Guide to the Human Genome
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Search of human proteins with 45446747

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
         (938 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]           1910   0.0  
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]           1910   0.0  
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   399   e-111
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         373   e-103
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          373   e-103
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    362   e-100
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   294   2e-79
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  285   2e-76
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...   278   1e-74
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   277   3e-74
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   268   1e-71
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   268   1e-71
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   268   1e-71
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   261   2e-69
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   252   1e-66
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   252   1e-66
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   239   9e-63
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   224   3e-58
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   211   3e-54
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   202   2e-51
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   202   2e-51
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   199   1e-50
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ...   193   7e-49
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   187   3e-47
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi...   183   7e-46
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi...   183   7e-46
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      181   3e-45
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi...   180   5e-45
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   177   4e-44
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   176   7e-44

>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score = 1910 bits (4948), Expect = 0.0
 Identities = 938/938 (100%), Positives = 938/938 (100%)

Query: 1   MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 60
           MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY
Sbjct: 1   MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 60

Query: 61  KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 120
           KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM
Sbjct: 61  KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 120

Query: 121 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 180
           AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN
Sbjct: 121 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 180

Query: 181 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 240
           LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN
Sbjct: 181 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 240

Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
           LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG
Sbjct: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300

Query: 301 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360
           SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV
Sbjct: 301 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360

Query: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 420
           YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ
Sbjct: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 420

Query: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480
           VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS
Sbjct: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480

Query: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
           GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV
Sbjct: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540

Query: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
           ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT
Sbjct: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600

Query: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 660
           LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY
Sbjct: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 660

Query: 661 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 720
           RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK
Sbjct: 661 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 720

Query: 721 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 780
           AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP
Sbjct: 721 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 780

Query: 781 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 840
           SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH
Sbjct: 781 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 840

Query: 841 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 900
           GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM
Sbjct: 841 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 900

Query: 901 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 938
           EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS
Sbjct: 901 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 938


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score = 1910 bits (4948), Expect = 0.0
 Identities = 938/938 (100%), Positives = 938/938 (100%)

Query: 1   MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 60
           MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY
Sbjct: 1   MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 60

Query: 61  KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 120
           KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM
Sbjct: 61  KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 120

Query: 121 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 180
           AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN
Sbjct: 121 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 180

Query: 181 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 240
           LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN
Sbjct: 181 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 240

Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
           LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG
Sbjct: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300

Query: 301 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360
           SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV
Sbjct: 301 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360

Query: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 420
           YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ
Sbjct: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 420

Query: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480
           VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS
Sbjct: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480

Query: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
           GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV
Sbjct: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540

Query: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
           ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT
Sbjct: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600

Query: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 660
           LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY
Sbjct: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 660

Query: 661 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 720
           RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK
Sbjct: 661 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 720

Query: 721 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 780
           AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP
Sbjct: 721 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 780

Query: 781 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 840
           SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH
Sbjct: 781 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 840

Query: 841 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 900
           GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM
Sbjct: 841 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 900

Query: 901 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 938
           EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS
Sbjct: 901 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 938


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  399 bits (1024), Expect = e-111
 Identities = 235/603 (38%), Positives = 347/603 (57%), Gaps = 42/603 (6%)

Query: 77  EDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEE 136
           ED+++D  +      PAE      +   + +D      PL+A+M EV+++  +   R  +
Sbjct: 201 EDDDDDEDD------PAEAEKEGNEMEGEELD------PLDAYMEEVKEEVKKFNMRSVK 248

Query: 137 KD--KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPI---- 190
                E+K+   +   +     ++A    +  +   G + E ++D +EY S+   +    
Sbjct: 249 GGGGNEKKSGPTVTKVVTVVTTKKAV---VDSDKKKGELMENDQDAMEYSSEEEEVDLQT 305

Query: 191 ------APTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN-LRV 243
                    +K+++P   +DH +I+Y PF KNFY E  E+  ++ +++   R ++  + V
Sbjct: 306 ALTGYQTKQRKLLEP---VDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITV 362

Query: 244 SGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGK 303
            G   P+P  S+   G   ++++ ++K  Y +PTPIQ Q +P  +SGRD+IGIAKTGSGK
Sbjct: 363 KGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGK 422

Query: 304 TAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGG 363
           T AF+ PM  HIMDQ+ LE G+GPIAVI+ PTREL  QI  ECK+F K   LR V VYGG
Sbjct: 423 TIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGG 482

Query: 364 GSMWEQAKALQEGAEIVVCTPGRLIDHV---KKKATNLQRVSYLVFDEADRMFDMGFEYQ 420
             + EQ   L+ GAEI+VCTPGR+ID +     + TNL+RV+Y+V DEADRMFDMGFE Q
Sbjct: 483 TGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQ 542

Query: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480
           V  I  +VRPDRQT++FSATF + +E LAR IL  PI V  G       DV Q V ++  
Sbjct: 543 VMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEE 602

Query: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
              K+  L   L  +  SGSV++FV K+ +A+ L  +L +  +    LHG +DQ +R+ +
Sbjct: 603 -EKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSI 661

Query: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
           I+DFK     +LVAT VAARGLD+  +  V+NY      + + HR GRTGRAG KG AYT
Sbjct: 662 INDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYT 721

Query: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAW--FRKSRFKGGKGKKLNIGGGGL 658
            +T   + +AGD+++ LE +   V  +L     +  W  F+  +   GK  K + G  G 
Sbjct: 722 FITEDQARYAGDIIKALELSGTAVPPDL-----EKLWSDFKDQQKAEGKIIKKSSGFSGK 776

Query: 659 GYR 661
           G++
Sbjct: 777 GFK 779



 Score = 31.6 bits (70), Expect = 3.6
 Identities = 35/139 (25%), Positives = 47/139 (33%), Gaps = 16/139 (11%)

Query: 797 REGTGGSNGKRERYTE------NRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESS 850
           R  + G +G R R          RG  R S     +R  +  R  D  R     R     
Sbjct: 11  RSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRR 70

Query: 851 SRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKMEPKVDS---- 906
           SR  +  R  E R   S  R   +R  + GR   S     N+  K E +   K  +    
Sbjct: 71  SRSRERDRSRERRRSRSRDRR-RSRSRSRGRRSRSSSPG-NKSKKTENRSRSKEKTDGGE 128

Query: 907 ----SKMDKVDSKTDKTAD 921
                K DK D + +K  D
Sbjct: 129 SSKEKKKDKDDKEDEKEKD 147


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  373 bits (957), Expect = e-103
 Identities = 224/620 (36%), Positives = 339/620 (54%), Gaps = 42/620 (6%)

Query: 174 QEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDY---PPFEKNFYNEHEEITNLTPQ 230
           ++ + D   + + G    P KK  +P   +   + D    P FEKNFY EH E+  LTP 
Sbjct: 88  RDRDRDRGGFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPY 147

Query: 231 QLIDLRHKLNLRVSGA-APPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALS 289
           ++ +LR K  + V G    P+P  +F H  F + +M  +    +T+PTPIQCQG P+ALS
Sbjct: 148 EVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALS 207

Query: 290 GRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRF 349
           GRDM+GIA+TGSGKT A++ P ++HI  Q  LE GDGPI +++ PTREL QQ+      +
Sbjct: 208 GRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDY 267

