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Search of human proteins with 4506107
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506107 prolactin receptor [Homo sapiens]
(622 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506107 prolactin receptor [Homo sapiens] 1310 0.0
gi|4503993 growth hormone receptor precursor [Homo sapiens] 160 4e-39
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 125 9e-29
gi|27437045 colony stimulating factor 3 receptor isoform d precu... 74 4e-13
gi|24496783 colony stimulating factor 3 receptor isoform c precu... 74 4e-13
gi|27437042 colony stimulating factor 3 receptor isoform b precu... 74 4e-13
gi|4503081 colony stimulating factor 3 receptor isoform a precur... 74 4e-13
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 73 7e-13
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 73 7e-13
gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor ... 67 4e-11
gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor [... 67 4e-11
gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [H... 67 4e-11
gi|22212918 ciliary neurotrophic factor receptor preproprotein [... 63 9e-10
gi|4502931 ciliary neurotrophic factor receptor preproprotein [H... 63 9e-10
gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo sapi... 59 1e-08
gi|20070195 colony stimulating factor 2 receptor alpha chain iso... 58 2e-08
gi|238908519 colony stimulating factor 2 receptor alpha chain is... 58 2e-08
gi|238908515 colony stimulating factor 2 receptor alpha chain is... 58 2e-08
gi|27437032 colony stimulating factor 2 receptor alpha chain iso... 58 2e-08
gi|115430248 gp130-like monocyte receptor [Homo sapiens] 57 4e-08
gi|28610151 interleukin 7 receptor precursor [Homo sapiens] 56 9e-08
gi|4503591 erythropoietin receptor precursor [Homo sapiens] 56 9e-08
gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo sap... 55 2e-07
gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [H... 55 3e-07
gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [H... 55 3e-07
gi|238908521 colony stimulating factor 2 receptor alpha chain is... 53 7e-07
gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens] 53 1e-06
gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo sapi... 51 3e-06
gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo sap... 51 3e-06
gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens] 50 6e-06
>gi|4506107 prolactin receptor [Homo sapiens]
Length = 622
Score = 1310 bits (3390), Expect = 0.0
Identities = 622/622 (100%), Positives = 622/622 (100%)
Query: 1 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY 60
MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
Sbjct: 1 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY 60
Query: 61 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD 120
SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
Sbjct: 61 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD 120
Query: 121 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW 180
VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
Sbjct: 121 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW 180
Query: 181 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS 240
EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
Sbjct: 181 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS 240
Query: 241 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD 300
VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
Sbjct: 241 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD 300
Query: 301 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL 360
FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
Sbjct: 301 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL 360
Query: 361 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ 420
SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
Sbjct: 361 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ 420
Query: 421 PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE 480
PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE
Sbjct: 421 PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE 480
Query: 481 SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP 540
SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP
Sbjct: 481 SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP 540
