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Search of human proteins with 4506875
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506875 selectin L precursor [Homo sapiens]
(372 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506875 selectin L precursor [Homo sapiens] 818 0.0
gi|157419154 selectin P precursor [Homo sapiens] 359 3e-99
gi|187960042 selectin E precursor [Homo sapiens] 339 2e-93
gi|148886654 polydom [Homo sapiens] 95 1e-19
gi|90991712 CD207 antigen, langerin [Homo sapiens] 68 1e-11
gi|62739188 complement factor H isoform b precursor [Homo sapiens] 66 4e-11
gi|62739186 complement factor H isoform a precursor [Homo sapiens] 66 4e-11
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 66 4e-11
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 66 4e-11
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 66 4e-11
gi|223029384 CD209 molecule isoform 7 [Homo sapiens] 66 6e-11
gi|223029380 CD209 molecule isoform 5 [Homo sapiens] 66 6e-11
gi|4505245 mannose receptor C type 1 precursor [Homo sapiens] 65 1e-10
gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens] 65 1e-10
gi|20149533 Fc fragment of IgE, low affinity II, receptor for (C... 64 2e-10
gi|223029517 CD209 molecule isoform 8 [Homo sapiens] 64 3e-10
gi|223029386 CD209 molecule isoform 3 [Homo sapiens] 64 3e-10
gi|223029382 CD209 molecule isoform 6 [Homo sapiens] 64 3e-10
gi|10863957 CD209 molecule isoform 1 [Homo sapiens] 64 3e-10
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 64 3e-10
gi|33667103 C-type lectin, superfamily member 14 isoform 1 [Homo... 63 4e-10
gi|53832016 C-type lectin, superfamily member 14 isoform 2 [Homo... 63 4e-10
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 62 1e-09
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 62 1e-09
gi|7657619 sushi-repeat-containing protein, X-linked 2 [Homo sap... 61 2e-09
gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens] 60 2e-09
gi|18426875 asialoglycoprotein receptor 2 isoform b [Homo sapiens] 60 2e-09
gi|18426873 asialoglycoprotein receptor 2 isoform a [Homo sapiens] 60 2e-09
gi|4502253 asialoglycoprotein receptor 2 isoform a [Homo sapiens] 60 2e-09
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 60 4e-09
>gi|4506875 selectin L precursor [Homo sapiens]
Length = 372
Score = 818 bits (2114), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDN 60
MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDN
Sbjct: 1 MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDN 60
Query: 61 YTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPN 120
YTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPN
Sbjct: 61 YTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPN 120
Query: 121 NKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTC 180
NKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTC
Sbjct: 121 NKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTC 180
Query: 181 NCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETT 240
NCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETT
Sbjct: 181 NCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETT 240
Query: 241 CGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKK 300
CGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKK
Sbjct: 241 CGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKK 300
Query: 301 TICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKK 360
TICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKK
Sbjct: 301 TICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKK 360
Query: 361 GKKSKRSMNDPY 372
GKKSKRSMNDPY
Sbjct: 361 GKKSKRSMNDPY 372
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 359 bits (921), Expect = 3e-99
Identities = 159/310 (51%), Positives = 206/310 (66%)
Query: 8 QSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAI 67
Q QR ++ I +L ++ L + WTYHYS K +W +R++C++ YTDLVAI
Sbjct: 11 QRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYCQNRYTDLVAI 70
Query: 68 QNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNKED 127
QNK EI+YL K LP+ SYYWIGIRK WTWVGT K+LT EAENW D EPNNK+N ED
Sbjct: 71 QNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADNEPNNKRNNED 130
Query: 128 CVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYY 187
CVEIYIK GKWND+ C K K ALCYTASCQ SCS GEC+E I NYTC+C G+Y
Sbjct: 131 CVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFY 190
Query: 188 GPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNW 247
GP+C++V +C LE P+ M+C+HPLGNFSF+SQC+F C++G + G + C G W
Sbjct: 191 GPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIW 250
Query: 248 SSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG 307
++ P C QC PL P+ G M C H +F S+C+F C EG L+G + C +SG
Sbjct: 251 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 310
Query: 308 IWSNPSPICQ 317
+W+ P+P+C+
Sbjct: 311 VWTAPAPVCK 320
Score = 131 bits (330), Expect = 9e-31
Identities = 58/131 (44%), Positives = 81/131 (61%), Gaps = 1/131 (0%)
Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS 248
P C+ +QC+ LEAP GTMDC HPL F++ S C F C G + G++ C G+WS
Sbjct: 317 PVCK-AVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWS 375
Query: 249 SPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGI 308
+P PTC+ I CEPL +P G M+CS L +F + + C+F C+EG L G C++ G
Sbjct: 376 APLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQ 435
Query: 309 WSNPSPICQKL 319
W+ P+P+CQ L
Sbjct: 436 WTAPAPVCQAL 446
Score = 128 bits (322), Expect = 7e-30
Identities = 66/178 (37%), Positives = 98/178 (55%), Gaps = 8/178 (4%)
Query: 145 DACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYYG---PQCQFVIQCEPLE 201
D H L A Y +SC+ + C G V ++ C D G++ P C+ I CEPLE
Sbjct: 336 DCVHPL-TAFAYGSSCK-FECQP-GYRVRGLDMLRC-IDSGHWSAPLPTCE-AISCEPLE 390
Query: 202 APELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEP 261
+P G+MDC+ L F + + C+F C+EG L G + C G W++P P CQ +QC+
Sbjct: 391 SPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQD 450
Query: 262 LSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
L P+ +NCSHP +F + S C+F C+EG L+G C ++G W++ P CQ +
Sbjct: 451 LPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAI 508
Score = 126 bits (316), Expect = 4e-29
Identities = 72/221 (32%), Positives = 99/221 (44%), Gaps = 27/221 (12%)
Query: 125 KEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHG--ECVEIIN--NYTC 180
K +C Y R D + D C SC+P HG +C + Y
Sbjct: 351 KFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDT 410
Query: 181 NC-------------------DVGYY---GPQCQFVIQCEPLEAPELGTMDCTHPLGNFS 218
NC ++G + P CQ +QC+ L P ++C+HP G F
Sbjct: 411 NCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQ-ALQCQDLPVPNEARVNCSHPFGAFR 469
Query: 219 FSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLAS 278
+ S C+F+C+EG L G C GNW+S P CQ I C PL +P G M C PL S
Sbjct: 470 YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGS 529
Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
S+ S C FIC EG L G ++ C SG W++ P+C+ +
Sbjct: 530 SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAI 570
Score = 114 bits (285), Expect = 1e-25
Identities = 53/129 (41%), Positives = 70/129 (54%), Gaps = 1/129 (0%)
Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS 248
P+CQ I C PL +P+ GTM C PLG+ S+ S C F C EG +L+G E C G W+
Sbjct: 503 PECQ-AIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWT 561
Query: 249 SPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGI 308
P C+ I+C L AP+ G ++CS F+ S C F C G +L G C +SG
Sbjct: 562 DSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGR 621
Query: 309 WSNPSPICQ 317
WS P C+
Sbjct: 622 WSATPPTCK 630
Score = 106 bits (265), Expect = 3e-23
Identities = 63/206 (30%), Positives = 88/206 (42%), Gaps = 27/206 (13%)
Query: 139 AGKWNDDA--CHKLKAALCYTASCQPWSCSG-----------HGEC-----VEIINNYTC 180
+G+W D C +K + CS H C +E NN C
Sbjct: 557 SGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVEC 616
Query: 181 NCDVGYYG--PQCQFV-------IQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGT 231
+ P C+ + +QC L P GTM C H G F F++ C F C+ G
Sbjct: 617 TTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGF 676
Query: 232 NLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSE 291
L G +C P G W++ P C+ ++C L MNCS+ +FS+ S C+F C E
Sbjct: 677 TLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLE 736
Query: 292 GTELIGKKKTICESSGIWSNPSPICQ 317
G L G +T C+ +G WS P CQ
Sbjct: 737 GQLLNGSAQTACQENGHWSTTVPTCQ 762
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 339 bits (870), Expect = 2e-93
Identities = 147/279 (52%), Positives = 187/279 (67%)
Query: 39 WTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIW 98
W+Y+ S + M + A +C+ YT LVAIQNK EIEYL L +S SYYWIGIRK+ +W
Sbjct: 22 WSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVW 81
Query: 99 TWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTA 158
WVGT K LTEEA+NW GEPNN++ EDCVEIYIKR KD G WND+ C K K ALCYTA
Sbjct: 82 VWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTA 141
Query: 159 SCQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFS 218
+C SCSGHGECVE INNYTC CD G+ G +C+ ++ C LE+PE G++ C+HPLGNFS
Sbjct: 142 ACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFS 201
Query: 219 FSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLAS 278
++S C+ SC G + +E C G WS+P P C V++C+ ++ P G + C S
Sbjct: 202 YNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGS 261
Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQ 317
F + + CTF C EG EL+G + C SSG W N P C+
Sbjct: 262 FPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK 300
Score = 114 bits (284), Expect = 2e-25
Identities = 55/146 (37%), Positives = 79/146 (54%), Gaps = 4/146 (2%)
Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPL-GNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNW 247
P C+ QC L PE G M+C G+F + S C FSC +G L G + CGP G W
Sbjct: 360 PVCE-AFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEW 418
Query: 248 SSPEPTCQVIQCEPLSAPDLGIMNCSH-PLASFSFTSACTFICSEGTELIGKKKTICESS 306
+ +PTC+ ++C+ + P G++ C+H P+ F++ S+C F C EG EL G + C S
Sbjct: 419 DNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQ 478
Query: 307 GIWSNPSPICQKLDKSFSMIKEGDYN 332
G W+ P CQ + K S+ G N
Sbjct: 479 GQWTEEVPSCQVV-KCSSLAVPGKIN 503
Score = 103 bits (258), Expect = 2e-22
Identities = 49/131 (37%), Positives = 68/131 (51%), Gaps = 3/131 (2%)
Query: 189 PQCQFVIQCEPLEAPELGTMDCTH-PLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNW 247
P C+ + C + P+ G++ C+H P G F+F S C F+C EG L G + C G W
Sbjct: 297 PTCK-AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQW 355
Query: 248 SSPEPTCQVIQCEPLSAPDLGIMNC-SHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
+ P C+ QC LS P+ G MNC SF + S+C F C +G L G K+ C +
Sbjct: 356 TQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPT 415
Query: 307 GIWSNPSPICQ 317
G W N P C+
Sbjct: 416 GEWDNEKPTCE 426
Score = 103 bits (258), Expect = 2e-22
Identities = 60/178 (33%), Positives = 89/178 (50%), Gaps = 16/178 (8%)
Query: 189 PQCQFVIQCEPLEAPELGTMDCTH-PLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNW 247
P C+ ++C+ + P G + C H P+G F++ S CAFSC EG L G + C G W
Sbjct: 423 PTCE-AVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQW 481
Query: 248 SSPEPTCQVIQCEPLSAPDLGIMNCS-HPLASFSFTSACTFICSEGTELIGKKKTICESS 306
+ P+CQV++C L+ P M+CS P+ F + C F C EG L G C ++
Sbjct: 482 TEEVPSCQVVKCSSLAVPGKINMSCSGEPV----FGTVCKFACPEGWTLNGSAARTCGAT 537
Query: 307 GIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLA-FIIWLARRLKKGKK 363
G WS P C+ +S PL ++ + LA F++WL + L+K KK
Sbjct: 538 GHWSGLLPTCEAPTES--------NIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKK 587
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 94.7 bits (234), Expect = 1e-19
Identities = 61/198 (30%), Positives = 91/198 (45%), Gaps = 17/198 (8%)
Query: 138 DAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYYGP--QCQFVI 195
D G WN + L C S CS H C+ + +Y C+C Y G C I
Sbjct: 1732 DNGSWNGVSPSCLDVDECAVGS----DCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPI 1787
Query: 196 QCEPLEAPELGTMDCTHPLGN-FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC 254
+C+ PE G H G ++ ++ FSC EG L G+ + TC G W+ P C
Sbjct: 1788 KCKAPGNPENG-----HSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYC 1842
Query: 255 QVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSP 314
+ + C + P+ G C LA F+F S T+ C++G L G K++ C ++ WS+ P
Sbjct: 1843 KAVSCGKPAIPENG---CIEELA-FTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPP 1898
Query: 315 ICQKLD-KSFSMIKEGDY 331
+C+ + S I G Y
Sbjct: 1899 VCEPVKCSSPENINNGKY 1916
Score = 75.5 bits (184), Expect = 7e-14
Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 8/179 (4%)
Query: 158 ASCQPWSCSGHGECVEIINNYTCNCDVGYY--GPQCQFVIQCEPLEAPELGTMDCTHPLG 215
+SC P H + C C GY G C+ V C L+ PE G
Sbjct: 338 SSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELV-HCPALKPPENGYF--IQNTC 394
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
N F++ C C G +L G C P G WS E C+V C L P G ++CS
Sbjct: 395 NNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCS-- 452
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC-QKLDKSFSMIKEGDYNP 333
+ + C C EG L G K C+ + W P P C ++ +F M K+ +P
Sbjct: 453 TREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISP 511
Score = 71.2 bits (173), Expect = 1e-12
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 10/133 (7%)
Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS 248
P C+ V+ C P P L + P F S +SC G L G T C P G WS
Sbjct: 2374 PVCKIVL-CTP---PPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWS 2429
Query: 249 SPEPTCQVIQC-EPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG 307
SP P C ++C +P P+ GI++ + ++ S + C G EL+G T+C +G
Sbjct: 2430 SPLPECVPVECPQPEEIPN-GIID----VQGLAYLSTALYTCKPGFELVGNTTTLCGENG 2484
Query: 308 IWSNPSPICQKLD 320
W P C+ ++
Sbjct: 2485 HWLGGKPTCKAIE 2497
Score = 67.8 bits (164), Expect = 2e-11
Identities = 39/128 (30%), Positives = 65/128 (50%), Gaps = 5/128 (3%)
Query: 195 IQCEPLEAPELGTMDCTHPLG-NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPT 253
IQC P+ E ++ + G N+SF + A+SC++G + G +++TC G WSSP PT
Sbjct: 2139 IQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPT 2198
Query: 254 CQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPS 313
