Guide to the Human Genome
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Search of human proteins with 4507541

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
         (245 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]        502   e-142
gi|21265104 tetraspanin 7 [Homo sapiens]                              301   3e-82
gi|87159824 CD151 antigen [Homo sapiens]                              139   2e-33
gi|87159822 CD151 antigen [Homo sapiens]                              139   2e-33
gi|21237751 CD151 antigen [Homo sapiens]                              139   2e-33
gi|21237748 CD151 antigen [Homo sapiens]                              139   2e-33
gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo ...   128   4e-30
gi|4502679 CD63 antigen isoform A [Homo sapiens]                      125   4e-29
gi|91199546 CD63 antigen isoform B [Homo sapiens]                     119   2e-27
gi|122937466 tetraspanin 11 [Homo sapiens]                            108   3e-24
gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]                   105   3e-23
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]       104   6e-23
gi|50511934 transmembrane 4 superfamily member 17 isoform b [Hom...   103   2e-22
gi|21264578 tetraspan 1 [Homo sapiens]                                102   2e-22
gi|4504813 CD82 antigen isoform 1 [Homo sapiens]                      102   4e-22
gi|30425534 tetraspanin 33 [Homo sapiens]                             101   5e-22
gi|54859505 transmembrane 4 superfamily member 17 isoform c [Hom...   101   5e-22
gi|54859560 transmembrane 4 superfamily member 17 isoform a [Hom...   101   7e-22
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]                  100   9e-22
gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]       100   1e-21
gi|5729941 tetraspanin 9 [Homo sapiens]                               100   2e-21
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]        100   2e-21
gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]                    95   5e-20
gi|38787991 transmembrane 4 superfamily member 8 isoform 2 [Homo...    93   2e-19
gi|4502693 CD9 antigen [Homo sapiens]                                  88   8e-18
gi|68800005 tetraspanin 4 isoform a [Homo sapiens]                     85   5e-17
gi|4507543 tetraspanin 4 isoform a [Homo sapiens]                      85   5e-17
gi|68800018 tetraspanin 4 isoform a [Homo sapiens]                     85   5e-17
gi|68800024 tetraspanin 4 isoform a [Homo sapiens]                     85   5e-17
gi|68800011 tetraspanin 4 isoform a [Homo sapiens]                     85   5e-17

>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
          Length = 245

 Score =  502 bits (1292), Expect = e-142
 Identities = 245/245 (100%), Positives = 245/245 (100%)

Query: 1   MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNV 60
           MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNV
Sbjct: 1   MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNV 60

Query: 61  PFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKN 120
           PFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKN
Sbjct: 61  PFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKN 120

Query: 121 SFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKL 180
           SFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKL
Sbjct: 121 SFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKL 180

Query: 181 EDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNN 240
           EDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNN
Sbjct: 181 EDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNN 240

Query: 241 QYEIV 245
           QYEIV
Sbjct: 241 QYEIV 245


>gi|21265104 tetraspanin 7 [Homo sapiens]
          Length = 249

 Score =  301 bits (772), Expect = 3e-82
 Identities = 146/248 (58%), Positives = 185/248 (74%), Gaps = 8/248 (3%)

Query: 5   SRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVL 64
           SRR++TKPVITC K++L+IY+F+FWITGVILLAVG+WGK++L  Y SL+ E +TN P+VL
Sbjct: 3   SRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVL 62

Query: 65  IATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKN 124
           I TGT I++ G FGCFATCR S WMLKLYAMFL+LVFL ELVA I GFVFRHEIK++F  
Sbjct: 63  IGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLR 122

Query: 125 NYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLE-DC 183
            Y  A++ YN   D RS AVD +Q +L CCGV +Y +W+ + Y+ E G P SCC  E DC
Sbjct: 123 TYTDAMQTYNG-NDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETDC 181

Query: 184 TPQR------DADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAI 237
            PQ        A KVN +GC+  V + +E+ MG++AG++FG+A  QLIG+ LA CLSR I
Sbjct: 182 NPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFI 241

Query: 238 TNNQYEIV 245
           T NQYE+V
Sbjct: 242 TANQYEMV 249


>gi|87159824 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  139 bits (350), Expect = 2e-33
 Identities = 74/239 (30%), Positives = 125/239 (52%), Gaps = 12/239 (5%)

Query: 16  CFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKA-TNVPFVLIATGTVIILL 74
           C K +L  Y   FW+ G+ ++AVGIW      +Y SLL         ++L+  GTV+++ 
Sbjct: 15  CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVT 74

