Guide to the Human Genome
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Search of human proteins with 4506491

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506491 replication factor C 4 [Homo sapiens]
         (363 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31881687 replication factor C 4 [Homo sapiens]                     706   0.0  
gi|4506491 replication factor C 4 [Homo sapiens]                      706   0.0  
gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]            219   3e-57
gi|194306571 replication factor C 5 isoform 2 [Homo sapiens]          210   1e-54
gi|194306567 replication factor C 5 isoform 2 [Homo sapiens]          210   1e-54
gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]           199   4e-51
gi|194306569 replication factor C 5 isoform 3 [Homo sapiens]          152   6e-37
gi|28882049 replication factor C 2 isoform 2 [Homo sapiens]           151   1e-36
gi|108773789 replication factor C 3 isoform 2 [Homo sapiens]          113   3e-25
gi|4506489 replication factor C 3 isoform 1 [Homo sapiens]            113   3e-25
gi|32528306 replication factor C large subunit [Homo sapiens]          52   1e-06
gi|27501458 CTF18, chromosome transmission fidelity factor 18 ho...    45   8e-05
gi|31377667 peroxisomal LON protease-like [Homo sapiens]               43   4e-04
gi|19718796 RAD17 homolog isoform 1 [Homo sapiens]                     40   0.002
gi|19718794 RAD17 homolog isoform 1 [Homo sapiens]                     40   0.002
gi|19718792 RAD17 homolog isoform 1 [Homo sapiens]                     40   0.002
gi|19718784 RAD17 homolog isoform 1 [Homo sapiens]                     40   0.002
gi|4506383 RAD17 homolog isoform 1 [Homo sapiens]                      40   0.002
gi|19718786 RAD17 homolog isoform 2 [Homo sapiens]                     40   0.002
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]            39   0.007
gi|219282747 KIAA1772 [Homo sapiens]                                   37   0.021
gi|18426904 Werner helicase interacting protein isoform 2 [Homo ...    37   0.028
gi|18426902 Werner helicase interacting protein isoform 1 [Homo ...    37   0.028
gi|6005942 valosin-containing protein [Homo sapiens]                   35   0.080
gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]      35   0.14 
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]            35   0.14 
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                  34   0.18 
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                  34   0.18 
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]                       34   0.23 
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]                        34   0.23 

>gi|31881687 replication factor C 4 [Homo sapiens]
          Length = 363

 Score =  706 bits (1822), Expect = 0.0
 Identities = 363/363 (100%), Positives = 363/363 (100%)

Query: 1   MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVA 60
           MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVA
Sbjct: 1   MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVA 60

Query: 61  VLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVR 120
           VLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVR
Sbjct: 61  VLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVR 120

Query: 121 EKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC 180
           EKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC
Sbjct: 121 EKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC 180

Query: 181 NYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRK 240
           NYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRK
Sbjct: 181 NYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRK 240

Query: 241 AITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEG 300
           AITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEG
Sbjct: 241 AITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEG 300

Query: 301 HAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLS 360
           HAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLS
Sbjct: 301 HAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLS 360

Query: 361 QNC 363
           QNC
Sbjct: 361 QNC 363


>gi|4506491 replication factor C 4 [Homo sapiens]
          Length = 363

 Score =  706 bits (1822), Expect = 0.0
 Identities = 363/363 (100%), Positives = 363/363 (100%)

Query: 1   MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVA 60
           MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVA
Sbjct: 1   MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVA 60

Query: 61  VLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVR 120
           VLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVR
Sbjct: 61  VLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVR 120

Query: 121 EKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC 180
           EKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC
Sbjct: 121 EKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC 180

Query: 181 NYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRK 240
           NYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRK
Sbjct: 181 NYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRK 240

Query: 241 AITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEG 300
           AITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEG
Sbjct: 241 AITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEG 300

Query: 301 HAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLS 360
           HAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLS
Sbjct: 301 HAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLS 360

Query: 361 QNC 363
           QNC
Sbjct: 361 QNC 363


>gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]
          Length = 340

 Score =  219 bits (558), Expect = 3e-57
 Identities = 125/321 (38%), Positives = 196/321 (61%), Gaps = 10/321 (3%)