Query: 350 GKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEA 409
           GK   L+S  +YGG     Q + L+ G EI + TPGRLID ++   TNL+R +YLV DEA
Sbjct: 268 GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEA 327

Query: 410 DRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIG-EAN 468
           DRM DMGFE Q+R I   +RPDRQTL++SAT+ K++ +LA D L D  ++  G++   AN
Sbjct: 328 DRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSAN 387

Query: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFVTKKANAEELANNLKQEGHNLG 526
            ++ QIV++      K + L + + E  +      ++FV  K   ++L   ++++G    
Sbjct: 388 HNILQIVDVCMES-EKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAM 446

Query: 527 LLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRI 586
            +HGD  Q ER+ V+++F+    P+L+ATDVA+RGLD+  +K VINYD     + + HRI
Sbjct: 447 CIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRI 506

Query: 587 GRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646
           GRT R+  KG AYT  TP +   A +L++ LE ANQ ++ +L+ L          R  GG
Sbjct: 507 GRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLV-------DHRGGGG 559

Query: 647 KGKKLNIGGGGLGYRERPGLGSENM---DRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAF 703
            G K    GG   YR      + N+   D  +  +    +  +  + +  DR    +A +
Sbjct: 560 GGGK----GGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGY 615

Query: 704 ---------QSQYKSHFVAASLSNQKAGSSAAGASGWTS----AGSLNSVPTNSAQQGHN 750
                     S + +     +      G++A G S +T+    AG+  +  T S   G +
Sbjct: 616 ANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTTST--GRS 673

Query: 751 SPDSPVTSAAKGIPGFGNTG 770
           S      S+++   G G +G
Sbjct: 674 S-----QSSSQQFSGIGRSG 688


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  373 bits (957), Expect = e-103
 Identities = 223/620 (35%), Positives = 338/620 (54%), Gaps = 44/620 (7%)

Query: 174 QEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDY---PPFEKNFYNEHEEITNLTPQ 230
           ++ + D   + + G    P KK  +P   +   + D    P FEKNFY EH E+  LTP 
Sbjct: 88  RDRDRDRGGFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPY 147

Query: 231 QLIDLRHKLNLRVSGA-APPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALS 289
           ++ +LR K  + V G    P+P  +F H  F + +M  +    +T+PTPIQCQG P+ALS
Sbjct: 148 EVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALS 207

Query: 290 GRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRF 349
           GRDM+GIA+TGSGKT A++ P ++HI  Q  LE GDGPI +++ PTREL QQ+      +
Sbjct: 208 GRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDY 267

Query: 350 GKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEA 409
           GK   L+S  +YGG     Q + L+ G EI + TPGRLID ++   TNL+R +YLV DEA
Sbjct: 268 GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEA 327

Query: 410 DRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIG-EAN 468
           DRM DMGFE Q+R I   +RPDRQTL++SAT+ K++ +LA D L D  ++  G++   AN
Sbjct: 328 DRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSAN 387

Query: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFVTKKANAEELANNLKQEGHNLG 526
            ++ QIV++      K + L + + E  +      ++FV  K   ++L   ++++G    
Sbjct: 388 HNILQIVDVCMES-EKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAM 446

Query: 527 LLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRI 586
            +HGD  Q ER+ V+++F+    P+L+ATDVA+RGLD+  +K VINYD     + + HRI
Sbjct: 447 CIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRI 506

Query: 587 GRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646
           GRT R+  KG AYT  TP +   A +L++ LE ANQ ++ +L+ L             GG
Sbjct: 507 GRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRG--------GG 558

Query: 647 KGKKLNIGGGGLGYRERPGLGSENM---DRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAF 703
            G     GGG   YR      + N+   D  +  +    +  +  + +  DR    +A +
Sbjct: 559 GG-----GGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGY 613

Query: 704 ---------QSQYKSHFVAASLSNQKAGSSAAGASGWTS----AGSLNSVPTNSAQQGHN 750
                     S + +     +      G++A G S +T+    AG+  +  T S   G +
Sbjct: 614 ANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTTST--GRS 671

Query: 751 SPDSPVTSAAKGIPGFGNTG 770
           S      S+++   G G +G
Sbjct: 672 S-----QSSSQQFSGIGRSG 686


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  362 bits (929), Expect = e-100
 Identities = 213/552 (38%), Positives = 311/552 (56%), Gaps = 37/552 (6%)

Query: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQI 268
           + P FEKNFY EH ++   T Q++   R    + V G   P+P  +F    F   +M  I
Sbjct: 50  ELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVI 109

Query: 269 RKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPI 328
            +  +T+PT IQ QG PVALSG DM+G+A+TGSGKT +++ P ++HI  Q  LE GDGPI
Sbjct: 110 ARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPI 169

Query: 329 AVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLI 388
            +++ PTREL QQ+      + +A  L+S  +YGG     Q + L+ G EI + TPGRLI
Sbjct: 170 CLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLI 229

Query: 389 DHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKL 448
           D ++   TNL+R +YLV DEADRM DMGFE Q+R I   +RPDRQTL++SAT+ K++ +L
Sbjct: 230 DFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQL 289

Query: 449 ARDILIDPIRVVQGDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFV 505
           A D L D I +  G +   AN ++ QIV++ H    K   L R + E  S      ++FV
Sbjct: 290 AEDFLKDYIHINIGALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFV 348

Query: 506 TKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIP 565
             K   +EL   ++++G     +HGD  Q ER+ V+++FK    P+L+ATDVA+RGLD+ 
Sbjct: 349 ETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVE 408

Query: 566 SIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVS 625
            +K VINYD     + + HRIGRT R+ + G AYT  TP +     DL+  L  ANQ ++
Sbjct: 409 DVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAIN 468

Query: 626 KELLDLAMQNAWFRKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVM 679
            +LL L +++    +SR +GG    +  + + G  GG   +R+R     EN DRG ++++
Sbjct: 469 PKLLQL-VEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLL 522

Query: 680 SNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNS 739
                 K   G                    + AA+ +N   GS+   A   TS  + N 
Sbjct: 523 KRDFGAKTQNGV-------------------YSAANYTNGSFGSNFVSAGIQTSFRTGN- 562

Query: 740 VPTNSAQQGHNS 751
            PT + Q G++S
Sbjct: 563 -PTGTYQNGYDS 573


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  294 bits (753), Expect = 2e-79
 Identities = 169/452 (37%), Positives = 262/452 (57%), Gaps = 20/452 (4%)

Query: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVS------GAAPPRPGSSFAH---FG 259
           D PP +KNFY E    + ++  +  D   K N  ++      G   P P  +      F 
Sbjct: 190 DLPPIKKNFYKESTATSAMSKVEA-DSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQ 248

Query: 260 FDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK 319
              ++M  I+K+ + +PTPIQ Q  P+ L G D+IG+A+TG+GKT  ++ P  IH++ Q 
Sbjct: 249 CYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQP 308

Query: 320 ELE-PGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAE 378
            L+   + P  +++ PTREL  Q+  EC ++     LRSV VYGGG+  EQ + L++G +
Sbjct: 309 SLKGQRNRPGMLVLTPTRELALQVEGECCKYSYK-GLRSVCVYGGGNRDEQIEELKKGVD 367