Query: 541 ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS 600
ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS
Sbjct: 541 ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS 600
Query: 601 KCRLQLGGLDYLDPACFTHSFH 622
KCRLQLGGLDYLDPACFTHSFH
Sbjct: 601 KCRLQLGGLDYLDPACFTHSFH 622
>gi|4503993 growth hormone receptor precursor [Homo sapiens]
Length = 638
Score = 160 bits (404), Expect = 4e-39
Identities = 115/357 (32%), Positives = 175/357 (49%), Gaps = 37/357 (10%)
Query: 30 KPEIFKCRSPNKETFTCWWRP----GTD--GGLPTNYSLTYHREGETLMHECPDYITGGP 83
+P+ KCRSP +ETF+C W GT G + Y+ +E ECPDY++ G
Sbjct: 50 EPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGE 109
Query: 84 NSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDR 143
NSC+F +TS+W Y + T+ G+ DE V IVQPDPP+ L +
Sbjct: 110 NSCYFNSSFTSIWIPY--CIKLTSNGGT--VDEKCFSVDEIVQPDPPIALNWTLLNVSLT 165
Query: 144 KPY--LWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQK 201
+ + ++W P D++ GW L YE++ K +W++ T + SL ++
Sbjct: 166 GIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKE 225
Query: 202 YLVQVRCKP-DHGYWSAWSPATFIQIP--SDFTMNDTTV--WISVAVLSAVICLIIVWAV 256
Y V+VR K + G + +S ++ +P S FT + W+ + ++ + L ++ V
Sbjct: 226 YEVRVRSKQRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLI-IIFGIFGLTVMLFV 284
Query: 257 AL--KGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD-FPPTSDYEDLLVE 313
L K + I PPVP PKIKG D LL++GK EE+ + L D + P +D VE
Sbjct: 285 FLFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVE 344
Query: 314 YLEVDDSE----------DQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL 360
++E+D E D+ L S H K H + G+K D DSGR SC P +L
Sbjct: 345 FIELDIDEPDEKTEESDTDRLLSSDHEKSHSNLGVK------DGDSGRTSCCEPDIL 395
>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
Length = 422
Score = 125 bits (315), Expect = 9e-29
Identities = 83/224 (37%), Positives = 111/224 (49%), Gaps = 18/224 (8%)
Query: 15 LFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGG--LPTNYSLTYHREGETLM 72
+ +CL G LPP KP C S N + TC W PG G L TNYSL Y
Sbjct: 123 ILAGSCLYVG-LPPEKPVNISCWSKNMKDLTCRWTPGAHGETFLHTNYSLKYKLRWYGQD 181
Query: 73 HECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLE 132
+ C +Y T GP+SCH K +++ Y + V ATN++GS+ SD L +D+ +V DPP +
Sbjct: 182 NTCEEYHTVGPHSCHIPKDL-ALFTPYEIWVEATNRLGSARSDVLTLDILDVVTTDPPPD 240
Query: 133 LAV-EVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWE-IHFAGQQTE 190
+ V V ED+ W+ SPP L D F Y+IR + E + +W+ + QT
Sbjct: 241 VHVSRVGGLEDQLSVRWV--SPPALKDF---LFQAKYQIRYRVEDSVDWKVVDDVSNQTS 295
Query: 191 FKILSLHPGQKYLVQVRCKP-------DHGYWSAWSPATFIQIP 227
++ L PG Y VQVRC P G WS WS T P
Sbjct: 296 CRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTP 339
>gi|27437045 colony stimulating factor 3 receptor isoform d
precursor [Homo sapiens]
Length = 783
Score = 73.9 bits (180), Expect = 4e-13
Identities = 58/227 (25%), Positives = 101/227 (44%), Gaps = 30/227 (13%)
Query: 14 LLFLNTCLLNGQLPPGKPEIFKC-RSPNKETFTCWWRPGTDGGLPTNYSLTYHR------ 66
L L+ L PP P C + + C W PG + LPT+++L +
Sbjct: 109 LQILDQVELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQ 168
Query: 67 -EGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIV 125
+G++++ P G + C +++ +++ + V A N +G+S S +L +D +V
Sbjct: 169 TQGDSILDCVPK---DGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVV 225
Query: 126 QPDPPLELAVEVKQPEDRKP------YLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKA-A 178
+ +PP+ L PE P W W P I+ K E+R KP++ A
Sbjct: 226 KLEPPM-LRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKC-------ELRHKPQRGEA 277
Query: 179 EWEI--HFAGQQTEFKILSLHPGQKYLVQVRC--KPDHGYWSAWSPA 221
W + + ++++ L P Y +Q+RC P G+WS WSP+
Sbjct: 278 SWALVGPLPLEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPS 324
>gi|24496783 colony stimulating factor 3 receptor isoform c
precursor [Homo sapiens]
Length = 863
Score = 73.9 bits (180), Expect = 4e-13
Identities = 58/227 (25%), Positives = 101/227 (44%), Gaps = 30/227 (13%)
Query: 14 LLFLNTCLLNGQLPPGKPEIFKC-RSPNKETFTCWWRPGTDGGLPTNYSLTYHR------ 66
L L+ L PP P C + + C W PG + LPT+++L +
Sbjct: 109 LQILDQVELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQ 168
Query: 67 -EGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIV 125
+G++++ P G + C +++ +++ + V A N +G+S S +L +D +V
Sbjct: 169 TQGDSILDCVPK---DGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVV 225
