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Search of human proteins with 45433501
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45433501 elastin microfibril interfacer 3 [Homo sapiens]
(766 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45433501 elastin microfibril interfacer 3 [Homo sapiens] 1524 0.0
gi|60498978 elastin microfibril interfacer 2 [Homo sapiens] 223 4e-58
gi|5901944 elastin microfibril interfacer 1 [Homo sapiens] 166 8e-41
gi|118498339 EMI domain containing 2 [Homo sapiens] 89 1e-17
gi|50511941 EMI domain containing 1 [Homo sapiens] 88 3e-17
gi|221316695 multimerin 2 precursor [Homo sapiens] 64 7e-10
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 58 4e-08
gi|45269141 multimerin 1 [Homo sapiens] 55 3e-07
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 54 7e-07
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 54 7e-07
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 54 7e-07
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 52 2e-06
gi|110611218 ribosome binding protein 1 [Homo sapiens] 52 2e-06
gi|110611220 ribosome binding protein 1 [Homo sapiens] 52 2e-06
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 52 3e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 50 8e-06
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 50 8e-06
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 49 2e-05
gi|126723390 ankyrin repeat domain 24 [Homo sapiens] 48 3e-05
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 48 4e-05
gi|157042792 coiled-coil domain containing 64B [Homo sapiens] 46 1e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 45 3e-04
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 45 3e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 45 3e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 45 3e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 45 3e-04
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 45 3e-04
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 44 4e-04
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 44 6e-04
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 44 6e-04
>gi|45433501 elastin microfibril interfacer 3 [Homo sapiens]
Length = 766
Score = 1524 bits (3947), Expect = 0.0
Identities = 766/766 (100%), Positives = 766/766 (100%)
Query: 1 MGRRRLLVWLCAVAALLSGAQARGTPLLARPAPPGASRYSLYTTGWRPRLRPGPHKALCA 60
MGRRRLLVWLCAVAALLSGAQARGTPLLARPAPPGASRYSLYTTGWRPRLRPGPHKALCA
Sbjct: 1 MGRRRLLVWLCAVAALLSGAQARGTPLLARPAPPGASRYSLYTTGWRPRLRPGPHKALCA 60
Query: 61 YVVHRNVTCILQEGAESYVKAEYRQCRWGPKCPGTVTYRTVLRPKYKVGYKTVTDLAWRC 120
YVVHRNVTCILQEGAESYVKAEYRQCRWGPKCPGTVTYRTVLRPKYKVGYKTVTDLAWRC
Sbjct: 61 YVVHRNVTCILQEGAESYVKAEYRQCRWGPKCPGTVTYRTVLRPKYKVGYKTVTDLAWRC 120
Query: 121 CPGFTGKRCPEHLTDHGAASPQLEPEPQIPSGQLDPGPRPPSYSRAAPSPHGRKGPGLFG 180
CPGFTGKRCPEHLTDHGAASPQLEPEPQIPSGQLDPGPRPPSYSRAAPSPHGRKGPGLFG
Sbjct: 121 CPGFTGKRCPEHLTDHGAASPQLEPEPQIPSGQLDPGPRPPSYSRAAPSPHGRKGPGLFG 180
Query: 181 ERLERLEGDVQRLAQTYGTLSGLVASHEDPNRMTGGPRAPAVPVGFGVIPEGLVGPGDRA 240
ERLERLEGDVQRLAQTYGTLSGLVASHEDPNRMTGGPRAPAVPVGFGVIPEGLVGPGDRA
Sbjct: 181 ERLERLEGDVQRLAQTYGTLSGLVASHEDPNRMTGGPRAPAVPVGFGVIPEGLVGPGDRA 240
Query: 241 RGPLTPPLDEILSKVTEVSNTLQTKVQLLDKVHGLALGHEAHLQRLREAPPSPLTSLALL 300
RGPLTPPLDEILSKVTEVSNTLQTKVQLLDKVHGLALGHEAHLQRLREAPPSPLTSLALL
Sbjct: 241 RGPLTPPLDEILSKVTEVSNTLQTKVQLLDKVHGLALGHEAHLQRLREAPPSPLTSLALL 300
Query: 301 EEYVDRRLHRLWGSLLDGFEQKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGREL 360
EEYVDRRLHRLWGSLLDGFEQKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGREL
Sbjct: 301 EEYVDRRLHRLWGSLLDGFEQKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGREL 360
Query: 361 ALRQELSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDEL 420
ALRQELSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDEL
Sbjct: 361 ALRQELSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDEL 420
Query: 421 TRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEER 480
TRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEER
Sbjct: 421 TRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEER 480
Query: 481 LATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAW 540
LATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAW
Sbjct: 481 LATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAW 540
Query: 541 QSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTG 600
QSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTG
Sbjct: 541 QSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTG 600
Query: 601 LSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQ 660
LSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQ
Sbjct: 601 LSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQ 660
Query: 661 LKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRP 720
LKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRP
Sbjct: 661 LKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRP 720
Query: 721 REGLWSHVDQLNRTLAQHTQDIARLRDDLLDCQAQLAEQVRPGQAN 766
REGLWSHVDQLNRTLAQHTQDIARLRDDLLDCQAQLAEQVRPGQAN
Sbjct: 721 REGLWSHVDQLNRTLAQHTQDIARLRDDLLDCQAQLAEQVRPGQAN 766
>gi|60498978 elastin microfibril interfacer 2 [Homo sapiens]
Length = 1053
Score = 223 bits (569), Expect = 4e-58
Identities = 206/794 (25%), Positives = 361/794 (45%), Gaps = 99/794 (12%)
Query: 9 WLCAVAALLSGAQARGTPLLARPAPPGASRYSLYTTGWRPRLRPGPHKALCAYVVHRNVT 68
W A+ AL+ P PA P A +K CAY+V++NV+
Sbjct: 15 WALALLALVGAGLCHAGPQPGYPARPSAR-----------------NKNWCAYIVNKNVS 57
Query: 69 CILQEGAESYVKAEYRQCRWGPK-CPGTVTYRTVLRPKYKVGYKTVTDLAWRCCPGFTGK 127
C + EG+ES+++A+Y C W CP + YR RP+Y YKTVT L WRCCPGF G
Sbjct: 58 CSVLEGSESFIQAQYN-CAWNQMPCPSALVYRVNFRPRYVTRYKTVTQLEWRCCPGFRGG 116
Query: 128 RCPEHLTDHGAASPQLEPEPQIPSGQL----DPGPRPPSYSRAAPSPHG----------R 173
C E D L P P P L D P S R SP G +
Sbjct: 117 DCQEGPKD---PVKTLRPTPARPRNSLKKATDNEPSQFSEPRKTLSPTGTAQPSWGVDPK 173
Query: 174 KGP-GLFGERLERLEGDVQRLAQT----YGTLSGLV-----ASHEDPNRMTGGPRAPAVP 223
+GP L ++++ LE V RL +T +L+G+ A+ +D +R RAP +
Sbjct: 174 EGPQELQEKKIQVLEEKVLRLTRTVLDLQSSLAGVSENLKHATQDDASR----TRAPGLS 229
Query: 224 VGFGVIPEGLVGPGDRARGP-----LTPPLDEILSKVTEVSNTLQTKVQLLDKVHGLALG 278
+ G + + P + +I S++ EV +TL+ K L+++ G G
Sbjct: 230 SQHPKPDTTVSGDTETGQSPGVFNTKESGMKDIKSELAEVKDTLKNKSDKLEELDGKVKG 289
Query: 279 HEAHLQRLREAPPSP---LTSLALLEEYVDRRLHRLWGSLLDGFEQKLQGVQSECDLRVQ 335
+E L++L+EA P +T+ L + YVD ++ L L++G ++KL +++ C+ ++
Sbjct: 290 YEGQLRQLQEAAQGPTVTMTTNELYQAYVDSKIDALREELMEGMDRKLADLKNSCEYKLT 349
Query: 336 EVRRQCEEGQAASRRLHQSLDGRELALRQELSQLGSQLQGLSVSGRGSCCG--QLALINA 393
+++QC++ ++ + + + +E +LR+E++ L ++LQ S + +CC + I
Sbjct: 350 GLQQQCDDYGSSYLGVIELIGEKETSLRKEINNLRARLQ--EPSAQANCCDSEKNGDIGQ 407
Query: 394 RMDGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGLLEGLET-LNGTEGGARGC 452
++ L++ ++ V E R +E RL + D L+ +N TE A
Sbjct: 408 QIKTLDQKIERVAEATRMLNGRLDNEFDRLIVPEPDVDFDAKWNELDARINVTEKNAEEH 467
Query: 453 CLRLDMGGWG-----VGGFGTMLEERVQSLEERLATLAGELSHDSAS----PGRSARPLV 503
C ++ G VG ++++++QSLE+RL ++ ++++++ + PG +A P V
Sbjct: 468 CFYIEETLRGAINGEVGDLKQLVDQKIQSLEDRLGSVLLQMTNNTGAELSPPGAAALPGV 527
Query: 504 QTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALL-----RQVASHAALL 558
V +E + + D + ++ E L R V LL
Sbjct: 528 SGS----GDERVMMELNHLKDKVQVVEDICLLNIQGKPHGMEGALPNREDRAVRDSLHLL 583
Query: 559 QQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQY---SDAFLAA 615
+ LN T+ + Q E T LQ + + L LN +T L +S +A +
Sbjct: 584 KSLNDTMHR-KFQETEQTIQKLQQDFSFLYSQLNHTENDVTHLQKEMSNCRAGENAGMGR 642
Query: 616 NTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRC 675
T + E+ER V+ + + Q V+ S+L+ E+ + ++V S L C
Sbjct: 643 FTKVGEQERTVDT-LPSPQHPVAHCCSQLE-------------ERWQRLQSQVISELDAC 688
Query: 676 QDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTL 735
++ Q +Q V + RV+ +E C +L ++ L + + LW+ V Q+N TL
Sbjct: 689 KECTQGVQREVSMVEGRVSHMEKTCSKLDSISGNLQRIKEGLNKHVSSLWNCVRQMNGTL 748
Query: 736 AQHTQDIARLRDDL 749
H++DI+ L++ +
Sbjct: 749 RSHSRDISGLKNSV 762
>gi|5901944 elastin microfibril interfacer 1 [Homo sapiens]
Length = 1016
Score = 166 bits (420), Expect = 8e-41
Identities = 235/867 (27%), Positives = 339/867 (39%), Gaps = 196/867 (22%)
Query: 8 VWLCAVAALLSGAQARGTPLLARPAPPGASRYS-----LYTTGWRPRLRPGP---HKALC 59
+W C + LL+ A A P G S Y+ L G + ++ P P H+ C
Sbjct: 6 LWSCYLCCLLTAAAGA-----ASYPPRGFSLYTGSSGALSPGGPQAQIAPRPASRHRNWC 60
Query: 60 AYVVHRNVTCILQEGAESYVKAEYRQCRWG-PKCPGTVTYRTVLRPKYKVGYKTVTDLAW 118
AYVV R V+C+L++G E+YVK Y+ C WG P+CP ++ YR LRP+Y+V YKTVTD+ W
Sbjct: 61 AYVVTRTVSCVLEDGVETYVK--YQPCAWGQPQCPQSIMYRRFLRPRYRVAYKTVTDMEW 118
Query: 119 RCCPGFTGKRCPEHLTDHGAASPQLEPEPQIPSGQLDPGPRPPSYSRAAPSP---HGRKG 175
RCC G+ G C E + +P L P P P RP +A SP G +G
Sbjct: 119 RCCQGYGGDDCAE------SPAPALGPASSTPRPLARPA-RPNLSGSSAGSPLSGLGGEG 171
Query: 176 PGLFGERLERLEGDVQRLAQTYGTLSGLVASHEDPNRMTGGPRAPAVPVGFGVIPEGLVG 235
PG E++++LE VQ L + L G++ G A V G
Sbjct: 172 PG-ESEKVQQLEEQVQSLTKELQGLRGVLQG-------LSGRLAEDVQRAVETAFNGRQQ 223
Query: 236 PGDRARGPLTPPLDEILSKVTEVSNTLQTKVQLLD---KVHGLALGH------------E 280
P D A P V E N +Q ++QLLD H LGH
Sbjct: 224 PADAAARP----------GVHETLNEIQHQLQLLDTRVSTHDQELGHLNNHHGGSSSSGG 273
Query: 281 AHLQRLREAPPSPLTSLALLEEYVDRRLHRLWGSLLDGFEQKLQGVQSECDLRVQEVRRQ 340
+ APP P LL EQ+LQ S C + RRQ
Sbjct: 274 SRAPAPASAPPGPSE------------------ELLRQLEQRLQESCSVCLAGLDGFRRQ 315
Query: 341 CEEGQAASRRLHQSLDGRELALRQELSQLGSQLQGLSVSGR--GSCCG-----QLALINA 393
+E + R + + L E R L GL+V R CC +LA +
Sbjct: 316 QQEDRERLRAMEKLLASVEERQR--------HLAGLAVGRRPPQECCSPELGRRLAELER 367
Query: 394 RMD---GLERALQAVTETQRGPGAPAGDE---LTRLSAAM--LEGGVDGLL----EGLET 441
R+D G L T+ G A G T L++ + LE + L E E+
Sbjct: 368 RLDVVAGSVTVLSGRRGTELGGAAGQGGHPPGYTSLASRLSRLEDRFNSTLGPSEEQEES 427
Query: 442 LNGTEGG-------ARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLA---TLAGELSHD 491
G GG ARG RL+ G + L R+ LEE++A G+L
Sbjct: 428 WPGAPGGLSHWLPAARG---RLEQLGGLLANVSGELGGRLDLLEEQVAGAMQACGQLC-- 482
Query: 492 SASPGRSARPLVQTELAVLEQRLVSLE------------TSCTPSTTSAILDSLVAEVKA 539
S +PG V L+ LE+R++ E A L+ L V
Sbjct: 483 SGAPGEQDSQ-VSEILSALERRVLDSEGQLRLVGSGLHTVEAAGEARQATLEGLQEVVGR 541
Query: 540 WQSRSEALLRQVASH-------AALLQQLNGT--------------VAEVQGQLAE---- 574
Q R +A A AA L QL G V E G+L +
Sbjct: 542 LQDRVDAQDETAAEFTLRLNLTAARLGQLEGLLQAHGDEGCGACGGVQEELGRLRDGVER 601
Query: 575 ---------------GTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSL 619
G G +G + V S +L L +S+ +F + N SL
Sbjct: 602 CSCPLLPPRGPGAGPGVGGPSRGPLDGFSVFGGSSGSALQALQGELSEVILSFSSLNDSL 661
Query: 620 DERERKVE------AEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLS 673
+E + VE A++ A ++++ S+ +RLQ ++ E E+ G+ + +
Sbjct: 662 NELQTTVEGQGADLADLGATKDRIISEINRLQ---QEATEHATESEERFRGLEEGQAQAG 718
Query: 674 RCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNR 733
+C + R+ ++EG C RL +A GL L R GLW+ + + N
Sbjct: 719 QCPS-----------LEGRLGRLEGVCERLDTVAGGLQGLREGLSRHVAGLWAGLRETNT 767
Query: 734 TLAQHTQDIARLRDDLLDCQAQLAEQV 760
T +Q A L + L+ QA L ++
Sbjct: 768 T----SQMQAALLEKLVGGQAGLGRRL 790
>gi|118498339 EMI domain containing 2 [Homo sapiens]
Length = 439
Score = 89.4 bits (220), Expect = 1e-17
Identities = 67/204 (32%), Positives = 87/204 (42%), Gaps = 42/204 (20%)
Query: 59 CAYVVHRNVTCILQEGAESYVKAEYRQCRWGPKCPGTVTYRTVLRPKYKVGYKTVTDLAW 118
C + V R V+C +Q G+E+ V+ Y+ CRW C V RT++RP Y+V Y+TVT L W
Sbjct: 56 CHHTVTRTVSCQVQNGSETVVQRVYQSCRWPGPCANLV--RTLIRPTYRVSYRTVTVLEW 113
Query: 119 RCCPGFTGKRCPE------HLTDHGAASPQLEPEPQIPSGQLDPGPRPPSYSRAAPSPHG 172
RCCPGFTG C E L+D LE + + L+ RP S P+P
Sbjct: 114 RCCPGFTGSNCDEECMNCTRLSDMSERLTTLEAKVLL----LEAAERPSSPDNDLPAPES 169
Query: 173 RKGPGLFGERLERLEGDVQRLAQTYGTLSGLVASHEDP-NRMTGGPRAPAVPVGFGVIPE 231
P + E + +H P R GP P G P
Sbjct: 170 T--PPTWNEDF---------------LPDAIPLAHPVPRQRRPTGPAGPPGQTG----PP 208
Query: 232 GLVGP----GDRA----RGPLTPP 247
G GP GDR +GP PP
Sbjct: 209 GPAGPPGSKGDRGQTGEKGPAGPP 232
>gi|50511941 EMI domain containing 1 [Homo sapiens]
Length = 443
Score = 88.2 bits (217), Expect = 3e-17
Identities = 69/195 (35%), Positives = 94/195 (48%), Gaps = 21/195 (10%)
Query: 59 CAYVVHRNVTCILQEGAESYVKAEYRQCRWGPKCPGTVTYRTVLRPKYKVGYKTVTDLAW 118
C+YVV R ++C +Q G +Y++ + C W CPG+ +YRTV+RP YKV YK VT W
Sbjct: 37 CSYVVTRTISCHVQNG--TYLQRVLQNCPWPMSCPGS-SYRTVVRPTYKVMYKIVTAREW 93
Query: 119 RCCPGFTGKRCPEHLTDHGAASPQLEPEPQIPSGQLDPGPRPPSYSRAAPSPHGRKGPGL 178
RCCPG +G C E A+S LEP S RP ++S +
Sbjct: 94 RCCPGHSGVSCEE----VAASSASLEP-MWSGSTMRRMALRPTAFSGCLNCSKVSE---- 144
Query: 179 FGERLERLEGDVQRLAQTYGTLSGLVASHEDPNRMTGGPRAPAVPVGFGVIPE----GLV 234
ERL+ LE + L + A+ EDP + G P A P G+ + GL
Sbjct: 145 LTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLWGPPPAQGSPGDGGLQDQVGAWGLP 204
Query: 235 GP----GDR-ARGPL 244
GP GD +RGP+
Sbjct: 205 GPTGPKGDAGSRGPM 219
>gi|221316695 multimerin 2 precursor [Homo sapiens]
Length = 949
Score = 63.5 bits (153), Expect = 7e-10
Identities = 151/703 (21%), Positives = 247/703 (35%), Gaps = 126/703 (17%)
Query: 20 AQARGTPL--LARPAPPGASRYSLYTTGWRPRLRPGPHKALCAYVVHRNVTCILQEGAES 77
AQA T L L PG + TG P R C Y + + VT + E
Sbjct: 22 AQASSTSLSDLQSSRTPGVWKAEAEDTGKDPVGRNW-----CPYPMSKLVTLLALCKTEK 76
Query: 78 YVKAEYRQCRWG-PKCPGT-VTYRTVLRPKYKVGYKTVTDLAWRCCPGFTGKRCPEHLTD 135
++ + C G P C V YR +P Y+V K +T LAWRCCPG+TG C H
Sbjct: 77 FLIHSQQPCPQGAPDCQKVKVMYRMAHKPVYQVKQKVLTSLAWRCCPGYTGPNCEHH--- 133
Query: 136 HGAASPQLEPEPQIP-SGQLDPGPRPPSYSRAAPSPHGRKGPGLFGERLERLEGDVQRLA 194
PEP P +P P S+ PG + +E ++
Sbjct: 134 ----DSMAIPEPADPGDSHQEPQDGPVSFK-----------PGHLAAVINEVEVQQEQQE 178
Query: 195 QTYGTLSGLVASHEDPNRMTGGPRAPAVPVGFGVIPEGLVG---PGDRARGPLTPPLDEI 251
G L V H + + G +A + V+ G P L P +D
Sbjct: 179 HLLGDLQNDV--HRVADSLPGLWKALPGNLTAAVMEANQTGHEFPDRSLEQVLLPHVDTF 236
Query: 252 L----SKVTEVSNTLQTKVQLLDKVHGLALGHEAHLQRLREAPPSPLTSLALLEEYVDRR 307
L S + N Q+ L + L+L EA+ Q + S + E
Sbjct: 237 LQVHFSPIWRSFN--QSLHSLTQAIRNLSLDVEANRQAISRVQDSAVARADFQE------ 288
Query: 308 LHRLWGSLLDGFEQKLQGVQSECDLRVQEVRRQCEEGQAASR-RLHQSLDGRELALRQEL 366
L FE K+Q E RV ++R+ E+ A LH+S+ + + +L
Sbjct: 289 -------LGAKFEAKVQ----ENTQRVGQLRQDVEDRLHAQHFTLHRSISELQADVDTKL 337
Query: 367 SQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAA 426
+L + +G +L+ A PGA A E L A
Sbjct: 338 KRLHKAQEAPGTNG--------SLVLAT-----------------PGAGARPEPDSLQAR 372
Query: 427 MLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAG 486
+ + L L L+ T EE +LE+ ATL
Sbjct: 373 LGQ-----LQRNLSELHMTTARRE--------------------EELQYTLEDMRATLTR 407
Query: 487 ELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEA 546
