Guide to the Human Genome
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Search of human proteins with 4506585

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506585 replication protein A2, 32kDa [Homo sapiens]
         (270 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506585 replication protein A2, 32kDa [Homo sapiens]               542   e-154
gi|9558731 replication protein A4, 34kDa [Homo sapiens]               209   2e-54
gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a ...    31   1.00 
gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b ...    31   1.00 
gi|4505723 peroxisomal biogenesis factor 13 [Homo sapiens]             31   1.3  
gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform ...    30   2.9  
gi|16933525 unc5C [Homo sapiens]                                       29   3.8  
gi|4502111 annexin VII isoform 1 [Homo sapiens]                        29   3.8  
gi|66932918 MER receptor tyrosine kinase precursor [Homo sapiens]      29   4.9  
gi|91982772 mucin 17 [Homo sapiens]                                    29   4.9  
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]              28   6.5  
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]             28   6.5  
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor...    28   6.5  
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform...    28   6.5  
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi...    28   6.5  
gi|4809279 annexin VII isoform 2 [Homo sapiens]                        28   8.4  

>gi|4506585 replication protein A2, 32kDa [Homo sapiens]
          Length = 270

 Score =  542 bits (1396), Expect = e-154
 Identities = 270/270 (100%), Positives = 270/270 (100%)

Query: 1   MWNSGFESYGSSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSATLV 60
           MWNSGFESYGSSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSATLV
Sbjct: 1   MWNSGFESYGSSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSATLV 60

Query: 61  DEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENTVV 120
           DEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENTVV
Sbjct: 61  DEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENTVV 120

Query: 121 PPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGR 180
           PPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGR
Sbjct: 121 PPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGR 180

Query: 181 APISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVS 240
           APISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVS
Sbjct: 181 APISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVS 240

Query: 241 SIKQAVDFLSNEGHIYSTVDDDHFKSTDAE 270
           SIKQAVDFLSNEGHIYSTVDDDHFKSTDAE
Sbjct: 241 SIKQAVDFLSNEGHIYSTVDDDHFKSTDAE 270


>gi|9558731 replication protein A4, 34kDa [Homo sapiens]
          Length = 261

 Score =  209 bits (533), Expect = 2e-54
 Identities = 123/270 (45%), Positives = 164/270 (60%), Gaps = 11/270 (4%)

Query: 1   MWNSGFESYGSSSY--GGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSAT 58
           M  SGF SYGS S   G +GG  Q      +PA     ++ + R Q +VPC ++QLLS+T
Sbjct: 1   MSKSGFGSYGSISAADGASGGSDQLCERDATPAIKT--QRPKVRIQDVVPCNVNQLLSST 58

Query: 59  LVDEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENT 118
           + D VF++  + +SQV+IVG+IR AEKA  +I YKIDDMTA P++ RQW   +    + T
Sbjct: 59  VFDPVFKVRGIIVSQVSIVGVIRGAEKASNHICYKIDDMTAKPIEARQWFGREKV-KQVT 117

Query: 119 VVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSA 178
            +    YVKV G L+     KSL   KI  LEDMNEFT HILE +NAHM+L KA    + 
Sbjct: 118 PLSVGVYVKVFGILKCPTGTKSLEVLKIHVLEDMNEFTVHILETVNAHMMLDKARRDTTV 177

Query: 179 GRAPISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMS 238
              P+S    SE  + G N     N +   Q++VL LI  CP  EG +  +L+ QL  +S
Sbjct: 178 ESVPVS---PSEVNDAGDNDESHRNFI---QDEVLRLIHECPHQEGKSIHELRAQLCDLS 231

Query: 239 VSSIKQAVDFLSNEGHIYSTVDDDHFKSTD 268
           V +IK+A+D+L+ EGHIY TVD +HFKS D
Sbjct: 232 VKAIKEAIDYLTVEGHIYPTVDREHFKSAD 261


>gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a
           [Homo sapiens]
          Length = 355

 Score = 31.2 bits (69), Expect = 1.00
 Identities = 11/27 (40%), Positives = 16/27 (59%)

Query: 2   WNSGFESYGSSSYGGAGGYTQSPGGFG 28
           WN G+ +Y +  YG  G  +Q  GG+G
Sbjct: 290 WNQGYSNYWNQGYGNYGYNSQGYGGYG 316