Query: 75  GTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKAL-KQY 133
           G  GC AT +    +L+LY + L ++FL+E++A I+ + +  ++    K N +  + K+Y
Sbjct: 75  GVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRY 134

Query: 134 NSTG-DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYY--SEKG---FPKSCCK--LEDCTP 185
           +  G +  + AVD++Q   HCCG  + +DW D+ +    E G    P SCCK  +  C  
Sbjct: 135 HQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQ 194

Query: 186 QRDADKVN--NEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQY 242
           +  A  +     GC  K+ T I+  + V+  +  G+AC Q+ G+    CL R++    Y
Sbjct: 195 RDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY 253


>gi|87159822 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  139 bits (350), Expect = 2e-33
 Identities = 74/239 (30%), Positives = 125/239 (52%), Gaps = 12/239 (5%)

Query: 16  CFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKA-TNVPFVLIATGTVIILL 74
           C K +L  Y   FW+ G+ ++AVGIW      +Y SLL         ++L+  GTV+++ 
Sbjct: 15  CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVT 74

Query: 75  GTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKAL-KQY 133
           G  GC AT +    +L+LY + L ++FL+E++A I+ + +  ++    K N +  + K+Y
Sbjct: 75  GVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRY 134

Query: 134 NSTG-DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYY--SEKG---FPKSCCK--LEDCTP 185
           +  G +  + AVD++Q   HCCG  + +DW D+ +    E G    P SCCK  +  C  
Sbjct: 135 HQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQ 194

Query: 186 QRDADKVN--NEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQY 242
           +  A  +     GC  K+ T I+  + V+  +  G+AC Q+ G+    CL R++    Y
Sbjct: 195 RDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY 253


>gi|21237751 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  139 bits (350), Expect = 2e-33
 Identities = 74/239 (30%), Positives = 125/239 (52%), Gaps = 12/239 (5%)

Query: 16  CFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKA-TNVPFVLIATGTVIILL 74
           C K +L  Y   FW+ G+ ++AVGIW      +Y SLL         ++L+  GTV+++ 
Sbjct: 15  CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVT 74

Query: 75  GTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKAL-KQY 133
           G  GC AT +    +L+LY + L ++FL+E++A I+ + +  ++    K N +  + K+Y
Sbjct: 75  GVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRY 134

Query: 134 NSTG-DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYY--SEKG---FPKSCCK--LEDCTP 185
           +  G +  + AVD++Q   HCCG  + +DW D+ +    E G    P SCCK  +  C  
Sbjct: 135 HQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQ 194

Query: 186 QRDADKVN--NEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQY 242
           +  A  +     GC  K+ T I+  + V+  +  G+AC Q+ G+    CL R++    Y
Sbjct: 195 RDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY 253


>gi|21237748 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  139 bits (350), Expect = 2e-33
 Identities = 74/239 (30%), Positives = 125/239 (52%), Gaps = 12/239 (5%)

Query: 16  CFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKA-TNVPFVLIATGTVIILL 74
           C K +L  Y   FW+ G+ ++AVGIW      +Y SLL         ++L+  GTV+++ 
Sbjct: 15  CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVT 74

Query: 75  GTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKAL-KQY 133
           G  GC AT +    +L+LY + L ++FL+E++A I+ + +  ++    K N +  + K+Y
Sbjct: 75  GVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRY 134

Query: 134 NSTG-DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYY--SEKG---FPKSCCK--LEDCTP 185
           +  G +  + AVD++Q   HCCG  + +DW D+ +    E G    P SCCK  +  C  
Sbjct: 135 HQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQ 194

Query: 186 QRDADKVN--NEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQY 242
           +  A  +     GC  K+ T I+  + V+  +  G+AC Q+ G+    CL R++    Y
Sbjct: 195 RDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY 253


>gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo
           sapiens]
          Length = 253

 Score =  128 bits (322), Expect = 4e-30
 Identities = 77/241 (31%), Positives = 125/241 (51%), Gaps = 9/241 (3%)

Query: 14  ITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVP-FVLIATGTVII 72
           IT  K+VL+    IFW    IL  VG +  ++ ++Y     +  T +P  V+IA G ++ 
Sbjct: 6   ITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLF 65

Query: 73  LLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQ 132
           ++G  GC AT R S   L  + + L LVF+ E+V  ++G+V+R +++N    + +K  K 
Sbjct: 66  IIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKT 125