C + C + G + H F S + C+ G + +G +C+++ W + S
Sbjct: 2199 CHPVSCGEPPKVENGFL--EHTTGRI-FESEVRYQCNPGYKSVGSPVFVCQANRHWHSES 2255
Query: 314 PI-CQKLD 320
P+ C LD
Sbjct: 2256 PLMCVPLD 2263
Score = 61.6 bits (148), Expect = 1e-09
Identities = 39/148 (26%), Positives = 68/148 (45%), Gaps = 15/148 (10%)
Query: 176 NNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPL---GNFSFSSQCAFSCSEGTN 232
+ +TC D ++ + I C P + P + TH L +FS + Q + SC+EG
Sbjct: 3159 DTFTCQKDGRWFPER----ISCSPKKCPL--PENITHILVHGDDFSVNRQVSVSCAEGYT 3212
Query: 233 LTGIEETTCGPFGNWSSP--EPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICS 290
G+ + C G W P + +C + C +P+ G + S ++F S + C
Sbjct: 3213 FEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGS----KYTFESTIIYQCE 3268
Query: 291 EGTELIGKKKTICESSGIWSNPSPICQK 318
G EL G ++ +C+ + WS IC++
Sbjct: 3269 PGYELEGNRERVCQENRQWSGGVAICKE 3296
Score = 61.2 bits (147), Expect = 1e-09
Identities = 36/122 (29%), Positives = 51/122 (41%), Gaps = 4/122 (3%)
Query: 196 QCEPLEAPELGTMDCTHPLGNFSFS-SQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC 254
+C P + PE ++ L + FSC EG L G C P W+ P C
Sbjct: 2317 KCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVC 2376
Query: 255 QVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSP 314
+++ C P P L P ++ F S + C G L G T+C+ G WS+P P
Sbjct: 2377 KIVLCTP---PPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLP 2433
Query: 315 IC 316
C
Sbjct: 2434 EC 2435
Score = 60.5 bits (145), Expect = 2e-09
Identities = 36/116 (31%), Positives = 48/116 (41%), Gaps = 8/116 (6%)
Query: 204 ELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLS 263
E GT++ T +F C +G L G+ E TC G WSS P C+ C L
Sbjct: 3013 EYGTVNGT----DFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP 3068
Query: 264 APDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
I N S + T+ C G + G IC G+WS P P+C+ L
Sbjct: 3069 M----IPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 3120
Score = 58.5 bits (140), Expect = 9e-09
Identities = 33/101 (32%), Positives = 53/101 (52%), Gaps = 4/101 (3%)
Query: 217 FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPD-LGIMNCSHP 275
F+ S +F C EG L + C G W+ P+ IQC P+ + IMN
Sbjct: 2102 FAAGSVVSFKCMEGFVLNTSAKIECMRGGQWN---PSPMSIQCIPVRCGEPPSIMNGYAS 2158
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
+++SF + + C++G + G+KK+ CE++G WS+P P C
Sbjct: 2159 GSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2199
Score = 58.5 bits (140), Expect = 9e-09
Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 9/134 (6%)
Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS 248
P C I+C+ APE G + T S S +SC G L G + C WS
Sbjct: 2710 PSC-ISIECDLPTAPENGFLRFTET----SMGSAVQYSCKPGHILAGSDLRLCLENRKWS 2764
Query: 249 SPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGI 308
P C+ I C+ + +MN S +++++ S + C G L G ++ C+
Sbjct: 2765 GASPRCEAISCKKPNP----VMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKN 2820
Query: 309 WSNPSPICQKLDKS 322
W PIC +D S
Sbjct: 2821 WDEDEPICIPVDCS 2834
Score = 58.5 bits (140), Expect = 9e-09
Identities = 37/119 (31%), Positives = 49/119 (41%), Gaps = 8/119 (6%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
++ F + F C EG L G + TC GNW + P C+ + C P G N
Sbjct: 2906 DYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPN---- 2961
Query: 276 LASFSFTSA--CTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYN 332
FSF + C G +L G C S+G WS SP C S +I+ G N
Sbjct: 2962 --GFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVN 3018
Score = 58.2 bits (139), Expect = 1e-08
Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 13/129 (10%)
Query: 196 QCEPLEAPEL-----GTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSP 250
+C P+E P+ G +D + ++ S ++C G L G T CG G+W
Sbjct: 2434 ECVPVECPQPEEIPNGIID----VQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGG 2489
Query: 251 EPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWS 310
+PTC+ I+C I+N + T+ C+ G L G C +G W
Sbjct: 2490 KPTCKAIEC----LKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWD 2545
Query: 311 NPSPICQKL 319
+P C +
Sbjct: 2546 VDAPSCNAI 2554
Score = 58.2 bits (139), Expect = 1e-08
Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 4/104 (3%)
Query: 217 FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL 276
++F + ++C+EG L G C G+WS P C ++C + P L N
Sbjct: 2849 YTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC--ATPPQLA--NGVTEG 2904
Query: 277 ASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLD 320
+ F TF C EG L G K C+S G W P+C+ ++
Sbjct: 2905 LDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN 2948
Score = 57.4 bits (137), Expect = 2e-08
Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 4/104 (3%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NF + + +++C+ G L G C G W+ P+C I+C+ +AP+ G +
Sbjct: 2674 NFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLR---- 2729
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
S SA + C G L G +C + WS SP C+ +
Sbjct: 2730 FTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAI 2773
Score = 57.4 bits (137), Expect = 2e-08
Identities = 31/103 (30%), Positives = 46/103 (44%), Gaps = 8/103 (7%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCE--PLSAPDLGIMNCS 273
N+++ S + C G L G E TC NW EP C + C P+SA N
Sbjct: 2790 NYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSA------NGQ 2843
Query: 274 HPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
++F + C+EG L G + +C ++G WS +P C
Sbjct: 2844 VRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC 2886
Score = 56.6 bits (135), Expect = 3e-08
Identities = 42/178 (23%), Positives = 68/178 (38%), Gaps = 32/178 (17%)
Query: 160 CQPWSCSG-----HGECV----EIINNYTCNCDVGY--YGPQCQFVIQCEPL-----EAP 203
C+P CS +G+ + ++ + +CD GY GP +I+C P
Sbjct: 1900 CEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPS---IIECTASGIWDRAPP 1956
Query: 204 ELGTMDCTHPLG---------NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC 254
+ C P NF+F + ++C EG L G++ C G WS + C
Sbjct: 1957 ACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQC 2016
Query: 255 QVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNP 312
+ C+ D +H L F + CS+G L + +C + G W P
Sbjct: 2017 LAVSCDEPPIVDHASPETAHRL----FGDIAFYYCSDGYSLADNSQLLCNAQGKWVPP 2070
Score = 56.2 bits (134), Expect = 5e-08
Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 14/127 (11%)
Query: 203 PELGTMDCTHPL----GNFSFSS-----QCAFSCSEGTNLTGIEETTCGPFGNWSSPEPT 253
P ++C P G FS++ +SC+ G L G TC G+W P+
Sbjct: 2491 PTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPS 2550
Query: 254 CQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPS 313
C I C+ + G + A +S+ + + C G ++ G CE SG WS+
Sbjct: 2551 CNAIHCDSPQPIENGFVEG----ADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSI 2605
Query: 314 PICQKLD 320
P C +D
Sbjct: 2606 PTCMPID 2612
Score = 54.3 bits (129), Expect = 2e-07
Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 14/158 (8%)
Query: 164 SCSGHGECVEIINNYTCNCDVGYYGP----QCQFVIQCEPLEAPELGTMDCTHPLGNFSF 219
SC+ G E +N C D + P C + C E+PE G + + ++F
Sbjct: 3206 SCA-EGYTFEGVNISVCQLDGTWEPPFSDESCS-PVSCGKPESPEHGFVVGS----KYTF 3259
Query: 220 SSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASF 279
S + C G L G E C WS C+ +CE L +N + +
Sbjct: 3260 ESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCE----TPLEFLNGKADIENR 3315
Query: 280 SFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQ 317
+ + C+ G L G + C +G WS+P P+C+
Sbjct: 3316 TTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCK 3353
Score = 53.1 bits (126), Expect = 4e-07
Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 9/123 (7%)
Query: 197 CEPLE--APELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC 254
CEP++ +PE + + L ++ S ++SC G +L G C G W P C
Sbjct: 1900 CEPVKCSSPE-NINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPAC 1958
Query: 255 QVIQC-EPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPS 313
++ C EP + D I +F+F + T+ C EG L G C + G WS
Sbjct: 1959 HLVFCGEPPAIKDAVITG-----NNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSD 2013
Query: 314 PIC 316
C
Sbjct: 2014 QQC 2016
Score = 51.6 bits (122), Expect = 1e-06
Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 227 CSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACT 286
C G L G C G W+ P P C+ I C + P + N H F S T
Sbjct: 1658 CDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCG-VPPP---LENGFHSADDFYAGSTVT 1713
Query: 287 FICSEGTELIGKKKTICESSGIWSNPSPICQKLDK 321
+ C+ G L+G + C +G W+ SP C +D+
Sbjct: 1714 YQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDE 1748
Score = 50.4 bits (119), Expect = 2e-06
Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 5/101 (4%)
Query: 217 FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL 276
F + C EG L G TC P W+ C+ I C P + + I H
Sbjct: 3374 FYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVH-- 3431
Query: 277 ASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQ 317
+ + T+ C G L G +++C +G W++P PIC+
Sbjct: 3432 --YQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSP-PICR 3469
Score = 48.1 bits (113), Expect = 1e-05
Identities = 41/198 (20%), Positives = 69/198 (34%), Gaps = 58/198 (29%)
Query: 178 YTCNCDVGYYGPQCQFVIQCEP--LEAPELGTMDCTHPL---------GNFSFSSQCAFS 226
Y+CN GP ++ ++AP + C P ++S+ + +S
Sbjct: 2522 YSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYS 2581
Query: 227 CSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCS------------- 273
C G + G TC G WSS PTC I C P + +C+
Sbjct: 2582 CFPGFQVAGHAMQTCEESG-WSSSIPTCMPIDCG--LPPHIDFGDCTKLKDDQGYFEQED 2638
Query: 274 ----------HP---------------------LASFSFTSACTFICSEGTELIGKKKTI 302
HP ++F + + ++ C+ G EL+G I
Sbjct: 2639 DMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLI 2698
Query: 303 CESSGIWSNPSPICQKLD 320
C+ G W+ +P C ++
Sbjct: 2699 CQEDGTWNGSAPSCISIE 2716
Score = 47.8 bits (112), Expect = 2e-05
Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 5/103 (4%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NF S+ F C+EG L G TC G W+ +C P P+ ++
Sbjct: 2279 NFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNP----KCMPAKCPEPPLLENQLV 2334
Query: 276 LASFSF-TSACTFICSEGTELIGKKKTICESSGIWSNPSPICQ 317
L + TF C EG L G C S W++ P+C+
Sbjct: 2335 LKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2377
Score = 45.4 bits (106), Expect = 8e-05
Identities = 37/125 (29%), Positives = 49/125 (39%), Gaps = 7/125 (5%)
Query: 196 QCEPLEAPELGTMDCTHP-LGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPE--- 251
QC + E +D P + F + CS+G +L + C G W PE
Sbjct: 2015 QCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQD 2074
Query: 252 -PTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWS 310
P C CE + I+ S A F+ S +F C EG L K C G W
Sbjct: 2075 MPRCIAHFCEKPPSVSYSILE-SVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQW- 2132
Query: 311 NPSPI 315
NPSP+
Sbjct: 2133 NPSPM 2137
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 5/96 (5%)
Query: 225 FSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCE-PLSAPDLGIMNCSHPLASFSFTS 283
+SC+ G +L G E C G WS P P C+ C P P+ +++ F
Sbjct: 3323 YSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLS----EKEFYVDQ 3378
Query: 284 ACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
+ C EG L G C W+ S C+K+
Sbjct: 3379 NVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKI 3414
Score = 43.1 bits (100), Expect = 4e-04
Identities = 32/145 (22%), Positives = 49/145 (33%), Gaps = 41/145 (28%)
Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC----------------- 254
H +F S + C+ G L G C G+W+ P+C
Sbjct: 1701 HSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHAS 1760
Query: 255 -------QVIQCEPLSAPDLGIMNCSHPLAS---------------FSFTSACTFICSEG 292
+ C P D NC+ P+ ++ + TF C EG
Sbjct: 1761 CLNVDGSYICSCVPPYTGD--GKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEG 1818
Query: 293 TELIGKKKTICESSGIWSNPSPICQ 317
+L+G K C SG W++ P C+
Sbjct: 1819 YQLMGVTKITCLESGEWNHLIPYCK 1843
Score = 37.0 bits (84), Expect = 0.029
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 8/89 (8%)
Query: 148 HKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVI-QCEPLEAPELG 206
H++ + + + P C G C ++ Y C C +GY G +C+ I +C PL P L
Sbjct: 1187 HEISSQVFHECFFNP--CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPL--PCLN 1242
Query: 207 TMDCTHPLGNFSFSSQCAFS---CSEGTN 232
C +G F ++ C E N
Sbjct: 1243 NGVCKDLVGEFICECPSGYTGQRCEENIN 1271
Score = 37.0 bits (84), Expect = 0.029
Identities = 12/33 (36%), Positives = 19/33 (57%)
Query: 160 CQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQ 192
CQ C CV+ +N+Y+C C G+ G +C+
Sbjct: 1387 CQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 36.2 bits (82), Expect = 0.049
Identities = 23/86 (26%), Positives = 34/86 (39%), Gaps = 5/86 (5%)
Query: 225 FSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSA 284
+SC G + G + C G WS P P C+ + C S P + N + ++ S
Sbjct: 3088 YSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCG--SPP--SVANAVATGEAHTYESE 3143
Query: 285 CTFICSEGTELIGKKKTI-CESSGIW 309
C EG + T C+ G W
Sbjct: 3144 VKLRCLEGYTMDTDTDTFTCQKDGRW 3169
Score = 32.7 bits (73), Expect = 0.54
Identities = 17/58 (29%), Positives = 23/58 (39%), Gaps = 1/58 (1%)
Query: 160 CQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNF 217
C C G CV+ + Y C C G+ G C+ + E P L C +G F
Sbjct: 1273 CSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVN-ECQSNPCLNNAVCEDQVGGF 1329
Score = 31.6 bits (70), Expect = 1.2
Identities = 11/37 (29%), Positives = 18/37 (48%)
Query: 283 SACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
S C G +L+G C + G W+ P P C+++
Sbjct: 1652 SKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERI 1688
Score = 30.4 bits (67), Expect = 2.7
Identities = 20/80 (25%), Positives = 33/80 (41%), Gaps = 6/80 (7%)
Query: 179 TCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLG-NFSFSSQCAFSCSEGTNLTGIE 237
TCN D + Q +CE + ++ G ++ + +SC G L G
Sbjct: 3397 TCNPDETW----TQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFL 3452
Query: 238 ETTCGPFGNWSSPEPTCQVI 257
+ C G W+SP P C+ +
Sbjct: 3453 RSVCLENGTWTSP-PICRAV 3471
Score = 29.6 bits (65), Expect = 4.6
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 11/108 (10%)