Query: 126 QPDPPLELAVEVKQPEDRKP------YLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKA-A 178
+ +PP+ L PE P W W P I+ K E+R KP++ A
Sbjct: 226 KLEPPM-LRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKC-------ELRHKPQRGEA 277
Query: 179 EWEI--HFAGQQTEFKILSLHPGQKYLVQVRC--KPDHGYWSAWSPA 221
W + + ++++ L P Y +Q+RC P G+WS WSP+
Sbjct: 278 SWALVGPLPLEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPS 324
>gi|27437042 colony stimulating factor 3 receptor isoform b
precursor [Homo sapiens]
Length = 769
Score = 73.9 bits (180), Expect = 4e-13
Identities = 58/227 (25%), Positives = 101/227 (44%), Gaps = 30/227 (13%)
Query: 14 LLFLNTCLLNGQLPPGKPEIFKC-RSPNKETFTCWWRPGTDGGLPTNYSLTYHR------ 66
L L+ L PP P C + + C W PG + LPT+++L +
Sbjct: 109 LQILDQVELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQ 168
Query: 67 -EGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIV 125
+G++++ P G + C +++ +++ + V A N +G+S S +L +D +V
Sbjct: 169 TQGDSILDCVPK---DGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVV 225
Query: 126 QPDPPLELAVEVKQPEDRKP------YLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKA-A 178
+ +PP+ L PE P W W P I+ K E+R KP++ A
Sbjct: 226 KLEPPM-LRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKC-------ELRHKPQRGEA 277
Query: 179 EWEI--HFAGQQTEFKILSLHPGQKYLVQVRC--KPDHGYWSAWSPA 221
W + + ++++ L P Y +Q+RC P G+WS WSP+
Sbjct: 278 SWALVGPLPLEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPS 324
>gi|4503081 colony stimulating factor 3 receptor isoform a precursor
[Homo sapiens]
Length = 836
Score = 73.9 bits (180), Expect = 4e-13
Identities = 58/227 (25%), Positives = 101/227 (44%), Gaps = 30/227 (13%)
Query: 14 LLFLNTCLLNGQLPPGKPEIFKC-RSPNKETFTCWWRPGTDGGLPTNYSLTYHR------ 66
L L+ L PP P C + + C W PG + LPT+++L +
Sbjct: 109 LQILDQVELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQ 168
Query: 67 -EGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIV 125
+G++++ P G + C +++ +++ + V A N +G+S S +L +D +V
Sbjct: 169 TQGDSILDCVPK---DGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVV 225
Query: 126 QPDPPLELAVEVKQPEDRKP------YLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKA-A 178
+ +PP+ L PE P W W P I+ K E+R KP++ A
Sbjct: 226 KLEPPM-LRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKC-------ELRHKPQRGEA 277
Query: 179 EWEI--HFAGQQTEFKILSLHPGQKYLVQVRC--KPDHGYWSAWSPA 221
W + + ++++ L P Y +Q+RC P G+WS WSP+
Sbjct: 278 SWALVGPLPLEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPS 324
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
[Homo sapiens]
Length = 329
Score = 73.2 bits (178), Expect = 7e-13
Identities = 57/203 (28%), Positives = 92/203 (45%), Gaps = 21/203 (10%)
Query: 26 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYIT--GGP 83
LPP KP+ C + C W G + L TN++L + E H+ D P
Sbjct: 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL----KSEWATHKFADCKAKRDTP 179
Query: 84 NSCHFGKQYTSMWRTYI-MMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPED 142
SC Y++++ I + V A N +G SD + D Y V+P+PP L+ V E+
Sbjct: 180 TSCTV--DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEE 235
Query: 143 RKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWE----IHFAGQQTEFKILSLHP 198
L + W+ P++ + L Y I+ + + A+ W A ++ F + L P
Sbjct: 236 LSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
Query: 199 GQKYLVQVRCKPD--HGYWSAWS 219
+Y+ ++RC + GYWS WS
Sbjct: 292 FTEYVFRIRCMKEDGKGYWSDWS 314
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 73.2 bits (178), Expect = 7e-13
Identities = 57/203 (28%), Positives = 92/203 (45%), Gaps = 21/203 (10%)
Query: 26 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYIT--GGP 83
LPP KP+ C + C W G + L TN++L + E H+ D P
Sbjct: 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL----KSEWATHKFADCKAKRDTP 179
Query: 84 NSCHFGKQYTSMWRTYI-MMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPED 142
SC Y++++ I + V A N +G SD + D Y V+P+PP L+ V E+
Sbjct: 180 TSCTV--DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEE 235
Query: 143 RKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWE----IHFAGQQTEFKILSLHP 198
L + W+ P++ + L Y I+ + + A+ W A ++ F + L P
Sbjct: 236 LSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
Query: 199 GQKYLVQVRCKPD--HGYWSAWS 219
+Y+ ++RC + GYWS WS
Sbjct: 292 FTEYVFRIRCMKEDGKGYWSDWS 314
>gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor
[Homo sapiens]
Length = 422
Score = 67.4 bits (163), Expect = 4e-11
Identities = 59/208 (28%), Positives = 87/208 (41%), Gaps = 24/208 (11%)
Query: 27 PPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTY-----------HREGETLMHEC 75
PP +P + C++ + E F+C W P GLPT Y +Y R T C
Sbjct: 112 PPARP-VVSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPC 170
Query: 76 PDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAV 135
P G G ++ W Y + V N +G+S + L V + I++PDPP L V
Sbjct: 171 PQDPLGAARCVVHGAEF---WSQYRINVTEVNPLGAS-TRLLDVSLQSILRPDPPQGLRV 226
Query: 136 EVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWE-IHFAGQQTEFKIL 194
E R+ L W+ P + F L + ++ +P + W + AG E I
Sbjct: 227 ESVPGYPRR--LRASWTYPASWPCQP-HFLLKFRLQYRPAQHPAWSTVEPAG--LEEVIT 281
Query: 195 SLHPGQKYLVQVRCKP--DHGYWSAWSP 220
G + V+V + D G WS WSP
Sbjct: 282 DAVAGLPHAVRVSARDFLDAGTWSTWSP 309
>gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor
[Homo sapiens]
Length = 390
Score = 67.4 bits (163), Expect = 4e-11
Identities = 59/208 (28%), Positives = 87/208 (41%), Gaps = 24/208 (11%)
Query: 27 PPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTY-----------HREGETLMHEC 75
PP +P + C++ + E F+C W P GLPT Y +Y R T C
Sbjct: 112 PPARP-VVSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPC 170
Query: 76 PDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAV 135
P G G ++ W Y + V N +G+S + L V + I++PDPP L V
Sbjct: 171 PQDPLGAARCVVHGAEF---WSQYRINVTEVNPLGAS-TRLLDVSLQSILRPDPPQGLRV 226
Query: 136 EVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWE-IHFAGQQTEFKIL 194
E R+ L W+ P + F L + ++ +P + W + AG E I
Sbjct: 227 ESVPGYPRR--LRASWTYPASWPCQP-HFLLKFRLQYRPAQHPAWSTVEPAG--LEEVIT 281
Query: 195 SLHPGQKYLVQVRCKP--DHGYWSAWSP 220
G + V+V + D G WS WSP
Sbjct: 282 DAVAGLPHAVRVSARDFLDAGTWSTWSP 309
>gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 422
Score = 67.4 bits (163), Expect = 4e-11
Identities = 59/208 (28%), Positives = 87/208 (41%), Gaps = 24/208 (11%)
Query: 27 PPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTY-----------HREGETLMHEC 75
PP +P + C++ + E F+C W P GLPT Y +Y R T C
Sbjct: 112 PPARP-VVSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPC 170
Query: 76 PDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAV 135
P G G ++ W Y + V N +G+S + L V + I++PDPP L V
Sbjct: 171 PQDPLGAARCVVHGAEF---WSQYRINVTEVNPLGAS-TRLLDVSLQSILRPDPPQGLRV 226
Query: 136 EVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWE-IHFAGQQTEFKIL 194
E R+ L W+ P + F L + ++ +P + W + AG E I
Sbjct: 227 ESVPGYPRR--LRASWTYPASWPCQP-HFLLKFRLQYRPAQHPAWSTVEPAG--LEEVIT 281
Query: 195 SLHPGQKYLVQVRCKP--DHGYWSAWSP 220
G + V+V + D G WS WSP
Sbjct: 282 DAVAGLPHAVRVSARDFLDAGTWSTWSP 309
>gi|22212918 ciliary neurotrophic factor receptor preproprotein
[Homo sapiens]
Length = 372
Score = 62.8 bits (151), Expect = 9e-10
Identities = 53/204 (25%), Positives = 93/204 (45%), Gaps = 12/204 (5%)
Query: 21 LLNGQLPPGKPEIFKCRSPN-KETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI 79
LL+ LPP +P + CRS + F C W T +P +++T + ++ E +
Sbjct: 102 LLHVGLPPREP-VLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPAL 160
Query: 80 TGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQ 139
N CH + Y + ++ +N +G + + + + T IV+PDPP +
Sbjct: 161 K---NRCHIRYMHLFSTIKYKVSISVSNALGHNATAITFDEFT-IVKPDPPENVVARPVP 216
Query: 140 PEDRKPYLWIKW-SPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHP 198
R+ L + W +P T D ++ F L + +R +P +W+ T I +
Sbjct: 217 SNPRR--LEVTWQTPSTWPDPES--FPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYA 272
Query: 199 GQKYLVQVRCKPDH-GYWSAWSPA 221
G++Y++QV K + G WS WS A
Sbjct: 273 GKEYIIQVAAKDNEIGTWSDWSVA 296
>gi|4502931 ciliary neurotrophic factor receptor preproprotein [Homo
sapiens]
Length = 372
Score = 62.8 bits (151), Expect = 9e-10
Identities = 53/204 (25%), Positives = 93/204 (45%), Gaps = 12/204 (5%)
Query: 21 LLNGQLPPGKPEIFKCRSPN-KETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI 79
LL+ LPP +P + CRS + F C W T +P +++T + ++ E +
Sbjct: 102 LLHVGLPPREP-VLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPAL 160
Query: 80 TGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQ 139
N CH + Y + ++ +N +G + + + + T IV+PDPP +
Sbjct: 161 K---NRCHIRYMHLFSTIKYKVSISVSNALGHNATAITFDEFT-IVKPDPPENVVARPVP 216
