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Search of human proteins with 45446743
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
(938 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 1910 0.0
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 1910 0.0
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 399 e-111
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 373 e-103
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 373 e-103
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 362 e-100
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 294 2e-79
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 285 2e-76
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 278 1e-74
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 277 3e-74
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 268 1e-71
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 268 1e-71
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 268 1e-71
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 261 2e-69
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 252 1e-66
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 252 1e-66
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 239 9e-63
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 224 3e-58
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 211 3e-54
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 202 2e-51
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 202 2e-51
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 199 1e-50
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 193 7e-49
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 187 3e-47
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 183 7e-46
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 183 7e-46
gi|13129006 nucleolar protein GU2 [Homo sapiens] 181 3e-45
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 180 5e-45
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 177 4e-44
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 176 7e-44
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 1910 bits (4948), Expect = 0.0
Identities = 938/938 (100%), Positives = 938/938 (100%)
Query: 1 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 60
MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY
Sbjct: 1 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 60
Query: 61 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 120
KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM
Sbjct: 61 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 120
Query: 121 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 180
AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN
Sbjct: 121 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 180
Query: 181 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 240
LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN
Sbjct: 181 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 240
Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG
Sbjct: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
Query: 301 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360
SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV
Sbjct: 301 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360
Query: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 420
YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ
Sbjct: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 420
Query: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480
VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS
Sbjct: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480
Query: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV
Sbjct: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
Query: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT
Sbjct: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
Query: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 660
LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY
Sbjct: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 660
Query: 661 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 720
RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK
Sbjct: 661 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 720
Query: 721 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 780
AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP
Sbjct: 721 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 780
Query: 781 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 840
SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH
Sbjct: 781 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 840
Query: 841 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 900
GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM
Sbjct: 841 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 900
Query: 901 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 938
EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS
Sbjct: 901 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 938
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 1910 bits (4948), Expect = 0.0
Identities = 938/938 (100%), Positives = 938/938 (100%)
Query: 1 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 60
MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY
Sbjct: 1 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 60
Query: 61 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 120
KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM
Sbjct: 61 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 120
Query: 121 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 180
AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN
Sbjct: 121 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 180
Query: 181 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 240
LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN
Sbjct: 181 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 240
Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG
Sbjct: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
Query: 301 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360
SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV
Sbjct: 301 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360
Query: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 420
YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ
Sbjct: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 420
Query: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480
VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS
Sbjct: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480
Query: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV
Sbjct: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
Query: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT
Sbjct: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
Query: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 660
LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY
Sbjct: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 660
Query: 661 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 720
RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK
Sbjct: 661 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 720