Query: 379 IVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFS 438
           I++ TPGRL D       NL+ ++YLV DEAD+M DMGFE Q+  I   VRPDRQT++ S
Sbjct: 368 IIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTS 427

Query: 439 ATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSS 498
           AT+   + +LA+  L +P+ V  G +        +   I+ +   KW+ +   L   +S+
Sbjct: 428 ATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSST 487

Query: 499 GSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558
             V++FV++KA A+ L+++L     ++  LHGD +Q +R K + +FK   + +L+ATD+A
Sbjct: 488 DKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLA 547

Query: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLE 618
           +RGLD+  +  V N+D  R+I+ + HRIGRTGRAG  GV+ T LT  D   A +L+  LE
Sbjct: 548 SRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILE 607

Query: 619 GANQHVSKELLDLAMQNAWFRKSRFKGGKGKK 650
            ANQ + +EL+ +A         RFK  + K+
Sbjct: 608 RANQSIPEELVSMA--------ERFKAHQQKR 631


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  285 bits (728), Expect = 2e-76
 Identities = 214/622 (34%), Positives = 308/622 (49%), Gaps = 64/622 (10%)

Query: 65  KRANFDEENAY-FEDEEEDSSNVD-LPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAE 122
           KRA  DE  A     E ED  + D +PY+P      RQ    K +             AE
Sbjct: 9   KRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQR--RQLLLQKLLQRRRKG------AAE 60

Query: 123 VEDQAARDMKRLEEKD---KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQE---E 176
            E Q +    R +E D     + NV  +        DQ  + +  AE       ++   E
Sbjct: 61  EEQQDSGSEPRGDEDDIPLGPQSNVSLL--------DQHQHLKEKAEARKESAKEKQLKE 112

Query: 177 EEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLR 236
           EE  LE  ++G  +   K++           I Y    K  +     + +++ ++   +R
Sbjct: 113 EEKILESVAEGRALMSVKEMA--------KGITYDDPIKTSWTPPRYVLSMSEERHERVR 164

Query: 237 HKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGI 296
            K ++ V G   P P  SF    F   ++  ++K     PTPIQ QG+P  LSGRDMIGI
Sbjct: 165 KKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGI 224

Query: 297 AKTGSGKTAAFIWPMLIHIMDQKELEP---GDGPIAVIVCPTRELCQQIHAECKRFGKAY 353
           A TGSGKT  F  P+++  ++Q++  P    +GP  +I+CP+REL +Q H   + + +  
Sbjct: 225 AFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLL 284

Query: 354 N------LRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFD 407
                  LR     GG S+ EQ + ++ G  ++V TPGRL+D ++KK  +L    YL  D
Sbjct: 285 QEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALD 344

Query: 408 EADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEA 467
           EADRM DMGFE  +R+I S+ +  RQTLLFSAT  KKI+  A+  L+ P+ +  G  G A
Sbjct: 345 EADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAA 404

Query: 468 NEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGL 527
           + DV Q VE +    +K  +L   L +  +   VL+F  KKA+ + +   L  +G     
Sbjct: 405 SLDVIQEVEYVKE-EAKMVYLLECLQK--TPPPVLIFAEKKADVDAIHEYLLLKGVEAVA 461

Query: 528 LHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIG 587
           +HG  DQ ER K I  F++    VLVATDVA++GLD P+I+ VINYD+  +I+ + HRIG
Sbjct: 462 IHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIG 521

Query: 588 RTGRAGEKGVAYTLLTPK-DSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646
           RTGR+G  G+A T +    D +   DL   L  A Q V   L  L              G
Sbjct: 522 RTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHC------------G 569

Query: 647 KGKKLNIGG-------GGLGYR 661
               L+IGG       GGLG+R
Sbjct: 570 DESMLDIGGERGCAFCGGLGHR 591


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score =  278 bits (712), Expect = 1e-74
 Identities = 163/453 (35%), Positives = 265/453 (58%), Gaps = 14/453 (3%)

Query: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRV------SGAAP--PRPGSSFAH-FG 259
           D PP +KNFY E +  + ++  Q+I+ R K N  +      SG     P+P   F   F 
Sbjct: 170 DLPPVKKNFYIESKATSCMSEMQVINWR-KENFNITCDDLKSGEKRLIPKPTCRFKDAFQ 228

Query: 260 FDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK 319
               L+  I +    +PTPIQ Q  P+ L G D+I +A+TG+GKT +++ P  IH+  Q 
Sbjct: 229 QYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQP 288

Query: 320 -ELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAE 378
              E  +GP  +++ PTREL   + AEC ++     L+S+ +YGG +   Q + + +G +
Sbjct: 289 ISREQRNGPGMLVLTPTRELALHVEAECSKYSYK-GLKSICIYGGRNRNGQIEDISKGVD 347

Query: 379 IVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFS 438
           I++ TPGRL D     + NL+ ++YLV DEAD+M DM FE Q+R I   VRPDRQT++ S
Sbjct: 348 IIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTS 407

Query: 439 ATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTS- 497
           AT+   + +LA   L DP+ V  G++     +  +   I+ +   K   LT+  VE  S 
Sbjct: 408 ATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEK-RALTQEFVENMSP 466

Query: 498 SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDV 557
           +  V++FV++K  A++L+++   +G +   LHG+ +QS++ + + DFK  +I +L+ TD+
Sbjct: 467 NDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526

Query: 558 AARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNL 617
            +RGLD+  +  V NYD  R+ID + HR+G  GR G+ G + TL+T +DS  AG+L++ L
Sbjct: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586

Query: 618 EGANQHVSKELLDLAMQNAWFRKSRFKGGKGKK 650
           + ANQ V ++L+ +A Q    ++ R +  + +K
Sbjct: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRK 619


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  277 bits (709), Expect = 3e-74
 Identities = 162/416 (38%), Positives = 234/416 (56%), Gaps = 32/416 (7%)

Query: 222 EEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQC 281
           +++  +T +     R   ++   G   P P  S+        ++  I K  Y +PTPIQ 
Sbjct: 360 KKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQR 419

Query: 282 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKEL----EPGDGPIAVIVCPTRE 337
           Q +P+ L  RD+IG+A+TGSGKTAAF+ P+L+ I    ++    E   GP A+I+ PTRE
Sbjct: 420 QAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRE 479

Query: 338 LCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATN 397
           L QQI  E  +FGK   +R+VAV GG S  +Q   L+ G EIV+ TPGRLID ++ +   
Sbjct: 480 LAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLV 539

Query: 398 LQRVSYLVFDEADRMFDMGFEYQVRSIASHV-----RPD--------------------- 431
           L R +Y+V DEADRM DMGFE  V+ I  H+     +PD                     
Sbjct: 540 LSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKY 599

Query: 432 RQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRR 491
           RQT++F+AT    +E+LAR  L  P  V  G  G+ +E V Q V ++     +   L   
Sbjct: 600 RQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLA-- 657

Query: 492 LVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPV 551
           ++E      +++FV +K   + LA +L++ G+N   LHG   Q +R   +S+ K     +
Sbjct: 658 ILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDI 717

Query: 552 LVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDS 607
           LVATDVA RG+DI  +  V+NYD+A++I+ + HRIGRTGRAG+ GVA T LT +DS
Sbjct: 718 LVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDS 773



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 23/110 (20%), Positives = 48/110 (43%), Gaps = 2/110 (1%)

