQEQEFLSLQEEFQKLEKENLEER------QKLKSRLEKLLTQVRNLQF 385
+ L+ +E E SL+ Q++ + NL+E ++L+ L++ +++ L+
Sbjct: 892 NTGKWLQDLQEENE----SLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEA 947
Query: 386 MSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDIT 445
M + + Q + +V++EN K Q+ + ++QNY + A EE+LK +
Sbjct: 948 MLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNY----QQASSFPPHEELLK--VI 1001
Query: 446 KDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIIN-SDAEH 504
+ + S L + ++ + K ++ AL QD +N + E
Sbjct: 1002 SEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKER 1061
Query: 505 FKESEKVSDIMLQKLKSLHLKKKT------------LDKEVIDC-----DSDEAKSIR-- 545
++ E V + LK L K +K+ +C S+E K +
Sbjct: 1062 QQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHK 1121
Query: 546 -----DVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAI--------------- 585
++ TLL + +KY S+ E + ++ + +E + + +
Sbjct: 1122 LKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSS 1181
Query: 586 ---SHSQIAHLEERNKHLEDLIRKPR------EKARKPRS 616
S ++ L NK +E+L R+ EKA RS
Sbjct: 1182 FTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERS 1221
Score = 64.3 bits (155), Expect = 3e-10
Identities = 105/535 (19%), Positives = 241/535 (45%), Gaps = 69/535 (12%)
Query: 154 EQSAESLQPVQEDMA--LNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQ 211
+QSAE L +++D A +NE+ +K +++EV+ + + + L+ +++E + + +
Sbjct: 443 KQSAE-LNKLRQDYARLVNELTEKTGKL-QQEEVQKKNAEQAATQLKVQLQEAERRWEEV 500
Query: 212 QVFIDVINKLKENVEELIEDKY--------KIILEKNDTKKTLQNLEEVLANTQKHLQES 263
Q +I E ++ ++ K+ + + DT + Q LE+ L + Q+
Sbjct: 501 QSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKR 560
Query: 264 RNDKEMLQLQFKKIKANYVCLQ---ERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQ 320
N +E LQ+Q + I L+ +++ +++ + + E+ K +++K++++++ +
Sbjct: 561 VNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTE 620
Query: 321 -QLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKL------------EKENLEERQ 367
L E ++ T+ +L K+ Q FL L+ E QKL E E +++
Sbjct: 621 DSLASERDRLTSKEEEL----KDIQNMNFL-LKAEVQKLQALANEQAAAAHELEKMQQSV 675
Query: 368 KLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKF 427
+K +LL + LQ N+ + L Q +K+E KL+ V+ ++ V +
Sbjct: 676 YVKDDKIRLLEE--QLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQM 733
Query: 428 ETA-QLKDQ----LEEVLKSDITK-DTKTTHSNLLPDCSPCEERLNPADIKRASQLASKM 481
E Q KD+ +EE+L++ + + TK N + N + K L +K
Sbjct: 734 EKCIQEKDEKLKTVEELLETGLIQVATKEEELNAI-------RTENSSLTKEVQDLKAKQ 786
Query: 482 HSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQK-------LKSLHLKKKTLDKEVI 534
+ ++ + + +I+ K E++ + L K ++ L + K L +E+
Sbjct: 787 NDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIG 846
Query: 535 DCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLE 594
+ ++A+ + + +K+ + +L + + + + + ++E ++ LA + + L+
Sbjct: 847 NVQLEKAQQLS-----ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 901
Query: 595 ERNKHLEDLIRKPREKARKPRSKS---------LENHPKSMTMMPALFKENRNDL 640
E N+ L+ +++ + K S + L+ + + A+ KE +DL
Sbjct: 902 EENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDL 956
Score = 37.4 bits (85), Expect = 0.043
Identities = 40/207 (19%), Positives = 93/207 (44%), Gaps = 14/207 (6%)
Query: 140 RSEACRENCEMPDWEQSAESLQPVQEDMALNEV-LQKLKHTNRKQEVRIQELQCSNLYLE 198
RS EN ++S ++++ +Q +E L++L+ N+ I+ L+ +LE
Sbjct: 1155 RSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKD----IENLRREREHLE 1210
Query: 199 KRVKELQMKITKQQVFIDVINKLKENVEEL---IEDKYKIILEKNDTKKTLQNLEEVLAN 255
+++ +M ++ ++ + +LK+ + EL ++D Y + +N+ L L+ L
Sbjct: 1211 MELEKAEM---ERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNE---ELNLLKAQLNE 1264
Query: 256 TQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEE 315
T L+ +N+++ + K + + +Q + + + + + S+KE
Sbjct: 1265 TLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETM 1324
Query: 316 VERLQQLKKELEKATASALDLLKREKE 342
L Q +L++ + L +EKE
Sbjct: 1325 SVSLNQTVTQLQQLLQAVNQQLTKEKE 1351
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 72.8 bits (177), Expect = 9e-13
Identities = 131/640 (20%), Positives = 258/640 (40%), Gaps = 118/640 (18%)
Query: 63 EMLKFTEKSLAKS----IAKESALNPSQPPSFLCKT------AVPSKEIQNYGEIPEMSV 112
+ +K TE SLA +KE L Q +FL K A+ +++ E+ +M
Sbjct: 614 KQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQ 673
Query: 113 SY----------EKEVTAEGVERPEIVSTWSSAGISWRSEACRENC---EMPDWEQSAES 159
S E+++ E + E + + +SE + E P+ + +
Sbjct: 674 SVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQM 733
Query: 160 LQPVQEDMALNEVLQKLKHTNRKQ----EVRIQELQCSNLYLEKRVKELQMKITKQQVFI 215
+ +QE + +++L T Q E + ++ N L K V++L+ K Q F
Sbjct: 734 EKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFA 793
Query: 216 DVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEV----LANTQKHLQESRNDKEMLQ 271
++ +LK K+I EK+ K+++ L E +AN +K +Q+ + + + L+
Sbjct: 794 SLVEELK-----------KVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALK 842
Query: 272 LQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATA 331
+ ++ E Q+ S+ E+ L KEE++ ++ + +E EK A
Sbjct: 843 EEIGNVQL-----------EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLA 891
Query: 332 SALDLLKREKEAQEQEFLSLQEEFQKLEKENLEER------QKLKSRLEKLLTQVRNLQF 385
+ L+ +E E SL+ Q++ + NL+E ++L+ L++ +++ L+
Sbjct: 892 NTGKWLQDLQEENE----SLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEA 947
Query: 386 MSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDIT 445
M + + Q + +V++EN K Q+ + ++QNY + A EE+LK +
Sbjct: 948 MLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNY----QQASSFPPHEELLK--VI 1001
Query: 446 KDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIIN-SDAEH 504
+ + S L + ++ + K ++ AL QD +N + E
Sbjct: 1002 SEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKER 1061
Query: 505 FKESEKVSDIMLQKLKSLHLKKKT------------LDKEVIDC-----DSDEAKSIR-- 545
++ E V + LK L K +K+ +C S+E K +
Sbjct: 1062 QQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHK 1121
