BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] (938 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 1910 0.0 gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 1910 0.0 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 399 e-111 gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 373 e-103 gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 373 e-103 gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 362 e-100 gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 294 2e-79 gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 285 2e-76 gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 278 1e-74 gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 277 3e-74 gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 268 1e-71 gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 268 1e-71 gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 268 1e-71 gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 261 2e-69 gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 252 1e-66 gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 252 1e-66 gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 239 9e-63 gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 224 3e-58 gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 211 3e-54 gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 202 2e-51 gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 202 2e-51 gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 199 1e-50 gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 193 7e-49 gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 187 3e-47 gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 183 7e-46 gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 183 7e-46 gi|13129006 nucleolar protein GU2 [Homo sapiens] 181 3e-45 gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 180 5e-45 gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 177 4e-44 gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 176 7e-44 >gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] Length = 938 Score = 1910 bits (4948), Expect = 0.0 Identities = 938/938 (100%), Positives = 938/938 (100%) Query: 1 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 60 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY Sbjct: 1 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 60 Query: 61 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 120 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM Sbjct: 61 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 120 Query: 121 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 180 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN Sbjct: 121 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 180 Query: 181 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 240 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN Sbjct: 181 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 240 Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG Sbjct: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300 Query: 301 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV Sbjct: 301 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360 Query: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 420 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ Sbjct: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 420 Query: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS Sbjct: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480 Query: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV Sbjct: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540 Query: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT Sbjct: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600 Query: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 660 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY Sbjct: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 660 Query: 661 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 720 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK Sbjct: 661 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 720 Query: 721 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 780 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP Sbjct: 721 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 780 Query: 781 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 840 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH Sbjct: 781 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 840 Query: 841 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 900 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM Sbjct: 841 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 900 Query: 901 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 938 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS Sbjct: 901 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 938 >gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] Length = 938 Score = 1910 bits (4948), Expect = 0.0 Identities = 938/938 (100%), Positives = 938/938 (100%) Query: 1 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 60 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY Sbjct: 1 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 60 Query: 61 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 120 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM Sbjct: 61 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 120 Query: 121 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 180 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN Sbjct: 121 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 180 Query: 181 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 240 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN Sbjct: 181 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 240 Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG Sbjct: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300 Query: 301 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV Sbjct: 301 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360 Query: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 420 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ Sbjct: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 420 Query: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS Sbjct: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480 Query: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV Sbjct: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540 Query: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT Sbjct: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600 Query: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 660 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY Sbjct: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 660 Query: 661 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 720 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK Sbjct: 661 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 720 Query: 721 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 780 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP Sbjct: 721 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 780 Query: 781 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 840 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH Sbjct: 781 