+ D S +++ +E+++ L+ + T ++ L+ + + E
Sbjct: 408 HV--DEIKELYSESDETFDQISKVERQVEELQVNHTALRELRVI--LMEKSLIMEENKEE 463
Query: 547 LLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVS 606
+ RQ+ LQ L G A++ + + L ++ +++ +++L
Sbjct: 464 VERQLLELNLTLQHLQGGHADLIKYVKDCNCQKLYLDLDVIREGQRDATRALE------- 516
Query: 607 QYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVA 666
SLDER + + +QA+Q V + + A + R +L++ V
Sbjct: 517 -------ETQVSLDERRQLDGSSLQALQNAVDAVSLAVDAHKAEGERARAATSRLRSQVQ 569
Query: 667 KVASGLSRCQDTAQKLQHTVGHFDQR-VAQVEGACRRLGLLAA 708
+ + + A + +H V A +E A R +LAA
Sbjct: 570 ALDDEVGALKAAAAEARHEVRQLHSAFAALLEDALRHEAVLAA 612
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 57.8 bits (138), Expect = 4e-08
Identities = 66/255 (25%), Positives = 107/255 (41%), Gaps = 33/255 (12%)
Query: 535 AEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLA--EGTGSSLQGEITLLKVNLN 592
A+ +A Q R ++L RQVA L TV + G LA E + +L+ ++ L L
Sbjct: 1677 AQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALA 1736
Query: 593 SVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQE---QVSSQGSRLQAGHR 649
S SL D A A + +++A QA+ E Q SS G ++Q
Sbjct: 1737 QSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRG 1796
Query: 650 QVLNLR-------GELEQLK-------AGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQ 695
+V +L G+L+QL+ G A + + + QD + LQ +G + +AQ
Sbjct: 1797 EVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQ 1856
Query: 696 VEGACRRLG-----------LLAAGLDSLPTEPLRPREG---LWSHVDQLNRTLAQHTQD 741
+E R + L LD + E LR E L + +L+RTL +
Sbjct: 1857 LEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELE 1916
Query: 742 IARLRDDLLDCQAQL 756
+A + + +AQ+
Sbjct: 1917 LAEAQRQIQQLEAQV 1931
Score = 48.5 bits (114), Expect = 2e-05
Identities = 102/466 (21%), Positives = 169/466 (36%), Gaps = 87/466 (18%)
Query: 320 EQKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGRELAL---RQELSQLGSQLQGL 376
++KLQ + E R + + EE + ++ G EL L R E ++LG +L
Sbjct: 1349 QRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAA 1408
Query: 377 SVSGRGSCCGQLALIN-------ARMDGLERALQAVTETQRGP--------GAPAGDELT 421
+G +LA + A++ GL AL+ R P G+PA D
Sbjct: 1409 EGRAQG-LEAELARVEVQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRPVPGSPARD--- 1464
Query: 422 RLSAAMLEGGVDGLLEG--LETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEE 479
A EG +GL LE G++ + G L E +Q L
Sbjct: 1465 ----APAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRS 1520
Query: 480 RLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKA 539
+ R ++T+ + L ++L +E AE +
Sbjct: 1521 ----------------AQRERDELRTQTSALNRQLAEME----------------AERDS 1548
Query: 540 WQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGE---------ITLLKVN 590
SR+ L + VA + ++G ++ VQ +LA S + E + L+ +
Sbjct: 1549 ATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERS 1608
Query: 591 LNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQ 650
L + L + +S+ + E K+E + + ++E + + SR Q
Sbjct: 1609 LQATESELRASQEKISK-----------MKANETKLEGDKRRLKEVLDASESRTVKLELQ 1657
Query: 651 VLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGL 710
+L GEL++ + GLS + AQ LQ V ++VA E L L L
Sbjct: 1658 RRSLEGELQRSRL-------GLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERL 1710
Query: 711 DSLPTEPLRPREGLWSHVDQLNRTLAQHTQDIARLRDDLLDCQAQL 756
+ + L V L LAQ + + RD L Q L
Sbjct: 1711 NGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKAL 1756
Score = 41.6 bits (96), Expect = 0.003
Identities = 119/536 (22%), Positives = 199/536 (37%), Gaps = 100/536 (18%)
Query: 262 LQTKVQLLDKVHGLALGHE-AHLQR-LREAPPSPLTSLALLEEYVDRRLHRLWGSLLDGF 319
L ++V++ + L LG E A R ++EA T L L E + L +
Sbjct: 309 LVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEK--------- 359
Query: 320 EQKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGRELALRQELSQLGSQLQGLSVS 379
Q L Q E LR + +R E A +++ LD +L+ R +++LG ++ L
Sbjct: 360 -QALLQAQLEEQLRDKVLR----EKDLAQQQMQSDLDKADLSAR--VTELGLAVKRLEKQ 412
Query: 380 G--RGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGL-L 436
+ L ++ L QA ET+ G G L L+ A+L G+ L
Sbjct: 413 NLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQ--QTLRDLAQAVLSDSESGVQL 470
Query: 437 EGLE-TLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHDSASP 495
G E T + + G RG + +R S R +SP
Sbjct: 471 SGSERTADASNGSLRG-----------------LSGQRTPSPPRR------------SSP 501
Query: 496 GRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSL-------VAEVKAWQSRSEALL 548
GR P A C+ S+T A++ S V +++ S+ LL
Sbjct: 502 GRGRSPRRGPSPA------------CSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLL 549
Query: 549 RQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQG------EITLLKVNLNSVSKSLTGLS 602
+ + + + E +L + T ++Q E+ L+ +S+ + L+
Sbjct: 550 GTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLA 609
Query: 603 DSVS----------QYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSR----LQAGH 648
S+ Q + AA L + ++E E QE G+R L+ H
Sbjct: 610 HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEE----QEDAVQDGARVRRELERSH 665
Query: 649 RQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAA 708
RQ+ L G+ L + +V LSR LQ + + + E L L
Sbjct: 666 RQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELEL--- 722
Query: 709 GLDSLPTEPLRPREGLWSHVDQLNRTLAQHTQDIARLRDDLLDCQAQLAEQVRPGQ 764
+ L E ++ L S + LN +LAQ D+ RL L + ++ L + R +
Sbjct: 723 SMTKLRAEEASLQDSL-SKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAE 777
Score = 41.6 bits (96), Expect = 0.003
Identities = 118/551 (21%), Positives = 210/551 (38%), Gaps = 74/551 (13%)
Query: 156 PGPRPPSYSRAAPSPHGRKGPGLFGERLERLEGDVQRLAQTYGTLSGLVASHEDPNRMTG 215
P PRP S A +P G GL LE + G + + DP + G
Sbjct: 1452 PAPRPVPGSPARDAPAEGSGEGL--NSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRG 1509
Query: 216 GPRAPAVPVGFGVIPEGLVGPGDRARGPL---TPPLDEILSKVTEVSNTLQTKVQLLDKV 272
R + E + R R L T L+ L+++ ++ ++ + L K
Sbjct: 1510 ALRE--------FLQE--LRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQK- 1558
Query: 273 HGLALGHEAHLQRLREAPPSPLTSLALLEEYVDRRLHRLWGSLLD---GFEQKLQGVQSE 329
A+ +R + S + + L+E RR R + LD E+ LQ +SE
Sbjct: 1559 ---AVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESE 1615
Query: 330 ---CDLRVQEVRRQCEEGQAASRRLHQSLD---GRELALRQELSQLGSQLQ--GLSVSGR 381
++ +++ + + RRL + LD R + L + L +LQ L +S R
Sbjct: 1616 LRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDR 1675
Query: 382 GSCCGQLALINARMDGLER----------ALQAVTETQRGPGAPAGDELTRLSAAMLEGG 431
+ Q + R+D L+R LQ E G A + S L
Sbjct: 1676 EA---QAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEE-----SEGALRDK 1727
Query: 432 VDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHD 491
V GL E L + + R L L +L+ER+ + + L+ E
Sbjct: 1728 VRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALS----EARKQ 1783
Query: 492 SASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQV 551
S+S G + L + E+A LE + V E L ++ + + ++ + ++++
Sbjct: 1784 SSSLGEQVQTL-RGEVADLELQRVEAEGQLQQ------LREVLRQRQEGEAAALNTVQKL 1836
Query: 552 ASHAALLQQLNGTVAEVQGQL------AEGTGSSLQGEITLLKVNLNSVSK-------SL 598
LLQ+ G++ QL E + L+ + L+ L+ V +
Sbjct: 1837 QDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDT 1896
Query: 599 TGLSDSVSQYSDAFLAANTSLDERERKV-EAEVQAIQEQVSSQGSRLQA-GHRQVLNLRG 656
LS + A L E +R++ + E Q + + S ++L+ +Q L L+
Sbjct: 1897 VRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQ 1956
Query: 657 ELEQLKAGVAK 667
E+E+L++ A+
Sbjct: 1957 EVERLRSAQAQ 1967
Score = 37.4 bits (85), Expect = 0.053
Identities = 126/584 (21%), Positives = 196/584 (33%), Gaps = 97/584 (16%)
Query: 119 RCCPGFTGKRCPEHLTDHGAASPQ-LEPEPQIPSGQLDPGPRPPSYSRAAPS--PHGRKG 175
R PG + P + G SP LE P G P P P + S A+P P +G
Sbjct: 1455 RPVPGSPARDAPAEGSGEGLNSPSTLECSP----GSQPPSPGPAT-SPASPDLDPEAVRG 1509
Query: 176 P----------------------GLFGERLERLEGDVQRLAQTYGTLSGLVASHEDPNRM 213
+L +E + L VA E+ R
Sbjct: 1510 ALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRS 1569
Query: 214 TGGPRAPAVPVGFGVIPEGLVGPGDRARGPL--TPPLDEILSKVTEVSNTLQTKVQLLDK 271
G R V + E + R L L+ L Q K+ +
Sbjct: 1570 VDG-RLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKA 1628
Query: 272 VHGLALGHEAHLQRLREAPPSPLTSLALLEEYVDRRLHRLWGSLLDGFEQKLQGVQSECD 331
G + L+ + +A S L L ++ L R L D E + Q +Q D
Sbjct: 1629 NETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDR-EAQAQALQDRVD 1687
Query: 332 -LRVQEVRRQCEEG--QAASRRLHQSL---DGRELALRQELSQLGSQLQGLSVSGRGS-- 383
L+ Q + + G Q RL+ +L + E ALR ++ L L S S +
Sbjct: 1688 SLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRD 1747
Query: 384 -----------CCGQLALINARMDGLERALQAVT--------ETQRGPGAPAGDELTRLS 424
C ++ R+D +AL + Q G A EL R+
Sbjct: 1748 KNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVE 1807
Query: 425 AAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATL 484
A EG + L E L E A +L +L+ER+ SL+ LA L
Sbjct: 1808 A---EGQLQQLREVLRQRQEGEAAALNTVQKLQ-------DERRLLQERLGSLQRALAQL 1857
Query: 485 AGELSHDSASPGRSARPLV---QTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQ 541
E S R + V +T V ++L S E + S LD + +
Sbjct: 1858 EAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELEL 1917
Query: 542 SRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGL 601
+ ++ ++Q+ + +L+Q + S Q E+ + L L
Sbjct: 1918 AEAQRQIQQLEAQVVVLEQSH---------------SPAQLEVDAQQQQLE--------L 1954
Query: 602 SDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQ 645
V + A +L+ RER V+ ++EQVS+ +LQ
Sbjct: 1955 QQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQVSTLKGQLQ 1998
Score = 30.0 bits (66), Expect = 8.4
Identities = 39/201 (19%), Positives = 81/201 (40%), Gaps = 15/201 (7%)
Query: 475 QSLEERLATLAGELSHDS----ASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAIL 530
+ LE+ L GEL R +Q E A ++L + + + ++
Sbjct: 116 ERLEQALRLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEG--QQRQAQLV 173
Query: 531 DSLVAEVKAWQSRSEALLRQVASHAALLQQ--LNGTV-------AEVQGQLAEGTGSSLQ 581
L ++ ++ R L +Q+ + L+Q L T A ++ + + +SL
Sbjct: 174 QRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLA 233
Query: 582 GEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQG 641
+L+ L+ + LS+ + + ++ + L+ RE E ++ S++
Sbjct: 234 QVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEH 293
Query: 642 SRLQAGHRQVLNLRGELEQLK 662
SRL RQV+ R + ++K
Sbjct: 294 SRLLLLWRQVVGFRRLVSEVK 314
>gi|45269141 multimerin 1 [Homo sapiens]
Length = 1228
Score = 54.7 bits (130), Expect = 3e-07
Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
Query: 56 KALCAYVVHRNVTCILQEGAESYVKAEYRQCRW-GPKCPGTVTYRTVLRPKYKVGYKTVT 114
K CAYV R ++ + +YV C W G CP + + P Y++ +K VT
Sbjct: 208 KNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGWTGGSCPQRS--QKISNPVYRMQHKIVT 265
Query: 115 DLAWRCCPGFTGKRC 129
L WRCCPG++G +C
Sbjct: 266 SLDWRCCPGYSGPKC 280
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 53.5 bits (127), Expect = 7e-07
Identities = 116/518 (22%), Positives = 194/518 (37%), Gaps = 93/518 (17%)
Query: 241 RGPLTPPLD------EILSK----VTEVSNTLQTK-------VQLLDKVHGLALGH---- 279
RG L LD E+ SK VTE+ TL+ + VQ L + HG ALG
Sbjct: 1177 RGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQ 1236
Query: 280 ------------------EAHLQRLREAPPSPLTSLALLEEYVDRRLHRL-------WGS 314
EA + LR + L+SL + ++R RL G
Sbjct: 1237 LEQARRGKGAWEKTRLALEAEVSELR----AELSSLQTARQEGEQRRRRLELQLQEVQGR 1292
Query: 315 LLDGFE------QKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGRELALR--QEL 366
DG +KLQ Q+E ++ V E ++ + RL + L E L QEL
Sbjct: 1293 AGDGERARAEAAEKLQRAQAE----LENVSGALNEAESKTIRLSKELSSTEAQLHDAQEL 1348
Query: 367 SQ--------LGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVT---------ETQ 409
Q LGS+++ + G QL A + R LQ + +
Sbjct: 1349 LQEETRAKLALGSRVRAMEAEAAG-LREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1407
Query: 410 RGPGAPAGDELTRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTM 469
AG+E R +A E L E ET++ E G R LD +
Sbjct: 1408 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL----EQ 1463
Query: 470 LEERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAI 529
+ V +LE++ L+ + A+ R+ + E E+ +L +
Sbjct: 1464 QRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEA 1523
Query: 530 LDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKV 589
+ L + +A ++ EALL + +L E ++AE + L+ ++T L+
Sbjct: 1524 REELERQNRALRAELEALLSSKDDVGKSVHEL-----ERACRVAEQAANDLRAQVTELED 1578
Query: 590 NLNSVSKSLTGLSDSV----SQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQ 645
L + + L +V +Q+ + + +ER R++ +++ + + + +
Sbjct: 1579 ELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1638
Query: 646 AGHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQ 683
L GELE+LKA +A G +K+Q
Sbjct: 1639 LAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQ 1676
Score = 52.4 bits (124), Expect = 2e-06
Identities = 100/442 (22%), Positives = 169/442 (38%), Gaps = 46/442 (10%)
Query: 339 RQCEEGQAASRRLHQSLDGRELALRQELSQLGSQLQGLSVS-GRGSCCGQLALINARMDG 397
R+ E+G+ +L + LDG L++++ + + + L GR Q AL A +G
Sbjct: 1069 RKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG 1128
Query: 398 LERA--LQAVTETQRGPGAPAGD-ELTRLSAAMLEGGVDGLLEGLETLNGT-EGGARGCC 453
RA L+++ E Q D E R++ E L E LE L G E
Sbjct: 1129 GARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTN 1188
Query: 454 LRLDMGG---WGVGGFGTMLEER-------VQSLEERLATLAGELSH--DSASPGRSA-- 499
+ ++ V LEE VQ L +R GEL+ + A G+ A
Sbjct: 1189 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1248
Query: 500 --RPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQVASHAAL 557
R ++ E++ L L SL+T+ L +++ Q R+ R A A
Sbjct: 1249 KTRLALEAEVSELRAELSSLQTARQEGEQRR--RRLELQLQEVQGRAGDGERARAEAAEK 1306
Query: 558 LQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANT 617
LQ+ + V G L E +++ L L+S L + + + + A LA
Sbjct: 1307 LQRAQAELENVSGALNEAESKTIR-----LSKELSSTEAQLHDAQELLQEETRAKLA--- 1358
Query: 618 SLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQD 677
L R R +EAE ++EQ+ + + + R++ + +L + + + A L ++
Sbjct: 1359 -LGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEE 1417
Query: 678 TAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQ 737
++ QR+A+ RL R R L +D L Q
Sbjct: 1418 ARRRAAREAEALTQRLAEKTETVDRLE--------------RGRRRLQQELDDATMDLEQ 1463
Query: 738 HTQDIARLRDDLLDCQAQLAEQ 759
Q ++ L LAE+
Sbjct: 1464 QRQLVSTLEKKQRKFDQLLAEE 1485
Score = 35.4 bits (80), Expect = 0.20
Identities = 114/546 (20%), Positives = 205/546 (37%), Gaps = 66/546 (12%)
Query: 250 EILSKVTEVSNTLQTKVQLLD-KVHGLALGHEAHLQRLREAPPSPLTSLALLEEYVDRRL 308
E+L + T L ++V+ ++ + GL E A T+ A L E+ RR