Query: 546 -----DVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAI--------------- 585
++ TLL + +KY S+ E + ++ + +E + + +
Sbjct: 1122 LKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSS 1181
Query: 586 ---SHSQIAHLEERNKHLEDLIRKPR------EKARKPRS 616
S ++ L NK +E+L R+ EKA RS
Sbjct: 1182 FTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERS 1221
Score = 64.3 bits (155), Expect = 3e-10
Identities = 105/535 (19%), Positives = 241/535 (45%), Gaps = 69/535 (12%)
Query: 154 EQSAESLQPVQEDMA--LNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQ 211
+QSAE L +++D A +NE+ +K +++EV+ + + + L+ +++E + + +
Sbjct: 443 KQSAE-LNKLRQDYARLVNELTEKTGKL-QQEEVQKKNAEQAATQLKVQLQEAERRWEEV 500
Query: 212 QVFIDVINKLKENVEELIEDKY--------KIILEKNDTKKTLQNLEEVLANTQKHLQES 263
Q +I E ++ ++ K+ + + DT + Q LE+ L + Q+
Sbjct: 501 QSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKR 560
Query: 264 RNDKEMLQLQFKKIKANYVCLQ---ERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQ 320
N +E LQ+Q + I L+ +++ +++ + + E+ K +++K++++++ +
Sbjct: 561 VNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTE 620
Query: 321 -QLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKL------------EKENLEERQ 367
L E ++ T+ +L K+ Q FL L+ E QKL E E +++
Sbjct: 621 DSLASERDRLTSKEEEL----KDIQNMNFL-LKAEVQKLQALANEQAAAAHELEKMQQSV 675
Query: 368 KLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKF 427
+K +LL + LQ N+ + L Q +K+E KL+ V+ ++ V +
Sbjct: 676 YVKDDKIRLLEE--QLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQM 733
Query: 428 ETA-QLKDQ----LEEVLKSDITK-DTKTTHSNLLPDCSPCEERLNPADIKRASQLASKM 481
E Q KD+ +EE+L++ + + TK N + N + K L +K
Sbjct: 734 EKCIQEKDEKLKTVEELLETGLIQVATKEEELNAI-------RTENSSLTKEVQDLKAKQ 786
Query: 482 HSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQK-------LKSLHLKKKTLDKEVI 534
+ ++ + + +I+ K E++ + L K ++ L + K L +E+
Sbjct: 787 NDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIG 846
Query: 535 DCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHLE 594
+ ++A+ + + +K+ + +L + + + + + ++E ++ LA + + L+
Sbjct: 847 NVQLEKAQQLS-----ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 901
Query: 595 ERNKHLEDLIRKPREKARKPRSKS---------LENHPKSMTMMPALFKENRNDL 640
E N+ L+ +++ + K S + L+ + + A+ KE +DL
Sbjct: 902 EENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDL 956
Score = 37.4 bits (85), Expect = 0.043
Identities = 40/207 (19%), Positives = 93/207 (44%), Gaps = 14/207 (6%)
Query: 140 RSEACRENCEMPDWEQSAESLQPVQEDMALNEV-LQKLKHTNRKQEVRIQELQCSNLYLE 198
RS EN ++S ++++ +Q +E L++L+ N+ I+ L+ +LE
Sbjct: 1155 RSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKD----IENLRREREHLE 1210
Query: 199 KRVKELQMKITKQQVFIDVINKLKENVEEL---IEDKYKIILEKNDTKKTLQNLEEVLAN 255
+++ +M ++ ++ + +LK+ + EL ++D Y + +N+ L L+ L
Sbjct: 1211 MELEKAEM---ERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNE---ELNLLKAQLNE 1264
Query: 256 TQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEE 315
T L+ +N+++ + K + + +Q + + + + + S+KE
Sbjct: 1265 TLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETM 1324
Query: 316 VERLQQLKKELEKATASALDLLKREKE 342
L Q +L++ + L +EKE
Sbjct: 1325 SVSLNQTVTQLQQLLQAVNQQLTKEKE 1351
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 72.8 bits (177), Expect = 9e-13
Identities = 64/285 (22%), Positives = 141/285 (49%), Gaps = 17/285 (5%)
Query: 155 QSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVF 214
+ A+ L P + L E + + + R+QE +I++ + E+R++E + K+ +Q+
Sbjct: 256 ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEK 315
Query: 215 IDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQF 274
+ K E+ + ++ K + E+ + ++ + ++E + ++ R +E + Q
Sbjct: 316 MWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 375
Query: 275 KKIKANYVCLQERYMTEMQQKNKSVSQYL-EMDKTLSKKEEEVERLQQLKKELEKATASA 333
+++ QE+ M E +QK + + + E D+ L +KEE + +++ +++EK
Sbjct: 376 ERLWE-----QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK----- 425
Query: 334 LDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQ-KLKSRLEKLLTQVRNLQFMSENERT 392
++ EK+ QEQE + +E + E+E + ER+ K++ E + Q +Q EN
Sbjct: 426 ---MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482
Query: 393 KNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLE 437
+ K QQ + + KL +Q E++ + + E +++DQ E
Sbjct: 483 QEEKEWQQ-QRLPEQKEKLWEQEKMQEQEEKIWEQE-EKIRDQEE 525
Score = 62.0 bits (149), Expect = 2e-09
Identities = 62/293 (21%), Positives = 134/293 (45%), Gaps = 28/293 (9%)
Query: 153 WEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQEL-----QCSNLYLEKRVKELQMK 207
WEQ + + Q+ E + + R++E R++E Q + EK+++E + K
Sbjct: 379 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438
Query: 208 ITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESR--N 265
Q+ + +++E +++ E++ + ++ +K +N+ E +K Q+ R
Sbjct: 439 TRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE---QEEKEWQQQRLPE 495
Query: 266 DKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKE 325
KE L Q K + QE + E ++K + + +K + ++E+ E+ Q+ ++
Sbjct: 496 QKEKLWEQEKMQE------QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549
Query: 326 LEKATASALDLL----KREKEAQEQEFLSLQEEFQKLEKENL--------EERQKLKSRL 373
EK + + EK+ QEQE + +E + E+E + EE + ++ +
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609
Query: 374 EKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPK 426
EK+ Q +Q E + K+Q+Q ++ + K+ +Q + EQ +P+
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE 662
Score = 61.6 bits (148), Expect = 2e-09
Identities = 67/316 (21%), Positives = 151/316 (47%), Gaps = 34/316 (10%)
Query: 140 RSEACRENCE-MPDWEQSAESLQPVQEDMALNEVLQKLKHTNRK--QEVRIQELQCSNLY 196
+ E RE E M + E+ E ++ ++E+ + E +K + K +E RI+E +
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE 461
Query: 197 LEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANT 256
E+ ++E + K+ KQ+ N ++ +E + + EK ++ +Q EE +
Sbjct: 462 EEETMREQEEKMQKQEE-----NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 516