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 840 Query: 841 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 900 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM Sbjct: 841 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 900 Query: 901 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 938 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS Sbjct: 901 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 938 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 399 bits (1024), Expect = e-111 Identities = 235/603 (38%), Positives = 347/603 (57%), Gaps = 42/603 (6%) Query: 77 EDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEE 136 ED+++D + PAE + + +D PL+A+M EV+++ + R + Sbjct: 201 EDDDDDEDD------PAEAEKEGNEMEGEELD------PLDAYMEEVKEEVKKFNMRSVK 248 Query: 137 KD--KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPI---- 190 E+K+ + + ++A + + G + E ++D +EY S+ + Sbjct: 249 GGGGNEKKSGPTVTKVVTVVTTKKAV---VDSDKKKGELMENDQDAMEYSSEEEEVDLQT 305 Query: 191 ------APTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN-LRV 243 +K+++P +DH +I+Y PF KNFY E E+ ++ +++ R ++ + V Sbjct: 306 ALTGYQTKQRKLLEP---VDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITV 362 Query: 244 SGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGK 303 G P+P S+ G ++++ ++K Y +PTPIQ Q +P +SGRD+IGIAKTGSGK Sbjct: 363 KGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGK 422 Query: 304 TAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGG 363 T AF+ PM HIMDQ+ LE G+GPIAVI+ PTREL QI ECK+F K LR V VYGG Sbjct: 423 TIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGG 482 Query: 364 GSMWEQAKALQEGAEIVVCTPGRLIDHV---KKKATNLQRVSYLVFDEADRMFDMGFEYQ 420 + EQ L+ GAEI+VCTPGR+ID + + TNL+RV+Y+V DEADRMFDMGFE Q Sbjct: 483 TGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQ 542 Query: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480 V I +VRPDRQT++FSATF + +E LAR IL PI V G DV Q V ++ Sbjct: 543 VMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEE 602 Query: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540 K+ L L + SGSV++FV K+ +A+ L +L + + LHG +DQ +R+ + Sbjct: 603 -EKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSI 661 Query: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600 I+DFK +LVAT VAARGLD+ + V+NY + + HR GRTGRAG KG AYT Sbjct: 662 INDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYT 721 Query: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAW--FRKSRFKGGKGKKLNIGGGGL 658 +T + +AGD+++ LE + V +L + W F+ + GK K + G G Sbjct: 722 FITEDQARYAGDIIKALELSGTAVPPDL-----EKLWSDFKDQQKAEGKIIKKSSGFSGK 776 Query: 659 GYR 661 G++ Sbjct: 777 GFK 779 Score = 31.6 bits (70), Expect = 3.6 Identities = 35/139 (25%), Positives = 47/139 (33%), Gaps = 16/139 (11%) Query: 797 REGTGGSNGKRERYTE------NRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESS 850 R + G +G R R RG R S +R + R D R R Sbjct: 11 RSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRR 70 Query: 851 SRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKMEPKVDS---- 906 SR + R E R S R +R + GR S N+ K E + K + Sbjct: 71 SRSRERDRSRERRRSRSRDRR-RSRSRSRGRRSRSSSPG-NKSKKTENRSRSKEKTDGGE 128 Query: 907 ----SKMDKVDSKTDKTAD 921 K DK D + +K D Sbjct: 129 SSKEKKKDKDDKEDEKEKD 147 >gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] Length = 731 Score = 373 bits (957), Expect = e-103 Identities = 224/620 (36%), Positives = 339/620 (54%), Gaps = 42/620 (6%) Query: 174 QEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDY---PPFEKNFYNEHEEITNLTPQ 230 ++ + D + + G P KK +P + + D P FEKNFY EH E+ LTP Sbjct: 88 RDRDRDRGGFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPY 147 Query: 231 QLIDLRHKLNLRVSGA-APPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALS 289 ++ +LR K + V G P+P +F H F + +M + +T+PTPIQCQG P+ALS Sbjct: 148 EVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALS 207 Query: 290 GRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRF 349 GRDM+GIA+TGSGKT A++ P ++HI Q LE GDGPI +++ PTREL QQ+ + Sbjct: 208 GRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDY 267 Query: 350 GKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEA 409 GK L+S +YGG Q + L+ G EI + TPGRLID ++ TNL+R +YLV DEA Sbjct: 268 GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEA 327 Query: 410 DRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIG-EAN 468 DRM DMGFE Q+R I +RPDRQTL++SAT+ K++ +LA D L D ++ G++ AN Sbjct: 328 DRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSAN 387 Query: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFVTKKANAEELANNLKQEGHNLG 526 ++ QIV++ K + L + + E + ++FV K ++L ++++G Sbjct: 388 HNILQIVDVCMES-EKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAM 446 Query: 527 LLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRI 586 +HGD Q ER+ V+++F+ P+L+ATDVA+RGLD+ +K VINYD + + HRI Sbjct: 447 CIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRI 506 Query: 587 GRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646 GRT R+ KG AYT TP + A +L++ LE ANQ ++ +L+ L R GG Sbjct: 507 GRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLV-------DHRGGGG 559 Query: 647 KGKKLNIGGGGLGYRERPGLGSENM---DRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAF 703 G K GG YR + N+ D + + + + + + DR +A + Sbjct: 560 GGGK----GGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGY 615 Query: 704 ---------QSQYKSHFVAASLSNQKAGSSAAGASGWTS----AGSLNSVPTNSAQQGHN 750 S + + + G++A G S +T+ AG+ + T S G + Sbjct: 616 ANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTTST--GRS 673 Query: 751 SPDSPVTSAAKGIPGFGNTG 770 S S+++ G G +G Sbjct: 674 S-----QSSSQQFSGIGRSG 688 >gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] Length = 729 Score = 373 bits (957), Expect = e-103 Identities = 223/620 (35%), Positives = 338/620 (54%), Gaps = 44/620 (7%) Query: 174 QEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDY---PPFEKNFYNEHEEITNLTPQ 230 ++ + D + + G P KK +P + + D P FEKNFY EH E+ LTP Sbjct: 88 RDRDRDRGGFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPY 147 Query: 231 QLIDLRHKLNLRVSGA-APPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALS 289 ++ +LR K + V G P+P +F H F + +M + +T+PTPIQCQG P+ALS Sbjct: 148 EVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALS 207 Query: 290 GRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRF 349 GRDM+GIA+TGSGKT A++ P ++HI Q LE GDGPI +++ PTREL QQ+ + Sbjct: 208 GRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDY 267 Query: 350 GKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEA 409 GK L+S +YGG Q + L+ G EI + TPGRLID ++ TNL+R +YLV DEA Sbjct: 268 GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEA 327 Query: 410 DRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIG-EAN 468 DRM DMGFE Q+R I +RPDRQTL++SAT+ K++ +LA D L D ++ G++ AN Sbjct: 328 DRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSAN 387 Query: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFVTKKANAEELANNLKQEGHNLG 526 ++ QIV++ K + L + + E + ++FV K ++L ++++G Sbjct: 388 HNILQIVDVCMES-EKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAM 446 Query: 527 LLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRI 586 +HGD Q ER+ V+++F+ P+L+ATDVA+RGLD+ +K VINYD + + HRI Sbjct: 447 CIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRI 506 Query: 587 GRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646 GRT R+ KG AYT TP + A +L++ LE ANQ ++ +L+ L GG Sbjct: 507 GRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRG--------GG 