Search of human proteins with 4506925

Search of human proteins with 4506925

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506925 SH3 domain binding glutamic acid-rich protein like
[Homo sapiens]
         (114 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506925 SH3 domain binding glutamic acid-rich protein like [H...   230   2e-61
gi|239757584 PREDICTED: similar to SH3-binding domain and glutam...   154   2e-38
gi|6677929 SH3-binding domain and glutamic acid-rich protein iso...   154   2e-38
gi|13899317 SH3 domain binding glutamic acid-rich protein like 2...   136   3e-33
gi|48762712 SH3-binding domain and glutamic acid-rich protein is...    85   1e-17
gi|13775198 SH3 domain binding glutamic acid-rich protein like 3...    57   2e-09
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    28   2.0  
gi|95113651 glutaredoxin 3 [Homo sapiens]                              27   2.7  
gi|4502431 bone morphogenetic protein receptor, type IB precurso...    27   3.5  
gi|153085395 histone deacetylase 4 [Homo sapiens]                      27   3.5  
gi|155969714 nuclear protein,  ataxia-telangiectasia locus [Homo...    27   4.6  
gi|219689136 coiled-coil domain containing 68 [Homo sapiens]           26   5.9  
gi|13376818 coiled-coil domain containing 68 [Homo sapiens]            26   5.9  
gi|118600969 C-type lectin domain family 17, member A [Homo sapi...    26   5.9  
gi|51873049 hypothetical protein LOC8603 [Homo sapiens]                26   7.8  
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap...    26   7.8  

>gi|4506925 SH3 domain binding glutamic acid-rich protein like [Homo
           sapiens]
          Length = 114

 Score =  230 bits (587), Expect = 2e-61
 Identities = 114/114 (100%), Positives = 114/114 (100%)

Query: 1   MVIRVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPA 60
           MVIRVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPA
Sbjct: 1   MVIRVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPA 60

Query: 61  TGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAEVQAKQQA 114
           TGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAEVQAKQQA
Sbjct: 61  TGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAEVQAKQQA 114


>gi|239757584 PREDICTED: similar to SH3-binding domain and glutamic
           acid-rich protein [Homo sapiens]
          Length = 218

 Score =  154 bits (388), Expect = 2e-38
 Identities = 70/107 (65%), Positives = 88/107 (82%)

Query: 1   MVIRVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPA 60
           MVI+V++A+SSGS AI+KKQQ+V+GFLEANKI F+E DIA +E+NR+WMRENVP   +P 
Sbjct: 64  MVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKELDIAGDEDNRRWMRENVPGEKKPQ 123

Query: 61  TGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAE 107
            G PLPPQIFNE QY GD+D+FF A+E N +Y+FLGL  PP SK +E
Sbjct: 124 NGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPDSKGSE 170


>gi|6677929 SH3-binding domain and glutamic acid-rich protein
           isoform a [Homo sapiens]
          Length = 239

 Score =  154 bits (388), Expect = 2e-38
 Identities = 70/107 (65%), Positives = 88/107 (82%)

Query: 1   MVIRVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPA 60
           MVI+V++A+SSGS AI+KKQQ+V+GFLEANKI F+E DIA +E+NR+WMRENVP   +P 
Sbjct: 64  MVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKELDIAGDEDNRRWMRENVPGEKKPQ 123

Query: 61  TGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAE 107
            G PLPPQIFNE QY GD+D+FF A+E N +Y+FLGL  PP SK +E
Sbjct: 124 NGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPDSKGSE 170


>gi|13899317 SH3 domain binding glutamic acid-rich protein like 2
           [Homo sapiens]
          Length = 107

 Score =  136 bits (343), Expect = 3e-33
 Identities = 67/104 (64%), Positives = 80/104 (76%)

Query: 1   MVIRVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPA 60
           MVIRV+IASSSG  AIKKKQQDV+ FLEANKI FEE DI  +EE R+WM +NVP   +P 
Sbjct: 1   MVIRVFIASSSGFVAIKKKQQDVVRFLEANKIEFEEVDITMSEEQRQWMYKNVPPEKKPT 60

Query: 61  TGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSK 104
            G PLPPQIFN  +Y GDYD+FFE++E+N V++FLGL     SK
Sbjct: 61  QGNPLPPQIFNGDRYCGDYDSFFESKESNTVFSFLGLKPRLASK 104


>gi|48762712 SH3-binding domain and glutamic acid-rich protein
           isoform b [Homo sapiens]
          Length = 128

 Score = 85.1 bits (209), Expect = 1e-17
 Identities = 37/59 (62%), Positives = 44/59 (74%)

Query: 49  MRENVPENSRPATGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAE 107
           MRENVP   +P  G PLPPQIFNE QY GD+D+FF A+E N +Y+FLGL  PP SK +E
Sbjct: 1   MRENVPGEKKPQNGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPDSKGSE 59


>gi|13775198 SH3 domain binding glutamic acid-rich protein like 3
          [Homo sapiens]
          Length = 93

 Score = 57.4 bits (137), Expect = 2e-09
 Identities = 37/97 (38%), Positives = 49/97 (50%), Gaps = 10/97 (10%)