Sbjct: 1347 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW-RRRQ 1405
Query: 309 HRLWGSLLDGFEQKLQGVQSECDL--RVQEVRRQCEEGQAASRRLHQSLDGRELALRQEL 366
G+L G E + + + L R+ E + + RRL Q LD + L Q+
Sbjct: 1406 EEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQ- 1464
Query: 367 SQLGSQLQGLSVSGRGSCCGQLALI--------NARMDGLERALQAVTETQR-GPGAPAG 417
QL S L+ + A + A +G ER +A++ T+ A
Sbjct: 1465 RQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAR 1524
Query: 418 DELTRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSL 477
+EL R + A L ++ LL + + + C + + T LE+ + +
Sbjct: 1525 EELERQNRA-LRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAA 1583
Query: 478 EERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEV 537
E+ L + A + R L + A E+R + D AEV
Sbjct: 1584 EDAKLRLEVTVQ---ALKTQHERDLQGRDEAGEERRR---------QLAKQLRD---AEV 1628
Query: 538 KAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKS 597
+ + R + L A ++L G + E++ Q+A G + + L+ + + K
Sbjct: 1629 ERDEERKQRTLAVAAR-----KKLEGELEELKAQMASA-GQGKEEAVKQLR-KMQAQMKE 1681
Query: 598 LTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQV-SSQGSRLQA---------- 646
L + + + N ++R + +EAEV +QE++ +S +R QA
Sbjct: 1682 LWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE 1741
Query: 647 ---GHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRL 703
G+ + E QL+ + ++ L Q ++ L + + + QVE L
Sbjct: 1742 VANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLN---DRYRKLLLQVESLTTEL 1798
Query: 704 GLLAAGLDSLPTEPLRPREGLWSHVDQLNRTL--------AQHTQDIARLRDDLLDCQAQ 755
+ S + R+ L + +L L A+H IA L L + Q
Sbjct: 1799 ----SAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQ 1854
Query: 756 LAEQVR 761
L ++ R
Sbjct: 1855 LEQETR 1860
Score = 31.2 bits (69), Expect = 3.8
Identities = 77/364 (21%), Positives = 133/364 (36%), Gaps = 77/364 (21%)
Query: 472 ERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILD 531
++VQ L+++ A GEL A L + A E + ET + L+
Sbjct: 887 QKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELE 946
Query: 532 SLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLA--EGTGSSLQGE------ 583
+V+E++A E RQ+ + LQQ + E++ L EG LQ E
Sbjct: 947 LVVSELEARVGEEEECSRQMQTEKKRLQQ---HIQELEAHLEAEEGARQKLQLEKVTTEA 1003
Query: 584 --------ITLLKVNLNSVSKSLTGLSDSVSQYS--------------------DAFLA- 614
+ LL+ + +SK L D ++++S +A +A
Sbjct: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063
Query: 615 ----------ANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAG 664
L++ +R+++ E +QEQ+ Q R + Q+ EL+ A
Sbjct: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123
Query: 665 V-------AKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRR----------LGLLA 707
A++ L Q + Q + +RVA+ + +R G L
Sbjct: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLE--SERVARTKAEKQRRDLGEELEALRGELE 1181
Query: 708 AGLDSLPTEPLRPREGLWSHVDQLNRTLAQHT-------QDIARLRDDLLDCQAQLAEQV 760
LDS + R V +L +TL + T Q++ + L A+ EQ
Sbjct: 1182 DTLDSTNAQQ-ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQA 1240
Query: 761 RPGQ 764
R G+
Sbjct: 1241 RRGK 1244
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 53.5 bits (127), Expect = 7e-07
Identities = 116/518 (22%), Positives = 194/518 (37%), Gaps = 93/518 (17%)
Query: 241 RGPLTPPLD------EILSK----VTEVSNTLQTK-------VQLLDKVHGLALGH---- 279
RG L LD E+ SK VTE+ TL+ + VQ L + HG ALG
Sbjct: 1169 RGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQ 1228
Query: 280 ------------------EAHLQRLREAPPSPLTSLALLEEYVDRRLHRL-------WGS 314
EA + LR + L+SL + ++R RL G
Sbjct: 1229 LEQARRGKGAWEKTRLALEAEVSELR----AELSSLQTARQEGEQRRRRLELQLQEVQGR 1284
Query: 315 LLDGFE------QKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGRELALR--QEL 366
DG +KLQ Q+E ++ V E ++ + RL + L E L QEL
Sbjct: 1285 AGDGERARAEAAEKLQRAQAE----LENVSGALNEAESKTIRLSKELSSTEAQLHDAQEL 1340
Query: 367 SQ--------LGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVT---------ETQ 409
Q LGS+++ + G QL A + R LQ + +
Sbjct: 1341 LQEETRAKLALGSRVRAMEAEAAG-LREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1399
Query: 410 RGPGAPAGDELTRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTM 469
AG+E R +A E L E ET++ E G R LD +
Sbjct: 1400 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL----EQ 1455
Query: 470 LEERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAI 529
+ V +LE++ L+ + A+ R+ + E E+ +L +
Sbjct: 1456 QRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEA 1515
Query: 530 LDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKV 589
+ L + +A ++ EALL + +L E ++AE + L+ ++T L+
Sbjct: 1516 REELERQNRALRAELEALLSSKDDVGKSVHEL-----ERACRVAEQAANDLRAQVTELED 1570
Query: 590 NLNSVSKSLTGLSDSV----SQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQ 645
L + + L +V +Q+ + + +ER R++ +++ + + + +
Sbjct: 1571 ELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1630
Query: 646 AGHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQ 683
L GELE+LKA +A G +K+Q
Sbjct: 1631 LAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQ 1668
Score = 52.4 bits (124), Expect = 2e-06
Identities = 100/442 (22%), Positives = 169/442 (38%), Gaps = 46/442 (10%)
Query: 339 RQCEEGQAASRRLHQSLDGRELALRQELSQLGSQLQGLSVS-GRGSCCGQLALINARMDG 397
R+ E+G+ +L + LDG L++++ + + + L GR Q AL A +G
Sbjct: 1061 RKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG 1120
Query: 398 LERA--LQAVTETQRGPGAPAGD-ELTRLSAAMLEGGVDGLLEGLETLNGT-EGGARGCC 453
RA L+++ E Q D E R++ E L E LE L G E
Sbjct: 1121 GARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTN 1180
Query: 454 LRLDMGG---WGVGGFGTMLEER-------VQSLEERLATLAGELSH--DSASPGRSA-- 499
+ ++ V LEE VQ L +R GEL+ + A G+ A
Sbjct: 1181 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1240
Query: 500 --RPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQVASHAAL 557
R ++ E++ L L SL+T+ L +++ Q R+ R A A
Sbjct: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRR--RRLELQLQEVQGRAGDGERARAEAAEK 1298
Query: 558 LQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANT 617
LQ+ + V G L E +++ L L+S L + + + + A LA
Sbjct: 1299 LQRAQAELENVSGALNEAESKTIR-----LSKELSSTEAQLHDAQELLQEETRAKLA--- 1350
Query: 618 SLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQD 677
L R R +EAE ++EQ+ + + + R++ + +L + + + A L ++
Sbjct: 1351 -LGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEE 1409
Query: 678 TAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQ 737
++ QR+A+ RL R R L +D L Q
Sbjct: 1410 ARRRAAREAEALTQRLAEKTETVDRLE--------------RGRRRLQQELDDATMDLEQ 1455
Query: 738 HTQDIARLRDDLLDCQAQLAEQ 759
Q ++ L LAE+
Sbjct: 1456 QRQLVSTLEKKQRKFDQLLAEE 1477
Score = 35.4 bits (80), Expect = 0.20
Identities = 114/546 (20%), Positives = 205/546 (37%), Gaps = 66/546 (12%)
Query: 250 EILSKVTEVSNTLQTKVQLLD-KVHGLALGHEAHLQRLREAPPSPLTSLALLEEYVDRRL 308
E+L + T L ++V+ ++ + GL E A T+ A L E+ RR
Sbjct: 1339 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW-RRRQ 1397
Query: 309 HRLWGSLLDGFEQKLQGVQSECDL--RVQEVRRQCEEGQAASRRLHQSLDGRELALRQEL 366
G+L G E + + + L R+ E + + RRL Q LD + L Q+
Sbjct: 1398 EEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQ- 1456
Query: 367 SQLGSQLQGLSVSGRGSCCGQLALI--------NARMDGLERALQAVTETQR-GPGAPAG 417
QL S L+ + A + A +G ER +A++ T+ A
Sbjct: 1457 RQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAR 1516
Query: 418 DELTRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSL 477
+EL R + A L ++ LL + + + C + + T LE+ + +
Sbjct: 1517 EELERQNRA-LRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAA 1575
Query: 478 EERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEV 537
E+ L + A + R L + A E+R + D AEV
Sbjct: 1576 EDAKLRLEVTVQ---ALKTQHERDLQGRDEAGEERRR---------QLAKQLRD---AEV 1620
Query: 538 KAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKS 597
+ + R + L A ++L G + E++ Q+A G + + L+ + + K
Sbjct: 1621 ERDEERKQRTLAVAAR-----KKLEGELEELKAQMASA-GQGKEEAVKQLR-KMQAQMKE 1673
Query: 598 LTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQV-SSQGSRLQA---------- 646
L + + + N ++R + +EAEV +QE++ +S +R QA
Sbjct: 1674 LWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE 1733
Query: 647 ---GHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRL 703
G+ + E QL+ + ++ L Q ++ L + + + QVE L
Sbjct: 1734 VANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLN---DRYRKLLLQVESLTTEL 1790
Query: 704 GLLAAGLDSLPTEPLRPREGLWSHVDQLNRTL--------AQHTQDIARLRDDLLDCQAQ 755
+ S + R+ L + +L L A+H IA L L + Q
Sbjct: 1791 ----SAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQ 1846
Query: 756 LAEQVR 761
L ++ R
Sbjct: 1847 LEQETR 1852
Score = 31.2 bits (69), Expect = 3.8
Identities = 77/364 (21%), Positives = 133/364 (36%), Gaps = 77/364 (21%)
Query: 472 ERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILD 531
++VQ L+++ A GEL A L + A E + ET + L+
Sbjct: 879 QKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELE 938
Query: 532 SLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLA--EGTGSSLQGE------ 583
+V+E++A E RQ+ + LQQ + E++ L EG LQ E
Sbjct: 939 LVVSELEARVGEEEECSRQMQTEKKRLQQ---HIQELEAHLEAEEGARQKLQLEKVTTEA 995
Query: 584 --------ITLLKVNLNSVSKSLTGLSDSVSQYS--------------------DAFLA- 614
+ LL+ + +SK L D ++++S +A +A
Sbjct: 996 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1055
Query: 615 ----------ANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAG 664
L++ +R+++ E +QEQ+ Q R + Q+ EL+ A
Sbjct: 1056 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1115
Query: 665 V-------AKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRR----------LGLLA 707
A++ L Q + Q + +RVA+ + +R G L
Sbjct: 1116 AEDEGGARAQLLKSLREAQAALAEAQEDLE--SERVARTKAEKQRRDLGEELEALRGELE 1173
Query: 708 AGLDSLPTEPLRPREGLWSHVDQLNRTLAQHT-------QDIARLRDDLLDCQAQLAEQV 760
LDS + R V +L +TL + T Q++ + L A+ EQ
Sbjct: 1174 DTLDSTNAQQ-ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQA 1232
Query: 761 RPGQ 764
R G+
Sbjct: 1233 RRGK 1236
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 53.5 bits (127), Expect = 7e-07
Identities = 116/518 (22%), Positives = 194/518 (37%), Gaps = 93/518 (17%)
Query: 241 RGPLTPPLD------EILSK----VTEVSNTLQTK-------VQLLDKVHGLALGH---- 279
RG L LD E+ SK VTE+ TL+ + VQ L + HG ALG
Sbjct: 1210 RGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQ 1269
Query: 280 ------------------EAHLQRLREAPPSPLTSLALLEEYVDRRLHRL-------WGS 314
EA + LR + L+SL + ++R RL G
Sbjct: 1270 LEQARRGKGAWEKTRLALEAEVSELR----AELSSLQTARQEGEQRRRRLELQLQEVQGR 1325
Query: 315 LLDGFE------QKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGRELALR--QEL 366
DG +KLQ Q+E ++ V E ++ + RL + L E L QEL
Sbjct: 1326 AGDGERARAEAAEKLQRAQAE----LENVSGALNEAESKTIRLSKELSSTEAQLHDAQEL 1381
Query: 367 SQ--------LGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVT---------ETQ 409
Q LGS+++ + G QL A + R LQ + +
Sbjct: 1382 LQEETRAKLALGSRVRAMEAEAAG-LREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1440
Query: 410 RGPGAPAGDELTRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTM 469
AG+E R +A E L E ET++ E G R LD +
Sbjct: 1441 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL----EQ 1496
Query: 470 LEERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAI 529
+ V +LE++ L+ + A+ R+ + E E+ +L +
Sbjct: 1497 QRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEA 1556
Query: 530 LDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKV 589
+ L + +A ++ EALL + +L E ++AE + L+ ++T L+
Sbjct: 1557 REELERQNRALRAELEALLSSKDDVGKSVHEL-----ERACRVAEQAANDLRAQVTELED 1611
Query: 590 NLNSVSKSLTGLSDSV----SQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQ 645
L + + L +V +Q+ + + +ER R++ +++ + + + +
Sbjct: 1612 ELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1671
Query: 646 AGHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQ 683
L GELE+LKA +A G +K+Q
Sbjct: 1672 LAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQ 1709
Score = 52.4 bits (124), Expect = 2e-06
Identities = 100/442 (22%), Positives = 169/442 (38%), Gaps = 46/442 (10%)
Query: 339 RQCEEGQAASRRLHQSLDGRELALRQELSQLGSQLQGLSVS-GRGSCCGQLALINARMDG 397
R+ E+G+ +L + LDG L++++ + + + L GR Q AL A +G
Sbjct: 1102 RKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG 1161
Query: 398 LERA--LQAVTETQRGPGAPAGD-ELTRLSAAMLEGGVDGLLEGLETLNGT-EGGARGCC 453
RA L+++ E Q D E R++ E L E LE L G E
Sbjct: 1162 GARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTN 1221
Query: 454 LRLDMGG---WGVGGFGTMLEER-------VQSLEERLATLAGELSH--DSASPGRSA-- 499
+ ++ V LEE VQ L +R GEL+ + A G+ A
Sbjct: 1222 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281
Query: 500 --RPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQVASHAAL 557
R ++ E++ L L SL+T+ L +++ Q R+ R A A
Sbjct: 1282 KTRLALEAEVSELRAELSSLQTARQEGEQRR--RRLELQLQEVQGRAGDGERARAEAAEK 1339
Query: 558 LQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANT 617
LQ+ + V G L E +++ L L+S L + + + + A LA
Sbjct: 1340 LQRAQAELENVSGALNEAESKTIR-----LSKELSSTEAQLHDAQELLQEETRAKLA--- 1391
Query: 618 SLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQD 677
L R R +EAE ++EQ+ + + + R++ + +L + + + A L ++
Sbjct: 1392 -LGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEE 1450
Query: 678 TAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQ 737
++ QR+A+ RL R R L +D L Q
Sbjct: 1451 ARRRAAREAEALTQRLAEKTETVDRLE--------------RGRRRLQQELDDATMDLEQ 1496
Query: 738 HTQDIARLRDDLLDCQAQLAEQ 759
Q ++ L LAE+
Sbjct: 1497 QRQLVSTLEKKQRKFDQLLAEE 1518
Score = 35.4 bits (80), Expect = 0.20
Identities = 114/546 (20%), Positives = 205/546 (37%), Gaps = 66/546 (12%)
Query: 250 EILSKVTEVSNTLQTKVQLLD-KVHGLALGHEAHLQRLREAPPSPLTSLALLEEYVDRRL 308
E+L + T L ++V+ ++ + GL E A T+ A L E+ RR
Sbjct: 1380 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW-RRRQ 1438
Query: 309 HRLWGSLLDGFEQKLQGVQSECDL--RVQEVRRQCEEGQAASRRLHQSLDGRELALRQEL 366
G+L G E + + + L R+ E + + RRL Q LD + L Q+
Sbjct: 1439 EEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQ- 1497
Query: 367 SQLGSQLQGLSVSGRGSCCGQLALI--------NARMDGLERALQAVTETQR-GPGAPAG 417
QL S L+ + A + A +G ER +A++ T+ A
Sbjct: 1498 RQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAR 1557
Query: 418 DELTRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSL 477
+EL R + A L ++ LL + + + C + + T LE+ + +
Sbjct: 1558 EELERQNRA-LRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAA 1616
Query: 478 EERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEV 537
E+ L + A + R L + A E+R + D AEV
Sbjct: 1617 EDAKLRLEVTVQ---ALKTQHERDLQGRDEAGEERRR---------QLAKQLRD---AEV 1661
Query: 538 KAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKS 597