Query: 133 YNSTG-DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSE---KGFPKSCCK--LEDCTPQ 186
           YN T  D  S A+D +Q  LHCCG+ +Y DW +T+++ E   +  P SCC+    +C   
Sbjct: 126 YNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGS 185

Query: 187 -RDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLA-YCLSRAITNNQYEI 244
                 +  EGC   V+  ++  M  V   +   A  QL+G+  A   L R   +  YE+
Sbjct: 186 LAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYEL 245

Query: 245 V 245
           +
Sbjct: 246 L 246


>gi|4502679 CD63 antigen isoform A [Homo sapiens]
          Length = 238

 Score =  125 bits (313), Expect = 4e-29
 Identities = 68/232 (29%), Positives = 120/232 (51%), Gaps = 4/232 (1%)

Query: 16  CFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVIILLG 75
           C K +L +    F    V L+AVG+  ++ L           + +P V+IA G  + L+ 
Sbjct: 9   CVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVA 68

Query: 76  TFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNS 135
             GC   C+ +  ++  +A+FL+L+ LVE+ AAI G+VFR ++ + F NN+ + ++ Y  
Sbjct: 69  FVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENY-P 127

Query: 136 TGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCC--KLEDCTPQRDADKVN 193
             ++ +  +D++Q    CCG  +Y DW      S+   P SCC      C    +   ++
Sbjct: 128 KNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIH 187

Query: 194 NEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV 245
            EGC  K+   +   + VVA  + G+A  +++GI  A CL ++I +  YE++
Sbjct: 188 KEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRSG-YEVM 238


>gi|91199546 CD63 antigen isoform B [Homo sapiens]
          Length = 236

 Score =  119 bits (299), Expect = 2e-27
 Identities = 68/232 (29%), Positives = 119/232 (51%), Gaps = 6/232 (2%)

Query: 16  CFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVIILLG 75
           C K +L +    F    V L+AVG+  ++ L           + +P V+IA G  + L+ 
Sbjct: 9   CVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVA 68

Query: 76  TFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNS 135
             GC   C+ +  ++  +A+FL+L+ LVE+ AAI G+VFR ++ + F NN+ + ++ Y  
Sbjct: 69  FVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENY-P 127

Query: 136 TGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCC--KLEDCTPQRDADKVN 193
             ++ +  +D++Q    CCG  +Y DW      S+   P SCC      C    +   ++
Sbjct: 128 KNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIH 187

Query: 194 NEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV 245
            EGC  K+   +   + VVA  + G+A   ++GI  A CL ++I +  YE++
Sbjct: 188 KEGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCLVKSIRSG-YEVM 236


>gi|122937466 tetraspanin 11 [Homo sapiens]
          Length = 253

 Score =  108 bits (271), Expect = 3e-24
 Identities = 67/242 (27%), Positives = 110/242 (45%), Gaps = 12/242 (4%)

Query: 13  VITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLL-NEKATNVPFVLIATGTVI 71
           +I   K +L ++ F FW+ G  +LAVGIW  V    Y S+L +       ++LI  G ++
Sbjct: 12  LIIYLKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLV 71

Query: 72  ILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKAL- 130
           ++ G  G  A        L  Y   L ++FLVELVA ++  V+   + +  K +  + L 
Sbjct: 72  MVTGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLA 131

Query: 131 KQYNSTGDYR-SHAVDKIQNTLHCCGVTDYRDWTDTNYY-----SEKGFPKSCCKLEDCT 184
           + Y   G  + + +VD++Q    CCG     DW  + Y        +  P SCCK     
Sbjct: 132 ENYGQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVVVR 191

Query: 185 PQRDADKVN----NEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNN 240
             + A   N      GC  K+   +   + ++  +  GVAC Q+ G+ L  CL + +  +
Sbjct: 192 CGQRAHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHQRLQRH 251

Query: 241 QY 242
            Y
Sbjct: 252 FY 253


>gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]
          Length = 248

 Score =  105 bits (263), Expect = 3e-23
 Identities = 62/243 (25%), Positives = 112/243 (46%), Gaps = 20/243 (8%)

Query: 14  ITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLL--NEKATNVPFVLIATGTVI 71
           ++C K ++ ++ F  ++ G  LLA+GIW  V    +  ++  N       ++L+A G ++
Sbjct: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLL 65