Query: 169 GECVEIINNYTCNCDVGYYGPQCQFVIQ-CEPLEAPELGTMDCTHPLGN--FSFSSQCAF 225
G +E + TC + + GP+ + V + C + P+ + H G F + C
Sbjct: 469 GYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPK-DVIISPHNCGKQPAKFGTICYV 527
Query: 226 SCSEGTNLTGIEE-TTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNC 272
SC +G L+G++E C G W+ Q C+ + AP + NC
Sbjct: 528 SCRQGFILSGVKEMLRCTTSGKWN---VGVQAAVCKDVEAPQI---NC 569
Score = 29.6 bits (65), Expect = 4.6
Identities = 25/104 (24%), Positives = 37/104 (35%), Gaps = 5/104 (4%)
Query: 160 CQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSF 219
CQ C + C + + + C C G+ G +C + E L P C G SF
Sbjct: 1311 CQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVD-ECLSQPCKNGATCKD--GANSF 1367
Query: 220 SSQCAFSCSEGTNLTGIEETTCGPFGNWSS--PEPTCQVIQCEP 261
CA + I E P N ++ E +C+P
Sbjct: 1368 RCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQP 1411
>gi|90991712 CD207 antigen, langerin [Homo sapiens]
Length = 328
Score = 68.2 bits (165), Expect = 1e-11
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query: 41 YHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIW 98
Y++S P W A +FC + L ++ +++E E+L KT YWIG+ K G G W
Sbjct: 207 YYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTA--GGLIYWIGLTKAGMEGDW 264
Query: 99 TWV-GTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
+WV T + + W GEPNN N E C I + WND C K +C
Sbjct: 265 SWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNI---KAPSLQAWNDAPCDKTFLFIC 319
>gi|62739188 complement factor H isoform b precursor [Homo sapiens]
Length = 449
Score = 66.2 bits (160), Expect = 4e-11
Identities = 53/181 (29%), Positives = 83/181 (45%), Gaps = 17/181 (9%)
Query: 163 WSCSGHGECVEIINNYTCNCDVGYYG--PQCQFVIQCEPLEAPELGTM--DCTHPLGNFS 218
++C+ + + IN C+ D G+ P C+ V++C P+ APE G + P +
Sbjct: 112 YTCNEGYQLLGEINYRECDTD-GWTNDIPICE-VVKCLPVTAPENGKIVSSAMEPDREYH 169
Query: 219 FSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLAS 278
F F C+ G + G EE C G WS +P C I C+ +PD ++N S P++
Sbjct: 170 FGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCK---SPD--VINGS-PISQ 223
Query: 279 ---FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLF 335
+ + C+ G E + +C SG W P P C++ I GDY+PL
Sbjct: 224 KIIYKENERFQYKCNMGYEYSERGDAVCTESG-W-RPLPSCEEKSCDNPYIPNGDYSPLR 281
Query: 336 I 336
I
Sbjct: 282 I 282
>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
Length = 1231
Score = 66.2 bits (160), Expect = 4e-11
Identities = 53/181 (29%), Positives = 83/181 (45%), Gaps = 17/181 (9%)
Query: 163 WSCSGHGECVEIINNYTCNCDVGYYG--PQCQFVIQCEPLEAPELGTM--DCTHPLGNFS 218
++C+ + + IN C+ D G+ P C+ V++C P+ APE G + P +
Sbjct: 112 YTCNEGYQLLGEINYRECDTD-GWTNDIPICE-VVKCLPVTAPENGKIVSSAMEPDREYH 169
Query: 219 FSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLAS 278
F F C+ G + G EE C G WS +P C I C+ +PD ++N S P++
Sbjct: 170 FGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCK---SPD--VINGS-PISQ 223
Query: 279 ---FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLF 335
+ + C+ G E + +C SG W P P C++ I GDY+PL
Sbjct: 224 KIIYKENERFQYKCNMGYEYSERGDAVCTESG-W-RPLPSCEEKSCDNPYIPNGDYSPLR 281
Query: 336 I 336
I
Sbjct: 282 I 282
Score = 51.2 bits (121), Expect = 1e-06
Identities = 38/133 (28%), Positives = 62/133 (46%), Gaps = 7/133 (5%)
Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLG-NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNW 247
P C I C E GT++ + +++ ++ +++C G ++ ETTC G W
Sbjct: 862 PLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTC-YMGKW 920
Query: 248 SSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG 307
SSP P C+ + C+ S P++ +H S+ + T+ C EG + G C
Sbjct: 921 SSP-PQCEGLPCK--SPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEK 977
Query: 308 IWSNPSPICQKLD 320
WS+P P C K D
Sbjct: 978 -WSHP-PSCIKTD 988
Score = 38.5 bits (88), Expect = 0.010
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 214 LGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQ--VIQCEPLSAPDLGIMN 271
+ + + + C + G EE C GNW+ P P C+ +C P D G +
Sbjct: 1064 MSKYPSGERVRYQCRSPYEMFGDEEVMCLN-GNWTEP-PQCKDSTGKCGPPPPIDNGDIT 1121
Query: 272 CSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
S PL+ ++ S+ + C +L G K+ C +G WS P P C
Sbjct: 1122 -SFPLSVYAPASSVEYQCQNLYQLEGNKRITCR-NGQWSEP-PKC 1163
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 66.2 bits (160), Expect = 4e-11
Identities = 46/184 (25%), Positives = 69/184 (37%), Gaps = 30/184 (16%)
Query: 159 SCQPWSC-----------SGHGECVEIINNYTCNCDVGYYGP---QCQF----------- 193
SC P SC SG+G + ++CN GP QCQ
Sbjct: 2829 SCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMC 2888
Query: 194 -VIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEP 252
V+ C P + GNF++ + + C+ G L G C P G W P P
Sbjct: 2889 KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLP 2948
Query: 253 TCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNP 312
C +I C P +++ ++F S + C+ L+G+ C+ +G WS
Sbjct: 2949 ECIMIDCGHPGVPPNAVLSGE----KYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGS 3004
Query: 313 SPIC 316
P C
Sbjct: 3005 QPHC 3008
Score = 62.4 bits (150), Expect = 6e-10
Identities = 35/129 (27%), Positives = 53/129 (41%), Gaps = 9/129 (6%)
Query: 201 EAPELGTMDCTHP--------LGN-FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPE 251
+ P + C HP GN F+F+ FSC+ G + G + C WS P
Sbjct: 2826 QLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP 2885
Query: 252 PTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSN 311
P C+V+ C P +F++ + + C+ G L G IC+ +G W
Sbjct: 2886 PMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDK 2945
Query: 312 PSPICQKLD 320
P P C +D
Sbjct: 2946 PLPECIMID 2954
Score = 57.4 bits (137), Expect = 2e-08
Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 4/107 (3%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
N+ + + C+ G L G C NWS P+C + C +P G + +
Sbjct: 2792 NYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN-- 2849
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKS 322
F+F TF C+ G + G K C+++ WS+P P+C+ ++ S
Sbjct: 2850 --GFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCS 2894
Score = 57.4 bits (137), Expect = 2e-08
Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NF S ++C G L G EE TC G+W+ +P C+ +QC P
Sbjct: 3031 NFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQC---GNPGTTANGKVFR 3087
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
+ +F+S+ + C EG L G C ++G WS P C
Sbjct: 3088 IDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 3128
Score = 55.1 bits (131), Expect = 1e-07
Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS--SPEPTCQVIQCEPLSAPDLGIMNCS 273
++ + ++ FSC G + G C P G WS + P CQ+I C L P G +
Sbjct: 2674 HYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNG----N 2729
Query: 274 HPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
S+ S F C G L+G C SSG+WS C
Sbjct: 2730 KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2772
Score = 54.3 bits (129), Expect = 2e-07
Identities = 45/169 (26%), Positives = 59/169 (34%), Gaps = 29/169 (17%)
Query: 168 HGECVEIINNYTCNCDVGYYG--------------------PQCQFVIQCEPLEAPELGT 207
+G E +CD GY+G P CQ +I C L P G
Sbjct: 2671 NGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQ-IISCGELPTPPNGN 2729
Query: 208 MDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDL 267
T S+ S F+C G L G C G WS E C C P+L
Sbjct: 2730 KIGTQT----SYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHC---GIPEL 2782
Query: 268 GIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
I+N ++ + + C+ G LIG IC+ WS P C
Sbjct: 2783 -IVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSC 2830
Score = 52.8 bits (125), Expect = 5e-07
Identities = 50/200 (25%), Positives = 73/200 (36%), Gaps = 31/200 (15%)
Query: 140 GKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCN------CDVGY--YGPQC 191
G W+ H A T +C GHG E +N+ CD GY +G +
Sbjct: 2999 GHWSGSQPHCSGDA---TGTCGDPGTPGHGSRQE--SNFRTKSTVRYACDTGYILHGSEE 3053
Query: 192 QFVIQCEPLEA--PELGTMDCTHP----------LGNFSFSSQCAFSCSEGTNLTGIEET 239
+ + PE + C +P + +FSS +SC EG L+G
Sbjct: 3054 RTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVR 3113
Query: 240 TCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEG--TELIG 297
C G WS P C +I C P G+ + +++C G EL G
Sbjct: 3114 QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGD----DYVVGQNVSYMCQPGYTMELNG 3169
Query: 298 KKKTICESSGIWSNPSPICQ 317
+ C +G WS P C+
Sbjct: 3170 SRIRTCTINGTWSGVMPTCR 3189
Score = 51.6 bits (122), Expect = 1e-06
Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 4/101 (3%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NF + ++ CS G L+ TC G WS P C C P G
Sbjct: 3208 NFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG----KRE 3263
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
SF + S +F C+ L+G IC++ G WS SP C
Sbjct: 3264 GKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3304
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 10/98 (10%)
Query: 220 SSQCAFSCSEGTNLTGIEETTCGP----FGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
+S ++C G L G C + W +P P CQ I C AP G + +
Sbjct: 2549 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDY 2608
Query: 276 LASFSFTSACTFICSEGTELIGKKKT--ICESSGIWSN 311
L + T+ C++G L K+ T +C+S G WSN
Sbjct: 2609 LVG----TRVTYFCNDGYRLSSKELTTAVCQSDGTWSN 2642
Score = 47.4 bits (111), Expect = 2e-05
Identities = 39/145 (26%), Positives = 54/145 (37%), Gaps = 15/145 (10%)
Query: 180 CNCDVGYYG--PQCQFVIQ--CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTG 235
C D + G P C Q CE P G+ + T F S F C +G L G
Sbjct: 3291 CQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTF---GFQVGSVVQFHCKKGHLLQG 3347
Query: 236 IEETTCGPFGNWSSPEPTCQVIQC-EPLSAPDLGIMNCSHPLASFSFTSACT--FICSEG 292
TC P WS +P C C +P + ++ P ++ C F + G
Sbjct: 3348 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3407
Query: 293 TELIGKKKTICESSGIWSNPSPICQ 317
TE +C S W+ PIC+
Sbjct: 3408 TE-----HRVCRSDNTWTGKVPICE 3427
Score = 44.7 bits (104), Expect = 1e-04
Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)
Query: 224 AFSCSEG--TNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSF 281
++ C G L G TC G WS PTC+ + C + P I N +F +
Sbjct: 3156 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCP--TPPQ--ISNGRLEGTNFDW 3211
Query: 282 TSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
+ ++ICS G EL C +G WS P C
Sbjct: 3212 GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3246
Score = 36.6 bits (83), Expect = 0.037
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 9/77 (11%)
Query: 197 CEPLEAPELGTMDCTHPLG-NFSFSSQCAFSCSEGTNLTGIEETTCGPFGN--WSSPEPT 253
CE P+ G+ +G NF FSCS G L G E C G WS+P P
Sbjct: 1142 CEDPGIPQYGSR-----IGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPR 1196
Query: 254 CQVIQCEPLSAPDLGIM 270
C V +C + + GI+
Sbjct: 1197 C-VAECGASATNNEGIL 1212
Score = 36.2 bits (82), Expect = 0.049
Identities = 16/38 (42%), Positives = 20/38 (52%)
Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
FS F C G ELIG+K +C+ + WS PIC
Sbjct: 640 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 677
Score = 36.2 bits (82), Expect = 0.049
Identities = 19/60 (31%), Positives = 27/60 (45%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
+FS S +FSC G L+ E C WS P PTC + + P I++ +P
Sbjct: 985 DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYP 1044
Score = 35.4 bits (80), Expect = 0.083
Identities = 15/41 (36%), Positives = 21/41 (51%)
Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
FS S +F C G L ++ +CE + WS+P P C L
Sbjct: 986 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL 1026
Score = 33.9 bits (76), Expect = 0.24
Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 4/48 (8%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC----GPFGNWSSPEPTCQVIQC 259
+FS S FSC E L G + TC F WS P C+V C
Sbjct: 461 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 508
Score = 33.1 bits (74), Expect = 0.41
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 6/60 (10%)
Query: 259 CEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG--IWSNPSPIC 316
CE P G S +F TF CS G L G + IC G +WS P P C
Sbjct: 1142 CEDPGIPQYG----SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1197
Score = 31.6 bits (70), Expect = 1.2
Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 3/38 (7%)
Query: 224 AFSCSEGTNLTGIEETTC--GPFGNWSSPEPTCQVIQC 259
+F C +G +L G TC GP W+ P P C + QC
Sbjct: 2035 SFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQC 2071
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 66.2 bits (160), Expect = 4e-11
Identities = 46/184 (25%), Positives = 69/184 (37%), Gaps = 30/184 (16%)
Query: 159 SCQPWSC-----------SGHGECVEIINNYTCNCDVGYYGP---QCQF----------- 193
SC P SC SG+G + ++CN GP QCQ
Sbjct: 2700 SCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMC 2759
Query: 194 -VIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEP 252
V+ C P + GNF++ + + C+ G L G C P G W P P
Sbjct: 2760 KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLP 2819
Query: 253 TCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNP 312
C +I C P +++ ++F S + C+ L+G+ C+ +G WS
Sbjct: 2820 ECIMIDCGHPGVPPNAVLSGE----KYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGS 2875
Query: 313 SPIC 316
P C
Sbjct: 2876 QPHC 2879
Score = 62.4 bits (150), Expect = 6e-10
Identities = 35/129 (27%), Positives = 53/129 (41%), Gaps = 9/129 (6%)
Query: 201 EAPELGTMDCTHP--------LGN-FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPE 251
+ P + C HP GN F+F+ FSC+ G + G + C WS P
Sbjct: 2697 QLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP 2756
Query: 252 PTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSN 311
P C+V+ C P +F++ + + C+ G L G IC+ +G W
Sbjct: 2757 PMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDK 2816
Query: 312 PSPICQKLD 320
P P C +D
Sbjct: 2817 PLPECIMID 2825
Score = 57.4 bits (137), Expect = 2e-08
Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 4/107 (3%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
N+ + + C+ G L G C NWS P+C + C +P G + +
Sbjct: 2663 NYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN-- 2720
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKS 322
F+F TF C+ G + G K C+++ WS+P P+C+ ++ S
Sbjct: 2721 --GFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCS 2765