Query: 794 NNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPR-HGDGGRHGDGYRHPESSSR 852
           +  R+ +   + KR R  + R     S   + ++ ++  R H +  R  +  R+ +   R
Sbjct: 33  DRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERERDKERDRNKKDRDR 92

Query: 853 HTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKMEP 902
             DGHR  ++R   S    G  +     ++ +S+K+  +     +PK +P
Sbjct: 93  DKDGHRRDKDRKRSSLS-PGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQP 141


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  268 bits (686), Expect = 1e-71
 Identities = 161/437 (36%), Positives = 238/437 (54%), Gaps = 25/437 (5%)

Query: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313
           SF+     E +M  I  + YT+PTP+Q   +P+    RD++  A+TGSGKTAAF+ P+L 
Sbjct: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240

Query: 314 HIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHAECKRFGKAYNLRS 357
            I       PG+                 PI++++ PTREL  QI+ E ++F     +R 
Sbjct: 241 QIYSDG---PGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRP 297

Query: 358 VAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGF 417
             VYGG  + +Q + L+ G  ++V TPGRL+D +++    L    YLV DEADRM DMGF
Sbjct: 298 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 357

Query: 418 EYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQ 473
           E Q+R I        +  R T++FSATF K+I+ LARD L + I +  G +G  +E++TQ
Sbjct: 358 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 417

Query: 474 IVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMD 533
            V  +     K ++L   L         L+FV  K  A+ L + L  EG+    +HGD  
Sbjct: 418 KVVWVEES-DKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRS 476

Query: 534 QSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAG 593
           Q +R + +  F+    P+LVAT VAARGLDI ++K VIN+D+  DI+ + HRIGRTGR G
Sbjct: 477 QRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 536

Query: 594 EKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNI 653
             G+A +    ++ N   DL+  L  A Q V   L ++A ++ +   SR +  K  + + 
Sbjct: 537 NLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGR-SKSSRFSG 595

Query: 654 GGGGLGYRERPGLGSEN 670
           G G   YR+  G  S +
Sbjct: 596 GFGARDYRQSSGASSSS 612


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  268 bits (686), Expect = 1e-71
 Identities = 165/459 (35%), Positives = 248/459 (54%), Gaps = 27/459 (5%)

Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
           +  +G+  P    +F+     E +M  I  + YT+PTP+Q   +P+    RD++  A+TG
Sbjct: 166 VEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTG 225

Query: 301 SGKTAAFIWPMLIHIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHA 344
           SGKTAAF+ P+L  I       PG+                 PI++++ PTREL  QI+ 
Sbjct: 226 SGKTAAFLLPILSQIYTDG---PGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYE 282

Query: 345 ECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYL 404
           E ++F     +R   VYGG  + +Q + L+ G  ++V TPGRL+D +++    L    YL
Sbjct: 283 EARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYL 342

Query: 405 VFDEADRMFDMGFEYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVV 460
           V DEADRM DMGFE Q+R I        +  R T++FSATF K+I+ LARD L + I + 
Sbjct: 343 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLA 402

Query: 461 QGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ 520
            G +G  +E++TQ V +      K ++L   L    S    L+FV  K  A+ L + L  
Sbjct: 403 VGRVGSTSENITQKV-VWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYH 461

Query: 521 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID 580
           EG+    +HGD  Q +R + +  F+    P+LVAT VAARGLDI +++ VIN+D+  DI+
Sbjct: 462 EGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIE 521

Query: 581 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK 640
            + HRIGRTGR G  G+A +    K+ N   DL+  L  A Q V   L ++A ++ +   
Sbjct: 522 EYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGG 581

Query: 641 SRFKGGKGKKLNIGGGGLGYRERPGLGSENM--DRGNNN 677
           SR +  K  + + G G   YR+  G  S      RG+++
Sbjct: 582 SRGR-SKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSS 619


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  268 bits (686), Expect = 1e-71
 Identities = 165/459 (35%), Positives = 248/459 (54%), Gaps = 27/459 (5%)

Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
           +  +G+  P    +F+     E +M  I  + YT+PTP+Q   +P+    RD++  A+TG
Sbjct: 166 VEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTG 225

Query: 301 SGKTAAFIWPMLIHIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHA 344
           SGKTAAF+ P+L  I       PG+                 PI++++ PTREL  QI+ 
Sbjct: 226 SGKTAAFLLPILSQIYTDG---PGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYE 282

Query: 345 ECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYL 404
           E ++F     +R   VYGG  + +Q + L+ G  ++V TPGRL+D +++    L    YL
Sbjct: 283 EARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYL 342

Query: 405 VFDEADRMFDMGFEYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVV 460
           V DEADRM DMGFE Q+R I        +  R T++FSATF K+I+ LARD L + I + 
Sbjct: 343 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLA 402

Query: 461 QGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ 520
            G +G  +E++TQ V +      K ++L   L    S    L+FV  K  A+ L + L  
Sbjct: 403 VGRVGSTSENITQKV-VWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYH 461

Query: 521 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID 580
           EG+    +HGD  Q +R + +  F+    P+LVAT VAARGLDI +++ VIN+D+  DI+
Sbjct: 462 EGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIE 521

Query: 581 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK 640
            + HRIGRTGR G  G+A +    K+ N   DL+  L  A Q V   L ++A ++ +   
Sbjct: 522 EYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGG 581

Query: 641 SRFKGGKGKKLNIGGGGLGYRERPGLGSENM--DRGNNN 677
           SR +  K  + + G G   YR+  G  S      RG+++
Sbjct: 582 SRGR-SKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSS 619


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  261 bits (667), Expect = 2e-69
 Identities = 206/660 (31%), Positives = 313/660 (47%), Gaps = 99/660 (15%)

Query: 7   GPGTKRGFGFGGFAISA--GKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFYKIGS 64
           GP  +  F   GFA     G ++  +  ++ +     TS+  GFG            +G 
Sbjct: 47  GPSRRDHFMKSGFASGRNFGNRDAGECNKRDN-----TSTMGGFG------------VGK 89

Query: 65  KRANFDEENAYFEDEEE-----DSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDD----- 114
              N    N+ FED +      +SSN        E++PTR +  SK  D+D D D     
Sbjct: 90  SFGNRGFSNSRFEDGDSSGFWRESSN------DCEDNPTRNRGFSKRGDNDLDPDECMQR 143

Query: 115 ---------PLEAFMAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMA 165
                    P+ +     +   +R          ER   KG+ +++     + ++     
Sbjct: 144 TGGLFGSRRPVLSGTGNGDTSQSRS-----GSGSERGGYKGLNEEVITGSGKNSW----- 193

Query: 166 ENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEIT 225
                   + E E     D+ G    P    I P PP D         E + +  ++   
Sbjct: 194 --------KSEAEGGESSDTQG----PKVTYIPPPPPED---------EDSIFAHYQTGI 232

Query: 226 NLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVP 285
           N       D    + + VSG   P    +F      + L + I K+ YT+ TP+Q   +P
Sbjct: 233 NF------DKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIP 286

Query: 286 VALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQ-------KELEPGDGPIAVIVCPTREL 338
           + L+GRD++  A+TGSGKTAAF+ P+L H+M         KEL+    P  +IV PTREL
Sbjct: 287 IILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE---PECIIVAPTREL 343