Query: 257 QKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYL-EMDKTLSKKEEE 315
++ + R+ +EM + K + + QE M E ++K + Q + + ++ + KK +E
Sbjct: 517 EEKI---RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQE 573
Query: 316 VE----------RLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEE 365
E R ++ +E EK ++++ ++E +++ +QE+ +K+ E+
Sbjct: 574 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM----WEQ 629
Query: 366 RQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKN---ENAKLKQQVARSEEQN 422
+K++ + EK+ Q + E+ + + QQ++ E K E+ K+++Q E++
Sbjct: 630 EEKMQEQEEKMWEQEEKMW-----EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEE 684
Query: 423 YVPKFETAQLKDQLEE 438
+ + E + K Q +E
Sbjct: 685 KIWEQEKMEKKTQEQE 700
Score = 59.7 bits (143), Expect = 8e-09
Identities = 65/293 (22%), Positives = 137/293 (46%), Gaps = 26/293 (8%)
Query: 139 WRSEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLE 198
W E +E E WEQ + QE+M E + R+QE ++ E E
Sbjct: 501 WEQEKMQEQ-EEKIWEQEEKIRD--QEEMWGQEKKMWRQEKMREQEDQMWEQ-------E 550
Query: 199 KRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQK 258
+++++ + K+ Q+ ++ + +E E+K + + +K ++ EE++ ++
Sbjct: 551 EKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 610
Query: 259 HLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEM--DKTLSKKEEEV 316
+QE +E +Q Q +K+ +QE+ +Q+ K Q +M + L +++E++
Sbjct: 611 KMQEQ---EEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Query: 317 ---ERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRL 373
E++Q+ +K +++ + K EK+ QEQE + +E + E+ E +K++
Sbjct: 668 WEHEKMQEQEK-MQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Query: 374 EKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPK 426
E + Q +Q E K+Q+Q E+ + K+ +Q + EQ +P+
Sbjct: 727 EMMREQEEKMQEQEE-------KMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE 772
Score = 55.1 bits (131), Expect = 2e-07
Identities = 63/314 (20%), Positives = 144/314 (45%), Gaps = 25/314 (7%)
Query: 114 YEKEVTAEGVERPEIVSTWSSAGISWRSEACRENCEM--PDWEQSAESLQPVQEDMALNE 171
+++E E + + TW E RE + + E E + +QE E
Sbjct: 561 WDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ---EE 617
Query: 172 VLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENV----EE 227
+Q+ + +QE ++QE + E+++ E + K+ +QQ + KL E+ +E
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 677
Query: 228 LIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQER 287
++++ + I E+ +K Q E+ + QE ++E ++ + KK++ +E
Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWD-----QEKMREEESMREREKKMRE-----EEE 727
Query: 288 YMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQE 347
M E ++K + E ++ + ++EEE+ ++ E E+ L +++++ E E
Sbjct: 728 MMREQEEKMQ------EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 781
Query: 348 FLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNE 407
+ QE+ + E++ ++ +K++ + EK+ Q ++ E + K+ Q ++ +
Sbjct: 782 KMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQ 841
Query: 408 NAKLKQQVARSEEQ 421
K+ Q + EE+
Sbjct: 842 EEKMWGQEEKMEEK 855
Score = 54.3 bits (129), Expect = 3e-07
Identities = 63/332 (18%), Positives = 156/332 (46%), Gaps = 31/332 (9%)
Query: 142 EACRENCEMPDWEQSA-ESLQPVQEDMALNEVLQKLKH---TNRKQEVRIQELQCSNLYL 197
E RE +M + E+ + + +QE+ + E +K++ T R+QE ++Q+ Q N++
Sbjct: 424 EKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQK-QEENMWE 482
Query: 198 EKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKN----DTKKTLQNLEEVL 253
++ + Q ++ +Q+ + K++E E++ E + KI ++ + K Q
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 254 ANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKE 313
+ +E D+E ++ QE+ + ++K + + E +K + ++E
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 602
Query: 314 EEV--------ERLQQLKKELEKATASALDLLKREKEAQEQ------------EFLSLQE 353
E + E+ ++++++ EK + ++E++ EQ E L E
Sbjct: 603 EMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE 662
Query: 354 EFQKL-EKENLEERQKLKSRLEKLLTQVRNLQFMSENE-RTKNIKLQQQINEVKNENAKL 411
+ +KL E E ++E++K++ + EK+ Q + + E E +T + + ++ ++ K+
Sbjct: 663 QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKM 722
Query: 412 KQQVARSEEQNYVPKFETAQLKDQLEEVLKSD 443
+++ EQ + + ++++Q EE+ + +
Sbjct: 723 REEEEMMREQEEKMQEQEEKMQEQEEEMWEQE 754
Score = 47.0 bits (110), Expect = 5e-05
Identities = 53/279 (18%), Positives = 125/279 (44%), Gaps = 34/279 (12%)
Query: 139 WRSEACRENCEMPDWEQSA---ESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNL 195
W E + E WEQ E + + E L E +KL + QE + Q +
Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKI 686
Query: 196 Y----LEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEE 251
+ +EK+ +E + K Q+ K++E EE + ++ K + E+ + ++ EE
Sbjct: 687 WEQEKMEKKTQEQEKKTWDQE-------KMRE--EESMREREKKMREEEEM---MREQEE 734
Query: 252 VLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSK 311
+ ++ +QE ++EM + + K + +++ + E ++K + E +K +
Sbjct: 735 KMQEQEEKMQEQ--EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQ 792
Query: 312 KEEEVERLQQLKKELEKATASALDLLKREKE---------AQEQEFLSLQEEF----QKL 358
+E+ ++ ++++ + EK + +E++ QE++ +E+ +K+
Sbjct: 793 EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKM 852
Query: 359 EKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKL 397
E++ + +K++ + EK+ Q ++ E R + K+
Sbjct: 853 EEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 46.2 bits (108), Expect = 9e-05
Identities = 41/186 (22%), Positives = 87/186 (46%), Gaps = 21/186 (11%)
Query: 258 KHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVE 317
++++E +++ L L+ L +T + K K+ E+ + L E E
Sbjct: 197 RYIEELTKERDALSLE----------LYRNTITNEELKKKNA----ELQEKLPLAESEKS 242
Query: 318 RLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLL 377
+Q KEL++ A LL + + +LQEE + E+E E+ +K++ + EK+
Sbjct: 243 EIQLNVKELKRKLERAKFLL------PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 296
Query: 378 TQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLE 437
Q L+ R + K+ +Q ++ + +L++Q EQ + + E Q+++Q E
Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQE-EQMQEQEE 355