Query: 34  KAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAAR 93
           K + +PWVEKYRP+ ++++   +++++ ++K +    LP+LL YGPPGTGKTSTILA A+
Sbjct: 16  KIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAK 75

Query: 94  ELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEAD 153
           +L+  + F   VLELNASD+RGI ++R  + +FA       +        FK+VILDEAD
Sbjct: 76  QLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-------FKLVILDEAD 128

Query: 154 SMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLD 213
           +MT  AQ ALRR +EK ++ TRFCLICNY+S+II  L SRC++FRF PL+ ++   RL  
Sbjct: 129 AMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEH 188

Query: 214 IAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEK 273
           + ++E V IS++G+  LV +S GD+R+A+  LQS T +  GK +TE+ +    G      
Sbjct: 189 VVEEEKVDISEDGMKALVTLSSGDMRRALNILQS-TNMAFGK-VTEETVYTCTGHPLKSD 246

Query: 274 IDGVFAACQSGSFDKLEAVVKDLID-EGHAATQLVNQLHDVVVENNLSDKQKSIITEKLA 332
           I  +     +  F      + +L   +G A   ++ ++H  V   +     +  +  K+A
Sbjct: 247 IANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMA 306

Query: 333 EVDKCLADGADEHLQLISLCA 353
           +++  L+ G +E +QL SL A
Sbjct: 307 DIEYRLSVGTNEKIQLSSLIA 327


>gi|194306571 replication factor C 5 isoform 2 [Homo sapiens]
          Length = 319

 Score =  210 bits (535), Expect = 1e-54
 Identities = 122/314 (38%), Positives = 191/314 (60%), Gaps = 10/314 (3%)

Query: 41  VEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPEL 100
           VEKYRP+ ++++   +++++ ++K +    LP+LL YGPPGTGKTSTILA A++L+  + 
Sbjct: 2   VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61

Query: 101 FRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQ 160
           F   VLELNASD+RGI ++R  + +FA       +        FK+VILDEAD+MT  AQ
Sbjct: 62  FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-------FKLVILDEADAMTQDAQ 114

Query: 161 AALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENV 220
            ALRR +EK ++ TRFCLICNY+S+II  L SRC++FRF PL+ ++   RL  + ++E V
Sbjct: 115 NALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKV 174

Query: 221 KISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAA 280
            IS++G+  LV +S GD+R+A+  LQS T +  GK +TE+ +    G      I  +   
Sbjct: 175 DISEDGMKALVTLSSGDMRRALNILQS-TNMAFGK-VTEETVYTCTGHPLKSDIANILDW 232

Query: 281 CQSGSFDKLEAVVKDLID-EGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLA 339
             +  F      + +L   +G A   ++ ++H  V   +     +  +  K+A+++  L+
Sbjct: 233 MLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLS 292

Query: 340 DGADEHLQLISLCA 353
            G +E +QL SL A
Sbjct: 293 VGTNEKIQLSSLIA 306


>gi|194306567 replication factor C 5 isoform 2 [Homo sapiens]
          Length = 319

 Score =  210 bits (535), Expect = 1e-54
 Identities = 122/314 (38%), Positives = 191/314 (60%), Gaps = 10/314 (3%)

Query: 41  VEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPEL 100
           VEKYRP+ ++++   +++++ ++K +    LP+LL YGPPGTGKTSTILA A++L+  + 
Sbjct: 2   VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61

Query: 101 FRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQ 160
           F   VLELNASD+RGI ++R  + +FA       +        FK+VILDEAD+MT  AQ
Sbjct: 62  FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-------FKLVILDEADAMTQDAQ 114

Query: 161 AALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENV 220
            ALRR +EK ++ TRFCLICNY+S+II  L SRC++FRF PL+ ++   RL  + ++E V
Sbjct: 115 NALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKV 174

Query: 221 KISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAA 280
            IS++G+  LV +S GD+R+A+  LQS T +  GK +TE+ +    G      I  +   
Sbjct: 175 DISEDGMKALVTLSSGDMRRALNILQS-TNMAFGK-VTEETVYTCTGHPLKSDIANILDW 232