+ + R + L A ++L G + E++ Q+A G + + L+ + + K
Sbjct: 1662 ERDEERKQRTLAVAAR-----KKLEGELEELKAQMASA-GQGKEEAVKQLR-KMQAQMKE 1714
Query: 598 LTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQV-SSQGSRLQA---------- 646
L + + + N ++R + +EAEV +QE++ +S +R QA
Sbjct: 1715 LWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE 1774
Query: 647 ---GHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRL 703
G+ + E QL+ + ++ L Q ++ L + + + QVE L
Sbjct: 1775 VANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLN---DRYRKLLLQVESLTTEL 1831
Query: 704 GLLAAGLDSLPTEPLRPREGLWSHVDQLNRTL--------AQHTQDIARLRDDLLDCQAQ 755
+ S + R+ L + +L L A+H IA L L + Q
Sbjct: 1832 ----SAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQ 1887
Query: 756 LAEQVR 761
L ++ R
Sbjct: 1888 LEQETR 1893
Score = 31.2 bits (69), Expect = 3.8
Identities = 77/364 (21%), Positives = 133/364 (36%), Gaps = 77/364 (21%)
Query: 472 ERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILD 531
++VQ L+++ A GEL A L + A E + ET + L+
Sbjct: 920 QKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELE 979
Query: 532 SLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLA--EGTGSSLQGE------ 583
+V+E++A E RQ+ + LQQ + E++ L EG LQ E
Sbjct: 980 LVVSELEARVGEEEECSRQMQTEKKRLQQ---HIQELEAHLEAEEGARQKLQLEKVTTEA 1036
Query: 584 --------ITLLKVNLNSVSKSLTGLSDSVSQYS--------------------DAFLA- 614
+ LL+ + +SK L D ++++S +A +A
Sbjct: 1037 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1096
Query: 615 ----------ANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAG 664
L++ +R+++ E +QEQ+ Q R + Q+ EL+ A
Sbjct: 1097 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1156
Query: 665 V-------AKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRR----------LGLLA 707
A++ L Q + Q + +RVA+ + +R G L
Sbjct: 1157 AEDEGGARAQLLKSLREAQAALAEAQEDLE--SERVARTKAEKQRRDLGEELEALRGELE 1214
Query: 708 AGLDSLPTEPLRPREGLWSHVDQLNRTLAQHT-------QDIARLRDDLLDCQAQLAEQV 760
LDS + R V +L +TL + T Q++ + L A+ EQ
Sbjct: 1215 DTLDSTNAQQ-ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQA 1273
Query: 761 RPGQ 764
R G+
Sbjct: 1274 RRGK 1277
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 52.4 bits (124), Expect = 2e-06
Identities = 76/394 (19%), Positives = 160/394 (40%), Gaps = 48/394 (12%)
Query: 320 EQKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGRELALRQELSQLGSQLQGLSVS 379
E+K++ ++ EC + +++ + A + L S + +++EL L S+ LS S
Sbjct: 950 EEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQ-TVKEELESLRSEKDQLSAS 1008
Query: 380 GRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAG-DELTR------LSAAMLEGGV 432
R G + N ++ +++ Q E +R ++LTR L +
Sbjct: 1009 MRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDN 1068
Query: 433 DGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHDS 492
+ LL +ETL +LE ++ ++ A + EL +
Sbjct: 1069 EDLLARIETLQSN---------------------AKLLEVQILEVQRAKAMVDKELEAEK 1107
Query: 493 ASPGRSARPLVQT--ELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQ 550
+ + T EL L+ +L + + L VK ++ + +
Sbjct: 1108 LQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELEL------VKKDAQQTTLMNME 1161
Query: 551 VASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSD 610
+A + L+++LN + ++ + L+ EI + K ++ + +T L SV QY +
Sbjct: 1162 IADYERLMKELNQKLTNKNNKIED-----LEQEIKIQKQKQETLQEEITSLQSSVQQYEE 1216
Query: 611 AFLAANTSLDERERKVEAEVQAIQEQVSSQGS---RLQAGHRQVLNLRGELEQLKAGVAK 667
L + ++++ QA + + Q S L+A +QV + +L ++ + K
Sbjct: 1217 KNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHK 1276
Query: 668 VASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACR 701
+ L + +A++ Q T+ + QRV ++ CR
Sbjct: 1277 IHEHL---KTSAEQHQRTLSAYQQRVTALQEECR 1307
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 52.4 bits (124), Expect = 2e-06
Identities = 68/301 (22%), Positives = 118/301 (39%), Gaps = 35/301 (11%)
Query: 471 EERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAIL 530
+E + +L L E++ + A + V+ +L EQ + +++ S
Sbjct: 280 QEDAAVAKSKLRELNKEMAAEKAKAA-AGEAKVKKQLVAREQEITAVQARMQASYREH-- 336
Query: 531 DSLVAEVKAWQSRSEALLRQVAS----HAALLQQLNGTVAEVQGQLAEGTGSSLQGEITL 586
V EV+ Q + L Q+ + A LQQ N + + Q S E+
Sbjct: 337 ---VKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNAELAK 393
Query: 587 LKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERK-VEAEVQAIQEQVSSQGSRLQ 645
L+ L+ VSK L S++V Q DE++RK +EA+ A ++QV +LQ
Sbjct: 394 LRQELSKVSKELVEKSEAVRQ------------DEQQRKALEAKAAAFEKQV----LQLQ 437
Query: 646 AGHRQ--------VLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVE 697
A HR+ + + EL ++ A + + + Q+ Q++ A+V
Sbjct: 438 ASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVR 497
Query: 698 GACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQHTQDIARLRDDLLDCQAQLA 757
C L L L E + E + S L A+ QD+ + + Q +L
Sbjct: 498 SKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLK 557
Query: 758 E 758
E
Sbjct: 558 E 558
Score = 39.7 bits (91), Expect = 0.011
Identities = 51/202 (25%), Positives = 85/202 (42%), Gaps = 31/202 (15%)
Query: 477 LEERLATLAGELSHDSAS--PGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLV 534
L + L+ ++ EL S + R ++ + A E++++ L+ S S + L +
Sbjct: 394 LRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRESEEA--LQKRL 451
Query: 535 AEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSV 594
EV S L +SHA+L E Q Q+AE L ++ + + S
Sbjct: 452 DEV------SRELCHTQSSHASLRADAE-KAQEQQQQMAE-----LHSKLQSSEAEVRSK 499
Query: 595 SKSLTGLSDSVSQYSDAFLAANTSLDERERKVEA-----------EVQAIQEQVSSQGSR 643
+ L+GL + + A N+ L ER R +EA +VQA Q + Q +R
Sbjct: 500 CEELSGLHGQLQEAR----AENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTR 555
Query: 644 LQAGHRQVLNLRGELEQLKAGV 665
L+ QV L E +L+ V
Sbjct: 556 LKELESQVSGLEKEAIELREAV 577
Score = 38.5 bits (88), Expect = 0.024
Identities = 99/443 (22%), Positives = 159/443 (35%), Gaps = 66/443 (14%)
Query: 316 LDGFEQKLQGVQSE-CDLRVQEVRRQCEEGQAASRRLHQSLDGRELALR---QELSQLGS 371
LD ++L QS LR + Q ++ Q A LH L E +R +ELS L
Sbjct: 451 LDEVSRELCHTQSSHASLRADAEKAQEQQQQMAE--LHSKLQSSEAEVRSKCEELSGLHG 508
Query: 372 QLQGLSVSGRGSCCGQLALINARMD-GLERALQAVTETQRGPGAPAGDELTRLSAAMLEG 430
QLQ ++ I A ++ G R Q V +Q A A + TRL LE
Sbjct: 509 QLQEARAEN-SQLTERIRSIEALLEAGQARDAQDVQASQ----AEADQQQTRLKE--LES 561
Query: 431 GVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSH 490
V GL + E + E + D L E+ E LAT A +
Sbjct: 562 QVSGLEK--EAIELREAVEQQKVKNND------------LREKNWKAMEALAT-AEQACK 606
Query: 491 DSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQ 550
+ A+ + +L ++E + + + P + + ++ + + LL+
Sbjct: 607 EKLHSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKH 666
Query: 551 VASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSD 610
+ A L + E AE T S+LQ E + L L L SV
Sbjct: 667 PPAPAEPSSDLASKLRE-----AEETQSTLQAECDQYRSILAETEGMLRDLQKSV----- 716
Query: 611 AFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQ--VLNLRGELEQLKAGVAKV 668
+E E+ A+V A +E++ Q SR+ H + V L+GELE
Sbjct: 717 ---------EEEEQVWRAKVGAAEEEL--QKSRVTVKHLEEIVEKLKGELES-------- 757
Query: 669 ASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHV 728
+ H ++ +A C+ AGL L E + S
Sbjct: 758 ------SDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEA 811
Query: 729 DQLNRTLAQHTQDIARLRDDLLD 751
+ + LA Q ++ ++ + D
Sbjct: 812 QKQSDELALVRQQLSEMKSHVED 834
>gi|110611220 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 52.4 bits (124), Expect = 2e-06
Identities = 68/301 (22%), Positives = 118/301 (39%), Gaps = 35/301 (11%)
Query: 471 EERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAIL 530
+E + +L L E++ + A + V+ +L EQ + +++ S
Sbjct: 280 QEDAAVAKSKLRELNKEMAAEKAKAA-AGEAKVKKQLVAREQEITAVQARMQASYREH-- 336
Query: 531 DSLVAEVKAWQSRSEALLRQVAS----HAALLQQLNGTVAEVQGQLAEGTGSSLQGEITL 586
V EV+ Q + L Q+ + A LQQ N + + Q S E+
Sbjct: 337 ---VKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNAELAK 393
Query: 587 LKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERK-VEAEVQAIQEQVSSQGSRLQ 645
L+ L+ VSK L S++V Q DE++RK +EA+ A ++QV +LQ
Sbjct: 394 LRQELSKVSKELVEKSEAVRQ------------DEQQRKALEAKAAAFEKQV----LQLQ 437
Query: 646 AGHRQ--------VLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVE 697
A HR+ + + EL ++ A + + + Q+ Q++ A+V
Sbjct: 438 ASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVR 497
Query: 698 GACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQHTQDIARLRDDLLDCQAQLA 757
C L L L E + E + S L A+ QD+ + + Q +L
Sbjct: 498 SKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLK 557
Query: 758 E 758
E
Sbjct: 558 E 558
Score = 39.7 bits (91), Expect = 0.011
Identities = 51/202 (25%), Positives = 85/202 (42%), Gaps = 31/202 (15%)
Query: 477 LEERLATLAGELSHDSAS--PGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLV 534
L + L+ ++ EL S + R ++ + A E++++ L+ S S + L +
Sbjct: 394 LRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRESEEA--LQKRL 451
Query: 535 AEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSV 594
EV S L +SHA+L E Q Q+AE L ++ + + S
Sbjct: 452 DEV------SRELCHTQSSHASLRADAE-KAQEQQQQMAE-----LHSKLQSSEAEVRSK 499
Query: 595 SKSLTGLSDSVSQYSDAFLAANTSLDERERKVEA-----------EVQAIQEQVSSQGSR 643
+ L+GL + + A N+ L ER R +EA +VQA Q + Q +R
Sbjct: 500 CEELSGLHGQLQEAR----AENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTR 555
Query: 644 LQAGHRQVLNLRGELEQLKAGV 665
L+ QV L E +L+ V
Sbjct: 556 LKELESQVSGLEKEAIELREAV 577
Score = 38.5 bits (88), Expect = 0.024
Identities = 99/443 (22%), Positives = 159/443 (35%), Gaps = 66/443 (14%)
Query: 316 LDGFEQKLQGVQSE-CDLRVQEVRRQCEEGQAASRRLHQSLDGRELALR---QELSQLGS 371
LD ++L QS LR + Q ++ Q A LH L E +R +ELS L
Sbjct: 451 LDEVSRELCHTQSSHASLRADAEKAQEQQQQMAE--LHSKLQSSEAEVRSKCEELSGLHG 508
Query: 372 QLQGLSVSGRGSCCGQLALINARMD-GLERALQAVTETQRGPGAPAGDELTRLSAAMLEG 430
QLQ ++ I A ++ G R Q V +Q A A + TRL LE
Sbjct: 509 QLQEARAEN-SQLTERIRSIEALLEAGQARDAQDVQASQ----AEADQQQTRLKE--LES 561
Query: 431 GVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSH 490
V GL + E + E + D L E+ E LAT A +
Sbjct: 562 QVSGLEK--EAIELREAVEQQKVKNND------------LREKNWKAMEALAT-AEQACK 606
Query: 491 DSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQ 550
+ A+ + +L ++E + + + P + + ++ + + LL+
Sbjct: 607 EKLHSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKH 666
Query: 551 VASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSD 610
+ A L + E AE T S+LQ E + L L L SV
Sbjct: 667 PPAPAEPSSDLASKLRE-----AEETQSTLQAECDQYRSILAETEGMLRDLQKSV----- 716
Query: 611 AFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQ--VLNLRGELEQLKAGVAKV 668
+E E+ A+V A +E++ Q SR+ H + V L+GELE
Sbjct: 717 ---------EEEEQVWRAKVGAAEEEL--QKSRVTVKHLEEIVEKLKGELES-------- 757
Query: 669 ASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHV 728
+ H ++ +A C+ AGL L E + S
Sbjct: 758 ------SDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEA 811
Query: 729 DQLNRTLAQHTQDIARLRDDLLD 751
+ + LA Q ++ ++ + D
Sbjct: 812 QKQSDELALVRQQLSEMKSHVED 834
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 51.6 bits (122), Expect = 3e-06
Identities = 100/500 (20%), Positives = 182/500 (36%), Gaps = 69/500 (13%)
Query: 280 EAHLQRLREAPPSPLTSLALLEEYVDRRLHRLWGSLLDGFEQKLQGVQSECDLRVQEVR- 338
E L+ +E+ LEE + ++ L L +++L G Q + ++ + R
Sbjct: 1105 EGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARA 1164
Query: 339 RQCEEGQAASRRLHQSLDGRELALRQELSQLGSQLQ---GLSVSGRGSCCGQLALINARM 395
+ EE A R ++ + +EL +L +L+ G S R C + A +
Sbjct: 1165 EELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLR 1224
Query: 396 DGLERA-------LQAVTETQRGPGAPAGDELTRLSAAM---------LEGGVDGLLEGL 439
LE A + A+ Q A G+++ L L VD L +
Sbjct: 1225 RELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANV 1284
Query: 440 ETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHDSASPGRSA 499
ETL + A C E+++ + ++ L +L+ S GR
Sbjct: 1285 ETLTRAKASAEKLC--------------RTYEDQLSEAKIKVEELQRQLADASTQRGR-- 1328
Query: 500 RPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQVASHAA--- 556
+QTE L + L E + + L + E Q E+ + +HA
Sbjct: 1329 ---LQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQAL 1385
Query: 557 -----LLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDA 611
LL++ + AE Q +L +SK+ ++ S+Y
Sbjct: 1386 RHDCDLLREQHEEEAEAQAELQR------------------LLSKANAEVAQWRSKYEAD 1427
Query: 612 FLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASG 671
+ L+E ++K+ +Q +E V + ++ + + L L+ E E + + + S
Sbjct: 1428 AIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSA 1487
Query: 672 LSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQL 731
+ +K +H ++R Q E R L L TE R R G ++ L
Sbjct: 1488 AAALD---KKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEAL 1544
Query: 732 NRTLAQHTQDIARLRDDLLD 751
TL + +++ DL D
Sbjct: 1545 -ETLKRENKNLQEEISDLTD 1563
Score = 36.2 bits (82), Expect = 0.12
Identities = 99/490 (20%), Positives = 184/490 (37%), Gaps = 53/490 (10%)
Query: 316 LDGFEQKLQGVQSECDLRVQEVRRQCEEGQA-------ASRRLHQSLDGRELALRQELSQ 368
L ++L+ + V +RR+ EG A + +R+ Q L+ + LR E+
Sbjct: 1220 LGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDD 1279
Query: 369 LGSQLQGLS---VSGRGSCC---GQLALINARMDGLERALQAVTETQRGPGAPAGDELTR 422
L + ++ L+ S C QL+ +++ L+R L A TQRG EL+R
Sbjct: 1280 LAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQL-ADASTQRGRLQTESGELSR 1338
Query: 423 LSA------AMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQS 476
L + L G + LE L L + +L E+ +
Sbjct: 1339 LLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEE 1398
Query: 477 LEERLATLAGELSHDSASPGR-----SARPLVQTELAVLEQRLVSL---ETSCTPSTTSA 528
E A L LS +A + A + +TE ++ ++L E +A
Sbjct: 1399 EAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANA 1458
Query: 529 ILDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLK 588
SL Q+ SE + ++ + L+ ++ L E + ++
Sbjct: 1459 KCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEE-----MQ 1513
Query: 589 VNLNSVSKSLTGLSDSVSQYS---DAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQ 645
L + + GL + + + L A +L + ++ E+ + +QVS G +Q
Sbjct: 1514 RELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQ 1573
Query: 646 AGHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQ-----KLQHTVGHFDQRVAQVEGAC 700
+ L GE +++A + + A G ++T +L D+++A+ + C
Sbjct: 1574 ELEKTKKALEGEKSEIQAALEE-AEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEEC 1632
Query: 701 --------RRLGLLAAGLDS---LPTEPLRPREGLWSHVDQLNRTLAQHTQDIARLRDDL 749
R + L A LD+ E LR ++ + ++ L L T+ +
Sbjct: 1633 ANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAAT 1692
Query: 750 LDCQAQLAEQ 759
QAQL E+
