Guide to the Human Genome
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Search of human proteins with 4506875

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506875 selectin L precursor [Homo sapiens]
         (372 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506875 selectin L precursor [Homo sapiens]                        818   0.0  
gi|157419154 selectin P precursor [Homo sapiens]                      359   3e-99
gi|187960042 selectin E precursor [Homo sapiens]                      339   2e-93
gi|148886654 polydom [Homo sapiens]                                    95   1e-19
gi|90991712 CD207 antigen, langerin [Homo sapiens]                     68   1e-11
gi|62739188 complement factor H isoform b precursor [Homo sapiens]     66   4e-11
gi|62739186 complement factor H isoform a precursor [Homo sapiens]     66   4e-11
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap...    66   4e-11
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa...    66   4e-11
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap...    66   4e-11
gi|223029384 CD209 molecule isoform 7 [Homo sapiens]                   66   6e-11
gi|223029380 CD209 molecule isoform 5 [Homo sapiens]                   66   6e-11
gi|4505245 mannose receptor C type 1 precursor [Homo sapiens]          65   1e-10
gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens]           65   1e-10
gi|20149533 Fc fragment of IgE, low affinity II, receptor for (C...    64   2e-10
gi|223029517 CD209 molecule isoform 8 [Homo sapiens]                   64   3e-10
gi|223029386 CD209 molecule isoform 3 [Homo sapiens]                   64   3e-10
gi|223029382 CD209 molecule isoform 6 [Homo sapiens]                   64   3e-10
gi|10863957 CD209 molecule isoform 1 [Homo sapiens]                    64   3e-10
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]           64   3e-10
gi|33667103 C-type lectin, superfamily member 14 isoform 1 [Homo...    63   4e-10
gi|53832016 C-type lectin, superfamily member 14 isoform 2 [Homo...    63   4e-10
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi...    62   1e-09
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi...    62   1e-09
gi|7657619 sushi-repeat-containing protein, X-linked 2 [Homo sap...    61   2e-09
gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens]     60   2e-09
gi|18426875 asialoglycoprotein receptor 2 isoform b [Homo sapiens]     60   2e-09
gi|18426873 asialoglycoprotein receptor 2 isoform a [Homo sapiens]     60   2e-09
gi|4502253 asialoglycoprotein receptor 2 isoform a [Homo sapiens]      60   2e-09
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ...    60   4e-09

>gi|4506875 selectin L precursor [Homo sapiens]
          Length = 372

 Score =  818 bits (2114), Expect = 0.0
 Identities = 372/372 (100%), Positives = 372/372 (100%)

Query: 1   MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDN 60
           MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDN
Sbjct: 1   MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDN 60

Query: 61  YTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPN 120
           YTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPN
Sbjct: 61  YTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPN 120

Query: 121 NKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTC 180
           NKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTC
Sbjct: 121 NKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTC 180

Query: 181 NCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETT 240
           NCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETT
Sbjct: 181 NCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETT 240

Query: 241 CGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKK 300
           CGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKK
Sbjct: 241 CGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKK 300

Query: 301 TICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKK 360
           TICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKK
Sbjct: 301 TICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKK 360

Query: 361 GKKSKRSMNDPY 372
           GKKSKRSMNDPY
Sbjct: 361 GKKSKRSMNDPY 372


>gi|157419154 selectin P precursor [Homo sapiens]
          Length = 830

 Score =  359 bits (921), Expect = 3e-99
 Identities = 159/310 (51%), Positives = 206/310 (66%)

Query: 8   QSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAI 67
           Q  QR ++ I +L  ++ L  +         WTYHYS K  +W  +R++C++ YTDLVAI
Sbjct: 11  QRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYCQNRYTDLVAI 70

Query: 68  QNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNKED 127
           QNK EI+YL K LP+  SYYWIGIRK    WTWVGT K+LT EAENW D EPNNK+N ED
Sbjct: 71  QNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADNEPNNKRNNED 130

Query: 128 CVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYY 187
           CVEIYIK     GKWND+ C K K ALCYTASCQ  SCS  GEC+E I NYTC+C  G+Y
Sbjct: 131 CVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFY 190

Query: 188 GPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNW 247
           GP+C++V +C  LE P+   M+C+HPLGNFSF+SQC+F C++G  + G  +  C   G W
Sbjct: 191 GPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIW 250

Query: 248 SSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG 307
           ++  P C   QC PL  P+ G M C H   +F   S+C+F C EG  L+G +   C +SG
Sbjct: 251 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 310

Query: 308 IWSNPSPICQ 317
           +W+ P+P+C+
Sbjct: 311 VWTAPAPVCK 320



 Score =  131 bits (330), Expect = 9e-31
 Identities = 58/131 (44%), Positives = 81/131 (61%), Gaps = 1/131 (0%)

Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS 248
           P C+  +QC+ LEAP  GTMDC HPL  F++ S C F C  G  + G++   C   G+WS
Sbjct: 317 PVCK-AVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWS 375

Query: 249 SPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGI 308
           +P PTC+ I CEPL +P  G M+CS  L +F + + C+F C+EG  L G     C++ G 
Sbjct: 376 APLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQ 435

Query: 309 WSNPSPICQKL 319
           W+ P+P+CQ L
Sbjct: 436 WTAPAPVCQAL 446



 Score =  128 bits (322), Expect = 7e-30
 Identities = 66/178 (37%), Positives = 98/178 (55%), Gaps = 8/178 (4%)

Query: 145 DACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYYG---PQCQFVIQCEPLE 201
           D  H L  A  Y +SC+ + C   G  V  ++   C  D G++    P C+  I CEPLE
Sbjct: 336 DCVHPL-TAFAYGSSCK-FECQP-GYRVRGLDMLRC-IDSGHWSAPLPTCE-AISCEPLE 390

Query: 202 APELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEP 261
           +P  G+MDC+  L  F + + C+F C+EG  L G +   C   G W++P P CQ +QC+ 
Sbjct: 391 SPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQD 450

Query: 262 LSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
           L  P+   +NCSHP  +F + S C+F C+EG  L+G     C ++G W++  P CQ +
Sbjct: 451 LPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAI 508



 Score =  126 bits (316), Expect = 4e-29
 Identities = 72/221 (32%), Positives = 99/221 (44%), Gaps = 27/221 (12%)

Query: 125 KEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHG--ECVEIIN--NYTC 180
           K +C   Y  R  D  +  D          C   SC+P     HG  +C   +    Y  
Sbjct: 351 KFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDT 410

Query: 181 NC-------------------DVGYY---GPQCQFVIQCEPLEAPELGTMDCTHPLGNFS 218
           NC                   ++G +    P CQ  +QC+ L  P    ++C+HP G F 
Sbjct: 411 NCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQ-ALQCQDLPVPNEARVNCSHPFGAFR 469

Query: 219 FSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLAS 278
           + S C+F+C+EG  L G     C   GNW+S  P CQ I C PL +P  G M C  PL S
Sbjct: 470 YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGS 529

Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
            S+ S C FIC EG  L G ++  C  SG W++  P+C+ +
Sbjct: 530 SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAI 570



 Score =  114 bits (285), Expect = 1e-25
 Identities = 53/129 (41%), Positives = 70/129 (54%), Gaps = 1/129 (0%)

Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS 248
           P+CQ  I C PL +P+ GTM C  PLG+ S+ S C F C EG +L+G E   C   G W+
Sbjct: 503 PECQ-AIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWT 561

Query: 249 SPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGI 308
              P C+ I+C  L AP+ G ++CS     F+  S C F C  G +L G     C +SG 
Sbjct: 562 DSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGR 621

Query: 309 WSNPSPICQ 317
           WS   P C+
Sbjct: 622 WSATPPTCK 630



 Score =  106 bits (265), Expect = 3e-23
 Identities = 63/206 (30%), Positives = 88/206 (42%), Gaps = 27/206 (13%)

Query: 139 AGKWNDDA--CHKLKAALCYTASCQPWSCSG-----------HGEC-----VEIINNYTC 180
           +G+W D    C  +K    +        CS            H  C     +E  NN  C
Sbjct: 557 SGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVEC 616

Query: 181 NCDVGYYG--PQCQFV-------IQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGT 231
                +    P C+ +       +QC  L  P  GTM C H  G F F++ C F C+ G 
Sbjct: 617 TTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGF 676

Query: 232 NLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSE 291
            L G    +C P G W++  P C+ ++C  L       MNCS+   +FS+ S C+F C E
Sbjct: 677 TLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLE 736

Query: 292 GTELIGKKKTICESSGIWSNPSPICQ 317
           G  L G  +T C+ +G WS   P CQ
Sbjct: 737 GQLLNGSAQTACQENGHWSTTVPTCQ 762


>gi|187960042 selectin E precursor [Homo sapiens]
          Length = 610

 Score =  339 bits (870), Expect = 2e-93
 Identities = 147/279 (52%), Positives = 187/279 (67%)

Query: 39  WTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIW 98
           W+Y+ S + M +  A  +C+  YT LVAIQNK EIEYL   L +S SYYWIGIRK+  +W
Sbjct: 22  WSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVW 81

Query: 99  TWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTA 158
            WVGT K LTEEA+NW  GEPNN++  EDCVEIYIKR KD G WND+ C K K ALCYTA
Sbjct: 82  VWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTA 141

Query: 159 SCQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFS 218
           +C   SCSGHGECVE INNYTC CD G+ G +C+ ++ C  LE+PE G++ C+HPLGNFS
Sbjct: 142 ACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFS 201

Query: 219 FSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLAS 278
           ++S C+ SC  G   + +E   C   G WS+P P C V++C+ ++ P  G + C     S
Sbjct: 202 YNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGS 261

Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQ 317
           F + + CTF C EG EL+G +   C SSG W N  P C+
Sbjct: 262 FPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK 300



 Score =  114 bits (284), Expect = 2e-25
 Identities = 55/146 (37%), Positives = 79/146 (54%), Gaps = 4/146 (2%)

Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPL-GNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNW 247
           P C+   QC  L  PE G M+C     G+F + S C FSC +G  L G +   CGP G W
Sbjct: 360 PVCE-AFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEW 418

Query: 248 SSPEPTCQVIQCEPLSAPDLGIMNCSH-PLASFSFTSACTFICSEGTELIGKKKTICESS 306
            + +PTC+ ++C+ +  P  G++ C+H P+  F++ S+C F C EG EL G  +  C S 
Sbjct: 419 DNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQ 478

Query: 307 GIWSNPSPICQKLDKSFSMIKEGDYN 332
           G W+   P CQ + K  S+   G  N
Sbjct: 479 GQWTEEVPSCQVV-KCSSLAVPGKIN 503



 Score =  103 bits (258), Expect = 2e-22
 Identities = 49/131 (37%), Positives = 68/131 (51%), Gaps = 3/131 (2%)

Query: 189 PQCQFVIQCEPLEAPELGTMDCTH-PLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNW 247
           P C+  + C  +  P+ G++ C+H P G F+F S C F+C EG  L G  +  C   G W
Sbjct: 297 PTCK-AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQW 355

Query: 248 SSPEPTCQVIQCEPLSAPDLGIMNC-SHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
           +   P C+  QC  LS P+ G MNC      SF + S+C F C +G  L G K+  C  +
Sbjct: 356 TQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPT 415

Query: 307 GIWSNPSPICQ 317
           G W N  P C+
Sbjct: 416 GEWDNEKPTCE 426



 Score =  103 bits (258), Expect = 2e-22
 Identities = 60/178 (33%), Positives = 89/178 (50%), Gaps = 16/178 (8%)

Query: 189 PQCQFVIQCEPLEAPELGTMDCTH-PLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNW 247
           P C+  ++C+ +  P  G + C H P+G F++ S CAFSC EG  L G  +  C   G W
Sbjct: 423 PTCE-AVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQW 481

Query: 248 SSPEPTCQVIQCEPLSAPDLGIMNCS-HPLASFSFTSACTFICSEGTELIGKKKTICESS 306
           +   P+CQV++C  L+ P    M+CS  P+    F + C F C EG  L G     C ++
Sbjct: 482 TEEVPSCQVVKCSSLAVPGKINMSCSGEPV----FGTVCKFACPEGWTLNGSAARTCGAT 537

Query: 307 GIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLA-FIIWLARRLKKGKK 363
           G WS   P C+   +S          PL   ++    +   LA F++WL + L+K KK
Sbjct: 538 GHWSGLLPTCEAPTES--------NIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKK 587


>gi|148886654 polydom [Homo sapiens]
          Length = 3571

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 61/198 (30%), Positives = 91/198 (45%), Gaps = 17/198 (8%)

Query: 138  DAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYYGP--QCQFVI 195
            D G WN  +   L    C   S     CS H  C+ +  +Y C+C   Y G    C   I
Sbjct: 1732 DNGSWNGVSPSCLDVDECAVGS----DCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPI 1787

Query: 196  QCEPLEAPELGTMDCTHPLGN-FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC 254
            +C+    PE G     H  G  ++  ++  FSC EG  L G+ + TC   G W+   P C
Sbjct: 1788 KCKAPGNPENG-----HSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYC 1842

Query: 255  QVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSP 314
            + + C   + P+ G   C   LA F+F S  T+ C++G  L G K++ C ++  WS+  P
Sbjct: 1843 KAVSCGKPAIPENG---CIEELA-FTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPP 1898

Query: 315  ICQKLD-KSFSMIKEGDY 331
            +C+ +   S   I  G Y
Sbjct: 1899 VCEPVKCSSPENINNGKY 1916



 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 8/179 (4%)

Query: 158 ASCQPWSCSGHGECVEIINNYTCNCDVGYY--GPQCQFVIQCEPLEAPELGTMDCTHPLG 215
           +SC P     H       +   C C  GY   G  C+ V  C  L+ PE G         
Sbjct: 338 SSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELV-HCPALKPPENGYF--IQNTC 394

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
           N  F++ C   C  G +L G     C P G WS  E  C+V  C  L  P  G ++CS  
Sbjct: 395 NNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCS-- 452

Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC-QKLDKSFSMIKEGDYNP 333
                + + C   C EG  L G  K  C+ +  W  P P C ++   +F M K+   +P
Sbjct: 453 TREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISP 511



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 10/133 (7%)

Query: 189  PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS 248
            P C+ V+ C P   P L +     P     F S   +SC  G  L G   T C P G WS
Sbjct: 2374 PVCKIVL-CTP---PPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWS 2429

Query: 249  SPEPTCQVIQC-EPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG 307
            SP P C  ++C +P   P+ GI++    +   ++ S   + C  G EL+G   T+C  +G
Sbjct: 2430 SPLPECVPVECPQPEEIPN-GIID----VQGLAYLSTALYTCKPGFELVGNTTTLCGENG 2484

Query: 308  IWSNPSPICQKLD 320
             W    P C+ ++
Sbjct: 2485 HWLGGKPTCKAIE 2497



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 39/128 (30%), Positives = 65/128 (50%), Gaps = 5/128 (3%)

Query: 195  IQCEPLEAPELGTMDCTHPLG-NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPT 253
            IQC P+   E  ++   +  G N+SF +  A+SC++G  + G +++TC   G WSSP PT
Sbjct: 2139 IQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPT 2198