Query: 281 CQSGSFDKLEAVVKDLID-EGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLA 339
             +  F      + +L   +G A   ++ ++H  V   +     +  +  K+A+++  L+
Sbjct: 233 MLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLS 292

Query: 340 DGADEHLQLISLCA 353
            G +E +QL SL A
Sbjct: 293 VGTNEKIQLSSLIA 306


>gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]
          Length = 354

 Score =  199 bits (505), Expect = 4e-51
 Identities = 124/334 (37%), Positives = 190/334 (56%), Gaps = 17/334 (5%)

Query: 27  GSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTS 86
           GS+G  +    +PWVEKYRP  ++E+   E+ V+ L+      ++PN++  GPPGTGKT+
Sbjct: 29  GSAGHYE----LPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTT 84

Query: 87  TILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKI 146
           +IL  AR L GP L +  +LELNAS++RGI VVR K+K FAQ  V+       P    KI
Sbjct: 85  SILCLARALLGPAL-KDAMLELNASNDRGIDVVRNKIKMFAQQKVT------LPKGRHKI 137

Query: 147 VILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKI 206
           +ILDEADSMT  AQ ALRRTME  SKTTRF L CN   +IIEP+ SRC+  R+  L+D  
Sbjct: 138 IILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQ 197

Query: 207 QQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTG--GKEITEKVITD 264
              RL+++ +KE V  +D+G+  ++  ++GD+R+A+  LQS     G    E   KV  +
Sbjct: 198 ILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDE 257

Query: 265 IAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQK 324
              ++  E I      C + + D+   ++  L   G++   ++  +  V     +++  K
Sbjct: 258 PHPLLVKEMIQ----HCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLK 313

Query: 325 SIITEKLAEVDKCLADGADEHLQLISLCATVMQQ 358
               +++      +A+G +  LQ+  L A + Q+
Sbjct: 314 LEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQK 347


>gi|194306569 replication factor C 5 isoform 3 [Homo sapiens]
          Length = 255

 Score =  152 bits (383), Expect = 6e-37
 Identities = 94/250 (37%), Positives = 145/250 (58%), Gaps = 10/250 (4%)

Query: 105 VLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALR 164
           VLELNASD+RGI ++R  + +FA       +        FK+VILDEAD+MT  AQ ALR
Sbjct: 2   VLELNASDDRGIDIIRGPILSFASTRTIFKKG-------FKLVILDEADAMTQDAQNALR 54

Query: 165 RTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISD 224
           R +EK ++ TRFCLICNY+S+II  L SRC++FRF PL+ ++   RL  + ++E V IS+
Sbjct: 55  RVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISE 114

Query: 225 EGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSG 284
           +G+  LV +S GD+R+A+  LQS T +  GK +TE+ +    G      I  +     + 
Sbjct: 115 DGMKALVTLSSGDMRRALNILQS-TNMAFGK-VTEETVYTCTGHPLKSDIANILDWMLNQ 172

Query: 285 SFDKLEAVVKDLID-EGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGAD 343
            F      + +L   +G A   ++ ++H  V   +     +  +  K+A+++  L+ G +
Sbjct: 173 DFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTN 232

Query: 344 EHLQLISLCA 353
           E +QL SL A
Sbjct: 233 EKIQLSSLIA 242


>gi|28882049 replication factor C 2 isoform 2 [Homo sapiens]
          Length = 320

 Score =  151 bits (381), Expect = 1e-36
 Identities = 104/334 (31%), Positives = 166/334 (49%), Gaps = 51/334 (15%)

Query: 27  GSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTS 86
           GS+G  +    +PWVEKYRP  ++E+   E+ V+ L+      ++PN++  GPPGTGKT+
Sbjct: 29  GSAGHYE----LPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTT 84

Query: 87  TILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKI 146
           +IL  AR L GP L +  +LELNAS+                                  
Sbjct: 85  SILCLARALLGPAL-KDAMLELNASN---------------------------------- 109