Query: 438 EVLKSD 443
++ + +
Sbjct: 356 KMWEQE 361
Score = 40.8 bits (94), Expect = 0.004
Identities = 44/246 (17%), Positives = 113/246 (45%), Gaps = 10/246 (4%)
Query: 132 WSSAGISWRSEACRENCEMPDWEQSAESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQ 191
W + + E E+ +M + E+ E + + E + + Q+ + QE +++E +
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE-KMREEE 713
Query: 192 CSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEE 251
+K +E +M +++ + K++E EE+ E + K+ E+ + Q L E
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKM-WEQEEKMWEQQRLPE 772
Query: 252 VLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLE-MDKTLS 310
+H E ++E + Q +K++ QE M ++K + + + ++ +
Sbjct: 773 QKEKLWEH--EKMQEQEKIWEQEEKMRD-----QEEKMRGQEEKMRGQEEKMRGQEEKMW 825
Query: 311 KKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLK 370
+EE++ ++ E+ + ++ + + QE++ +E+ + E++ E+ +K++
Sbjct: 826 GQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Query: 371 SRLEKL 376
+ EK+
Sbjct: 886 GQEEKI 891
Score = 30.4 bits (67), Expect = 5.2
Identities = 24/108 (22%), Positives = 51/108 (47%), Gaps = 1/108 (0%)
Query: 315 EVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLK-SRL 373
E++R K ++ L +E++A E ++L+K+N E ++KL +
Sbjct: 180 ELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAES 239
Query: 374 EKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQ 421
EK Q+ + + ER K + Q Q N ++ E + ++++ E++
Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 287
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 72.8 bits (177), Expect = 9e-13
Identities = 77/320 (24%), Positives = 141/320 (44%), Gaps = 47/320 (14%)
Query: 158 ESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQ------ 211
+S + +E + E QK+K K E + +EL+ + L K +LQ+++ +
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 212 ---------QVFIDVINKLKENVE----------ELIEDKYKIILEKNDTKKTLQNLEEV 252
+ I + K+KE E EL K K+ E ++ KK + +LE
Sbjct: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
Query: 253 LANTQKHLQESRND-----KEMLQLQ--FKKIKANYVCLQERYMTEMQQKNKSVSQYLEM 305
LA +K + N +EM L K+ LQE + + + +
Sbjct: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026
Query: 306 DKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEE 365
K K E++V+ L+ LE+ +DL +R K E + QE +E E
Sbjct: 1027 TKAKIKLEQQVD---DLEGSLEQEKKLRMDL-ERAKRKLEGDLKLAQESIMDIENE---- 1078
Query: 366 RQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQV-------ARS 418
+Q+L +L+K ++ NLQ E+E+ I+LQ++I E++ +L++++ A++
Sbjct: 1079 KQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKA 1138
Query: 419 EEQNYVPKFETAQLKDQLEE 438
E+Q E ++ ++LEE
Sbjct: 1139 EKQRSDLSRELEEISERLEE 1158
Score = 62.8 bits (151), Expect = 1e-09
Identities = 61/293 (20%), Positives = 136/293 (46%), Gaps = 32/293 (10%)
Query: 169 LNEVLQKLKHTNRKQEVRIQE-------LQCSNLYLEKRVKELQMKITKQQVFIDV-INK 220
LNE+ +L H NR ++ L+ + ++L+ ++ Q + +Q ++ N
Sbjct: 1628 LNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRS-QEDLKEQLAMVERRANL 1686
Query: 221 LKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRND-----KEMLQLQFK 275
L+ +EEL + LE+ + + + E + A+ + L ++N K+ L+
Sbjct: 1687 LQAEIEEL-----RATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1741
Query: 276 KIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALD 335
+++ + + ++ K+++ M + L K+++ L+++KK +E+ D
Sbjct: 1742 QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVK---D 1798
Query: 336 LLKREKEAQEQEFLSLQEEFQKLEKE------NLEERQKLKSR----LEKLLTQVRNLQF 385
L R EA++ +++ QKLE +E QK + L K +V+ L +
Sbjct: 1799 LQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTY 1858
Query: 386 MSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEE 438
+E +R ++LQ +++++ + K+Q +EEQ+ + +L+ +LEE
Sbjct: 1859 QTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEE 1911
Score = 62.0 bits (149), Expect = 2e-09
Identities = 89/451 (19%), Positives = 193/451 (42%), Gaps = 33/451 (7%)
Query: 164 QEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKE 223
+E AL E Q+ + +E ++ L + + LE++V +L+ + +++ + + K
Sbjct: 1000 KEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKR 1059
Query: 224 NVEELIEDKYKIIL----EKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKA 279
+E ++ + I+ EK + L+ E ++N Q +++ + LQ + K+++A
Sbjct: 1060 KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQA 1119
Query: 280 NYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKR 339
L+E E + K+ Q ++ + L EE ERL+ E AT++ +++ K+
Sbjct: 1120 RIEELEEEIEAERASRAKAEKQRSDLSREL---EEISERLE----EAGGATSAQIEMNKK 1172
Query: 340 EKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQ 399
+ ++ L+E + E R+K + +L Q+ NLQ + + KL++
Sbjct: 1173 REAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ-------KLEK 1225
Query: 400 QINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDC 459
+ +E+K E L V + + L+DQL E+ K + L+ D
Sbjct: 1226 EKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSEL------KSKEEEQQRLINDL 1279
Query: 460 SPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKL 519
+ RL + + QL K + L G I +E K + + L
Sbjct: 1280 TAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHAL 1339
Query: 520 KS----LHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHS----LNEELDFLVTS 571
+S L ++ ++E + ++ +++ T + KY + EEL+
Sbjct: 1340 QSSRHDCDLLREQYEEEQ-ESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
Query: 572 YEEIIECADQRLAISHSQIAHLEERNKHLED 602
+ ++ A++ + +++ A LE+ + L++
Sbjct: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQN 1429
Score = 55.5 bits (132), Expect = 2e-07
Identities = 65/321 (20%), Positives = 132/321 (41%), Gaps = 32/321 (9%)
Query: 149 EMPDWEQSAESLQPVQEDM-----ALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKE 203
E+ D + E++ + ++ L + L +LK +Q+ I +L L+ E
Sbjct: 1233 EIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGE 1292
Query: 204 LQMKITKQQVFIDVINKLKE----NVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKH 259
++ +++ + +++ K+ +EEL + I KN LQ+ ++