Sbjct: 1693 RLMQAQLKEE 1702
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 50.1 bits (118), Expect = 8e-06
Identities = 55/250 (22%), Positives = 99/250 (39%), Gaps = 33/250 (13%)
Query: 470 LEERVQSLEERLATLAGELS---------HDSASPGRSARPLVQTELAVLEQRLVSLET- 519
LE RV+ EER L E + SAR +Q E E +L LE
Sbjct: 920 LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEE 979
Query: 520 -------SCTPSTTSAILDSLVAE----VKAWQSRSEALLRQVASHAALLQQLNGTVA-- 566
+C + +L+ +AE + + +S++L + H A++ L +
Sbjct: 980 QIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRRE 1039
Query: 567 EVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERE--- 623
E Q Q E T L+G+ T L + + + L +++ + AA ++E
Sbjct: 1040 EKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK 1099
Query: 624 -------RKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQ 676
R++E+++ +QE + S+ + +Q +L ELE LK + + Q
Sbjct: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 677 DTAQKLQHTV 686
+ K + V
Sbjct: 1160 ELRSKREQEV 1169
Score = 45.1 bits (105), Expect = 3e-04
Identities = 91/450 (20%), Positives = 164/450 (36%), Gaps = 44/450 (9%)
Query: 256 TEVSNTLQTKVQLLDKVHGLALGHEAHLQRLREAPPSPLTSLALLEEYVDR------RLH 309
TE+ + + +K + VH L A Q++ E T L LE+ + RL
Sbjct: 1504 TEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMK----TQLEELEDELQATEDAKLRLE 1559
Query: 310 RLWGSLLDGFEQKLQGVQSECDLRVQEVRRQCEEGQAA---SRRLHQSLDGRELALRQEL 366
++ FE+ LQG + + + +++ RQ E +A R+ L +L
Sbjct: 1560 VNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDL 1619
Query: 367 SQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAA 426
L + + + R QL + A+M R L ++ A A + +L +
Sbjct: 1620 KDLEAHIDSAN-KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSM 1678
Query: 427 MLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVG---GFGTMLEERVQSLEERLAT 483
E +++ E L E R D + G G + E + LE R+A
Sbjct: 1679 EAE-----MIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQ 1733
Query: 484 LAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSR 543
L EL + + TEL + RL T L+ A+ ++
Sbjct: 1734 LEEELEEEQGN----------TEL--INDRLKKANLQIDQINTDLNLERSHAQKN--ENA 1779
Query: 544 SEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSD 603
+ L RQ LQ++ GTV + + ++L+ +I L+ L++ +K
Sbjct: 1780 RQQLERQNKELKVKLQEMEGTVKSKY----KASITALEAKIAQLEEQLDNETKERQAACK 1835
Query: 604 SVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKA 663
V + +D+ R E ++Q +RL+ RQ+ E ++ A
Sbjct: 1836 QVRRTEKKLKDVLLQVDDERRNAEQ----YKDQADKASTRLKQLKRQLEEAEEEAQRANA 1891
Query: 664 GVAKVASGLSRCQDTAQKLQHTVGHFDQRV 693
K+ L +TA + V ++
Sbjct: 1892 SRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 42.4 bits (98), Expect = 0.002
Identities = 36/170 (21%), Positives = 76/170 (44%), Gaps = 8/170 (4%)
Query: 588 KVNLNSVSKSL-TGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQA 646
K L ++K T + D +S D + + L++ +R +E +V+ ++ Q+ LQA
Sbjct: 1492 KAELERLNKQFRTEMEDLMSSKDDVGKSVH-ELEKSKRALEQQVEEMKTQLEELEDELQA 1550
Query: 647 GHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLL 706
L L L+ +KA + G R + + +K + V + A++E ++ +
Sbjct: 1551 TEDAKLRLEVNLQAMKAQFERDLQG--RDEQSEEKKKQLVRQVREMEAELEDERKQRSMA 1608
Query: 707 AAGLDSLPTEPLRPREGLWSHVDQLNRTLAQHTQDIARLRDDLLDCQAQL 756
A L + + L +H+D N+ + + + +L+ + DC +L
Sbjct: 1609 VAARKKLEMD----LKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMREL 1654
Score = 40.0 bits (92), Expect = 0.008
Identities = 105/532 (19%), Positives = 198/532 (37%), Gaps = 79/532 (14%)
Query: 249 DEILSKVTEVSNTLQTKVQLLDKVHGLALGHEAHLQRLREAPPSPLTSLALLEEYVDRRL 308
+E L KV E + ++ ++ + + + LQ +A T L E + RL
Sbjct: 851 EEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAE----TELCAEAEELRARL 906
Query: 309 HRLWGSLLDGFEQKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGRELALRQELSQ 368
+Q+L+ + + + RV+E +C+ QA +++ Q++ L ++L +
Sbjct: 907 --------TAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQ----ELEEQLEE 954
Query: 369 LGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAML 428
S Q L + + A++ LE Q + E Q A +L
Sbjct: 955 EESARQKLQL--------EKVTTEAKLKKLEEE-QIILEDQNCKLAK--------EKKLL 997
Query: 429 EGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEER---LATLA 485
E D + E L E ++ + + T LEER++ E++ L
Sbjct: 998 E---DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMI----TDLEERLRREEKQRQELEKTR 1050
Query: 486 GELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSE 545
+L DS L Q ++A L+ +L E L + +A V+ ++
Sbjct: 1051 RKLEGDSTDLSDQIAEL-QAQIAELKMQLAKKEEE---------LQAALARVEEEAAQKN 1100
Query: 546 ALLRQVASHAALLQQLNGTVAEVQGQL---------AEGTGSSLQGEITLLKVNLNSVSK 596
L+++ ++L ++E+Q L AE L E+ LK L
Sbjct: 1101 MALKKI-------RELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLD 1153
Query: 597 SLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRG 656
S + S+ +L+E + EA++Q ++++ S L Q ++
Sbjct: 1154 STAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKA 1213
Query: 657 ELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTE 716
LE+ K + L+ + + L G + + +VE + L + + + TE
Sbjct: 1214 NLEKAKQTLENERGELA---NEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270
Query: 717 PLRPREGLWSHVDQLNRTLAQH-------TQDIARLRDDLLDCQAQLAEQVR 761
L +D + L+Q T+D + L L D Q L E+ R
Sbjct: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENR 1322
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 50.1 bits (118), Expect = 8e-06
Identities = 149/669 (22%), Positives = 254/669 (37%), Gaps = 100/669 (14%)
Query: 148 QIPSGQLDPGPRPPSYSRAAPSPHGRKGPGLFGE-RLERLEGDVQRLAQTYGTLSGLVAS 206
+ P G+L P ++ P + GP +LE EG Q L +G +
Sbjct: 628 EAPQGELVP----EAWGLRQEGPEHKPGPSEPSSVQLEEQEGPNQGL----DLATGQAEA 679
Query: 207 HEDPNRMTGGPRAPA-------------VPVGFGVIPEGLVGPGDRARGPLTPPLDEILS 253
E R+ G R PA V V G IP + G + L + ++
Sbjct: 680 REHDQRLEGTVRDPAWQKPQQKSEGALEVQVWEGPIPGESLASGVAEQEALREEVAQLRR 739
Query: 254 KVTEVSNTLQTKVQLLDKVHGLALG------------HEAHLQ---------RLREAPPS 292
K + + L+ + + L+ + A EAH + RLREA +
Sbjct: 740 KAEALGDELEAQARKLEAQNTEAARLSKELAQARRAEAEAHREAEAQAWEQARLREAVEA 799
Query: 293 PLTSL--------ALLEEYV----DRRLHRLWGSLL----DGFEQKLQGVQSECDLRVQE 336
L AL+E +RR GS L + E+++Q ++SE ++E
Sbjct: 800 AGQELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAAEERMQVLESEGRQHLEE 859
Query: 337 VRRQCEEGQAASRRLHQSL-DGRELALRQELSQLGSQLQGLSVSGRGSCCGQLALINARM 395
R+ E +A L +++ G+EL R L L +L+ ++ R + + R
Sbjct: 860 AERERREKEALQAELEKAVVRGKELGAR--LEHLQRELEQAALE-RQEFLREKESQHQRY 916
Query: 396 DGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLR 455
GLE+ L+A + A EL + A LE + L +G L +
Sbjct: 917 QGLEQRLEAELQAAATSKEEALMEL-KTRALQLEEELFQLRQGPAGLGPKKRAEPQLVET 975
Query: 456 LDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLV 515
++ V ML +L+ +L L G+L + GR+ L+Q++ A +
Sbjct: 976 QNVRLIEVERSNAMLVAEKAALQGQLQHLEGQLG---SLQGRAQELLLQSQRAQEHSSRL 1032
Query: 516 SLETSCTPSTTSAI---LDSLVAEVKAW-QSRSEALLRQVA---SHAALLQQLNGTVAEV 568
E S + L+ L EV+A QS+ E +Q A H AL Q AE+
Sbjct: 1033 QAEKSVLEIQGQELHRKLEVLEEEVRAARQSQEETRGQQQALLRDHKALAQLQRRQEAEL 1092
Query: 569 QGQLAEGTGSSLQGEITLLKV---NLNSVSKSLTGLSDSVSQYSDAFLAANTSLDE---R 622
+G L L+ + L++ L + L SV A LA L + R
Sbjct: 1093 EGLLVRHR--DLKANMRALELAHRELQGRHEQLQAQRASVEAQEVALLAERERLMQDGHR 1150
Query: 623 ERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKL 682
+R +E E++ +Q + L R+ L+GE +L+ +A++ ++ + +Q+L
Sbjct: 1151 QRGLEEELRRLQSEHDRAQMLLAELSRERGELQGERGELRGRLARLELERAQLEMQSQQL 1210
Query: 683 QHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQHTQDI 742
+ + D ++ C L L S ++ NR L Q +
Sbjct: 1211 RESNQQLDLSACRLTTQCELLTQLR------------------SAQEEENRQLLAEVQAL 1252
Query: 743 ARLRDDLLD 751
+R +LL+
Sbjct: 1253 SRENRELLE 1261
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/449 (19%), Positives = 183/449 (40%), Gaps = 73/449 (16%)
Query: 322 KLQGVQSECDLRVQEVRRQCEEGQAASR---RLHQSLDGRELALRQELSQLGSQLQGLSV 378
K + +S+ ++E+ + EE + L++ + L LR++L + Q + +
Sbjct: 1132 KTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVA 1191
Query: 379 SGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGLLEG 438
+ R +A + ++D L+R Q + + + S LE +D L
Sbjct: 1192 ALRKKHADSVAELGEQIDNLQRVKQKLEKEK--------------SEFKLE--IDDLSSS 1235
Query: 439 LETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAG--ELSHDSASPG 496
+E+++ ++ LE+ ++LE++L+ G E S S
Sbjct: 1236 MESVSKSKAN---------------------LEKICRTLEDQLSEARGKNEEIQRSLSEL 1274
Query: 497 RSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQVASHAA 556
+ + +QTE L ++L E+ I+ L +A+ ++E L RQ+
Sbjct: 1275 TTQKSRLQTEAGELSRQLEEKES---------IVSQLSRSKQAFTQQTEELKRQLEEENK 1325
Query: 557 LLQQLNGTVAEVQGQ---LAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFL 613
L + + L E +G+ L + ++SK+ + ++ ++Y +
Sbjct: 1326 AKNALAHALQSSRHDCDLLREQYEEEQEGKAELQR----ALSKANSEVAQWRTKYETDAI 1381
Query: 614 AANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLS 673
L+E ++K+ +Q +EQV + ++ + + L+GE+E L V + A+ L+
Sbjct: 1382 QRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER-ANSLA 1440
Query: 674 RCQDTAQKLQHTVGHFDQRVAQVEGACRR-LGLLAAGLD---SLPTEPLRPREGLWSHVD 729
D Q+ +FD+ +A+ + C L A L SL TE + + +D
Sbjct: 1441 AALDKKQR------NFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALD 1494
Query: 730 QLNRTLAQHTQDIARLRDDLLDCQAQLAE 758
QL ++ L ++ D Q+AE
Sbjct: 1495 QLETVKREN----KNLEQEIADLTEQIAE 1519
Score = 40.4 bits (93), Expect = 0.006
Identities = 49/229 (21%), Positives = 93/229 (40%), Gaps = 14/229 (6%)
Query: 533 LVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLN 592
L E KA Q + L + + + LN T ++++ Q+ E SSL+ E L+V+L
Sbjct: 993 LTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQV-EDLESSLEQE-KKLRVDLE 1050
Query: 593 SVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVL 652
+ L G + LDER +K + E +Q +V + + +++
Sbjct: 1051 RNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIK 1110
Query: 653 NLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDS 712
L+ +E+L+ + + ++ + + +R+ + A G+ S
Sbjct: 1111 ELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEE-----------AGGVTS 1159
Query: 713 LPTEPLRPREGLWSHVDQ-LNRTLAQHTQDIARLRDDLLDCQAQLAEQV 760
E + RE + + + L QH +A LR D A+L EQ+
Sbjct: 1160 TQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQI 1208
Score = 35.8 bits (81), Expect = 0.15
Identities = 46/204 (22%), Positives = 84/204 (41%), Gaps = 30/204 (14%)
Query: 471 EERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAIL 530
E + + LEE+L TL E + +Q ++ + L+ E C
Sbjct: 868 EAKRKELEEKLVTLVQEKND------------LQLQVQAESENLLDAEERC--------- 906
Query: 531 DSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVN 590
D L+ + + EA +++V A +++N + + +L E S L+ +I L++
Sbjct: 907 DQLIKA----KFQLEAKIKEVTERAEDEEEINAELTAKKRKL-EDECSELKKDIDDLELT 961
Query: 591 LNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQ 650
L V K + V ++ + LDE K+ E +A+QE LQA +
Sbjct: 962 LAKVEKEKHATENKVKNLTEEL----SGLDETIAKLTREKKALQEAHQQALDDLQAEEDK 1017
Query: 651 VLNLRGELEQLKAGVAKVASGLSR 674
V +L +L+ V + S L +
Sbjct: 1018 VNSLNKTKSKLEQQVEDLESSLEQ 1041
Score = 30.8 bits (68), Expect = 4.9
Identities = 28/130 (21%), Positives = 55/130 (42%), Gaps = 12/130 (9%)
Query: 572 LAEGTGSSLQGEITLLKVNLNSVSKSLT----GLSDSVSQYSDAFLAANTSLDERERKVE 627
+ E + LQ E+ L+ L ++ L DS ++ NTSL ++K+E
Sbjct: 1674 IVERRANLLQAEVEELRATLEQTERARKLAEQELLDS-NERVQLLHTQNTSLIHTKKKLE 1732
Query: 628 AEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVG 687
++ +Q +V + R N + ++ A +A L + QDT+ L+
Sbjct: 1733 TDLMQLQSEV-------EDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK 1785
Query: 688 HFDQRVAQVE 697
+ +Q V ++
Sbjct: 1786 NLEQTVKDLQ 1795
>gi|126723390 ankyrin repeat domain 24 [Homo sapiens]
Length = 1146
Score = 48.1 bits (113), Expect = 3e-05
Identities = 89/398 (22%), Positives = 147/398 (36%), Gaps = 39/398 (9%)
Query: 318 GFEQKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSL------------DGRELALRQE 365
G E+ L+ + E ++ +CE +A + RL + + G LR
Sbjct: 731 GLEEALRQREREAAAELEAALGKCEAAEAEAGRLRERVREAEGSGASGGGGGDTTQLRAA 790
Query: 366 LSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSA 425
L Q L+ R S +L +A +D + E RG A EL +
Sbjct: 791 LEQAREDLR-----DRDSRLRELEAASACLDEARASRLLAEEEARGLRA----ELAQREE 841
Query: 426 AMLEGG--VDGLLEGLETLNGTEGGARGCCLRL----DMGGWGVGGFGTMLEERVQSLEE 479
A LE ++ L E L T T R L D V EE Q L E
Sbjct: 842 ARLEQSRELEVLREQLATARATGEQQRTAAAELGRARDAAEARVAELPAACEEARQGLAE 901
Query: 480 RLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKA 539
A E S P R L Q E L R SLE + A A ++A
Sbjct: 902 --LREASEALRQSVVPASEHRRL-QEEALELRGRAASLEQEVVATGKEA------ARLRA 952
Query: 540 WQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSV-SKSL 598
R ++ H ++ L VA+++GQL E + + +V ++ KS
Sbjct: 953 ELERERVCSVALSEHERIVGTLQANVAQLEGQLEELGRRHEKTSAEVFQVQREALFMKSE 1012
Query: 599 TGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGEL 658
+++ ++ L + ER R+ ++ Q ++ + ++ ++V NL+ L
Sbjct: 1013 RHAAEAQLATAEQQLRGLRTEAERARQAQSRAQEALDKAKEKDKKITELSKEVFNLKEAL 1072
Query: 659 EQLKAGVA--KVASGLSRCQDTAQKLQHTVGHFDQRVA 694
++ A +A +V + + +D Q+LQ VA
Sbjct: 1073 KEQPAALATPEVEALRDQVKDLQQQLQEAARDHSSVVA 1110
Score = 38.5 bits (88), Expect = 0.024
Identities = 70/316 (22%), Positives = 115/316 (36%), Gaps = 53/316 (16%)
Query: 391 INARMDGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGLLEGLETLNGTEGGAR 450
+ R+ GLE AL+ + +R A L + AA E G L E + G+ GA
Sbjct: 725 LETRIRGLEEALR---QREREAAAELEAALGKCEAAEAEAG--RLRERVREAEGS--GAS 777
Query: 451 GCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHDSA--SPGRSARPLVQTELA 508
G GG LE+ + L +R + L EL SA R++R L + E
Sbjct: 778 GG------GGGDTTQLRAALEQAREDLRDRDSRLR-ELEAASACLDEARASRLLAEEEAR 830
Query: 509 VLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEV 568
L L E E + QSR +LR+ + A + T A
Sbjct: 831 GLRAELAQRE-----------------EARLEQSRELEVLREQLATARATGEQQRTAAAE 873
Query: 569 QGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEA 628
G+ + + + L + L L ++ + + A+ R+++
Sbjct: 874 LGRARDAA----EARVAELPAACEEARQGLAELREASEALRQSVVPAS-----EHRRLQE 924
Query: 629 EVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGH 688
E ++ + +S + A ++ LR ELE+ + C + + VG
Sbjct: 925 EALELRGRAASLEQEVVATGKEAARLRAELERERV-----------CSVALSEHERIVGT 973
Query: 689 FDQRVAQVEGACRRLG 704
VAQ+EG LG
Sbjct: 974 LQANVAQLEGQLEELG 989
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 47.8 bits (112), Expect = 4e-05
Identities = 150/662 (22%), Positives = 248/662 (37%), Gaps = 107/662 (16%)
Query: 181 ERLERLEGDVQRLAQTYGTLSGLVASHEDPNRMTGGPRAPAVPVGFGVIPEGLVGPGDRA 240
E+ ++L D L+Q G L L + G VPV + E P +