 Score = 29.6 bits (65), Expect = 2.9
 Identities = 12/21 (57%), Positives = 14/21 (66%), Gaps = 2/21 (9%)

Query: 2   WNSGFESYG--SSSYGGAGGY 20
           WN G+ +YG  S  YGG GGY
Sbjct: 298 WNQGYGNYGYNSQGYGGYGGY 318


>gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b
           [Homo sapiens]
          Length = 336

 Score = 31.2 bits (69), Expect = 1.00
 Identities = 11/27 (40%), Positives = 16/27 (59%)

Query: 2   WNSGFESYGSSSYGGAGGYTQSPGGFG 28
           WN G+ +Y +  YG  G  +Q  GG+G
Sbjct: 271 WNQGYSNYWNQGYGNYGYNSQGYGGYG 297



 Score = 29.6 bits (65), Expect = 2.9
 Identities = 12/21 (57%), Positives = 14/21 (66%), Gaps = 2/21 (9%)

Query: 2   WNSGFESYG--SSSYGGAGGY 20
           WN G+ +YG  S  YGG GGY
Sbjct: 279 WNQGYGNYGYNSQGYGGYGGY 299


>gi|4505723 peroxisomal biogenesis factor 13 [Homo sapiens]
          Length = 403

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 16/73 (21%)

Query: 2   WNSGFESYGSSSYGGAGGYTQSPGGFG-----------SPAPSQAEKKSRARAQHIVP-- 48
           ++SG+ +YG+S YGG   Y+    G G           S    QAE+ SR   Q I    
Sbjct: 78  FSSGYGAYGNSFYGGYSPYSYGYNGLGYNRLRVDDLPPSRFVQQAEESSRGAFQSIESIV 137

Query: 49  ---CTISQLLSAT 58
               ++S ++ AT
Sbjct: 138 HAFASVSMMMDAT 150


>gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform a
           [Homo sapiens]
          Length = 332

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 7/38 (18%)

Query: 2   WNSGFESYGSSSYG-------GAGGYTQSPGGFGSPAP 32
           WN G+ +Y +  YG       G GGY  SP G+    P
Sbjct: 268 WNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGP 305


>gi|16933525 unc5C [Homo sapiens]
          Length = 931

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 20/82 (24%), Positives = 43/82 (52%), Gaps = 10/82 (12%)

Query: 146 IMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGRAPISNPGMSEAGNF---GGNSFMPA 202
           + P +D++EFT+ +   +   ++ ++A S  +   A  ++P  +  G+F   GG+  +P 
Sbjct: 488 VTPQDDLSEFTSKLSPQMTQSLLENEALSLKNQSLARQTDPSCTAFGSFNSLGGHLIVPN 547

Query: 203 NGLTVAQNQVLNLIKACPRPEG 224
           +G+++       LI A   P+G
Sbjct: 548 SGVSL-------LIPAGAIPQG 562


>gi|4502111 annexin VII isoform 1 [Homo sapiens]
          Length = 466

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 3/57 (5%)

Query: 4   SGFESYGSSSYGGAGGYTQSPGGF-GSPAPSQAEKKSRARAQHIVPCTISQLLSATL 59
           SG+    S SYGG       PGGF G   PSQ             P T++Q+   T+
Sbjct: 103 SGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQPTYPSQ--PATVTQVTQGTI 157


>gi|66932918 MER receptor tyrosine kinase precursor [Homo sapiens]
          Length = 999

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 170 SKANSQPSAGRAPISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRP 222
           S+ N QP    + ++ PG++E   F   +     GLTV++   +N IKA P P
Sbjct: 236 SRVNEQPEKSPSVLTVPGLTEMAVFSCEAHND-KGLTVSKGVQIN-IKAIPSP 286


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 29/128 (22%), Positives = 53/128 (41%), Gaps = 12/128 (9%)

Query: 67   GNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENTVVPPETYV 126
            G+  ++ + +   +  + +A T +   +D  T  P+     V +  T +E T +P  TY 
Sbjct: 1276 GSTLLTSIPVSTTLVTSPEASTLLTTPVD--TKGPVVTSNEVSSSPTPAEGTSMPTSTYS 1333