Query: 721 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 780
AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP
Sbjct: 721 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 780
Query: 781 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 840
SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH
Sbjct: 781 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 840
Query: 841 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 900
GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM
Sbjct: 841 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 900
Query: 901 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 938
EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS
Sbjct: 901 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 938
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 399 bits (1024), Expect = e-111
Identities = 235/603 (38%), Positives = 347/603 (57%), Gaps = 42/603 (6%)
Query: 77 EDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEE 136
ED+++D + PAE + + +D PL+A+M EV+++ + R +
Sbjct: 201 EDDDDDEDD------PAEAEKEGNEMEGEELD------PLDAYMEEVKEEVKKFNMRSVK 248
Query: 137 KD--KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPI---- 190
E+K+ + + ++A + + G + E ++D +EY S+ +
Sbjct: 249 GGGGNEKKSGPTVTKVVTVVTTKKAV---VDSDKKKGELMENDQDAMEYSSEEEEVDLQT 305
Query: 191 ------APTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN-LRV 243
+K+++P +DH +I+Y PF KNFY E E+ ++ +++ R ++ + V
Sbjct: 306 ALTGYQTKQRKLLEP---VDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITV 362
Query: 244 SGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGK 303
G P+P S+ G ++++ ++K Y +PTPIQ Q +P +SGRD+IGIAKTGSGK
Sbjct: 363 KGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGK 422
Query: 304 TAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGG 363
T AF+ PM HIMDQ+ LE G+GPIAVI+ PTREL QI ECK+F K LR V VYGG
Sbjct: 423 TIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGG 482
Query: 364 GSMWEQAKALQEGAEIVVCTPGRLIDHV---KKKATNLQRVSYLVFDEADRMFDMGFEYQ 420
+ EQ L+ GAEI+VCTPGR+ID + + TNL+RV+Y+V DEADRMFDMGFE Q
Sbjct: 483 TGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQ 542
Query: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480
V I +VRPDRQT++FSATF + +E LAR IL PI V G DV Q V ++
Sbjct: 543 VMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEE 602
Query: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
K+ L L + SGSV++FV K+ +A+ L +L + + LHG +DQ +R+ +
Sbjct: 603 -EKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSI 661
Query: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
I+DFK +LVAT VAARGLD+ + V+NY + + HR GRTGRAG KG AYT
Sbjct: 662 INDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYT 721
Query: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAW--FRKSRFKGGKGKKLNIGGGGL 658
+T + +AGD+++ LE + V +L + W F+ + GK K + G G
Sbjct: 722 FITEDQARYAGDIIKALELSGTAVPPDL-----EKLWSDFKDQQKAEGKIIKKSSGFSGK 776
Query: 659 GYR 661
G++
Sbjct: 777 GFK 779
Score = 31.6 bits (70), Expect = 3.6
Identities = 35/139 (25%), Positives = 47/139 (33%), Gaps = 16/139 (11%)
Query: 797 REGTGGSNGKRERYTE------NRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESS 850
R + G +G R R RG R S +R + R D R R
Sbjct: 11 RSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRR 70
Query: 851 SRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKMEPKVDS---- 906
SR + R E R S R +R + GR S N+ K E + K +
Sbjct: 71 SRSRERDRSRERRRSRSRDRR-RSRSRSRGRRSRSSSPG-NKSKKTENRSRSKEKTDGGE 128
Query: 907 ----SKMDKVDSKTDKTAD 921
K DK D + +K D
Sbjct: 129 SSKEKKKDKDDKEDEKEKD 147
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 373 bits (957), Expect = e-103
Identities = 224/620 (36%), Positives = 339/620 (54%), Gaps = 42/620 (6%)
Query: 174 QEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDY---PPFEKNFYNEHEEITNLTPQ 230
++ + D + + G P KK +P + + D P FEKNFY EH E+ LTP
Sbjct: 88 RDRDRDRGGFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPY 147
Query: 231 QLIDLRHKLNLRVSGA-APPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALS 289
++ +LR K + V G P+P +F H F + +M + +T+PTPIQCQG P+ALS
Sbjct: 148 EVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALS 207
Query: 290 GRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRF 349
GRDM+GIA+TGSGKT A++ P ++HI Q LE GDGPI +++ PTREL QQ+ +
Sbjct: 208 GRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDY 267
Query: 350 GKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEA 409
GK L+S +YGG Q + L+ G EI + TPGRLID ++ TNL+R +YLV DEA
Sbjct: 268 GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEA 327
Query: 410 DRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIG-EAN 468
DRM DMGFE Q+R I +RPDRQTL++SAT+ K++ +LA D L D ++ G++ AN
Sbjct: 328 DRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSAN 387
Query: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFVTKKANAEELANNLKQEGHNLG 526
++ QIV++ K + L + + E + ++FV K ++L ++++G
Sbjct: 388 HNILQIVDVCMES-EKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAM 446
Query: 527 LLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRI 586
+HGD Q ER+ V+++F+ P+L+ATDVA+RGLD+ +K VINYD + + HRI
Sbjct: 447 CIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRI 506
Query: 587 GRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646
GRT R+ KG AYT TP + A +L++ LE ANQ ++ +L+ L R GG
Sbjct: 507 GRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLV-------DHRGGGG 559
Query: 647 KGKKLNIGGGGLGYRERPGLGSENM---DRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAF 703
G K GG YR + N+ D + + + + + + DR +A +
Sbjct: 560 GGGK----GGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGY 615
Query: 704 ---------QSQYKSHFVAASLSNQKAGSSAAGASGWTS----AGSLNSVPTNSAQQGHN 750
S + + + G++A G S +T+ AG+ + T S G +
Sbjct: 616 ANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTTST--GRS 673
Query: 751 SPDSPVTSAAKGIPGFGNTG 770
S S+++ G G +G
Sbjct: 674 S-----QSSSQQFSGIGRSG 688
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 373 bits (957), Expect = e-103
Identities = 223/620 (35%), Positives = 338/620 (54%), Gaps = 44/620 (7%)
Query: 174 QEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDY---PPFEKNFYNEHEEITNLTPQ 230
++ + D + + G P KK +P + + D P FEKNFY EH E+ LTP
Sbjct: 88 RDRDRDRGGFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPY 147
Query: 231 QLIDLRHKLNLRVSGA-APPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALS 289
++ +LR K + V G P+P +F H F + +M + +T+PTPIQCQG P+ALS
Sbjct: 148 EVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALS 207
Query: 290 GRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRF 349
GRDM+GIA+TGSGKT A++ P ++HI Q LE GDGPI +++ PTREL QQ+ +
Sbjct: 208 GRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDY 267
Query: 350 GKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEA 409
GK L+S +YGG Q + L+ G EI + TPGRLID ++ TNL+R +YLV DEA
Sbjct: 268 GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEA 327
Query: 410 DRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIG-EAN 468
DRM DMGFE Q+R I +RPDRQTL++SAT+ K++ +LA D L D ++ G++ AN
Sbjct: 328 DRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSAN 387
Query: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFVTKKANAEELANNLKQEGHNLG 526
++ QIV++ K + L + + E + ++FV K ++L ++++G
Sbjct: 388 HNILQIVDVCMES-EKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAM 446