Query: 72  ILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALK 131
            LLG  GC    R +  +L  + +F+ ++FL EL AAI+ F+FR  +   F         
Sbjct: 66  FLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHY 125

Query: 132 QYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYY-----SEKGFPKSCCK------- 179
           Q N+  D  S   + +  T  CCGV    D+   + +       +  P++CC+       
Sbjct: 126 QGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSRD 185

Query: 180 -----LEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLS 234
                 E+C   R    +N +GC+  ++   E+ + +   ++ GV   +L  +  A CL 
Sbjct: 186 GVLLSREECLLGRSL-FLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCLF 244

Query: 235 RAI 237
           R I
Sbjct: 245 RGI 247


>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
          Length = 268

 Score =  104 bits (260), Expect = 6e-23
 Identities = 67/245 (27%), Positives = 113/245 (46%), Gaps = 28/245 (11%)

Query: 13  VITCFKSVLLIYTFIFWITGVILLAVGIWG---KVSLENYFSLLNEKATNVPFVLIATGT 69
           V  C K  +  +  IFW  G+  L +G+W    K  L N  S+ +    +  ++ +  G 
Sbjct: 11  VSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGG 70

Query: 70  VIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKA 129
           V+ +LG  GC    R + ++LK +++FL ++F +EL A ++ FVF+  IK+         
Sbjct: 71  VMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFINNN 130

Query: 130 LKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDW--------TDTNYYSEK-GFPKSCCKL 180
           ++ Y    D + + +D  Q    CCG     DW        TD+N   E+ G P SCC  
Sbjct: 131 IRAYRDDIDLQ-NLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCCTK 189

Query: 181 E------------DCTPQRDADK---VNNEGCFIKVMTIIESEMGVVAGISFGVACFQLI 225
           +            D   + + D+   +  +GC  +    ++  + +VAGI  G+A  Q+ 
Sbjct: 190 DPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIF 249

Query: 226 GIFLA 230
           GI LA
Sbjct: 250 GICLA 254


>gi|50511934 transmembrane 4 superfamily member 17 isoform b [Homo
           sapiens]
          Length = 329

 Score =  103 bits (256), Expect = 2e-22
 Identities = 70/257 (27%), Positives = 117/257 (45%), Gaps = 28/257 (10%)

Query: 1   MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWG---KVSLENYFSLLNEKA 57
           M    +  Q   V  C K  L  +  +FW+ G + LA+G+W    K  L N  +L +   
Sbjct: 1   MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60

Query: 58  TNVPFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHE 117
            +  ++ +  G V+ +LG  GC    R + ++LK +++FL L+F +EL   I+ FVF+  
Sbjct: 61  LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120

Query: 118 IKNSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDW--------TDTNYYS 169
           I++         +K Y    D + + +D  Q    CCG     DW        TD N   
Sbjct: 121 IRDQLNLFINNNVKAYRDDIDLQ-NLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSR 179

Query: 170 EK-GFPKSCCKLE------------DCTPQRDADK---VNNEGCFIKVMTIIESEMGVVA 213
           E+ G P SCC  +            D   + + ++   ++ +GC  +    ++  + VVA
Sbjct: 180 ERCGVPFSCCVRDPAEDVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVA 239

Query: 214 GISFGVACFQLIGIFLA 230
           G+  G+A  Q+ GI LA
Sbjct: 240 GVFMGIALLQIFGICLA 256


>gi|21264578 tetraspan 1 [Homo sapiens]
          Length = 241

 Score =  102 bits (255), Expect = 2e-22
 Identities = 71/238 (29%), Positives = 115/238 (48%), Gaps = 23/238 (9%)

Query: 16  CF---KSVLLIYTFIFWITGVILLAVGIWGKV---SLENYFSLLNEKA---TNVPFVLIA 66
           CF   K++++++  + ++ G  LLAVGIW  +   S    F  L+  A    NV + LIA
Sbjct: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIA 62

Query: 67  TGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNY 126
            G V+  LG  GC+     S   L  +   L L+F+ E+ AA+V  V+    ++      
Sbjct: 63  AGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLV 122

Query: 127 EKALKQ-YNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSE-KGFPKSCCK----- 179
             A+K+ Y S  D+ +   +     L CCG T+Y D+ D+ Y+ E   FP  CC      
Sbjct: 123 VPAIKKDYGSQEDF-TQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVTN 181

Query: 180 --LEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLA---YC 232
              E CT Q+  D+   EGCF +++  I +    V G++ G+   +L  + ++   YC
Sbjct: 182 TANETCTKQKAHDQ-KVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYC 238