Query: 147 VILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKI 206
                 DSMT  AQ ALRRTME  SKTTRF L CN   +IIEP+ SRC+  R+  L+D  
Sbjct: 110 ------DSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQ 163

Query: 207 QQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTG--GKEITEKVITD 264
              RL+++ +KE V  +D+G+  ++  ++GD+R+A+  LQS     G    E   KV  +
Sbjct: 164 ILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDE 223

Query: 265 IAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQK 324
              ++  E I      C + + D+   ++  L   G++   ++  +  V     +++  K
Sbjct: 224 PHPLLVKEMIQ----HCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLK 279

Query: 325 SIITEKLAEVDKCLADGADEHLQLISLCATVMQQ 358
               +++      +A+G +  LQ+  L A + Q+
Sbjct: 280 LEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQK 313


>gi|108773789 replication factor C 3 isoform 2 [Homo sapiens]
          Length = 305

 Score =  113 bits (282), Expect = 3e-25
 Identities = 77/233 (33%), Positives = 113/233 (48%), Gaps = 29/233 (12%)

Query: 40  WVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPE 99
           WV+KYRP  +  + + +E  A L+  ++  D P+LL YGP G GK + I+   REL+G  
Sbjct: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63

Query: 100 LFRLRV-----------------------LELNASDERGIQ--VVREKVKNFAQLTVSGS 134
           + +LR+                       LE+N SD       V++E +K  AQ     +
Sbjct: 64  VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123

Query: 135 RSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRC 194
            S       FK+V+L E D +T  AQ ALRRTMEK   T R  L CN  S++I P+ SRC
Sbjct: 124 NSQRD----FKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRC 179

Query: 195 SKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQS 247
              R    S +     L  + KKE + +  +    L + S  +LRKA+   ++
Sbjct: 180 LAVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEA 232


>gi|4506489 replication factor C 3 isoform 1 [Homo sapiens]
          Length = 356

 Score =  113 bits (282), Expect = 3e-25
 Identities = 77/233 (33%), Positives = 113/233 (48%), Gaps = 29/233 (12%)

Query: 40  WVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPE 99
           WV+KYRP  +  + + +E  A L+  ++  D P+LL YGP G GK + I+   REL+G  
Sbjct: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63

Query: 100 LFRLRV-----------------------LELNASDERGIQ--VVREKVKNFAQLTVSGS 134
           + +LR+                       LE+N SD       V++E +K  AQ     +
Sbjct: 64  VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123

Query: 135 RSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRC 194
            S       FK+V+L E D +T  AQ ALRRTMEK   T R  L CN  S++I P+ SRC
Sbjct: 124 NSQRD----FKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRC 179

Query: 195 SKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQS 247
              R    S +     L  + KKE + +  +    L + S  +LRKA+   ++
Sbjct: 180 LAVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEA 232


>gi|32528306 replication factor C large subunit [Homo sapiens]
          Length = 1147

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 61/250 (24%), Positives = 101/250 (40%), Gaps = 41/250 (16%)

Query: 26  AGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSL------------------- 66
           A  S ENK  + + WV+KY+P  +  +  Q+   +   K L                   
Sbjct: 573 ADDSSENK-VENLLWVDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSEDKKHAKF 631

Query: 67  -------EGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVV 119
                  +G+     L  GPPG GKT+T     +EL          +ELNASD R    +
Sbjct: 632 GKFSGKDDGSSFKAALLSGPPGVGKTTTASLVCQEL------GYSYVELNASDTRSKSSL 685

Query: 120 REKV-KNFAQLTVSGSRSDG--KPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRF 176
           +  V ++    ++ G  S+G          +I+DE D M         + +    K T+ 
Sbjct: 686 KAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDEVDGMAGNEDRGGIQELIGLIKHTKI 745

Query: 177 CLICNYVSR---IIEPLTSRCSKFRF-KPLSDKIQQQRLLDIAKKENVKISDEGIAYLVK 232
            +IC    R    I  L   C   RF +P  ++I +  ++ IA KE +KI    +  ++ 
Sbjct: 746 PIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQI-KGAMMSIAFKEGLKIPPPAMNEIIL 804