Query: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNL 398
             QI+ E ++F     +R+V +YGG  +    + + +G  I+  TPGRL+D + K+   L
Sbjct: 344 VNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGL 403

Query: 399 QRVSYLVFDEADRMFDMGFEYQVRSIAS----HVRPDRQTLLFSATFRKKIEKLARDIL- 453
           +++ YLV DEADRM DMGF  +++ + S      +  RQTL+FSATF ++I++LA + L 
Sbjct: 404 KQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLK 463

Query: 454 IDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEE 513
            + + V  G +G A  DV Q V  L  G          ++        ++FV  K  A+ 
Sbjct: 464 SNYLFVAVGQVGGACRDVQQTV--LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADF 521

Query: 514 LANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINY 573
           +A  L QE  +   +HGD +Q ER + + DF+    PVLVAT VAARGLDI +++ VIN+
Sbjct: 522 IATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINF 581

Query: 574 DVARDIDTHTHRIGRTGRAGEKGVAYTLL-TPKDSNFAGDLVRNLEGANQHVSKELLDLA 632
           D+   ID + HRIGRTGR G  G A +      D++ A  LV+ L  A Q V   L ++A
Sbjct: 582 DLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 641


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  252 bits (644), Expect = 1e-66
 Identities = 156/405 (38%), Positives = 229/405 (56%), Gaps = 18/405 (4%)

Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
           + VSG   P    +F      + L + I K+ YT+ TP+Q   +P+ L+GRD++  A+TG
Sbjct: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335

Query: 301 SGKTAAFIWPMLIHIMDQ-------KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAY 353
           SGKTAAF+ P+L H+M         KEL+    P  +IV PTREL  QI+ E ++F    
Sbjct: 336 SGKTAAFLLPILAHMMHDGITASRFKELQE---PECIIVAPTRELVNQIYLEARKFSFGT 392

Query: 354 NLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMF 413
            +R+V +YGG  +    + + +G  I+  TPGRL+D + K+   L+++ YLV DEADRM 
Sbjct: 393 CVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452

Query: 414 DMGFEYQVRSIAS----HVRPDRQTLLFSATFRKKIEKLARDIL-IDPIRVVQGDIGEAN 468
           DMGF  +++ + S      +  RQTL+FSATF ++I++LA + L  + + V  G +G A 
Sbjct: 453 DMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGAC 512

Query: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLL 528
            DV Q V  L  G          ++        ++FV  K  A+ +A  L QE  +   +
Sbjct: 513 RDVQQTV--LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSI 570

Query: 529 HGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGR 588
           HGD +Q ER + + DF+    PVLVAT VAARGLDI +++ VIN+D+   ID + HRIGR
Sbjct: 571 HGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGR 630

Query: 589 TGRAGEKGVAYTLL-TPKDSNFAGDLVRNLEGANQHVSKELLDLA 632
           TGR G  G A +      D++ A  LV+ L  A Q V   L ++A
Sbjct: 631 TGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 675


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  252 bits (644), Expect = 1e-66
 Identities = 156/405 (38%), Positives = 229/405 (56%), Gaps = 18/405 (4%)

Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
           + VSG   P    +F      + L + I K+ YT+ TP+Q   +P+ L+GRD++  A+TG
Sbjct: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335

Query: 301 SGKTAAFIWPMLIHIMDQ-------KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAY 353
           SGKTAAF+ P+L H+M         KEL+    P  +IV PTREL  QI+ E ++F    
Sbjct: 336 SGKTAAFLLPILAHMMHDGITASRFKELQE---PECIIVAPTRELVNQIYLEARKFSFGT 392

Query: 354 NLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMF 413
            +R+V +YGG  +    + + +G  I+  TPGRL+D + K+   L+++ YLV DEADRM 
Sbjct: 393 CVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452

Query: 414 DMGFEYQVRSIAS----HVRPDRQTLLFSATFRKKIEKLARDIL-IDPIRVVQGDIGEAN 468
           DMGF  +++ + S      +  RQTL+FSATF ++I++LA + L  + + V  G +G A 
Sbjct: 453 DMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGAC 512

Query: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLL 528
            DV Q V  L  G          ++        ++FV  K  A+ +A  L QE  +   +
Sbjct: 513 RDVQQTV--LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSI 570

Query: 529 HGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGR 588
           HGD +Q ER + + DF+    PVLVAT VAARGLDI +++ VIN+D+   ID + HRIGR
Sbjct: 571 HGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGR 630

Query: 589 TGRAGEKGVAYTLL-TPKDSNFAGDLVRNLEGANQHVSKELLDLA 632
           TGR G  G A +      D++ A  LV+ L  A Q V   L ++A
Sbjct: 631 TGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 675


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  239 bits (610), Expect = 9e-63
 Identities = 152/460 (33%), Positives = 240/460 (52%), Gaps = 17/460 (3%)

Query: 206 SEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLM 265
           SE + P      Y EH  I NL   Q+ +L+ +L + V G    RP   F H    E L 
Sbjct: 156 SEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN 215

Query: 266 HQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGD 325
           H ++KS Y  PTPIQ Q +PV L GRD++  A TGSGKTAAF+ P+++  + + +     
Sbjct: 216 HNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESKT---- 271

Query: 326 GPIAVIVCPTRELCQQIHAECKRFGKAY-NLRSVAVYGGGSMWEQAKALQEGAEIVVCTP 384
            P A+I+ PTREL  QI  + K        +++V + GG  +  Q   LQ+  ++++ TP
Sbjct: 272 -PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATP 330

Query: 385 GRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKK 444
           GRL+D +K+ +  L  V  +V DEAD M  MGF+ QV  I  ++  D QT+L SAT    
Sbjct: 331 GRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTS 390

Query: 445 IEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGS---- 500
           IE+LA  +L +P+R++ G+      +V QI+ +    P+K     ++L E  +       
Sbjct: 391 IEQLASQLLHNPVRIITGEKNLPCANVRQII-LWVEDPAK----KKKLFEILNDKKLFKP 445

Query: 501 -VLLFVTKKANAEELANNL-KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558
            VL+FV  K  A+ L+  + K  G     +H +  Q ER  ++    + D  V+V+T V 
Sbjct: 446 PVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVL 505

Query: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLE 618
            RGLD+ S++ V+N+D+   +D + H+IGR GR G+ G A T +         D+ + ++
Sbjct: 506 GRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVK 565

Query: 619 GANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGL 658
                +  +LL+    +   RK + K  + +   + G  L
Sbjct: 566 PTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLVTGANL 605


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  224 bits (571), Expect = 3e-58
 Identities = 136/356 (38%), Positives = 200/356 (56%), Gaps = 12/356 (3%)

Query: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313
           +F   G  + L     +  +T+PT IQ + +P+AL GRD+IG+A+TGSGKT AF  P+L 
Sbjct: 25  TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84

Query: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373
            +     LE      A+++ PTREL  QI  + +  G +  ++S  + GG     Q+ AL
Sbjct: 85  AL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL 139

Query: 374 QEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR 432
            +   I++ TPGRLIDH++  K  NL+ + YLV DEADR+ +M FE +V  I   +  DR
Sbjct: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199