Sbjct: 534 EQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALVPVNSS-LQEAWGKPEEEQ 592
Query: 241 RGPLTPPLD-----------EILSKVTEVSNTLQTKV---QLLD-KVHGLALGHEAHLQR 285
RG LD E+ E+ LQ V QLL+ K+ L ++A LQ+
Sbjct: 593 RGLQEAQLDDTKVQEGSQEEELRQANRELEKELQNVVGRNQLLEGKLQALQADYQA-LQQ 651
Query: 286 LREAPPSPLTSLALLEEYVDRRLHRLWGSLLDGFEQK-------------LQGVQSECDL 332
A L SL + + ++ SLL + K LQ + EC
Sbjct: 652 RESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKAQMAEKEAILQSKEGEC-- 709
Query: 333 RVQEVRRQCEEGQAASRRLHQSLDGRELALRQEL-------SQLGSQLQGLSVSGRG-SC 384
Q++R + E+ Q + H+ L E +Q+ ++ G Q G
Sbjct: 710 --QQLREEVEQCQQLAEARHRELRALESQCQQQTQLIEVLTAEKGQQGVGPPTDNEAREL 767
Query: 385 CGQLALINARMD---GLERALQA-VTETQRGPGAPAGDE------LTRLSAAMLEGG--V 432
QLAL A+++ G + LQA V + Q A D+ L+ A + E V
Sbjct: 768 AAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLV 827
Query: 433 DGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERV---QSLEERLATLAGELS 489
L E E LN C + G + EER Q EE L L ELS
Sbjct: 828 QQLKEQNEALNRAHVQELLQCSERE---------GALQEERADEAQQREEELRALQEELS 878
Query: 490 HDSASPGRSARPLVQTELAVLEQRL---------VSLETSCTPSTTSAILDSLVAEVKAW 540
S + Q E A L+++L + ++ + ++L V+
Sbjct: 879 QAKCSSEEA-----QLEHAELQEQLHRANTDTAELGIQVCALTVEKERVEEALACAVQEL 933
Query: 541 QSRSEALLRQ---VASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKS 597
Q EA R+ + A LQQ ++ E + + A+ SL G L+ L +
Sbjct: 934 QDAKEAASREREGLERQVAGLQQEKESLQE-KLKAAKAAAGSLPG----LQAQLAQAEQR 988
Query: 598 LTGLSDSVSQYSDA--FLAANTSLDERERKVEA--EVQAIQEQVSSQGSRLQAGHRQVLN 653
L ++ Q + F + +D + R A E ++++ Q+ QG +LQA V
Sbjct: 989 AQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGRQLQAAEEAVEK 1048
Query: 654 LRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVG-----HFDQRVAQVEGACRRLGLLAA 708
L+ + ++ ++ L+ CQ A + G ++ ++E A ++
Sbjct: 1049 LKATQADMGEKLSCTSNHLAECQ-AAMLRKDKEGAALREDLERTQKELEKATTKIQEYYN 1107
Query: 709 GLDSLPTEPLRPREGLWSHVDQLNRT---LAQHTQDIARLRD------DLLDCQAQLAEQ 759
L T R + + + +D LNRT L + ++ R +D D L+ Q +L+ +
Sbjct: 1108 KLCQEVTNRERNDQKMLADLDDLNRTKKYLEERLIELLRDKDALWQKSDALEFQQKLSAE 1167
Query: 760 VR 761
R
Sbjct: 1168 ER 1169
>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
Length = 508
Score = 45.8 bits (107), Expect = 1e-04
Identities = 54/227 (23%), Positives = 97/227 (42%), Gaps = 24/227 (10%)
Query: 467 GTMLEERVQSLEERLATLAG---ELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTP 523
G ML ER + L +L TL+ E R + A E R V LE
Sbjct: 68 GKMLLERNEELRRQLETLSAQHLEREERLQQENHELRRGLAARGAEWEARAVELEGD--- 124
Query: 524 STTSAILDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGE 583
+++L A++ +S + R+ A + L + N +++ Q ++ T LQ E
Sbjct: 125 ------VEALRAQLGEQRSEQQDSGRERARALSELSEQNLRLSQQLAQASQ-TEQELQRE 177
Query: 584 ITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSR 643
+ L+ + ++L G + ++ N L R + +EA+++ ++E+V R
Sbjct: 178 LDALRGQCQA--QALAGAE--LRTRLESLQGENQMLQSRRQDLEAQIRGLREEVEKGEGR 233
Query: 644 LQAGHRQVLNLRG-------ELEQLKAGVAKVASGLSRCQDTAQKLQ 683
LQ H ++L LR ELE+ ++ + S L R Q +L+
Sbjct: 234 LQTTHEELLLLRRERREHSLELERARSEAGEALSALRRLQRRVSELE 280
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 45.1 bits (105), Expect = 3e-04
Identities = 79/441 (17%), Positives = 173/441 (39%), Gaps = 57/441 (12%)
Query: 322 KLQGVQSECDLRVQEVRRQCEEGQAASR---RLHQSLDGRELALRQELSQLGSQLQGLSV 378
K + +S+ ++E+ + EE A+ +++ + +R++L + Q + +
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1196
Query: 379 SGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGLLEG 438
+ R +A + ++D L+R Q + + + + ++ +D L
Sbjct: 1197 TLRKKHADSVAELGEQIDNLQRVKQKLEKEK----------------SEMKMEIDDLASN 1240
Query: 439 LETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHDSASPGRS 498
+ET++ +G C L+ L E ++S EE L +L+ A GR
Sbjct: 1241 VETVSKAKGNLEKMCRTLE----------DQLSE-LKSKEEEQQRLINDLT---AQRGR- 1285
Query: 499 ARPLVQTELAVLEQRLVSLETSCTP-STTSAILDSLVAEVKAWQSRSEALLRQVASHAAL 557
+QTE ++L E + S + E+K Q E + +HA
Sbjct: 1286 ----LQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKR-QLEEEIKAKNALAHALQ 1340
Query: 558 LQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANT 617
+ + + Q + + + + LQ ++SK+ T ++ ++Y +
Sbjct: 1341 SSRHDCDLLREQYEEEQESKAELQ----------RALSKANTEVAQWRTKYETDAIQRTE 1390
Query: 618 SLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQD 677
L+E ++K+ +QA +E V + ++ + + L+ E+E L V + + +
Sbjct: 1391 ELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDK 1450
Query: 678 TAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQ 737
+ + + Q+ + L SL TE + + +DQL TL +
Sbjct: 1451 KQRNFDKILAEWKQKCEETHA---ELEASQKEARSLGTELFKIKNAYEESLDQL-ETLKR 1506
Query: 738 HTQDIARLRDDLLDCQAQLAE 758
++ L+ ++ D Q+AE
Sbjct: 1507 ENKN---LQQEISDLTEQIAE 1524
Score = 39.7 bits (91), Expect = 0.011
Identities = 47/232 (20%), Positives = 92/232 (39%), Gaps = 20/232 (8%)
Query: 533 LVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLN 592
L E KA Q + L + + + L +++ Q+ + GS Q + L+++L
Sbjct: 998 LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEK--KLRMDLE 1055
Query: 593 SVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQ---GSRLQAGHR 649
+ L G + LDE+ +K E E+ +Q ++ + G +LQ +
Sbjct: 1056 RAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQ---K 1112
Query: 650 QVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAG 709
++ L+ +E+L+ + + ++ + L + +R+ + A G
Sbjct: 1113 KIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE-----------AGG 1161
Query: 710 LDSLPTEPLRPREGLWSHVDQ-LNRTLAQHTQDIARLRDDLLDCQAQLAEQV 760
S E + RE + + + L QH A LR D A+L EQ+
Sbjct: 1162 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQI 1213
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 45.1 bits (105), Expect = 3e-04
Identities = 79/441 (17%), Positives = 173/441 (39%), Gaps = 57/441 (12%)
Query: 322 KLQGVQSECDLRVQEVRRQCEEGQAASR---RLHQSLDGRELALRQELSQLGSQLQGLSV 378
K + +S+ ++E+ + EE A+ +++ + +R++L + Q + +
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1196
Query: 379 SGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGLLEG 438
+ R +A + ++D L+R Q + + + + ++ +D L
Sbjct: 1197 TLRKKHADSVAELGEQIDNLQRVKQKLEKEK----------------SEMKMEIDDLASN 1240
Query: 439 LETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHDSASPGRS 498
+ET++ +G C L+ L E ++S EE L +L+ A GR
Sbjct: 1241 VETVSKAKGNLEKMCRTLE----------DQLSE-LKSKEEEQQRLINDLT---AQRGR- 1285
Query: 499 ARPLVQTELAVLEQRLVSLETSCTP-STTSAILDSLVAEVKAWQSRSEALLRQVASHAAL 557
+QTE ++L E + S + E+K Q E + +HA
Sbjct: 1286 ----LQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKR-QLEEEIKAKNALAHALQ 1340
Query: 558 LQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANT 617
+ + + Q + + + + LQ ++SK+ T ++ ++Y +
Sbjct: 1341 SSRHDCDLLREQYEEEQESKAELQ----------RALSKANTEVAQWRTKYETDAIQRTE 1390
Query: 618 SLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQD 677
L+E ++K+ +QA +E V + ++ + + L+ E+E L V + + +
Sbjct: 1391 ELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDK 1450
Query: 678 TAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQ 737
+ + + Q+ + L SL TE + + +DQL TL +
Sbjct: 1451 KQRNFDKILAEWKQKCEETHA---ELEASQKEARSLGTELFKIKNAYEESLDQL-ETLKR 1506
Query: 738 HTQDIARLRDDLLDCQAQLAE 758
++ L+ ++ D Q+AE
Sbjct: 1507 ENKN---LQQEISDLTEQIAE 1524
Score = 39.7 bits (91), Expect = 0.011
Identities = 47/232 (20%), Positives = 92/232 (39%), Gaps = 20/232 (8%)
Query: 533 LVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLN 592
L E KA Q + L + + + L +++ Q+ + GS Q + L+++L
Sbjct: 998 LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEK--KLRMDLE 1055
Query: 593 SVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQ---GSRLQAGHR 649
+ L G + LDE+ +K E E+ +Q ++ + G +LQ +
Sbjct: 1056 RAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQ---K 1112
Query: 650 QVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAG 709
++ L+ +E+L+ + + ++ + L + +R+ + A G
Sbjct: 1113 KIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE-----------AGG 1161
Query: 710 LDSLPTEPLRPREGLWSHVDQ-LNRTLAQHTQDIARLRDDLLDCQAQLAEQV 760
S E + RE + + + L QH A LR D A+L EQ+
Sbjct: 1162 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQI 1213
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 44.7 bits (104), Expect = 3e-04
Identities = 88/441 (19%), Positives = 178/441 (40%), Gaps = 46/441 (10%)
Query: 312 WGSLLDGFEQKLQGVQSECDLRVQE--VRRQCEEGQAASRRLHQSLDGRELALRQELSQL 369
W L + LQ + E +++ +E +++ E Q A L + L+ + L +E + L
Sbjct: 834 WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKE-LEQKHSQLTEEKNLL 892
Query: 370 GSQLQGLS--VSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAM 427
QLQ + + +LA ++ + ++A E + G E +++ M
Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 952
Query: 428 LEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGE 487
L+ L E LE E A L+L+ E +++ LE+ + +
Sbjct: 953 LD-----LEEQLE-----EEEAARQKLQLEK---------VTAEAKIKKLEDEILVM--- 990
Query: 488 LSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAIL-DSLVAEVKAWQSRSEA 546
D + R L++ ++ L L E T +S+++E++ + E
Sbjct: 991 --DDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK 1048
Query: 547 LLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVS 606
+++ L ++L G ++ Q+A+ LQ +I LK+ L +K L +++
Sbjct: 1049 SRQELEK---LKRKLEGDASDFHEQIAD-----LQAQIAELKMQL---AKKEEELQAALA 1097
Query: 607 QYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVA 666
+ D N +L ++ R++E + +QE + S+ + +Q +L ELE LK +
Sbjct: 1098 RLDDEIAQKNNAL-KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1156
Query: 667 KVASGLSRCQDTAQKLQHTV----GHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPRE 722
+ Q+ K + V D+ E + + A TE L +
Sbjct: 1157 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1216
Query: 723 GLWSHVDQLNRTLAQHTQDIA 743
+++D+ +TL + D+A
Sbjct: 1217 RAKANLDKNKQTLEKENADLA 1237
Score = 44.3 bits (103), Expect = 4e-04
Identities = 96/489 (19%), Positives = 192/489 (39%), Gaps = 61/489 (12%)
Query: 304 VDRRLHRLWGSLLDGFEQKLQGVQSE-CDLRVQEVRRQCEEGQAASRRLHQSLDGRELAL 362
+++ +L G D F +++ +Q++ +L++Q +++ EE QAA RL + + AL
Sbjct: 1053 LEKLKRKLEGDASD-FHEQIADLQAQIAELKMQLAKKE-EELQAALARLDDEIAQKNNAL 1110
Query: 363 RQ------ELSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAV---TETQRGPG 413
++ +S L L + R Q + ++ L+ L+ T TQ+
Sbjct: 1111 KKIRELEGHISDLQEDLDS-ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1169
Query: 414 APAGDELTRLSAAMLEG-----------------GVDGLLEGLETLNGTEGGARGCCLRL 456
A E+T L A+ E V+ L E LE + L
Sbjct: 1170 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTL 1229
Query: 457 DMGGWGVGGFGTMLEERVQSLEERLATLAGELSH--DSASPGRSARPLVQTELAVLEQRL 514
+ + G +L + Q +E + L ++ S G AR + ++ L+ +
Sbjct: 1230 EKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1289
Query: 515 VSLETSCTPSTTSAI-----LDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQ 569
S+ + AI + SL ++++ Q + RQ + + L+QL +Q
Sbjct: 1290 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1349
Query: 570 GQLAEGTGS--SLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVE 627
QL E + +L+ I+ L + L+ K L + +V +L+E +++ +
Sbjct: 1350 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVE-----------ALEEGKKRFQ 1398
Query: 628 AEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGV---AKVASGLSRCQDTAQKLQH 684
E++ + +Q + + + L+ EL+ L + ++ S L + Q +L
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 685 TVGHFDQRVA----QVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQHTQ 740
+ + A + E R A L E L +E L ++ N+ L +
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL----ERTNKMLKAEME 1514
Query: 741 DIARLRDDL 749
D+ +DD+
Sbjct: 1515 DLVSSKDDV 1523
Score = 43.5 bits (101), Expect = 7e-04
Identities = 53/284 (18%), Positives = 115/284 (40%), Gaps = 13/284 (4%)
Query: 424 SAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGG-FGTMLEERVQSLEERLA 482
S LE ++ + LE L LRL++ + G F L+ R + EE+
Sbjct: 1533 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1592
Query: 483 TLAGELSH--DSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAW 540
L +L R R L LE L LE + + + +++
Sbjct: 1593 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR--EEAIKQLRKL 1650
Query: 541 QSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTG 600
Q++ + R++ A ++ T E E SL+ ++ L+ +L + ++
Sbjct: 1651 QAQMKDFQRELEDARASRDEIFATAKE-----NEKKAKSLEADLMQLQEDLAAAERARKQ 1705
Query: 601 LS---DSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGE 657
+ +++ + L+ +L + +R++EA + ++E++ + ++A +V +
Sbjct: 1706 ADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ 1765
Query: 658 LEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACR 701
EQL +A S + + Q+L+ ++ ++EGA +
Sbjct: 1766 AEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK 1809
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 44.7 bits (104), Expect = 3e-04
Identities = 88/441 (19%), Positives = 178/441 (40%), Gaps = 46/441 (10%)
Query: 312 WGSLLDGFEQKLQGVQSECDLRVQE--VRRQCEEGQAASRRLHQSLDGRELALRQELSQL 369
W L + LQ + E +++ +E +++ E Q A L + L+ + L +E + L
Sbjct: 841 WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKE-LEQKHSQLTEEKNLL 899
Query: 370 GSQLQGLS--VSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAM 427
QLQ + + +LA ++ + ++A E + G E +++ M
Sbjct: 900 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 959
Query: 428 LEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGE 487
L+ L E LE E A L+L+ E +++ LE+ + +
Sbjct: 960 LD-----LEEQLE-----EEEAARQKLQLEK---------VTAEAKIKKLEDEILVM--- 997
Query: 488 LSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAIL-DSLVAEVKAWQSRSEA 546
D + R L++ ++ L L E T +S+++E++ + E
Sbjct: 998 --DDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK 1055
Query: 547 LLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVS 606
+++ L ++L G ++ Q+A+ LQ +I LK+ L +K L +++
Sbjct: 1056 SRQELEK---LKRKLEGDASDFHEQIAD-----LQAQIAELKMQL---AKKEEELQAALA 1104
Query: 607 QYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVA 666
+ D N +L ++ R++E + +QE + S+ + +Q +L ELE LK +
Sbjct: 1105 RLDDEIAQKNNAL-KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163
Query: 667 KVASGLSRCQDTAQKLQHTV----GHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPRE 722
+ Q+ K + V D+ E + + A TE L +
Sbjct: 1164 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1223
Query: 723 GLWSHVDQLNRTLAQHTQDIA 743
+++D+ +TL + D+A
Sbjct: 1224 RAKANLDKNKQTLEKENADLA 1244
Score = 44.3 bits (103), Expect = 4e-04
Identities = 96/489 (19%), Positives = 192/489 (39%), Gaps = 61/489 (12%)
Query: 304 VDRRLHRLWGSLLDGFEQKLQGVQSE-CDLRVQEVRRQCEEGQAASRRLHQSLDGRELAL 362