Query: 3  IRVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPATG 62
          +RVY  S +GS  IK +Q +V   L+  +I ++  DI+ +   R  MR           G
Sbjct: 4  LRVYSTSVTGSREIKSQQSEVTRILDGKRIQYQLVDISQDNALRDEMRA--------LAG 55

Query: 63 YP--LPPQIFNESQYRGDYDAFFEARENNAVYAFLGL 97
           P   PPQI N  QY GDY+ F EA E N +  FL L
Sbjct: 56 NPKATPPQIVNGDQYCGDYELFVEAVEQNTLQEFLKL 92


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 1/62 (1%)

Query: 7   IASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANE-ENRKWMRENVPENSRPATGYPL 65
           + S  G +   KKQ+  L   E  K   EEKD    E E R    E +P   +     P 
Sbjct: 344 VGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPP 403

Query: 66  PP 67
           PP
Sbjct: 404 PP 405


>gi|95113651 glutaredoxin 3 [Homo sapiens]
          Length = 335

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 17/75 (22%), Positives = 34/75 (45%), Gaps = 8/75 (10%)

Query: 21  QDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPATGYPLPPQIFNESQYRGDYD 80
           + +L  L +  + +E  DI  +EE R+ ++          + +P  PQ++ + +  G  D
Sbjct: 265 KQILEILNSTGVEYETFDILEDEEVRQGLKAY--------SNWPTYPQLYVKGELVGGLD 316

Query: 81  AFFEARENNAVYAFL 95
              E +EN  +   L
Sbjct: 317 IVKELKENGELLPIL 331


>gi|4502431 bone morphogenetic protein receptor, type IB precursor
           [Homo sapiens]
          Length = 502

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 10/34 (29%), Positives = 20/34 (58%)

Query: 52  NVPENSRPATGYPLPPQIFNESQYRGDYDAFFEA 85
           ++P N+R  T   +PP++ +ES  R  + ++  A
Sbjct: 365 DIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMA 398


>gi|153085395 histone deacetylase 4 [Homo sapiens]
          Length = 1084

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 19/94 (20%)

Query: 20  QQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPATGYPLPPQIFNESQYRGDY 79
           QQ    FLE +K  F+++ +  N+         +P+ S PA      P+   E       
Sbjct: 483 QQQHQQFLEKHKQQFQQQQLQMNKI--------IPKPSEPARQPESHPEETEE------- 527

Query: 80  DAFFEARENNAVYAFLGLTAPPGSKEAEVQAKQQ 113
               E RE+ A+     L   PG KEA  QA  Q
Sbjct: 528 ----ELREHQALLDEPYLDRLPGQKEAHAQAGVQ 557


>gi|155969714 nuclear protein,  ataxia-telangiectasia locus [Homo
           sapiens]
          Length = 1427

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 10/17 (58%), Positives = 12/17 (70%)

Query: 53  VPENSRPATGYPLPPQI 69
           +P NS P T  PLPPQ+
Sbjct: 890 LPGNSAPMTAQPLPPQL 906


>gi|219689136 coiled-coil domain containing 68 [Homo sapiens]
          Length = 335

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 1/58 (1%)

Query: 4   RVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPAT 61
           R++    + S  ++KKQ+D    L+ NK+  E+K +  + EN   + E + E     T
Sbjct: 133 RLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQK-LKQHVENLNQVAEKLEEKHSQIT 189


>gi|13376818 coiled-coil domain containing 68 [Homo sapiens]
          Length = 335

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 1/58 (1%)

Query: 4   RVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPAT 61
           R++    + S  ++KKQ+D    L+ NK+  E+K +  + EN   + E + E     T
Sbjct: 133 RLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQK-LKQHVENLNQVAEKLEEKHSQIT 189


>gi|118600969 C-type lectin domain family 17, member A [Homo
           sapiens]
          Length = 289

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 15/47 (31%), Positives = 20/47 (42%), Gaps = 8/47 (17%)

Query: 61  TGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAE 107
           TGYP PP    E +   DY+        N+   +  L   PG+ E E
Sbjct: 8   TGYPDPPGTMEEEEEDDDYE--------NSTPPYKDLPPKPGTMEEE 46


>gi|51873049 hypothetical protein LOC8603 [Homo sapiens]
          Length = 1224

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 15/54 (27%), Positives = 23/54 (42%), Gaps = 3/54 (5%)

Query: 14   TAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPATGYPLPP 67
            T  K K  D++   E  +   EE+ + +N  N+K +     E S P    P  P
Sbjct: 1080 TESKAKVVDLMSITEQKR---EERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSP 1130


>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
          Length = 2365

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 11/26 (42%), Positives = 12/26 (46%)

Query: 43   EENRKWMRENVPENSRPATGYPLPPQ 68
            E    W  E  PE  R   G PLPP+
Sbjct: 1372 EPPHPWSPEKRPEGDRQLQGSPLPPR 1397


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,544,322
Number of Sequences: 37866
Number of extensions: 192162
Number of successful extensions: 408
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 398
Number of HSP's gapped (non-prelim): 16
length of query: 114
length of database: 18,247,518
effective HSP length: 84
effective length of query: 30
effective length of database: 15,066,774
effective search space: 452003220
effective search space used: 452003220
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.