Query: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWN--WLTR 490
           +T LFSAT  KK++KL R  L +P++       +  E + Q    +   PSK+   +L  
Sbjct: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI---PSKFKDTYLVY 256

Query: 491 RLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIP 550
            L E   + S ++F +   N +  A  L+  G     LHG M QS+R   ++ FK K   
Sbjct: 257 ILNELAGN-SFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARS 315

Query: 551 VLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
           +L+ATDVA+RGLDIP +  V+N+D+      + HR+GRT RAG  G A T +T  D
Sbjct: 316 ILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYD 371


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  211 bits (536), Expect = 3e-54
 Identities = 150/501 (29%), Positives = 248/501 (49%), Gaps = 45/501 (8%)

Query: 123 VEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLE 182
           ++++  +  K+ + +DKE K+ K     +E+E + +            G   +E+ED  E
Sbjct: 117 LDEKIEKVRKKRKTEDKEAKSGK-----LEKEKEAKE-----------GSEPKEQEDLQE 160

Query: 183 YDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLR 242
            D +G+               + SE DY   ++N   + + +     ++      +    
Sbjct: 161 NDEEGSED-------------EASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGF 207

Query: 243 VSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSG 302
              A+      SF        L+  I    + QPTPIQ   +PV L G+D+   A TG+G
Sbjct: 208 FEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTG 267

Query: 303 KTAAFIWPMLIHIMDQKELEPGDGPIA--VIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360
           KTAAF  P+L  ++     +P   P+   +++ PTREL  Q+H+  ++  +  N+ +   
Sbjct: 268 KTAAFALPVLERLI----YKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLA 323

Query: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEY 419
            GG  +  Q  AL+   +I++ TPGRLIDH+    + +L  +  L+ DEADRM D  FE 
Sbjct: 324 VGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEE 383

Query: 420 QVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIV--EI 477
           Q++ I       RQT+LFSAT   +++ LA   L +P+R+       +N DV   +  E 
Sbjct: 384 QMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVN----SNTDVAPFLRQEF 439

Query: 478 LHSGPSKWN---WLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQ 534
           +   P++      +   L+  T +  V+LF   K  A  +   L   G  +G LHG++ Q
Sbjct: 440 IRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQ 499

Query: 535 SERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGE 594
           ++R + +  FK + I +LVATDVAARGLDI  +KTVIN+ +   I  + HR+GRT RAG 
Sbjct: 500 TQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGR 559

Query: 595 KGVAYTLLTPKDSNFAGDLVR 615
            G + +L+   +     ++V+
Sbjct: 560 AGRSVSLVGEDERKMLKEIVK 580


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  202 bits (513), Expect = 2e-51
 Identities = 124/364 (34%), Positives = 183/364 (50%), Gaps = 3/364 (0%)

Query: 250 RPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIW 309
           +    F   G    +   I K  Y  PTPIQ + +PV L G+D++ +A+TGSGKTA F+ 
Sbjct: 93  KKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLL 152

Query: 310 PMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ 369
           PM   +   K      G  A+I+ PTREL  Q     K  GK   L++  + GG  M +Q
Sbjct: 153 PMFERL---KTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQ 209

Query: 370 AKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVR 429
             AL E  +I++ TPGRL+    + +  LQ V Y+VFDEADR+F+MGF  Q++ I + + 
Sbjct: 210 FAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLP 269

Query: 430 PDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT 489
              QT+LFSAT  K + + AR  L +P+ +      + NE +     ++         L 
Sbjct: 270 GGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLH 329

Query: 490 RRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDI 549
                       ++FV  K +AE L   L  +  +   ++  +D + R   ++ F     
Sbjct: 330 LLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKC 389

Query: 550 PVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNF 609
             L+ TD+AARGLDIP +  VINY          HR+GR  RAG  G AY+L+ P +  +
Sbjct: 390 STLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPY 449

Query: 610 AGDL 613
             DL
Sbjct: 450 LLDL 453


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  202 bits (513), Expect = 2e-51
 Identities = 124/364 (34%), Positives = 183/364 (50%), Gaps = 3/364 (0%)

Query: 250 RPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIW 309
           +    F   G    +   I K  Y  PTPIQ + +PV L G+D++ +A+TGSGKTA F+ 
Sbjct: 93  KKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLL 152

Query: 310 PMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ 369
           PM   +   K      G  A+I+ PTREL  Q     K  GK   L++  + GG  M +Q
Sbjct: 153 PMFERL---KTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQ 209

Query: 370 AKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVR 429
             AL E  +I++ TPGRL+    + +  LQ V Y+VFDEADR+F+MGF  Q++ I + + 
Sbjct: 210 FAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLP 269

Query: 430 PDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT 489
              QT+LFSAT  K + + AR  L +P+ +      + NE +     ++         L 
Sbjct: 270 GGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLH 329

Query: 490 RRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDI 549
                       ++FV  K +AE L   L  +  +   ++  +D + R   ++ F     
Sbjct: 330 LLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKC 389

Query: 550 PVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNF 609
             L+ TD+AARGLDIP +  VINY          HR+GR  RAG  G AY+L+ P +  +
Sbjct: 390 STLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPY 449

Query: 610 AGDL 613
             DL
Sbjct: 450 LLDL 453


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  199 bits (505), Expect = 1e-50
 Identities = 135/396 (34%), Positives = 203/396 (51%), Gaps = 30/396 (7%)

Query: 253 SSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPML 312
           + FA  G    L+ Q R+    QPTP+Q   +P  L GRD +G AKTGSGKTAAF+ P+L
Sbjct: 2   AGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPIL 61

Query: 313 IHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKA 372
                QK  E   G   +++ PTREL  QI  + +  GK   L+   + GG  M  QA  
Sbjct: 62  -----QKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALE 116

Query: 373 LQEGAEIVVCTPGRLIDHVKKKAT-NLQRVSYLVFDEADRMFDMG---FEYQVRSIASHV 428
           L     +V+ TPGRL DH++   T +++++ +LV DEADR+ + G   F   + +I + V
Sbjct: 117 LSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAV 176

Query: 429 RPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSG---PSKW 485
              RQTLLFSAT    + +L        +   Q    EA   V+ + ++       P K 
Sbjct: 177 PARRQTLLFSATLTDTLREL------QGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKV 230

Query: 486 N-----WLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
                  L +R  +     S+++F       + L   L++       LH  M Q ER   
Sbjct: 231 KDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAA 290

Query: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
           ++ FK     +L+ATDVA+RGLDIP+++ VIN++       + HR+GRT RAG +G A T
Sbjct: 291 LAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAIT 350

Query: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNA 636
           L+T  D +    LV  +E   + + K+L + +++ A
Sbjct: 351 LVTQYDIH----LVHAIE---EQIKKKLEEFSVEEA 379


>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
           [Homo sapiens]
          Length = 406

 Score =  193 bits (490), Expect = 7e-49
 Identities = 122/354 (34%), Positives = 180/354 (50%), Gaps = 57/354 (16%)

Query: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313
           +F   G  + L     +  +T+PT IQ + +P+AL GRD+IG+A+TGSGKT AF  P+L 
Sbjct: 25  TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84

Query: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373
            +     LE      A+++ PTREL  QI  + +  G +  ++S  + GG     Q+ AL
Sbjct: 85  AL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL 139