Query: 254  CQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPS 313
            C  + C      + G +   H      F S   + C+ G + +G    +C+++  W + S
Sbjct: 2199 CHPVSCGEPPKVENGFL--EHTTGRI-FESEVRYQCNPGYKSVGSPVFVCQANRHWHSES 2255

Query: 314  PI-CQKLD 320
            P+ C  LD
Sbjct: 2256 PLMCVPLD 2263



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 39/148 (26%), Positives = 68/148 (45%), Gaps = 15/148 (10%)

Query: 176  NNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPL---GNFSFSSQCAFSCSEGTN 232
            + +TC  D  ++  +    I C P + P     + TH L    +FS + Q + SC+EG  
Sbjct: 3159 DTFTCQKDGRWFPER----ISCSPKKCPL--PENITHILVHGDDFSVNRQVSVSCAEGYT 3212

Query: 233  LTGIEETTCGPFGNWSSP--EPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICS 290
              G+  + C   G W  P  + +C  + C    +P+ G +  S     ++F S   + C 
Sbjct: 3213 FEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGS----KYTFESTIIYQCE 3268

Query: 291  EGTELIGKKKTICESSGIWSNPSPICQK 318
             G EL G ++ +C+ +  WS    IC++
Sbjct: 3269 PGYELEGNRERVCQENRQWSGGVAICKE 3296



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 36/122 (29%), Positives = 51/122 (41%), Gaps = 4/122 (3%)

Query: 196  QCEPLEAPELGTMDCTHPLGNFSFS-SQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC 254
            +C P + PE   ++    L   +       FSC EG  L G     C P   W+   P C
Sbjct: 2317 KCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVC 2376

Query: 255  QVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSP 314
            +++ C P   P L       P ++  F S   + C  G  L G   T+C+  G WS+P P
Sbjct: 2377 KIVLCTP---PPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLP 2433

Query: 315  IC 316
             C
Sbjct: 2434 EC 2435



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 36/116 (31%), Positives = 48/116 (41%), Gaps = 8/116 (6%)

Query: 204  ELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLS 263
            E GT++ T    +F         C +G  L G+ E TC   G WSS  P C+   C  L 
Sbjct: 3013 EYGTVNGT----DFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP 3068

Query: 264  APDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
                 I N      S    +  T+ C  G  + G    IC   G+WS P P+C+ L
Sbjct: 3069 M----IPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 3120



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 33/101 (32%), Positives = 53/101 (52%), Gaps = 4/101 (3%)

Query: 217  FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPD-LGIMNCSHP 275
            F+  S  +F C EG  L    +  C   G W+   P+   IQC P+   +   IMN    
Sbjct: 2102 FAAGSVVSFKCMEGFVLNTSAKIECMRGGQWN---PSPMSIQCIPVRCGEPPSIMNGYAS 2158

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
             +++SF +   + C++G  + G+KK+ CE++G WS+P P C
Sbjct: 2159 GSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2199



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 9/134 (6%)

Query: 189  PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS 248
            P C   I+C+   APE G +  T      S  S   +SC  G  L G +   C     WS
Sbjct: 2710 PSC-ISIECDLPTAPENGFLRFTET----SMGSAVQYSCKPGHILAGSDLRLCLENRKWS 2764

Query: 249  SPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGI 308
               P C+ I C+  +     +MN S   +++++ S   + C  G  L G ++  C+    
Sbjct: 2765 GASPRCEAISCKKPNP----VMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKN 2820

Query: 309  WSNPSPICQKLDKS 322
            W    PIC  +D S
Sbjct: 2821 WDEDEPICIPVDCS 2834



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 37/119 (31%), Positives = 49/119 (41%), Gaps = 8/119 (6%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            ++ F  +  F C EG  L G  + TC   GNW +  P C+ + C P      G  N    
Sbjct: 2906 DYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPN---- 2961

Query: 276  LASFSFTSA--CTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYN 332
               FSF       + C  G +L G     C S+G WS  SP C     S  +I+ G  N
Sbjct: 2962 --GFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVN 3018



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 13/129 (10%)

Query: 196  QCEPLEAPEL-----GTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSP 250
            +C P+E P+      G +D    +   ++ S   ++C  G  L G   T CG  G+W   
Sbjct: 2434 ECVPVECPQPEEIPNGIID----VQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGG 2489

Query: 251  EPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWS 310
            +PTC+ I+C         I+N         +    T+ C+ G  L G     C  +G W 
Sbjct: 2490 KPTCKAIEC----LKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWD 2545

Query: 311  NPSPICQKL 319
              +P C  +
Sbjct: 2546 VDAPSCNAI 2554



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 217  FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL 276
            ++F  +  ++C+EG  L G     C   G+WS   P C  ++C   + P L   N     
Sbjct: 2849 YTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC--ATPPQLA--NGVTEG 2904

Query: 277  ASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLD 320
              + F    TF C EG  L G  K  C+S G W    P+C+ ++
Sbjct: 2905 LDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN 2948



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            NF + +  +++C+ G  L G     C   G W+   P+C  I+C+  +AP+ G +     
Sbjct: 2674 NFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLR---- 2729

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
                S  SA  + C  G  L G    +C  +  WS  SP C+ +
Sbjct: 2730 FTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAI 2773



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 31/103 (30%), Positives = 46/103 (44%), Gaps = 8/103 (7%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCE--PLSAPDLGIMNCS 273
            N+++ S   + C  G  L G E  TC    NW   EP C  + C   P+SA      N  
Sbjct: 2790 NYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSA------NGQ 2843

Query: 274  HPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
                 ++F     + C+EG  L G +  +C ++G WS  +P C
Sbjct: 2844 VRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC 2886



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 42/178 (23%), Positives = 68/178 (38%), Gaps = 32/178 (17%)

Query: 160  CQPWSCSG-----HGECV----EIINNYTCNCDVGY--YGPQCQFVIQCEPL-----EAP 203
            C+P  CS      +G+ +      ++  + +CD GY   GP    +I+C          P
Sbjct: 1900 CEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPS---IIECTASGIWDRAPP 1956

Query: 204  ELGTMDCTHPLG---------NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC 254
                + C  P           NF+F +   ++C EG  L G++   C   G WS  +  C
Sbjct: 1957 ACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQC 2016

Query: 255  QVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNP 312
              + C+     D      +H L    F     + CS+G  L    + +C + G W  P
Sbjct: 2017 LAVSCDEPPIVDHASPETAHRL----FGDIAFYYCSDGYSLADNSQLLCNAQGKWVPP 2070



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 14/127 (11%)

Query: 203  PELGTMDCTHPL----GNFSFSS-----QCAFSCSEGTNLTGIEETTCGPFGNWSSPEPT 253
            P    ++C  P     G FS++         +SC+ G  L G    TC   G+W    P+
Sbjct: 2491 PTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPS 2550

Query: 254  CQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPS 313
            C  I C+     + G +      A +S+ +   + C  G ++ G     CE SG WS+  
Sbjct: 2551 CNAIHCDSPQPIENGFVEG----ADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSI 2605

Query: 314  PICQKLD 320
            P C  +D
Sbjct: 2606 PTCMPID 2612



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 14/158 (8%)

Query: 164  SCSGHGECVEIINNYTCNCDVGYYGP----QCQFVIQCEPLEAPELGTMDCTHPLGNFSF 219
            SC+  G   E +N   C  D  +  P     C   + C   E+PE G +  +     ++F
Sbjct: 3206 SCA-EGYTFEGVNISVCQLDGTWEPPFSDESCS-PVSCGKPESPEHGFVVGS----KYTF 3259

Query: 220  SSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASF 279
             S   + C  G  L G  E  C     WS     C+  +CE      L  +N    + + 
Sbjct: 3260 ESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCE----TPLEFLNGKADIENR 3315

Query: 280  SFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQ 317
            +      + C+ G  L G  +  C  +G WS+P P+C+
Sbjct: 3316 TTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCK 3353



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 9/123 (7%)

Query: 197  CEPLE--APELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC 254
            CEP++  +PE    +  + L   ++ S  ++SC  G +L G     C   G W    P C
Sbjct: 1900 CEPVKCSSPE-NINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPAC 1958

Query: 255  QVIQC-EPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPS 313
             ++ C EP +  D  I        +F+F +  T+ C EG  L G     C + G WS   
Sbjct: 1959 HLVFCGEPPAIKDAVITG-----NNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSD 2013

Query: 314  PIC 316
              C
Sbjct: 2014 QQC 2016



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 4/95 (4%)

Query: 227  CSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACT 286
            C  G  L G     C   G W+ P P C+ I C  +  P   + N  H    F   S  T
Sbjct: 1658 CDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCG-VPPP---LENGFHSADDFYAGSTVT 1713

Query: 287  FICSEGTELIGKKKTICESSGIWSNPSPICQKLDK 321
            + C+ G  L+G  +  C  +G W+  SP C  +D+
Sbjct: 1714 YQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDE 1748



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 5/101 (4%)

Query: 217  FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL 276
            F      +  C EG  L G    TC P   W+     C+ I C P +  +  I    H  
Sbjct: 3374 FYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVH-- 3431

Query: 277  ASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQ 317
              + +    T+ C  G  L G  +++C  +G W++P PIC+
Sbjct: 3432 --YQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSP-PICR 3469



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 41/198 (20%), Positives = 69/198 (34%), Gaps = 58/198 (29%)

Query: 178  YTCNCDVGYYGPQCQFVIQCEP--LEAPELGTMDCTHPL---------GNFSFSSQCAFS 226
            Y+CN      GP     ++     ++AP    + C  P           ++S+ +   +S
Sbjct: 2522 YSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYS 2581

Query: 227  CSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCS------------- 273
            C  G  + G    TC   G WSS  PTC  I C     P +   +C+             
Sbjct: 2582 CFPGFQVAGHAMQTCEESG-WSSSIPTCMPIDCG--LPPHIDFGDCTKLKDDQGYFEQED 2638

Query: 274  ----------HP---------------------LASFSFTSACTFICSEGTELIGKKKTI 302
                      HP                      ++F + +  ++ C+ G EL+G    I
Sbjct: 2639 DMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLI 2698

Query: 303  CESSGIWSNPSPICQKLD 320
            C+  G W+  +P C  ++
Sbjct: 2699 CQEDGTWNGSAPSCISIE 2716



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 5/103 (4%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            NF   S+  F C+EG  L G    TC   G W+         +C P   P+  ++     
Sbjct: 2279 NFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNP----KCMPAKCPEPPLLENQLV 2334

Query: 276  LASFSF-TSACTFICSEGTELIGKKKTICESSGIWSNPSPICQ 317
            L   +      TF C EG  L G     C  S  W++  P+C+
Sbjct: 2335 LKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2377



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 37/125 (29%), Positives = 49/125 (39%), Gaps = 7/125 (5%)

Query: 196  QCEPLEAPELGTMDCTHP-LGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPE--- 251
            QC  +   E   +D   P   +  F     + CS+G +L    +  C   G W  PE   
Sbjct: 2015 QCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQD 2074

Query: 252  -PTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWS 310
             P C    CE   +    I+  S   A F+  S  +F C EG  L    K  C   G W 
Sbjct: 2075 MPRCIAHFCEKPPSVSYSILE-SVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQW- 2132

Query: 311  NPSPI 315
            NPSP+
Sbjct: 2133 NPSPM 2137



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 5/96 (5%)

Query: 225  FSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCE-PLSAPDLGIMNCSHPLASFSFTS 283
            +SC+ G +L G  E  C   G WS P P C+   C  P   P+  +++       F    
Sbjct: 3323 YSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLS----EKEFYVDQ 3378

Query: 284  ACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
              +  C EG  L G     C     W+  S  C+K+
Sbjct: 3379 NVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKI 3414



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 32/145 (22%), Positives = 49/145 (33%), Gaps = 41/145 (28%)

Query: 212  HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC----------------- 254
            H   +F   S   + C+ G  L G     C   G+W+   P+C                 
Sbjct: 1701 HSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHAS 1760

Query: 255  -------QVIQCEPLSAPDLGIMNCSHPLAS---------------FSFTSACTFICSEG 292
                    +  C P    D    NC+ P+                 ++  +  TF C EG
Sbjct: 1761 CLNVDGSYICSCVPPYTGD--GKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEG 1818

Query: 293  TELIGKKKTICESSGIWSNPSPICQ 317
             +L+G  K  C  SG W++  P C+
Sbjct: 1819 YQLMGVTKITCLESGEWNHLIPYCK 1843



 Score = 37.0 bits (84), Expect = 0.029
 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 8/89 (8%)

Query: 148  HKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVI-QCEPLEAPELG 206
            H++ + + +     P  C   G C ++   Y C C +GY G +C+  I +C PL  P L 
Sbjct: 1187 HEISSQVFHECFFNP--CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPL--PCLN 1242

Query: 207  TMDCTHPLGNFSFSSQCAFS---CSEGTN 232
               C   +G F       ++   C E  N
Sbjct: 1243 NGVCKDLVGEFICECPSGYTGQRCEENIN 1271



 Score = 37.0 bits (84), Expect = 0.029
 Identities = 12/33 (36%), Positives = 19/33 (57%)

Query: 160  CQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQ 192
            CQ   C     CV+ +N+Y+C C  G+ G +C+
Sbjct: 1387 CQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 23/86 (26%), Positives = 34/86 (39%), Gaps = 5/86 (5%)

Query: 225  FSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSA 284
            +SC  G  + G  +  C   G WS P P C+ + C   S P   + N      + ++ S 
Sbjct: 3088 YSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCG--SPP--SVANAVATGEAHTYESE 3143

Query: 285  CTFICSEGTELIGKKKTI-CESSGIW 309
                C EG  +     T  C+  G W
Sbjct: 3144 VKLRCLEGYTMDTDTDTFTCQKDGRW 3169



 Score = 32.7 bits (73), Expect = 0.54
 Identities = 17/58 (29%), Positives = 23/58 (39%), Gaps = 1/58 (1%)

Query: 160  CQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNF 217
            C    C   G CV+ +  Y C C  G+ G  C+  +  E    P L    C   +G F
Sbjct: 1273 CSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVN-ECQSNPCLNNAVCEDQVGGF 1329



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 11/37 (29%), Positives = 18/37 (48%)

Query: 283  SACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
            S     C  G +L+G     C + G W+ P P C+++
Sbjct: 1652 SKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERI 1688



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 20/80 (25%), Positives = 33/80 (41%), Gaps = 6/80 (7%)

Query: 179  TCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLG-NFSFSSQCAFSCSEGTNLTGIE 237
            TCN D  +     Q   +CE +       ++     G ++ +     +SC  G  L G  
Sbjct: 3397 TCNPDETW----TQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFL 3452

Query: 238  ETTCGPFGNWSSPEPTCQVI 257
             + C   G W+SP P C+ +
Sbjct: 3453 RSVCLENGTWTSP-PICRAV 3471



 Score = 29.6 bits (65), Expect = 4.6
 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 11/108 (10%)