+++ +L G D F +++ +Q++ +L++Q +++ EE QAA RL + + AL
Sbjct: 1060 LEKLKRKLEGDASD-FHEQIADLQAQIAELKMQLAKKE-EELQAALARLDDEIAQKNNAL 1117
Query: 363 RQ------ELSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAV---TETQRGPG 413
++ +S L L + R Q + ++ L+ L+ T TQ+
Sbjct: 1118 KKIRELEGHISDLQEDLDS-ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1176
Query: 414 APAGDELTRLSAAMLEG-----------------GVDGLLEGLETLNGTEGGARGCCLRL 456
A E+T L A+ E V+ L E LE + L
Sbjct: 1177 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTL 1236
Query: 457 DMGGWGVGGFGTMLEERVQSLEERLATLAGELSH--DSASPGRSARPLVQTELAVLEQRL 514
+ + G +L + Q +E + L ++ S G AR + ++ L+ +
Sbjct: 1237 EKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1296
Query: 515 VSLETSCTPSTTSAI-----LDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQ 569
S+ + AI + SL ++++ Q + RQ + + L+QL +Q
Sbjct: 1297 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1356
Query: 570 GQLAEGTGS--SLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVE 627
QL E + +L+ I+ L + L+ K L + +V +L+E +++ +
Sbjct: 1357 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVE-----------ALEEGKKRFQ 1405
Query: 628 AEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGV---AKVASGLSRCQDTAQKLQH 684
E++ + +Q + + + L+ EL+ L + ++ S L + Q +L
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 685 TVGHFDQRVA----QVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQHTQ 740
+ + A + E R A L E L +E L ++ N+ L +
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL----ERTNKMLKAEME 1521
Query: 741 DIARLRDDL 749
D+ +DD+
Sbjct: 1522 DLVSSKDDV 1530
Score = 43.5 bits (101), Expect = 7e-04
Identities = 53/284 (18%), Positives = 115/284 (40%), Gaps = 13/284 (4%)
Query: 424 SAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGG-FGTMLEERVQSLEERLA 482
S LE ++ + LE L LRL++ + G F L+ R + EE+
Sbjct: 1540 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1599
Query: 483 TLAGELSH--DSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAW 540
L +L R R L LE L LE + + + +++
Sbjct: 1600 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR--EEAIKQLRKL 1657
Query: 541 QSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTG 600
Q++ + R++ A ++ T E E SL+ ++ L+ +L + ++
Sbjct: 1658 QAQMKDFQRELEDARASRDEIFATAKE-----NEKKAKSLEADLMQLQEDLAAAERARKQ 1712
Query: 601 LS---DSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGE 657
+ +++ + L+ +L + +R++EA + ++E++ + ++A +V +
Sbjct: 1713 ADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ 1772
Query: 658 LEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACR 701
EQL +A S + + Q+L+ ++ ++EGA +
Sbjct: 1773 AEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK 1816
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 44.7 bits (104), Expect = 3e-04
Identities = 88/441 (19%), Positives = 178/441 (40%), Gaps = 46/441 (10%)
Query: 312 WGSLLDGFEQKLQGVQSECDLRVQE--VRRQCEEGQAASRRLHQSLDGRELALRQELSQL 369
W L + LQ + E +++ +E +++ E Q A L + L+ + L +E + L
Sbjct: 841 WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKE-LEQKHSQLTEEKNLL 899
Query: 370 GSQLQGLS--VSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAM 427
QLQ + + +LA ++ + ++A E + G E +++ M
Sbjct: 900 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 959
Query: 428 LEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGE 487
L+ L E LE E A L+L+ E +++ LE+ + +
Sbjct: 960 LD-----LEEQLE-----EEEAARQKLQLEK---------VTAEAKIKKLEDEILVM--- 997
Query: 488 LSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAIL-DSLVAEVKAWQSRSEA 546
D + R L++ ++ L L E T +S+++E++ + E
Sbjct: 998 --DDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK 1055
Query: 547 LLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVS 606
+++ L ++L G ++ Q+A+ LQ +I LK+ L +K L +++
Sbjct: 1056 SRQELEK---LKRKLEGDASDFHEQIAD-----LQAQIAELKMQL---AKKEEELQAALA 1104
Query: 607 QYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVA 666
+ D N +L ++ R++E + +QE + S+ + +Q +L ELE LK +
Sbjct: 1105 RLDDEIAQKNNAL-KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163
Query: 667 KVASGLSRCQDTAQKLQHTV----GHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPRE 722
+ Q+ K + V D+ E + + A TE L +
Sbjct: 1164 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1223
Query: 723 GLWSHVDQLNRTLAQHTQDIA 743
+++D+ +TL + D+A
Sbjct: 1224 RAKANLDKNKQTLEKENADLA 1244
Score = 44.3 bits (103), Expect = 4e-04
Identities = 96/489 (19%), Positives = 192/489 (39%), Gaps = 61/489 (12%)
Query: 304 VDRRLHRLWGSLLDGFEQKLQGVQSE-CDLRVQEVRRQCEEGQAASRRLHQSLDGRELAL 362
+++ +L G D F +++ +Q++ +L++Q +++ EE QAA RL + + AL
Sbjct: 1060 LEKLKRKLEGDASD-FHEQIADLQAQIAELKMQLAKKE-EELQAALARLDDEIAQKNNAL 1117
Query: 363 RQ------ELSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAV---TETQRGPG 413
++ +S L L + R Q + ++ L+ L+ T TQ+
Sbjct: 1118 KKIRELEGHISDLQEDLDS-ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1176
Query: 414 APAGDELTRLSAAMLEG-----------------GVDGLLEGLETLNGTEGGARGCCLRL 456
A E+T L A+ E V+ L E LE + L
Sbjct: 1177 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTL 1236
Query: 457 DMGGWGVGGFGTMLEERVQSLEERLATLAGELSH--DSASPGRSARPLVQTELAVLEQRL 514
+ + G +L + Q +E + L ++ S G AR + ++ L+ +
Sbjct: 1237 EKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1296
Query: 515 VSLETSCTPSTTSAI-----LDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQ 569
S+ + AI + SL ++++ Q + RQ + + L+QL +Q
Sbjct: 1297 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1356
Query: 570 GQLAEGTGS--SLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVE 627
QL E + +L+ I+ L + L+ K L + +V +L+E +++ +
Sbjct: 1357 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVE-----------ALEEGKKRFQ 1405
Query: 628 AEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGV---AKVASGLSRCQDTAQKLQH 684
E++ + +Q + + + L+ EL+ L + ++ S L + Q +L
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 685 TVGHFDQRVA----QVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQHTQ 740
+ + A + E R A L E L +E L ++ N+ L +
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL----ERTNKMLKAEME 1521
Query: 741 DIARLRDDL 749
D+ +DD+
Sbjct: 1522 DLVSSKDDV 1530
Score = 43.5 bits (101), Expect = 7e-04
Identities = 53/284 (18%), Positives = 115/284 (40%), Gaps = 13/284 (4%)
Query: 424 SAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGG-FGTMLEERVQSLEERLA 482
S LE ++ + LE L LRL++ + G F L+ R + EE+
Sbjct: 1540 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1599
Query: 483 TLAGELSH--DSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAW 540
L +L R R L LE L LE + + + +++
Sbjct: 1600 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR--EEAIKQLRKL 1657
Query: 541 QSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTG 600
Q++ + R++ A ++ T E E SL+ ++ L+ +L + ++
Sbjct: 1658 QAQMKDFQRELEDARASRDEIFATAKE-----NEKKAKSLEADLMQLQEDLAAAERARKQ 1712
Query: 601 LS---DSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGE 657
+ +++ + L+ +L + +R++EA + ++E++ + ++A +V +
Sbjct: 1713 ADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ 1772
Query: 658 LEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACR 701
EQL +A S + + Q+L+ ++ ++EGA +
Sbjct: 1773 AEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK 1816
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 44.7 bits (104), Expect = 3e-04
Identities = 88/441 (19%), Positives = 178/441 (40%), Gaps = 46/441 (10%)
Query: 312 WGSLLDGFEQKLQGVQSECDLRVQE--VRRQCEEGQAASRRLHQSLDGRELALRQELSQL 369
W L + LQ + E +++ +E +++ E Q A L + L+ + L +E + L
Sbjct: 834 WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKE-LEQKHSQLTEEKNLL 892
Query: 370 GSQLQGLS--VSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAM 427
QLQ + + +LA ++ + ++A E + G E +++ M
Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 952
Query: 428 LEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGE 487
L+ L E LE E A L+L+ E +++ LE+ + +
Sbjct: 953 LD-----LEEQLE-----EEEAARQKLQLEK---------VTAEAKIKKLEDEILVM--- 990
Query: 488 LSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAIL-DSLVAEVKAWQSRSEA 546
D + R L++ ++ L L E T +S+++E++ + E
Sbjct: 991 --DDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK 1048
Query: 547 LLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVS 606
+++ L ++L G ++ Q+A+ LQ +I LK+ L +K L +++
Sbjct: 1049 SRQELEK---LKRKLEGDASDFHEQIAD-----LQAQIAELKMQL---AKKEEELQAALA 1097
Query: 607 QYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVA 666
+ D N +L ++ R++E + +QE + S+ + +Q +L ELE LK +
Sbjct: 1098 RLDDEIAQKNNAL-KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1156
Query: 667 KVASGLSRCQDTAQKLQHTV----GHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPRE 722
+ Q+ K + V D+ E + + A TE L +
Sbjct: 1157 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1216
Query: 723 GLWSHVDQLNRTLAQHTQDIA 743
+++D+ +TL + D+A
Sbjct: 1217 RAKANLDKNKQTLEKENADLA 1237
Score = 44.3 bits (103), Expect = 4e-04
Identities = 96/489 (19%), Positives = 192/489 (39%), Gaps = 61/489 (12%)
Query: 304 VDRRLHRLWGSLLDGFEQKLQGVQSE-CDLRVQEVRRQCEEGQAASRRLHQSLDGRELAL 362
+++ +L G D F +++ +Q++ +L++Q +++ EE QAA RL + + AL
Sbjct: 1053 LEKLKRKLEGDASD-FHEQIADLQAQIAELKMQLAKKE-EELQAALARLDDEIAQKNNAL 1110
Query: 363 RQ------ELSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAV---TETQRGPG 413
++ +S L L + R Q + ++ L+ L+ T TQ+
Sbjct: 1111 KKIRELEGHISDLQEDLDS-ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1169
Query: 414 APAGDELTRLSAAMLEG-----------------GVDGLLEGLETLNGTEGGARGCCLRL 456
A E+T L A+ E V+ L E LE + L
Sbjct: 1170 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTL 1229
Query: 457 DMGGWGVGGFGTMLEERVQSLEERLATLAGELSH--DSASPGRSARPLVQTELAVLEQRL 514
+ + G +L + Q +E + L ++ S G AR + ++ L+ +
Sbjct: 1230 EKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1289
Query: 515 VSLETSCTPSTTSAI-----LDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQ 569
S+ + AI + SL ++++ Q + RQ + + L+QL +Q
Sbjct: 1290 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1349
Query: 570 GQLAEGTGS--SLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVE 627
QL E + +L+ I+ L + L+ K L + +V +L+E +++ +
Sbjct: 1350 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVE-----------ALEEGKKRFQ 1398
Query: 628 AEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGV---AKVASGLSRCQDTAQKLQH 684
E++ + +Q + + + L+ EL+ L + ++ S L + Q +L
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 685 TVGHFDQRVA----QVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQHTQ 740
+ + A + E R A L E L +E L ++ N+ L +
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL----ERTNKMLKAEME 1514
Query: 741 DIARLRDDL 749
D+ +DD+
Sbjct: 1515 DLVSSKDDV 1523
Score = 43.5 bits (101), Expect = 7e-04
Identities = 53/284 (18%), Positives = 115/284 (40%), Gaps = 13/284 (4%)
Query: 424 SAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGG-FGTMLEERVQSLEERLA 482
S LE ++ + LE L LRL++ + G F L+ R + EE+
Sbjct: 1533 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1592
Query: 483 TLAGELSH--DSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAW 540
L +L R R L LE L LE + + + +++
Sbjct: 1593 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR--EEAIKQLRKL 1650
Query: 541 QSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTG 600
Q++ + R++ A ++ T E E SL+ ++ L+ +L + ++
Sbjct: 1651 QAQMKDFQRELEDARASRDEIFATAKE-----NEKKAKSLEADLMQLQEDLAAAERARKQ 1705
Query: 601 LS---DSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGE 657
+ +++ + L+ +L + +R++EA + ++E++ + ++A +V +
Sbjct: 1706 ADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ 1765
Query: 658 LEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACR 701
EQL +A S + + Q+L+ ++ ++EGA +
Sbjct: 1766 AEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK 1809
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 44.3 bits (103), Expect = 4e-04
Identities = 80/380 (21%), Positives = 148/380 (38%), Gaps = 56/380 (14%)
Query: 320 EQKLQGVQSECDLRVQEVRRQCEEGQAA----SRRLHQSLDGRELALRQELSQLGSQLQG 375
+QK++ + S+ +E++ + + + A SRRL ++L +E A EL QL +Q
Sbjct: 975 KQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAA-DAELGQLRAQ--- 1030
Query: 376 LSVSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGL 435
GS LAL + R+ LE LQAV+ ++ E+ L++ LE + +
Sbjct: 1031 -----GGSSDSSLAL-HERIQALEAELQAVSHSKTLLEKEL-QEVIALTSQELEESREKV 1083
Query: 436 LEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHD---- 491
LE + L + G ++++ LEE LA EL H+
Sbjct: 1084 LELEDELQESRG----------------------FRKKIKRLEESNKKLALELEHEKGKL 1121
Query: 492 -----SASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEA 546
S + R +++T LA E LV L A+L E + + +A
Sbjct: 1122 TGLGQSNAALREHNSILETALAKREADLVQLNLQ-----VQAVLQRKEEEDRQMKHLVQA 1176
Query: 547 LLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKS-----LTGL 601
L + + L VA + + + L +V +K L
Sbjct: 1177 LQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAE 1236
Query: 602 SDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQL 661
+D + + A++Q +Q+Q+ Q S+ G++++ NL+ E++Q
Sbjct: 1237 ADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQK 1296
Query: 662 KAGVAKVASGLSRCQDTAQK 681
+ + + L + +K
Sbjct: 1297 EREIQSLKQQLDLTEQQGRK 1316
Score = 43.9 bits (102), Expect = 6e-04
Identities = 119/606 (19%), Positives = 220/606 (36%), Gaps = 108/606 (17%)
Query: 181 ERLERLEGDVQRLAQTYGTLSGLVASHEDPNRMTGGPRAPAVPVGFGVIPEGLVGPGDRA 240
+ L+ L+ L G L G AS ED + + +I E +
Sbjct: 738 QSLDALQTHYDELQARLGELQGEAASREDTICLLQNEK---------IILEAALQAAKSG 788
Query: 241 RGPLTPPLDEILSKVTEVSNTLQTKVQLLDKVHGLALGHEAHLQRLREAPPSPLTSLA-- 298
+ L + E S TL+ + L + G HLQ+ A + +
Sbjct: 789 KEELDRGARRLEEGTEETSETLEKLREEL----AIKSGQVEHLQQETAALKKQMQKIKEQ 844
Query: 299 LLEEYVDRRLHRLWGSLLDGFEQKLQGVQSECDLRVQEVRRQCEE-------GQAASRRL 351
L++ V +R + D +L+ + D ++E+R++ + +A RL
Sbjct: 845 FLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRL 904
Query: 352 HQS----------LDGRELALRQELSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERA 401
H+ L+G + ++E ++ + LQ L Q+ + + L++
Sbjct: 905 HREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKE-----QMVAVTEANEALKKQ 959
Query: 402 LQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGW 461
++ + + R ++ RL + + + ++T + A G
Sbjct: 960 IEELQQEARKAITEQKQKMRRLGSDLTSAQKE-----MKTKHKAYENAVG---------- 1004
Query: 462 GVGGFGTMLEERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSC 521
+L R+Q EL A G S L L +R+ +LE
Sbjct: 1005 -------ILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLA------LHERIQALEAEL 1051