Query: 527 LLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRI 586
+HGD Q ER+ V+++F+ P+L+ATDVA+RGLD+ +K VINYD + + HRI
Sbjct: 447 CIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRI 506
Query: 587 GRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646
GRT R+ KG AYT TP + A +L++ LE ANQ ++ +L+ L GG
Sbjct: 507 GRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRG--------GG 558
Query: 647 KGKKLNIGGGGLGYRERPGLGSENM---DRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAF 703
G GGG YR + N+ D + + + + + + DR +A +
Sbjct: 559 GG-----GGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGY 613
Query: 704 ---------QSQYKSHFVAASLSNQKAGSSAAGASGWTS----AGSLNSVPTNSAQQGHN 750
S + + + G++A G S +T+ AG+ + T S G +
Sbjct: 614 ANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTTST--GRS 671
Query: 751 SPDSPVTSAAKGIPGFGNTG 770
S S+++ G G +G
Sbjct: 672 S-----QSSSQQFSGIGRSG 686
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 362 bits (929), Expect = e-100
Identities = 213/552 (38%), Positives = 311/552 (56%), Gaps = 37/552 (6%)
Query: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQI 268
+ P FEKNFY EH ++ T Q++ R + V G P+P +F F +M I
Sbjct: 50 ELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVI 109
Query: 269 RKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPI 328
+ +T+PT IQ QG PVALSG DM+G+A+TGSGKT +++ P ++HI Q LE GDGPI
Sbjct: 110 ARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPI 169
Query: 329 AVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLI 388
+++ PTREL QQ+ + +A L+S +YGG Q + L+ G EI + TPGRLI
Sbjct: 170 CLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLI 229
Query: 389 DHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKL 448
D ++ TNL+R +YLV DEADRM DMGFE Q+R I +RPDRQTL++SAT+ K++ +L
Sbjct: 230 DFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQL 289
Query: 449 ARDILIDPIRVVQGDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFV 505
A D L D I + G + AN ++ QIV++ H K L R + E S ++FV
Sbjct: 290 AEDFLKDYIHINIGALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFV 348
Query: 506 TKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIP 565
K +EL ++++G +HGD Q ER+ V+++FK P+L+ATDVA+RGLD+
Sbjct: 349 ETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVE 408
Query: 566 SIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVS 625
+K VINYD + + HRIGRT R+ + G AYT TP + DL+ L ANQ ++
Sbjct: 409 DVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAIN 468
Query: 626 KELLDLAMQNAWFRKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVM 679
+LL L +++ +SR +GG + + + G GG +R+R EN DRG ++++
Sbjct: 469 PKLLQL-VEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLL 522
Query: 680 SNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNS 739
K G + AA+ +N GS+ A TS + N
Sbjct: 523 KRDFGAKTQNGV-------------------YSAANYTNGSFGSNFVSAGIQTSFRTGN- 562
Query: 740 VPTNSAQQGHNS 751
PT + Q G++S
Sbjct: 563 -PTGTYQNGYDS 573
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 294 bits (753), Expect = 2e-79
Identities = 169/452 (37%), Positives = 262/452 (57%), Gaps = 20/452 (4%)
Query: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVS------GAAPPRPGSSFAH---FG 259
D PP +KNFY E + ++ + D K N ++ G P P + F
Sbjct: 190 DLPPIKKNFYKESTATSAMSKVEA-DSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQ 248
Query: 260 FDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK 319
++M I+K+ + +PTPIQ Q P+ L G D+IG+A+TG+GKT ++ P IH++ Q
Sbjct: 249 CYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQP 308
Query: 320 ELE-PGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAE 378
L+ + P +++ PTREL Q+ EC ++ LRSV VYGGG+ EQ + L++G +
Sbjct: 309 SLKGQRNRPGMLVLTPTRELALQVEGECCKYSYK-GLRSVCVYGGGNRDEQIEELKKGVD 367
Query: 379 IVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFS 438
I++ TPGRL D NL+ ++YLV DEAD+M DMGFE Q+ I VRPDRQT++ S
Sbjct: 368 IIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTS 427
Query: 439 ATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSS 498
AT+ + +LA+ L +P+ V G + + I+ + KW+ + L +S+
Sbjct: 428 ATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSST 487
Query: 499 GSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558
V++FV++KA A+ L+++L ++ LHGD +Q +R K + +FK + +L+ATD+A
Sbjct: 488 DKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLA 547
Query: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLE 618
+RGLD+ + V N+D R+I+ + HRIGRTGRAG GV+ T LT D A +L+ LE
Sbjct: 548 SRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILE 607
Query: 619 GANQHVSKELLDLAMQNAWFRKSRFKGGKGKK 650
ANQ + +EL+ +A RFK + K+
Sbjct: 608 RANQSIPEELVSMA--------ERFKAHQQKR 631
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 285 bits (728), Expect = 2e-76
Identities = 214/622 (34%), Positives = 308/622 (49%), Gaps = 64/622 (10%)
Query: 65 KRANFDEENAY-FEDEEEDSSNVD-LPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAE 122
KRA DE A E ED + D +PY+P RQ K + AE
Sbjct: 9 KRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQR--RQLLLQKLLQRRRKG------AAE 60
Query: 123 VEDQAARDMKRLEEKD---KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQE---E 176
E Q + R +E D + NV + DQ + + AE ++ E
Sbjct: 61 EEQQDSGSEPRGDEDDIPLGPQSNVSLL--------DQHQHLKEKAEARKESAKEKQLKE 112
Query: 177 EEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLR 236
EE LE ++G + K++ I Y K + + +++ ++ +R
Sbjct: 113 EEKILESVAEGRALMSVKEMA--------KGITYDDPIKTSWTPPRYVLSMSEERHERVR 164
Query: 237 HKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGI 296
K ++ V G P P SF F ++ ++K PTPIQ QG+P LSGRDMIGI
Sbjct: 165 KKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGI 224
Query: 297 AKTGSGKTAAFIWPMLIHIMDQKELEP---GDGPIAVIVCPTRELCQQIHAECKRFGKAY 353
A TGSGKT F P+++ ++Q++ P +GP +I+CP+REL +Q H + + +
Sbjct: 225 AFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLL 284
Query: 354 N------LRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFD 407
LR GG S+ EQ + ++ G ++V TPGRL+D ++KK +L YL D
Sbjct: 285 QEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALD 344
Query: 408 EADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEA 467
EADRM DMGFE +R+I S+ + RQTLLFSAT KKI+ A+ L+ P+ + G G A
Sbjct: 345 EADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAA 404
Query: 468 NEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGL 527
+ DV Q VE + +K +L L + + VL+F KKA+ + + L +G
Sbjct: 405 SLDVIQEVEYVKE-EAKMVYLLECLQK--TPPPVLIFAEKKADVDAIHEYLLLKGVEAVA 461
Query: 528 LHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIG 587
+HG DQ ER K I F++ VLVATDVA++GLD P+I+ VINYD+ +I+ + HRIG
Sbjct: 462 IHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIG 521
Query: 588 RTGRAGEKGVAYTLLTPK-DSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646
RTGR+G G+A T + D + DL L A Q V L L G
Sbjct: 522 RTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHC------------G 569
Query: 647 KGKKLNIGG-------GGLGYR 661
L+IGG GGLG+R
Sbjct: 570 DESMLDIGGERGCAFCGGLGHR 591
>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
sapiens]
Length = 631
Score = 278 bits (712), Expect = 1e-74
Identities = 163/453 (35%), Positives = 265/453 (58%), Gaps = 14/453 (3%)
Query: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRV------SGAAP--PRPGSSFAH-FG 259
D PP +KNFY E + + ++ Q+I+ R K N + SG P+P F F
Sbjct: 170 DLPPVKKNFYIESKATSCMSEMQVINWR-KENFNITCDDLKSGEKRLIPKPTCRFKDAFQ 228
Query: 260 FDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK 319
