Guide to the Human Genome
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Search of human proteins with 4506381

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
sapiens]
         (192 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi...   393   e-110
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra...   369   e-102
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil...   359   e-100
gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra...   357   3e-99
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]           279   9e-76
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]           276   6e-75
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]            276   6e-75
gi|46249393 ras homolog gene family, member G [Homo sapiens]          275   2e-74
gi|50263042 ras-like protein TC10 [Homo sapiens]                      244   4e-65
gi|16903164 ras homolog gene family, member J [Homo sapiens]          232   2e-61
gi|11034843 ras homolog gene family, member U [Homo sapiens]          218   3e-57
gi|111494251 ras homolog gene family, member C precursor [Homo s...   210   5e-55
gi|111494248 ras homolog gene family, member C precursor [Homo s...   210   5e-55
gi|28395033 ras homolog gene family, member C precursor [Homo sa...   210   5e-55
gi|10835049 ras homolog gene family, member A [Homo sapiens]          208   3e-54
gi|229577148 ras homolog gene family, member V [Homo sapiens]         206   1e-53
gi|4757764 ras homolog gene family, member B [Homo sapiens]           206   1e-53
gi|38016957 ras homolog gene family, member F [Homo sapiens]          197   3e-51
gi|7656900 ras homolog D [Homo sapiens]                               192   1e-49
gi|4885581 Rho family GTPase 2 [Homo sapiens]                         167   7e-42
gi|4885069 ras homolog gene family, member E [Homo sapiens]           162   2e-40
gi|4757770 ras homolog gene family, member H [Homo sapiens]           156   1e-38
gi|7657514 GTP-binding protein RHO6 [Homo sapiens]                    149   2e-36
gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo...   126   1e-29
gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo...   126   1e-29
gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo...   126   1e-29
gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]        126   1e-29
gi|5902050 Ras-like without CAAX 1 [Homo sapiens]                      92   3e-19
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]        91   6e-19
gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]        88   4e-18

>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
           sapiens]
          Length = 192

 Score =  393 bits (1009), Expect = e-110
 Identities = 192/192 (100%), Positives = 192/192 (100%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
           MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120
           QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR
Sbjct: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120

Query: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180
           DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ
Sbjct: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180

Query: 181 PTRQQKRACSLL 192
           PTRQQKRACSLL
Sbjct: 181 PTRQQKRACSLL 192


>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
           [Homo sapiens]
          Length = 192

 Score =  369 bits (946), Expect = e-102
 Identities = 177/192 (92%), Positives = 185/192 (96%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
           MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAG
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120
           QEDYDRLRPLSYPQTDVFLICFSLVSPAS+ENVRAKW+PEVRHHCP+TPIILVGTKLDLR
Sbjct: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR 120

Query: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180
           DDKDTIEKLKEKKL PITYPQGLA+AKEI +VKYLECSALTQRGLKTVFDEAIRAVLCP 
Sbjct: 121 DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP 180

Query: 181 PTRQQKRACSLL 192
           P +++KR C LL
Sbjct: 181 PVKKRKRKCLLL 192


>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
           small GTP binding protein Rac3) [Homo sapiens]
          Length = 192

 Score =  359 bits (921), Expect = e-100
 Identities = 170/191 (89%), Positives = 183/191 (95%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
           MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAG
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120
           QEDYDRLRPLSYPQTDVFLICFSLVSPAS+ENVRAKW+PEVRHHCP TPI+LVGTKLDLR
Sbjct: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLR 120

Query: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180
           DDKDTIE+L++KKLAPITYPQGLA+A+EI SVKYLECSALTQRGLKTVFDEAIRAVLCP 
Sbjct: 121 DDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPP 180

Query: 181 PTRQQKRACSL 191
           P ++  + C++
Sbjct: 181 PVKKPGKKCTV 191


>gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b
           [Homo sapiens]
          Length = 211