Score = 57.4 bits (137), Expect = 2e-08
Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NF S ++C G L G EE TC G+W+ +P C+ +QC P
Sbjct: 2902 NFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQC---GNPGTTANGKVFR 2958
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
+ +F+S+ + C EG L G C ++G WS P C
Sbjct: 2959 IDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 2999
Score = 52.8 bits (125), Expect = 5e-07
Identities = 46/163 (28%), Positives = 64/163 (39%), Gaps = 18/163 (11%)
Query: 163 WSCSGHGECVEIINNYTCNCDVGYYG-----PQCQFVIQCEPLEAPELGTMDCTHPLGNF 217
W+C V + GY+ P CQ I C +AP G + T ++
Sbjct: 2490 WACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ-AISCGIPKAPTNGGILTT----DY 2544
Query: 218 SFSSQCAFSCSEGTNLTGIEETT--CGPFGNWSSPE--PTCQVIQCEPLSAPDLGIMNCS 273
++ + C++G L+ E TT C G WS+ P C VI C L P G +
Sbjct: 2545 LVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNG----N 2600
Query: 274 HPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
S+ S F C G L+G C SSG+WS C
Sbjct: 2601 KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2643
Score = 52.8 bits (125), Expect = 5e-07
Identities = 50/200 (25%), Positives = 73/200 (36%), Gaps = 31/200 (15%)
Query: 140 GKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCN------CDVGY--YGPQC 191
G W+ H A T +C GHG E +N+ CD GY +G +
Sbjct: 2870 GHWSGSQPHCSGDA---TGTCGDPGTPGHGSRQE--SNFRTKSTVRYACDTGYILHGSEE 2924
Query: 192 QFVIQCEPLEA--PELGTMDCTHP----------LGNFSFSSQCAFSCSEGTNLTGIEET 239
+ + PE + C +P + +FSS +SC EG L+G
Sbjct: 2925 RTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVR 2984
Query: 240 TCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEG--TELIG 297
C G WS P C +I C P G+ + +++C G EL G
Sbjct: 2985 QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGD----DYVVGQNVSYMCQPGYTMELNG 3040
Query: 298 KKKTICESSGIWSNPSPICQ 317
+ C +G WS P C+
Sbjct: 3041 SRIRTCTINGTWSGVMPTCR 3060
Score = 51.6 bits (122), Expect = 1e-06
Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 4/101 (3%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NF + ++ CS G L+ TC G WS P C C P G
Sbjct: 3079 NFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG----KRE 3134
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
SF + S +F C+ L+G IC++ G WS SP C
Sbjct: 3135 GKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3175
Score = 51.2 bits (121), Expect = 1e-06
Identities = 38/128 (29%), Positives = 49/128 (38%), Gaps = 9/128 (7%)
Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS 248
P+C VI C L P G T S+ S F+C G L G C G WS
Sbjct: 2583 PRC-VVISCGELPTPPNGNKIGTQT----SYGSTAIFTCDLGFMLVGSAVRECLSSGLWS 2637
Query: 249 SPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGI 308
E C C P+L I+N ++ + + C+ G LIG IC+
Sbjct: 2638 ESETRCLAGHC---GIPEL-IVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHN 2693
Query: 309 WSNPSPIC 316
WS P C
Sbjct: 2694 WSGQLPSC 2701
Score = 47.4 bits (111), Expect = 2e-05
Identities = 39/145 (26%), Positives = 54/145 (37%), Gaps = 15/145 (10%)
Query: 180 CNCDVGYYG--PQCQFVIQ--CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTG 235
C D + G P C Q CE P G+ + T F S F C +G L G
Sbjct: 3162 CQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTF---GFQVGSVVQFHCKKGHLLQG 3218
Query: 236 IEETTCGPFGNWSSPEPTCQVIQC-EPLSAPDLGIMNCSHPLASFSFTSACT--FICSEG 292
TC P WS +P C C +P + ++ P ++ C F + G
Sbjct: 3219 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3278
Query: 293 TELIGKKKTICESSGIWSNPSPICQ 317
TE +C S W+ PIC+
Sbjct: 3279 TE-----HRVCRSDNTWTGKVPICE 3298
Score = 44.7 bits (104), Expect = 1e-04
Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)
Query: 224 AFSCSEG--TNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSF 281
++ C G L G TC G WS PTC+ + C + P I N +F +
Sbjct: 3027 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCP--TPPQ--ISNGRLEGTNFDW 3082
Query: 282 TSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
+ ++ICS G EL C +G WS P C
Sbjct: 3083 GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3117
Score = 36.6 bits (83), Expect = 0.037
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 9/77 (11%)
Query: 197 CEPLEAPELGTMDCTHPLG-NFSFSSQCAFSCSEGTNLTGIEETTCGPFGN--WSSPEPT 253
CE P+ G+ +G NF FSCS G L G E C G WS+P P
Sbjct: 1078 CEDPGIPQYGSR-----IGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPR 1132
Query: 254 CQVIQCEPLSAPDLGIM 270
C V +C + + GI+
Sbjct: 1133 C-VAECGASATNNEGIL 1148
Score = 36.2 bits (82), Expect = 0.049
Identities = 16/38 (42%), Positives = 20/38 (52%)
Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
FS F C G ELIG+K +C+ + WS PIC
Sbjct: 576 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 613
Score = 36.2 bits (82), Expect = 0.049
Identities = 19/60 (31%), Positives = 27/60 (45%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
+FS S +FSC G L+ E C WS P PTC + + P I++ +P
Sbjct: 921 DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYP 980
Score = 35.4 bits (80), Expect = 0.083
Identities = 15/41 (36%), Positives = 21/41 (51%)
Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
FS S +F C G L ++ +CE + WS+P P C L
Sbjct: 922 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL 962
Score = 33.9 bits (76), Expect = 0.24
Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 4/48 (8%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC----GPFGNWSSPEPTCQVIQC 259
+FS S FSC E L G + TC F WS P C+V C
Sbjct: 397 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444
Score = 33.1 bits (74), Expect = 0.41
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 6/60 (10%)
Query: 259 CEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG--IWSNPSPIC 316
CE P G S +F TF CS G L G + IC G +WS P P C
Sbjct: 1078 CEDPGIPQYG----SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1133
Score = 31.6 bits (70), Expect = 1.2
Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 3/38 (7%)
Query: 224 AFSCSEGTNLTGIEETTC--GPFGNWSSPEPTCQVIQC 259
+F C +G +L G TC GP W+ P P C + QC
Sbjct: 1971 SFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQC 2007
Score = 30.8 bits (68), Expect = 2.0
Identities = 13/41 (31%), Positives = 17/41 (41%), Gaps = 4/41 (9%)
Query: 283 SACTFICSEGTELIGKKKTICESSG----IWSNPSPICQKL 319
S + C G L+GK +C S W P P CQ +
Sbjct: 2486 SVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI 2526
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 66.2 bits (160), Expect = 4e-11
Identities = 46/184 (25%), Positives = 69/184 (37%), Gaps = 30/184 (16%)
Query: 159 SCQPWSC-----------SGHGECVEIINNYTCNCDVGYYGP---QCQF----------- 193
SC P SC SG+G + ++CN GP QCQ
Sbjct: 2869 SCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMC 2928
Query: 194 -VIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEP 252
V+ C P + GNF++ + + C+ G L G C P G W P P
Sbjct: 2929 KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLP 2988
Query: 253 TCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNP 312
C +I C P +++ ++F S + C+ L+G+ C+ +G WS
Sbjct: 2989 ECIMIDCGHPGVPPNAVLSGE----KYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGS 3044
Query: 313 SPIC 316
P C
Sbjct: 3045 QPHC 3048
Score = 62.4 bits (150), Expect = 6e-10
Identities = 35/129 (27%), Positives = 53/129 (41%), Gaps = 9/129 (6%)
Query: 201 EAPELGTMDCTHP--------LGN-FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPE 251
+ P + C HP GN F+F+ FSC+ G + G + C WS P
Sbjct: 2866 QLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP 2925
Query: 252 PTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSN 311
P C+V+ C P +F++ + + C+ G L G IC+ +G W
Sbjct: 2926 PMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDK 2985
Query: 312 PSPICQKLD 320
P P C +D
Sbjct: 2986 PLPECIMID 2994
Score = 57.4 bits (137), Expect = 2e-08
Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 4/107 (3%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
N+ + + C+ G L G C NWS P+C + C +P G + +
Sbjct: 2832 NYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN-- 2889
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKS 322
F+F TF C+ G + G K C+++ WS+P P+C+ ++ S
Sbjct: 2890 --GFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCS 2934
Score = 57.4 bits (137), Expect = 2e-08
Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NF S ++C G L G EE TC G+W+ +P C+ +QC P
Sbjct: 3071 NFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQC---GNPGTTANGKVFR 3127
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
+ +F+S+ + C EG L G C ++G WS P C
Sbjct: 3128 IDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 3168
Score = 55.1 bits (131), Expect = 1e-07
Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS--SPEPTCQVIQCEPLSAPDLGIMNCS 273
++ + ++ FSC G + G C P G WS + P CQ+I C L P G +
Sbjct: 2714 HYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNG----N 2769
Query: 274 HPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
S+ S F C G L+G C SSG+WS C
Sbjct: 2770 KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2812
Score = 54.3 bits (129), Expect = 2e-07
Identities = 45/169 (26%), Positives = 59/169 (34%), Gaps = 29/169 (17%)
Query: 168 HGECVEIINNYTCNCDVGYYG--------------------PQCQFVIQCEPLEAPELGT 207
+G E +CD GY+G P CQ +I C L P G
Sbjct: 2711 NGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQ-IISCGELPTPPNGN 2769
Query: 208 MDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDL 267
T S+ S F+C G L G C G WS E C C P+L
Sbjct: 2770 KIGTQT----SYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHC---GIPEL 2822
Query: 268 GIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
I+N ++ + + C+ G LIG IC+ WS P C
Sbjct: 2823 -IVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSC 2870
Score = 52.8 bits (125), Expect = 5e-07
Identities = 50/200 (25%), Positives = 73/200 (36%), Gaps = 31/200 (15%)
Query: 140 GKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCN------CDVGY--YGPQC 191
G W+ H A T +C GHG E +N+ CD GY +G +
Sbjct: 3039 GHWSGSQPHCSGDA---TGTCGDPGTPGHGSRQE--SNFRTKSTVRYACDTGYILHGSEE 3093
Query: 192 QFVIQCEPLEA--PELGTMDCTHP----------LGNFSFSSQCAFSCSEGTNLTGIEET 239
+ + PE + C +P + +FSS +SC EG L+G
Sbjct: 3094 RTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVR 3153
Query: 240 TCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEG--TELIG 297
C G WS P C +I C P G+ + +++C G EL G
Sbjct: 3154 QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGD----DYVVGQNVSYMCQPGYTMELNG 3209
Query: 298 KKKTICESSGIWSNPSPICQ 317
+ C +G WS P C+
Sbjct: 3210 SRIRTCTINGTWSGVMPTCR 3229
Score = 51.6 bits (122), Expect = 1e-06
Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 4/101 (3%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NF + ++ CS G L+ TC G WS P C C P G
Sbjct: 3248 NFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG----KRE 3303
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
SF + S +F C+ L+G IC++ G WS SP C
Sbjct: 3304 GKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3344
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 10/98 (10%)
Query: 220 SSQCAFSCSEGTNLTGIEETTCGP----FGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
+S ++C G L G C + W +P P CQ I C AP G + +
Sbjct: 2589 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDY 2648
Query: 276 LASFSFTSACTFICSEGTELIGKKKT--ICESSGIWSN 311
L + T+ C++G L K+ T +C+S G WSN
Sbjct: 2649 LVG----TRVTYFCNDGYRLSSKELTTAVCQSDGTWSN 2682
Score = 47.4 bits (111), Expect = 2e-05
Identities = 39/145 (26%), Positives = 54/145 (37%), Gaps = 15/145 (10%)
Query: 180 CNCDVGYYG--PQCQFVIQ--CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTG 235
C D + G P C Q CE P G+ + T F S F C +G L G
Sbjct: 3331 CQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTF---GFQVGSVVQFHCKKGHLLQG 3387
Query: 236 IEETTCGPFGNWSSPEPTCQVIQC-EPLSAPDLGIMNCSHPLASFSFTSACT--FICSEG 292
TC P WS +P C C +P + ++ P ++ C F + G
Sbjct: 3388 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3447
Query: 293 TELIGKKKTICESSGIWSNPSPICQ 317
TE +C S W+ PIC+
Sbjct: 3448 TE-----HRVCRSDNTWTGKVPICE 3467
Score = 44.7 bits (104), Expect = 1e-04
Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)
Query: 224 AFSCSEG--TNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSF 281
++ C G L G TC G WS PTC+ + C + P I N +F +
Sbjct: 3196 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCP--TPPQ--ISNGRLEGTNFDW 3251
Query: 282 TSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
+ ++ICS G EL C +G WS P C
Sbjct: 3252 GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3286
Score = 36.6 bits (83), Expect = 0.037
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 9/77 (11%)
Query: 197 CEPLEAPELGTMDCTHPLG-NFSFSSQCAFSCSEGTNLTGIEETTCGPFGN--WSSPEPT 253
CE P+ G+ +G NF FSCS G L G E C G WS+P P
Sbjct: 1182 CEDPGIPQYGSR-----IGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPR 1236
Query: 254 CQVIQCEPLSAPDLGIM 270
C V +C + + GI+
Sbjct: 1237 C-VAECGASATNNEGIL 1252
Score = 36.2 bits (82), Expect = 0.049
Identities = 16/38 (42%), Positives = 20/38 (52%)
Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
FS F C G ELIG+K +C+ + WS PIC
Sbjct: 680 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 717
Score = 36.2 bits (82), Expect = 0.049
Identities = 19/60 (31%), Positives = 27/60 (45%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
+FS S +FSC G L+ E C WS P PTC + + P I++ +P
Sbjct: 1025 DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYP 1084
Score = 35.4 bits (80), Expect = 0.083
Identities = 15/41 (36%), Positives = 21/41 (51%)
Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
FS S +F C G L ++ +CE + WS+P P C L
Sbjct: 1026 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL 1066
Score = 33.9 bits (76), Expect = 0.24
Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 4/48 (8%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC----GPFGNWSSPEPTCQVIQC 259
+FS S FSC E L G + TC F WS P C+V C
Sbjct: 501 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 548
Score = 33.1 bits (74), Expect = 0.41
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 6/60 (10%)
Query: 259 CEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG--IWSNPSPIC 316
CE P G S +F TF CS G L G + IC G +WS P P C
Sbjct: 1182 CEDPGIPQYG----SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1237