Query: 233 VSEGDLRKAI 242
            +  D+R+ +
Sbjct: 805 GANQDIRQVL 814


>gi|27501458 CTF18, chromosome transmission fidelity factor 18
           homolog [Homo sapiens]
          Length = 975

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 59/250 (23%), Positives = 95/250 (38%), Gaps = 45/250 (18%)

Query: 31  ENKKAKPVPWVEKYRPKCVDEV-----AFQEEVVAVLKKSLEGADLPN---LLFYGPPGT 82
           E    KP P VE  R            + ++ +  +L+  L+ +  P     L  GPPG 
Sbjct: 319 ERPSRKPRPSVEPARVSKEATAPGKWKSHEQVLEEMLEAGLDPSQRPKQKVALLCGPPGL 378

Query: 83  GKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCP 142
           GKT+     AR           V+E+NASD+R  +V R +++   Q+  S   + GKP  
Sbjct: 379 GKTTLAHVIARHA------GYSVVEMNASDDRSPEVFRTRIEAATQME-SVLGAGGKP-- 429

Query: 143 PFKIVILDEADSMTSAAQAAL-------------------------RRTMEKESKTTRFC 177
               +++DE D    AA   L                         RR  E         
Sbjct: 430 --NCLVIDEIDGAPVAAINVLLSILNRKGPQEVGPQGPAVPSGGGRRRRAEGGLLMRPII 487

Query: 178 LICN-YVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEG 236
            ICN   +  +  L  +     F P       QRL +++ ++ ++     +A L + ++ 
Sbjct: 488 CICNDQFAPSLRQLKQQAFLLHFPPTLPSRLVQRLQEVSLRQGMRADPGVLAALCEKTDN 547

Query: 237 DLRKAITFLQ 246
           D+R  I  LQ
Sbjct: 548 DIRACINTLQ 557


>gi|31377667 peroxisomal LON protease-like [Homo sapiens]
          Length = 852

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 49/191 (25%), Positives = 94/191 (49%), Gaps = 22/191 (11%)

Query: 41  VEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPEL 100
           +EK + + ++ +A ++     LK +L+G   P L F GPPG GKTS   + A+ L G E 
Sbjct: 346 MEKLKKRVLEYLAVRQ-----LKNNLKG---PILCFVGPPGVGKTSVGRSVAKTL-GREF 396

Query: 101 FRLRVLEL-NASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAA 159
            R+ +  + + SD RG +  R  V +     ++G ++ G   P F   +LDE D +  + 
Sbjct: 397 HRIALGGVCDQSDIRGHR--RTYVGSMPGRIINGLKTVGVNNPVF---LLDEVDKLGKSL 451

Query: 160 Q----AALRRTMEKESK---TTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLL 212
           Q    AAL   ++ E     T  +  +   +S+++   T+  +      L D+++  ++ 
Sbjct: 452 QGDPAAALLEVLDPEQNHNFTDHYLNVAFDLSQVLFIATANTTATIPAALLDRMEIIQVP 511

Query: 213 DIAKKENVKIS 223
              ++E ++I+
Sbjct: 512 GYTQEEKIEIA 522


>gi|19718796 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 8/64 (12%)

Query: 39  PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN--------LLFYGPPGTGKTSTILA 90
           PWV+KY+P+   E+A  ++ +  ++  L+   L          LL  GPPG GKT+T+  
Sbjct: 79  PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138

Query: 91  AARE 94
            ++E
Sbjct: 139 LSKE 142


>gi|19718794 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 8/64 (12%)

Query: 39  PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN--------LLFYGPPGTGKTSTILA 90
           PWV+KY+P+   E+A  ++ +  ++  L+   L          LL  GPPG GKT+T+  
Sbjct: 79  PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138

Query: 91  AARE 94
            ++E
Sbjct: 139 LSKE 142


>gi|19718792 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 8/64 (12%)

Query: 39  PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN--------LLFYGPPGTGKTSTILA 90
           PWV+KY+P+   E+A  ++ +  ++  L+   L          LL  GPPG GKT+T+  
Sbjct: 79  PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138

Query: 91  AARE 94
            ++E
Sbjct: 139 LSKE 142


>gi|19718784 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 8/64 (12%)