Query: 169 GECVEIINNYTCNCDVGYYGPQCQFVIQ-CEPLEAPELGTMDCTHPLGN--FSFSSQCAF 225
           G  +E  +  TC  +  + GP+ + V + C   + P+   +   H  G     F + C  
Sbjct: 469 GYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPK-DVIISPHNCGKQPAKFGTICYV 527

Query: 226 SCSEGTNLTGIEE-TTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNC 272
           SC +G  L+G++E   C   G W+      Q   C+ + AP +   NC
Sbjct: 528 SCRQGFILSGVKEMLRCTTSGKWN---VGVQAAVCKDVEAPQI---NC 569



 Score = 29.6 bits (65), Expect = 4.6
 Identities = 25/104 (24%), Positives = 37/104 (35%), Gaps = 5/104 (4%)

Query: 160  CQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSF 219
            CQ   C  +  C + +  + C C  G+ G +C   +  E L  P      C    G  SF
Sbjct: 1311 CQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVD-ECLSQPCKNGATCKD--GANSF 1367

Query: 220  SSQCAFSCSEGTNLTGIEETTCGPFGNWSS--PEPTCQVIQCEP 261
               CA   +       I E    P  N ++   E      +C+P
Sbjct: 1368 RCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQP 1411


>gi|90991712 CD207 antigen, langerin [Homo sapiens]
          Length = 328

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 8/118 (6%)

Query: 41  YHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIW 98
           Y++S  P  W  A +FC    + L ++ +++E E+L KT       YWIG+ K G  G W
Sbjct: 207 YYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTA--GGLIYWIGLTKAGMEGDW 264

Query: 99  TWV-GTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
           +WV  T  +  +    W  GEPNN  N E C  I   +      WND  C K    +C
Sbjct: 265 SWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNI---KAPSLQAWNDAPCDKTFLFIC 319


>gi|62739188 complement factor H isoform b precursor [Homo sapiens]
          Length = 449

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 53/181 (29%), Positives = 83/181 (45%), Gaps = 17/181 (9%)

Query: 163 WSCSGHGECVEIINNYTCNCDVGYYG--PQCQFVIQCEPLEAPELGTM--DCTHPLGNFS 218
           ++C+   + +  IN   C+ D G+    P C+ V++C P+ APE G +      P   + 
Sbjct: 112 YTCNEGYQLLGEINYRECDTD-GWTNDIPICE-VVKCLPVTAPENGKIVSSAMEPDREYH 169

Query: 219 FSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLAS 278
           F     F C+ G  + G EE  C   G WS  +P C  I C+   +PD  ++N S P++ 
Sbjct: 170 FGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCK---SPD--VINGS-PISQ 223

Query: 279 ---FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLF 335
              +       + C+ G E   +   +C  SG W  P P C++       I  GDY+PL 
Sbjct: 224 KIIYKENERFQYKCNMGYEYSERGDAVCTESG-W-RPLPSCEEKSCDNPYIPNGDYSPLR 281

Query: 336 I 336
           I
Sbjct: 282 I 282


>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
          Length = 1231

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 53/181 (29%), Positives = 83/181 (45%), Gaps = 17/181 (9%)

Query: 163 WSCSGHGECVEIINNYTCNCDVGYYG--PQCQFVIQCEPLEAPELGTM--DCTHPLGNFS 218
           ++C+   + +  IN   C+ D G+    P C+ V++C P+ APE G +      P   + 
Sbjct: 112 YTCNEGYQLLGEINYRECDTD-GWTNDIPICE-VVKCLPVTAPENGKIVSSAMEPDREYH 169

Query: 219 FSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLAS 278
           F     F C+ G  + G EE  C   G WS  +P C  I C+   +PD  ++N S P++ 
Sbjct: 170 FGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCK---SPD--VINGS-PISQ 223

Query: 279 ---FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLF 335
              +       + C+ G E   +   +C  SG W  P P C++       I  GDY+PL 
Sbjct: 224 KIIYKENERFQYKCNMGYEYSERGDAVCTESG-W-RPLPSCEEKSCDNPYIPNGDYSPLR 281

Query: 336 I 336
           I
Sbjct: 282 I 282



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 38/133 (28%), Positives = 62/133 (46%), Gaps = 7/133 (5%)

Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLG-NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNW 247
           P C   I C      E GT++ +     +++  ++ +++C  G  ++   ETTC   G W
Sbjct: 862 PLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTC-YMGKW 920

Query: 248 SSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG 307
           SSP P C+ + C+  S P++     +H   S+ +    T+ C EG  + G     C    
Sbjct: 921 SSP-PQCEGLPCK--SPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEK 977

Query: 308 IWSNPSPICQKLD 320
            WS+P P C K D
Sbjct: 978 -WSHP-PSCIKTD 988



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 7/105 (6%)

Query: 214  LGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQ--VIQCEPLSAPDLGIMN 271
            +  +    +  + C     + G EE  C   GNW+ P P C+    +C P    D G + 
Sbjct: 1064 MSKYPSGERVRYQCRSPYEMFGDEEVMCLN-GNWTEP-PQCKDSTGKCGPPPPIDNGDIT 1121

Query: 272  CSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
             S PL+ ++  S+  + C    +L G K+  C  +G WS P P C
Sbjct: 1122 -SFPLSVYAPASSVEYQCQNLYQLEGNKRITCR-NGQWSEP-PKC 1163


>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
          Length = 3667

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 46/184 (25%), Positives = 69/184 (37%), Gaps = 30/184 (16%)

Query: 159  SCQPWSC-----------SGHGECVEIINNYTCNCDVGYYGP---QCQF----------- 193
            SC P SC           SG+G     +  ++CN      GP   QCQ            
Sbjct: 2829 SCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMC 2888

Query: 194  -VIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEP 252
             V+ C     P     +     GNF++ +   + C+ G  L G     C P G W  P P
Sbjct: 2889 KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLP 2948

Query: 253  TCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNP 312
             C +I C     P   +++       ++F S   + C+    L+G+    C+ +G WS  
Sbjct: 2949 ECIMIDCGHPGVPPNAVLSGE----KYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGS 3004

Query: 313  SPIC 316
             P C
Sbjct: 3005 QPHC 3008



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 35/129 (27%), Positives = 53/129 (41%), Gaps = 9/129 (6%)

Query: 201  EAPELGTMDCTHP--------LGN-FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPE 251
            + P    + C HP         GN F+F+    FSC+ G  + G  +  C     WS P 
Sbjct: 2826 QLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP 2885

Query: 252  PTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSN 311
            P C+V+ C     P            +F++ +   + C+ G  L G    IC+ +G W  
Sbjct: 2886 PMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDK 2945

Query: 312  PSPICQKLD 320
            P P C  +D
Sbjct: 2946 PLPECIMID 2954



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 4/107 (3%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            N+ +     + C+ G  L G     C    NWS   P+C  + C    +P  G  + +  
Sbjct: 2792 NYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN-- 2849

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKS 322
               F+F    TF C+ G  + G  K  C+++  WS+P P+C+ ++ S
Sbjct: 2850 --GFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCS 2894



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 3/101 (2%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            NF   S   ++C  G  L G EE TC   G+W+  +P C+ +QC     P          
Sbjct: 3031 NFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQC---GNPGTTANGKVFR 3087

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
            +   +F+S+  + C EG  L G     C ++G WS   P C
Sbjct: 3088 IDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 3128



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 6/103 (5%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS--SPEPTCQVIQCEPLSAPDLGIMNCS 273
            ++ + ++  FSC  G +  G     C P G WS  +  P CQ+I C  L  P  G    +
Sbjct: 2674 HYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNG----N 2729

Query: 274  HPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
                  S+ S   F C  G  L+G     C SSG+WS     C
Sbjct: 2730 KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2772



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 45/169 (26%), Positives = 59/169 (34%), Gaps = 29/169 (17%)

Query: 168  HGECVEIINNYTCNCDVGYYG--------------------PQCQFVIQCEPLEAPELGT 207
            +G   E       +CD GY+G                    P CQ +I C  L  P  G 
Sbjct: 2671 NGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQ-IISCGELPTPPNGN 2729

Query: 208  MDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDL 267
               T      S+ S   F+C  G  L G     C   G WS  E  C    C     P+L
Sbjct: 2730 KIGTQT----SYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHC---GIPEL 2782

Query: 268  GIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
             I+N      ++ +     + C+ G  LIG    IC+    WS   P C
Sbjct: 2783 -IVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSC 2830



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 50/200 (25%), Positives = 73/200 (36%), Gaps = 31/200 (15%)

Query: 140  GKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCN------CDVGY--YGPQC 191
            G W+    H    A   T +C      GHG   E  +N+         CD GY  +G + 
Sbjct: 2999 GHWSGSQPHCSGDA---TGTCGDPGTPGHGSRQE--SNFRTKSTVRYACDTGYILHGSEE 3053

Query: 192  QFVIQCEPLEA--PELGTMDCTHP----------LGNFSFSSQCAFSCSEGTNLTGIEET 239
            +  +         PE   + C +P          +   +FSS   +SC EG  L+G    
Sbjct: 3054 RTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVR 3113

Query: 240  TCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEG--TELIG 297
             C   G WS   P C +I C     P  G+         +      +++C  G   EL G
Sbjct: 3114 QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGD----DYVVGQNVSYMCQPGYTMELNG 3169

Query: 298  KKKTICESSGIWSNPSPICQ 317
             +   C  +G WS   P C+
Sbjct: 3170 SRIRTCTINGTWSGVMPTCR 3189



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 4/101 (3%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            NF +    ++ CS G  L+     TC   G WS   P C    C     P  G       
Sbjct: 3208 NFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG----KRE 3263

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
              SF + S  +F C+    L+G    IC++ G WS  SP C
Sbjct: 3264 GKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3304



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 10/98 (10%)

Query: 220  SSQCAFSCSEGTNLTGIEETTCGP----FGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            +S   ++C  G  L G     C      +  W +P P CQ I C    AP  G +  +  
Sbjct: 2549 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDY 2608

Query: 276  LASFSFTSACTFICSEGTELIGKKKT--ICESSGIWSN 311
            L      +  T+ C++G  L  K+ T  +C+S G WSN
Sbjct: 2609 LVG----TRVTYFCNDGYRLSSKELTTAVCQSDGTWSN 2642



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 39/145 (26%), Positives = 54/145 (37%), Gaps = 15/145 (10%)

Query: 180  CNCDVGYYG--PQCQFVIQ--CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTG 235
            C  D  + G  P C    Q  CE    P  G+ + T     F   S   F C +G  L G
Sbjct: 3291 CQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTF---GFQVGSVVQFHCKKGHLLQG 3347

Query: 236  IEETTCGPFGNWSSPEPTCQVIQC-EPLSAPDLGIMNCSHPLASFSFTSACT--FICSEG 292
                TC P   WS  +P C    C +P +     ++    P   ++    C   F  + G
Sbjct: 3348 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3407

Query: 293  TELIGKKKTICESSGIWSNPSPICQ 317
            TE       +C S   W+   PIC+
Sbjct: 3408 TE-----HRVCRSDNTWTGKVPICE 3427



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 224  AFSCSEG--TNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSF 281
            ++ C  G    L G    TC   G WS   PTC+ + C   + P   I N      +F +
Sbjct: 3156 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCP--TPPQ--ISNGRLEGTNFDW 3211

Query: 282  TSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
              + ++ICS G EL       C  +G WS   P C
Sbjct: 3212 GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3246



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 9/77 (11%)

Query: 197  CEPLEAPELGTMDCTHPLG-NFSFSSQCAFSCSEGTNLTGIEETTCGPFGN--WSSPEPT 253
            CE    P+ G+      +G NF       FSCS G  L G  E  C   G   WS+P P 
Sbjct: 1142 CEDPGIPQYGSR-----IGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPR 1196

Query: 254  CQVIQCEPLSAPDLGIM 270
            C V +C   +  + GI+
Sbjct: 1197 C-VAECGASATNNEGIL 1212



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 16/38 (42%), Positives = 20/38 (52%)

Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
           FS      F C  G ELIG+K  +C+ +  WS   PIC
Sbjct: 640 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 677



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 19/60 (31%), Positives = 27/60 (45%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            +FS  S  +FSC  G  L+  E   C     WS P PTC  +    +  P   I++  +P
Sbjct: 985  DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYP 1044



 Score = 35.4 bits (80), Expect = 0.083
 Identities = 15/41 (36%), Positives = 21/41 (51%)

Query: 279  FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
            FS  S  +F C  G  L  ++  +CE +  WS+P P C  L
Sbjct: 986  FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL 1026



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 4/48 (8%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC----GPFGNWSSPEPTCQVIQC 259
           +FS  S   FSC E   L G +  TC      F  WS   P C+V  C
Sbjct: 461 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 508



 Score = 33.1 bits (74), Expect = 0.41
 Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 6/60 (10%)

Query: 259  CEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG--IWSNPSPIC 316
            CE    P  G    S    +F      TF CS G  L G  + IC   G  +WS P P C
Sbjct: 1142 CEDPGIPQYG----SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1197



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 3/38 (7%)

Query: 224  AFSCSEGTNLTGIEETTC--GPFGNWSSPEPTCQVIQC 259
            +F C +G +L G    TC  GP   W+ P P C + QC
Sbjct: 2035 SFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQC 2071


>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
            sapiens]
          Length = 3538

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 46/184 (25%), Positives = 69/184 (37%), Gaps = 30/184 (16%)

Query: 159  SCQPWSC-----------SGHGECVEIINNYTCNCDVGYYGP---QCQF----------- 193
            SC P SC           SG+G     +  ++CN      GP   QCQ            
Sbjct: 2700 SCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMC 2759

Query: 194  -VIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEP 252
             V+ C     P     +     GNF++ +   + C+ G  L G     C P G W  P P
Sbjct: 2760 KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLP 2819

Query: 253  TCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNP 312
             C +I C     P   +++       ++F S   + C+    L+G+    C+ +G WS  
Sbjct: 2820 ECIMIDCGHPGVPPNAVLSGE----KYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGS 2875

Query: 313  SPIC 316
             P C
Sbjct: 2876 QPHC 2879



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 35/129 (27%), Positives = 53/129 (41%), Gaps = 9/129 (6%)

Query: 201  EAPELGTMDCTHP--------LGN-FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPE 251
            + P    + C HP         GN F+F+    FSC+ G  + G  +  C     WS P 
Sbjct: 2697 QLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP 2756

Query: 252  PTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSN 311
            P C+V+ C     P            +F++ +   + C+ G  L G    IC+ +G W  
Sbjct: 2757 PMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDK 2816

Query: 312  PSPICQKLD 320
            P P C  +D
Sbjct: 2817 PLPECIMID 2825



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 4/107 (3%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            N+ +     + C+ G  L G     C    NWS   P+C  + C    +P  G  + +  
Sbjct: 2663 NYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN-- 2720

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKS 322
               F+F    TF C+ G  + G  K  C+++  WS+P P+C+ ++ S
Sbjct: 2721 --GFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCS 2765



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 3/101 (2%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            NF   S   ++C  G  L G EE TC   G+W+  +P C+ +QC     P          
Sbjct: 2902 NFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQC---GNPGTTANGKVFR 2958

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
            +   +F+S+  + C EG  L G     C ++G WS   P C
Sbjct: 2959 IDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 2999