Score = 31.6 bits (70), Expect = 1.2
Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 3/38 (7%)
Query: 224 AFSCSEGTNLTGIEETTC--GPFGNWSSPEPTCQVIQC 259
+F C +G +L G TC GP W+ P P C + QC
Sbjct: 2075 SFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQC 2111
>gi|223029384 CD209 molecule isoform 7 [Homo sapiens]
Length = 312
Score = 65.9 bits (159), Expect = 6e-11
Identities = 45/157 (28%), Positives = 64/157 (40%), Gaps = 17/157 (10%)
Query: 14 LWNIFKLWGWTMLCCDFLAHHGTDCWT------YHYSEKPMNWQRARRFCRDNYTDLVAI 67
L I++ W + L H WT Y S NW + C++ LV I
Sbjct: 143 LQEIYQELTWLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVI 202
Query: 68 QNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIWTWVGTNKSLTEEAENWGDGEPNNKKNK 125
++ E +L+ S + W+G+ + G W WV + L + W GEPNN +
Sbjct: 203 KSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNN-VGE 261
Query: 126 EDCVEIYIKRNKDAGKWNDDACHKLKAALC--YTASC 160
EDC E WNDD C+ K +C ASC
Sbjct: 262 EDCAEF------SGNGWNDDKCNLAKFWICKKSAASC 292
>gi|223029380 CD209 molecule isoform 5 [Homo sapiens]
Length = 268
Score = 65.9 bits (159), Expect = 6e-11
Identities = 45/157 (28%), Positives = 64/157 (40%), Gaps = 17/157 (10%)
Query: 14 LWNIFKLWGWTMLCCDFLAHHGTDCWT------YHYSEKPMNWQRARRFCRDNYTDLVAI 67
L I++ W + L H WT Y S NW + C++ LV I
Sbjct: 99 LQEIYQELTWLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVI 158
Query: 68 QNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIWTWVGTNKSLTEEAENWGDGEPNNKKNK 125
++ E +L+ S + W+G+ + G W WV + L + W GEPNN +
Sbjct: 159 KSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNN-VGE 217
Query: 126 EDCVEIYIKRNKDAGKWNDDACHKLKAALC--YTASC 160
EDC E WNDD C+ K +C ASC
Sbjct: 218 EDCAEF------SGNGWNDDKCNLAKFWICKKSAASC 248
>gi|4505245 mannose receptor C type 1 precursor [Homo sapiens]
Length = 1456
Score = 64.7 bits (156), Expect = 1e-10
Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 45 EKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTN 104
E+ NWQ AR+ C +LV+IQN+ E +L + S W G+ + T++ T+
Sbjct: 965 EERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTD 1024
Query: 105 KSLTEEAENWGDGEPNNKKNK-----EDCVEIYIKRNKDAGKWNDDACHKLKAALCYTAS 159
NWG G P +++ DCV I + +AGKW DD C + +C T S
Sbjct: 1025 -GRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRS 1083
Score = 62.0 bits (149), Expect = 8e-10
Identities = 44/154 (28%), Positives = 75/154 (48%), Gaps = 17/154 (11%)
Query: 39 WTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTL--PFSRSYYWIGIR-KIG 95
+ Y++S++ AR FC+ N+ DLV+IQ+++E ++L K + ++S Y+IG+ +
Sbjct: 810 YQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLISLD 869
Query: 96 GIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
+ W+ +K + +W GEPN E+CV +Y ++G WND C A +C
Sbjct: 870 KKFAWMDGSK---VDYVSWATGEPNFANEDENCVTMY----SNSGFWNDINCGYPNAFIC 922
Query: 156 Y-------TASCQPWSCSGHGECVEIINNYTCNC 182
+ P S C E N Y+ C
Sbjct: 923 QRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKC 956
Score = 54.7 bits (130), Expect = 1e-07
Identities = 36/111 (32%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
Query: 50 WQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSY---YWIGIR--KIGGIWTWVGTN 104
W +R FCR DL +I NK E + + + + S SY +W+G+ +TW +
Sbjct: 673 WFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTW---S 729
Query: 105 KSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
ENW GEPNN +N E C E+ + WND C L +C
Sbjct: 730 DGSPVSYENWAYGEPNNYQNVEYCGEL---KGDPTMSWNDINCEHLNNWIC 777
Score = 54.7 bits (130), Expect = 1e-07
Identities = 37/129 (28%), Positives = 64/129 (49%), Gaps = 14/129 (10%)
Query: 30 FLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLE-KTLPF-SRSYY 87
++ HG C+ Y S NW +A C + LV+I++ AE +L + P S++ +
Sbjct: 1238 WIPFHG-HCY-YIESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNF 1295
Query: 88 WIGI-RKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDA 146
WIG+ R + G W W+ + NW G+P+ ++N DCV ++ +G W++
Sbjct: 1296 WIGLFRNVEGTWLWINNSPV---SFVNWNTGDPSGERN--DCVALH----ASSGFWSNIH 1346
Query: 147 CHKLKAALC 155
C K +C
Sbjct: 1347 CSSYKGYIC 1355
Score = 40.8 bits (94), Expect = 0.002
Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 44 SEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGT 103
S+ + W +AR+ C+ +L++I E YL S WIG+ + W +
Sbjct: 234 SKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWS 293
Query: 104 NKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
++S NW G P+ + K CV + +N KW + C + +C
Sbjct: 294 DRSPFRYL-NWLPGSPSAEPGK-SCVSLNPGKN---AKWENLECVQKLGYIC 340
Score = 36.2 bits (82), Expect = 0.049
Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 28/130 (21%)
Query: 38 CWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGI 97
C+ H EK + + A CR DL +I E++++ L + +
Sbjct: 373 CYKIHRDEKKIQ-RDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDE---------- 421
Query: 98 WTWVGTNKSLTEEAENWGD-----------GEPNNKKNK-EDCVEIYIKRNKDAGKWNDD 145
W+G N + W D GEP+++ N+ EDCV + + KD G W D
Sbjct: 422 -LWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCV---VMKGKD-GYWADR 476
Query: 146 ACHKLKAALC 155
C +C
Sbjct: 477 GCEWPLGYIC 486
Score = 31.6 bits (70), Expect = 1.2
Identities = 32/167 (19%), Positives = 60/167 (35%), Gaps = 42/167 (25%)
Query: 40 TYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWT 99
+Y + W A +C+ + + + +I + P+S ++ W+ + +
Sbjct: 1106 SYSLMRQKFQWHEAETYCKLHNSLIASILD-----------PYSNAFAWLQM-ETSNERV 1153
Query: 100 WVGTNKSLTEEAENWGD--------GEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLK 151
W+ N +LT+ W D + K K CV + + G W C++
Sbjct: 1154 WIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLD-----GYWKTAHCNESF 1208
Query: 152 AALCYTA----SCQPWSCSG-------------HGECVEIINNYTCN 181
LC + + +P G HG C I ++YT N
Sbjct: 1209 YFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRN 1255
>gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens]
Length = 1456
Score = 64.7 bits (156), Expect = 1e-10
Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 45 EKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTN 104
E+ NWQ AR+ C +LV+IQN+ E +L + S W G+ + T++ T+
Sbjct: 965 EERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTD 1024
Query: 105 KSLTEEAENWGDGEPNNKKNK-----EDCVEIYIKRNKDAGKWNDDACHKLKAALCYTAS 159
NWG G P +++ DCV I + +AGKW DD C + +C T S
Sbjct: 1025 -GRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRS 1083
Score = 62.0 bits (149), Expect = 8e-10
Identities = 44/154 (28%), Positives = 75/154 (48%), Gaps = 17/154 (11%)
Query: 39 WTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTL--PFSRSYYWIGIR-KIG 95
+ Y++S++ AR FC+ N+ DLV+IQ+++E ++L K + ++S Y+IG+ +
Sbjct: 810 YQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLISLD 869
Query: 96 GIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
+ W+ +K + +W GEPN E+CV +Y ++G WND C A +C
Sbjct: 870 KKFAWMDGSK---VDYVSWATGEPNFANEDENCVTMY----SNSGFWNDINCGYPNAFIC 922
Query: 156 Y-------TASCQPWSCSGHGECVEIINNYTCNC 182
+ P S C E N Y+ C
Sbjct: 923 QRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKC 956
Score = 54.7 bits (130), Expect = 1e-07
Identities = 36/111 (32%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
Query: 50 WQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSY---YWIGIR--KIGGIWTWVGTN 104
W +R FCR DL +I NK E + + + + S SY +W+G+ +TW +
Sbjct: 673 WFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTW---S 729
Query: 105 KSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
ENW GEPNN +N E C E+ + WND C L +C
Sbjct: 730 DGSPVSYENWAYGEPNNYQNVEYCGEL---KGDPTMSWNDINCEHLNNWIC 777
Score = 54.7 bits (130), Expect = 1e-07
Identities = 37/129 (28%), Positives = 64/129 (49%), Gaps = 14/129 (10%)
Query: 30 FLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLE-KTLPF-SRSYY 87
++ HG C+ Y S NW +A C + LV+I++ AE +L + P S++ +
Sbjct: 1238 WIPFHG-HCY-YIESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNF 1295
Query: 88 WIGI-RKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDA 146
WIG+ R + G W W+ + NW G+P+ ++N DCV ++ +G W++
Sbjct: 1296 WIGLFRNVEGTWLWINNSPV---SFVNWNTGDPSGERN--DCVALH----ASSGFWSNIH 1346
Query: 147 CHKLKAALC 155
C K +C
Sbjct: 1347 CSSYKGYIC 1355
Score = 40.8 bits (94), Expect = 0.002
Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 44 SEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGT 103
S+ + W +AR+ C+ +L++I E YL S WIG+ + W +
Sbjct: 234 SKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWS 293
Query: 104 NKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC 155
++S NW G P+ + K CV + +N KW + C + +C
Sbjct: 294 DRSPFRYL-NWLPGSPSAEPGK-SCVSLNPGKN---AKWENLECVQKLGYIC 340
Score = 36.6 bits (83), Expect = 0.037
Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 28/130 (21%)
Query: 38 CWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGI 97
C+ H EK + + A CR +DL +I E +++ L + +
Sbjct: 373 CYKIHRDEKKIQ-RDALTTCRKEGSDLASIHTIEEFDFIISQLGYEPNDE---------- 421
Query: 98 WTWVGTNKSLTEEAENWGD-----------GEPNNKKNK-EDCVEIYIKRNKDAGKWNDD 145
W+G N + W D GEP+++ N+ EDCV + + KD G W D
Sbjct: 422 -LWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCV---VMKGKD-GYWADR 476
Query: 146 ACHKLKAALC 155
C +C
Sbjct: 477 GCEWPLGYIC 486
Score = 31.6 bits (70), Expect = 1.2
Identities = 32/167 (19%), Positives = 60/167 (35%), Gaps = 42/167 (25%)
Query: 40 TYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWT 99
+Y + W A +C+ + + + +I + P+S ++ W+ + +
Sbjct: 1106 SYSLMRQKFQWHEAETYCKLHNSLIASILD-----------PYSNAFAWLQM-ETSNERV 1153
Query: 100 WVGTNKSLTEEAENWGD--------GEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLK 151
W+ N +LT+ W D + K K CV + + G W C++
Sbjct: 1154 WIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLD-----GYWKTAHCNESF 1208
Query: 152 AALCYTA----SCQPWSCSG-------------HGECVEIINNYTCN 181
LC + + +P G HG C I ++YT N
Sbjct: 1209 YFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRN 1255
>gi|20149533 Fc fragment of IgE, low affinity II, receptor for
(CD23A) [Homo sapiens]
Length = 321
Score = 63.9 bits (154), Expect = 2e-10
Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 14/134 (10%)
Query: 41 YHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIW 98
Y++ + W AR C D LV+I + E ++L K + S WIG+R + G +
Sbjct: 175 YYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGS--WIGLRNLDLKGEF 232
Query: 99 TWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDAC-HKLKAALC-Y 156
WV + + NW GEP ++ EDCV + + +G+WND C KL A +C
Sbjct: 233 IWVDGSH---VDYSNWAPGEPTSRSQGEDCVMM-----RGSGRWNDAFCDRKLGAWVCDR 284
Query: 157 TASCQPWSCSGHGE 170
A+C P + G E
Sbjct: 285 LATCTPPASEGSAE 298
>gi|223029517 CD209 molecule isoform 8 [Homo sapiens]
Length = 243
Score = 63.5 bits (153), Expect = 3e-10
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 11/124 (8%)
Query: 41 YHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIW 98
Y S NW + C++ LV I++ E +L+ S + W+G+ + G W
Sbjct: 107 YFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTW 166
Query: 99 TWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC--Y 156
WV + L + W GEPNN +EDC E WNDD C+ K +C
Sbjct: 167 QWVDGSPLLPSFKQYWNRGEPNN-VGEEDCAEF------SGNGWNDDKCNLAKFWICKKS 219
Query: 157 TASC 160
ASC
Sbjct: 220 AASC 223
>gi|223029386 CD209 molecule isoform 3 [Homo sapiens]
Length = 380
Score = 63.5 bits (153), Expect = 3e-10
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 11/124 (8%)
Query: 41 YHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIW 98
Y S NW + C++ LV I++ E +L+ S + W+G+ + G W
Sbjct: 244 YFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTW 303
Query: 99 TWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC--Y 156
WV + L + W GEPNN +EDC E WNDD C+ K +C
Sbjct: 304 QWVDGSPLLPSFKQYWNRGEPNN-VGEEDCAEF------SGNGWNDDKCNLAKFWICKKS 356
Query: 157 TASC 160
ASC
Sbjct: 357 AASC 360
>gi|223029382 CD209 molecule isoform 6 [Homo sapiens]
Length = 360
Score = 63.5 bits (153), Expect = 3e-10
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 11/124 (8%)
Query: 41 YHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIW 98
Y S NW + C++ LV I++ E +L+ S + W+G+ + G W
Sbjct: 224 YFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTW 283
Query: 99 TWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC--Y 156
WV + L + W GEPNN +EDC E WNDD C+ K +C
Sbjct: 284 QWVDGSPLLPSFKQYWNRGEPNN-VGEEDCAEF------SGNGWNDDKCNLAKFWICKKS 336
Query: 157 TASC 160
ASC
Sbjct: 337 AASC 340
>gi|10863957 CD209 molecule isoform 1 [Homo sapiens]
Length = 404
Score = 63.5 bits (153), Expect = 3e-10
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 11/124 (8%)
Query: 41 YHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIG--GIW 98
Y S NW + C++ LV I++ E +L+ S + W+G+ + G W
Sbjct: 268 YFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTW 327
Query: 99 TWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALC--Y 156
WV + L + W GEPNN +EDC E WNDD C+ K +C
Sbjct: 328 QWVDGSPLLPSFKQYWNRGEPNN-VGEEDCAEF------SGNGWNDDKCNLAKFWICKKS 380
Query: 157 TASC 160
ASC
Sbjct: 381 AASC 384
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 63.5 bits (153), Expect = 3e-10
Identities = 40/152 (26%), Positives = 61/152 (40%), Gaps = 14/152 (9%)
Query: 178 YTCNCDVGYYGPQCQFVIQCEPL--EAPELGTMDCTHPLGN----------FSFSSQCAF 225
Y CN G + +Q + P + C HP GN F+ + F
Sbjct: 2705 YQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHP-GNPAHGFTNGSEFNLNDVVNF 2763
Query: 226 SCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL-ASFSFTSA 284
+C+ G L G+ C G WSSP PTC+V+ C + I + SF + +
Sbjct: 2764 TCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMS 2823
Query: 285 CTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
+ C +G L+G C ++G+W P C
Sbjct: 2824 ILYHCKKGFYLLGSSALTCMANGLWDRSLPKC 2855
Score = 59.3 bits (142), Expect = 5e-09
Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
+F S FSC G L G E TC G+WS +P C+ + C P G++ S
Sbjct: 2936 DFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDG 2995
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
+ F+S+ + C EG + G C ++G W+ +P C
Sbjct: 2996 IL---FSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDC 3033
Score = 57.4 bits (137), Expect = 2e-08
Identities = 32/106 (30%), Positives = 43/106 (40%), Gaps = 4/106 (3%)
Query: 217 FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL 276
FS+ + C+ G L G C WS P C I C P G N S