558 Query: 647 KGKKLNIGGGGLGYRERPGLGSENM---DRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAF 703 G GGG YR + N+ D + + + + + + DR +A + Sbjct: 559 GG-----GGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGY 613 Query: 704 ---------QSQYKSHFVAASLSNQKAGSSAAGASGWTS----AGSLNSVPTNSAQQGHN 750 S + + + G++A G S +T+ AG+ + T S G + Sbjct: 614 ANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTTST--GRS 671 Query: 751 SPDSPVTSAAKGIPGFGNTG 770 S S+++ G G +G Sbjct: 672 S-----QSSSQQFSGIGRSG 686 >gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] Length = 614 Score = 362 bits (929), Expect = e-100 Identities = 213/552 (38%), Positives = 311/552 (56%), Gaps = 37/552 (6%) Query: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQI 268 + P FEKNFY EH ++ T Q++ R + V G P+P +F F +M I Sbjct: 50 ELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVI 109 Query: 269 RKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPI 328 + +T+PT IQ QG PVALSG DM+G+A+TGSGKT +++ P ++HI Q LE GDGPI Sbjct: 110 ARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPI 169 Query: 329 AVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLI 388 +++ PTREL QQ+ + +A L+S +YGG Q + L+ G EI + TPGRLI Sbjct: 170 CLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLI 229 Query: 389 DHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKL 448 D ++ TNL+R +YLV DEADRM DMGFE Q+R I +RPDRQTL++SAT+ K++ +L Sbjct: 230 DFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQL 289 Query: 449 ARDILIDPIRVVQGDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFV 505 A D L D I + G + AN ++ QIV++ H K L R + E S ++FV Sbjct: 290 AEDFLKDYIHINIGALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFV 348 Query: 506 TKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIP 565 K +EL ++++G +HGD Q ER+ V+++FK P+L+ATDVA+RGLD+ Sbjct: 349 ETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVE 408 Query: 566 SIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVS 625 +K VINYD + + HRIGRT R+ + G AYT TP + DL+ L ANQ ++ Sbjct: 409 DVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAIN 468 Query: 626 KELLDLAMQNAWFRKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVM 679 +LL L +++ +SR +GG + + + G GG +R+R EN DRG ++++ Sbjct: 469 PKLLQL-VEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLL 522 Query: 680 SNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNS 739 K G + AA+ +N GS+ A TS + N Sbjct: 523 KRDFGAKTQNGV-------------------YSAANYTNGSFGSNFVSAGIQTSFRTGN- 562 Query: 740 VPTNSAQQGHNS 751 PT + Q G++S Sbjct: 563 -PTGTYQNGYDS 573 >gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sapiens] Length = 648 Score = 294 bits (753), Expect = 2e-79 Identities = 169/452 (37%), Positives = 262/452 (57%), Gaps = 20/452 (4%) Query: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVS------GAAPPRPGSSFAH---FG 259 D PP +KNFY E + ++ + D K N ++ G P P + F Sbjct: 190 DLPPIKKNFYKESTATSAMSKVEA-DSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQ 248 Query: 260 FDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK 319 ++M I+K+ + +PTPIQ Q P+ L G D+IG+A+TG+GKT ++ P IH++ Q Sbjct: 249 CYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQP 308 Query: 320 ELE-PGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAE 378 L+ + P +++ PTREL Q+ EC ++ LRSV VYGGG+ EQ + L++G + Sbjct: 309 SLKGQRNRPGMLVLTPTRELALQVEGECCKYSYK-GLRSVCVYGGGNRDEQIEELKKGVD 367 Query: 379 IVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFS 438 I++ TPGRL D NL+ ++YLV DEAD+M DMGFE Q+ I VRPDRQT++ S Sbjct: 368 IIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTS 427 Query: 439 ATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSS 498 AT+ + +LA+ L +P+ V G + + I+ + KW+ + L +S+ Sbjct: 428 ATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSST 487 Query: 499 GSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558 V++FV++KA A+ L+++L ++ LHGD +Q +R K + +FK + +L+ATD+A Sbjct: 488 DKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLA 547 Query: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLE 618 +RGLD+ + V N+D R+I+ + HRIGRTGRAG GV+ T LT D A +L+ LE Sbjct: 548 SRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILE 607 Query: 619 GANQHVSKELLDLAMQNAWFRKSRFKGGKGKK 650 ANQ + +EL+ +A RFK + K+ Sbjct: 608 RANQSIPEELVSMA--------ERFKAHQQKR 631 >gi|21071032 DEAD-box protein abstrakt [Homo sapiens] Length = 622 Score = 285 bits (728), Expect = 2e-76 Identities = 214/622 (34%), Positives = 308/622 (49%), Gaps = 64/622 (10%) Query: 65 KRANFDEENAY-FEDEEEDSSNVD-LPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAE 122 KRA DE A E ED + D +PY+P RQ K + AE Sbjct: 9 KRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQR--RQLLLQKLLQRRRKG------AAE 60 Query: 123 VEDQAARDMKRLEEKD---KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQE---E 176 E Q + R +E D + NV + DQ + + AE ++ E Sbjct: 61 EEQQDSGSEPRGDEDDIPLGPQSNVSLL--------DQHQHLKEKAEARKESAKEKQLKE 112 Query: 177 EEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLR 236 EE LE ++G + K++ I Y K + + +++ ++ +R Sbjct: 113 EEKILESVAEGRALMSVKEMA--------KGITYDDPIKTSWTPPRYVLSMSEERHERVR 164 Query: 237 HKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGI 296 K ++ V G P P SF F ++ ++K PTPIQ QG+P LSGRDMIGI Sbjct: 165 KKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGI 224 Query: 297 AKTGSGKTAAFIWPMLIHIMDQKELEP---GDGPIAVIVCPTRELCQQIHAECKRFGKAY 353 A TGSGKT F P+++ ++Q++ P +GP +I+CP+REL +Q H + + + Sbjct: 225 AFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLL 284 Query: 354 N------LRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFD 407 LR GG S+ EQ + ++ G ++V TPGRL+D ++KK +L YL D Sbjct: 285 QEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALD 344 Query: 408 EADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEA 467 EADRM DMGFE +R+I S+ + RQTLLFSAT KKI+ A+ L+ P+ + G G A Sbjct: 345 EADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAA 404 Query: 468 NEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGL 527 + DV Q VE + +K +L L + + VL+F KKA+ + + L +G Sbjct: 405 SLDVIQEVEYVKE-EAKMVYLLECLQK--TPPPVLIFAEKKADVDAIHEYLLLKGVEAVA 461 Query: 528 LHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIG 587 +HG DQ ER K I F++ VLVATDVA++GLD P+I+ VINYD+ +I+ + HRIG Sbjct: 462 IHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIG 521 Query: 588 RTGRAGEKGVAYTLLTPK-DSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646 RTGR+G G+A T + D + DL L A Q V L L G Sbjct: 522 RTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHC------------G 569 Query: 647 KGKKLNIGG-------GGLGYR 661 L+IGG GGLG+R Sbjct: 570 DESMLDIGGERGCAFCGGLGHR 591 >gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapiens] Length = 631 Score = 278 bits (712), Expect = 1e-74 Identities = 163/453 (35%), Positives = 265/453 (58%), Gaps = 14/453 (3%) Query: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRV------SGAAP--PRPGSSFAH-FG 259 D PP +KNFY E + + ++ Q+I+ R K N + SG P+P F F Sbjct: 170 DLPPVKKNFYIESKATSCMSEMQVINWR-KENFNITCDDLKSGEKRLIPKPTCRFKDAFQ 228 Query: 260 FDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK 319 L+ I + +PTPIQ Q P+ L G D+I +A+TG+GKT +++ P IH+ Q Sbjct: 229 QYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQP 288 Query: 320 -ELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAE 378 E +GP +++ PTREL + AEC ++ L+S+ +YGG + Q + + +G + Sbjct: 289 ISREQRNGPGMLVLTPTRELALHVEAECSKYSYK-GLKSICIYGGRNRNGQIEDISKGVD 347 