Query: 140 PEDRKPYLWIKW-SPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHP 198
R+ L + W +P T D ++ F L + +R +P +W+ T I +
Sbjct: 217 SNPRR--LEVTWQTPSTWPDPES--FPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYA 272
Query: 199 GQKYLVQVRCKPDH-GYWSAWSPA 221
G++Y++QV K + G WS WS A
Sbjct: 273 GKEYIIQVAAKDNEIGTWSDWSVA 296
>gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo
sapiens]
Length = 427
Score = 58.9 bits (141), Expect = 1e-08
Identities = 60/275 (21%), Positives = 101/275 (36%), Gaps = 41/275 (14%)
Query: 27 PPGKPEI----FKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYITGG 82
P G PE +C N C W PG + TNY+L Y +H+C + G
Sbjct: 121 PEGDPESAVTELQCIWHNLSYMKCSWLPGRNTSPDTNYTLYYWHRSLEKIHQCENIFREG 180
Query: 83 PN-SCHFG--KQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQ 139
C F K S + + + + + G V +T V+PDPP +K
Sbjct: 181 QYFGCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPP-----HIKN 235
Query: 140 PEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQ------------ 187
L+++W P + L YE+ + + + + +
Sbjct: 236 LSFHNDDLYVQWENPQNFISR----CLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNV 291
Query: 188 --QTEFKILSLHPGQKYLVQVR------CKPDHGYWSAWSPATFIQIPSDFTMNDTTVWI 239
+ F + + P V++R C D WS WS I + T+ T + I
Sbjct: 292 ENTSCFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQEMSIGKKRNSTLYITMLLI 351
Query: 240 SVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGP 274
+++ I +++++ LK IFPP+P P
Sbjct: 352 VPVIVAGAIIVLLLYLKRLK-----IIIFPPIPDP 381
>gi|20070195 colony stimulating factor 2 receptor alpha chain
isoform a precursor [Homo sapiens]
Length = 400
Score = 58.2 bits (139), Expect = 2e-08
Identities = 62/260 (23%), Positives = 99/260 (38%), Gaps = 18/260 (6%)
Query: 34 FKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI--TGGPNSCHFGKQ 91
F C N + C W G Y L CP YI +G CH
Sbjct: 124 FSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNL 183
Query: 92 YTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKW 151
R Y ++ + ++G F D L +D I + +PP + V + ++W
Sbjct: 184 SGLTSRNYFLVNGTSREIGIQFFDSL-LDTKKIERFNPPSNVTVRCNTT-----HCLVRW 237
Query: 152 SPPTLIDLKTGWFTLLYEIRLKPEKAAEWE----IHFAGQ-QTEFKILSLHPGQKYLVQV 206
P K + Y++ + + I+ +G + + S P K+ V++
Sbjct: 238 KQPRTYQ-KLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKI 296
Query: 207 RCKPDHGY-WSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVT 265
R WS+WS A I+ SD N +V+I V ++ + IV K + +
Sbjct: 297 RAADVRILNWSSWSEA--IEFGSD-DGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQ 353
Query: 266 CIFPPVPGPKIKGFDAHLLE 285
+FPPVP K K D H +E
Sbjct: 354 RLFPPVPQIKDKLNDNHEVE 373
>gi|238908519 colony stimulating factor 2 receptor alpha chain
isoform g precursor [Homo sapiens]
Length = 410
Score = 58.2 bits (139), Expect = 2e-08
Identities = 62/260 (23%), Positives = 99/260 (38%), Gaps = 18/260 (6%)
Query: 34 FKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI--TGGPNSCHFGKQ 91
F C N + C W G Y L CP YI +G CH
Sbjct: 124 FSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNL 183
Query: 92 YTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKW 151
R Y ++ + ++G F D L +D I + +PP + V + ++W
Sbjct: 184 SGLTSRNYFLVNGTSREIGIQFFDSL-LDTKKIERFNPPSNVTVRCNTT-----HCLVRW 237
Query: 152 SPPTLIDLKTGWFTLLYEIRLKPEKAAEWE----IHFAGQ-QTEFKILSLHPGQKYLVQV 206
P K + Y++ + + I+ +G + + S P K+ V++
Sbjct: 238 KQPRTYQ-KLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKI 296
Query: 207 RCKPDHGY-WSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVT 265
R WS+WS A I+ SD N +V+I V ++ + IV K + +
Sbjct: 297 RAADVRILNWSSWSEA--IEFGSD-DGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQ 353
Query: 266 CIFPPVPGPKIKGFDAHLLE 285
+FPPVP K K D H +E
Sbjct: 354 RLFPPVPQIKDKLNDNHEVE 373
>gi|238908515 colony stimulating factor 2 receptor alpha chain
isoform a precursor [Homo sapiens]
Length = 400
Score = 58.2 bits (139), Expect = 2e-08
Identities = 62/260 (23%), Positives = 99/260 (38%), Gaps = 18/260 (6%)
Query: 34 FKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI--TGGPNSCHFGKQ 91
F C N + C W G Y L CP YI +G CH
Sbjct: 124 FSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNL 183
Query: 92 YTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKW 151
R Y ++ + ++G F D L +D I + +PP + V + ++W
Sbjct: 184 SGLTSRNYFLVNGTSREIGIQFFDSL-LDTKKIERFNPPSNVTVRCNTT-----HCLVRW 237