Query: 522 TP-STTSAILDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTG--- 577
S + +L+ + EV A S+ L++ V E++ +L E G
Sbjct: 1052 QAVSHSKTLLEKELQEVIALTSQE-------------LEESREKVLELEDELQESRGFRK 1098
Query: 578 --SSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQE 635
L+ L + L LTGL S + A N+ L+ K EA++ +
Sbjct: 1099 KIKRLEESNKKLALELEHEKGKLTGLGQS----NAALREHNSILETALAKREADLVQLNL 1154
Query: 636 QVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQ 695
QV + R + RQ+ +L V + + L + ++ L+ V A+
Sbjct: 1155 QVQAVLQRKEEEDRQMKHL----------VQALQASLEKEKEKVNSLKEQVA-----AAK 1199
Query: 696 VEGACRRLGLLAAGLD-SLPTEPLRPREGL----WSHVDQLNRTLAQHTQDIARLRDDLL 750
VE R AA L+ S + L+ +E L + D L +H+Q+IA+ + +L
Sbjct: 1200 VEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELA 1259
Query: 751 DCQAQL 756
+ +AQL
Sbjct: 1260 EARAQL 1265
Score = 40.0 bits (92), Expect = 0.008
Identities = 149/683 (21%), Positives = 246/683 (36%), Gaps = 140/683 (20%)
Query: 196 TYGTLSGLVASHEDPNRMTGGPRAPAVPVG-FGVIPEGLVGP-------GDRARGPLTPP 247
TYG LS V + + P M G PA +G F I + L G G +
Sbjct: 328 TYGILSKTVGTQDTPY-MVNGQEIPADTLGQFPSIKDVLQAAAAEHQDQGQEVNGEVRSR 386
Query: 248 LDEILSKVT----------EVSNTLQTKVQLLDKVHGL------ALGHEAHLQRLREAPP 291
D I S V+ E+ L+ K++L ++ L AL +A LQ A
Sbjct: 387 RDSICSSVSLESSAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALS 446
Query: 292 SPLTSLALLEEYVDRR-----------------LHRLWGSLLDGFEQKLQGV-QSECDLR 333
+ L + +R L R L + E K + S DL+
Sbjct: 447 TKLQAQVECSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQ 506
Query: 334 VQEVRRQCEEGQAAS-RRLHQSLDGRELALRQELSQLGSQLQGLSVSGRGSCCGQLALIN 392
V E + Q + +R S D LRQ+++ L SQLQ + + R + +L
Sbjct: 507 VAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLE-RTTLTSKLKASQ 565
Query: 393 ARMDGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVD-----GLLEGLETLNGTEG 447
A + +LQ+V + + A A + RL M V GLLE L+ N +
Sbjct: 566 AEIS----SLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLS 621
Query: 448 ----------------------GARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLA 485
G L + + TM+EE L+ RL
Sbjct: 622 QQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEE---DLQRRLEEFE 678
Query: 486 GE---LSHDSASPGRSARPLVQTELAVLE--QRLVSLETSCTPSTTSAILDSLVAEVKAW 540
GE L + S + L Q +L +L+ Q+L +L+ ++ L +A
Sbjct: 679 GERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLD-----LMKQLTLTQEAL 733
Query: 541 QSRSEALLRQVASHAALLQQLNGTVAEVQGQLA--EGTGSSLQGEITLLKVNLNS----- 593
QSR ++L + +H +L + E+QG+ A E T LQ E +L+ L +
Sbjct: 734 QSREQSL-DALQTH---YDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGK 789
Query: 594 --VSKSLTGLSDSVSQYSDAFLAANTSLDERERKVE----------AEVQAIQEQVSSQG 641
+ + L + + S+ L + +VE ++Q I+EQ Q
Sbjct: 790 EELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQK 849
Query: 642 SRLQAGHRQVLN--------------LRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVG 687
++A R + L EL++L+ + +V + +L V
Sbjct: 850 VMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVA 909
Query: 688 HFDQRVAQVEG----ACRRLGLLAAGLDSLPTEP------LRPREGLWSHVDQL----NR 733
Q +A +EG A + + L SL + E L +++L +
Sbjct: 910 QVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARK 969
Query: 734 TLAQHTQDIARLRDDLLDCQAQL 756
+ + Q + RL DL Q ++
Sbjct: 970 AITEQKQKMRRLGSDLTSAQKEM 992
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 43.9 bits (102), Expect = 6e-04
Identities = 73/443 (16%), Positives = 171/443 (38%), Gaps = 61/443 (13%)
Query: 322 KLQGVQSECDLRVQEVRRQCEEGQAASR---RLHQSLDGRELALRQELSQLGSQLQGLSV 378
K++ +S+ ++E+ + EE A+ +++ + +R++L + Q + +
Sbjct: 1135 KIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1194
Query: 379 SGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGLLEG 438
+ R +A + ++D L+R Q + + + + L+ +D +
Sbjct: 1195 TLRKKQADSVAELGEQIDNLQRVKQKLEKEK----------------SELKMEIDDMASN 1238
Query: 439 LETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSL---EERLATLAGELSHDSASP 495
+E L+ ++ C ++ + + + L + RL T GELSH
Sbjct: 1239 IEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEK 1298
Query: 496 GRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQVASHA 555
L +++ A+ +Q + E+K Q E + +HA
Sbjct: 1299 ESLISQLTKSKQALTQQ---------------------LEELKR-QMEEETKAKNAMAHA 1336
Query: 556 ALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAA 615
+ + + Q + + + LQ ++SK+ + ++ ++Y +
Sbjct: 1337 LQSSRHDCDLLREQYEEEQEAKAELQ----------RALSKANSEVAQWRTKYETDAIQR 1386
Query: 616 NTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRC 675
L+E ++K+ +Q +E + S+ + + L+GE+E L + + + +
Sbjct: 1387 TEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATL 1446
Query: 676 QDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTL 735
+ + + Q++ + + L SL TE + R VDQL TL
Sbjct: 1447 DKKQRNFDKVLAEWKQKLDESQA---ELEAAQKESRSLSTELFKMRNAYEEVVDQL-ETL 1502
Query: 736 AQHTQDIARLRDDLLDCQAQLAE 758
+ ++ L++++ D Q+AE
Sbjct: 1503 RRENKN---LQEEISDLTEQIAE 1522
Score = 35.8 bits (81), Expect = 0.15
Identities = 69/358 (19%), Positives = 130/358 (36%), Gaps = 85/358 (23%)
Query: 471 EERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAIL 530
E R + LEE++ +L E + +Q ++ + L+ E C S IL
Sbjct: 871 EARRKELEEKMVSLLQEKND------------LQLQVQSETENLMDAEERCEGLIKSKIL 918
Query: 531 DSLVAEVKAWQSRSE----------ALLRQVASHAALLQ------QLNGTVAEVQGQLAE 574
L A+VK R E A R + + L+ +L T E + E
Sbjct: 919 --LEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATE 976
Query: 575 GTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSD----------AFLAANTSLD---- 620
+L E+T L+ N++ ++K L ++ Q D + N L+
Sbjct: 977 NKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTD 1036
Query: 621 ------ERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSR 674
E+E+K+ A+++ + ++ L+ +++L + +Q++ + K LS+
Sbjct: 1037 DLEGSLEQEKKLRADLERAKRKLEGD---LKMSQESIMDLENDKQQIEEKLKKKEFELSQ 1093
Query: 675 CQ---DTAQ----KLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSH 727
Q D Q + Q + R+ ++E L A ++ ++ R E +
Sbjct: 1094 LQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISER 1153
Query: 728 VDQ-------------------------LNRTLAQHTQDIARLRDDLLDCQAQLAEQV 760
+++ L QH A LR D A+L EQ+
Sbjct: 1154 LEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQI 1211
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 43.9 bits (102), Expect = 6e-04
Identities = 108/492 (21%), Positives = 184/492 (37%), Gaps = 81/492 (16%)
Query: 327 QSECDLRVQEVRRQCEEGQAASRRLHQSLDGRELALRQELSQLGSQLQGLSVSGRGSCCG 386
Q+ L +E+ ++ ++ + RLH++L + L+ E SQ+ ++ LS G
Sbjct: 268 QAASPLEPKELEELRDKNESLTMRLHETLKQCQ-DLKTEKSQMDRKINQLSEEN-GDLSF 325
Query: 387 QLALINARMDGLERALQAVTE-----TQRGPGAPAGDELTRLSAAM------------LE 429
+L + + L+ AL +TE TQ A E LSAA+ L+
Sbjct: 326 KLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLE-KELSAALQDKKCLEEKNEILQ 384
Query: 430 GGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELS 489
G + L E L L +G L G +L+ +++L++ ATLA +
Sbjct: 385 GKLSQLEEHLSQLQDNPPQEKGEVL------------GDVLQ--LETLKQEAATLAANNT 430
Query: 490 HDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEV--------KAWQ 541
A Q E +L +R E S+ L S ++ + +A Q
Sbjct: 431 QLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQ 490
Query: 542 SRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGL 601
+ L QVAS + L LN T+ + +LA G + + L L ++ GL
Sbjct: 491 AHGARLTAQVASLTSELTTLNATIQQQDQELA-GLKQQAKEKQAQLAQTLQQQEQASQGL 549
Query: 602 SDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQL 661
V Q S + L E K EA Q +Q+++ +A R+ +LE L
Sbjct: 550 RHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEAL 609
Query: 662 -----------------------------------KAGVAKVASGLSRCQDTAQKLQHTV 686
KA +++ L C +TA++ QH
Sbjct: 610 EKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEA 669
Query: 687 GHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQHTQDIARLR 746
+VA++E R A + + E + +E L + + L T ++ R
Sbjct: 670 ---QAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAA 726
Query: 747 DDLLDCQAQLAE 758
D L + Q ++E
Sbjct: 727 DALEEQQRCISE 738
Score = 40.0 bits (92), Expect = 0.008
Identities = 66/295 (22%), Positives = 114/295 (38%), Gaps = 52/295 (17%)
Query: 497 RSARPLVQTELAVLEQRLVSL-----ET--SCTP-STTSAILDSLVAEVKAWQSRSEALL 548
++A PL EL L + SL ET C T + +D + ++ L
Sbjct: 268 QAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKL 327
Query: 549 RQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQY 608
R+ ASH LQQL + E+ + ++ T L+ + L K L+
Sbjct: 328 REFASH---LQQLQDALNELTEEHSKATQEWLEKQAQL--------EKELS--------- 367
Query: 609 SDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKV 668
A L L+E+ ++ ++ ++E +S +VL +LE LK A +
Sbjct: 368 --AALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATL 425
Query: 669 ASGLSRCQDTAQ-----------KLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEP 717
A+ ++ Q + KL GHF++ Q+ L + L E
Sbjct: 426 AANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEEL 485
Query: 718 LRPRE-----------GLWSHVDQLNRTLAQHTQDIARLRDDLLDCQAQLAEQVR 761
+ + L S + LN T+ Q Q++A L+ + QAQLA+ ++
Sbjct: 486 EQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ 540
Score = 38.5 bits (88), Expect = 0.024
Identities = 85/372 (22%), Positives = 140/372 (37%), Gaps = 51/372 (13%)
Query: 334 VQEVRRQCEEGQAASRRLHQSLDGRELALRQELSQLGSQLQGLSVSGRGSCCGQLALINA 393
+Q + R+ E+ RL +L + ++E Q ++ L+ RG LAL A
Sbjct: 967 LQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQE-RGRAQADLALEKA 1025
Query: 394 RMDGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGLLEGLETLNGTEGGARGCC 453
LE LQ QR A + L A+ E +G + L L G E
Sbjct: 1026 ARAELEMRLQNALNEQRVEFATLQEALAH---ALTEK--EGKDQELAKLRGLEAAQ---I 1077
Query: 454 LRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHDSASPGRSARPLVQT--ELAVLE 511
L+ L + V+ L+E+LA E + S + +A T +L L
Sbjct: 1078 KELEE-----------LRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALR 1126
Query: 512 QRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQ 571
+ LE C A DSL ++A ++ A + L+ L G + E +
Sbjct: 1127 AEVSKLEQQCQKQQEQA--DSLERSLEAERASR-------AERDSALETLQGQLEEKAQE 1177
Query: 572 LAEGTGS--SLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAE 629
L + S Q E+ + + SK+ V++ E ERK +
Sbjct: 1178 LGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVAR----------GRQEAERK-NSL 1226
Query: 630 VQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHF 689
+ +++E+VS +RQVL GE ++LK V + + ++ + LQ
Sbjct: 1227 ISSLEEEVSIL-------NRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASN 1279
Query: 690 DQRVAQVEGACR 701
R A+ A R
Sbjct: 1280 SARAAERSSALR 1291
Score = 37.4 bits (85), Expect = 0.053
Identities = 103/510 (20%), Positives = 184/510 (36%), Gaps = 105/510 (20%)
Query: 244 LTPPLDEILSKVTEVSNTLQTKVQLLDKVHGLALGHEAHLQRLREAPPSPLTSLALLEEY 303
LT + + S++T ++ T+Q + Q L A L++ + + L +E
Sbjct: 496 LTAQVASLTSELTTLNATIQQQDQEL-----------AGLKQQAKEKQAQLAQTLQQQEQ 544
Query: 304 VDRRLHRLWGSLLDGFEQKLQGVQSECDLR-------VQEVRRQCEEGQAASRRLHQSLD 356
+ L L +QK Q ++ + + Q++ EE +A+ R +L
Sbjct: 545 ASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALK 604
Query: 357 GRELALRQELSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERA-----LQAVTETQRG 411
E +++ ++L Q L V+ Q ++ A+ + E + LQA ET R
Sbjct: 605 QLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQ 664
Query: 412 PGAPAGDELTRLSAAM-------------------LEGGVDGLLEGLETLNGT-EGGARG 451
A ++ L + L+ + L E L+ G+ E R
Sbjct: 665 EQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRR 724
Query: 452 CCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHDSAS-PGRSAR-----PLVQT 505
L+ + + L+ +SL E+ EL + A G AR Q
Sbjct: 725 AADALEEQQRCI----SELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA 780
Query: 506 ELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTV 565
E VL + L E T + + LV EV AW+ R E ++ A + A+ Q+ T+
Sbjct: 781 ETEVLRRELA--EAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTL 838
Query: 566 ------------------------------------AEVQGQLA---------EGTGSSL 580
AE+ LA E L
Sbjct: 839 KEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKL 898
Query: 581 QGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSL-DERERKVEAEVQAIQEQVSS 639
+++ L+ + + SK + L V + + A+ L E R + + + ++EQ
Sbjct: 899 ADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGR 958
Query: 640 Q----GSRLQAGHRQVLNLRGELEQLKAGV 665
Q + LQA R+ + ELE+L+A +
Sbjct: 959 QFCSTQAALQAMEREAEQMGNELERLRAAL 988
Score = 35.0 bits (79), Expect = 0.26
Identities = 90/431 (20%), Positives = 166/431 (38%), Gaps = 55/431 (12%)
Query: 257 EVSNTLQTKVQLLDK---VHGLALGHEAHLQRLREAPPSPLTSLALLEEYVDRRLHRLWG 313
E+S LQ K L +K + G E HL +L++ PP + L + + +
Sbjct: 365 ELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEV--LGDVLQLETLKQEA 422
Query: 314 SLLDGFEQKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGRELALR--------QE 365
+ L +LQ + + E R +E + + R H + ++L+
Sbjct: 423 ATLAANNTQLQA-----RVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISN 477
Query: 366 LSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSA 425
LSQ +L+ S + Q+A + + + L +Q + G A ++ +L+
Sbjct: 478 LSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQ 537
Query: 426 AML--EGGVDGLLEGLETLNGT---------EGGARGCCLRLDMGGWGVGGFGTMLEERV 474
+ E GL +E L+ + E + R D T EER
Sbjct: 538 TLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQ----LATAAEERE 593
Query: 475 QSLEERLATLAGELSHDSASPGRSAR-PLVQTELAVLEQRLVSLETSCTPSTTSAILDSL 533
SL ER A L ++ ++A+ ++Q +L V + S +TS T + L
Sbjct: 594 ASLRERDAALK---QLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKA--EL 648
Query: 534 VAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNS 593
+V+ Q+ E ++ H A Q VAE++ QL + + E
Sbjct: 649 SRKVEELQACVETARQE--QHEAQAQ-----VAELELQLRSEQQKATEKE---------R 692
Query: 594 VSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLN 653
V++ L + + ++ SL+E +R+ ++ Q +S + ++ Q
Sbjct: 693 VAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKR 752
Query: 654 LRGELEQLKAG 664
R ELE+ +AG
Sbjct: 753 ERKELEEERAG 763
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,547,327
Number of Sequences: 37866
Number of extensions: 1644428
Number of successful extensions: 9959
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 358
Number of HSP's that attempted gapping in prelim test: 8741
Number of HSP's gapped (non-prelim): 1500
length of query: 766
length of database: 18,247,518
effective HSP length: 110
effective length of query: 656
effective length of database: 14,082,258
effective search space: 9237961248
effective search space used: 9237961248
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.