Sbjct: 1293 FSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQ 1352
Query: 260 LQESRNDKEMLQLQFKKIKANYVCLQERYMT-------EMQQKNKSVSQYLE-------- 304
+E + K LQ K + +Y T E+++ K ++Q L+
Sbjct: 1353 YEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEA 1412
Query: 305 -------MDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQK 357
++KT + + EVE L L E A +ALD +R + E+ EE
Sbjct: 1413 VNAKCASLEKTKQRLQNEVEDLM-LDVERTNAACAALDKKQRNFDKILAEWKQKCEETHA 1471
Query: 358 LEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVAR 417
+ + +E + L + L K+ E + +N LQQ+I+++ + A+ +++
Sbjct: 1472 ELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE 1531
Query: 418 SEEQNYVPKFETAQLKDQLEE 438
E+ + E +L+ LEE
Sbjct: 1532 LEKIKKQVEQEKCELQAALEE 1552
Score = 54.7 bits (130), Expect = 3e-07
Identities = 118/576 (20%), Positives = 249/576 (43%), Gaps = 78/576 (13%)
Query: 106 EIPEMSVSYEKEVTAEGVERPEIVSTWSSAGISWRSEACRE-----NCEMPDWEQSAESL 160
E+ + YE + E E + ++ R +A E N + E++ + L
Sbjct: 1373 EVAQWRTKYETDAIQRTEELEE-----AKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRL 1427
Query: 161 QPVQEDMAL-----NEVLQKLKHTNRKQEVRIQELQ--CSNLYLEKRVKELQMKITKQQV 213
Q ED+ L N L R + + E + C + E + + + ++
Sbjct: 1428 QNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTEL 1487
Query: 214 FIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQ 273
F K+K EE ++ + E + ++ + +L E +A K + E K+ ++ +
Sbjct: 1488 F-----KIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE 1542
Query: 274 FKKIKANYVCLQERYMTEMQQKNKSVSQYLEM-------DKTLSKKEEEVERLQQLKKEL 326
+++A L+E + ++ K + LE+ D+ +++K+EE+++L++ +
Sbjct: 1543 KCELQA---ALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRI 1599
Query: 327 EKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFM 386
++ S LD R + + ++ + ++E + L ++ + + L RN Q +
Sbjct: 1600 VESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQ-LNHANRMAA---EALRNYRNTQGI 1655
Query: 387 SENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITK 446
++ Q +++ LK+Q+A E + + + E +L+ LE+ +S
Sbjct: 1656 LKD-------TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS---- 1704
Query: 447 DTKTTHSNLLPDCSPCEERL---NPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAE 503
K LL D S + L N + I +L + + + M +L Q+ N++ E
Sbjct: 1705 -RKIAEQELL-DASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDIL--QEARNAE-E 1759
Query: 504 HFKESEKVSDIMLQKLK-----SLHLK--KKTLDKEVIDCD--SDEAKSIRDVPTLLGAK 554
K++ + +M ++LK S HL+ KK +++ V D DEA+ + L G K
Sbjct: 1760 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQL----ALKGGK 1815
Query: 555 --LDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHL----EERNKH---LEDLIR 605
+ K + EL+ V S ++ A + L ++ L EE K+ L+DL+
Sbjct: 1816 KQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVD 1875
Query: 606 KPREKARKPRSKSLENHPKSMTMMPALFKENRNDLD 641
K + K + + ++ E +S T + A F++ +++L+
Sbjct: 1876 KLQAKVKSYKRQAEEAEEQSNTNL-AKFRKLQHELE 1910
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 72.8 bits (177), Expect = 9e-13
Identities = 77/320 (24%), Positives = 141/320 (44%), Gaps = 47/320 (14%)
Query: 158 ESLQPVQEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQ------ 211
+S + +E + E QK+K K E + +EL+ + L K +LQ+++ +
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 212 ---------QVFIDVINKLKENVE----------ELIEDKYKIILEKNDTKKTLQNLEEV 252
+ I + K+KE E EL K K+ E ++ KK + +LE
Sbjct: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
Query: 253 LANTQKHLQESRND-----KEMLQLQ--FKKIKANYVCLQERYMTEMQQKNKSVSQYLEM 305
LA +K + N +EM L K+ LQE + + + +
Sbjct: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026
Query: 306 DKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEE 365
K K E++V+ L+ LE+ +DL +R K E + QE +E E
Sbjct: 1027 TKAKIKLEQQVD---DLEGSLEQEKKLRMDL-ERAKRKLEGDLKLAQESIMDIENE---- 1078
Query: 366 RQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQV-------ARS 418
+Q+L +L+K ++ NLQ E+E+ I+LQ++I E++ +L++++ A++
Sbjct: 1079 KQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKA 1138
Query: 419 EEQNYVPKFETAQLKDQLEE 438
E+Q E ++ ++LEE
Sbjct: 1139 EKQRSDLSRELEEISERLEE 1158
Score = 62.8 bits (151), Expect = 1e-09
Identities = 61/293 (20%), Positives = 136/293 (46%), Gaps = 32/293 (10%)
Query: 169 LNEVLQKLKHTNRKQEVRIQE-------LQCSNLYLEKRVKELQMKITKQQVFIDV-INK 220
LNE+ +L H NR ++ L+ + ++L+ ++ Q + +Q ++ N
Sbjct: 1628 LNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRS-QEDLKEQLAMVERRANL 1686
Query: 221 LKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRND-----KEMLQLQFK 275
L+ +EEL + LE+ + + + E + A+ + L ++N K+ L+
Sbjct: 1687 LQAEIEEL-----RATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1741
Query: 276 KIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALD 335
+++ + + ++ K+++ M + L K+++ L+++KK +E+ D
Sbjct: 1742 QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVK---D 1798
Query: 336 LLKREKEAQEQEFLSLQEEFQKLEKE------NLEERQKLKSR----LEKLLTQVRNLQF 385
L R EA++ +++ QKLE +E QK + L K +V+ L +
Sbjct: 1799 LQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTY 1858
Query: 386 MSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEE 438
+E +R ++LQ +++++ + K+Q +EEQ+ + +L+ +LEE
Sbjct: 1859 QTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEE 1911
Score = 62.0 bits (149), Expect = 2e-09
Identities = 89/451 (19%), Positives = 193/451 (42%), Gaps = 33/451 (7%)
Query: 164 QEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKE 223
+E AL E Q+ + +E ++ L + + LE++V +L+ + +++ + + K
Sbjct: 1000 KEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKR 1059
Query: 224 NVEELIEDKYKIIL----EKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKA 279
+E ++ + I+ EK + L+ E ++N Q +++ + LQ + K+++A
Sbjct: 1060 KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQA 1119
Query: 280 NYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKR 339
L+E E + K+ Q ++ + L EE ERL+ E AT++ +++ K+
Sbjct: 1120 RIEELEEEIEAERASRAKAEKQRSDLSREL---EEISERLE----EAGGATSAQIEMNKK 1172
Query: 340 EKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQ 399