Query: 152 SPPTLIDLKTGWFTLLYEIRLKPEKAAEWE----IHFAGQ-QTEFKILSLHPGQKYLVQV 206
P K + Y++ + + I+ +G + + S P K+ V++
Sbjct: 238 KQPRTYQ-KLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKI 296
Query: 207 RCKPDHGY-WSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVT 265
R WS+WS A I+ SD N +V+I V ++ + IV K + +
Sbjct: 297 RAADVRILNWSSWSEA--IEFGSD-DGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQ 353
Query: 266 CIFPPVPGPKIKGFDAHLLE 285
+FPPVP K K D H +E
Sbjct: 354 RLFPPVPQIKDKLNDNHEVE 373
>gi|27437032 colony stimulating factor 2 receptor alpha chain
isoform a precursor [Homo sapiens]
Length = 400
Score = 58.2 bits (139), Expect = 2e-08
Identities = 62/260 (23%), Positives = 99/260 (38%), Gaps = 18/260 (6%)
Query: 34 FKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI--TGGPNSCHFGKQ 91
F C N + C W G Y L CP YI +G CH
Sbjct: 124 FSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNL 183
Query: 92 YTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKW 151
R Y ++ + ++G F D L +D I + +PP + V + ++W
Sbjct: 184 SGLTSRNYFLVNGTSREIGIQFFDSL-LDTKKIERFNPPSNVTVRCNTT-----HCLVRW 237
Query: 152 SPPTLIDLKTGWFTLLYEIRLKPEKAAEWE----IHFAGQ-QTEFKILSLHPGQKYLVQV 206
P K + Y++ + + I+ +G + + S P K+ V++
Sbjct: 238 KQPRTYQ-KLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKI 296
Query: 207 RCKPDHGY-WSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVT 265
R WS+WS A I+ SD N +V+I V ++ + IV K + +
Sbjct: 297 RAADVRILNWSSWSEA--IEFGSD-DGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQ 353
Query: 266 CIFPPVPGPKIKGFDAHLLE 285
+FPPVP K K D H +E
Sbjct: 354 RLFPPVPQIKDKLNDNHEVE 373
>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
Length = 764
Score = 57.4 bits (137), Expect = 4e-08
Identities = 53/224 (23%), Positives = 89/224 (39%), Gaps = 14/224 (6%)
Query: 4 NVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLT 63
N+ + L + + C + P KPE C ++ TC W PG + T Y++
Sbjct: 30 NLGMMWTWALWMLPSLCKFSLAALPAKPENISCVYYYRKNLTCTWSPGKETSY-TQYTVK 88
Query: 64 YHREGETLMHECPDYITGGPN--SCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDV 121
C + N SC F ++ Y + V A N G S Y +
Sbjct: 89 RTYAFGEKHDNCTTNSSTSENRASCSFFLPRITIPDNYTIEVEAENGDGVIKSHMTYWRL 148
Query: 122 TYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW- 180
I + +PP VK K + I+W P L + + L Y +R + + W
Sbjct: 149 ENIAKTEPP--KIFRVKPVLGIKRMIQIEWIKPELAPVSS---DLKYTLRFRTVNSTSWM 203
Query: 181 EIHFAGQQTE----FKILSLHPGQKYLVQVRCK-PDHGYWSAWS 219
E++FA + + + + L P +Y++ +RC + +WS WS
Sbjct: 204 EVNFAKNRKDKNQTYNLTGLQPFTEYVIALRCAVKESKFWSDWS 247
>gi|28610151 interleukin 7 receptor precursor [Homo sapiens]
Length = 459
Score = 56.2 bits (134), Expect = 9e-08
Identities = 72/290 (24%), Positives = 129/290 (44%), Gaps = 39/290 (13%)
Query: 119 VDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAA 178
+D+T IV+P+ P +L+V ++ + + ++ L K L++++ + EK
Sbjct: 121 IDLTTIVKPEAPFDLSVVYREGAND---FVVTFNTSHL--QKKYVKVLMHDVAYRQEKDE 175
Query: 179 EWEIHFAGQQTEFKILS--LHPGQKYLVQVRCKPDH---GYWSAWSPATFIQIP--SDFT 231
H T+ +L L P Y ++VR PDH G+WS WSP+ + + P ++ +
Sbjct: 176 NKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEINNSS 235
Query: 232 MNDTTVWISVAVLSAV-ICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGK-- 288
+ +++++LS + L+++ A L + ++P +P K K + HL +K +
Sbjct: 236 GEMDPILLTISILSFFSVALLVILACVLWKKRIKPIVWPSLPDHK-KTLE-HLCKKPRKN 293
Query: 289 ---SEELLSALGCQ-----DFPPTSDYEDLLVEYL--EVDDSEDQHL-MSVHSKEHPSQG 337
S S L CQ D + E L + ++++SE Q L V S PS+
Sbjct: 294 LNVSFNPESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESEKQRLGGDVQSPNCPSED 353
Query: 338 MKPTYLDPDTDSGR-------GSCDSPSLLSEK---CEEPQAN-PSTFYD 376
+ T DS +CD+P L S + C E N P + D
Sbjct: 354 VVITPESFGRDSSLTCLAGNVSACDAPILSSSRSLDCRESGKNGPHVYQD 403
>gi|4503591 erythropoietin receptor precursor [Homo sapiens]
Length = 508
Score = 56.2 bits (134), Expect = 9e-08
Identities = 65/299 (21%), Positives = 114/299 (38%), Gaps = 24/299 (8%)
Query: 31 PEIFKCRSPNKETFTCWWRPGTDGGL-PTNYSLTYHREGETL----MHECPDYITGGPNS 85
PE C + E C+W G+ P NYS +Y E E +H+ P
Sbjct: 47 PEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFW 106
Query: 86 CHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKP 145
C TS + + V A + + + + +V D P+ L + D
Sbjct: 107 CSLPTADTSSFVPLELRVTAAS---GAPRYHRVIHINEVVLLDAPVGLVARLA---DESG 160