Query: 39  PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN--------LLFYGPPGTGKTSTILA 90
           PWV+KY+P+   E+A  ++ +  ++  L+   L          LL  GPPG GKT+T+  
Sbjct: 79  PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138

Query: 91  AARE 94
            ++E
Sbjct: 139 LSKE 142


>gi|4506383 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 8/64 (12%)

Query: 39  PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN--------LLFYGPPGTGKTSTILA 90
           PWV+KY+P+   E+A  ++ +  ++  L+   L          LL  GPPG GKT+T+  
Sbjct: 79  PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138

Query: 91  AARE 94
            ++E
Sbjct: 139 LSKE 142


>gi|19718786 RAD17 homolog isoform 2 [Homo sapiens]
          Length = 681

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 8/64 (12%)

Query: 39  PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN--------LLFYGPPGTGKTSTILA 90
           PWV+KY+P+   E+A  ++ +  ++  L+   L          LL  GPPG GKT+T+  
Sbjct: 90  PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 149

Query: 91  AARE 94
            ++E
Sbjct: 150 LSKE 153


>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
          Length = 403

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 55/194 (28%), Positives = 85/194 (43%), Gaps = 41/194 (21%)

Query: 75  LFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDE---RGIQVVREKVKNFAQLTV 131
           L YGPPGTGKT    A A +L   +   L+V+  +  D+      +++RE + N+A+   
Sbjct: 185 LLYGPPGTGKTLLARAVASQL---DCNFLKVVSSSIVDKYIGESARLIRE-MFNYAR--- 237

Query: 132 SGSRSDGKPCPPFKIVILDEADSM--------TSAAQAALRRTMEKESKTTRF------- 176
                D +PC    I+ +DE D++        TSA +   R  ME  ++   F       
Sbjct: 238 -----DHQPC----IIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVK 288

Query: 177 CLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEG-IAY--LVKV 233
            ++       ++P   R  +   K   D   +Q  LDI K     I+  G I Y  +VK+
Sbjct: 289 MIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKL 348

Query: 234 SEG----DLRKAIT 243
           S+G    DLR   T
Sbjct: 349 SDGFNGADLRNVCT 362


>gi|219282747 KIAA1772 [Homo sapiens]
          Length = 1923

 Score = 37.4 bits (85), Expect = 0.021
 Identities = 43/165 (26%), Positives = 67/165 (40%), Gaps = 40/165 (24%)

Query: 38   VPWVEKYRPKCVDEVAFQEEVVAVLKKSL---EGADLPN---------------LLFYGP 79
            V WV   RP    +++ +E+ +   + +L     AD  N               LL  GP
Sbjct: 1262 VAWVSSLRPLLNKDMSSEEQSLYYRQWTLARQHHADYSNQLDPASGTRNFHPRRLLLTGP 1321

Query: 80   PGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGK 139
            P  GKT + L   R LF      +R+LE++  DE  I     +    +Q       S+G+
Sbjct: 1322 PQVGKTGSYLQFLRILF---RMLIRLLEVDVYDEEEINTDHNESSEVSQ-------SEGE 1371

Query: 140  PCP--------PFKIVILDEADSMTSAAQ----AALRRTMEKESK 172
            P P        PF + + D   S+ S       A +++ + KESK
Sbjct: 1372 PWPDIESFSKMPFDVSVHDPKYSLMSLVYTEKLAGVKQEVIKESK 1416


>gi|18426904 Werner helicase interacting protein isoform 2 [Homo
           sapiens]
          Length = 640

 Score = 37.0 bits (84), Expect = 0.028
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 5/93 (5%)

Query: 39  PWVEKYRPKCVDEVAFQEEVVA---VLKKSLEGADLPNLLFYGPPGTGKTST--ILAAAR 93
           P  +  RP  + +   Q + V    +L+  LE  ++P+L+ +GPPG GKT+   I+A+  
Sbjct: 226 PLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIASNS 285

Query: 94  ELFGPELFRLRVLELNASDERGIQVVREKVKNF 126
           +        L       +D R +    +  K+F
Sbjct: 286 KKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSF 318