 Score =  357 bits (916), Expect = 3e-99
 Identities = 177/211 (83%), Positives = 185/211 (87%), Gaps = 19/211 (9%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
           MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAG
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60

Query: 61  QEDYDRLRPLSYPQT-------------------DVFLICFSLVSPASYENVRAKWFPEV 101
           QEDYDRLRPLSYPQT                   DVFLICFSLVSPAS+ENVRAKW+PEV
Sbjct: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120

Query: 102 RHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALT 161
           RHHCP+TPIILVGTKLDLRDDKDTIEKLKEKKL PITYPQGLA+AKEI +VKYLECSALT
Sbjct: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180

Query: 162 QRGLKTVFDEAIRAVLCPQPTRQQKRACSLL 192
           QRGLKTVFDEAIRAVLCP P +++KR C LL
Sbjct: 181 QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211


>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
          Length = 191

 Score =  279 bits (714), Expect = 9e-76
 Identities = 130/189 (68%), Positives = 154/189 (81%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
           MQ IKCVVVGDGAVGKTCLLISYTTN FP EY+PTVFDNY+  VM+  +P  LGL+DTAG
Sbjct: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 60

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120
           QEDYDRLRPLSYPQTDVFL+CFS+VSP+S+ENV+ KW PE+ HHCP TP +LVGT++DLR
Sbjct: 61  QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 120

Query: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180
           DD  TIEKL + K  PIT      LA+++ +VKY+ECSALTQRGLK VFDEAI A L P 
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALEPP 180

Query: 181 PTRQQKRAC 189
            T+ +++ C
Sbjct: 181 ETQPKRKCC 189


>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  276 bits (707), Expect = 6e-75
 Identities = 132/192 (68%), Positives = 155/192 (80%), Gaps = 1/192 (0%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
           MQ IKCVVVGDGAVGKTCLLISYTTN FP EY+PTVFDNY+  VM+  +P  LGL+DTAG
Sbjct: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 60

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120
           QEDYDRLRPLSYPQTDVFL+CFS+VSP+S+ENV+ KW PE+ HHCP TP +LVGT++DLR
Sbjct: 61  QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 120

Query: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180
           DD  TIEKL + K  PIT      LA+++ +VKY+ECSALTQ+GLK VFDEAI A L P 
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEP- 179

Query: 181 PTRQQKRACSLL 192
           P  ++ R C LL
Sbjct: 180 PEPKKSRRCVLL 191


>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  276 bits (707), Expect = 6e-75
 Identities = 132/192 (68%), Positives = 155/192 (80%), Gaps = 1/192 (0%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
           MQ IKCVVVGDGAVGKTCLLISYTTN FP EY+PTVFDNY+  VM+  +P  LGL+DTAG
Sbjct: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 60

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120
           QEDYDRLRPLSYPQTDVFL+CFS+VSP+S+ENV+ KW PE+ HHCP TP +LVGT++DLR
Sbjct: 61  QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 120

Query: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180
           DD  TIEKL + K  PIT      LA+++ +VKY+ECSALTQ+GLK VFDEAI A L P 
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEP- 179

Query: 181 PTRQQKRACSLL 192
           P  ++ R C LL
Sbjct: 180 PEPKKSRRCVLL 191


>gi|46249393 ras homolog gene family, member G [Homo sapiens]
          Length = 191

 Score =  275 bits (703), Expect = 2e-74
 Identities = 137/192 (71%), Positives = 155/192 (80%), Gaps = 1/192 (0%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
           MQ+IKCVVVGDGAVGKTCLLI YTTNAFP EYIPTVFDNYSA   VD + VNL LWDTAG
Sbjct: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120
           QE+YDRLR LSYPQT+VF+ICFS+ SP SYENVR KW PEV HHCP  PI+LVGTK DLR
Sbjct: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120

Query: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180
              DT+ +LKE+  APIT  QG ALAK+I +V+YLECSAL Q G+K VF EA+RAVL P 
Sbjct: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 180