L+ I + +PTPIQ Q P+ L G D+I +A+TG+GKT +++ P IH+ Q
Sbjct: 229 QYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQP 288
Query: 320 -ELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAE 378
E +GP +++ PTREL + AEC ++ L+S+ +YGG + Q + + +G +
Sbjct: 289 ISREQRNGPGMLVLTPTRELALHVEAECSKYSYK-GLKSICIYGGRNRNGQIEDISKGVD 347
Query: 379 IVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFS 438
I++ TPGRL D + NL+ ++YLV DEAD+M DM FE Q+R I VRPDRQT++ S
Sbjct: 348 IIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTS 407
Query: 439 ATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTS- 497
AT+ + +LA L DP+ V G++ + + I+ + K LT+ VE S
Sbjct: 408 ATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEK-RALTQEFVENMSP 466
Query: 498 SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDV 557
+ V++FV++K A++L+++ +G + LHG+ +QS++ + + DFK +I +L+ TD+
Sbjct: 467 NDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526
Query: 558 AARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNL 617
+RGLD+ + V NYD R+ID + HR+G GR G+ G + TL+T +DS AG+L++ L
Sbjct: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586
Query: 618 EGANQHVSKELLDLAMQNAWFRKSRFKGGKGKK 650
+ ANQ V ++L+ +A Q ++ R + + +K
Sbjct: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRK 619
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 277 bits (709), Expect = 3e-74
Identities = 162/416 (38%), Positives = 234/416 (56%), Gaps = 32/416 (7%)
Query: 222 EEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQC 281
+++ +T + R ++ G P P S+ ++ I K Y +PTPIQ
Sbjct: 360 KKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQR 419
Query: 282 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKEL----EPGDGPIAVIVCPTRE 337
Q +P+ L RD+IG+A+TGSGKTAAF+ P+L+ I ++ E GP A+I+ PTRE
Sbjct: 420 QAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRE 479
Query: 338 LCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATN 397
L QQI E +FGK +R+VAV GG S +Q L+ G EIV+ TPGRLID ++ +
Sbjct: 480 LAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLV 539
Query: 398 LQRVSYLVFDEADRMFDMGFEYQVRSIASHV-----RPD--------------------- 431
L R +Y+V DEADRM DMGFE V+ I H+ +PD
Sbjct: 540 LSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKY 599
Query: 432 RQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRR 491
RQT++F+AT +E+LAR L P V G G+ +E V Q V ++ + L
Sbjct: 600 RQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLA-- 657
Query: 492 LVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPV 551
++E +++FV +K + LA +L++ G+N LHG Q +R +S+ K +
Sbjct: 658 ILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDI 717
Query: 552 LVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDS 607
LVATDVA RG+DI + V+NYD+A++I+ + HRIGRTGRAG+ GVA T LT +DS
Sbjct: 718 LVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDS 773
Score = 36.6 bits (83), Expect = 0.11
Identities = 23/110 (20%), Positives = 48/110 (43%), Gaps = 2/110 (1%)
Query: 794 NNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPR-HGDGGRHGDGYRHPESSSR 852
+ R+ + + KR R + R S + ++ ++ R H + R + R+ + R
Sbjct: 33 DRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERERDKERDRNKKDRDR 92
Query: 853 HTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKMEP 902
DGHR ++R S G + ++ +S+K+ + +PK +P
Sbjct: 93 DKDGHRRDKDRKRSSLS-PGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQP 141
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 268 bits (686), Expect = 1e-71
Identities = 161/437 (36%), Positives = 238/437 (54%), Gaps = 25/437 (5%)
Query: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313
SF+ E +M I + YT+PTP+Q +P+ RD++ A+TGSGKTAAF+ P+L
Sbjct: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240
Query: 314 HIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHAECKRFGKAYNLRS 357
I PG+ PI++++ PTREL QI+ E ++F +R
Sbjct: 241 QIYSDG---PGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRP 297
Query: 358 VAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGF 417
VYGG + +Q + L+ G ++V TPGRL+D +++ L YLV DEADRM DMGF
Sbjct: 298 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 357
Query: 418 EYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQ 473
E Q+R I + R T++FSATF K+I+ LARD L + I + G +G +E++TQ
Sbjct: 358 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 417
Query: 474 IVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMD 533
V + K ++L L L+FV K A+ L + L EG+ +HGD
Sbjct: 418 KVVWVEES-DKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRS 476
Query: 534 QSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAG 593
Q +R + + F+ P+LVAT VAARGLDI ++K VIN+D+ DI+ + HRIGRTGR G
Sbjct: 477 QRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 536
Query: 594 EKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNI 653
G+A + ++ N DL+ L A Q V L ++A ++ + SR + K + +
Sbjct: 537 NLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGR-SKSSRFSG 595
Query: 654 GGGGLGYRERPGLGSEN 670
G G YR+ G S +
Sbjct: 596 GFGARDYRQSSGASSSS 612
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 268 bits (686), Expect = 1e-71
Identities = 165/459 (35%), Positives = 248/459 (54%), Gaps = 27/459 (5%)
Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
+ +G+ P +F+ E +M I + YT+PTP+Q +P+ RD++ A+TG
Sbjct: 166 VEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTG 225
Query: 301 SGKTAAFIWPMLIHIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHA 344
SGKTAAF+ P+L I PG+ PI++++ PTREL QI+
Sbjct: 226 SGKTAAFLLPILSQIYTDG---PGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYE 282
Query: 345 ECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYL 404
E ++F +R VYGG + +Q + L+ G ++V TPGRL+D +++ L YL
Sbjct: 283 EARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYL 342
Query: 405 VFDEADRMFDMGFEYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVV 460
V DEADRM DMGFE Q+R I + R T++FSATF K+I+ LARD L + I +
Sbjct: 343 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLA 402
Query: 461 QGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ 520
G +G +E++TQ V + K ++L L S L+FV K A+ L + L
Sbjct: 403 VGRVGSTSENITQKV-VWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYH 461
Query: 521 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID 580
EG+ +HGD Q +R + + F+ P+LVAT VAARGLDI +++ VIN+D+ DI+
Sbjct: 462 EGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIE 521
Query: 581 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK 640
+ HRIGRTGR G G+A + K+ N DL+ L A Q V L ++A ++ +
Sbjct: 522 EYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGG 581
Query: 641 SRFKGGKGKKLNIGGGGLGYRERPGLGSENM--DRGNNN 677
SR + K + + G G YR+ G S RG+++
Sbjct: 582 SRGR-SKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSS 619
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 268 bits (686), Expect = 1e-71
Identities = 165/459 (35%), Positives = 248/459 (54%), Gaps = 27/459 (5%)
Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
+ +G+ P +F+ E +M I + YT+PTP+Q +P+ RD++ A+TG
Sbjct: 166 VEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTG 225
Query: 301 SGKTAAFIWPMLIHIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHA 344
SGKTAAF+ P+L I PG+ PI++++ PTREL QI+
Sbjct: 226 SGKTAAFLLPILSQIYTDG---PGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYE 282
Query: 345 ECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYL 404
E ++F +R VYGG + +Q + L+ G ++V TPGRL+D +++ L YL