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 46/163 (28%), Positives = 64/163 (39%), Gaps = 18/163 (11%)

Query: 163  WSCSGHGECVEIINNYTCNCDVGYYG-----PQCQFVIQCEPLEAPELGTMDCTHPLGNF 217
            W+C      V   +        GY+      P CQ  I C   +AP  G +  T    ++
Sbjct: 2490 WACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ-AISCGIPKAPTNGGILTT----DY 2544

Query: 218  SFSSQCAFSCSEGTNLTGIEETT--CGPFGNWSSPE--PTCQVIQCEPLSAPDLGIMNCS 273
               ++  + C++G  L+  E TT  C   G WS+    P C VI C  L  P  G    +
Sbjct: 2545 LVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNG----N 2600

Query: 274  HPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
                  S+ S   F C  G  L+G     C SSG+WS     C
Sbjct: 2601 KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2643



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 50/200 (25%), Positives = 73/200 (36%), Gaps = 31/200 (15%)

Query: 140  GKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCN------CDVGY--YGPQC 191
            G W+    H    A   T +C      GHG   E  +N+         CD GY  +G + 
Sbjct: 2870 GHWSGSQPHCSGDA---TGTCGDPGTPGHGSRQE--SNFRTKSTVRYACDTGYILHGSEE 2924

Query: 192  QFVIQCEPLEA--PELGTMDCTHP----------LGNFSFSSQCAFSCSEGTNLTGIEET 239
            +  +         PE   + C +P          +   +FSS   +SC EG  L+G    
Sbjct: 2925 RTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVR 2984

Query: 240  TCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEG--TELIG 297
             C   G WS   P C +I C     P  G+         +      +++C  G   EL G
Sbjct: 2985 QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGD----DYVVGQNVSYMCQPGYTMELNG 3040

Query: 298  KKKTICESSGIWSNPSPICQ 317
             +   C  +G WS   P C+
Sbjct: 3041 SRIRTCTINGTWSGVMPTCR 3060



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 4/101 (3%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            NF +    ++ CS G  L+     TC   G WS   P C    C     P  G       
Sbjct: 3079 NFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG----KRE 3134

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
              SF + S  +F C+    L+G    IC++ G WS  SP C
Sbjct: 3135 GKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3175



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 38/128 (29%), Positives = 49/128 (38%), Gaps = 9/128 (7%)

Query: 189  PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS 248
            P+C  VI C  L  P  G    T      S+ S   F+C  G  L G     C   G WS
Sbjct: 2583 PRC-VVISCGELPTPPNGNKIGTQT----SYGSTAIFTCDLGFMLVGSAVRECLSSGLWS 2637

Query: 249  SPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGI 308
              E  C    C     P+L I+N      ++ +     + C+ G  LIG    IC+    
Sbjct: 2638 ESETRCLAGHC---GIPEL-IVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHN 2693

Query: 309  WSNPSPIC 316
            WS   P C
Sbjct: 2694 WSGQLPSC 2701



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 39/145 (26%), Positives = 54/145 (37%), Gaps = 15/145 (10%)

Query: 180  CNCDVGYYG--PQCQFVIQ--CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTG 235
            C  D  + G  P C    Q  CE    P  G+ + T     F   S   F C +G  L G
Sbjct: 3162 CQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTF---GFQVGSVVQFHCKKGHLLQG 3218

Query: 236  IEETTCGPFGNWSSPEPTCQVIQC-EPLSAPDLGIMNCSHPLASFSFTSACT--FICSEG 292
                TC P   WS  +P C    C +P +     ++    P   ++    C   F  + G
Sbjct: 3219 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3278

Query: 293  TELIGKKKTICESSGIWSNPSPICQ 317
            TE       +C S   W+   PIC+
Sbjct: 3279 TE-----HRVCRSDNTWTGKVPICE 3298



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 224  AFSCSEG--TNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSF 281
            ++ C  G    L G    TC   G WS   PTC+ + C   + P   I N      +F +
Sbjct: 3027 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCP--TPPQ--ISNGRLEGTNFDW 3082

Query: 282  TSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
              + ++ICS G EL       C  +G WS   P C
Sbjct: 3083 GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3117



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 9/77 (11%)

Query: 197  CEPLEAPELGTMDCTHPLG-NFSFSSQCAFSCSEGTNLTGIEETTCGPFGN--WSSPEPT 253
            CE    P+ G+      +G NF       FSCS G  L G  E  C   G   WS+P P 
Sbjct: 1078 CEDPGIPQYGSR-----IGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPR 1132

Query: 254  CQVIQCEPLSAPDLGIM 270
            C V +C   +  + GI+
Sbjct: 1133 C-VAECGASATNNEGIL 1148



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 16/38 (42%), Positives = 20/38 (52%)

Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
           FS      F C  G ELIG+K  +C+ +  WS   PIC
Sbjct: 576 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 613



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 19/60 (31%), Positives = 27/60 (45%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
           +FS  S  +FSC  G  L+  E   C     WS P PTC  +    +  P   I++  +P
Sbjct: 921 DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYP 980



 Score = 35.4 bits (80), Expect = 0.083
 Identities = 15/41 (36%), Positives = 21/41 (51%)

Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
           FS  S  +F C  G  L  ++  +CE +  WS+P P C  L
Sbjct: 922 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL 962



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 4/48 (8%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC----GPFGNWSSPEPTCQVIQC 259
           +FS  S   FSC E   L G +  TC      F  WS   P C+V  C
Sbjct: 397 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444



 Score = 33.1 bits (74), Expect = 0.41
 Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 6/60 (10%)

Query: 259  CEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG--IWSNPSPIC 316
            CE    P  G    S    +F      TF CS G  L G  + IC   G  +WS P P C
Sbjct: 1078 CEDPGIPQYG----SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1133



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 3/38 (7%)

Query: 224  AFSCSEGTNLTGIEETTC--GPFGNWSSPEPTCQVIQC 259
            +F C +G +L G    TC  GP   W+ P P C + QC
Sbjct: 1971 SFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQC 2007



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 13/41 (31%), Positives = 17/41 (41%), Gaps = 4/41 (9%)

Query: 283  SACTFICSEGTELIGKKKTICESSG----IWSNPSPICQKL 319
            S   + C  G  L+GK   +C  S      W  P P CQ +
Sbjct: 2486 SVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI 2526


>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
          Length = 3707

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 46/184 (25%), Positives = 69/184 (37%), Gaps = 30/184 (16%)

Query: 159  SCQPWSC-----------SGHGECVEIINNYTCNCDVGYYGP---QCQF----------- 193
            SC P SC           SG+G     +  ++CN      GP   QCQ            
Sbjct: 2869 SCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMC 2928

Query: 194  -VIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEP 252
             V+ C     P     +     GNF++ +   + C+ G  L G     C P G W  P P
Sbjct: 2929 KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLP 2988

Query: 253  TCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNP 312
             C +I C     P   +++       ++F S   + C+    L+G+    C+ +G WS  
Sbjct: 2989 ECIMIDCGHPGVPPNAVLSGE----KYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGS 3044

Query: 313  SPIC 316
             P C
Sbjct: 3045 QPHC 3048



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 35/129 (27%), Positives = 53/129 (41%), Gaps = 9/129 (6%)

Query: 201  EAPELGTMDCTHP--------LGN-FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPE 251
            + P    + C HP         GN F+F+    FSC+ G  + G  +  C     WS P 
Sbjct: 2866 QLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP 2925

Query: 252  PTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSN 311
            P C+V+ C     P            +F++ +   + C+ G  L G    IC+ +G W  
Sbjct: 2926 PMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDK 2985

Query: 312  PSPICQKLD 320
            P P C  +D
Sbjct: 2986 PLPECIMID 2994



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 4/107 (3%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            N+ +     + C+ G  L G     C    NWS   P+C  + C    +P  G  + +  
Sbjct: 2832 NYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN-- 2889

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKS 322
               F+F    TF C+ G  + G  K  C+++  WS+P P+C+ ++ S
Sbjct: 2890 --GFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCS 2934



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 3/101 (2%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            NF   S   ++C  G  L G EE TC   G+W+  +P C+ +QC     P          
Sbjct: 3071 NFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQC---GNPGTTANGKVFR 3127

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
            +   +F+S+  + C EG  L G     C ++G WS   P C
Sbjct: 3128 IDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 3168



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 6/103 (5%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS--SPEPTCQVIQCEPLSAPDLGIMNCS 273
            ++ + ++  FSC  G +  G     C P G WS  +  P CQ+I C  L  P  G    +
Sbjct: 2714 HYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNG----N 2769

Query: 274  HPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
                  S+ S   F C  G  L+G     C SSG+WS     C
Sbjct: 2770 KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2812



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 45/169 (26%), Positives = 59/169 (34%), Gaps = 29/169 (17%)

Query: 168  HGECVEIINNYTCNCDVGYYG--------------------PQCQFVIQCEPLEAPELGT 207
            +G   E       +CD GY+G                    P CQ +I C  L  P  G 
Sbjct: 2711 NGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQ-IISCGELPTPPNGN 2769

Query: 208  MDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDL 267
               T      S+ S   F+C  G  L G     C   G WS  E  C    C     P+L
Sbjct: 2770 KIGTQT----SYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHC---GIPEL 2822

Query: 268  GIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
             I+N      ++ +     + C+ G  LIG    IC+    WS   P C
Sbjct: 2823 -IVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSC 2870



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 50/200 (25%), Positives = 73/200 (36%), Gaps = 31/200 (15%)

Query: 140  GKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCN------CDVGY--YGPQC 191
            G W+    H    A   T +C      GHG   E  +N+         CD GY  +G + 
Sbjct: 3039 GHWSGSQPHCSGDA---TGTCGDPGTPGHGSRQE--SNFRTKSTVRYACDTGYILHGSEE 3093

Query: 192  QFVIQCEPLEA--PELGTMDCTHP----------LGNFSFSSQCAFSCSEGTNLTGIEET 239
            +  +         PE   + C +P          +   +FSS   +SC EG  L+G    
Sbjct: 3094 RTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVR 3153

Query: 240  TCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEG--TELIG 297
             C   G WS   P C +I C     P  G+         +      +++C  G   EL G
Sbjct: 3154 QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGD----DYVVGQNVSYMCQPGYTMELNG 3209

Query: 298  KKKTICESSGIWSNPSPICQ 317
             +   C  +G WS   P C+
Sbjct: 3210 SRIRTCTINGTWSGVMPTCR 3229



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 4/101 (3%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            NF +    ++ CS G  L+     TC   G WS   P C    C     P  G       
Sbjct: 3248 NFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG----KRE 3303

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
              SF + S  +F C+    L+G    IC++ G WS  SP C
Sbjct: 3304 GKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3344



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 10/98 (10%)

Query: 220  SSQCAFSCSEGTNLTGIEETTCGP----FGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            +S   ++C  G  L G     C      +  W +P P CQ I C    AP  G +  +  
Sbjct: 2589 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDY 2648

Query: 276  LASFSFTSACTFICSEGTELIGKKKT--ICESSGIWSN 311
            L      +  T+ C++G  L  K+ T  +C+S G WSN
Sbjct: 2649 LVG----TRVTYFCNDGYRLSSKELTTAVCQSDGTWSN 2682



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 39/145 (26%), Positives = 54/145 (37%), Gaps = 15/145 (10%)

Query: 180  CNCDVGYYG--PQCQFVIQ--CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTG 235
            C  D  + G  P C    Q  CE    P  G+ + T     F   S   F C +G  L G
Sbjct: 3331 CQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTF---GFQVGSVVQFHCKKGHLLQG 3387

Query: 236  IEETTCGPFGNWSSPEPTCQVIQC-EPLSAPDLGIMNCSHPLASFSFTSACT--FICSEG 292
                TC P   WS  +P C    C +P +     ++    P   ++    C   F  + G
Sbjct: 3388 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3447

Query: 293  TELIGKKKTICESSGIWSNPSPICQ 317
            TE       +C S   W+   PIC+
Sbjct: 3448 TE-----HRVCRSDNTWTGKVPICE 3467



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 224  AFSCSEG--TNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSF 281
            ++ C  G    L G    TC   G WS   PTC+ + C   + P   I N      +F +
Sbjct: 3196 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCP--TPPQ--ISNGRLEGTNFDW 3251

Query: 282  TSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
              + ++ICS G EL       C  +G WS   P C
Sbjct: 3252 GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3286



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 9/77 (11%)

Query: 197  CEPLEAPELGTMDCTHPLG-NFSFSSQCAFSCSEGTNLTGIEETTCGPFGN--WSSPEPT 253
            CE    P+ G+      +G NF       FSCS G  L G  E  C   G   WS+P P 
Sbjct: 1182 CEDPGIPQYGSR-----IGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPR 1236

Query: 254  CQVIQCEPLSAPDLGIM 270
            C V +C   +  + GI+
Sbjct: 1237 C-VAECGASATNNEGIL 1252



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 16/38 (42%), Positives = 20/38 (52%)

Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
           FS      F C  G ELIG+K  +C+ +  WS   PIC
Sbjct: 680 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 717



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 19/60 (31%), Positives = 27/60 (45%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            +FS  S  +FSC  G  L+  E   C     WS P PTC  +    +  P   I++  +P
Sbjct: 1025 DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYP 1084



 Score = 35.4 bits (80), Expect = 0.083
 Identities = 15/41 (36%), Positives = 21/41 (51%)

Query: 279  FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
            FS  S  +F C  G  L  ++  +CE +  WS+P P C  L
Sbjct: 1026 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL 1066



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 4/48 (8%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC----GPFGNWSSPEPTCQVIQC 259
           +FS  S   FSC E   L G +  TC      F  WS   P C+V  C
Sbjct: 501 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 548



 Score = 33.1 bits (74), Expect = 0.41
 Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 6/60 (10%)

Query: 259  CEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG--IWSNPSPIC 316
            CE    P  G    S    +F      TF CS G  L G  + IC   G  +WS P P C
Sbjct: 1182 CEDPGIPQYG----SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1237



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 3/38 (7%)

Query: 224  AFSCSEGTNLTGIEETTC--GPFGNWSSPEPTCQVIQC 259
            +F C +G +L G    TC  GP   W+ P P C + QC
Sbjct: 2075 SFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQC 2111


>gi|223029384 CD209 molecule isoform 7 [Homo sapiens]
          Length = 312

 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 45/157 (28%), Positives = 64/157 (40%), Gaps = 17/157 (10%)

Query: 14  LWNIFKLWGWTMLCCDFLAHHGTDCWT------YHYSEKPMNWQRARRFCRDNYTDLVAI 67
           L  I++   W     + L H     WT      Y  S    NW  +   C++    LV I
Sbjct: 143 LQEIYQELTWLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVI 202

Query: 68  QNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIWTWVGTNKSLTEEAENWGDGEPNNKKNK 125
           ++  E  +L+     S  + W+G+  +   G W WV  +  L    + W  GEPNN   +
Sbjct: 203 KSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNN-VGE 261

Query: 126 EDCVEIYIKRNKDAGKWNDDACHKLKAALC--YTASC 160
           EDC E           WNDD C+  K  +C    ASC
Sbjct: 262 EDCAEF------SGNGWNDDKCNLAKFWICKKSAASC 292