Query: 379 IVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFS 438 I++ TPGRL D + NL+ ++YLV DEAD+M DM FE Q+R I VRPDRQT++ S Sbjct: 348 IIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTS 407 Query: 439 ATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTS- 497 AT+ + +LA L DP+ V G++ + + I+ + K LT+ VE S Sbjct: 408 ATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEK-RALTQEFVENMSP 466 Query: 498 SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDV 557 + V++FV++K A++L+++ +G + LHG+ +QS++ + + DFK +I +L+ TD+ Sbjct: 467 NDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526 Query: 558 AARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNL 617 +RGLD+ + V NYD R+ID + HR+G GR G+ G + TL+T +DS AG+L++ L Sbjct: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586 Query: 618 EGANQHVSKELLDLAMQNAWFRKSRFKGGKGKK 650 + ANQ V ++L+ +A Q ++ R + + +K Sbjct: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRK 619 >gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapiens] Length = 820 Score = 277 bits (709), Expect = 3e-74 Identities = 162/416 (38%), Positives = 234/416 (56%), Gaps = 32/416 (7%) Query: 222 EEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQC 281 +++ +T + R ++ G P P S+ ++ I K Y +PTPIQ Sbjct: 360 KKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQR 419 Query: 282 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKEL----EPGDGPIAVIVCPTRE 337 Q +P+ L RD+IG+A+TGSGKTAAF+ P+L+ I ++ E GP A+I+ PTRE Sbjct: 420 QAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRE 479 Query: 338 LCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATN 397 L QQI E +FGK +R+VAV GG S +Q L+ G EIV+ TPGRLID ++ + Sbjct: 480 LAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLV 539 Query: 398 LQRVSYLVFDEADRMFDMGFEYQVRSIASHV-----RPD--------------------- 431 L R +Y+V DEADRM DMGFE V+ I H+ +PD Sbjct: 540 LSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKY 599 Query: 432 RQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRR 491 RQT++F+AT +E+LAR L P V G G+ +E V Q V ++ + L Sbjct: 600 RQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLA-- 657 Query: 492 LVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPV 551 ++E +++FV +K + LA +L++ G+N LHG Q +R +S+ K + Sbjct: 658 ILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDI 717 Query: 552 LVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDS 607 LVATDVA RG+DI + V+NYD+A++I+ + HRIGRTGRAG+ GVA T LT +DS Sbjct: 718 LVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDS 773 Score = 36.6 bits (83), Expect = 0.11 Identities = 23/110 (20%), Positives = 48/110 (43%), Gaps = 2/110 (1%) Query: 794 NNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPR-HGDGGRHGDGYRHPESSSR 852 + R+ + + KR R + R S + ++ ++ R H + R + R+ + R Sbjct: 33 DRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERERDKERDRNKKDRDR 92 Query: 853 HTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKMEP 902 DGHR ++R S G + ++ +S+K+ + +PK +P Sbjct: 93 DKDGHRRDKDRKRSSLS-PGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQP 141 >gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo sapiens] Length = 662 Score = 268 bits (686), Expect = 1e-71 Identities = 161/437 (36%), Positives = 238/437 (54%), Gaps = 25/437 (5%) Query: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313 SF+ E +M I + YT+PTP+Q +P+ RD++ A+TGSGKTAAF+ P+L Sbjct: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240 Query: 314 HIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHAECKRFGKAYNLRS 357 I PG+ PI++++ PTREL QI+ E ++F +R Sbjct: 241 QIYSDG---PGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRP 297 Query: 358 VAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGF 417 VYGG + +Q + L+ G ++V TPGRL+D +++ L YLV DEADRM DMGF Sbjct: 298 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 357 Query: 418 EYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQ 473 E Q+R I + R T++FSATF K+I+ LARD L + I + G +G +E++TQ Sbjct: 358 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 417 Query: 474 IVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMD 533 V + K ++L L L+FV K A+ L + L EG+ +HGD Sbjct: 418 KVVWVEES-DKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRS 476 Query: 534 QSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAG 593 Q +R + + F+ P+LVAT VAARGLDI ++K VIN+D+ DI+ + HRIGRTGR G Sbjct: 477 QRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 536 Query: 594 EKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNI 653 G+A + ++ N DL+ L A Q V L ++A ++ + SR + K + + Sbjct: 537 NLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGR-SKSSRFSG 595 Query: 654 GGGGLGYRERPGLGSEN 670 G G YR+ G S + Sbjct: 596 GFGARDYRQSSGASSSS 612 >gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo sapiens] Length = 660 Score = 268 bits (686), Expect = 1e-71 Identities = 165/459 (35%), Positives = 248/459 (54%), Gaps = 27/459 (5%) Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300 + +G+ P +F+ E +M I + YT+PTP+Q +P+ RD++ A+TG Sbjct: 166 VEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTG 225 Query: 301 SGKTAAFIWPMLIHIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHA 344 SGKTAAF+ P+L I PG+ PI++++ PTREL QI+ Sbjct: 226 SGKTAAFLLPILSQIYTDG---PGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYE 282 Query: 345 ECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYL 404 E ++F +R VYGG + +Q + L+ G ++V TPGRL+D +++ L YL Sbjct: 283 EARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYL 342 Query: 405 VFDEADRMFDMGFEYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVV 460 V DEADRM DMGFE Q+R I + R T++FSATF K+I+ LARD L + I + Sbjct: 343 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLA 402 Query: 461 QGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ 520 G +G +E++TQ V + K ++L L S L+FV K A+ L + L Sbjct: 403 VGRVGSTSENITQKV-VWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYH 461 Query: 521 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID 580 EG+ +HGD Q +R + + F+ P+LVAT VAARGLDI +++ VIN+D+ DI+ Sbjct: 462 EGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIE 521 Query: 581 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK 640 + HRIGRTGR G G+A + K+ N DL+ L A Q V L ++A ++ + Sbjct: 522 EYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGG 581 Query: 641 SRFKGGKGKKLNIGGGGLGYRERPGLGSENM--DRGNNN 677 SR + K + + G G YR+ G S RG+++ Sbjct: 582 SRGR-SKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSS 619 >gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo sapiens] Length = 660 Score = 268 bits (686), Expect = 1e-71 Identities = 165/459 (35%), Positives = 248/459 (54%), Gaps = 27/459 (5%) Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300 + +G+ P +F+ E +M I + YT+PTP+Q +P+ RD++ A+TG Sbjct: 166 VEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTG 225 Query: 301 SGKTAAFIWPMLIHIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHA 344 SGKTAAF+ P+L I PG+ PI++++ PTREL QI+ Sbjct: 226 SGKTAAFLLPILSQIYTDG---PGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYE 282 Query: 345 ECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYL 404 E ++F +R VYGG + +Q + L+ G ++V TPGRL+D +++ L YL Sbjct: 283 EARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYL 342 Query: 405 VFDEADRMFDMGFEYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVV 460 V DEADRM DMGFE Q+R I + R T++FSATF K+I+ LARD L + I + Sbjct: 343 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLA 402 Query: 461 QGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ 520 G +G +E++TQ V + K ++L L S L+FV K A+ L + L Sbjct: 403 VGRVGSTSENITQKV-VWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYH 461 Query: 521 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID 580 EG+ +HGD Q +R + + F+ P+LVAT VAARGLDI +++ VIN+D+ DI+ Sbjct: 462 EGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIE 521 Query: 581 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK 640 + HRIGRTGR G G+A + K+ N DL+ L A Q V L ++A ++ + Sbjct: 522 EYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGG 581 Query: 641 SRFKGGKGKKLNIGGGGLGYRERPGLGSENM--DRGNNN 677 SR + K + + G G YR+ G S RG+++ Sbjct: 582 SRGR-SKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSS 619 >gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 [Homo sapiens] Length = 690 Score = 261 bits (667), Expect = 2e-69 Identities = 206/660 (31%), Positives = 313/660 (47%), Gaps = 99/660 (15%) Query: 7 GPGTKRGFGFGGFAISA--GKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFYKIGS 64 GP + F GFA G ++ + ++ + TS+ GFG +G Sbjct: 47 GPSRRDHFMKSGFASGRNFGNRDAGECNKRDN-----TSTMGGFG------------VGK 89 Query: 65 KRANFDEENAYFEDEEE-----DSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDD----- 114 N N+ FED + +SSN E++PTR + SK D+D D D Sbjct: 90 SFGNRGFSNSRFEDGDSSGFWRESSN------DCEDNPTRNRGFSKRGDNDLDPDECMQR 143 Query: 115 ---------PLEAFMAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMA 165 P+ + + +R ER KG+ +++ + ++ Sbjct: 144 TGGLFGSRRPVLSGTGNGDTSQSRS-----GSGSERGGYKGLNEEVITGSGKNSW----- 193 Query: 166 ENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEIT 225 + E E D+ G P I P PP D E + + ++ Sbjct: 194 --------KSEAEGGESSDTQG----PKVTYIPPPPPED---------EDSIFAHYQTGI 232 Query: 226 NLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVP 285 N D + + VSG P +F + L + I K+ YT+ TP+Q +P Sbjct: 233 NF------DKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIP 286 Query: 286 VALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQ-------KELEPGDGPIAVIVCPTREL 338 + L+GRD++ A+TGSGKTAAF+ P+L H+M KEL+ P +IV PTREL Sbjct: 287 IILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE---PECIIVAPTREL 343 Query: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNL 398 QI+ E ++F +R+V +YGG + + + +G I+ TPGRL+D + K+ L Sbjct: 344 VNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGL 403 Query: 399 QRVSYLVFDEADRMFDMGFEYQVRSIAS----HVRPDRQTLLFSATFRKKIEKLARDIL- 453 +++ YLV DEADRM DMGF +++ + S + RQTL+FSATF ++I++LA + L Sbjct: 404 KQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLK 463 Query: 454 IDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEE 513 + + V G +G A DV Q V L G ++ ++FV K A+ Sbjct: 464 SNYLFVAVGQVGGACRDVQQTV--LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADF 521 Query: 514 LANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINY 573 +A L QE + +HGD +Q ER + + DF+ PVLVAT VAARGLDI +++ VIN+ Sbjct: 522 IATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINF 581 Query: 574 DVARDIDTHTHRIGRTGRAGEKGVAYTLL-TPKDSNFAGDLVRNLEGANQHVSKELLDLA 632 D+ ID + HRIGRTGR G G A + D++ A LV+ L A Q V L ++A Sbjct: 582 DLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 641 >gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 [Homo sapiens] Length = 724 Score = 252 bits (644), Expect = 1e-66 Identities = 156/405 (38%), Positives = 229/405 (56%), Gaps = 18/405 (4%) Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300 + VSG P +F + L + I K+ YT+ TP+Q +P+ L+GRD++ A+TG Sbjct: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335 Query: 301 SGKTAAFIWPMLIHIMDQ-------KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAY 353 SGKTAAF+ P+L H+M KEL+ P +IV PTREL QI+ E ++F Sbjct: 336 SGKTAAFLLPILAHMMHDGITASRFKELQE---PECIIVAPTRELVNQIYLEARKFSFGT 392 Query: 354 NLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMF 413 +R+V +YGG + + + +G I+ TPGRL+D + K+ L+++ YLV DEADRM Sbjct: 393 CVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452 Query: 414 DMGFEYQVRSIAS----HVRPDRQTLLFSATFRKKIEKLARDIL-IDPIRVVQGDIGEAN 468 DMGF +++ + S + RQTL+FSATF ++I++LA + L + + V G +G A Sbjct: 453 DMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGAC 512 Query: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLL 528 DV Q V L G ++ ++FV K A+ +A L QE + + Sbjct: 513 RDVQQTV--LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSI 570 Query: 529 HGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGR 588 HGD +Q ER + + DF+ PVLVAT VAARGLDI +++ VIN+D+ ID + HRIGR Sbjct: 571 HGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGR 630 Query: 589 TGRAGEKGVAYTLL-TPKDSNFAGDLVRNLEGANQHVSKELLDLA 632 TGR G G A + D++ A LV+ L A Q V L ++A Sbjct: 631 TGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 675 >gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [Homo sapiens] Length = 724 Score = 252 bits (644), Expect = 1e-66 Identities = 156/405 (38%), Positives = 229/405 (56%), Gaps = 18/405 (4%) Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300 + VSG P +F + L + I K+ YT+ TP+Q +P+ L+GRD++ A+TG Sbjct: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335 Query: 301 SGKTAAFIWPMLIHIMDQ-------KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAY 353 SGKTAAF+ P+L H+M KEL+ P +IV PTREL QI+ E ++F Sbjct: 336 SGKTAAFLLPILAHMMHDGITASRFKELQE---PECIIVAPTRELVNQIYLEARKFSFGT 392 Query: 354 NLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMF 413 +R+V +YGG + + + +G I+ TPGRL+D + K+ L+++ YLV DEADRM Sbjct: 393 CVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452 Query: 414 DMGFEYQVRSIAS----HVRPDRQTLLFSATFRKKIEKLARDIL-IDPIRVVQGDIGEAN 468 DMGF +++ + S + RQTL+FSATF ++I++LA + L + + V G +G A Sbjct: 453 DMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGAC 512 Query: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLL 528 DV Q V L G ++ ++FV K A+ +A L QE + + Sbjct: 513 RDVQQTV--LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSI 570 Query: 529 HGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGR 588 HGD +Q ER + + DF+ PVLVAT VAARGLDI +++ VIN+D+ ID + HRIGR Sbjct: 571 HGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGR 630 Query: 589 TGRAGEKGVAYTLL-TPKDSNFAGDLVRNLEGANQHVSKELLDLA 632 TGR G G A + D++ A LV+ L A Q V L ++A Sbjct: 631 TGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 675 >gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sapiens] Length = 619 Score = 239 bits (610), Expect = 9e-63 Identities = 152/460 (33%), Positives = 240/460 (52%), Gaps = 17/460 (3%) Query: 206 SEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLM 265 SE + P Y EH I NL Q+ +L+ +L + V G RP F H E L Sbjct: 156 SEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN 215 Query: 266 HQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGD 325 H ++KS Y PTPIQ Q +PV L GRD++ A TGSGKTAAF+ P+++ + + + Sbjct: 216 HNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESKT---- 271 Query: 326 GPIAVIVCPTRELCQQIHAECKRFGKAY-NLRSVAVYGGGSMWEQAKALQEGAEIVVCTP 384 P A+I+ PTREL QI + K +++V + GG + Q LQ+ ++++ TP Sbjct: 272 -PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATP 330 Query: 385 GRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKK 444 GRL+D +K+ + L V +V DEAD M MGF+ QV I ++ D QT+L SAT Sbjct: 331 GRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTS 390 Query: 445 IEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGS---- 500 IE+LA +L +P+R++ G+ +V QI+ + P+K ++L E + Sbjct: 391 IEQLASQLLHNPVRIITGEKNLPCANVRQII-LWVEDPAK----KKKLFEILNDKKLFKP 445 Query: 501 -VLLFVTKKANAEELANNL-KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558 VL+FV K A+ L+ + K G +H + Q ER ++ + D V+V+T V Sbjct: 446 PVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVL 505 Query: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLE 618 RGLD+ S++ V+N+D+ +D + H+IGR GR G+ G A T + D+ + ++ Sbjct: 506 GRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVK 565 Query: 619 GANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGL 658 + +LL+ + RK + K + + + G L Sbjct: 566 PTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLVTGANL 605 >gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 [Homo sapiens] Length = 455 Score = 224 bits (571), Expect = 3e-58 Identities = 136/356 (38%), Positives = 200/356 (56%), Gaps = 12/356 (3%) Query: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313 +F G + L + +T+PT IQ + +P+AL GRD+IG+A+TGSGKT AF P+L Sbjct: 25 TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84 Query: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373 + LE A+++ PTREL QI + + G + ++S + GG Q+ AL Sbjct: 85 AL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL 139 Query: 374 QEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR 432 + I++ TPGRLIDH++ K NL+ + YLV DEADR+ +M FE +V I + DR Sbjct: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199 Query: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWN--WLTR 490 +T LFSAT KK++KL R L +P++ + E + Q + PSK+ +L Sbjct: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI---PSKFKDTYLVY 256 Query: 491 RLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIP 550 L E + S ++F + N + A L+ G LHG M QS+R ++ FK K Sbjct: 257 ILNELAGN-SFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARS 315 Query: 551 VLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606 +L+ATDVA+RGLDIP + V+N+D+ + HR+GRT RAG G A T +T D Sbjct: 316 ILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYD 371 >gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sapiens] Length = 796 Score = 211 bits (536), Expect = 3e-54 Identities = 150/501 (29%), Positives = 248/501 (49%), Gaps = 45/501 (8%) Query: 123 VEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLE 182 ++++ + K+ + +DKE K+ K +E+E + + G +E+ED E Sbjct: 117 LDEKIEKVRKKRKTEDKEAKSGK-----LEKEKEAKE-----------GSEPKEQEDLQE 160 Query: 183 YDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLR 242 D +G+ + SE DY ++N + + + ++ + Sbjct: 161 NDEEGSED-------------EASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGF 207 Query: 243 VSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSG 302 A+ SF L+ I + QPTPIQ +PV L G+D+ A TG+G Sbjct: 208 FEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTG 267 Query: 303 KTAAFIWPMLIHIMDQKELEPGDGPIA--VIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360 KTAAF P+L ++ +P P+ +++ PTREL Q+H+ ++ + N+ + Sbjct: 268 KTAAFALPVLERLI----YKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLA 323 Query: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEY 419 GG + Q AL+ +I++ TPGRLIDH+ + +L + L+ DEADRM D FE Sbjct: 324 VGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEE 383 Query: 420 QVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIV--EI 477 Q++ I RQT+LFSAT +++ LA L +P+R+ +N DV + E Sbjct: 384 QMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVN----SNTDVAPFLRQEF 439 Query: 478 LHSGPSKWN---WLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQ 534 + P++ + L+ T + V+LF K A + L G +G LHG++ Q Sbjct: 440 IRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQ 499 Query: 535 SERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGE 594 ++R + + FK + I +LVATDVAARGLDI +KTVIN+ + I + HR+GRT RAG Sbjct: 500 TQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGR 559 Query: 595 KGVAYTLLTPKDSNFAGDLVR 615 G + +L+ + ++V+ Sbjct: 560 AGRSVSLVGEDERKMLKEIVK 580 >gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 [Homo sapiens] Length = 881 Score = 202 bits (513), Expect = 2e-51 Identities = 124/364 (34%), Positives = 183/364 (50%), Gaps = 3/364 (0%) Query: 250 RPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIW 309 + F G + I K Y PTPIQ + +PV L G+D++ +A+TGSGKTA F+ Sbjct: 93 KKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLL 152 Query: 310 PMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ 369 PM + K G A+I+ PTREL Q K GK L++ + GG M +Q Sbjct: 153 PMFERL---KTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQ 209 Query: 370 AKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVR 429 AL E +I++ TPGRL+ + + LQ V Y+VFDEADR+F+MGF Q++ I + + Sbjct: 210 FAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLP 269 Query: 430 PDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT 489 QT+LFSAT K + + AR L +P+ + + NE + ++ L Sbjct: 270 GGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLH 329 Query: 490 RRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDI 549 ++FV K +AE L L + + ++ +D + R ++ F Sbjct: 330 LLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKC 389 Query: 550 PVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNF 609 L+ TD+AARGLDIP + VINY HR+GR RAG G AY+L+ P + + Sbjct: 390 STLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPY 449 Query: 610 AGDL 613 DL Sbjct: 450 LLDL 453 >gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1 [Homo sapiens] Length = 882 Score = 202 bits (513), Expect = 2e-51 Identities = 124/364 (34%), Positives = 183/364 (50%), Gaps = 3/364 (0%) Query: 250 RPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIW 309 + F G + I K Y PTPIQ + +PV L G+D++ +A+TGSGKTA F+ Sbjct: 93 KKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLL 152 Query: 310 PMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ 369 PM + K G A+I+ PTREL Q K GK L++ + GG M +Q Sbjct: 153 PMFERL---KTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQ 209 Query: 370 AKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVR 429 AL E +I++ TPGRL+ + + LQ V Y+VFDEADR+F+MGF Q++ I + + Sbjct: 210 FAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLP 269 Query: 430 PDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT 489 QT+LFSAT K + + AR L +P+ + + NE + ++ L Sbjct: 270 GGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLH 329 Query: 490 RRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDI 549 ++FV K +AE L L + + ++ +D + R ++ F Sbjct: 330 LLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKC 389 Query: 550 PVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNF 609 L+ TD+AARGLDIP + VINY HR+GR RAG G AY+L+ P + + Sbjct: 390 STLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPY 449 Query: 610 AGDL 613 DL Sbjct: 450 LLDL 453 >gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapiens] Length = 483 Score = 199 bits (505), Expect = 1e-50 Identities = 135/396 (34%), Positives = 203/396 (51%), Gaps = 30/396 (7%) Query: 253 SSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPML 312 + FA G L+ Q R+ QPTP+Q +P L GRD +G AKTGSGKTAAF+ P+L Sbjct: 2 AGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPIL 61 Query: 313 IHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKA 372 QK E G +++ PTREL QI + + GK L+ + GG M QA Sbjct: 62 -----QKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALE 116 Query: 373 LQEGAEIVVCTPGRLIDHVKKKAT-NLQRVSYLVFDEADRMFDMG---FEYQVRSIASHV 428 L +V+ TPGRL DH++ T +++++ +LV DEADR+ + G F + +I + V Sbjct: 117 LSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAV 176 Query: 429 RPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSG---PSKW 485 RQTLLFSAT + +L + Q EA V+ + ++ P K Sbjct: 177 PARRQTLLFSATLTDTLREL------QGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKV 230 Query: 486 N-----WLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540 L +R + S+++F + L L++ LH M Q ER Sbjct: 231 KDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAA 290 Query: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600 ++ FK +L+ATDVA+RGLDIP+++ VIN++ + HR+GRT RAG +G A T Sbjct: 291 LAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAIT 350 Query: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNA 636 L+T D + LV +E + + K+L + +++ A Sbjct: 351 LVTQYDIH----LVHAIE---EQIKKKLEEFSVEEA 379 >gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 [Homo sapiens] Length = 406 Score = 193 bits (490), Expect = 7e-49 Identities = 122/354 (34%), Positives = 180/354 (50%), Gaps = 57/354 (16%) Query: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313 +F G + L + +T+PT IQ + +P+AL GRD+IG+A+TGSGKT AF P+L Sbjct: 25 TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84 Query: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373 + LE A+++ PTREL QI + + G + ++S + GG Q+ AL Sbjct: 85 AL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL 139 Query: 374 QEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR 432 + I++ TPGRLIDH++ K NL+ + YLV DEADR+ +M FE +V I + DR Sbjct: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199 Query: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRL 492 +T LFSAT KK++KL R L +P++ + E + Q + PSK+ Sbjct: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI---PSKF------- 249 Query: 493 VEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVL 552 +S+R ++ FK K +L Sbjct: 250 -----------------------------------------KSKRLGSLNKFKAKARSIL 268 Query: 553 VATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606 +ATDVA+RGLDIP + V+N+D+ + HR+GRT RAG G A T +T D Sbjct: 269 LATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYD 322 >gi|7661920 eukaryotic translation initiation factor 4A, isoform 3 [Homo sapiens] Length = 411 Score = 187 bits (476), Expect = 3e-47 Identities = 116/383 (30%), Positives = 195/383 (50%), Gaps = 13/383 (3%) Query: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313 +F G E L+ I + +P+ IQ + + + GRD+I +++G+GKTA F +L Sbjct: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVL- 97 Query: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373 +D + E A+I+ PTREL QI G N++ A GG ++ E + L Sbjct: 98 QCLDIQVRETQ----ALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKL 153 Query: 374 QEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQ 433 G +V TPGR+ D +++++ + + LV DEAD M + GF+ Q+ + ++ P Q Sbjct: 154 DYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQ 213 Query: 434 TLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLV 493 +L SAT +I ++ + DPIR++ E + Q + K++ L Sbjct: 214 VVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYD 273 Query: 494 EFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLV 553 T + +V+ F K + L +++ + +HGDM Q ER ++ +F+ VL+ Sbjct: 274 TLTITQAVI-FCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLI 332 Query: 554 ATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDL 613 +TDV ARGLD+P + +INYD+ + + + HRIGR+GR G KGVA + D Sbjct: 333 STDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDD------- 385 Query: 614 VRNLEGANQHVSKELLDLAMQNA 636 +R L Q+ S ++ ++ M A Sbjct: 386 IRILRDIEQYYSTQIDEMPMNVA 408 >gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapiens] Length = 491 Score = 183 bits (464), Expect = 7e-46 Identities = 134/396 (33%), Positives = 202/396 (51%), Gaps = 18/396 (4%) Query: 223 EITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAH----FGFDEQLMHQIRKSEYTQPTP 278 ++ NL +++ LR+K + V G P P ++F + + +L+ I + + PTP Sbjct: 23 KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 82 Query: 279 IQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTREL 338 IQ Q +PV L GR+++ A TGSGKT AF P+L+ Q + G A+I+ PTREL Sbjct: 83 IQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM----QLKQPANKGFRALIISPTREL 138 Query: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ-AKALQEGAEIVVCTPGRLIDHVKKK--A 395 QIH E + + R ++ ++ + +I+V TP RLI +K+ Sbjct: 139 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPG 198 Query: 396 TNLQRVSYLVFDEADRMFD---MGFEYQVRSIASHVRPDR-QTLLFSATFRKKIEKLARD 451 +L V +LV DE+D++F+ GF Q+ SI + + +FSATF +E+ + Sbjct: 199 IDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKL 258 Query: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT-RRLVEFTSSGSVLLFVTKKAN 510 L + I V G A E V Q E+L G L R LV+ + VL+FV Sbjct: 259 NLDNVISVSIGARNSAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIER 316 Query: 511 AEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTV 570 A+EL + L EG N+ ++H + Q +R+ + F+ I VL+ T + ARG+D + V Sbjct: 317 AKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLV 376 Query: 571 INYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606 INYD + HRIGRTGRAG KG A T T D Sbjct: 377 INYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDD 412 >gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapiens] Length = 599 Score = 183 bits (464), Expect = 7e-46 Identities = 134/396 (33%), Positives = 202/396 (51%), Gaps = 18/396 (4%) Query: 223 EITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAH----FGFDEQLMHQIRKSEYTQPTP 278 ++ NL +++ LR+K + V G P P ++F + + +L+ I + + PTP Sbjct: 131 KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 190 Query: 279 IQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTREL 338 IQ Q +PV L GR+++ A TGSGKT AF P+L+ Q + G A+I+ PTREL Sbjct: 191 IQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM----QLKQPANKGFRALIISPTREL 246 Query: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ-AKALQEGAEIVVCTPGRLIDHVKKK--A 395 QIH E + + R ++ ++ + +I+V TP RLI +K+ Sbjct: 247 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPG 306 Query: 396 TNLQRVSYLVFDEADRMFD---MGFEYQVRSIASHVRPDR-QTLLFSATFRKKIEKLARD 451 +L V +LV DE+D++F+ GF Q+ SI + + +FSATF +E+ + Sbjct: 307 IDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKL 366 Query: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT-RRLVEFTSSGSVLLFVTKKAN 510 L + I V G A E V Q E+L G L R LV+ + VL+FV Sbjct: 367 NLDNVISVSIGARNSAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIER 424 Query: 511 AEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTV 570 A+EL + L EG N+ ++H + Q +R+ + F+ I VL+ T + ARG+D + V Sbjct: 425 AKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLV 484 Query: 571 INYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606 INYD + HRIGRTGRAG KG A T T D Sbjct: 485 INYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDD 520 >gi|13129006 nucleolar protein GU2 [Homo sapiens] Length = 737 Score = 181 bits (459), Expect = 3e-45 Identities = 147/505 (29%), Positives = 237/505 (46%), Gaps = 57/505 (11%) Query: 134 LEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPT 193 LEE + ++K + ++ D +++ Y ++ + E E+ + D D P A Sbjct: 17 LEESESQKK-------ERQKSDRRKSRHHYDSDEKS-----ETRENGVTDDLDA-PKAKK 63 Query: 194 KKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGS 253 K+ + L +E + F H+ P ID K + RVS S Sbjct: 64 SKMKEKLN--GDTEEGFNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKS 121 Query: 254 