>gi|18426902 Werner helicase interacting protein isoform 1 [Homo
           sapiens]
          Length = 665

 Score = 37.0 bits (84), Expect = 0.028
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 5/93 (5%)

Query: 39  PWVEKYRPKCVDEVAFQEEVVA---VLKKSLEGADLPNLLFYGPPGTGKTST--ILAAAR 93
           P  +  RP  + +   Q + V    +L+  LE  ++P+L+ +GPPG GKT+   I+A+  
Sbjct: 226 PLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIASNS 285

Query: 94  ELFGPELFRLRVLELNASDERGIQVVREKVKNF 126
           +        L       +D R +    +  K+F
Sbjct: 286 KKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSF 318


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score = 35.4 bits (80), Expect = 0.080
 Identities = 43/188 (22%), Positives = 73/188 (38%), Gaps = 45/188 (23%)

Query: 74  LLFYGPPGTGKTSTILAAARE-------LFGPELFRLRVLELNASDERGIQVVREKVKNF 126
           +LFYGPPG GKT    A A E       + GPEL  +   E     E  ++ + +K +  
Sbjct: 514 VLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGE----SEANVREIFDKARQA 569

Query: 127 AQLTVSGSRSDGKPCPPFKIVILDEADSMT-----------SAAQAALRRTMEK----ES 171
           A            PC    ++  DE DS+             AA   + + + +     +
Sbjct: 570 A------------PC----VLFFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMST 613

Query: 172 KTTRFCLICNYVSRIIEPL---TSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIA 228
           K   F +       II+P      R  +  + PL D+  +  +L    +++    D  + 
Sbjct: 614 KKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLE 673

Query: 229 YLVKVSEG 236
           +L K++ G
Sbjct: 674 FLAKMTNG 681



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 7/34 (20%)

Query: 74  LLFYGPPGTGKTSTILAAARE-------LFGPEL 100
           +L YGPPGTGKT    A A E       + GPE+
Sbjct: 241 ILLYGPPGTGKTLIARAVANETGAFFFLINGPEI 274


>gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]
          Length = 1844

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 10/71 (14%)

Query: 74   LLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFA---QLT 130
            +L  GP G GKT+ + A A+EL        ++ E+NAS +R  + +  ++K      Q+ 
Sbjct: 1128 VLITGPTGVGKTAAVYACAQEL------GFKIFEVNASSQRSGRQILSQLKEATQSHQVD 1181

Query: 131  VSGSRSDGKPC 141
              G  S  KPC
Sbjct: 1182 KQGVNSQ-KPC 1191


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 42/158 (26%), Positives = 65/158 (41%), Gaps = 38/158 (24%)

Query: 14  PPLTKDRGVAASAGSSGENKK--AKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADL 71
           P L +D G A     +  ++   A  +P V  +    + EV  ++E++  ++  LE  +L
Sbjct: 673 PLLAEDFGQALEQLQTAHSQAVGAPKIPSVSWHDVGGLQEV--KKEILETIQLPLEHPEL 730

Query: 72  -------PNLLFYGPPGTGKTSTILAAARE-------LFGPELFRLRVLELNASDERGIQ 117
                    LL +GPPGTGKT    A A E       + GPEL  + V       E  ++
Sbjct: 731 LSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYV----GQSEENVR 786

Query: 118 VVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSM 155
            V  + +  A            PC    I+  DE DS+
Sbjct: 787 EVFARARAAA------------PC----IIFFDELDSL 808



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 12/92 (13%)

Query: 37  PVPWVEKYRPKCVDEV------AFQEEVVAVLKKSLE--GADLP---NLLFYGPPGTGKT 85
           PVPW+          +      A   E+ AVLK  L+  GA L    ++L  GPPG GKT
Sbjct: 418 PVPWLPSEESTLWSSLSPPGLEALVSELCAVLKPRLQPGGALLTGTSSVLLRGPPGCGKT 477

Query: 86  STILAAARELFGPELFRLRVLELNASDERGIQ 117
            T++AAA    G  L ++    L A     ++
Sbjct: 478 -TVVAAACSHLGLHLLKVPCSSLCAESSGAVE 508