Sbjct: 283 EARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYL 342
Query: 405 VFDEADRMFDMGFEYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVV 460
V DEADRM DMGFE Q+R I + R T++FSATF K+I+ LARD L + I +
Sbjct: 343 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLA 402
Query: 461 QGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ 520
G +G +E++TQ V + K ++L L S L+FV K A+ L + L
Sbjct: 403 VGRVGSTSENITQKV-VWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYH 461
Query: 521 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID 580
EG+ +HGD Q +R + + F+ P+LVAT VAARGLDI +++ VIN+D+ DI+
Sbjct: 462 EGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIE 521
Query: 581 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK 640
+ HRIGRTGR G G+A + K+ N DL+ L A Q V L ++A ++ +
Sbjct: 522 EYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGG 581
Query: 641 SRFKGGKGKKLNIGGGGLGYRERPGLGSENM--DRGNNN 677
SR + K + + G G YR+ G S RG+++
Sbjct: 582 SRGR-SKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSS 619
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 261 bits (667), Expect = 2e-69
Identities = 206/660 (31%), Positives = 313/660 (47%), Gaps = 99/660 (15%)
Query: 7 GPGTKRGFGFGGFAISA--GKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFYKIGS 64
GP + F GFA G ++ + ++ + TS+ GFG +G
Sbjct: 47 GPSRRDHFMKSGFASGRNFGNRDAGECNKRDN-----TSTMGGFG------------VGK 89
Query: 65 KRANFDEENAYFEDEEE-----DSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDD----- 114
N N+ FED + +SSN E++PTR + SK D+D D D
Sbjct: 90 SFGNRGFSNSRFEDGDSSGFWRESSN------DCEDNPTRNRGFSKRGDNDLDPDECMQR 143
Query: 115 ---------PLEAFMAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMA 165
P+ + + +R ER KG+ +++ + ++
Sbjct: 144 TGGLFGSRRPVLSGTGNGDTSQSRS-----GSGSERGGYKGLNEEVITGSGKNSW----- 193
Query: 166 ENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEIT 225
+ E E D+ G P I P PP D E + + ++
Sbjct: 194 --------KSEAEGGESSDTQG----PKVTYIPPPPPED---------EDSIFAHYQTGI 232
Query: 226 NLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVP 285
N D + + VSG P +F + L + I K+ YT+ TP+Q +P
Sbjct: 233 NF------DKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIP 286
Query: 286 VALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQ-------KELEPGDGPIAVIVCPTREL 338
+ L+GRD++ A+TGSGKTAAF+ P+L H+M KEL+ P +IV PTREL
Sbjct: 287 IILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE---PECIIVAPTREL 343
Query: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNL 398
QI+ E ++F +R+V +YGG + + + +G I+ TPGRL+D + K+ L
Sbjct: 344 VNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGL 403
Query: 399 QRVSYLVFDEADRMFDMGFEYQVRSIAS----HVRPDRQTLLFSATFRKKIEKLARDIL- 453
+++ YLV DEADRM DMGF +++ + S + RQTL+FSATF ++I++LA + L
Sbjct: 404 KQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLK 463
Query: 454 IDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEE 513
+ + V G +G A DV Q V L G ++ ++FV K A+
Sbjct: 464 SNYLFVAVGQVGGACRDVQQTV--LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADF 521
Query: 514 LANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINY 573
+A L QE + +HGD +Q ER + + DF+ PVLVAT VAARGLDI +++ VIN+
Sbjct: 522 IATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINF 581
Query: 574 DVARDIDTHTHRIGRTGRAGEKGVAYTLL-TPKDSNFAGDLVRNLEGANQHVSKELLDLA 632
D+ ID + HRIGRTGR G G A + D++ A LV+ L A Q V L ++A
Sbjct: 582 DLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 641
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 252 bits (644), Expect = 1e-66
Identities = 156/405 (38%), Positives = 229/405 (56%), Gaps = 18/405 (4%)
Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
+ VSG P +F + L + I K+ YT+ TP+Q +P+ L+GRD++ A+TG
Sbjct: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335
Query: 301 SGKTAAFIWPMLIHIMDQ-------KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAY 353
SGKTAAF+ P+L H+M KEL+ P +IV PTREL QI+ E ++F
Sbjct: 336 SGKTAAFLLPILAHMMHDGITASRFKELQE---PECIIVAPTRELVNQIYLEARKFSFGT 392
Query: 354 NLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMF 413
+R+V +YGG + + + +G I+ TPGRL+D + K+ L+++ YLV DEADRM
Sbjct: 393 CVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452
Query: 414 DMGFEYQVRSIAS----HVRPDRQTLLFSATFRKKIEKLARDIL-IDPIRVVQGDIGEAN 468
DMGF +++ + S + RQTL+FSATF ++I++LA + L + + V G +G A
Sbjct: 453 DMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGAC 512
Query: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLL 528
DV Q V L G ++ ++FV K A+ +A L QE + +
Sbjct: 513 RDVQQTV--LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSI 570
Query: 529 HGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGR 588
HGD +Q ER + + DF+ PVLVAT VAARGLDI +++ VIN+D+ ID + HRIGR
Sbjct: 571 HGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGR 630
Query: 589 TGRAGEKGVAYTLL-TPKDSNFAGDLVRNLEGANQHVSKELLDLA 632
TGR G G A + D++ A LV+ L A Q V L ++A
Sbjct: 631 TGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 675
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 252 bits (644), Expect = 1e-66
Identities = 156/405 (38%), Positives = 229/405 (56%), Gaps = 18/405 (4%)
Query: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300
+ VSG P +F + L + I K+ YT+ TP+Q +P+ L+GRD++ A+TG
Sbjct: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335
Query: 301 SGKTAAFIWPMLIHIMDQ-------KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAY 353
SGKTAAF+ P+L H+M KEL+ P +IV PTREL QI+ E ++F
Sbjct: 336 SGKTAAFLLPILAHMMHDGITASRFKELQE---PECIIVAPTRELVNQIYLEARKFSFGT 392
Query: 354 NLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMF 413
+R+V +YGG + + + +G I+ TPGRL+D + K+ L+++ YLV DEADRM
Sbjct: 393 CVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452
Query: 414 DMGFEYQVRSIAS----HVRPDRQTLLFSATFRKKIEKLARDIL-IDPIRVVQGDIGEAN 468
DMGF +++ + S + RQTL+FSATF ++I++LA + L + + V G +G A
Sbjct: 453 DMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGAC 512
Query: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLL 528
DV Q V L G ++ ++FV K A+ +A L QE + +
Sbjct: 513 RDVQQTV--LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSI 570
Query: 529 HGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGR 588
HGD +Q ER + + DF+ PVLVAT VAARGLDI +++ VIN+D+ ID + HRIGR
Sbjct: 571 HGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGR 630
Query: 589 TGRAGEKGVAYTLL-TPKDSNFAGDLVRNLEGANQHVSKELLDLA 632
TGR G G A + D++ A LV+ L A Q V L ++A
Sbjct: 631 TGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 675
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 239 bits (610), Expect = 9e-63
Identities = 152/460 (33%), Positives = 240/460 (52%), Gaps = 17/460 (3%)
Query: 206 SEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLM 265
SE + P Y EH I NL Q+ +L+ +L + V G RP F H E L
Sbjct: 156 SEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN 215
Query: 266 HQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGD 325
H ++KS Y PTPIQ Q +PV L GRD++ A TGSGKTAAF+ P+++ + + +
Sbjct: 216 HNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESKT---- 271
Query: 326 GPIAVIVCPTRELCQQIHAECKRFGKAY-NLRSVAVYGGGSMWEQAKALQEGAEIVVCTP 384
P A+I+ PTREL QI + K +++V + GG + Q LQ+ ++++ TP
Sbjct: 272 -PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATP 330
Query: 385 GRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKK 444
GRL+D +K+ + L V +V DEAD M MGF+ QV I ++ D QT+L SAT