S----------------FAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIA 297 S F++F E+ + ++ T PIQ + G+D+I A Sbjct: 122 SDNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQA 181 Query: 298 KTGSGKTAAFIWPMLIHIM-DQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLR 356 +TG+GKT +F P++ + +Q+ ++ P +++ PTREL Q+ + K + L Sbjct: 182 RTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLS 239 Query: 357 SVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMG 416 YGG S Q ++ G +I+V TPGR+ DH++ +L ++ ++V DE D+M D+G Sbjct: 240 VACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLG 299 Query: 417 FEYQVRSIA-----SHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGD-IGEANED 470 F QV I + + QTLLFSAT + + K+A+ + R Q D +G+ + Sbjct: 300 FAEQVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKS--RYEQVDLVGKMTQK 357 Query: 471 VTQIVEILHSGPSKWNWLTRRLV-------EFTSSGSVLLFVTKKANAEELANN--LKQE 521 VE L + +W R V S G ++F K N E+A N +KQ Sbjct: 358 AATTVEHL---AIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQ- 413 Query: 522 GHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDT 581 N LHGD+ QS+R + F++ VLVAT+VAARGLDIP + VI +D+++ Sbjct: 414 --NAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVES 471 Query: 582 HTHRIGRTGRAGEKGVAYTLLTPKD 606 + HR GRTGRAG G+ P++ Sbjct: 472 YIHRSGRTGRAGRTGICICFYQPRE 496 Score = 34.7 bits (78), Expect = 0.43 Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 21/119 (17%) Query: 753 DSPVTSAAKGIPGFGNTGNISGAPVTYPSAGAQGVNNTASGNNSREGTGGSNGKRERYTE 812 D P T + + + ++ I P P NT+S NSR+ +G S+G+ R Sbjct: 635 DVPTTESERLQAEWHDSDWILSVPAKLPEIEEYYDGNTSS--NSRQRSGWSSGRSGR--- 689 Query: 813 NRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESSSRHTDGHRHGENRHGGSAGRH 871 G +G R GGR G R S DG R NR+ +G H Sbjct: 690 --------SGRSGGR--------SGGRSGRQSRQGSRSGSRQDGRRRSGNRNRSRSGGH 732 >gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapiens] Length = 875 Score = 180 bits (457), Expect = 5e-45 Identities = 124/376 (32%), Positives = 199/376 (52%), Gaps = 29/376 (7%) Query: 255 FAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIH 314 F+ F ++ + +++++Y T IQ Q + +AL G+D++G AKTGSGKT AF+ P+L Sbjct: 71 FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVL-E 129 Query: 315 IMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQ 374 + + + DG +I+ PTREL Q ++ GK ++ + + GG + +A+ + Sbjct: 130 ALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERI- 188 Query: 375 EGAEIVVCTPGRLIDH----VKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRP 430 I+VCTPGRL+ H V AT+LQ LV DEADR+ DMGF + ++ ++ Sbjct: 189 NNINILVCTPGRLLQHMDETVSFHATDLQ---MLVLDEADRILDMGFADTMNAVIENLPK 245 Query: 431 DRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVT-----------QIVEILH 479 RQTLLFSAT K ++ LAR L +P V + + + T Q + +L+ Sbjct: 246 KRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLY 305 Query: 480 SGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNK 539 S + L ++ + F SS + ++ + + G ++ LHG Q R + Sbjct: 306 S--FLRSHLKKKSIVFFSSCKEVQYLYR-------VFCRLRPGVSILALHGRQQQMRRME 356 Query: 540 VISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAY 599 V ++F +K VL ATD+AARGLD P++ V+ +D D +T+ HR GRT R E G A Sbjct: 357 VYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEAL 416 Query: 600 TLLTPKDSNFAGDLVR 615 +L P + L++ Sbjct: 417 LILLPSEKAMVQQLLQ 432 >gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapiens] Length = 483 Score = 177 bits (449), Expect = 4e-44 Identities = 111/364 (30%), Positives = 182/364 (50%), Gaps = 25/364 (6%) Query: 252 GSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPM 311 G+ F + +L+ I + + +P+PIQ + +P+ALSGRD++ AK G+GK+ A++ P+ Sbjct: 95 GNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPL 154 Query: 312 LIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYN-LRSVAVYGGGSMWEQA 370 L + +K D A+++ PTREL Q+ C + K + +A GG ++ + Sbjct: 155 LERLDLKK-----DNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDI 209 Query: 371 KALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRP 430 L + +V+ TPGR++D +KK + V +V DEAD++ F + I + Sbjct: 210 MRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPK 269 Query: 431 DRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTR 490 +RQ LL+SATF ++K L P + E++T L + ++T Sbjct: 270 NRQILLYSATFPLSVQKFMNSHLQKPYEI------NLMEELT-----LKGVTQYYAYVTE 318 Query: 491 R--------LVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVIS 542 R L ++F E LA + Q G++ +H M Q RN+V Sbjct: 319 RQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFH 378 Query: 543 DFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLL 602 DF+ LV TD+ RG+DI ++ VIN+D + +T+ HRIGR+GR G G+A L+ Sbjct: 379 DFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLI 438 Query: 603 TPKD 606 T D Sbjct: 439 TYDD 442 >gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapiens] Length = 783 Score = 176 bits (447), Expect = 7e-44 Identities = 151/543 (27%), Positives = 246/543 (45%), Gaps = 72/543 (13%) Query: 79 EEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEEKD 138 ++ + S VD+ NSP ++ K S +D P + + ++ +E+K Sbjct: 60 KKAEPSEVDM------NSPKSKKAKKKEEPSQNDISPKTKSLRKKKEP-------IEKKV 106 Query: 139 KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIID 198 K K +++ E++ +A P +++E+E N G + K+ + Sbjct: 107 VSSKTKKVTKNEEPSEEEIDA--------PKPKKMKKEKEMN------GETREKSPKLKN 152 Query: 199 PLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHF 258 P H E D P E + EI P + + +F++F Sbjct: 153 GFP---HPEPDCNPSEAASEESNSEIEQEIPVE------------------QKEGAFSNF 191 Query: 259 GFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQ 318 E+ + ++ T PIQ + SG+D+I A+TG+GKT +F P++ + + Sbjct: 192 PISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGE 251 Query: 319 -KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGA 377 ++ + G P +++ PTREL Q+ + K L YGG Q + ++ G Sbjct: 252 LQDRKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACFYGGTPYGGQFERMRNGI 309 Query: 378 EIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHV-----RPDR 432 +I+V TPGR+ DH++ +L ++ ++V DE D+M DMGF QV I S + Sbjct: 310 DILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNP 369 Query: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRL 492 QTLLFSAT + +A+ + V IG+ + VE L K +W R Sbjct: 370 QTLLFSATCPHWVFNVAKKYMKSTYEQVDL-IGKKTQKTAITVEHL---AIKCHWTQRAA 425 Query: 493 V-------EFTSSGSVLLFVTKKANAEELANN--LKQEGHNLGLLHGDMDQSERNKVISD 543 V G ++F K A+EL+ N +KQ+ +L HGD+ Q +R + Sbjct: 426 VIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSL---HGDIPQKQREITLKG 482 Query: 544 FKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLT 603 F+ VLVAT+VAARGLDIP + VI +D++++ HR GRTGRAG GV Sbjct: 483 FRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQ 542 Query: 604 PKD 606 K+ Sbjct: 543 HKE 545 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.131 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 40,308,089 Number of Sequences: 37866 Number of extensions: 2088244 Number of successful extensions: 10506 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 131 Number of HSP's successfully gapped in prelim test: 401 Number of HSP's that attempted gapping in prelim test: 7757 Number of HSP's gapped (non-prelim): 1796 length of query: 938 length of database: 18,247,518 effective HSP length: 112 effective length of query: 826 effective length of database: 14,006,526 effective search space: 11569390476 effective search space used: 11569390476 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.