+ ++ L+E + E R+K + +L Q+ NLQ + + KL++
Sbjct: 1173 REAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ-------KLEK 1225
Query: 400 QINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDC 459
+ +E+K E L V + + L+DQL E+ K + L+ D
Sbjct: 1226 EKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSEL------KSKEEEQQRLINDL 1279
Query: 460 SPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKL 519
+ RL + + QL K + L G I +E K + + L
Sbjct: 1280 TAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHAL 1339
Query: 520 KS----LHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHS----LNEELDFLVTS 571
+S L ++ ++E + ++ +++ T + KY + EEL+
Sbjct: 1340 QSSRHDCDLLREQYEEEQ-ESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
Query: 572 YEEIIECADQRLAISHSQIAHLEERNKHLED 602
+ ++ A++ + +++ A LE+ + L++
Sbjct: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQN 1429
Score = 55.5 bits (132), Expect = 2e-07
Identities = 65/321 (20%), Positives = 132/321 (41%), Gaps = 32/321 (9%)
Query: 149 EMPDWEQSAESLQPVQEDM-----ALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKE 203
E+ D + E++ + ++ L + L +LK +Q+ I +L L+ E
Sbjct: 1233 EIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGE 1292
Query: 204 LQMKITKQQVFIDVINKLKE----NVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKH 259
++ +++ + +++ K+ +EEL + I KN LQ+ ++
Sbjct: 1293 FSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQ 1352
Query: 260 LQESRNDKEMLQLQFKKIKANYVCLQERYMT-------EMQQKNKSVSQYLE-------- 304
+E + K LQ K + +Y T E+++ K ++Q L+
Sbjct: 1353 YEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEA 1412
Query: 305 -------MDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQK 357
++KT + + EVE L L E A +ALD +R + E+ EE
Sbjct: 1413 VNAKCASLEKTKQRLQNEVEDLM-LDVERTNAACAALDKKQRNFDKILAEWKQKCEETHA 1471
Query: 358 LEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVAR 417
+ + +E + L + L K+ E + +N LQQ+I+++ + A+ +++
Sbjct: 1472 ELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE 1531
Query: 418 SEEQNYVPKFETAQLKDQLEE 438
E+ + E +L+ LEE
Sbjct: 1532 LEKIKKQVEQEKCELQAALEE 1552
Score = 54.7 bits (130), Expect = 3e-07
Identities = 118/576 (20%), Positives = 249/576 (43%), Gaps = 78/576 (13%)
Query: 106 EIPEMSVSYEKEVTAEGVERPEIVSTWSSAGISWRSEACRE-----NCEMPDWEQSAESL 160
E+ + YE + E E + ++ R +A E N + E++ + L
Sbjct: 1373 EVAQWRTKYETDAIQRTEELEE-----AKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRL 1427
Query: 161 QPVQEDMAL-----NEVLQKLKHTNRKQEVRIQELQ--CSNLYLEKRVKELQMKITKQQV 213
Q ED+ L N L R + + E + C + E + + + ++
Sbjct: 1428 QNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTEL 1487
Query: 214 FIDVINKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQ 273
F K+K EE ++ + E + ++ + +L E +A K + E K+ ++ +
Sbjct: 1488 F-----KIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE 1542
Query: 274 FKKIKANYVCLQERYMTEMQQKNKSVSQYLEM-------DKTLSKKEEEVERLQQLKKEL 326
+++A L+E + ++ K + LE+ D+ +++K+EE+++L++ +
Sbjct: 1543 KCELQA---ALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRI 1599
Query: 327 EKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFM 386
++ S LD R + + ++ + ++E + L ++ + + L RN Q +
Sbjct: 1600 VESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQ-LNHANRMAA---EALRNYRNTQGI 1655
Query: 387 SENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITK 446
++ Q +++ LK+Q+A E + + + E +L+ LE+ +S
Sbjct: 1656 LKD-------TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS---- 1704
Query: 447 DTKTTHSNLLPDCSPCEERL---NPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAE 503
K LL D S + L N + I +L + + + M +L Q+ N++ E
Sbjct: 1705 -RKIAEQELL-DASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDIL--QEARNAE-E 1759
Query: 504 HFKESEKVSDIMLQKLK-----SLHLK--KKTLDKEVIDCD--SDEAKSIRDVPTLLGAK 554
K++ + +M ++LK S HL+ KK +++ V D DEA+ + L G K
Sbjct: 1760 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQL----ALKGGK 1815
Query: 555 --LDKYHSLNEELDFLVTSYEEIIECADQRLAISHSQIAHL----EERNKH---LEDLIR 605
+ K + EL+ V S ++ A + L ++ L EE K+ L+DL+
Sbjct: 1816 KQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVD 1875
Query: 606 KPREKARKPRSKSLENHPKSMTMMPALFKENRNDLD 641
K + K + + ++ E +S T + A F++ +++L+
Sbjct: 1876 KLQAKVKSYKRQAEEAEEQSNTNL-AKFRKLQHELE 1910
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 72.0 bits (175), Expect = 2e-12
Identities = 116/522 (22%), Positives = 236/522 (45%), Gaps = 91/522 (17%)
Query: 164 QEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKE 223
+ED+ L E + +L+ +K ++ ++E N LE +++Q K Q++ LKE
Sbjct: 715 KEDVILKEHITQLE---KKLQLMVEEQDNLNKLLEN--EQVQKLFVKTQLY----GFLKE 765
Query: 224 NVEELIEDKYKIILEKNDTKKTLQNLEEVLA--NTQKHLQESRNDKEMLQLQFKKIKANY 281
E+ ED E+ D LQ + E LA N +K + D+++L+L+ K+IK
Sbjct: 766 MGSEVSEDS-----EEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELE-KEIK--- 816
Query: 282 VCLQERYMTEMQQKNKSVSQYLEMDKTLSKKE-----EEVERLQ----QLKKELEKATAS 332
CLQE + + ++ + Y E +K L +KE E E LQ ++K EK
Sbjct: 817 -CLQEESVVQCEELKSLLRDY-EQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLE 874
Query: 333 ALDLLKREKEAQE----QEFLSLQEEFQKLEKENLE---ERQKLKSRLEKL--------- 376
+LL + +E + E + +E+ E ENL+ E+++L+ R +L
Sbjct: 875 NQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAK 934
Query: 377 --------LTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFE 428
L+ V+ L+ EN + + +++IN++K K K+++ S ++ K E
Sbjct: 935 SPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEE 994
Query: 429 TAQLKDQLEEVLKS--DITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLA 486
L+ + +++ S D+ + ++ + NLL + E+L+ + +RA+ ++ L
Sbjct: 995 LESLRSEKDQLSASMRDLIQGAES-YKNLLLEYEKQSEQLD-VEKERANNFEHRIEDLTR 1052
Query: 487 LMVGLLTCQDIINSDAEHF-------KESEKVSDIML---QKLKSL---HLKKKTLDKEV 533
+ + INSD E + + K+ ++ + Q+ K++ L+ + L KE
Sbjct: 1053 QLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQ 1112
Query: 534 -IDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFL-------------VTSYEEIIECA 579