Query: 374 QEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR 432
            +   I++ TPGRLIDH++  K  NL+ + YLV DEADR+ +M FE +V  I   +  DR
Sbjct: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199

Query: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRL 492
           +T LFSAT  KK++KL R  L +P++       +  E + Q    +   PSK+       
Sbjct: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI---PSKF------- 249

Query: 493 VEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVL 552
                                                    +S+R   ++ FK K   +L
Sbjct: 250 -----------------------------------------KSKRLGSLNKFKAKARSIL 268

Query: 553 VATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
           +ATDVA+RGLDIP +  V+N+D+      + HR+GRT RAG  G A T +T  D
Sbjct: 269 LATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYD 322


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  187 bits (476), Expect = 3e-47
 Identities = 116/383 (30%), Positives = 195/383 (50%), Gaps = 13/383 (3%)

Query: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313
           +F   G  E L+  I    + +P+ IQ + +   + GRD+I  +++G+GKTA F   +L 
Sbjct: 39  TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVL- 97

Query: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373
             +D +  E      A+I+ PTREL  QI       G   N++  A  GG ++ E  + L
Sbjct: 98  QCLDIQVRETQ----ALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKL 153

Query: 374 QEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQ 433
             G  +V  TPGR+ D +++++   + +  LV DEAD M + GF+ Q+  +  ++ P  Q
Sbjct: 154 DYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQ 213

Query: 434 TLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLV 493
            +L SAT   +I ++    + DPIR++        E + Q    +     K++ L     
Sbjct: 214 VVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYD 273

Query: 494 EFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLV 553
             T + +V+ F   K   + L   +++    +  +HGDM Q ER  ++ +F+     VL+
Sbjct: 274 TLTITQAVI-FCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLI 332

Query: 554 ATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDL 613
           +TDV ARGLD+P +  +INYD+  + + + HRIGR+GR G KGVA   +   D       
Sbjct: 333 STDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDD------- 385

Query: 614 VRNLEGANQHVSKELLDLAMQNA 636
           +R L    Q+ S ++ ++ M  A
Sbjct: 386 IRILRDIEQYYSTQIDEMPMNVA 408


>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
           sapiens]
          Length = 491

 Score =  183 bits (464), Expect = 7e-46
 Identities = 134/396 (33%), Positives = 202/396 (51%), Gaps = 18/396 (4%)

Query: 223 EITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAH----FGFDEQLMHQIRKSEYTQPTP 278
           ++ NL  +++  LR+K  + V G   P P ++F      +  + +L+  I  + +  PTP
Sbjct: 23  KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 82

Query: 279 IQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTREL 338
           IQ Q +PV L GR+++  A TGSGKT AF  P+L+    Q +     G  A+I+ PTREL
Sbjct: 83  IQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM----QLKQPANKGFRALIISPTREL 138

Query: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ-AKALQEGAEIVVCTPGRLIDHVKKK--A 395
             QIH E  +  +    R   ++      ++      +  +I+V TP RLI  +K+    
Sbjct: 139 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPG 198

Query: 396 TNLQRVSYLVFDEADRMFD---MGFEYQVRSIASHVRPDR-QTLLFSATFRKKIEKLARD 451
            +L  V +LV DE+D++F+    GF  Q+ SI       + +  +FSATF   +E+  + 
Sbjct: 199 IDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKL 258

Query: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT-RRLVEFTSSGSVLLFVTKKAN 510
            L + I V  G    A E V Q  E+L  G      L  R LV+   +  VL+FV     
Sbjct: 259 NLDNVISVSIGARNSAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIER 316

Query: 511 AEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTV 570
           A+EL + L  EG N+ ++H +  Q +R+  +  F+   I VL+ T + ARG+D   +  V
Sbjct: 317 AKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLV 376

Query: 571 INYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
           INYD       + HRIGRTGRAG KG A T  T  D
Sbjct: 377 INYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDD 412


>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
           sapiens]
          Length = 599

 Score =  183 bits (464), Expect = 7e-46
 Identities = 134/396 (33%), Positives = 202/396 (51%), Gaps = 18/396 (4%)

Query: 223 EITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAH----FGFDEQLMHQIRKSEYTQPTP 278
           ++ NL  +++  LR+K  + V G   P P ++F      +  + +L+  I  + +  PTP
Sbjct: 131 KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 190

Query: 279 IQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTREL 338
           IQ Q +PV L GR+++  A TGSGKT AF  P+L+    Q +     G  A+I+ PTREL
Sbjct: 191 IQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM----QLKQPANKGFRALIISPTREL 246

Query: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ-AKALQEGAEIVVCTPGRLIDHVKKK--A 395
             QIH E  +  +    R   ++      ++      +  +I+V TP RLI  +K+    
Sbjct: 247 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPG 306

Query: 396 TNLQRVSYLVFDEADRMFD---MGFEYQVRSIASHVRPDR-QTLLFSATFRKKIEKLARD 451
            +L  V +LV DE+D++F+    GF  Q+ SI       + +  +FSATF   +E+  + 
Sbjct: 307 IDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKL 366

Query: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT-RRLVEFTSSGSVLLFVTKKAN 510
            L + I V  G    A E V Q  E+L  G      L  R LV+   +  VL+FV     
Sbjct: 367 NLDNVISVSIGARNSAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIER 424

Query: 511 AEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTV 570
           A+EL + L  EG N+ ++H +  Q +R+  +  F+   I VL+ T + ARG+D   +  V
Sbjct: 425 AKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLV 484

Query: 571 INYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
           INYD       + HRIGRTGRAG KG A T  T  D
Sbjct: 485 INYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDD 520


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  181 bits (459), Expect = 3e-45
 Identities = 147/505 (29%), Positives = 237/505 (46%), Gaps = 57/505 (11%)

Query: 134 LEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPT 193
           LEE + ++K       + ++ D +++   Y ++  +     E  E+ +  D D  P A  
Sbjct: 17  LEESESQKK-------ERQKSDRRKSRHHYDSDEKS-----ETRENGVTDDLDA-PKAKK 63

Query: 194 KKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGS 253
            K+ + L     +E  +      F   H+      P   ID   K + RVS        S
Sbjct: 64  SKMKEKLN--GDTEEGFNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKS 121

Query: 254 S----------------FAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIA 297
           S                F++F   E+ +  ++    T   PIQ +       G+D+I  A
Sbjct: 122 SDNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQA 181

Query: 298 KTGSGKTAAFIWPMLIHIM-DQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLR 356
           +TG+GKT +F  P++  +  +Q+ ++    P  +++ PTREL  Q+  + K   +   L 
Sbjct: 182 RTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLS 239

Query: 357 SVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMG 416
               YGG S   Q   ++ G +I+V TPGR+ DH++    +L ++ ++V DE D+M D+G
Sbjct: 240 VACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLG 299

Query: 417 FEYQVRSIA-----SHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGD-IGEANED 470
           F  QV  I      +    + QTLLFSAT  + + K+A+  +    R  Q D +G+  + 
Sbjct: 300 FAEQVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKS--RYEQVDLVGKMTQK 357

Query: 471 VTQIVEILHSGPSKWNWLTRRLV-------EFTSSGSVLLFVTKKANAEELANN--LKQE 521
               VE L     + +W  R  V          S G  ++F   K N  E+A N  +KQ 
Sbjct: 358 AATTVEHL---AIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQ- 413