Query: 127  KVAGHLRSFQNKKSLVA------FKIMPLEDMNEFTTHILEVINAHMV---LSKANSQPS 177
            +    L S     +LVA          P+++    TT   E  ++       S  NS PS
Sbjct: 1334 EGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTS-TEACSSPTTSEGTSMPNSNPS 1392

Query: 178  AGRAPISN 185
             G  P+++
Sbjct: 1393 EGTTPLTS 1400


>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
          Length = 849

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 33/139 (23%), Positives = 57/139 (41%), Gaps = 11/139 (7%)

Query: 38  KSRARAQHIVPCTISQLLSATLVDEVFRIGNVEISQVTI-VGIIRHAEKAPTNIVYKIDD 96
           K + +    +   I+Q LS  L    FR+   EI  + + V   R AE    N++  + D
Sbjct: 443 KKKIKELKFLDSKIAQNLSIFLSS--FRVPYEEIRMMILEVDETRLAESMIQNLIKHLPD 500

Query: 97  MTAAPMDVRQWVDTDDTSSE-NTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEF 155
                    Q        SE + +  PE +V V  +++  + + S + FK+   E +N  
Sbjct: 501 Q-------EQLNSLSQFKSEYSNLCEPEQFVVVMSNVKRLRPRLSAILFKLQFEEQVNNI 553

Query: 156 TTHILEVINAHMVLSKANS 174
              I+ V  A   + K+ S
Sbjct: 554 KPDIMAVSTACEEIKKSKS 572


>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
          Length = 1193

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 33/139 (23%), Positives = 57/139 (41%), Gaps = 11/139 (7%)

Query: 38  KSRARAQHIVPCTISQLLSATLVDEVFRIGNVEISQVTI-VGIIRHAEKAPTNIVYKIDD 96
           K + +    +   I+Q LS  L    FR+   EI  + + V   R AE    N++  + D
Sbjct: 706 KKKIKELKFLDSKIAQNLSIFLSS--FRVPYEEIRMMILEVDETRLAESMIQNLIKHLPD 763

Query: 97  MTAAPMDVRQWVDTDDTSSE-NTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEF 155
                    Q        SE + +  PE +V V  +++  + + S + FK+   E +N  
Sbjct: 764 Q-------EQLNSLSQFKSEYSNLCEPEQFVVVMSNVKRLRPRLSAILFKLQFEEQVNNI 816

Query: 156 TTHILEVINAHMVLSKANS 174
              I+ V  A   + K+ S
Sbjct: 817 KPDIMAVSTACEEIKKSKS 835


>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
           B1 [Homo sapiens]
          Length = 353

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 11/26 (42%), Positives = 14/26 (53%)

Query: 3   NSGFESYGSSSYGGAGGYTQSPGGFG 28
           N G  +YGS +Y   G Y Q P  +G
Sbjct: 289 NYGGGNYGSGNYNDFGNYNQQPSNYG 314


>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
           [Homo sapiens]
          Length = 341

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 11/26 (42%), Positives = 14/26 (53%)

Query: 3   NSGFESYGSSSYGGAGGYTQSPGGFG 28
           N G  +YGS +Y   G Y Q P  +G
Sbjct: 277 NYGGGNYGSGNYNDFGNYNQQPSNYG 302


>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
           sapiens]
          Length = 305

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 12/24 (50%), Positives = 13/24 (54%)

Query: 5   GFESYGSSSYGGAGGYTQSPGGFG 28
           G+ SYG    GG GGY    GG G
Sbjct: 216 GYNSYGGYGGGGGGGYNAYGGGGG 239


>gi|4809279 annexin VII isoform 2 [Homo sapiens]
          Length = 488

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 15/32 (46%), Positives = 16/32 (50%), Gaps = 1/32 (3%)

Query: 4   SGFESYGSSSYGGAGGYTQSPGGF-GSPAPSQ 34
           SG+    S SYGG       PGGF G   PSQ
Sbjct: 103 SGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQ 134


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,427,011
Number of Sequences: 37866
Number of extensions: 462033
Number of successful extensions: 1639
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1607
Number of HSP's gapped (non-prelim): 36
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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