Sbjct: 2697 FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSE-- 2754
Query: 277 ASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKS 322
F+ F C+ G L G + C S+G WS+P P C+ ++ S
Sbjct: 2755 --FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCS 2798
Score = 53.9 bits (128), Expect = 2e-07
Identities = 38/135 (28%), Positives = 56/135 (41%), Gaps = 11/135 (8%)
Query: 183 DVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFS-FSSQCAFSCSEGTNLTGIEETTC 241
++G P C+ VI C L P G + +G + + + F+C+ G L G C
Sbjct: 2610 NIGDERPSCR-VISCGSLSFPPNG-----NKIGTLTVYGATAIFTCNTGYTLVGSHVREC 2663
Query: 242 GPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKT 301
G WS E C C +PD I+N FS+ + C+ G L+G
Sbjct: 2664 LANGLWSGSETRCLAGHC---GSPD-PIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVR 2719
Query: 302 ICESSGIWSNPSPIC 316
IC WS +P+C
Sbjct: 2720 ICLQDHKWSGQTPVC 2734
Score = 53.9 bits (128), Expect = 2e-07
Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 13/152 (8%)
Query: 169 GECVEIINNYTCNCDV-GYYGPQ---CQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCA 224
G +E + + T C G + P C+ V+ C + GT++ + +F + S +
Sbjct: 3067 GYVMEAVTSATIRCTKDGRWNPSKPVCKAVL-CPQPPPVQNGTVEGS----DFRWGSSIS 3121
Query: 225 FSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSA 284
+SC +G L+ +C G W P C + C P G ++ SF++ S
Sbjct: 3122 YSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGK----SFTYKSE 3177
Query: 285 CTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
F C L+G + +C++ G WS P C
Sbjct: 3178 VFFQCKSPFILVGSSRRVCQADGTWSGIQPTC 3209
Score = 52.8 bits (125), Expect = 5e-07
Identities = 36/128 (28%), Positives = 52/128 (40%), Gaps = 12/128 (9%)
Query: 197 CEPLEAPELGTMDCTHPLGNF------SFSSQCAFSCSEGTNLTGIEETTCGPFGNWS-- 248
C+P+ P + H + + +Q SCS G L G C G W+
Sbjct: 2553 CKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIG 2612
Query: 249 SPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGI 308
P+C+VI C LS P G N L + T+ F C+ G L+G C ++G+
Sbjct: 2613 DERPSCRVISCGSLSFPPNG--NKIGTLTVYGATA--IFTCNTGYTLVGSHVRECLANGL 2668
Query: 309 WSNPSPIC 316
WS C
Sbjct: 2669 WSGSETRC 2676
Score = 48.9 bits (115), Expect = 7e-06
Identities = 35/123 (28%), Positives = 50/123 (40%), Gaps = 20/123 (16%)
Query: 211 THPLGNFSFSSQCA--------FSCSEGTNLTGIEETTC--GPFG--NWSSPEPTCQVIQ 258
THPL N ++ A + C G + G TC P G W S P CQ +
Sbjct: 2436 THPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVS 2495
Query: 259 CEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKK--TICESSGIWSNPS--P 314
C +P N S F+ S + C EG +L ++ +C+ G+WSN P
Sbjct: 2496 CGIPESPG----NGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPP 2551
Query: 315 ICQ 317
C+
Sbjct: 2552 TCK 2554
Score = 47.4 bits (111), Expect = 2e-05
Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 6/101 (5%)
Query: 219 FSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLAS 278
FSS ++C EG +G+ C G W+ P C +I C GI +
Sbjct: 2998 FSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGT----D 3053
Query: 279 FSFTSACTFICSEG--TELIGKKKTICESSGIWSNPSPICQ 317
F+F ++ C+ G E + C G W+ P+C+
Sbjct: 3054 FTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCK 3094
Score = 45.8 bits (107), Expect = 6e-05
Identities = 24/101 (23%), Positives = 36/101 (35%), Gaps = 4/101 (3%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
+F + + C +G L G TC G W P C I C P ++
Sbjct: 2817 SFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGE-- 2874
Query: 276 LASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
F++ + + C LIG +C+ WS P C
Sbjct: 2875 --LFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHC 2913
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/104 (25%), Positives = 39/104 (37%), Gaps = 7/104 (6%)
Query: 217 FSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQ---CEPLSAPDLGIMNCS 273
F++ + +SC +L G + C +WS P C C P G S
Sbjct: 2876 FTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHG----S 2931
Query: 274 HPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQ 317
F S F C G +L G + C +G WS P+C+
Sbjct: 2932 RLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCE 2975
Score = 34.3 bits (77), Expect = 0.19
Identities = 27/122 (22%), Positives = 45/122 (36%), Gaps = 7/122 (5%)
Query: 197 CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQV 256
C P G + + + S F C +G ++ G TC WS + C
Sbjct: 3217 CPDPGTPHFGIQNSSR---GYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIP 3273
Query: 257 IQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELI-GKKKTICESSGIWSNPSPI 315
C P + + L +F +T + C G L G + C++ W+ SP+
Sbjct: 3274 HACRQPETPAHADVR-AIDLPTFGYT--LVYTCHPGFFLAGGSEHRTCKADMKWTGKSPV 3330
Query: 316 CQ 317
C+
Sbjct: 3331 CK 3332
Score = 32.0 bits (71), Expect = 0.92
Identities = 13/40 (32%), Positives = 19/40 (47%)
Query: 277 ASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPIC 316
+SF TF C EL+G++ C+ + WS P C
Sbjct: 542 SSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
Score = 31.2 bits (69), Expect = 1.6
Identities = 15/51 (29%), Positives = 21/51 (41%)
Query: 279 FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEG 329
F S TF C G L + +CE + W++ P C L + K G
Sbjct: 890 FGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSG 940
Score = 30.0 bits (66), Expect = 3.5
Identities = 13/43 (30%), Positives = 18/43 (41%)
Query: 215 GNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVI 257
G+F S FSC G L+ E C W+ P+C +
Sbjct: 888 GDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL 930
Score = 29.6 bits (65), Expect = 4.6
Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 3/46 (6%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGN--WSSPEPTCQVIQC 259
+F FSC G L G + TC G WS+P P C V +C
Sbjct: 1061 HFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC-VAEC 1105
>gi|33667103 C-type lectin, superfamily member 14 isoform 1 [Homo
sapiens]
Length = 316
Score = 63.2 bits (152), Expect = 4e-10
Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 16/129 (12%)
Query: 27 CCDF-LAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRS 85
CC H C Y +S M+W A ++C+ LV I ++ E +++K L +
Sbjct: 180 CCPVNWVEHQDSC--YWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYL--GSA 235
Query: 86 YYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNK-----EDCVEIYIKRNKDAG 140
Y W+G+ G W WV T +NW G+P++ + EDC + G
Sbjct: 236 YTWMGLSDPEGAWKWVDGTDYAT-GFQNWKPGQPDDWQGHGLGGGEDCAHFH-----PDG 289
Query: 141 KWNDDACHK 149
+WNDD C +
Sbjct: 290 RWNDDVCQR 298
>gi|53832016 C-type lectin, superfamily member 14 isoform 2 [Homo
sapiens]
Length = 292
Score = 63.2 bits (152), Expect = 4e-10
Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 16/129 (12%)
Query: 27 CCDF-LAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRS 85
CC H C Y +S M+W A ++C+ LV I ++ E +++K L +
Sbjct: 156 CCPVNWVEHQDSC--YWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYL--GSA 211
Query: 86 YYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNK-----EDCVEIYIKRNKDAG 140
Y W+G+ G W WV T +NW G+P++ + EDC + G
Sbjct: 212 YTWMGLSDPEGAWKWVDGTDYAT-GFQNWKPGQPDDWQGHGLGGGEDCAHFH-----PDG 265
Query: 141 KWNDDACHK 149
+WNDD C +
Sbjct: 266 RWNDDVCQR 274
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 61.6 bits (148), Expect = 1e-09
Identities = 44/138 (31%), Positives = 59/138 (42%), Gaps = 17/138 (12%)
Query: 197 CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPT 253
C P P G + H + F S +SC+EG L G TTC GN W P
Sbjct: 1907 CGPPPEPFNGMV---HINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPI 1963
Query: 254 CQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS- 306
C++I CEP G S+ SF + T+ C G EL+G++ C S
Sbjct: 1964 CEIISCEPPPTISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKD 2022
Query: 307 ---GIWSNPSPICQKLDK 321
G+WS+P P C +K
Sbjct: 2023 DQVGVWSSPPPRCISTNK 2040
Score = 58.9 bits (141), Expect = 7e-09
Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 9/109 (8%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NFS + +SC G +L G C P G+WS PTC+V C+ +G +
Sbjct: 315 NFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF----MGQLLNGRV 370
Query: 276 L--ASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
L + + F+C EG +L G + C +G +W++ P+C+++
Sbjct: 371 LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Score = 58.9 bits (141), Expect = 7e-09
Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 9/109 (8%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NFS + +SC G +L G C P G+WS PTC+V C+ +G +
Sbjct: 765 NFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF----MGQLLNGRV 820
Query: 276 L--ASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
L + + F+C EG +L G + C +G +W++ P+C+++
Sbjct: 821 LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 869
Score = 58.9 bits (141), Expect = 7e-09
Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 9/109 (8%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NFS + +SC G +L G C P G+WS PTC+V C+ +G +
Sbjct: 1215 NFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF----MGQLLNGRV 1270
Query: 276 L--ASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
L + + F+C EG +L G + C +G +W++ P+C+++
Sbjct: 1271 LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 1319
Score = 58.2 bits (139), Expect = 1e-08
Identities = 41/155 (26%), Positives = 71/155 (45%), Gaps = 16/155 (10%)
Query: 174 IINNYTCNCDV-GYYGPQCQFVIQ-CEPLEAPEL--GTMDCTHPLGNFSFSSQCAFSCSE 229
++ ++T C G +GP+ + C+P PE+ G +H NFS + +SC
Sbjct: 2075 MVGSHTVQCQTNGRWGPKLPHCSRVCQP--PPEILHGEHTLSHQ-DNFSPGQEVFYSCEP 2131
Query: 230 GTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL--ASFSFTSACTF 287
+L G C P G+WS P C V C+ LG + L + + +F
Sbjct: 2132 SYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDF----LGQLPHGRVLLPLNLQLGAKVSF 2187
Query: 288 ICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
+C EG L G+ + C +G +W++ P+C+++
Sbjct: 2188 VCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQI 2222
Score = 55.8 bits (133), Expect = 6e-08
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 16/138 (11%)
Query: 189 PQCQFVIQCEPLEAPEL--GTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN 246
P C V C+P PE+ G +H NFS + +SC G +L G C P G+
Sbjct: 1641 PSCSRV--CQP--PPEILHGEHTPSHQ-DNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD 1695
Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPL--ASFSFTSACTFICSEGTELIGKKKTICE 304
WS P C V C+ LG + L + + +F+C EG L G + C
Sbjct: 1696 WSPEAPRCAVKSCDDF----LGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCV 1751
Query: 305 SSG---IWSNPSPICQKL 319
G +W+N P+C+ +
Sbjct: 1752 LVGMRSLWNNSVPVCEHI 1769
Score = 53.5 bits (127), Expect = 3e-07
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)
Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
H + F SQ +SC++G L G TC G+ W + P C I C P + +
Sbjct: 116 HVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNG 175
Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
++ + +F + S T+ C+ G+ EL+G+ C S+ GIWS P+P C
Sbjct: 176 DFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 232
Score = 51.2 bits (121), Expect = 1e-06
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)
Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
H + + S+ +SC+ G L G C GN WS+ P CQ I C P + +
Sbjct: 566 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANG 625
Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
++ + +F + S T+ C+ G+ EL+G+ C S+ GIWS P+P C
Sbjct: 626 DFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 51.2 bits (121), Expect = 1e-06
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)
Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
H + + S+ +SC+ G L G C GN WS+ P CQ I C P + +
Sbjct: 1016 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANG 1075
Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
++ + +F + S T+ C+ G+ EL+G+ C S+ GIWS P+P C
Sbjct: 1076 DFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 1132
Score = 50.4 bits (119), Expect = 2e-06
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)
Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
H + + S+ +SC+ G L G C GN WS+ P CQ I C P + +
Sbjct: 1466 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANG 1525
Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
++ + +F + S T+ C+ G+ EL+G+ C S+ GIWS P+P C
Sbjct: 1526 DFISTNR--ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 1582
Score = 50.1 bits (118), Expect = 3e-06
Identities = 44/172 (25%), Positives = 66/172 (38%), Gaps = 21/172 (12%)
Query: 163 WSCSGH---GECVEIINNYTCNCDVGYYG--------PQCQFVIQCEPLEAPE-LGTMDC 210
++C H G +I T C +G P+C+ ++ + PE
Sbjct: 1798 YTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASP 1857
Query: 211 THPLGNFSF--SSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLG 268
T P+ +F F + + C G + +C WSS E C+ C P P G
Sbjct: 1858 TIPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNG 1916
Query: 269 IMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQ 317
++ H F S + C+EG LIG T C SG W +PIC+
Sbjct: 1917 MV---HINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE 1965
Score = 48.9 bits (115), Expect = 7e-06
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 16/131 (12%)
Query: 213 PLGNFSFSSQCAFSCSEGT------NLTGIEETTC--GPFGN--WSSPEPTCQVIQCEPL 262
P G+ + + +++C NL G C P GN WSSP P C++ P
Sbjct: 2239 PFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCEL--SVPA 2296
Query: 263 SAPDLGIMNCSHPLAS----FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQK 318
+ P + H + + ++IC G L+GK C GIWS C++
Sbjct: 2297 ACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKE 2356
Query: 319 LDKSFSMIKEG 329
++ SF + G
Sbjct: 2357 VNCSFPLFMNG 2367
Score = 48.1 bits (113), Expect = 1e-05
Identities = 35/114 (30%), Positives = 48/114 (42%), Gaps = 14/114 (12%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGNWSSPEPTCQVIQCEPLSAPDLGIMNC 272
N ++ F C EG L G + C G W+S P C+ I C G +
Sbjct: 1275 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG-RHT 1333
Query: 273 SHPLASFSFTSACTFICS----EGT--ELIGKKKTICES----SGIWSNPSPIC 316
PL F F A + C GT +LIG+ C S +G+WS+P+P C
Sbjct: 1334 GKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 1387
Score = 46.6 bits (109), Expect = 4e-05
Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 14/114 (12%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGNWSSPEPTCQVIQCEPLSAPDLGIMNC 272