>gi|223029380 CD209 molecule isoform 5 [Homo sapiens]
          Length = 268

 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 45/157 (28%), Positives = 64/157 (40%), Gaps = 17/157 (10%)

Query: 14  LWNIFKLWGWTMLCCDFLAHHGTDCWT------YHYSEKPMNWQRARRFCRDNYTDLVAI 67
           L  I++   W     + L H     WT      Y  S    NW  +   C++    LV I
Sbjct: 99  LQEIYQELTWLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVI 158

Query: 68  QNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIWTWVGTNKSLTEEAENWGDGEPNNKKNK 125
           ++  E  +L+     S  + W+G+  +   G W WV  +  L    + W  GEPNN   +
Sbjct: 159 KSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNN-VGE 217

Query: 126 EDCVEIYIKRNKDAGKWNDDACHKLKAALC--YTASC 160
           EDC E           WNDD C+  K  +C    ASC
Sbjct: 218 EDCAEF------SGNGWNDDKCNLAKFWICKKSAASC 248


>gi|4505245 mannose receptor C type 1 precursor [Homo sapiens]
          Length = 1456

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 6/120 (5%)

Query: 45   EKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTN 104
            E+  NWQ AR+ C     +LV+IQN+ E  +L   +  S    W G+  +    T++ T+
Sbjct: 965  EERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTD 1024

Query: 105  KSLTEEAENWGDGEPNNKKNK-----EDCVEIYIKRNKDAGKWNDDACHKLKAALCYTAS 159
                    NWG G P  +++       DCV I    + +AGKW DD C   +  +C T S
Sbjct: 1025 -GRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRS 1083



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 44/154 (28%), Positives = 75/154 (48%), Gaps = 17/154 (11%)

Query: 39  WTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTL--PFSRSYYWIGIR-KIG 95
           + Y++S++      AR FC+ N+ DLV+IQ+++E ++L K +    ++S Y+IG+   + 
Sbjct: 810 YQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLISLD 869

Query: 96  GIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
             + W+  +K    +  +W  GEPN     E+CV +Y     ++G WND  C    A +C
Sbjct: 870 KKFAWMDGSK---VDYVSWATGEPNFANEDENCVTMY----SNSGFWNDINCGYPNAFIC 922

Query: 156 Y-------TASCQPWSCSGHGECVEIINNYTCNC 182
                     +  P   S    C E  N Y+  C
Sbjct: 923 QRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKC 956



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 36/111 (32%), Positives = 51/111 (45%), Gaps = 11/111 (9%)

Query: 50  WQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSY---YWIGIR--KIGGIWTWVGTN 104
           W  +R FCR    DL +I NK E + + + +  S SY   +W+G+        +TW   +
Sbjct: 673 WFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTW---S 729

Query: 105 KSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
                  ENW  GEPNN +N E C E+   +      WND  C  L   +C
Sbjct: 730 DGSPVSYENWAYGEPNNYQNVEYCGEL---KGDPTMSWNDINCEHLNNWIC 777



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 37/129 (28%), Positives = 64/129 (49%), Gaps = 14/129 (10%)

Query: 30   FLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLE-KTLPF-SRSYY 87
            ++  HG  C+ Y  S    NW +A   C    + LV+I++ AE  +L  +  P  S++ +
Sbjct: 1238 WIPFHG-HCY-YIESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNF 1295

Query: 88   WIGI-RKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDA 146
            WIG+ R + G W W+  +        NW  G+P+ ++N  DCV ++      +G W++  
Sbjct: 1296 WIGLFRNVEGTWLWINNSPV---SFVNWNTGDPSGERN--DCVALH----ASSGFWSNIH 1346

Query: 147  CHKLKAALC 155
            C   K  +C
Sbjct: 1347 CSSYKGYIC 1355



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 5/112 (4%)

Query: 44  SEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGT 103
           S+  + W +AR+ C+    +L++I    E  YL        S  WIG+  +     W  +
Sbjct: 234 SKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWS 293

Query: 104 NKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
           ++S      NW  G P+ +  K  CV +   +N    KW +  C +    +C
Sbjct: 294 DRSPFRYL-NWLPGSPSAEPGK-SCVSLNPGKN---AKWENLECVQKLGYIC 340



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 28/130 (21%)

Query: 38  CWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGI 97
           C+  H  EK +  + A   CR    DL +I    E++++   L +  +            
Sbjct: 373 CYKIHRDEKKIQ-RDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDE---------- 421

Query: 98  WTWVGTNKSLTEEAENWGD-----------GEPNNKKNK-EDCVEIYIKRNKDAGKWNDD 145
             W+G N    +    W D           GEP+++ N+ EDCV   + + KD G W D 
Sbjct: 422 -LWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCV---VMKGKD-GYWADR 476

Query: 146 ACHKLKAALC 155
            C      +C
Sbjct: 477 GCEWPLGYIC 486



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 32/167 (19%), Positives = 60/167 (35%), Gaps = 42/167 (25%)

Query: 40   TYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWT 99
            +Y    +   W  A  +C+ + + + +I +           P+S ++ W+ + +      
Sbjct: 1106 SYSLMRQKFQWHEAETYCKLHNSLIASILD-----------PYSNAFAWLQM-ETSNERV 1153

Query: 100  WVGTNKSLTEEAENWGD--------GEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLK 151
            W+  N +LT+    W D           +  K K  CV + +      G W    C++  
Sbjct: 1154 WIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLD-----GYWKTAHCNESF 1208

Query: 152  AALCYTA----SCQPWSCSG-------------HGECVEIINNYTCN 181
              LC  +    + +P    G             HG C  I ++YT N
Sbjct: 1209 YFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRN 1255


>gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens]
          Length = 1456

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 6/120 (5%)

Query: 45   EKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTN 104
            E+  NWQ AR+ C     +LV+IQN+ E  +L   +  S    W G+  +    T++ T+
Sbjct: 965  EERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTD 1024

Query: 105  KSLTEEAENWGDGEPNNKKNK-----EDCVEIYIKRNKDAGKWNDDACHKLKAALCYTAS 159
                    NWG G P  +++       DCV I    + +AGKW DD C   +  +C T S
Sbjct: 1025 -GRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRS 1083



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 44/154 (28%), Positives = 75/154 (48%), Gaps = 17/154 (11%)

Query: 39  WTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTL--PFSRSYYWIGIR-KIG 95
           + Y++S++      AR FC+ N+ DLV+IQ+++E ++L K +    ++S Y+IG+   + 
Sbjct: 810 YQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLISLD 869

Query: 96  GIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
             + W+  +K    +  +W  GEPN     E+CV +Y     ++G WND  C    A +C
Sbjct: 870 KKFAWMDGSK---VDYVSWATGEPNFANEDENCVTMY----SNSGFWNDINCGYPNAFIC 922

Query: 156 Y-------TASCQPWSCSGHGECVEIINNYTCNC 182
                     +  P   S    C E  N Y+  C
Sbjct: 923 QRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKC 956



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 36/111 (32%), Positives = 51/111 (45%), Gaps = 11/111 (9%)

Query: 50  WQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSY---YWIGIR--KIGGIWTWVGTN 104
           W  +R FCR    DL +I NK E + + + +  S SY   +W+G+        +TW   +
Sbjct: 673 WFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTW---S 729

Query: 105 KSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
                  ENW  GEPNN +N E C E+   +      WND  C  L   +C
Sbjct: 730 DGSPVSYENWAYGEPNNYQNVEYCGEL---KGDPTMSWNDINCEHLNNWIC 777



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 37/129 (28%), Positives = 64/129 (49%), Gaps = 14/129 (10%)

Query: 30   FLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLE-KTLPF-SRSYY 87
            ++  HG  C+ Y  S    NW +A   C    + LV+I++ AE  +L  +  P  S++ +
Sbjct: 1238 WIPFHG-HCY-YIESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNF 1295

Query: 88   WIGI-RKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDA 146
            WIG+ R + G W W+  +        NW  G+P+ ++N  DCV ++      +G W++  
Sbjct: 1296 WIGLFRNVEGTWLWINNSPV---SFVNWNTGDPSGERN--DCVALH----ASSGFWSNIH 1346

Query: 147  CHKLKAALC 155
            C   K  +C
Sbjct: 1347 CSSYKGYIC 1355



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 5/112 (4%)

Query: 44  SEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGT 103
           S+  + W +AR+ C+    +L++I    E  YL        S  WIG+  +     W  +
Sbjct: 234 SKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWS 293

Query: 104 NKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
           ++S      NW  G P+ +  K  CV +   +N    KW +  C +    +C
Sbjct: 294 DRSPFRYL-NWLPGSPSAEPGK-SCVSLNPGKN---AKWENLECVQKLGYIC 340



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 28/130 (21%)

Query: 38  CWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGI 97
           C+  H  EK +  + A   CR   +DL +I    E +++   L +  +            
Sbjct: 373 CYKIHRDEKKIQ-RDALTTCRKEGSDLASIHTIEEFDFIISQLGYEPNDE---------- 421

Query: 98  WTWVGTNKSLTEEAENWGD-----------GEPNNKKNK-EDCVEIYIKRNKDAGKWNDD 145
             W+G N    +    W D           GEP+++ N+ EDCV   + + KD G W D 
Sbjct: 422 -LWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCV---VMKGKD-GYWADR 476

Query: 146 ACHKLKAALC 155
            C      +C
Sbjct: 477 GCEWPLGYIC 486



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 32/167 (19%), Positives = 60/167 (35%), Gaps = 42/167 (25%)

Query: 40   TYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWT 99
            +Y    +   W  A  +C+ + + + +I +           P+S ++ W+ + +      
Sbjct: 1106 SYSLMRQKFQWHEAETYCKLHNSLIASILD-----------PYSNAFAWLQM-ETSNERV 1153

Query: 100  WVGTNKSLTEEAENWGD--------GEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLK 151
            W+  N +LT+    W D           +  K K  CV + +      G W    C++  
Sbjct: 1154 WIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLD-----GYWKTAHCNESF 1208

Query: 152  AALCYTA----SCQPWSCSG-------------HGECVEIINNYTCN 181
              LC  +    + +P    G             HG C  I ++YT N
Sbjct: 1209 YFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRN 1255


>gi|20149533 Fc fragment of IgE, low affinity II, receptor for
           (CD23A) [Homo sapiens]
          Length = 321

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 14/134 (10%)

Query: 41  YHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIW 98
           Y++ +    W  AR  C D    LV+I +  E ++L K    + S  WIG+R +   G +
Sbjct: 175 YYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGS--WIGLRNLDLKGEF 232

Query: 99  TWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDAC-HKLKAALC-Y 156
            WV  +     +  NW  GEP ++   EDCV +     + +G+WND  C  KL A +C  
Sbjct: 233 IWVDGSH---VDYSNWAPGEPTSRSQGEDCVMM-----RGSGRWNDAFCDRKLGAWVCDR 284

Query: 157 TASCQPWSCSGHGE 170
            A+C P +  G  E
Sbjct: 285 LATCTPPASEGSAE 298


>gi|223029517 CD209 molecule isoform 8 [Homo sapiens]
          Length = 243

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 11/124 (8%)

Query: 41  YHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIW 98
           Y  S    NW  +   C++    LV I++  E  +L+     S  + W+G+  +   G W
Sbjct: 107 YFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTW 166

Query: 99  TWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC--Y 156
            WV  +  L    + W  GEPNN   +EDC E           WNDD C+  K  +C   
Sbjct: 167 QWVDGSPLLPSFKQYWNRGEPNN-VGEEDCAEF------SGNGWNDDKCNLAKFWICKKS 219

Query: 157 TASC 160
            ASC
Sbjct: 220 AASC 223


>gi|223029386 CD209 molecule isoform 3 [Homo sapiens]
          Length = 380

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 11/124 (8%)

Query: 41  YHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIW 98
           Y  S    NW  +   C++    LV I++  E  +L+     S  + W+G+  +   G W
Sbjct: 244 YFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTW 303

Query: 99  TWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC--Y 156
            WV  +  L    + W  GEPNN   +EDC E           WNDD C+  K  +C   
Sbjct: 304 QWVDGSPLLPSFKQYWNRGEPNN-VGEEDCAEF------SGNGWNDDKCNLAKFWICKKS 356

Query: 157 TASC 160
            ASC
Sbjct: 357 AASC 360


>gi|223029382 CD209 molecule isoform 6 [Homo sapiens]
          Length = 360

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 11/124 (8%)

Query: 41  YHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIW 98
           Y  S    NW  +   C++    LV I++  E  +L+     S  + W+G+  +   G W
Sbjct: 224 YFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTW 283

Query: 99  TWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC--Y 156
            WV  +  L    + W  GEPNN   +EDC E           WNDD C+  K  +C   
Sbjct: 284 QWVDGSPLLPSFKQYWNRGEPNN-VGEEDCAEF------SGNGWNDDKCNLAKFWICKKS 336

Query: 157 TASC 160
            ASC
Sbjct: 337 AASC 340


>gi|10863957 CD209 molecule isoform 1 [Homo sapiens]
          Length = 404

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 11/124 (8%)

Query: 41  YHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIW 98
           Y  S    NW  +   C++    LV I++  E  +L+     S  + W+G+  +   G W
Sbjct: 268 YFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTW 327

Query: 99  TWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC--Y 156
            WV  +  L    + W  GEPNN   +EDC E           WNDD C+  K  +C   
Sbjct: 328 QWVDGSPLLPSFKQYWNRGEPNN-VGEEDCAEF------SGNGWNDDKCNLAKFWICKKS 380

Query: 157 TASC 160
            ASC
Sbjct: 381 AASC 384


>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
          Length = 3565

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 40/152 (26%), Positives = 61/152 (40%), Gaps = 14/152 (9%)

Query: 178  YTCNCDVGYYGPQCQFVIQCEPL--EAPELGTMDCTHPLGN----------FSFSSQCAF 225
            Y CN      G   +  +Q      + P    + C HP GN          F+ +    F
Sbjct: 2705 YQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHP-GNPAHGFTNGSEFNLNDVVNF 2763

Query: 226  SCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL-ASFSFTSA 284
            +C+ G  L G+    C   G WSSP PTC+V+ C      +  I +       SF +  +
Sbjct: 2764 TCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMS 2823

Query: 285  CTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
              + C +G  L+G     C ++G+W    P C
Sbjct: 2824 ILYHCKKGFYLLGSSALTCMANGLWDRSLPKC 2855



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 3/101 (2%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            +F   S   FSC  G  L G  E TC   G+WS  +P C+ + C     P  G++  S  
Sbjct: 2936 DFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDG 2995

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
            +    F+S+  + C EG +  G     C ++G W+  +P C
Sbjct: 2996 IL---FSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDC 3033



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 32/106 (30%), Positives = 43/106 (40%), Gaps = 4/106 (3%)

Query: 217  FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL 276
            FS+     + C+ G  L G     C     WS   P C  I C     P  G  N S   
Sbjct: 2697 FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSE-- 2754

Query: 277  ASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKS 322
              F+      F C+ G  L G  +  C S+G WS+P P C+ ++ S
Sbjct: 2755 --FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCS 2798