Sbjct: 331 GRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTS 390
Query: 445 IEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGS---- 500
IE+LA +L +P+R++ G+ +V QI+ + P+K ++L E +
Sbjct: 391 IEQLASQLLHNPVRIITGEKNLPCANVRQII-LWVEDPAK----KKKLFEILNDKKLFKP 445
Query: 501 -VLLFVTKKANAEELANNL-KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558
VL+FV K A+ L+ + K G +H + Q ER ++ + D V+V+T V
Sbjct: 446 PVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVL 505
Query: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLE 618
RGLD+ S++ V+N+D+ +D + H+IGR GR G+ G A T + D+ + ++
Sbjct: 506 GRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVK 565
Query: 619 GANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGL 658
+ +LL+ + RK + K + + + G L
Sbjct: 566 PTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLVTGANL 605
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 224 bits (571), Expect = 3e-58
Identities = 136/356 (38%), Positives = 200/356 (56%), Gaps = 12/356 (3%)
Query: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313
+F G + L + +T+PT IQ + +P+AL GRD+IG+A+TGSGKT AF P+L
Sbjct: 25 TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84
Query: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373
+ LE A+++ PTREL QI + + G + ++S + GG Q+ AL
Sbjct: 85 AL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL 139
Query: 374 QEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR 432
+ I++ TPGRLIDH++ K NL+ + YLV DEADR+ +M FE +V I + DR
Sbjct: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199
Query: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWN--WLTR 490
+T LFSAT KK++KL R L +P++ + E + Q + PSK+ +L
Sbjct: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI---PSKFKDTYLVY 256
Query: 491 RLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIP 550
L E + S ++F + N + A L+ G LHG M QS+R ++ FK K
Sbjct: 257 ILNELAGN-SFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARS 315
Query: 551 VLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
+L+ATDVA+RGLDIP + V+N+D+ + HR+GRT RAG G A T +T D
Sbjct: 316 ILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYD 371
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 211 bits (536), Expect = 3e-54
Identities = 150/501 (29%), Positives = 248/501 (49%), Gaps = 45/501 (8%)
Query: 123 VEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLE 182
++++ + K+ + +DKE K+ K +E+E + + G +E+ED E
Sbjct: 117 LDEKIEKVRKKRKTEDKEAKSGK-----LEKEKEAKE-----------GSEPKEQEDLQE 160
Query: 183 YDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLR 242
D +G+ + SE DY ++N + + + ++ +
Sbjct: 161 NDEEGSED-------------EASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGF 207
Query: 243 VSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSG 302
A+ SF L+ I + QPTPIQ +PV L G+D+ A TG+G
Sbjct: 208 FEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTG 267
Query: 303 KTAAFIWPMLIHIMDQKELEPGDGPIA--VIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360
KTAAF P+L ++ +P P+ +++ PTREL Q+H+ ++ + N+ +
Sbjct: 268 KTAAFALPVLERLI----YKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLA 323
Query: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEY 419
GG + Q AL+ +I++ TPGRLIDH+ + +L + L+ DEADRM D FE
Sbjct: 324 VGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEE 383
Query: 420 QVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIV--EI 477
Q++ I RQT+LFSAT +++ LA L +P+R+ +N DV + E
Sbjct: 384 QMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVN----SNTDVAPFLRQEF 439
Query: 478 LHSGPSKWN---WLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQ 534
+ P++ + L+ T + V+LF K A + L G +G LHG++ Q
Sbjct: 440 IRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQ 499
Query: 535 SERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGE 594
++R + + FK + I +LVATDVAARGLDI +KTVIN+ + I + HR+GRT RAG
Sbjct: 500 TQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGR 559
Query: 595 KGVAYTLLTPKDSNFAGDLVR 615
G + +L+ + ++V+
Sbjct: 560 AGRSVSLVGEDERKMLKEIVK 580
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 202 bits (513), Expect = 2e-51
Identities = 124/364 (34%), Positives = 183/364 (50%), Gaps = 3/364 (0%)
Query: 250 RPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIW 309
+ F G + I K Y PTPIQ + +PV L G+D++ +A+TGSGKTA F+
Sbjct: 93 KKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLL 152
Query: 310 PMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ 369
PM + K G A+I+ PTREL Q K GK L++ + GG M +Q
Sbjct: 153 PMFERL---KTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQ 209
Query: 370 AKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVR 429
AL E +I++ TPGRL+ + + LQ V Y+VFDEADR+F+MGF Q++ I + +
Sbjct: 210 FAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLP 269
Query: 430 PDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT 489
QT+LFSAT K + + AR L +P+ + + NE + ++ L
Sbjct: 270 GGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLH 329
Query: 490 RRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDI 549
++FV K +AE L L + + ++ +D + R ++ F
Sbjct: 330 LLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKC 389
Query: 550 PVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNF 609
L+ TD+AARGLDIP + VINY HR+GR RAG G AY+L+ P + +
Sbjct: 390 STLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPY 449
Query: 610 AGDL 613
DL
Sbjct: 450 LLDL 453
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 202 bits (513), Expect = 2e-51
Identities = 124/364 (34%), Positives = 183/364 (50%), Gaps = 3/364 (0%)
Query: 250 RPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIW 309
+ F G + I K Y PTPIQ + +PV L G+D++ +A+TGSGKTA F+
Sbjct: 93 KKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLL 152
Query: 310 PMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ 369
PM + K G A+I+ PTREL Q K GK L++ + GG M +Q
Sbjct: 153 PMFERL---KTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQ 209
Query: 370 AKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVR 429
AL E +I++ TPGRL+ + + LQ V Y+VFDEADR+F+MGF Q++ I + +
Sbjct: 210 FAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLP 269
Query: 430 PDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT 489
QT+LFSAT K + + AR L +P+ + + NE + ++ L
Sbjct: 270 GGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLH 329
Query: 490 RRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDI 549
++FV K +AE L L + + ++ +D + R ++ F
Sbjct: 330 LLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKC 389
Query: 550 PVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNF 609
L+ TD+AARGLDIP + VINY HR+GR RAG G AY+L+ P + +
Sbjct: 390 STLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPY 449
Query: 610 AGDL 613
DL
Sbjct: 450 LLDL 453
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 199 bits (505), Expect = 1e-50
Identities = 135/396 (34%), Positives = 203/396 (51%), Gaps = 30/396 (7%)
Query: 253 SSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPML 312
+ FA G L+ Q R+ QPTP+Q +P L GRD +G AKTGSGKTAAF+ P+L
Sbjct: 2 AGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPIL 61
Query: 313 IHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKA 372
QK E G +++ PTREL QI + + GK L+ + GG M QA
Sbjct: 62 -----QKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALE 116
Query: 373 LQEGAEIVVCTPGRLIDHVKKKAT-NLQRVSYLVFDEADRMFDMG---FEYQVRSIASHV 428