N ++ F C EG L G + C G W+S P C+ I C G +
Sbjct: 375 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG-RHT 433
Query: 273 SHPLASFSFTSACTFICS----EGT--ELIGKKKTICES----SGIWSNPSPIC 316
PL F F + C GT +LIG+ C S +G+WS+P+P C
Sbjct: 434 GKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487
Score = 46.6 bits (109), Expect = 4e-05
Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 14/114 (12%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGNWSSPEPTCQVIQCEPLSAPDLGIMNC 272
N ++ F C EG L G + C G W+S P C+ I C G +
Sbjct: 825 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG-RHT 883
Query: 273 SHPLASFSFTSACTFICS----EGT--ELIGKKKTICES----SGIWSNPSPIC 316
PL F F + C GT +LIG+ C S +G+WS+P+P C
Sbjct: 884 GKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 937
Score = 44.3 bits (103), Expect = 2e-04
Identities = 37/144 (25%), Positives = 55/144 (38%), Gaps = 31/144 (21%)
Query: 201 EAPELGTMDCTHPLG-----------NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGN 246
EAP C LG N ++ +F C EG L G + C G
Sbjct: 1699 EAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSL 1758
Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSH---PLASFSFTSACTFICSEGTE------LIG 297
W++ P C+ I C A I+N H P + ++ C + LIG
Sbjct: 1759 WNNSVPVCEHIFCPNPPA----ILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIG 1814
Query: 298 KKKTICES----SGIWSNPSPICQ 317
+ C S +G+WS+P+P C+
Sbjct: 1815 ESTIRCTSDPHGNGVWSSPAPRCE 1838
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
WSSP+ C+ C+ P G++ H + S + C+ G LIG C S
Sbjct: 542 WSSPKDVCKRKSCKTPPDPVNGMV---HVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598
Query: 307 G---IWSNPSPICQKL 319
G WS PICQ++
Sbjct: 599 GNAAHWSTKPPICQRI 614
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
WSSP+ C+ C+ P G++ H + S + C+ G LIG C S
Sbjct: 992 WSSPKDVCKRKSCKTPPDPVNGMV---HVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 307 G---IWSNPSPICQKL 319
G WS PICQ++
Sbjct: 1049 GNAAHWSTKPPICQRI 1064
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
WSSP+ C+ C+ P G++ H + S + C+ G LIG C S
Sbjct: 1442 WSSPKDVCKRKSCKTPPDPVNGMV---HVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1498
Query: 307 G---IWSNPSPICQKL 319
G WS PICQ++
Sbjct: 1499 GNTAHWSTKPPICQRI 1514
Score = 42.4 bits (98), Expect = 7e-04
Identities = 37/155 (23%), Positives = 62/155 (40%), Gaps = 17/155 (10%)
Query: 189 PQCQFVIQCEPLEAPELGTMDC-THPLGNFSFSSQCAFSCSEGTN------LTGIEETTC 241
P C+ +I CEP P + D ++ +F + + C G + L G C
Sbjct: 1962 PICE-IISCEP--PPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYC 2018
Query: 242 ----GPFGNWSSPEPTCQVIQCEPLSAPDL-GIMNCSHPLASFSFTSACTFICSEGTELI 296
G WSSP P C I +AP++ + + F+ T F C G ++
Sbjct: 2019 TSKDDQVGVWSSPPPRC--ISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMV 2076
Query: 297 GKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDY 331
G C+++G W P C ++ + I G++
Sbjct: 2077 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEH 2111
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
W+ + C+ C P G++ H + F S + C++G LIG C S
Sbjct: 92 WTGAKDRCRRKSCRNPPDPVNGMV---HVIKGIQFGSQIKYSCTKGYRLIGSSSATCIIS 148
Query: 307 G---IWSNPSPICQKL 319
G IW N +PIC ++
Sbjct: 149 GDTVIWDNETPICDRI 164
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 13/129 (10%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
NF + S + C+ G+ + E P G WS P P C + +C P +
Sbjct: 1534 NFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 1593
Query: 265 PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFS 324
+ GI+ S + FS F C G + G ++ C++ W P C ++ +
Sbjct: 1594 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 1651
Query: 325 MIKEGDYNP 333
I G++ P
Sbjct: 1652 EILHGEHTP 1660
Score = 38.9 bits (89), Expect = 0.008
Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 13/115 (11%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
NF + S + C+ G+ + E P G WS P P C + +C P +
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 265 PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
+ GI+ S + FS F C G + G ++ C++ W P C ++
Sbjct: 244 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296
Score = 38.9 bits (89), Expect = 0.008
Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 13/115 (11%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
NF + S + C+ G+ + E P G WS P P C + +C P +
Sbjct: 634 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 693
Query: 265 PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
+ GI+ S + FS F C G + G ++ C++ W P C ++
Sbjct: 694 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746
Score = 38.9 bits (89), Expect = 0.008
Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 13/115 (11%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
NF + S + C+ G+ + E P G WS P P C + +C P +
Sbjct: 1084 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 1143
Query: 265 PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
+ GI+ S + FS F C G + G ++ C++ W P C ++
Sbjct: 1144 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 1196
Score = 36.2 bits (82), Expect = 0.049
Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 213 PLGNFSFSSQCAFSCS----EGTNLTGIEETTC----GPFGN--WSSPEPTCQVI-QCEP 261
PL F F ++C GT+ I E+T P GN WSSP P C ++ C+
Sbjct: 436 PLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ- 494
Query: 262 LSAPD---LGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTI-CESSGIWSNPSPICQ 317
APD + + F ++ + C E G+ +I C + +WS+P +C+
Sbjct: 495 --APDHFLFAKLKTQTNASDFPIGTSLKYECR--PEYYGRPFSITCLDNLVWSSPKDVCK 550
Query: 318 K 318
+
Sbjct: 551 R 551
Score = 36.2 bits (82), Expect = 0.049
Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 213 PLGNFSFSSQCAFSCS----EGTNLTGIEETTC----GPFGN--WSSPEPTCQVI-QCEP 261
PL F F ++C GT+ I E+T P GN WSSP P C ++ C+
Sbjct: 886 PLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ- 944
Query: 262 LSAPD---LGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTI-CESSGIWSNPSPICQ 317
APD + + F ++ + C E G+ +I C + +WS+P +C+
Sbjct: 945 --APDHFLFAKLKTQTNASDFPIGTSLKYECR--PEYYGRPFSITCLDNLVWSSPKDVCK 1000
Query: 318 K 318
+
Sbjct: 1001 R 1001
Score = 36.2 bits (82), Expect = 0.049
Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 213 PLGNFSFSSQCAFSCS----EGTNLTGIEETTC----GPFGN--WSSPEPTCQVI-QCEP 261
PL F F ++C GT+ I E+T P GN WSSP P C ++ C+
Sbjct: 1336 PLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ- 1394
Query: 262 LSAPD---LGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTI-CESSGIWSNPSPICQ 317
APD + + F ++ + C E G+ +I C + +WS+P +C+
Sbjct: 1395 --APDHFLFAKLKTQTNASDFPIGTSLKYECR--PEYYGRPFSITCLDNLVWSSPKDVCK 1450
Query: 318 K 318
+
Sbjct: 1451 R 1451
Score = 30.8 bits (68), Expect = 2.0
Identities = 29/142 (20%), Positives = 49/142 (34%), Gaps = 12/142 (8%)
Query: 224 AFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCE-PLSAPDLGIMNCSHPLASFSFT 282
++ C G L G C G WS + C+ + C PL GI + +
Sbjct: 2324 SYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMN--GISKELEMKKVYHYG 2381
Query: 283 SACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMV 342
T C +G L G + C++ W P C ++ FI + +
Sbjct: 2382 DYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSGTIFFILLII-- 2439
Query: 343 TAFSGLAFIIWLARRLKKGKKS 364
F+ W+ + +KG +
Sbjct: 2440 -------FLSWIILKHRKGNNA 2454
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 61.6 bits (148), Expect = 1e-09
Identities = 44/138 (31%), Positives = 59/138 (42%), Gaps = 17/138 (12%)
Query: 197 CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPT 253
C P P G + H + F S +SC+EG L G TTC GN W P
Sbjct: 1457 CGPPPEPFNGMV---HINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPI 1513
Query: 254 CQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS- 306
C++I CEP G S+ SF + T+ C G EL+G++ C S
Sbjct: 1514 CEIISCEPPPTISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKD 1572
Query: 307 ---GIWSNPSPICQKLDK 321
G+WS+P P C +K
Sbjct: 1573 DQVGVWSSPPPRCISTNK 1590
Score = 58.9 bits (141), Expect = 7e-09
Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 9/109 (8%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NFS + +SC G +L G C P G+WS PTC+V C+ +G +
Sbjct: 315 NFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF----MGQLLNGRV 370
Query: 276 L--ASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
L + + F+C EG +L G + C +G +W++ P+C+++
Sbjct: 371 LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Score = 58.9 bits (141), Expect = 7e-09
Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 9/109 (8%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHP 275
NFS + +SC G +L G C P G+WS PTC+V C+ +G +
Sbjct: 765 NFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF----MGQLLNGRV 820
Query: 276 L--ASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
L + + F+C EG +L G + C +G +W++ P+C+++
Sbjct: 821 LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 869
Score = 58.2 bits (139), Expect = 1e-08
Identities = 41/155 (26%), Positives = 71/155 (45%), Gaps = 16/155 (10%)
Query: 174 IINNYTCNCDV-GYYGPQCQFVIQ-CEPLEAPEL--GTMDCTHPLGNFSFSSQCAFSCSE 229
++ ++T C G +GP+ + C+P PE+ G +H NFS + +SC
Sbjct: 1625 MVGSHTVQCQTNGRWGPKLPHCSRVCQP--PPEILHGEHTLSHQ-DNFSPGQEVFYSCEP 1681
Query: 230 GTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL--ASFSFTSACTF 287
+L G C P G+WS P C V C+ LG + L + + +F
Sbjct: 1682 SYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDF----LGQLPHGRVLLPLNLQLGAKVSF 1737
Query: 288 ICSEGTELIGKKKTICESSG---IWSNPSPICQKL 319
+C EG L G+ + C +G +W++ P+C+++
Sbjct: 1738 VCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQI 1772
Score = 55.8 bits (133), Expect = 6e-08
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 16/138 (11%)
Query: 189 PQCQFVIQCEPLEAPEL--GTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN 246
P C V C+P PE+ G +H NFS + +SC G +L G C P G+
Sbjct: 1191 PSCSRV--CQP--PPEILHGEHTPSHQ-DNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD 1245
Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPL--ASFSFTSACTFICSEGTELIGKKKTICE 304
WS P C V C+ LG + L + + +F+C EG L G + C
Sbjct: 1246 WSPEAPRCAVKSCDDF----LGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCV 1301
Query: 305 SSG---IWSNPSPICQKL 319
G +W+N P+C+ +
Sbjct: 1302 LVGMRSLWNNSVPVCEHI 1319
Score = 53.5 bits (127), Expect = 3e-07
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)
Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
H + F SQ +SC++G L G TC G+ W + P C I C P + +
Sbjct: 116 HVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNG 175
Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
++ + +F + S T+ C+ G+ EL+G+ C S+ GIWS P+P C
Sbjct: 176 DFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 232
Score = 51.2 bits (121), Expect = 1e-06
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)
Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
H + + S+ +SC+ G L G C GN WS+ P CQ I C P + +
Sbjct: 566 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANG 625
Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
++ + +F + S T+ C+ G+ EL+G+ C S+ GIWS P+P C
Sbjct: 626 DFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 50.4 bits (119), Expect = 2e-06
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 16/119 (13%)
Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
H + + S+ +SC+ G L G C GN WS+ P CQ I C P + +
Sbjct: 1016 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANG 1075
Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
++ + +F + S T+ C+ G+ EL+G+ C S+ GIWS P+P C
Sbjct: 1076 DFISTNR--ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 1132
Score = 50.1 bits (118), Expect = 3e-06
Identities = 44/172 (25%), Positives = 66/172 (38%), Gaps = 21/172 (12%)
Query: 163 WSCSGH---GECVEIINNYTCNCDVGYYG--------PQCQFVIQCEPLEAPE-LGTMDC 210
++C H G +I T C +G P+C+ ++ + PE
Sbjct: 1348 YTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASP 1407
Query: 211 THPLGNFSF--SSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLG 268
T P+ +F F + + C G + +C WSS E C+ C P P G
Sbjct: 1408 TIPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNG 1466
Query: 269 IMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQ 317
++ H F S + C+EG LIG T C SG W +PIC+
Sbjct: 1467 MV---HINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE 1515
Score = 48.9 bits (115), Expect = 7e-06
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 16/131 (12%)
Query: 213 PLGNFSFSSQCAFSCSEGT------NLTGIEETTC--GPFGN--WSSPEPTCQVIQCEPL 262
P G+ + + +++C NL G C P GN WSSP P C++ P
Sbjct: 1789 PFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCEL--SVPA 1846
Query: 263 SAPDLGIMNCSHPLAS----FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQK 318
+ P + H + + ++IC G L+GK C GIWS C++
Sbjct: 1847 ACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKE 1906
Query: 319 LDKSFSMIKEG 329
++ SF + G
Sbjct: 1907 VNCSFPLFMNG 1917
Score = 48.1 bits (113), Expect = 1e-05
Identities = 35/114 (30%), Positives = 48/114 (42%), Gaps = 14/114 (12%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGNWSSPEPTCQVIQCEPLSAPDLGIMNC 272
N ++ F C EG L G + C G W+S P C+ I C G +
Sbjct: 825 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG-RHT 883
Query: 273 SHPLASFSFTSACTFICS----EGT--ELIGKKKTICES----SGIWSNPSPIC 316
PL F F A + C GT +LIG+ C S +G+WS+P+P C
Sbjct: 884 GKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 937
Score = 46.6 bits (109), Expect = 4e-05
Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 14/114 (12%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGNWSSPEPTCQVIQCEPLSAPDLGIMNC 272
N ++ F C EG L G + C G W+S P C+ I C G +
Sbjct: 375 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG-RHT 433
Query: 273 SHPLASFSFTSACTFICS----EGT--ELIGKKKTICES----SGIWSNPSPIC 316
PL F F + C GT +LIG+ C S +G+WS+P+P C
Sbjct: 434 GKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487
Score = 44.3 bits (103), Expect = 2e-04
Identities = 37/144 (25%), Positives = 55/144 (38%), Gaps = 31/144 (21%)
Query: 201 EAPELGTMDCTHPLG-----------NFSFSSQCAFSCSEGTNLTGIEETTC---GPFGN 246
EAP C LG N ++ +F C EG L G + C G
Sbjct: 1249 EAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSL 1308
Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSH---PLASFSFTSACTFICSEGTE------LIG 297