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 38/135 (28%), Positives = 56/135 (41%), Gaps = 11/135 (8%)

Query: 183  DVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFS-FSSQCAFSCSEGTNLTGIEETTC 241
            ++G   P C+ VI C  L  P  G     + +G  + + +   F+C+ G  L G     C
Sbjct: 2610 NIGDERPSCR-VISCGSLSFPPNG-----NKIGTLTVYGATAIFTCNTGYTLVGSHVREC 2663

Query: 242  GPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKT 301
               G WS  E  C    C    +PD  I+N       FS+     + C+ G  L+G    
Sbjct: 2664 LANGLWSGSETRCLAGHC---GSPD-PIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVR 2719

Query: 302  ICESSGIWSNPSPIC 316
            IC     WS  +P+C
Sbjct: 2720 ICLQDHKWSGQTPVC 2734



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 13/152 (8%)

Query: 169  GECVEIINNYTCNCDV-GYYGPQ---CQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCA 224
            G  +E + + T  C   G + P    C+ V+ C      + GT++ +    +F + S  +
Sbjct: 3067 GYVMEAVTSATIRCTKDGRWNPSKPVCKAVL-CPQPPPVQNGTVEGS----DFRWGSSIS 3121

Query: 225  FSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSA 284
            +SC +G  L+     +C   G W    P C  + C     P  G ++      SF++ S 
Sbjct: 3122 YSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGK----SFTYKSE 3177

Query: 285  CTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
              F C     L+G  + +C++ G WS   P C
Sbjct: 3178 VFFQCKSPFILVGSSRRVCQADGTWSGIQPTC 3209



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 36/128 (28%), Positives = 52/128 (40%), Gaps = 12/128 (9%)

Query: 197  CEPLEAPELGTMDCTHPLGNF------SFSSQCAFSCSEGTNLTGIEETTCGPFGNWS-- 248
            C+P+  P +      H +          + +Q   SCS G  L G     C   G W+  
Sbjct: 2553 CKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIG 2612

Query: 249  SPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGI 308
               P+C+VI C  LS P  G  N    L  +  T+   F C+ G  L+G     C ++G+
Sbjct: 2613 DERPSCRVISCGSLSFPPNG--NKIGTLTVYGATA--IFTCNTGYTLVGSHVRECLANGL 2668

Query: 309  WSNPSPIC 316
            WS     C
Sbjct: 2669 WSGSETRC 2676



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 35/123 (28%), Positives = 50/123 (40%), Gaps = 20/123 (16%)

Query: 211  THPLGNFSFSSQCA--------FSCSEGTNLTGIEETTC--GPFG--NWSSPEPTCQVIQ 258
            THPL N    ++ A        + C  G  + G    TC   P G   W S  P CQ + 
Sbjct: 2436 THPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVS 2495

Query: 259  CEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKK--TICESSGIWSNPS--P 314
            C    +P     N S     F+  S   + C EG +L   ++   +C+  G+WSN    P
Sbjct: 2496 CGIPESPG----NGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPP 2551

Query: 315  ICQ 317
             C+
Sbjct: 2552 TCK 2554



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 6/101 (5%)

Query: 219  FSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLAS 278
            FSS   ++C EG   +G+    C   G W+   P C +I C        GI   +     
Sbjct: 2998 FSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGT----D 3053

Query: 279  FSFTSACTFICSEG--TELIGKKKTICESSGIWSNPSPICQ 317
            F+F    ++ C+ G   E +      C   G W+   P+C+
Sbjct: 3054 FTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCK 3094



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 24/101 (23%), Positives = 36/101 (35%), Gaps = 4/101 (3%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            +F +     + C +G  L G    TC   G W    P C  I C     P   ++     
Sbjct: 2817 SFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGE-- 2874

Query: 276  LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
               F++ +   + C     LIG    +C+    WS   P C
Sbjct: 2875 --LFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHC 2913



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 27/104 (25%), Positives = 39/104 (37%), Gaps = 7/104 (6%)

Query: 217  FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQ---CEPLSAPDLGIMNCS 273
            F++ +   +SC    +L G +   C    +WS   P C       C     P  G    S
Sbjct: 2876 FTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHG----S 2931

Query: 274  HPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQ 317
                 F   S   F C  G +L G  +  C  +G WS   P+C+
Sbjct: 2932 RLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCE 2975



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 27/122 (22%), Positives = 45/122 (36%), Gaps = 7/122 (5%)

Query: 197  CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQV 256
            C     P  G  + +     +   S   F C +G ++ G    TC     WS  +  C  
Sbjct: 3217 CPDPGTPHFGIQNSSR---GYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIP 3273

Query: 257  IQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELI-GKKKTICESSGIWSNPSPI 315
              C     P    +  +  L +F +T    + C  G  L  G +   C++   W+  SP+
Sbjct: 3274 HACRQPETPAHADVR-AIDLPTFGYT--LVYTCHPGFFLAGGSEHRTCKADMKWTGKSPV 3330

Query: 316  CQ 317
            C+
Sbjct: 3331 CK 3332



 Score = 32.0 bits (71), Expect = 0.92
 Identities = 13/40 (32%), Positives = 19/40 (47%)

Query: 277 ASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
           +SF      TF C    EL+G++   C+ +  WS   P C
Sbjct: 542 SSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 15/51 (29%), Positives = 21/51 (41%)

Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEG 329
           F   S  TF C  G  L   +  +CE +  W++  P C  L   +   K G
Sbjct: 890 FGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSG 940



 Score = 30.0 bits (66), Expect = 3.5
 Identities = 13/43 (30%), Positives = 18/43 (41%)

Query: 215 GNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVI 257
           G+F   S   FSC  G  L+  E   C     W+   P+C  +
Sbjct: 888 GDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL 930



 Score = 29.6 bits (65), Expect = 4.6
 Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 3/46 (6%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGN--WSSPEPTCQVIQC 259
            +F       FSC  G  L G  + TC   G   WS+P P C V +C
Sbjct: 1061 HFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC-VAEC 1105


>gi|33667103 C-type lectin, superfamily member 14 isoform 1 [Homo
           sapiens]
          Length = 316

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 16/129 (12%)

Query: 27  CCDF-LAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRS 85
           CC      H   C  Y +S   M+W  A ++C+     LV I ++ E  +++K L    +
Sbjct: 180 CCPVNWVEHQDSC--YWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYL--GSA 235

Query: 86  YYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNK-----EDCVEIYIKRNKDAG 140
           Y W+G+    G W WV      T   +NW  G+P++ +       EDC   +       G
Sbjct: 236 YTWMGLSDPEGAWKWVDGTDYAT-GFQNWKPGQPDDWQGHGLGGGEDCAHFH-----PDG 289

Query: 141 KWNDDACHK 149
           +WNDD C +
Sbjct: 290 RWNDDVCQR 298


>gi|53832016 C-type lectin, superfamily member 14 isoform 2 [Homo
           sapiens]
          Length = 292

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 16/129 (12%)

Query: 27  CCDF-LAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRS 85
           CC      H   C  Y +S   M+W  A ++C+     LV I ++ E  +++K L    +
Sbjct: 156 CCPVNWVEHQDSC--YWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYL--GSA 211

Query: 86  YYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNK-----EDCVEIYIKRNKDAG 140
           Y W+G+    G W WV      T   +NW  G+P++ +       EDC   +       G
Sbjct: 212 YTWMGLSDPEGAWKWVDGTDYAT-GFQNWKPGQPDDWQGHGLGGGEDCAHFH-----PDG 265

Query: 141 KWNDDACHK 149
           +WNDD C +
Sbjct: 266 RWNDDVCQR 274


>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
          Length = 2489

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 44/138 (31%), Positives = 59/138 (42%), Gaps = 17/138 (12%)

Query: 197  CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPT 253
            C P   P  G +   H   +  F S   +SC+EG  L G   TTC   GN   W    P 
Sbjct: 1907 CGPPPEPFNGMV---HINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPI 1963

Query: 254  CQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS- 306
            C++I CEP      G    S+   SF   +  T+ C  G       EL+G++   C S  
Sbjct: 1964 CEIISCEPPPTISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKD 2022

Query: 307  ---GIWSNPSPICQKLDK 321
               G+WS+P P C   +K
Sbjct: 2023 DQVGVWSSPPPRCISTNK 2040



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 9/109 (8%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
           NFS   +  +SC  G +L G     C P G+WS   PTC+V  C+      +G +     
Sbjct: 315 NFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF----MGQLLNGRV 370

Query: 276 L--ASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
           L   +    +   F+C EG +L G   + C  +G   +W++  P+C+++
Sbjct: 371 LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 9/109 (8%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
           NFS   +  +SC  G +L G     C P G+WS   PTC+V  C+      +G +     
Sbjct: 765 NFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF----MGQLLNGRV 820

Query: 276 L--ASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
           L   +    +   F+C EG +L G   + C  +G   +W++  P+C+++
Sbjct: 821 LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 869



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 9/109 (8%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
            NFS   +  +SC  G +L G     C P G+WS   PTC+V  C+      +G +     
Sbjct: 1215 NFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF----MGQLLNGRV 1270

Query: 276  L--ASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
            L   +    +   F+C EG +L G   + C  +G   +W++  P+C+++
Sbjct: 1271 LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 1319



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 41/155 (26%), Positives = 71/155 (45%), Gaps = 16/155 (10%)

Query: 174  IINNYTCNCDV-GYYGPQCQFVIQ-CEPLEAPEL--GTMDCTHPLGNFSFSSQCAFSCSE 229
            ++ ++T  C   G +GP+     + C+P   PE+  G    +H   NFS   +  +SC  
Sbjct: 2075 MVGSHTVQCQTNGRWGPKLPHCSRVCQP--PPEILHGEHTLSHQ-DNFSPGQEVFYSCEP 2131

Query: 230  GTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL--ASFSFTSACTF 287
              +L G     C P G+WS   P C V  C+      LG +     L   +    +  +F
Sbjct: 2132 SYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDF----LGQLPHGRVLLPLNLQLGAKVSF 2187

Query: 288  ICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
            +C EG  L G+  + C  +G   +W++  P+C+++
Sbjct: 2188 VCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQI 2222



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 16/138 (11%)

Query: 189  PQCQFVIQCEPLEAPEL--GTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN 246
            P C  V  C+P   PE+  G    +H   NFS   +  +SC  G +L G     C P G+
Sbjct: 1641 PSCSRV--CQP--PPEILHGEHTPSHQ-DNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD 1695

Query: 247  WSSPEPTCQVIQCEPLSAPDLGIMNCSHPL--ASFSFTSACTFICSEGTELIGKKKTICE 304
            WS   P C V  C+      LG +     L   +    +  +F+C EG  L G   + C 
Sbjct: 1696 WSPEAPRCAVKSCDDF----LGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCV 1751

Query: 305  SSG---IWSNPSPICQKL 319
              G   +W+N  P+C+ +
Sbjct: 1752 LVGMRSLWNNSVPVCEHI 1769



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
           H +    F SQ  +SC++G  L G    TC   G+   W +  P C  I C  P +  + 
Sbjct: 116 HVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNG 175

Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
             ++ +    +F + S  T+ C+ G+      EL+G+    C S+    GIWS P+P C
Sbjct: 176 DFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 232



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
           H + +    S+  +SC+ G  L G     C   GN   WS+  P CQ I C  P +  + 
Sbjct: 566 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANG 625

Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
             ++ +    +F + S  T+ C+ G+      EL+G+    C S+    GIWS P+P C
Sbjct: 626 DFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 212  HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
            H + +    S+  +SC+ G  L G     C   GN   WS+  P CQ I C  P +  + 
Sbjct: 1016 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANG 1075

Query: 268  GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
              ++ +    +F + S  T+ C+ G+      EL+G+    C S+    GIWS P+P C
Sbjct: 1076 DFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 1132



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 212  HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
            H + +    S+  +SC+ G  L G     C   GN   WS+  P CQ I C  P +  + 
Sbjct: 1466 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANG 1525

Query: 268  GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
              ++ +    +F + S  T+ C+ G+      EL+G+    C S+    GIWS P+P C
Sbjct: 1526 DFISTNR--ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 1582



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 44/172 (25%), Positives = 66/172 (38%), Gaps = 21/172 (12%)

Query: 163  WSCSGH---GECVEIINNYTCNCDVGYYG--------PQCQFVIQCEPLEAPE-LGTMDC 210
            ++C  H   G    +I   T  C    +G        P+C+  ++    + PE       
Sbjct: 1798 YTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASP 1857

Query: 211  THPLGNFSF--SSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLG 268
            T P+ +F F   +   + C  G     +   +C     WSS E  C+   C P   P  G
Sbjct: 1858 TIPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNG 1916

Query: 269  IMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQ 317
            ++   H      F S   + C+EG  LIG   T C  SG    W   +PIC+
Sbjct: 1917 MV---HINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE 1965



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 16/131 (12%)

Query: 213  PLGNFSFSSQCAFSCSEGT------NLTGIEETTC--GPFGN--WSSPEPTCQVIQCEPL 262
            P G+  +  + +++C          NL G     C   P GN  WSSP P C++    P 
Sbjct: 2239 PFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCEL--SVPA 2296

Query: 263  SAPDLGIMNCSHPLAS----FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQK 318
            + P    +   H +      +      ++IC  G  L+GK    C   GIWS     C++
Sbjct: 2297 ACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKE 2356

Query: 319  LDKSFSMIKEG 329
            ++ SF +   G
Sbjct: 2357 VNCSFPLFMNG 2367



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 35/114 (30%), Positives = 48/114 (42%), Gaps = 14/114 (12%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGNWSSPEPTCQVIQCEPLSAPDLGIMNC 272
            N    ++  F C EG  L G   + C   G    W+S  P C+ I C        G  + 
Sbjct: 1275 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG-RHT 1333

Query: 273  SHPLASFSFTSACTFICS----EGT--ELIGKKKTICES----SGIWSNPSPIC 316
              PL  F F  A  + C      GT  +LIG+    C S    +G+WS+P+P C
Sbjct: 1334 GKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 1387



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 14/114 (12%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGNWSSPEPTCQVIQCEPLSAPDLGIMNC 272
           N    ++  F C EG  L G   + C   G    W+S  P C+ I C        G  + 
Sbjct: 375 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG-RHT 433

Query: 273 SHPLASFSFTSACTFICS----EGT--ELIGKKKTICES----SGIWSNPSPIC 316
             PL  F F     + C      GT  +LIG+    C S    +G+WS+P+P C
Sbjct: 434 GKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 14/114 (12%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGNWSSPEPTCQVIQCEPLSAPDLGIMNC 272
           N    ++  F C EG  L G   + C   G    W+S  P C+ I C        G  + 
Sbjct: 825 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG-RHT 883

Query: 273 SHPLASFSFTSACTFICS----EGT--ELIGKKKTICES----SGIWSNPSPIC 316
             PL  F F     + C      GT  +LIG+    C S    +G+WS+P+P C
Sbjct: 884 GKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 937



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 37/144 (25%), Positives = 55/144 (38%), Gaps = 31/144 (21%)