>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
          Length = 267

 Score =  102 bits (253), Expect = 4e-22
 Identities = 66/255 (25%), Positives = 115/255 (45%), Gaps = 27/255 (10%)

Query: 18  KSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNV---PFVLIATGTVIILL 74
           K  L ++  IF+I G ++L  G+W      ++ S+L   ++++    +V I  G V +L+
Sbjct: 10  KYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTMLM 69

Query: 75  GTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYN 134
           G  GC         +L LY  FL L+ + ++ A  + +    ++K        + ++ YN
Sbjct: 70  GFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYN 129

Query: 135 STG-DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYS---EKGFPKSC-CKLED------- 182
           S+  D    A D +Q  + CCG   + +WTD        E  +P SC  K E+       
Sbjct: 130 SSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNSLSVR 189

Query: 183 ---CTPQRDADKVNN---------EGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLA 230
              C    +  +  N         EGC  KV   ++  +G++ G+  GVA  +L+G+ L+
Sbjct: 190 KGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLS 249

Query: 231 YCLSRAITNNQYEIV 245
            CL R + +  Y  V
Sbjct: 250 ICLCRHVHSEDYSKV 264


>gi|30425534 tetraspanin 33 [Homo sapiens]
          Length = 283

 Score =  101 bits (252), Expect = 5e-22
 Identities = 64/244 (26%), Positives = 116/244 (47%), Gaps = 26/244 (10%)

Query: 18  KSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVIILLGTF 77
           K +L  +  +FW+  ++++AVG++ ++ +++  + L   A +   +LI  G ++ LL   
Sbjct: 23  KYLLFFFNMLFWVISMVMVAVGVYARL-MKHAEAALACLAVDPAILLIVVGVLMFLLTFC 81

Query: 78  GCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTG 137
           GC  + R +  +L+ +++ LT VFL++L A I+GFVF  + +         A+  Y    
Sbjct: 82  GCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDDL 141

Query: 138 DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYY--SEKGFPKSCCKL--EDCTPQRDADKVN 193
           D + + +D  Q    CCG   Y+DW+   Y+  SE    +  C +    C P  D   +N
Sbjct: 142 DLQ-NLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVIN 200

Query: 194 --------------------NEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCL 233
                                 GC  K++  I S + ++ G++ G+A  QL+GI L+  L
Sbjct: 201 TMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQIL 260

Query: 234 SRAI 237
              I
Sbjct: 261 VNQI 264


>gi|54859505 transmembrane 4 superfamily member 17 isoform c [Homo
           sapiens]
          Length = 266

 Score =  101 bits (252), Expect = 5e-22
 Identities = 72/265 (27%), Positives = 116/265 (43%), Gaps = 31/265 (11%)

Query: 1   MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWG---KVSLENYFSLLNEKA 57
           M    +  Q   V  C K  L  +  +FW+ G + LA+G+W    K  L N  +L +   
Sbjct: 1   MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60

Query: 58  TNVPFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHE 117
            +  ++ +  G V+ +LG  GC    R + ++LK +++FL L+F +EL   I+ FVF+  
Sbjct: 61  LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120

Query: 118 IKNSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDW--------TDTNYYS 169
           I++         +K Y    D + + +D  Q    CCG     DW        TD N   
Sbjct: 121 IRDQLNLFINNNVKAYRDDIDLQ-NLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSR 179

Query: 170 EK-GFPKSCC---KLEDCTPQR---------------DADKVNNEGCFIKVMTIIESEMG 210
           E+ G P SCC     ED    +                   ++ +GC  +    ++  + 
Sbjct: 180 ERCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLI 239

Query: 211 VVAGISFGVACFQLIGIFLAYCLSR 235
           VVAG+  G+A  Q+ GI LA  L +
Sbjct: 240 VVAGVFMGIALLQIFGICLAQNLEQ 264


>gi|54859560 transmembrane 4 superfamily member 17 isoform a [Homo
           sapiens]
          Length = 332

 Score =  101 bits (251), Expect = 7e-22
 Identities = 71/260 (27%), Positives = 114/260 (43%), Gaps = 31/260 (11%)

Query: 1   MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWG---KVSLENYFSLLNEKA 57
           M    +  Q   V  C K  L  +  +FW+ G + LA+G+W    K  L N  +L +   
Sbjct: 1   MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60