Query: 181 PTRQQKRACSLL 192
           P + + R+C LL
Sbjct: 181 PIK-RGRSCILL 191


>gi|50263042 ras-like protein TC10 [Homo sapiens]
          Length = 205

 Score =  244 bits (622), Expect = 4e-65
 Identities = 115/184 (62%), Positives = 146/184 (79%)

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQED 63
           +KCVVVGDGAVGKTCLL+SY  +AFP EY+PTVFD+Y+ +V V  K   LGL+DTAGQED
Sbjct: 10  LKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQED 69

Query: 64  YDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDK 123
           YDRLRPLSYP TDVFLICFS+V+PAS++NV+ +W PE++ + P+ P +L+GT++DLRDD 
Sbjct: 70  YDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDP 129

Query: 124 DTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTR 183
            T+ +L + K  PI   QG  LAKEI +  Y+ECSALTQ+GLKTVFDEAI A+L P+   
Sbjct: 130 KTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHT 189

Query: 184 QQKR 187
            +KR
Sbjct: 190 VKKR 193


>gi|16903164 ras homolog gene family, member J [Homo sapiens]
          Length = 214

 Score =  232 bits (591), Expect = 2e-61
 Identities = 112/187 (59%), Positives = 142/187 (75%), Gaps = 3/187 (1%)

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQED 63
           +KCVVVGDGAVGKTCLL+SY  +AFP EY+PTVFD+Y+  V V  K   LGL+DTAGQED
Sbjct: 22  LKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQED 81

Query: 64  YDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDK 123
           Y++LRPLSYP TDVFLICFS+V+PASY NV+ +W PE++   P  P +L+GT++DLRDD 
Sbjct: 82  YNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDP 141

Query: 124 DTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTR 183
            T+ +L   K  P+TY  G+ LAK I +  YLECSALTQ+GLK VFDEAI  +  P   +
Sbjct: 142 KTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHP---K 198

Query: 184 QQKRACS 190
           ++K+ CS
Sbjct: 199 KKKKRCS 205


>gi|11034843 ras homolog gene family, member U [Homo sapiens]
          Length = 258

 Score =  218 bits (554), Expect = 3e-57
 Identities = 104/186 (55%), Positives = 136/186 (73%)

Query: 2   QAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQ 61
           + +KCV+VGDGAVGKT L++SYTTN +P EYIPT FDN+SA V VD +PV L L DTAGQ
Sbjct: 48  RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQ 107

Query: 62  EDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRD 121
           +++D+LRPL Y  TD+FL+CFS+VSP+S++NV  KW PE+R HCP  PIILVGT+ DLR+
Sbjct: 108 DEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLRE 167

Query: 122 DKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQP 181
           D   + +L + K  P+        A+EI +  Y+ECSALTQ+ LK VFD AI A +    
Sbjct: 168 DVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSD 227

Query: 182 TRQQKR 187
           T+QQ +
Sbjct: 228 TQQQPK 233


>gi|111494251 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  210 bits (535), Expect = 5e-55
 Identities = 103/188 (54%), Positives = 132/188 (70%), Gaps = 1/188 (0%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDY 64
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K V L LWDTAGQEDY
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKD 124
           DRLRPLSYP TDV L+CFS+ SP S EN+  KW PEV+H CP+ PIILVG K DLR D+ 
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEH 126

Query: 125 TIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQ 184
           T  +L + K  P+   +G  +A  I +  YLECSA T+ G++ VF+ A RA L  +  + 
Sbjct: 127 TRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNK- 185

Query: 185 QKRACSLL 192
           ++R C +L
Sbjct: 186 RRRGCPIL 193


>gi|111494248 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  210 bits (535), Expect = 5e-55
 Identities = 103/188 (54%), Positives = 132/188 (70%), Gaps = 1/188 (0%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDY 64
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K V L LWDTAGQEDY
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKD 124
           DRLRPLSYP TDV L+CFS+ SP S EN+  KW PEV+H CP+ PIILVG K DLR D+ 
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEH 126