Query: 201  EAPELGTMDCTHPLG-----------NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGN 246
            EAP      C   LG           N    ++ +F C EG  L G   + C   G    
Sbjct: 1699 EAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSL 1758

Query: 247  WSSPEPTCQVIQCEPLSAPDLGIMNCSH---PLASFSFTSACTFICSEGTE------LIG 297
            W++  P C+ I C    A    I+N  H   P     +    ++ C    +      LIG
Sbjct: 1759 WNNSVPVCEHIFCPNPPA----ILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIG 1814

Query: 298  KKKTICES----SGIWSNPSPICQ 317
            +    C S    +G+WS+P+P C+
Sbjct: 1815 ESTIRCTSDPHGNGVWSSPAPRCE 1838



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
           WSSP+  C+   C+    P  G++   H +      S   + C+ G  LIG     C  S
Sbjct: 542 WSSPKDVCKRKSCKTPPDPVNGMV---HVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598

Query: 307 G---IWSNPSPICQKL 319
           G    WS   PICQ++
Sbjct: 599 GNAAHWSTKPPICQRI 614



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 247  WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
            WSSP+  C+   C+    P  G++   H +      S   + C+ G  LIG     C  S
Sbjct: 992  WSSPKDVCKRKSCKTPPDPVNGMV---HVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048

Query: 307  G---IWSNPSPICQKL 319
            G    WS   PICQ++
Sbjct: 1049 GNAAHWSTKPPICQRI 1064



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 247  WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
            WSSP+  C+   C+    P  G++   H +      S   + C+ G  LIG     C  S
Sbjct: 1442 WSSPKDVCKRKSCKTPPDPVNGMV---HVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1498

Query: 307  G---IWSNPSPICQKL 319
            G    WS   PICQ++
Sbjct: 1499 GNTAHWSTKPPICQRI 1514



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 37/155 (23%), Positives = 62/155 (40%), Gaps = 17/155 (10%)

Query: 189  PQCQFVIQCEPLEAPELGTMDC-THPLGNFSFSSQCAFSCSEGTN------LTGIEETTC 241
            P C+ +I CEP   P +   D  ++   +F   +   + C  G +      L G     C
Sbjct: 1962 PICE-IISCEP--PPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYC 2018

Query: 242  ----GPFGNWSSPEPTCQVIQCEPLSAPDL-GIMNCSHPLASFSFTSACTFICSEGTELI 296
                   G WSSP P C  I     +AP++   +      + F+ T    F C  G  ++
Sbjct: 2019 TSKDDQVGVWSSPPPRC--ISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMV 2076

Query: 297  GKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDY 331
            G     C+++G W    P C ++ +    I  G++
Sbjct: 2077 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEH 2111



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
           W+  +  C+   C     P  G++   H +    F S   + C++G  LIG     C  S
Sbjct: 92  WTGAKDRCRRKSCRNPPDPVNGMV---HVIKGIQFGSQIKYSCTKGYRLIGSSSATCIIS 148

Query: 307 G---IWSNPSPICQKL 319
           G   IW N +PIC ++
Sbjct: 149 GDTVIWDNETPICDRI 164



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 13/129 (10%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
            NF + S   + C+ G+    + E    P           G WS P P C +  +C P + 
Sbjct: 1534 NFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 1593

Query: 265  PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFS 324
             + GI+  S   + FS      F C  G  + G ++  C++   W    P C ++ +   
Sbjct: 1594 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 1651

Query: 325  MIKEGDYNP 333
             I  G++ P
Sbjct: 1652 EILHGEHTP 1660



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 13/115 (11%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
           NF + S   + C+ G+    + E    P           G WS P P C +  +C P + 
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243

Query: 265 PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
            + GI+  S   + FS      F C  G  + G ++  C++   W    P C ++
Sbjct: 244 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 13/115 (11%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
           NF + S   + C+ G+    + E    P           G WS P P C +  +C P + 
Sbjct: 634 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 693

Query: 265 PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
            + GI+  S   + FS      F C  G  + G ++  C++   W    P C ++
Sbjct: 694 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 13/115 (11%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
            NF + S   + C+ G+    + E    P           G WS P P C +  +C P + 
Sbjct: 1084 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 1143

Query: 265  PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
             + GI+  S   + FS      F C  G  + G ++  C++   W    P C ++
Sbjct: 1144 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 1196



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 20/121 (16%)

Query: 213 PLGNFSFSSQCAFSCS----EGTNLTGIEETTC----GPFGN--WSSPEPTCQVI-QCEP 261
           PL  F F     ++C      GT+   I E+T      P GN  WSSP P C ++  C+ 
Sbjct: 436 PLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ- 494

Query: 262 LSAPD---LGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTI-CESSGIWSNPSPICQ 317
             APD      +      + F   ++  + C    E  G+  +I C  + +WS+P  +C+
Sbjct: 495 --APDHFLFAKLKTQTNASDFPIGTSLKYECR--PEYYGRPFSITCLDNLVWSSPKDVCK 550

Query: 318 K 318
           +
Sbjct: 551 R 551



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 20/121 (16%)

Query: 213  PLGNFSFSSQCAFSCS----EGTNLTGIEETTC----GPFGN--WSSPEPTCQVI-QCEP 261
            PL  F F     ++C      GT+   I E+T      P GN  WSSP P C ++  C+ 
Sbjct: 886  PLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ- 944

Query: 262  LSAPD---LGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTI-CESSGIWSNPSPICQ 317
              APD      +      + F   ++  + C    E  G+  +I C  + +WS+P  +C+
Sbjct: 945  --APDHFLFAKLKTQTNASDFPIGTSLKYECR--PEYYGRPFSITCLDNLVWSSPKDVCK 1000

Query: 318  K 318
            +
Sbjct: 1001 R 1001



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 20/121 (16%)

Query: 213  PLGNFSFSSQCAFSCS----EGTNLTGIEETTC----GPFGN--WSSPEPTCQVI-QCEP 261
            PL  F F     ++C      GT+   I E+T      P GN  WSSP P C ++  C+ 
Sbjct: 1336 PLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ- 1394

Query: 262  LSAPD---LGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTI-CESSGIWSNPSPICQ 317
              APD      +      + F   ++  + C    E  G+  +I C  + +WS+P  +C+
Sbjct: 1395 --APDHFLFAKLKTQTNASDFPIGTSLKYECR--PEYYGRPFSITCLDNLVWSSPKDVCK 1450

Query: 318  K 318
            +
Sbjct: 1451 R 1451



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 29/142 (20%), Positives = 49/142 (34%), Gaps = 12/142 (8%)

Query: 224  AFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCE-PLSAPDLGIMNCSHPLASFSFT 282
            ++ C  G  L G     C   G WS  +  C+ + C  PL     GI         + + 
Sbjct: 2324 SYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMN--GISKELEMKKVYHYG 2381

Query: 283  SACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMV 342
               T  C +G  L G   + C++   W  P   C        ++        FI + +  
Sbjct: 2382 DYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSGTIFFILLII-- 2439

Query: 343  TAFSGLAFIIWLARRLKKGKKS 364
                   F+ W+  + +KG  +
Sbjct: 2440 -------FLSWIILKHRKGNNA 2454


>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
          Length = 2039

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 44/138 (31%), Positives = 59/138 (42%), Gaps = 17/138 (12%)

Query: 197  CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPT 253
            C P   P  G +   H   +  F S   +SC+EG  L G   TTC   GN   W    P 
Sbjct: 1457 CGPPPEPFNGMV---HINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPI 1513

Query: 254  CQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS- 306
            C++I CEP      G    S+   SF   +  T+ C  G       EL+G++   C S  
Sbjct: 1514 CEIISCEPPPTISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKD 1572

Query: 307  ---GIWSNPSPICQKLDK 321
               G+WS+P P C   +K
Sbjct: 1573 DQVGVWSSPPPRCISTNK 1590



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 9/109 (8%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
           NFS   +  +SC  G +L G     C P G+WS   PTC+V  C+      +G +     
Sbjct: 315 NFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF----MGQLLNGRV 370

Query: 276 L--ASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
           L   +    +   F+C EG +L G   + C  +G   +W++  P+C+++
Sbjct: 371 LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 9/109 (8%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
           NFS   +  +SC  G +L G     C P G+WS   PTC+V  C+      +G +     
Sbjct: 765 NFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF----MGQLLNGRV 820

Query: 276 L--ASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
           L   +    +   F+C EG +L G   + C  +G   +W++  P+C+++
Sbjct: 821 LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 869



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 41/155 (26%), Positives = 71/155 (45%), Gaps = 16/155 (10%)

Query: 174  IINNYTCNCDV-GYYGPQCQFVIQ-CEPLEAPEL--GTMDCTHPLGNFSFSSQCAFSCSE 229
            ++ ++T  C   G +GP+     + C+P   PE+  G    +H   NFS   +  +SC  
Sbjct: 1625 MVGSHTVQCQTNGRWGPKLPHCSRVCQP--PPEILHGEHTLSHQ-DNFSPGQEVFYSCEP 1681

Query: 230  GTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL--ASFSFTSACTF 287
              +L G     C P G+WS   P C V  C+      LG +     L   +    +  +F
Sbjct: 1682 SYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDF----LGQLPHGRVLLPLNLQLGAKVSF 1737

Query: 288  ICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
            +C EG  L G+  + C  +G   +W++  P+C+++
Sbjct: 1738 VCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQI 1772



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 16/138 (11%)

Query: 189  PQCQFVIQCEPLEAPEL--GTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN 246
            P C  V  C+P   PE+  G    +H   NFS   +  +SC  G +L G     C P G+
Sbjct: 1191 PSCSRV--CQP--PPEILHGEHTPSHQ-DNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD 1245

Query: 247  WSSPEPTCQVIQCEPLSAPDLGIMNCSHPL--ASFSFTSACTFICSEGTELIGKKKTICE 304
            WS   P C V  C+      LG +     L   +    +  +F+C EG  L G   + C 
Sbjct: 1246 WSPEAPRCAVKSCDDF----LGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCV 1301

Query: 305  SSG---IWSNPSPICQKL 319
              G   +W+N  P+C+ +
Sbjct: 1302 LVGMRSLWNNSVPVCEHI 1319



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
           H +    F SQ  +SC++G  L G    TC   G+   W +  P C  I C  P +  + 
Sbjct: 116 HVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNG 175

Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
             ++ +    +F + S  T+ C+ G+      EL+G+    C S+    GIWS P+P C
Sbjct: 176 DFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 232



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
           H + +    S+  +SC+ G  L G     C   GN   WS+  P CQ I C  P +  + 
Sbjct: 566 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANG 625

Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
             ++ +    +F + S  T+ C+ G+      EL+G+    C S+    GIWS P+P C
Sbjct: 626 DFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 212  HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
            H + +    S+  +SC+ G  L G     C   GN   WS+  P CQ I C  P +  + 
Sbjct: 1016 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANG 1075

Query: 268  GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
              ++ +    +F + S  T+ C+ G+      EL+G+    C S+    GIWS P+P C
Sbjct: 1076 DFISTNR--ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 1132



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 44/172 (25%), Positives = 66/172 (38%), Gaps = 21/172 (12%)

Query: 163  WSCSGH---GECVEIINNYTCNCDVGYYG--------PQCQFVIQCEPLEAPE-LGTMDC 210
            ++C  H   G    +I   T  C    +G        P+C+  ++    + PE       
Sbjct: 1348 YTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASP 1407

Query: 211  THPLGNFSF--SSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLG 268
            T P+ +F F   +   + C  G     +   +C     WSS E  C+   C P   P  G
Sbjct: 1408 TIPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNG 1466

Query: 269  IMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQ 317
            ++   H      F S   + C+EG  LIG   T C  SG    W   +PIC+
Sbjct: 1467 MV---HINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE 1515



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 16/131 (12%)

Query: 213  PLGNFSFSSQCAFSCSEGT------NLTGIEETTC--GPFGN--WSSPEPTCQVIQCEPL 262
            P G+  +  + +++C          NL G     C   P GN  WSSP P C++    P 
Sbjct: 1789 PFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCEL--SVPA 1846

Query: 263  SAPDLGIMNCSHPLAS----FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQK 318
            + P    +   H +      +      ++IC  G  L+GK    C   GIWS     C++
Sbjct: 1847 ACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKE 1906

Query: 319  LDKSFSMIKEG 329
            ++ SF +   G
Sbjct: 1907 VNCSFPLFMNG 1917



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 35/114 (30%), Positives = 48/114 (42%), Gaps = 14/114 (12%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGNWSSPEPTCQVIQCEPLSAPDLGIMNC 272
           N    ++  F C EG  L G   + C   G    W+S  P C+ I C        G  + 
Sbjct: 825 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG-RHT 883

Query: 273 SHPLASFSFTSACTFICS----EGT--ELIGKKKTICES----SGIWSNPSPIC 316
             PL  F F  A  + C      GT  +LIG+    C S    +G+WS+P+P C
Sbjct: 884 GKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 937



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 14/114 (12%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGNWSSPEPTCQVIQCEPLSAPDLGIMNC 272
           N    ++  F C EG  L G   + C   G    W+S  P C+ I C        G  + 
Sbjct: 375 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG-RHT 433

Query: 273 SHPLASFSFTSACTFICS----EGT--ELIGKKKTICES----SGIWSNPSPIC 316
             PL  F F     + C      GT  +LIG+    C S    +G+WS+P+P C
Sbjct: 434 GKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 37/144 (25%), Positives = 55/144 (38%), Gaps = 31/144 (21%)

Query: 201  EAPELGTMDCTHPLG-----------NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGN 246
            EAP      C   LG           N    ++ +F C EG  L G   + C   G    
Sbjct: 1249 EAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSL 1308

Query: 247  WSSPEPTCQVIQCEPLSAPDLGIMNCSH---PLASFSFTSACTFICSEGTE------LIG 297
            W++  P C+ I C    A    I+N  H   P     +    ++ C    +      LIG
Sbjct: 1309 WNNSVPVCEHIFCPNPPA----ILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIG 1364

Query: 298  KKKTICES----SGIWSNPSPICQ 317
            +    C S    +G+WS+P+P C+
Sbjct: 1365 ESTIRCTSDPHGNGVWSSPAPRCE 1388



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
           WSSP+  C+   C+    P  G++   H +      S   + C+ G  LIG     C  S
Sbjct: 542 WSSPKDVCKRKSCKTPPDPVNGMV---HVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598

Query: 307 G---IWSNPSPICQKL 319
           G    WS   PICQ++
Sbjct: 599 GNAAHWSTKPPICQRI 614



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 247  WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
            WSSP+  C+   C+    P  G++   H +      S   + C+ G  LIG     C  S
Sbjct: 992  WSSPKDVCKRKSCKTPPDPVNGMV---HVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048

Query: 307  G---IWSNPSPICQKL 319
            G    WS   PICQ++
Sbjct: 1049 GNTAHWSTKPPICQRI 1064



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 37/155 (23%), Positives = 62/155 (40%), Gaps = 17/155 (10%)

Query: 189  PQCQFVIQCEPLEAPELGTMDC-THPLGNFSFSSQCAFSCSEGTN------LTGIEETTC 241
            P C+ +I CEP   P +   D  ++   +F   +   + C  G +      L G     C
Sbjct: 1512 PICE-IISCEP--PPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYC 1568