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 27/89 (30%)

Query: 74  LLFYGPPGTGKTSTILAAARE-------LFGPELFRLRVLELNASDERGIQVVREKVKNF 126
           +L  GPPG GKT    A A E       + GPEL  + V E     ER ++ V ++ KN 
Sbjct: 512 VLLAGPPGCGKTLLAKAVANESGLNFISVKGPELLNMYVGE----SERAVRQVFQRAKNS 567

Query: 127 AQLTVSGSRSDGKPCPPFKIVILDEADSM 155
           A            PC    ++  DE D++
Sbjct: 568 A------------PC----VIFFDEVDAL 580



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 17/91 (18%)

Query: 74  LLFYGPPGTGKTSTILAAARELFGPELFRLRVLEL--NASDERGIQVVREKVKNFAQLTV 131
           +L +GPPG GKT    A A EL  P + ++   E+    S E       +K++   +  V
Sbjct: 195 VLLHGPPGCGKTLLAHAIAGELDLP-ILKVAAPEIVSGVSGES-----EQKLRELFEQAV 248

Query: 132 SGSRSDGKPCPPFKIVILDEADSMTSAAQAA 162
           S +     PC    I+ +DE D++T   + A
Sbjct: 249 SNA-----PC----IIFIDEIDAITPKREVA 270


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 27/89 (30%)

Query: 74  LLFYGPPGTGKTSTILAAARE-------LFGPELFRLRVLELNASDERGIQVVREKVKNF 126
           +L  GPPG GKT    A A E       + GPEL  + V E     ER ++ V ++ KN 
Sbjct: 618 VLLAGPPGCGKTLLAKAVANESGLNFISVKGPELLNMYVGE----SERAVRQVFQRAKNS 673

Query: 127 AQLTVSGSRSDGKPCPPFKIVILDEADSM 155
           A            PC    ++  DE D++
Sbjct: 674 A------------PC----VIFFDEVDAL 686



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 17/91 (18%)

Query: 74  LLFYGPPGTGKTSTILAAARELFGPELFRLRVLEL--NASDERGIQVVREKVKNFAQLTV 131
           +L +GPPG GKT    A A EL  P + ++   E+    S E       +K++   +  V
Sbjct: 301 VLLHGPPGCGKTLLAHAIAGELDLP-ILKVAAPEIVSGVSGES-----EQKLRELFEQAV 354

Query: 132 SGSRSDGKPCPPFKIVILDEADSMTSAAQAA 162
           S +     PC    I+ +DE D++T   + A
Sbjct: 355 SNA-----PC----IIFIDEIDAITPKREVA 376


>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
          Length = 773

 Score = 33.9 bits (76), Expect = 0.23
 Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 18/105 (17%)

Query: 56  EEVVAVLKK----SLEGADLPN-LLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNA 110
           +EVV  LK     ++ G  LP  +L  GPPGTGKT    A A E   P  +       + 
Sbjct: 352 QEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYY----ASGSE 407

Query: 111 SDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSM 155
            DE  + V   +++N  +   + +     PC    ++ +DE DS+
Sbjct: 408 FDEMFVGVGASRIRNLFREAKANA-----PC----VIFIDELDSV 443


>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
          Length = 716

 Score = 33.9 bits (76), Expect = 0.23
 Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 18/105 (17%)

Query: 56  EEVVAVLKK----SLEGADLPN-LLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNA 110
           +EVV  LK     ++ G  LP  +L  GPPGTGKT    A A E   P  +       + 
Sbjct: 295 QEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYY----ASGSE 350

Query: 111 SDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSM 155
            DE  + V   +++N  +   + +     PC    ++ +DE DS+
Sbjct: 351 FDEMFVGVGASRIRNLFREAKANA-----PC----VIFIDELDSV 386


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,911,479
Number of Sequences: 37866
Number of extensions: 533813
Number of successful extensions: 1781
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 1683
Number of HSP's gapped (non-prelim): 119
length of query: 363
length of database: 18,247,518
effective HSP length: 104
effective length of query: 259
effective length of database: 14,309,454
effective search space: 3706148586
effective search space used: 3706148586
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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