Query: 125 TIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQ 184
           T  +L + K  P+   +G  +A  I +  YLECSA T+ G++ VF+ A RA L  +  + 
Sbjct: 127 TRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNK- 185

Query: 185 QKRACSLL 192
           ++R C +L
Sbjct: 186 RRRGCPIL 193


>gi|28395033 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  210 bits (535), Expect = 5e-55
 Identities = 103/188 (54%), Positives = 132/188 (70%), Gaps = 1/188 (0%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDY 64
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K V L LWDTAGQEDY
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKD 124
           DRLRPLSYP TDV L+CFS+ SP S EN+  KW PEV+H CP+ PIILVG K DLR D+ 
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEH 126

Query: 125 TIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQ 184
           T  +L + K  P+   +G  +A  I +  YLECSA T+ G++ VF+ A RA L  +  + 
Sbjct: 127 TRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNK- 185

Query: 185 QKRACSLL 192
           ++R C +L
Sbjct: 186 RRRGCPIL 193


>gi|10835049 ras homolog gene family, member A [Homo sapiens]
          Length = 193

 Score =  208 bits (529), Expect = 3e-54
 Identities = 103/188 (54%), Positives = 133/188 (70%), Gaps = 2/188 (1%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDY 64
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K V L LWDTAGQEDY
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKD 124
           DRLRPLSYP TDV L+CFS+ SP S EN+  KW PEV+H CP+ PIILVG K DLR+D+ 
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126

Query: 125 TIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQ 184
           T  +L + K  P+   +G  +A  I +  Y+ECSA T+ G++ VF+ A RA L  Q  R 
Sbjct: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL--QARRG 184

Query: 185 QKRACSLL 192
           +K++  L+
Sbjct: 185 KKKSGCLV 192


>gi|229577148 ras homolog gene family, member V [Homo sapiens]
          Length = 236

 Score =  206 bits (524), Expect = 1e-53
 Identities = 96/175 (54%), Positives = 126/175 (72%), Gaps = 1/175 (0%)

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQED 63
           IKCV+VGDGAVGK+ L++SYT N +P  Y PT  D +S  V+VD  PV + LWDTAGQED
Sbjct: 32  IKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQED 91

Query: 64  YDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDK 123
           +DRLR L YP TDVFL CFS+V P+S++N+  KW PE+R H P  P++LVGT+ DLRDD 
Sbjct: 92  FDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDV 151

Query: 124 DTIEKLKE-KKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVL 177
           + + +L +  +  P+  PQ   LA++I +  YLECSALTQ+ LK VFD AI + +
Sbjct: 152 NVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAI 206


>gi|4757764 ras homolog gene family, member B [Homo sapiens]
          Length = 196

 Score =  206 bits (523), Expect = 1e-53
 Identities = 100/173 (57%), Positives = 121/173 (69%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDY 64
           K VVVGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K V L LWDTAGQEDY
Sbjct: 7   KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKD 124
           DRLRPLSYP TDV L+CFS+ SP S EN+  KW PEV+H CP+ PIILV  K DLR D+ 
Sbjct: 67  DRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEH 126

Query: 125 TIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVL 177
              +L   K  P+    G A+A  I +  YLECSA T+ G++ VF+ A RA L
Sbjct: 127 VRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAAL 179


>gi|38016957 ras homolog gene family, member F [Homo sapiens]
          Length = 211

 Score =  197 bits (502), Expect = 3e-51
 Identities = 97/191 (50%), Positives = 130/191 (68%), Gaps = 2/191 (1%)

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQED 63
           +K V+VGDG  GKT LL+ Y+  +FP  Y P+VF+ Y+A+V V SK V L L+DTAGQED
Sbjct: 20  LKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQED 79

Query: 64  YDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDK 123
           YDRLRPLSY  T + LIC+ +++P SY+NV  KWFPEV H C   P++L+G K DLR DK
Sbjct: 80  YDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDK 139