Query: 242  ----GPFGNWSSPEPTCQVIQCEPLSAPDL-GIMNCSHPLASFSFTSACTFICSEGTELI 296
                   G WSSP P C  I     +AP++   +      + F+ T    F C  G  ++
Sbjct: 1569 TSKDDQVGVWSSPPPRC--ISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMV 1626

Query: 297  GKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDY 331
            G     C+++G W    P C ++ +    I  G++
Sbjct: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEH 1661



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
           W+  +  C+   C     P  G++   H +    F S   + C++G  LIG     C  S
Sbjct: 92  WTGAKDRCRRKSCRNPPDPVNGMV---HVIKGIQFGSQIKYSCTKGYRLIGSSSATCIIS 148

Query: 307 G---IWSNPSPICQKL 319
           G   IW N +PIC ++
Sbjct: 149 GDTVIWDNETPICDRI 164



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 13/129 (10%)

Query: 216  NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
            NF + S   + C+ G+    + E    P           G WS P P C +  +C P + 
Sbjct: 1084 NFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 1143

Query: 265  PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFS 324
             + GI+  S   + FS      F C  G  + G ++  C++   W    P C ++ +   
Sbjct: 1144 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 1201

Query: 325  MIKEGDYNP 333
             I  G++ P
Sbjct: 1202 EILHGEHTP 1210



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 13/115 (11%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
           NF + S   + C+ G+    + E    P           G WS P P C +  +C P + 
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243

Query: 265 PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
            + GI+  S   + FS      F C  G  + G ++  C++   W    P C ++
Sbjct: 244 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 13/115 (11%)

Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
           NF + S   + C+ G+    + E    P           G WS P P C +  +C P + 
Sbjct: 634 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 693

Query: 265 PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
            + GI+  S   + FS      F C  G  + G ++  C++   W    P C ++
Sbjct: 694 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 20/121 (16%)

Query: 213 PLGNFSFSSQCAFSCS----EGTNLTGIEETTC----GPFGN--WSSPEPTCQVI-QCEP 261
           PL  F F     ++C      GT+   I E+T      P GN  WSSP P C ++  C+ 
Sbjct: 436 PLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ- 494

Query: 262 LSAPD---LGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTI-CESSGIWSNPSPICQ 317
             APD      +      + F   ++  + C    E  G+  +I C  + +WS+P  +C+
Sbjct: 495 --APDHFLFAKLKTQTNASDFPIGTSLKYECR--PEYYGRPFSITCLDNLVWSSPKDVCK 550

Query: 318 K 318
           +
Sbjct: 551 R 551



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 20/121 (16%)

Query: 213  PLGNFSFSSQCAFSCS----EGTNLTGIEETTC----GPFGN--WSSPEPTCQVI-QCEP 261
            PL  F F     ++C      GT+   I E+T      P GN  WSSP P C ++  C+ 
Sbjct: 886  PLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ- 944

Query: 262  LSAPD---LGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTI-CESSGIWSNPSPICQ 317
              APD      +      + F   ++  + C    E  G+  +I C  + +WS+P  +C+
Sbjct: 945  --APDHFLFAKLKTQTNASDFPIGTSLKYECR--PEYYGRPFSITCLDNLVWSSPKDVCK 1000

Query: 318  K 318
            +
Sbjct: 1001 R 1001



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 29/142 (20%), Positives = 49/142 (34%), Gaps = 12/142 (8%)

Query: 224  AFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCE-PLSAPDLGIMNCSHPLASFSFT 282
            ++ C  G  L G     C   G WS  +  C+ + C  PL     GI         + + 
Sbjct: 1874 SYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMN--GISKELEMKKVYHYG 1931

Query: 283  SACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMV 342
               T  C +G  L G   + C++   W  P   C        ++        FI + +  
Sbjct: 1932 DYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSGTIFFILLII-- 1989

Query: 343  TAFSGLAFIIWLARRLKKGKKS 364
                   F+ W+  + +KG  +
Sbjct: 1990 -------FLSWIILKHRKGNNA 2004


>gi|7657619 sushi-repeat-containing protein, X-linked 2 [Homo
           sapiens]
          Length = 465

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 35/118 (29%), Positives = 48/118 (40%), Gaps = 7/118 (5%)

Query: 206 GTMDCTHPLG---NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPL 262
           G   C  P G   + S  ++C  SC  G  L G     C P   WS     C+ ++C  L
Sbjct: 67  GEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHAL 125

Query: 263 SAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLD 320
                G   C++ +      S C + CS G  L G +  IC   G WS   P+C  +D
Sbjct: 126 PFITSGTYTCTNGVL---LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDID 180



 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 3/71 (4%)

Query: 195 IQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC 254
           ++C  L     GT  CT+ +      S+C +SCS G +L G     C   G WS  EP C
Sbjct: 120 MRCHALPFITSGTYTCTNGV---LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176

Query: 255 QVIQCEPLSAP 265
             I    +  P
Sbjct: 177 VDIDPPKIRCP 187



 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 255 QVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSP 314
           QV +C  L  P  G + C+   A  ++ + C + C  G +  G    +C+SS  WS   P
Sbjct: 260 QVRRCPTLKPPQHGYLTCTS--AGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPP 317

Query: 315 IC 316
           IC
Sbjct: 318 IC 319



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 20/77 (25%), Positives = 31/77 (40%), Gaps = 7/77 (9%)

Query: 183 DVGYYGPQCQFVIQ-----CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIE 237
           D  Y    C+F+++     C  L+ P+ G + CT    N+   + C + C  G +  G  
Sbjct: 245 DRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYG--ATCEYHCDGGYDRQGTP 302

Query: 238 ETTCGPFGNWSSPEPTC 254
              C     WS   P C
Sbjct: 303 SRVCQSSRQWSGSPPIC 319


>gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens]
          Length = 292

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 22/138 (15%)

Query: 27  CC--DFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYL-EKTLPFS 83
           CC  +++ H G+  W  H  +    W  A ++C+     LV I +  E +++ + T PF+
Sbjct: 157 CCPVNWVEHQGSCYWFSHSGKA---WAEAEKYCQLENAHLVVINSWEEQKFIVQHTNPFN 213

Query: 84  RSYYWIGIRKIGGIWTWV-GTNKSLTEEAENWGDGEPNN-----KKNKEDCVEIYIKRNK 137
               WIG+    G W WV GT+       +NW   +P+N         EDCVE+     +
Sbjct: 214 T---WIGLTDSDGSWKWVDGTD--YRHNYKNWAVTQPDNWHGHELGGSEDCVEV-----Q 263

Query: 138 DAGKWNDDACHKLKAALC 155
             G+WNDD C ++   +C
Sbjct: 264 PDGRWNDDFCLQVYRWVC 281


>gi|18426875 asialoglycoprotein receptor 2 isoform b [Homo sapiens]
          Length = 287

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 22/138 (15%)

Query: 27  CC--DFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYL-EKTLPFS 83
           CC  +++ H G+  W  H  +    W  A ++C+     LV I +  E +++ + T PF+
Sbjct: 152 CCPVNWVEHQGSCYWFSHSGKA---WAEAEKYCQLENAHLVVINSWEEQKFIVQHTNPFN 208

Query: 84  RSYYWIGIRKIGGIWTWV-GTNKSLTEEAENWGDGEPNN-----KKNKEDCVEIYIKRNK 137
               WIG+    G W WV GT+       +NW   +P+N         EDCVE+     +
Sbjct: 209 T---WIGLTDSDGSWKWVDGTD--YRHNYKNWAVTQPDNWHGHELGGSEDCVEV-----Q 258

Query: 138 DAGKWNDDACHKLKAALC 155
             G+WNDD C ++   +C
Sbjct: 259 PDGRWNDDFCLQVYRWVC 276


>gi|18426873 asialoglycoprotein receptor 2 isoform a [Homo sapiens]
          Length = 311

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 22/138 (15%)

Query: 27  CC--DFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYL-EKTLPFS 83
           CC  +++ H G+  W  H  +    W  A ++C+     LV I +  E +++ + T PF+
Sbjct: 176 CCPVNWVEHQGSCYWFSHSGKA---WAEAEKYCQLENAHLVVINSWEEQKFIVQHTNPFN 232

Query: 84  RSYYWIGIRKIGGIWTWV-GTNKSLTEEAENWGDGEPNN-----KKNKEDCVEIYIKRNK 137
               WIG+    G W WV GT+       +NW   +P+N         EDCVE+     +
Sbjct: 233 T---WIGLTDSDGSWKWVDGTD--YRHNYKNWAVTQPDNWHGHELGGSEDCVEV-----Q 282

Query: 138 DAGKWNDDACHKLKAALC 155
             G+WNDD C ++   +C
Sbjct: 283 PDGRWNDDFCLQVYRWVC 300


>gi|4502253 asialoglycoprotein receptor 2 isoform a [Homo sapiens]
          Length = 311

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 22/138 (15%)

Query: 27  CC--DFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYL-EKTLPFS 83
           CC  +++ H G+  W  H  +    W  A ++C+     LV I +  E +++ + T PF+
Sbjct: 176 CCPVNWVEHQGSCYWFSHSGKA---WAEAEKYCQLENAHLVVINSWEEQKFIVQHTNPFN 232

Query: 84  RSYYWIGIRKIGGIWTWV-GTNKSLTEEAENWGDGEPNN-----KKNKEDCVEIYIKRNK 137
               WIG+    G W WV GT+       +NW   +P+N         EDCVE+     +
Sbjct: 233 T---WIGLTDSDGSWKWVDGTD--YRHNYKNWAVTQPDNWHGHELGGSEDCVEV-----Q 282

Query: 138 DAGKWNDDACHKLKAALC 155
             G+WNDD C ++   +C
Sbjct: 283 PDGRWNDDFCLQVYRWVC 300


>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
           sapiens]
          Length = 569

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 26/161 (16%)

Query: 178 YTCNCDVGYYGP---QCQFVIQCEPLEAPELGTMDCTHP------------LGNFSFSSQ 222
           + C    G  GP   +CQ + + EP E P    + C  P              NFS   +
Sbjct: 256 FRCQPGFGMKGPSHVKCQALNKWEP-ELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQE 313

Query: 223 CAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL--ASFS 280
             +SC  G +L G     C P G+WS   P C+V  C+      LG +   H L   +  
Sbjct: 314 VFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDF----LGQLPNGHVLFPLNLQ 369

Query: 281 FTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQK 318
             +   F+C EG +L G   + C  +G   +W++  P+C++
Sbjct: 370 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCER 410



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 16/119 (13%)

Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
           H + +  F SQ  +SC +G  L G    TC   GN   W +  P C  I C  P +  + 
Sbjct: 108 HVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANG 167

Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
              + S     F + S  T+ C+ G+      EL+G+    C S     GIWS P+P C
Sbjct: 168 DFTSISREY--FHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQC 224



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 41/139 (29%), Positives = 57/139 (41%), Gaps = 16/139 (11%)

Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLG--NFSFSSQCAFSCSEGTNLTGIEETTC---GP 243
           P+C+ V  C+      LG +   H L   N    ++  F C EG  L G   + C   G 
Sbjct: 343 PRCE-VKSCDDF----LGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGM 397

Query: 244 FGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTIC 303
              W+S  P C+   CE    P  G++   H +      S   + C+ G  LIG     C
Sbjct: 398 ESLWNSSVPVCERKSCETPPVPVNGMV---HVITDIHVGSRINYSCTTGHRLIGHSSAEC 454

Query: 304 ESSG---IWSNPSPICQKL 319
             SG    WS   PICQ++
Sbjct: 455 ILSGNTAHWSMKPPICQQI 473



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 39/141 (27%), Positives = 58/141 (41%), Gaps = 22/141 (15%)

Query: 194 VIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSP 250
           V + +  E P +      H + +    S+  +SC+ G  L G     C   GN   WS  
Sbjct: 407 VCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMK 466

Query: 251 EPTCQVIQCEPLSAPDLGIMNCSH---PLASFSFTSACTFICSEGTE------LIGKKKT 301
            P CQ I C    A    I+N  H   PL    +    ++ C    +      LIG+  T
Sbjct: 467 PPICQQIFCPNPPA----ILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGES-T 521

Query: 302 ICESS-----GIWSNPSPICQ 317
           I  +S     G+WS+P+P C+
Sbjct: 522 IRRTSEPHGNGVWSSPAPRCE 542



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 33/130 (25%), Positives = 45/130 (34%), Gaps = 6/130 (4%)

Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS 248
           PQC    +C P        +     L  FS +    F C  G  + G     C     W 
Sbjct: 222 PQCIIPNKCTPPNVENGILVSDNRSL--FSLNEVVEFRCQPGFGMKGPSHVKCQALNKWE 279

Query: 249 SPEPTCQVIQCEPLSAPD-LGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG 307
              P+C  + C+P   PD L          +FS      + C  G +L G     C   G
Sbjct: 280 PELPSCSRV-CQP--PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQG 336

Query: 308 IWSNPSPICQ 317
            WS  +P C+
Sbjct: 337 DWSPAAPRCE 346



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 34/136 (25%), Positives = 52/136 (38%), Gaps = 13/136 (9%)

Query: 187 YGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN 246
           +  QC  V +  P   P   T D   P+G +       + C  G +        C     
Sbjct: 31  FSDQCN-VPEWLPFARPTNLTDDFEFPIGTY-----LNYECRPGYSGRPFS-IICLKNSV 83

Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
           W+S +  C+   C     P  G+   +H +    F S   + C +G  LIG     C  S
Sbjct: 84  WTSAKDKCKRKSCRNPPDPVNGM---AHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIIS 140

Query: 307 G---IWSNPSPICQKL 319
           G   IW N +P+C ++
Sbjct: 141 GNTVIWDNKTPVCDRI 156



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 27/114 (23%), Positives = 43/114 (37%), Gaps = 13/114 (11%)

Query: 217 FSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSAP 265
           F + S   + C+ G+    + E    P           G WS P P C +  +C P +  
Sbjct: 177 FHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVE 236

Query: 266 DLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
           + GI+  S   + FS      F C  G  + G     C++   W    P C ++
Sbjct: 237 N-GIL-VSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRV 288



 Score = 30.0 bits (66), Expect = 3.5
 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 20/103 (19%)

Query: 167 GHGECVEIINNYTCNCDVGYYGPQCQFVIQCEP---LEAPELGTMDCTHPLGNFSFSSQC 223
           GH     I++  T +  +    P CQ +    P   L     GT     PLG+  +  + 
Sbjct: 448 GHSSAECILSGNTAHWSMK--PPICQQIFCPNPPAILNGRHTGT-----PLGDIPYGKEV 500

Query: 224 AFSCS----EGTNLTGIEETTCG----PFGN--WSSPEPTCQV 256
           +++C      G     I E+T      P GN  WSSP P C++
Sbjct: 501 SYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCEL 543


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.469 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,802,333
Number of Sequences: 37866
Number of extensions: 839246
Number of successful extensions: 3927
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 186
Number of HSP's successfully gapped in prelim test: 164
Number of HSP's that attempted gapping in prelim test: 2044
Number of HSP's gapped (non-prelim): 1431
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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