L +V+ TPGRL DH++ T +++++ +LV DEADR+ + G F + +I + V
Sbjct: 117 LSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAV 176
Query: 429 RPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSG---PSKW 485
RQTLLFSAT + +L + Q EA V+ + ++ P K
Sbjct: 177 PARRQTLLFSATLTDTLREL------QGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKV 230
Query: 486 N-----WLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
L +R + S+++F + L L++ LH M Q ER
Sbjct: 231 KDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAA 290
Query: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
++ FK +L+ATDVA+RGLDIP+++ VIN++ + HR+GRT RAG +G A T
Sbjct: 291 LAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAIT 350
Query: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNA 636
L+T D + LV +E + + K+L + +++ A
Sbjct: 351 LVTQYDIH----LVHAIE---EQIKKKLEEFSVEEA 379
>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
[Homo sapiens]
Length = 406
Score = 193 bits (490), Expect = 7e-49
Identities = 122/354 (34%), Positives = 180/354 (50%), Gaps = 57/354 (16%)
Query: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313
+F G + L + +T+PT IQ + +P+AL GRD+IG+A+TGSGKT AF P+L
Sbjct: 25 TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84
Query: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373
+ LE A+++ PTREL QI + + G + ++S + GG Q+ AL
Sbjct: 85 AL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL 139
Query: 374 QEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR 432
+ I++ TPGRLIDH++ K NL+ + YLV DEADR+ +M FE +V I + DR
Sbjct: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199
Query: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRL 492
+T LFSAT KK++KL R L +P++ + E + Q + PSK+
Sbjct: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI---PSKF------- 249
Query: 493 VEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVL 552
+S+R ++ FK K +L
Sbjct: 250 -----------------------------------------KSKRLGSLNKFKAKARSIL 268
Query: 553 VATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
+ATDVA+RGLDIP + V+N+D+ + HR+GRT RAG G A T +T D
Sbjct: 269 LATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYD 322
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 187 bits (476), Expect = 3e-47
Identities = 116/383 (30%), Positives = 195/383 (50%), Gaps = 13/383 (3%)
Query: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313
+F G E L+ I + +P+ IQ + + + GRD+I +++G+GKTA F +L
Sbjct: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVL- 97
Query: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373
+D + E A+I+ PTREL QI G N++ A GG ++ E + L
Sbjct: 98 QCLDIQVRETQ----ALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKL 153
Query: 374 QEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQ 433
G +V TPGR+ D +++++ + + LV DEAD M + GF+ Q+ + ++ P Q
Sbjct: 154 DYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQ 213
Query: 434 TLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLV 493
+L SAT +I ++ + DPIR++ E + Q + K++ L
Sbjct: 214 VVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYD 273
Query: 494 EFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLV 553
T + +V+ F K + L +++ + +HGDM Q ER ++ +F+ VL+
Sbjct: 274 TLTITQAVI-FCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLI 332
Query: 554 ATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDL 613
+TDV ARGLD+P + +INYD+ + + + HRIGR+GR G KGVA + D
Sbjct: 333 STDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDD------- 385
Query: 614 VRNLEGANQHVSKELLDLAMQNA 636
+R L Q+ S ++ ++ M A
Sbjct: 386 IRILRDIEQYYSTQIDEMPMNVA 408
>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
sapiens]
Length = 491
Score = 183 bits (464), Expect = 7e-46
Identities = 134/396 (33%), Positives = 202/396 (51%), Gaps = 18/396 (4%)
Query: 223 EITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAH----FGFDEQLMHQIRKSEYTQPTP 278
++ NL +++ LR+K + V G P P ++F + + +L+ I + + PTP
Sbjct: 23 KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 82
Query: 279 IQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTREL 338
IQ Q +PV L GR+++ A TGSGKT AF P+L+ Q + G A+I+ PTREL
Sbjct: 83 IQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM----QLKQPANKGFRALIISPTREL 138
Query: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ-AKALQEGAEIVVCTPGRLIDHVKKK--A 395
QIH E + + R ++ ++ + +I+V TP RLI +K+
Sbjct: 139 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPG 198
Query: 396 TNLQRVSYLVFDEADRMFD---MGFEYQVRSIASHVRPDR-QTLLFSATFRKKIEKLARD 451
+L V +LV DE+D++F+ GF Q+ SI + + +FSATF +E+ +
Sbjct: 199 IDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKL 258
Query: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT-RRLVEFTSSGSVLLFVTKKAN 510
L + I V G A E V Q E+L G L R LV+ + VL+FV
Sbjct: 259 NLDNVISVSIGARNSAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIER 316
Query: 511 AEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTV 570
A+EL + L EG N+ ++H + Q +R+ + F+ I VL+ T + ARG+D + V
Sbjct: 317 AKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLV 376
Query: 571 INYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
INYD + HRIGRTGRAG KG A T T D
Sbjct: 377 INYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDD 412
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
Length = 599
Score = 183 bits (464), Expect = 7e-46
Identities = 134/396 (33%), Positives = 202/396 (51%), Gaps = 18/396 (4%)
Query: 223 EITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAH----FGFDEQLMHQIRKSEYTQPTP 278
++ NL +++ LR+K + V G P P ++F + + +L+ I + + PTP
Sbjct: 131 KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 190
Query: 279 IQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTREL 338
IQ Q +PV L GR+++ A TGSGKT AF P+L+ Q + G A+I+ PTREL
Sbjct: 191 IQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM----QLKQPANKGFRALIISPTREL 246
Query: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ-AKALQEGAEIVVCTPGRLIDHVKKK--A 395
QIH E + + R ++ ++ + +I+V TP RLI +K+
Sbjct: 247 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPG 306
Query: 396 TNLQRVSYLVFDEADRMFD---MGFEYQVRSIASHVRPDR-QTLLFSATFRKKIEKLARD 451
+L V +LV DE+D++F+ GF Q+ SI + + +FSATF +E+ +
Sbjct: 307 IDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKL 366
Query: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT-RRLVEFTSSGSVLLFVTKKAN 510
L + I V G A E V Q E+L G L R LV+ + VL+FV
Sbjct: 367 NLDNVISVSIGARNSAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIER 424
Query: 511 AEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTV 570
A+EL + L EG N+ ++H + Q +R+ + F+ I VL+ T + ARG+D + V
Sbjct: 425 AKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLV 484
Query: 571 INYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
INYD + HRIGRTGRAG KG A T T D
Sbjct: 485 INYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDD 520
>gi|13129006 nucleolar protein GU2 [Homo sapiens]
Length = 737
Score = 181 bits (459), Expect = 3e-45
Identities = 147/505 (29%), Positives = 237/505 (46%), Gaps = 57/505 (11%)
Query: 134 LEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPT 193
LEE + ++K + ++ D +++ Y ++ + E E+ + D D P A
Sbjct: 17 LEESESQKK-------ERQKSDRRKSRHHYDSDEKS-----ETRENGVTDDLDA-PKAKK 63
Query: 194 KKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGS 253
K+ + L +E + F H+ P ID K + RVS S
Sbjct: 64 SKMKEKLN--GDTEEGFNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKS 121