Query: 124 DTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVL--CPQP 181
           + + KL+  +L PITY QGL+  ++I +  YLECSA  +  ++ VF EA +  L    + 
Sbjct: 140 EQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKA 199

Query: 182 TRQQKRACSLL 192
            RQ+KR   LL
Sbjct: 200 QRQKKRRLCLL 210


>gi|7656900 ras homolog D [Homo sapiens]
          Length = 210

 Score =  192 bits (488), Expect = 1e-49
 Identities = 87/177 (49%), Positives = 116/177 (65%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
           ++++K V+VGDG  GKT LL+ +   AFP  Y PTVF+ Y  N+ V  KPV+L +WDTAG
Sbjct: 15  VRSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDTAG 74

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120
           Q+DYDRLRPL YP   V L+CF + SP S++N+  +W+PEV H C   PII+VG K DLR
Sbjct: 75  QDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLR 134

Query: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVL 177
            DK  + KL+   L P+TY +G  +A+ + +V YLECSA     +  VF EA    L
Sbjct: 135 KDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHDNVHAVFQEAAEVAL 191


>gi|4885581 Rho family GTPase 2 [Homo sapiens]
          Length = 227

 Score =  167 bits (422), Expect = 7e-42
 Identities = 76/174 (43%), Positives = 116/174 (66%), Gaps = 1/174 (0%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDY 64
           K VVVGD   GKT LL  +  +A+PG Y+PTVF+NY+A+  +D + + L +WDT+G   Y
Sbjct: 9   KIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYY 68

Query: 65  DRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKD 124
           D +RPL+YP +D  LICF +  P + ++V  KW  E +  CP+  ++LVG KLD+R D  
Sbjct: 69  DNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLA 128

Query: 125 TIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSA-LTQRGLKTVFDEAIRAVL 177
           T+ +L +++L P+T+ QG  LAK++ +V Y+ECS+  ++R ++ VF  A  A L
Sbjct: 129 TLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASL 182


>gi|4885069 ras homolog gene family, member E [Homo sapiens]
          Length = 244

 Score =  162 bits (409), Expect = 2e-40
 Identities = 77/177 (43%), Positives = 114/177 (64%), Gaps = 3/177 (1%)

Query: 2   QAIKC--VVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTA 59
           Q +KC  VVVGD   GKT LL  +  + FP  Y+PTVF+NY+A+  +D++ + L LWDT+
Sbjct: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79

Query: 60  GQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDL 119
           G   YD +RPLSYP +D  LICF +  P + ++V  KW  E++  CP+T ++LVG K DL
Sbjct: 80  GSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDL 139

Query: 120 RDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSAL-TQRGLKTVFDEAIRA 175
           R D  T+ +L   +  P++Y QG  +AK+I +  Y+ECSAL ++  ++ +F  A  A
Sbjct: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLA 196


>gi|4757770 ras homolog gene family, member H [Homo sapiens]
          Length = 191

 Score =  156 bits (394), Expect = 1e-38
 Identities = 75/191 (39%), Positives = 122/191 (63%), Gaps = 7/191 (3%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
           + +IKCV+VGD AVGKT LL+ +T+  FP  Y PTV++N   +V +D   ++LGLWDTAG
Sbjct: 2   LSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAG 61

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120
            + +  +RPLSY Q DV L+C+S+ +  S+ N++ KW  E+R + P TP+++V T+ D R
Sbjct: 62  NDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQR 121

Query: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180
           +       +   + + +   +G  LA+++ +  YLECSAL+ RG++ VF+ A+R  +   
Sbjct: 122 E-------MGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQA 174

Query: 181 PTRQQKRACSL 191
             R ++R  S+
Sbjct: 175 RRRNRRRLFSI 185


>gi|7657514 GTP-binding protein RHO6 [Homo sapiens]
          Length = 232

 Score =  149 bits (375), Expect = 2e-36
 Identities = 77/191 (40%), Positives = 116/191 (60%), Gaps = 6/191 (3%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDY 64
           K V+VGD   GKT +L     + +P  Y+PTVF+NY+A +  + + V L LWDT+G   Y
Sbjct: 15  KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74