I + + ++ L + + +EL+ + + YE +++
Sbjct: 1113 KIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKEL 1172
Query: 580 DQRLAISHSQIAHLEERNKHLEDLIRKPREKARKPRSKSLEN 621
+Q+L +++I LE+ K I+K +++ + SL++
Sbjct: 1173 NQKLTNKNNKIEDLEQEIK-----IQKQKQETLQEEITSLQS 1209
Score = 71.6 bits (174), Expect = 2e-12
Identities = 102/516 (19%), Positives = 232/516 (44%), Gaps = 63/516 (12%)
Query: 164 QEDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKE 223
+E + E L+ L+ + +++L + + K L ++ KQ +DV +
Sbjct: 986 KETQTVKEELESLRSEKDQLSASMRDL----IQGAESYKNLLLEYEKQSEQLDVEKERAN 1041
Query: 224 NVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVC 283
N E IED + + +T+ + E L + LQ ++ ++L++Q +++
Sbjct: 1042 NFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQ---SNAKLLEVQILEVQRAKAM 1098
Query: 284 LQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEA 343
+ + E QK + + ++ T+++ EE +LQ+ KK+L+K T L+L+K K+A
Sbjct: 1099 VDKELEAEKLQKEQKIKEHAT---TVNELEELQVQLQKEKKQLQK-TMQELELVK--KDA 1152
Query: 344 QEQEFLSLQ-EEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQIN 402
Q+ ++++ ++++L KE ++ +++E L +++ + E + + LQ +
Sbjct: 1153 QQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQ 1212
Query: 403 EVKNENAKLKQQVARSEEQNYVPK-FET------AQLKDQLE------EVLK---SDITK 446
+ + +N K+KQ + +++++ K ET A LK +LE EV K ++IT
Sbjct: 1213 QYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITS 1272
Query: 447 DTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFK 506
+ H +L + L+ A +R + L + + A Q + S+ E +K
Sbjct: 1273 EKHKIHEHLKTSAEQHQRTLS-AYQQRVTALQEECRAAKAE-------QATVTSEFESYK 1324
Query: 507 ESEKVSDIMLQKLKSLHLKKKT----LDKEVIDCDSDEAK-SIRDVPTLLGAKLDKYHSL 561
+V +++ Q+ + +T ++E ++ D+ K ++D L + + +L
Sbjct: 1325 --VRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTL 1382
Query: 562 NEELDFLVTSYEEI-----------------IECADQRLAISHSQ-IAHLEERNKHLEDL 603
E D L+ + ++ I+ + + H+Q ++ L +N+ L +
Sbjct: 1383 QSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNS 1442
Query: 604 IRKPREKARKPRSKSLENHPKSMTMMPALFKENRND 639
R ++ K++E + ++ M A + +N+
Sbjct: 1443 FRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQLKNE 1478
Score = 63.9 bits (154), Expect = 4e-10
Identities = 114/506 (22%), Positives = 227/506 (44%), Gaps = 79/506 (15%)
Query: 149 EMPDWEQSAESLQPVQEDMALNEVLQKLKHT---NRKQEVRIQELQCSNLYLEKRVKELQ 205
EM ++ + E +E+ + E+ +K++ T N + E ++ EL LE+ +KE
Sbjct: 609 EMDNFHKKCE-----REERLILELGKKVEQTIQYNSELEQKVNELTGG---LEETLKEKD 660
Query: 206 M---KITKQQVFIDVINKLKE----NVEELIEDKYKIILEKNDTKKTLQ----NLEEVLA 254
K+ K V + V+++ KE V+ L E+ K+ EK + L+ E+V+
Sbjct: 661 QNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVIL 720
Query: 255 NTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEE 314
++H+ + ++ LQL ++ L+ + ++ K + EM +S+ E
Sbjct: 721 --KEHITQL---EKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSE 775
Query: 315 E---VERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKS 371
E V LQ + + L K +L + ++++ L L++E + L++E++ + ++LKS
Sbjct: 776 EKDVVNVLQAVGESLAKINEEKCNLAFQ----RDEKVLELEKEIKCLQEESVVQCEELKS 831
Query: 372 RL-----EKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPK 426
L EK+L + + SE E LQ + E+KN N K R E QN +
Sbjct: 832 LLRDYEQEKVLLRKELEEIQSEKEA-----LQSDLLEMKNANEK-----TRLENQNLL-- 879
Query: 427 FETAQLKDQLEEVLKSDITKDTK----TTHSNLLPDCSPCEERLNPADIKRASQLASKMH 482
Q+++ + KS+I + + H NL P E R A++ +K
Sbjct: 880 ---IQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSP 936
Query: 483 SL----LALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDS 538
S+ L+ + L + I N + E ++ EK++ I L +K+ K+ +D
Sbjct: 937 SVKNDPLSSVKELE--EKIENLEKECKEKEEKINKIKLVAVKA---------KKELDSSR 985
Query: 539 DEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEII---ECADQRLAISHSQIAHLEE 595
E +++++ L ++ D+ + +L SY+ ++ E ++L + + + E
Sbjct: 986 KETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEH 1045
Query: 596 RNKHLEDLIRKPREKARKPRSKSLEN 621
R +EDL R+ R + + + +N
Sbjct: 1046 R---IEDLTRQLRNSTLQCETINSDN 1068
Score = 58.2 bits (139), Expect = 2e-08
Identities = 114/536 (21%), Positives = 223/536 (41%), Gaps = 81/536 (15%)
Query: 150 MPDWEQSAESLQPVQE----DMALNEV------LQKLKHTNRK--QEVRI-----QELQC 192
M D E AE LQ Q+ +NE+ LQK K +K QE+ + Q+
Sbjct: 1098 MVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTL 1157
Query: 193 SNLYL---EKRVKELQMKIT------------------KQQVFIDVINKLKENVEELIED 231
N+ + E+ +KEL K+T KQ+ + I L+ +V++ E
Sbjct: 1158 MNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEK 1217
Query: 232 KYKIILEKNDTKKTLQNLEE-------VLANTQKHLQESRNDKEMLQLQFKKIKANYVCL 284
KI TKK L + ++ + A+ + L+ S+ E+ ++Q +I + +
Sbjct: 1218 NTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKI 1277
Query: 285 QERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQ-QLKKELEKATASALDLLKREKEA 343
E T +Q +++S Y + L ++ + Q + E E ++LK++K
Sbjct: 1278 HEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQK-- 1335
Query: 344 QEQEFLSLQEEFQKLEKENLEE-----RQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQ 398
+ + E K E+E+LE + KL+ L V LQ + T +
Sbjct: 1336 -NKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHN 1394
Query: 399 QQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQL---EEVLKSDITKDTKTTHSNL 455
+ + E ++ A+L++++ + +N + K E Q QL EVL++ +
Sbjct: 1395 KMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEE- 1453
Query: 456 LPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINS--DAEHFKESEKVSD 513
+ ++ Q SKM + L + T + ++S ++ +E + +D
Sbjct: 1454 -----------HRKTVETLQQQLSKMEAQLFQLKNEPTTRSPVSSQQSLKNLRE-RRNTD 1501
Query: 514 IMLQKLKSLHLKK----KTLDKEVIDCDSDEAKSIRDVPTLLGAKLDK--YHS--LNEEL 565
+ L + ++ ++ +T D E + S +S+ + KL+ +H+ EEL
Sbjct: 1502 LPLLDMHTVTREEGEGMETTDTESVSSASTYTQSLEQLLNSPETKLEPPLWHAEFTKEEL 1561
Query: 566 DFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRK-PREKARKPRSKSLE 620
++S + + + L + + A L E+ K L+ IR+ R + R+ + +LE
Sbjct: 1562 VQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSAANLE 1617
Score = 55.5 bits (132), Expect = 2e-07