Query: 58  TNVPFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHE 117
            +  ++ +  G V+ +LG  GC    R + ++LK +++FL L+F +EL   I+ FVF+  
Sbjct: 61  LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120

Query: 118 IKNSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDW--------TDTNYYS 169
           I++         +K Y    D + + +D  Q    CCG     DW        TD N   
Sbjct: 121 IRDQLNLFINNNVKAYRDDIDLQ-NLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSR 179

Query: 170 EK-GFPKSCC---KLEDCTPQR---------------DADKVNNEGCFIKVMTIIESEMG 210
           E+ G P SCC     ED    +                   ++ +GC  +    ++  + 
Sbjct: 180 ERCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLI 239

Query: 211 VVAGISFGVACFQLIGIFLA 230
           VVAG+  G+A  Q+ GI LA
Sbjct: 240 VVAGVFMGIALLQIFGICLA 259


>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
          Length = 270

 Score =  100 bits (250), Expect = 9e-22
 Identities = 64/248 (25%), Positives = 114/248 (45%), Gaps = 29/248 (11%)

Query: 14  ITC-FKSVLLIYTFIFWITGVILLAVGIWG---KVSLENYFSLLNEKATNVPFVLIATGT 69
           ++C +K +L  Y  IFW+ GV+ L VG+W    K  L +   +      +   +++  G 
Sbjct: 11  VSCWYKYLLFSYNIIFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGV 70

Query: 70  VIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKA 129
           V+  LG  GC    R +  +L  +   + L+F +EL  A++ F+F+  +++ F+  +E  
Sbjct: 71  VMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESN 130

Query: 130 LKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDW--------TDTNYYSEK-GFPKSCC-- 178
           +K Y    D + + +D +Q    CCG     DW        +  +Y  EK G P SCC  
Sbjct: 131 IKSYRDDIDLQ-NLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVP 189

Query: 179 ----KLEDCTPQRDA---------DKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLI 225
               K+ +     D          + +  +GC   + + +   + +VAG+   ++  Q+ 
Sbjct: 190 DPAQKVVNTQCGYDVRIQLKSKWDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIF 249

Query: 226 GIFLAYCL 233
           GIFLA  L
Sbjct: 250 GIFLARTL 257


>gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]
          Length = 294

 Score =  100 bits (249), Expect = 1e-21
 Identities = 62/234 (26%), Positives = 110/234 (47%), Gaps = 25/234 (10%)

Query: 18  KSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVP-FVLIATGTVIILLGT 76
           K  L+IY+ +FW+ G ++L+VGI+ +V  + Y +L  E A   P  +LI  G V+ ++  
Sbjct: 21  KFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTL--ESAFLAPAIILILLGVVMFMVSF 78

Query: 77  FGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNST 136
            G  A+ R + ++L+ +   L +  ++EL+  +V   FR++  +   +N  + ++ Y   
Sbjct: 79  IGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYDD 138

Query: 137 GDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYS-------EKGFPKSCC----------- 178
            D++ + +D +Q    CCG  DYRDW+   Y+          G P +CC           
Sbjct: 139 LDFK-NIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTM 197

Query: 179 ---KLEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFL 229
              K  D       D +   GC   V+        ++AGI  G+   Q +G+ L
Sbjct: 198 CGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLL 251


>gi|5729941 tetraspanin 9 [Homo sapiens]
          Length = 239

 Score =  100 bits (248), Expect = 2e-21
 Identities = 62/235 (26%), Positives = 114/235 (48%), Gaps = 7/235 (2%)

Query: 14  ITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNE-KATNVPFVLIATGTVII 72
           + C K ++ ++  IFW+ G  LL VGIW  VS  N+ +      + +   ++IA GT+++
Sbjct: 6   LCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVM 65

Query: 73  LLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQ 132
           + G  GC    + +  +L  + + L ++ L EL+  I+ FV+  ++  + K + ++ L  
Sbjct: 66  VTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLL 125

Query: 133 YNSTGDY-RSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDA-D 190
           Y++  +    +A + IQ  + CCGVTDY DW       E   P  CC        R+A  
Sbjct: 126 YHTENNVGLKNAWNIIQAEMRCCGVTDYTDWYPV--LGENTVPDRCCMENSQGCGRNATT 183

Query: 191 KVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAI--TNNQYE 243
            +   GC+ KV    +    V+  +   +   Q++G+  +  L + I  T  +Y+
Sbjct: 184 PLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTLFQHIHRTGKKYD 238


>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
          Length = 237

 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 64/237 (27%), Positives = 113/237 (47%), Gaps = 14/237 (5%)

Query: 13  VITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFV----LIATG 68
           V  C K  +  + F+FW+ G+++LA+ IW +VS ++     +E   +  +V    LIA G
Sbjct: 4   VSACIKYSMFTFNFLFWLCGILILALAIWVRVSNDSQAIFGSEDVGSSSYVAVDILIAVG 63

Query: 69  TVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEK 128
            +I++LG  GC    + S  ML L+ + L L+ L+++   I+G VF+ +          +
Sbjct: 64  AIIMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLYE 123

Query: 129 ALKQYNSTGDYR---SHAVDKIQNTLHCCG-VTDYRDWTDTNYYSEKGFPKSCCKLEDCT 184
             K  ++TG+       A+   Q    CCG V    DW +   +    +P+ C  L+   
Sbjct: 124 NTKLLSATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNNFQH----YPELCACLDKQR 179

Query: 185 P--QRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITN 239
           P    +  +V  E C   +   +   + +V GISFG+A  +++G+  +  L   I N
Sbjct: 180 PCQSYNGKQVYKETCISFIKDFLAKNLIIVIGISFGLAVIEILGLVFSMVLYCQIGN 236


>gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]
          Length = 267

 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 56/229 (24%), Positives = 105/229 (45%), Gaps = 20/229 (8%)

Query: 14  ITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLL--NEKATNVPFVLIATGTVI 71
           ++C K ++ ++ F  ++ G  LLA+GIW  V    +  ++  N       ++L+A G ++
Sbjct: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLL 65

Query: 72  ILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALK 131
            LLG  GC    R +  +L  + +F+ ++FL EL AAI+ F+FR  +   F         
Sbjct: 66  FLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHY 125

Query: 132 QYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYY-----SEKGFPKSCCK------- 179
           Q N+  D  S   + +  T  CCGV    D+   + +       +  P++CC+       
Sbjct: 126 QGNNDTDVFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSRD 185

Query: 180 -----LEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQ 223
                 E+C   R    +N +GC+  ++   E+ + +   ++ GV   +
Sbjct: 186 GVLLSREECLLGRSL-FLNKQGCYTVILNTFETYVYLAGALAIGVLAIE 233


>gi|38787991 transmembrane 4 superfamily member 8 isoform 2 [Homo
           sapiens]
          Length = 228

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 68/241 (28%), Positives = 107/241 (44%), Gaps = 34/241 (14%)

Query: 14  ITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVP-FVLIATGTVII 72
           IT  K+VL+    IFW    IL  VG +  ++ ++Y     +  T +P  V+IA G ++ 
Sbjct: 6   ITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLF 65

Query: 73  LLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQ 132
           ++G  GC AT R S   L                           ++N    + +K  K 
Sbjct: 66  IIGLIGCCATIRESRCGLAT-------------------------VENEVDRSIQKVYKT 100

Query: 133 YNSTG-DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSE---KGFPKSCCK--LEDCTPQ 186
           YN T  D  S A+D +Q  LHCCG+ +Y DW +T+++ E   +  P SCC+    +C   
Sbjct: 101 YNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGS 160

Query: 187 -RDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLA-YCLSRAITNNQYEI 244
                 +  EGC   V+  ++  M  V   +   A  QL+G+  A   L R   +  YE+
Sbjct: 161 LAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYEL 220

Query: 245 V 245
           +
Sbjct: 221 L 221


>gi|4502693 CD9 antigen [Homo sapiens]
          Length = 228

 Score = 87.8 bits (216), Expect = 8e-18
 Identities = 52/235 (22%), Positives = 107/235 (45%), Gaps = 27/235 (11%)

Query: 16  CFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVP--------FVLIAT 67
           C K +L  + FIFW+ G+ +LA+G+W  +  ++    + E+ TN          ++LI  
Sbjct: 9   CIKYLLFGFNFIFWLAGIAVLAIGLW--LRFDSQTKSIFEQETNNNNSSFYTGVYILIGA 66

Query: 68  GTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYE 127
           G +++L+G  GC    + S  ML L+  FL ++F +E+ AAI G+  + E+    +  Y+
Sbjct: 67  GALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYK 126

Query: 128 KALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQR 187
               +  +  + +   +  I   L+CCG+    +                  + D  P++
Sbjct: 127 DTYNKLKTKDEPQRETLKAIHYALNCCGLAGGVEQF----------------ISDICPKK 170