Query: 65  DRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKD 124
           D +RPL Y  +D  L+CF +  P + ++   KW  E+  +CPST ++L+G K DLR D  
Sbjct: 75  DNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLS 134

Query: 125 TIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALT-QRGLKTVFDEAIRAVLC---PQ 180
           T+ +L  +K API+Y QG A+AK++ +  YLE SA T ++ + ++F  A  ++LC   P 
Sbjct: 135 TLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTA--SMLCLNKPS 192

Query: 181 PTRQQKRACSL 191
           P  Q+    SL
Sbjct: 193 PLPQKSPVRSL 203


>gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 727

 Score =  126 bits (317), Expect = 1e-29
 Identities = 78/200 (39%), Positives = 114/200 (57%), Gaps = 26/200 (13%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44
           ++ IKCVVVGD AVGKT L+ +   NA   +Y      +PTV+  D Y         +  
Sbjct: 12  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71

Query: 45  MVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHH 104
           +VD   V+L LWDT G  D+ + R  +Y ++DV ++CFS+ +P S  +V+  W+PE++H 
Sbjct: 72  VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 129

Query: 105 CPSTPIILVGTKLDLR-DDKDTIEKLKEKKLAPI------TYPQGLALAKEIDSVKYLEC 157
           CP  P+ILVG +LDLR  D + + + +     PI         +G  +AKE+  + Y E 
Sbjct: 130 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 188

Query: 158 SALTQRGLKTVFDEAIRAVL 177
           S + Q G+K VFD AIRA L
Sbjct: 189 SVVAQFGIKDVFDNAIRAAL 208


>gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 734

 Score =  126 bits (317), Expect = 1e-29
 Identities = 78/200 (39%), Positives = 114/200 (57%), Gaps = 26/200 (13%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44
           ++ IKCVVVGD AVGKT L+ +   NA   +Y      +PTV+  D Y         +  
Sbjct: 19  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 78

Query: 45  MVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHH 104
           +VD   V+L LWDT G  D+ + R  +Y ++DV ++CFS+ +P S  +V+  W+PE++H 
Sbjct: 79  VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 136

Query: 105 CPSTPIILVGTKLDLR-DDKDTIEKLKEKKLAPI------TYPQGLALAKEIDSVKYLEC 157
           CP  P+ILVG +LDLR  D + + + +     PI         +G  +AKE+  + Y E 
Sbjct: 137 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 195

Query: 158 SALTQRGLKTVFDEAIRAVL 177
           S + Q G+K VFD AIRA L
Sbjct: 196 SVVAQFGIKDVFDNAIRAAL 215


>gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 749

 Score =  126 bits (317), Expect = 1e-29
 Identities = 78/200 (39%), Positives = 114/200 (57%), Gaps = 26/200 (13%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44
           ++ IKCVVVGD AVGKT L+ +   NA   +Y      +PTV+  D Y         +  
Sbjct: 34  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 93

Query: 45  MVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHH 104
           +VD   V+L LWDT G  D+ + R  +Y ++DV ++CFS+ +P S  +V+  W+PE++H 
Sbjct: 94  VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 151

Query: 105 CPSTPIILVGTKLDLR-DDKDTIEKLKEKKLAPI------TYPQGLALAKEIDSVKYLEC 157
           CP  P+ILVG +LDLR  D + + + +     PI         +G  +AKE+  + Y E 
Sbjct: 152 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 210

Query: 158 SALTQRGLKTVFDEAIRAVL 177
           S + Q G+K VFD AIRA L
Sbjct: 211 SVVAQFGIKDVFDNAIRAAL 230


>gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]
          Length = 696

 Score =  126 bits (316), Expect = 1e-29
 Identities = 78/200 (39%), Positives = 114/200 (57%), Gaps = 26/200 (13%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44
           ++ IKCVVVGD AVGKT L+ +   N    +Y      +PTV+  D Y         +  
Sbjct: 12  VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71