Query: 254 S----------------FAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIA 297
S F++F E+ + ++ T PIQ + G+D+I A
Sbjct: 122 SDNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQA 181
Query: 298 KTGSGKTAAFIWPMLIHIM-DQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLR 356
+TG+GKT +F P++ + +Q+ ++ P +++ PTREL Q+ + K + L
Sbjct: 182 RTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLS 239
Query: 357 SVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMG 416
YGG S Q ++ G +I+V TPGR+ DH++ +L ++ ++V DE D+M D+G
Sbjct: 240 VACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLG 299
Query: 417 FEYQVRSIA-----SHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGD-IGEANED 470
F QV I + + QTLLFSAT + + K+A+ + R Q D +G+ +
Sbjct: 300 FAEQVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKS--RYEQVDLVGKMTQK 357
Query: 471 VTQIVEILHSGPSKWNWLTRRLV-------EFTSSGSVLLFVTKKANAEELANN--LKQE 521
VE L + +W R V S G ++F K N E+A N +KQ
Sbjct: 358 AATTVEHL---AIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQ- 413
Query: 522 GHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDT 581
N LHGD+ QS+R + F++ VLVAT+VAARGLDIP + VI +D+++
Sbjct: 414 --NAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVES 471
Query: 582 HTHRIGRTGRAGEKGVAYTLLTPKD 606
+ HR GRTGRAG G+ P++
Sbjct: 472 YIHRSGRTGRAGRTGICICFYQPRE 496
Score = 34.7 bits (78), Expect = 0.43
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 21/119 (17%)
Query: 753 DSPVTSAAKGIPGFGNTGNISGAPVTYPSAGAQGVNNTASGNNSREGTGGSNGKRERYTE 812
D P T + + + ++ I P P NT+S NSR+ +G S+G+ R
Sbjct: 635 DVPTTESERLQAEWHDSDWILSVPAKLPEIEEYYDGNTSS--NSRQRSGWSSGRSGR--- 689
Query: 813 NRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESSSRHTDGHRHGENRHGGSAGRH 871
G +G R GGR G R S DG R NR+ +G H
Sbjct: 690 --------SGRSGGR--------SGGRSGRQSRQGSRSGSRQDGRRRSGNRNRSRSGGH 732
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 180 bits (457), Expect = 5e-45
Identities = 124/376 (32%), Positives = 199/376 (52%), Gaps = 29/376 (7%)
Query: 255 FAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIH 314
F+ F ++ + +++++Y T IQ Q + +AL G+D++G AKTGSGKT AF+ P+L
Sbjct: 71 FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVL-E 129
Query: 315 IMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQ 374
+ + + DG +I+ PTREL Q ++ GK ++ + + GG + +A+ +
Sbjct: 130 ALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERI- 188
Query: 375 EGAEIVVCTPGRLIDH----VKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRP 430
I+VCTPGRL+ H V AT+LQ LV DEADR+ DMGF + ++ ++
Sbjct: 189 NNINILVCTPGRLLQHMDETVSFHATDLQ---MLVLDEADRILDMGFADTMNAVIENLPK 245
Query: 431 DRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVT-----------QIVEILH 479
RQTLLFSAT K ++ LAR L +P V + + + T Q + +L+
Sbjct: 246 KRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLY 305
Query: 480 SGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNK 539
S + L ++ + F SS + ++ + + G ++ LHG Q R +
Sbjct: 306 S--FLRSHLKKKSIVFFSSCKEVQYLYR-------VFCRLRPGVSILALHGRQQQMRRME 356
Query: 540 VISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAY 599
V ++F +K VL ATD+AARGLD P++ V+ +D D +T+ HR GRT R E G A
Sbjct: 357 VYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEAL 416
Query: 600 TLLTPKDSNFAGDLVR 615
+L P + L++
Sbjct: 417 LILLPSEKAMVQQLLQ 432
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 177 bits (449), Expect = 4e-44
Identities = 111/364 (30%), Positives = 182/364 (50%), Gaps = 25/364 (6%)
Query: 252 GSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPM 311
G+ F + +L+ I + + +P+PIQ + +P+ALSGRD++ AK G+GK+ A++ P+
Sbjct: 95 GNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPL 154
Query: 312 LIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYN-LRSVAVYGGGSMWEQA 370
L + +K D A+++ PTREL Q+ C + K + +A GG ++ +
Sbjct: 155 LERLDLKK-----DNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDI 209
Query: 371 KALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRP 430
L + +V+ TPGR++D +KK + V +V DEAD++ F + I +
Sbjct: 210 MRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPK 269
Query: 431 DRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTR 490
+RQ LL+SATF ++K L P + E++T L + ++T
Sbjct: 270 NRQILLYSATFPLSVQKFMNSHLQKPYEI------NLMEELT-----LKGVTQYYAYVTE 318
Query: 491 R--------LVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVIS 542
R L ++F E LA + Q G++ +H M Q RN+V
Sbjct: 319 RQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFH 378
Query: 543 DFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLL 602
DF+ LV TD+ RG+DI ++ VIN+D + +T+ HRIGR+GR G G+A L+
Sbjct: 379 DFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLI 438
Query: 603 TPKD 606
T D
Sbjct: 439 TYDD 442
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 176 bits (447), Expect = 7e-44
Identities = 151/543 (27%), Positives = 246/543 (45%), Gaps = 72/543 (13%)
Query: 79 EEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEEKD 138
++ + S VD+ NSP ++ K S +D P + + ++ +E+K
Sbjct: 60 KKAEPSEVDM------NSPKSKKAKKKEEPSQNDISPKTKSLRKKKEP-------IEKKV 106
Query: 139 KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIID 198
K K +++ E++ +A P +++E+E N G + K+ +
Sbjct: 107 VSSKTKKVTKNEEPSEEEIDA--------PKPKKMKKEKEMN------GETREKSPKLKN 152
Query: 199 PLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHF 258
P H E D P E + EI P + + +F++F
Sbjct: 153 GFP---HPEPDCNPSEAASEESNSEIEQEIPVE------------------QKEGAFSNF 191
Query: 259 GFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQ 318
E+ + ++ T PIQ + SG+D+I A+TG+GKT +F P++ + +
Sbjct: 192 PISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGE 251
Query: 319 -KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGA 377
++ + G P +++ PTREL Q+ + K L YGG Q + ++ G
Sbjct: 252 LQDRKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACFYGGTPYGGQFERMRNGI 309
Query: 378 EIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHV-----RPDR 432
+I+V TPGR+ DH++ +L ++ ++V DE D+M DMGF QV I S +
Sbjct: 310 DILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNP 369
Query: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRL 492
QTLLFSAT + +A+ + V IG+ + VE L K +W R
Sbjct: 370 QTLLFSATCPHWVFNVAKKYMKSTYEQVDL-IGKKTQKTAITVEHL---AIKCHWTQRAA 425
Query: 493 V-------EFTSSGSVLLFVTKKANAEELANN--LKQEGHNLGLLHGDMDQSERNKVISD 543
V G ++F K A+EL+ N +KQ+ +L HGD+ Q +R +
Sbjct: 426 VIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSL---HGDIPQKQREITLKG 482
Query: 544 FKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLT 603
F+ VLVAT+VAARGLDIP + VI +D++++ HR GRTGRAG GV
Sbjct: 483 FRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQ 542
Query: 604 PKD 606
K+
Sbjct: 543 HKE 545
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,308,089
Number of Sequences: 37866
Number of extensions: 2088244
Number of successful extensions: 10506
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 131
Number of HSP's successfully gapped in prelim test: 401
Number of HSP's that attempted gapping in prelim test: 7757
Number of HSP's gapped (non-prelim): 1796
length of query: 938
length of database: 18,247,518
effective HSP length: 112
effective length of query: 826
effective length of database: 14,006,526
effective search space: 11569390476
effective search space used: 11569390476
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.