Query: 522 GHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDT 581
             N   LHGD+ QS+R   +  F++    VLVAT+VAARGLDIP +  VI     +D+++
Sbjct: 414 --NAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVES 471

Query: 582 HTHRIGRTGRAGEKGVAYTLLTPKD 606
           + HR GRTGRAG  G+      P++
Sbjct: 472 YIHRSGRTGRAGRTGICICFYQPRE 496



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 21/119 (17%)

Query: 753 DSPVTSAAKGIPGFGNTGNISGAPVTYPSAGAQGVNNTASGNNSREGTGGSNGKRERYTE 812
           D P T + +    + ++  I   P   P        NT+S  NSR+ +G S+G+  R   
Sbjct: 635 DVPTTESERLQAEWHDSDWILSVPAKLPEIEEYYDGNTSS--NSRQRSGWSSGRSGR--- 689

Query: 813 NRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESSSRHTDGHRHGENRHGGSAGRH 871
                    G +G R         GGR G   R    S    DG R   NR+   +G H
Sbjct: 690 --------SGRSGGR--------SGGRSGRQSRQGSRSGSRQDGRRRSGNRNRSRSGGH 732


>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
           sapiens]
          Length = 875

 Score =  180 bits (457), Expect = 5e-45
 Identities = 124/376 (32%), Positives = 199/376 (52%), Gaps = 29/376 (7%)

Query: 255 FAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIH 314
           F+ F   ++ +  +++++Y   T IQ Q + +AL G+D++G AKTGSGKT AF+ P+L  
Sbjct: 71  FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVL-E 129

Query: 315 IMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQ 374
            + + +    DG   +I+ PTREL  Q     ++ GK ++  +  + GG  +  +A+ + 
Sbjct: 130 ALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERI- 188

Query: 375 EGAEIVVCTPGRLIDH----VKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRP 430
               I+VCTPGRL+ H    V   AT+LQ    LV DEADR+ DMGF   + ++  ++  
Sbjct: 189 NNINILVCTPGRLLQHMDETVSFHATDLQ---MLVLDEADRILDMGFADTMNAVIENLPK 245

Query: 431 DRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVT-----------QIVEILH 479
            RQTLLFSAT  K ++ LAR  L +P  V   +  + +   T           Q + +L+
Sbjct: 246 KRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLY 305

Query: 480 SGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNK 539
           S     + L ++ + F SS   + ++ +            + G ++  LHG   Q  R +
Sbjct: 306 S--FLRSHLKKKSIVFFSSCKEVQYLYR-------VFCRLRPGVSILALHGRQQQMRRME 356

Query: 540 VISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAY 599
           V ++F +K   VL ATD+AARGLD P++  V+ +D   D +T+ HR GRT R  E G A 
Sbjct: 357 VYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEAL 416

Query: 600 TLLTPKDSNFAGDLVR 615
            +L P +      L++
Sbjct: 417 LILLPSEKAMVQQLLQ 432


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  177 bits (449), Expect = 4e-44
 Identities = 111/364 (30%), Positives = 182/364 (50%), Gaps = 25/364 (6%)

Query: 252 GSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPM 311
           G+ F  +    +L+  I +  + +P+PIQ + +P+ALSGRD++  AK G+GK+ A++ P+
Sbjct: 95  GNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPL 154

Query: 312 LIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYN-LRSVAVYGGGSMWEQA 370
           L  +  +K     D   A+++ PTREL  Q+   C +  K     + +A  GG ++ +  
Sbjct: 155 LERLDLKK-----DNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDI 209

Query: 371 KALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRP 430
             L +   +V+ TPGR++D +KK    +  V  +V DEAD++    F   +  I   +  
Sbjct: 210 MRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPK 269

Query: 431 DRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTR 490
           +RQ LL+SATF   ++K     L  P  +         E++T     L      + ++T 
Sbjct: 270 NRQILLYSATFPLSVQKFMNSHLQKPYEI------NLMEELT-----LKGVTQYYAYVTE 318

Query: 491 R--------LVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVIS 542
           R        L         ++F       E LA  + Q G++   +H  M Q  RN+V  
Sbjct: 319 RQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFH 378

Query: 543 DFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLL 602
           DF+      LV TD+  RG+DI ++  VIN+D  +  +T+ HRIGR+GR G  G+A  L+
Sbjct: 379 DFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLI 438

Query: 603 TPKD 606
           T  D
Sbjct: 439 TYDD 442


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  176 bits (447), Expect = 7e-44
 Identities = 151/543 (27%), Positives = 246/543 (45%), Gaps = 72/543 (13%)

Query: 79  EEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEEKD 138
           ++ + S VD+      NSP  ++   K   S +D  P    + + ++        +E+K 
Sbjct: 60  KKAEPSEVDM------NSPKSKKAKKKEEPSQNDISPKTKSLRKKKEP-------IEKKV 106

Query: 139 KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIID 198
              K  K  +++   E++ +A        P    +++E+E N      G     + K+ +
Sbjct: 107 VSSKTKKVTKNEEPSEEEIDA--------PKPKKMKKEKEMN------GETREKSPKLKN 152

Query: 199 PLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHF 258
             P   H E D  P E      + EI    P +                  +   +F++F
Sbjct: 153 GFP---HPEPDCNPSEAASEESNSEIEQEIPVE------------------QKEGAFSNF 191

Query: 259 GFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQ 318
              E+ +  ++    T   PIQ +      SG+D+I  A+TG+GKT +F  P++  +  +
Sbjct: 192 PISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGE 251

Query: 319 -KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGA 377
            ++ + G  P  +++ PTREL  Q+  +     K   L     YGG     Q + ++ G 
Sbjct: 252 LQDRKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACFYGGTPYGGQFERMRNGI 309

Query: 378 EIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHV-----RPDR 432
           +I+V TPGR+ DH++    +L ++ ++V DE D+M DMGF  QV  I S         + 
Sbjct: 310 DILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNP 369

Query: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRL 492
           QTLLFSAT    +  +A+  +      V   IG+  +     VE L     K +W  R  
Sbjct: 370 QTLLFSATCPHWVFNVAKKYMKSTYEQVDL-IGKKTQKTAITVEHL---AIKCHWTQRAA 425

Query: 493 V-------EFTSSGSVLLFVTKKANAEELANN--LKQEGHNLGLLHGDMDQSERNKVISD 543
           V            G  ++F   K  A+EL+ N  +KQ+  +L   HGD+ Q +R   +  
Sbjct: 426 VIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSL---HGDIPQKQREITLKG 482

Query: 544 FKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLT 603
           F+     VLVAT+VAARGLDIP +  VI     +D++++ HR GRTGRAG  GV      
Sbjct: 483 FRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQ 542

Query: 604 PKD 606
            K+
Sbjct: 543 HKE 545


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.131    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,308,089
Number of Sequences: 37866
Number of extensions: 2088244
Number of successful extensions: 10506
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 131
Number of HSP's successfully gapped in prelim test: 401
Number of HSP's that attempted gapping in prelim test: 7757
Number of HSP's gapped (non-prelim): 1796
length of query: 938
length of database: 18,247,518
effective HSP length: 112
effective length of query: 826
effective length of database: 14,006,526
effective search space: 11569390476
effective search space used: 11569390476
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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