Query: 45  MVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHH 104
           +VD   V+L LWDT G  D+ + R  +Y ++DV ++CFS+ +P S  +V++ W+PE++H 
Sbjct: 72  VVDEVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHF 129

Query: 105 CPSTPIILVGTKLDLR-DDKDTIEKLKEKKLAPITY------PQGLALAKEIDSVKYLEC 157
           CP TP+ILVG +LDLR  D + + + +     PI         +G  +AKE+  + Y E 
Sbjct: 130 CPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYET 188

Query: 158 SALTQRGLKTVFDEAIRAVL 177
           S   Q G+K VFD AIRA L
Sbjct: 189 SVFDQFGIKDVFDNAIRAAL 208


>gi|5902050 Ras-like without CAAX 1 [Homo sapiens]
          Length = 219

 Score = 92.0 bits (227), Expect = 3e-19
 Identities = 55/173 (31%), Positives = 89/173 (51%), Gaps = 14/173 (8%)

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDY 64
           K V++G G VGK+ + + + ++ FP ++ PT+ D Y   + +D +P NL + DTAGQ ++
Sbjct: 23  KLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAGQAEF 82

Query: 65  DRLRPLSYPQTDVFLICFSLVSPASYENVRA-KWFPEVRHHCPSTPIILVGTKLDLRDDK 123
             +R       + F+IC+S+    S+  VR  K           TP++LVG K DL    
Sbjct: 83  TAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSDL---- 138

Query: 124 DTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAV 176
                   K+L  +T  +GLALA+E  S  + E SA  +  +  VF   +R +
Sbjct: 139 --------KQLRQVTKEEGLALAREF-SCPFFETSAAYRYYIDDVFHALVREI 182


>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
          Length = 183

 Score = 90.9 bits (224), Expect = 6e-19
 Identities = 58/191 (30%), Positives = 97/191 (50%), Gaps = 14/191 (7%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
           M+  K VV+G G VGK+ L + + T +F  +Y PT+ D Y   + VDS P  L + DTAG
Sbjct: 1   MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVR-HHCPSTPIILVGTKLDL 119
            E +  +R L       F++ +SLV+  S+++++      +R       P+ILVG K+DL
Sbjct: 61  TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL 120

Query: 120 RDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCP 179
             +++            ++Y +G ALA+E  S  ++E SA  +  +  +F E +R +   
Sbjct: 121 EGERE------------VSYGEGKALAEEW-SCPFMETSAKNKASVDELFAEIVRQMNYA 167

Query: 180 QPTRQQKRACS 190
                 +  CS
Sbjct: 168 AQPNGDEGCCS 178


>gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
          Length = 183

 Score = 88.2 bits (217), Expect = 4e-18
 Identities = 57/191 (29%), Positives = 96/191 (50%), Gaps = 14/191 (7%)

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
           M+  K VV+G G VGK+ L + + T  F  +Y PT+ D Y   + VDS P  L + DTAG
Sbjct: 1   MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVR-HHCPSTPIILVGTKLDL 119
            E +  +R L       F++ +SLV+  S+++++      VR       P+ILVG K+DL
Sbjct: 61  TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120

Query: 120 RDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCP 179
             +++ +              +G ALA+E     ++E SA ++  +  +F E +R +   
Sbjct: 121 EPEREVMSS------------EGRALAQEW-GCPFMETSAKSKSMVDELFAEIVRQMNYS 167

Query: 180 QPTRQQKRACS 190
               +Q + C+
Sbjct: 168 SLPEKQDQCCT 178


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,574,511
Number of Sequences: 37866
Number of extensions: 321169
Number of successful extensions: 966
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 643
Number of HSP's gapped (non-prelim): 196
length of query: 192
length of database: 18,247,518
effective HSP length: 97
effective length of query: 95
effective length of database: 14,574,516
effective search space: 1384579020
effective search space used: 1384579020
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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