Query: 146 YLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAE--WEIHFAGQQTEFKILSLHPGQKYL 203
++ ++W PP + + + YE+ + A + +TE + +L +Y
Sbjct: 161 HVVLRWLPPPETPMTSH---IRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYT 217
Query: 204 VQVRCKPDH----GYWSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALK 259
VR + G+WSAWS + PSD D + +L ++ L+ V A+
Sbjct: 218 FAVRARMAEPSFGGFWSAWSEPVSLLTPSDL---DPLILTLSLILVVILVLLTVLALLSH 274
Query: 260 GYSMVTCIFPPVPGPKIKGFDAHLLEKGKSE-ELLSALGCQDFPPTSDYEDLLVEYLEV 317
++ I+P +P P+ + KG + L GC + P + + + LEV
Sbjct: 275 RRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEV 333
>gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo
sapiens]
Length = 380
Score = 55.1 bits (131), Expect = 2e-07
Identities = 57/202 (28%), Positives = 83/202 (41%), Gaps = 18/202 (8%)
Query: 26 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI-TGGPN 84
+P K + C N + C W+PG L TNY+L Y EG +C DYI G N
Sbjct: 135 IPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQN 194
Query: 85 -SCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDR 143
C F S ++ + + VN +++ S + IV+P PP+ L + +
Sbjct: 195 IGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEI 254
Query: 144 KPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPE------KAAEWEIHFAGQQTEFKILSLH 197
K +KWS P L + F YEI ++ + E E + E + L
Sbjct: 255 K----LKWSIP-LGPIPARCFD--YEIEIREDDTTLVTATVENETYTLKTTNETRQLCFV 307
Query: 198 PGQKYLVQVRCKPDHGYWSAWS 219
K V + C D G WS WS
Sbjct: 308 VRSK--VNIYCS-DDGIWSEWS 326
>gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 54.7 bits (130), Expect = 3e-07
Identities = 56/241 (23%), Positives = 104/241 (43%), Gaps = 27/241 (11%)
Query: 46 CWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI--TGGPN-SCHFGKQYT-SMWRTYI- 100
C W GTD T Y L Y+R G + EC +Y T G N +C F + + S R ++
Sbjct: 155 CTWLVGTDAPEDTQYFL-YYRYG-SWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLA 212
Query: 101 MMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLK 160
++VN +++ + + + I Q +PPL + E++ L I+W P
Sbjct: 213 VLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTR-----LSIQWEKPV----- 262
Query: 161 TGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVR------CKPDHGY 214
+ + ++ +K + T I + KY VQVR C+ + G
Sbjct: 263 SAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCR-EAGL 321
Query: 215 WSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGP 274
WS WS ++ + + W + +++ + ++++ ++ K + +FPP+P P
Sbjct: 322 WSEWSQPIYVGNDEHKPLRE---WFVIVIMATICFILLILSLICKICHLWIKLFPPIPAP 378
Query: 275 K 275
K
Sbjct: 379 K 379
>gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 54.7 bits (130), Expect = 3e-07
Identities = 56/241 (23%), Positives = 104/241 (43%), Gaps = 27/241 (11%)
Query: 46 CWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI--TGGPN-SCHFGKQYT-SMWRTYI- 100
C W GTD T Y L Y+R G + EC +Y T G N +C F + + S R ++
Sbjct: 155 CTWLVGTDAPEDTQYFL-YYRYG-SWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLA 212
Query: 101 MMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLK 160
++VN +++ + + + I Q +PPL + E++ L I+W P
Sbjct: 213 VLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTR-----LSIQWEKPV----- 262
Query: 161 TGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVR------CKPDHGY 214
+ + ++ +K + T I + KY VQVR C+ + G
Sbjct: 263 SAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCR-EAGL 321
Query: 215 WSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGP 274
WS WS ++ + + W + +++ + ++++ ++ K + +FPP+P P
Sbjct: 322 WSEWSQPIYVGNDEHKPLRE---WFVIVIMATICFILLILSLICKICHLWIKLFPPIPAP 378
Query: 275 K 275
K
Sbjct: 379 K 379
>gi|238908521 colony stimulating factor 2 receptor alpha chain
isoform h [Homo sapiens]
Length = 267
Score = 53.1 bits (126), Expect = 7e-07
Identities = 59/248 (23%), Positives = 95/248 (38%), Gaps = 18/248 (7%)
Query: 46 CWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI--TGGPNSCHFGKQYTSMWRTYIMMV 103
C W G Y L CP YI +G CH R Y ++
Sbjct: 3 CTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVN 62
Query: 104 NATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGW 163
+ ++G F D L +D I + +PP + V + ++W P K +
Sbjct: 63 GTSREIGIQFFDSL-LDTKKIERFNPPSNVTVRCNTT-----HCLVRWKQPRTYQ-KLSY 115
Query: 164 FTLLYEIRLKPEKAAEWE----IHFAGQ-QTEFKILSLHPGQKYLVQVRCKPDHGY-WSA 217
Y++ + + I+ +G + + S P K+ V++R WS+