W++ P C+ I C A I+N H P + ++ C + LIG
Sbjct: 1309 WNNSVPVCEHIFCPNPPA----ILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIG 1364
Query: 298 KKKTICES----SGIWSNPSPICQ 317
+ C S +G+WS+P+P C+
Sbjct: 1365 ESTIRCTSDPHGNGVWSSPAPRCE 1388
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
WSSP+ C+ C+ P G++ H + S + C+ G LIG C S
Sbjct: 542 WSSPKDVCKRKSCKTPPDPVNGMV---HVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598
Query: 307 G---IWSNPSPICQKL 319
G WS PICQ++
Sbjct: 599 GNAAHWSTKPPICQRI 614
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
WSSP+ C+ C+ P G++ H + S + C+ G LIG C S
Sbjct: 992 WSSPKDVCKRKSCKTPPDPVNGMV---HVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 307 G---IWSNPSPICQKL 319
G WS PICQ++
Sbjct: 1049 GNTAHWSTKPPICQRI 1064
Score = 42.4 bits (98), Expect = 7e-04
Identities = 37/155 (23%), Positives = 62/155 (40%), Gaps = 17/155 (10%)
Query: 189 PQCQFVIQCEPLEAPELGTMDC-THPLGNFSFSSQCAFSCSEGTN------LTGIEETTC 241
P C+ +I CEP P + D ++ +F + + C G + L G C
Sbjct: 1512 PICE-IISCEP--PPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYC 1568
Query: 242 ----GPFGNWSSPEPTCQVIQCEPLSAPDL-GIMNCSHPLASFSFTSACTFICSEGTELI 296
G WSSP P C I +AP++ + + F+ T F C G ++
Sbjct: 1569 TSKDDQVGVWSSPPPRC--ISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMV 1626
Query: 297 GKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDY 331
G C+++G W P C ++ + I G++
Sbjct: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEH 1661
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
W+ + C+ C P G++ H + F S + C++G LIG C S
Sbjct: 92 WTGAKDRCRRKSCRNPPDPVNGMV---HVIKGIQFGSQIKYSCTKGYRLIGSSSATCIIS 148
Query: 307 G---IWSNPSPICQKL 319
G IW N +PIC ++
Sbjct: 149 GDTVIWDNETPICDRI 164
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 13/129 (10%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
NF + S + C+ G+ + E P G WS P P C + +C P +
Sbjct: 1084 NFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 1143
Query: 265 PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFS 324
+ GI+ S + FS F C G + G ++ C++ W P C ++ +
Sbjct: 1144 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 1201
Query: 325 MIKEGDYNP 333
I G++ P
Sbjct: 1202 EILHGEHTP 1210
Score = 38.9 bits (89), Expect = 0.008
Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 13/115 (11%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
NF + S + C+ G+ + E P G WS P P C + +C P +
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 265 PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
+ GI+ S + FS F C G + G ++ C++ W P C ++
Sbjct: 244 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296
Score = 38.9 bits (89), Expect = 0.008
Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 13/115 (11%)
Query: 216 NFSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSA 264
NF + S + C+ G+ + E P G WS P P C + +C P +
Sbjct: 634 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 693
Query: 265 PDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
+ GI+ S + FS F C G + G ++ C++ W P C ++
Sbjct: 694 EN-GIL-VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746
Score = 36.2 bits (82), Expect = 0.049
Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 213 PLGNFSFSSQCAFSCS----EGTNLTGIEETTC----GPFGN--WSSPEPTCQVI-QCEP 261
PL F F ++C GT+ I E+T P GN WSSP P C ++ C+
Sbjct: 436 PLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ- 494
Query: 262 LSAPD---LGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTI-CESSGIWSNPSPICQ 317
APD + + F ++ + C E G+ +I C + +WS+P +C+
Sbjct: 495 --APDHFLFAKLKTQTNASDFPIGTSLKYECR--PEYYGRPFSITCLDNLVWSSPKDVCK 550
Query: 318 K 318
+
Sbjct: 551 R 551
Score = 36.2 bits (82), Expect = 0.049
Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 213 PLGNFSFSSQCAFSCS----EGTNLTGIEETTC----GPFGN--WSSPEPTCQVI-QCEP 261
PL F F ++C GT+ I E+T P GN WSSP P C ++ C+
Sbjct: 886 PLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ- 944
Query: 262 LSAPD---LGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTI-CESSGIWSNPSPICQ 317
APD + + F ++ + C E G+ +I C + +WS+P +C+
Sbjct: 945 --APDHFLFAKLKTQTNASDFPIGTSLKYECR--PEYYGRPFSITCLDNLVWSSPKDVCK 1000
Query: 318 K 318
+
Sbjct: 1001 R 1001
Score = 30.8 bits (68), Expect = 2.0
Identities = 29/142 (20%), Positives = 49/142 (34%), Gaps = 12/142 (8%)
Query: 224 AFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCE-PLSAPDLGIMNCSHPLASFSFT 282
++ C G L G C G WS + C+ + C PL GI + +
Sbjct: 1874 SYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMN--GISKELEMKKVYHYG 1931
Query: 283 SACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMV 342
T C +G L G + C++ W P C ++ FI + +
Sbjct: 1932 DYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSGTIFFILLII-- 1989
Query: 343 TAFSGLAFIIWLARRLKKGKKS 364
F+ W+ + +KG +
Sbjct: 1990 -------FLSWIILKHRKGNNA 2004
>gi|7657619 sushi-repeat-containing protein, X-linked 2 [Homo
sapiens]
Length = 465
Score = 60.8 bits (146), Expect = 2e-09
Identities = 35/118 (29%), Positives = 48/118 (40%), Gaps = 7/118 (5%)
Query: 206 GTMDCTHPLG---NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPL 262
G C P G + S ++C SC G L G C P WS C+ ++C L
Sbjct: 67 GEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHAL 125
Query: 263 SAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLD 320
G C++ + S C + CS G L G + IC G WS P+C +D
Sbjct: 126 PFITSGTYTCTNGVL---LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDID 180
Score = 42.0 bits (97), Expect = 9e-04
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 3/71 (4%)
Query: 195 IQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC 254
++C L GT CT+ + S+C +SCS G +L G C G WS EP C
Sbjct: 120 MRCHALPFITSGTYTCTNGV---LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176
Query: 255 QVIQCEPLSAP 265
I + P
Sbjct: 177 VDIDPPKIRCP 187
Score = 42.0 bits (97), Expect = 9e-04
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 255 QVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSP 314
QV +C L P G + C+ A ++ + C + C G + G +C+SS WS P
Sbjct: 260 QVRRCPTLKPPQHGYLTCTS--AGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPP 317
Query: 315 IC 316
IC
Sbjct: 318 IC 319
Score = 38.9 bits (89), Expect = 0.008
Identities = 20/77 (25%), Positives = 31/77 (40%), Gaps = 7/77 (9%)
Query: 183 DVGYYGPQCQFVIQ-----CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIE 237
D Y C+F+++ C L+ P+ G + CT N+ + C + C G + G
Sbjct: 245 DRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYG--ATCEYHCDGGYDRQGTP 302
Query: 238 ETTCGPFGNWSSPEPTC 254
C WS P C
Sbjct: 303 SRVCQSSRQWSGSPPIC 319
>gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens]
Length = 292
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 22/138 (15%)
Query: 27 CC--DFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYL-EKTLPFS 83
CC +++ H G+ W H + W A ++C+ LV I + E +++ + T PF+
Sbjct: 157 CCPVNWVEHQGSCYWFSHSGKA---WAEAEKYCQLENAHLVVINSWEEQKFIVQHTNPFN 213
Query: 84 RSYYWIGIRKIGGIWTWV-GTNKSLTEEAENWGDGEPNN-----KKNKEDCVEIYIKRNK 137
WIG+ G W WV GT+ +NW +P+N EDCVE+ +
Sbjct: 214 T---WIGLTDSDGSWKWVDGTD--YRHNYKNWAVTQPDNWHGHELGGSEDCVEV-----Q 263
Query: 138 DAGKWNDDACHKLKAALC 155
G+WNDD C ++ +C
Sbjct: 264 PDGRWNDDFCLQVYRWVC 281
>gi|18426875 asialoglycoprotein receptor 2 isoform b [Homo sapiens]
Length = 287
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 22/138 (15%)
Query: 27 CC--DFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYL-EKTLPFS 83
CC +++ H G+ W H + W A ++C+ LV I + E +++ + T PF+
Sbjct: 152 CCPVNWVEHQGSCYWFSHSGKA---WAEAEKYCQLENAHLVVINSWEEQKFIVQHTNPFN 208
Query: 84 RSYYWIGIRKIGGIWTWV-GTNKSLTEEAENWGDGEPNN-----KKNKEDCVEIYIKRNK 137
WIG+ G W WV GT+ +NW +P+N EDCVE+ +
Sbjct: 209 T---WIGLTDSDGSWKWVDGTD--YRHNYKNWAVTQPDNWHGHELGGSEDCVEV-----Q 258
Query: 138 DAGKWNDDACHKLKAALC 155
G+WNDD C ++ +C
Sbjct: 259 PDGRWNDDFCLQVYRWVC 276
>gi|18426873 asialoglycoprotein receptor 2 isoform a [Homo sapiens]
Length = 311
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 22/138 (15%)
Query: 27 CC--DFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYL-EKTLPFS 83
CC +++ H G+ W H + W A ++C+ LV I + E +++ + T PF+
Sbjct: 176 CCPVNWVEHQGSCYWFSHSGKA---WAEAEKYCQLENAHLVVINSWEEQKFIVQHTNPFN 232
Query: 84 RSYYWIGIRKIGGIWTWV-GTNKSLTEEAENWGDGEPNN-----KKNKEDCVEIYIKRNK 137
WIG+ G W WV GT+ +NW +P+N EDCVE+ +
Sbjct: 233 T---WIGLTDSDGSWKWVDGTD--YRHNYKNWAVTQPDNWHGHELGGSEDCVEV-----Q 282
Query: 138 DAGKWNDDACHKLKAALC 155
G+WNDD C ++ +C
Sbjct: 283 PDGRWNDDFCLQVYRWVC 300
>gi|4502253 asialoglycoprotein receptor 2 isoform a [Homo sapiens]
Length = 311
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 22/138 (15%)
Query: 27 CC--DFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYL-EKTLPFS 83
CC +++ H G+ W H + W A ++C+ LV I + E +++ + T PF+
Sbjct: 176 CCPVNWVEHQGSCYWFSHSGKA---WAEAEKYCQLENAHLVVINSWEEQKFIVQHTNPFN 232
Query: 84 RSYYWIGIRKIGGIWTWV-GTNKSLTEEAENWGDGEPNN-----KKNKEDCVEIYIKRNK 137
WIG+ G W WV GT+ +NW +P+N EDCVE+ +
Sbjct: 233 T---WIGLTDSDGSWKWVDGTD--YRHNYKNWAVTQPDNWHGHELGGSEDCVEV-----Q 282
Query: 138 DAGKWNDDACHKLKAALC 155
G+WNDD C ++ +C
Sbjct: 283 PDGRWNDDFCLQVYRWVC 300
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 59.7 bits (143), Expect = 4e-09
Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 26/161 (16%)
Query: 178 YTCNCDVGYYGP---QCQFVIQCEPLEAPELGTMDCTHP------------LGNFSFSSQ 222
+ C G GP +CQ + + EP E P + C P NFS +
Sbjct: 256 FRCQPGFGMKGPSHVKCQALNKWEP-ELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQE 313
Query: 223 CAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL--ASFS 280
+SC G +L G C P G+WS P C+V C+ LG + H L +
Sbjct: 314 VFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDF----LGQLPNGHVLFPLNLQ 369
Query: 281 FTSACTFICSEGTELIGKKKTICESSG---IWSNPSPICQK 318
+ F+C EG +L G + C +G +W++ P+C++
Sbjct: 370 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCER 410
Score = 52.8 bits (125), Expect = 5e-07
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 16/119 (13%)
Query: 212 HPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSPEPTCQVIQCE-PLSAPDL 267
H + + F SQ +SC +G L G TC GN W + P C I C P + +
Sbjct: 108 HVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANG 167
Query: 268 GIMNCSHPLASFSFTSACTFICSEGT------ELIGKKKTICESS----GIWSNPSPIC 316
+ S F + S T+ C+ G+ EL+G+ C S GIWS P+P C
Sbjct: 168 DFTSISREY--FHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQC 224
Score = 51.6 bits (122), Expect = 1e-06
Identities = 41/139 (29%), Positives = 57/139 (41%), Gaps = 16/139 (11%)
Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLG--NFSFSSQCAFSCSEGTNLTGIEETTC---GP 243
P+C+ V C+ LG + H L N ++ F C EG L G + C G
Sbjct: 343 PRCE-VKSCDDF----LGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGM 397
Query: 244 FGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTIC 303
W+S P C+ CE P G++ H + S + C+ G LIG C
Sbjct: 398 ESLWNSSVPVCERKSCETPPVPVNGMV---HVITDIHVGSRINYSCTTGHRLIGHSSAEC 454
Query: 304 ESSG---IWSNPSPICQKL 319
SG WS PICQ++
Sbjct: 455 ILSGNTAHWSMKPPICQQI 473
Score = 46.6 bits (109), Expect = 4e-05
Identities = 39/141 (27%), Positives = 58/141 (41%), Gaps = 22/141 (15%)
Query: 194 VIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN---WSSP 250
V + + E P + H + + S+ +SC+ G L G C GN WS
Sbjct: 407 VCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMK 466
Query: 251 EPTCQVIQCEPLSAPDLGIMNCSH---PLASFSFTSACTFICSEGTE------LIGKKKT 301
P CQ I C A I+N H PL + ++ C + LIG+ T
Sbjct: 467 PPICQQIFCPNPPA----ILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGES-T 521
Query: 302 ICESS-----GIWSNPSPICQ 317
I +S G+WS+P+P C+
Sbjct: 522 IRRTSEPHGNGVWSSPAPRCE 542
Score = 43.1 bits (100), Expect = 4e-04
Identities = 33/130 (25%), Positives = 45/130 (34%), Gaps = 6/130 (4%)
Query: 189 PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS 248
PQC +C P + L FS + F C G + G C W
Sbjct: 222 PQCIIPNKCTPPNVENGILVSDNRSL--FSLNEVVEFRCQPGFGMKGPSHVKCQALNKWE 279
Query: 249 SPEPTCQVIQCEPLSAPD-LGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSG 307
P+C + C+P PD L +FS + C G +L G C G
Sbjct: 280 PELPSCSRV-CQP--PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQG 336
Query: 308 IWSNPSPICQ 317
WS +P C+
Sbjct: 337 DWSPAAPRCE 346
Score = 42.7 bits (99), Expect = 5e-04
Identities = 34/136 (25%), Positives = 52/136 (38%), Gaps = 13/136 (9%)
Query: 187 YGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGN 246
+ QC V + P P T D P+G + + C G + C
Sbjct: 31 FSDQCN-VPEWLPFARPTNLTDDFEFPIGTY-----LNYECRPGYSGRPFS-IICLKNSV 83
Query: 247 WSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESS 306
W+S + C+ C P G+ +H + F S + C +G LIG C S
Sbjct: 84 WTSAKDKCKRKSCRNPPDPVNGM---AHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIIS 140
Query: 307 G---IWSNPSPICQKL 319
G IW N +P+C ++
Sbjct: 141 GNTVIWDNKTPVCDRI 156
Score = 33.9 bits (76), Expect = 0.24
Identities = 27/114 (23%), Positives = 43/114 (37%), Gaps = 13/114 (11%)
Query: 217 FSFSSQCAFSCSEGTNLTGIEETTCGP----------FGNWSSPEPTCQVI-QCEPLSAP 265
F + S + C+ G+ + E P G WS P P C + +C P +
Sbjct: 177 FHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVE 236
Query: 266 DLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKL 319
+ GI+ S + FS F C G + G C++ W P C ++
Sbjct: 237 N-GIL-VSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRV 288
Score = 30.0 bits (66), Expect = 3.5
Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 20/103 (19%)
Query: 167 GHGECVEIINNYTCNCDVGYYGPQCQFVIQCEP---LEAPELGTMDCTHPLGNFSFSSQC 223
GH I++ T + + P CQ + P L GT PLG+ + +
Sbjct: 448 GHSSAECILSGNTAHWSMK--PPICQQIFCPNPPAILNGRHTGT-----PLGDIPYGKEV 500
Query: 224 AFSCS----EGTNLTGIEETTCG----PFGN--WSSPEPTCQV 256
+++C G I E+T P GN WSSP P C++
Sbjct: 501 SYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCEL 543
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.469
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,802,333
Number of Sequences: 37866
Number of extensions: 839246
Number of successful extensions: 3927
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 186
Number of HSP's successfully gapped in prelim test: 164
Number of HSP's that attempted gapping in prelim test: 2044
Number of HSP's gapped (non-prelim): 1431
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.