Identities = 102/480 (21%), Positives = 203/480 (42%), Gaps = 67/480 (13%)
Query: 181 RKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELIEDKYK-----I 235
+KQ + IQ+ + LEK ++EL+ K + D+I L E ++ L+ +K + +
Sbjct: 35 KKQMMLIQKAKSRCTELEKEIEELRSKPVTEGTG-DIIKALTERLDALLLEKAETEQQCL 93
Query: 236 ILEKNDTKKTLQ-------------NLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYV 282
L+K + K + LE+ N K ++ +N+ ++ ++ + KAN
Sbjct: 94 SLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQ 153
Query: 283 CLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQ--------QLKKELE------K 328
E M + ++ + + + K +EE+E+++ L+K+L+ K
Sbjct: 154 KQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKK 213
Query: 329 ATASAL-DLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLL----TQVRNL 383
T + L ++++ + ++ SLQEE +L+ + EE ++L ++E ++ L
Sbjct: 214 ETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKL 273
Query: 384 QFMSEN------ERTKNIKLQQQINEVKN-----ENAKLKQQVAR--SEEQNYVPKFETA 430
+ EN KNI+ + + E++N NA Q+ +E +V +
Sbjct: 274 NELKENLVKQCEASEKNIQKKYEC-ELENLRKATSNANQDNQICSILLQENTFVEQVVNE 332
Query: 431 QLKDQLEEVLKS-----DITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLL 485
++K LE+ LK I KD T +NL + + L K++ LL
Sbjct: 333 KVK-HLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELL 391
Query: 486 ALMVGLLTCQDIINSDA----EHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEA 541
+ + S+ + F + + + +Q LK H K+ + E DS++
Sbjct: 392 LAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSDSEKE 451
Query: 542 KSIRDVPTLLGAKLDKYHSLNEELDFLVTSYE---EIIECADQRLAISHSQIAHLEERNK 598
K + + + G K ++ +L +E + +YE EI+E L S +I+ E K
Sbjct: 452 K-LTLMFEIQGLK-EQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMK 509
Score = 55.5 bits (132), Expect = 2e-07
Identities = 93/474 (19%), Positives = 217/474 (45%), Gaps = 72/474 (15%)
Query: 168 ALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEE 227
+L E L +LK ++++ ++EL C +E KE + +I K +N+LKEN+ +
Sbjct: 236 SLQEELLQLKAIHQEE---VKELMCQ---IEASAKEHEAEINK-------LNELKENLVK 282
Query: 228 LIEDKYKIILEKNDTKKTLQNLEEVLANTQKH-------LQESR------NDK-EMLQLQ 273
E K I +K + + L+NL + +N + LQE+ N+K + L+
Sbjct: 283 QCEASEKNIQKKYECE--LENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDT 340
Query: 274 FKKIKANYVCLQER--YMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATA 331
K++++ + L++ YM ++ K + +Q+++ D+ ++E+ ++ +L
Sbjct: 341 LKELESQHSILKDEVTYMNNLKLKLEMDAQHIK-DEFFHEREDLEFKINEL--------- 390
Query: 332 SALDLLKREK-----EAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFM 386
LL +E+ E + E L ++F +++ E Q LK + +K ++++ N F+
Sbjct: 391 ----LLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISEL-NETFL 445
Query: 387 SENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSD--- 443
S++E+ K + L +I +K + L+Q E+Q + +E+ + ++ E+L+++
Sbjct: 446 SDSEKEK-LTLMFEIQGLKEQCENLQQ-----EKQEAILNYESLR---EIMEILQTELGE 496
Query: 444 ----ITKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIIN 499
I+++ ++ D +++L A ++ L ++ L LL+ Q+++
Sbjct: 497 SAGKISQEFESMKQQQASDVHELQQKLRTAFTEK-DALLETVNRLQGENEKLLSQQELVP 555
Query: 500 SDAEHFKESEKVSDIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYH 559
K ++ + + L L K L+ ++ ++ I + ++D +H
Sbjct: 556 ELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKN-SHEEMDNFH 614
Query: 560 SLNEELDFLVTSYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKPREKARK 613
E + L+ E+ + +Q + + + E LE+ +++ + +K
Sbjct: 615 KKCEREERLIL---ELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQK 665
Score = 53.1 bits (126), Expect = 8e-07
Identities = 99/465 (21%), Positives = 190/465 (40%), Gaps = 52/465 (11%)
Query: 170 NEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKENVEELI 229
N +Q LK ++K+ + E S+ EK + I LKE E L
Sbjct: 423 NREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFE------------IQGLKEQCENLQ 470
Query: 230 EDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYM 289
++K + IL ++ ++ L+ L + + S+ + M Q Q + LQ++
Sbjct: 471 QEKQEAILNYESLREIMEILQTELGESAGKI--SQEFESMKQQQASDVHE----LQQKLR 524
Query: 290 TEMQQKN---KSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATA------SALDLLKRE 340
T +K+ ++V++ ++ L ++E V L+ K L++ S D + +E
Sbjct: 525 TAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKE 584
Query: 341 KEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQ 400
E + +++F K + EE + E+ + L E N +L+Q+
Sbjct: 585 LEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQK 644
Query: 401 INEVK---NENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLP 457
+NE+ E K K Q + E+ V ++ K+ L +KS ++ K + S
Sbjct: 645 VNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLS-SEKKQ 703
Query: 458 DCSPCEERLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQ 517
E L+ + + +++ L LMV QD +N E+E+V + ++
Sbjct: 704 LSRDLEVFLSQKEDVILKEHITQLEKKLQLMV---EEQDNLNK----LLENEQVQKLFVK 756
Query: 518 KLKSLHLKKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEE-------LDFLVT 570
L+ K + EV + DS+E +DV +L A + +NEE D V
Sbjct: 757 --TQLYGFLKEMGSEVSE-DSEE----KDVVNVLQAVGESLAKINEEKCNLAFQRDEKVL 809
Query: 571 SYEEIIECADQRLAISHSQIAHLEERNKHLEDLIRKPREKARKPR 615
E+ I+C + + ++ L + + L+RK E+ + +
Sbjct: 810 ELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEK 854
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.336
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,114,611
Number of Sequences: 37866
Number of extensions: 1101675
Number of successful extensions: 17930
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 487
Number of HSP's successfully gapped in prelim test: 1294
Number of HSP's that attempted gapping in prelim test: 6357
Number of HSP's gapped (non-prelim): 5750
length of query: 641
length of database: 18,247,518
effective HSP length: 109
effective length of query: 532
effective length of database: 14,120,124
effective search space: 7511905968
effective search space used: 7511905968
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.