Sbjct: 116 LDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILNWSS 175
Query: 218 WSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIK 277
WS A I+ SD N +V+I V ++ + IV K + + +FPPVP K K
Sbjct: 176 WSEA--IEFGSD-DGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKDK 232
Query: 278 GFDAHLLE 285
D H +E
Sbjct: 233 LNDNHEVE 240
>gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]
Length = 862
Score = 52.8 bits (125), Expect = 1e-06
Identities = 54/218 (24%), Positives = 85/218 (38%), Gaps = 20/218 (9%)
Query: 28 PGKPEIFKCRSPNKE-TFTCWWRPGTDGGLPTNYSLTYH-REGETLMHECPDYITGGPNS 85
P +P+ C ++ T C W G D L T Y+L + T +C D +
Sbjct: 124 PEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYC---DY 180
Query: 86 CHFGKQYT--SMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDR 143
FG T S + V A N +GSS S IV+P PP ++ ++ ++
Sbjct: 181 LDFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVS 240
Query: 144 KPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWE-IHFAGQQTEFKILSLHPGQKY 202
+ L+ W L+ LL +R +P + W ++ + +L L P +Y
Sbjct: 241 RCTLY--WRDEGLV--------LLNRLRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEY 290
Query: 203 LVQVRCKPD--HGYWSAWSPATFIQIPSDFTMNDTTVW 238
Q+ K G WS WS + Q P + VW
Sbjct: 291 EFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVW 328
>gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo
sapiens]
Length = 468
Score = 51.2 bits (121), Expect = 3e-06
Identities = 47/202 (23%), Positives = 76/202 (37%), Gaps = 12/202 (5%)
Query: 26 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHR----EGETLMHECPDYITG 81
+PP +P++ R C W P + L T L + E C
Sbjct: 112 VPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
Query: 82 GPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPE 141
SC YI+ + + +GS FS I+QPDPP + V
Sbjct: 172 QKFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
Query: 142 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQ-QTEFKILSLHPGQ 200
R +L + W P + ++ L +E+R + E++ + Q I G
Sbjct: 231 PR--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
Query: 201 KYLVQVRCKPD--HGYWSAWSP 220
+++VQ+R + + G WS WSP
Sbjct: 287 RHVVQLRAQEEFGQGEWSEWSP 308
>gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo
sapiens]
Length = 365
Score = 51.2 bits (121), Expect = 3e-06
Identities = 47/202 (23%), Positives = 76/202 (37%), Gaps = 12/202 (5%)
Query: 26 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHR----EGETLMHECPDYITG 81
+PP +P++ R C W P + L T L + E C
Sbjct: 112 VPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
Query: 82 GPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPE 141
SC YI+ + + +GS FS I+QPDPP + V
Sbjct: 172 QKFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
Query: 142 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQ-QTEFKILSLHPGQ 200
R +L + W P + ++ L +E+R + E++ + Q I G
Sbjct: 231 PR--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
Query: 201 KYLVQVRCKPD--HGYWSAWSP 220
+++VQ+R + + G WS WSP
Sbjct: 287 RHVVQLRAQEEFGQGEWSEWSP 308
>gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens]
Length = 229
Score = 50.1 bits (118), Expect = 6e-06
Identities = 53/188 (28%), Positives = 79/188 (42%), Gaps = 22/188 (11%)
Query: 46 CWWR--PGTDGGLPTNYSLTYHREGETLMHECPDYI-TGGPNSCHFGKQYTSMWRTYIMM 102
C W P + P ++ TY H P T SC Y++
Sbjct: 46 CSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLN 105
Query: 103 VNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTG 162
V A + GSS S ++ +I++PDPP V + +R+ L ++W PP
Sbjct: 106 VTAVHPWGSSSSFVPFI-TEHIIKPDPPE--GVRLSPLAERQ--LQVQWEPPG------S 154
Query: 163 W-----FTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCK--PDHGYW 215
W F+L Y IR K + AA + + T F + ++ P +Y VQV + D+G
Sbjct: 155 WPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGEL 214
Query: 216 SAWS-PAT 222
S WS PAT
Sbjct: 215 SDWSLPAT 222
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,853,122
Number of Sequences: 37866
Number of extensions: 1569523
Number of successful extensions: 3368
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 3133
Number of HSP's gapped (non-prelim): 288
length of query: 622
length of database: 18,247,518
effective HSP length: 108
effective length of query: 514
effective length of database: 14,157,990
effective search space: 7277206860
effective search space used: 7277206860
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.