Query: 188 DA-DKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQ 241
           D  +    + C   +  + +++  ++  +  G+A   + G+  +  L  AI  N+
Sbjct: 171 DVLETFTVKSCPDAIKEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRNR 225


>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.1 bits (209), Expect = 5e-17
 Identities = 47/163 (28%), Positives = 84/163 (51%), Gaps = 4/163 (2%)

Query: 18  KSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNE-KATNVPFVLIATGTVIILLGT 76
           K ++  +  +FW+ G  +L VGIW   +  ++ +L +   + +   +LI TG  ++ +G 
Sbjct: 10  KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIGF 69

Query: 77  FGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNST 136
            GC    + +  +L  + + L LVFL+E   AI+ F +  +I    + + +K L  Y + 
Sbjct: 70  VGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGTQ 129

Query: 137 GDY-RSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCC 178
           G+   ++A   IQ    CCGV++Y DW +   Y+    P SCC
Sbjct: 130 GNVGLTNAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCC 170


>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.1 bits (209), Expect = 5e-17
 Identities = 47/163 (28%), Positives = 84/163 (51%), Gaps = 4/163 (2%)

Query: 18  KSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNE-KATNVPFVLIATGTVIILLGT 76
           K ++  +  +FW+ G  +L VGIW   +  ++ +L +   + +   +LI TG  ++ +G 
Sbjct: 10  KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIGF 69

Query: 77  FGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNST 136
            GC    + +  +L  + + L LVFL+E   AI+ F +  +I    + + +K L  Y + 
Sbjct: 70  VGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGTQ 129

Query: 137 GDY-RSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCC 178
           G+   ++A   IQ    CCGV++Y DW +   Y+    P SCC
Sbjct: 130 GNVGLTNAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCC 170


>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.1 bits (209), Expect = 5e-17
 Identities = 47/163 (28%), Positives = 84/163 (51%), Gaps = 4/163 (2%)

Query: 18  KSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNE-KATNVPFVLIATGTVIILLGT 76
           K ++  +  +FW+ G  +L VGIW   +  ++ +L +   + +   +LI TG  ++ +G 
Sbjct: 10  KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIGF 69

Query: 77  FGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNST 136
            GC    + +  +L  + + L LVFL+E   AI+ F +  +I    + + +K L  Y + 
Sbjct: 70  VGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGTQ 129

Query: 137 GDY-RSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCC 178
           G+   ++A   IQ    CCGV++Y DW +   Y+    P SCC
Sbjct: 130 GNVGLTNAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCC 170


>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.1 bits (209), Expect = 5e-17
 Identities = 47/163 (28%), Positives = 84/163 (51%), Gaps = 4/163 (2%)

Query: 18  KSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNE-KATNVPFVLIATGTVIILLGT 76
           K ++  +  +FW+ G  +L VGIW   +  ++ +L +   + +   +LI TG  ++ +G 
Sbjct: 10  KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIGF 69

Query: 77  FGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNST 136
            GC    + +  +L  + + L LVFL+E   AI+ F +  +I    + + +K L  Y + 
Sbjct: 70  VGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGTQ 129

Query: 137 GDY-RSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCC 178
           G+   ++A   IQ    CCGV++Y DW +   Y+    P SCC
Sbjct: 130 GNVGLTNAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCC 170


>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.1 bits (209), Expect = 5e-17
 Identities = 47/163 (28%), Positives = 84/163 (51%), Gaps = 4/163 (2%)

Query: 18  KSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNE-KATNVPFVLIATGTVIILLGT 76
           K ++  +  +FW+ G  +L VGIW   +  ++ +L +   + +   +LI TG  ++ +G 
Sbjct: 10  KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIGF 69

Query: 77  FGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNST 136
            GC    + +  +L  + + L LVFL+E   AI+ F +  +I    + + +K L  Y + 
Sbjct: 70  VGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGTQ 129

Query: 137 GDY-RSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCC 178
           G+   ++A   IQ    CCGV++Y DW +   Y+    P SCC
Sbjct: 130 GNVGLTNAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCC 170


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.140    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,444,273
Number of Sequences: 37866
Number of extensions: 335060
Number of successful extensions: 1188
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1038
Number of HSP's gapped (non-prelim): 71
length of query: 245
length of database: 18,247,518
effective HSP length: 100
effective length of query: 145
effective length of database: 14,460,918
effective search space: 2096833110
effective search space used: 2096833110
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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