Search of human proteins with 4506051

Search of human proteins with 4506051

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506051 DNA primase polypeptide 1 [Homo sapiens]
         (420 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506051 DNA primase polypeptide 1 [Homo sapiens]                   869   0.0  
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    37   0.044
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    37   0.044
gi|120587023 down-regulated in metastasis [Homo sapiens]               32   1.1  
gi|89036565 PREDICTED: similar to Temporarily Assigned Gene name...    32   1.1  
gi|12025678 actinin, alpha 4 [Homo sapiens]                            32   1.1  
gi|18093112 ABT1-associated protein [Homo sapiens]                     32   1.1  
gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]            31   1.8  
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]            31   2.4  
gi|25952108 potassium voltage-gated channel delayed-rectifier pr...    30   3.1  
gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain c...    30   4.1  
gi|20270349 MIT, microtubule interacting and transport, domain c...    30   5.4  
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    29   7.0  
gi|75677376 coiled-coil domain containing 62 isoform b [Homo sap...    29   7.0  
gi|30348972 coiled-coil domain containing 62 isoform a [Homo sap...    29   7.0  
gi|156104903 myomesin 2 [Homo sapiens]                                 29   7.0  
gi|88196794 kelch-like 35 [Homo sapiens]                               29   7.0  
gi|115430110 hypothetical protein LOC153643 [Homo sapiens]             29   7.0  
gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens]      29   9.1  
gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens]      29   9.1  
gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]      29   9.1  
gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]      29   9.1  
gi|148529025 pleckstrin homology domain containing, family G (wi...    29   9.1  

>gi|4506051 DNA primase polypeptide 1 [Homo sapiens]
          Length = 420

 Score =  869 bits (2246), Expect = 0.0
 Identities = 420/420 (100%), Positives = 420/420 (100%)

Query: 1   METFDPTELPELLKLYYRRLFPYSQYYRWLNYGGVIKNYFQHREFSFTLKDDIYIRYQSF 60
           METFDPTELPELLKLYYRRLFPYSQYYRWLNYGGVIKNYFQHREFSFTLKDDIYIRYQSF
Sbjct: 1   METFDPTELPELLKLYYRRLFPYSQYYRWLNYGGVIKNYFQHREFSFTLKDDIYIRYQSF 60

Query: 61  NNQSDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRR 120
           NNQSDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRR
Sbjct: 61  NNQSDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRR 120

Query: 121 CCSSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSA 180
           CCSSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSA
Sbjct: 121 CCSSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSA 180

Query: 181 VRSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESW 240
           VRSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESW
Sbjct: 181 VRSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESW 240

Query: 241 DKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKNDKYGPWLEWEIMLQY 300
           DKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKNDKYGPWLEWEIMLQY
Sbjct: 241 DKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKNDKYGPWLEWEIMLQY 300

Query: 301 CFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAI 360
           CFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAI
Sbjct: 301 CFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAI 360

Query: 361 STNEEEKEENEAESDVKHRTRDYKKTSLAPYVKVFEHFLENLDKSRKGELLKKSDLQKDF 420
           STNEEEKEENEAESDVKHRTRDYKKTSLAPYVKVFEHFLENLDKSRKGELLKKSDLQKDF
Sbjct: 361 STNEEEKEENEAESDVKHRTRDYKKTSLAPYVKVFEHFLENLDKSRKGELLKKSDLQKDF 420


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 36.6 bits (83), Expect = 0.044
 Identities = 68/323 (21%), Positives = 135/323 (41%), Gaps = 39/323 (12%)

Query: 64   SDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGA-FQAQEKELVFDIDMTDYDDVRRCC 122
            S L + M+K+     +I A Y  R  Q   V L A  +AQ+KEL         D ++ C 
Sbjct: 920  SSLSQSMRKVQDSNAEILANY--RKGQEEIVTLHAEIKAQKKEL---------DTIQECI 968

Query: 123  SSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVR 182
                     +       +  ++ LK+    + + +  S          ++ ++K    ++
Sbjct: 969  KVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQ 1028

Query: 183  SGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESWDK 242
              + +   L++   ++++   LS K     ++  ++ +KY E   +  + + EN +   +
Sbjct: 1029 KDLRDKTVLIEKSHEMERA--LSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSE 1086

Query: 243  ILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKNDKYGPWLEWEIMLQYCF 302
            ILA+         Q   QK H  L++ E LKK  +    N+K +           +Q C+
Sbjct: 1087 ILAV---------QNLLQKQHVPLEQVEALKKSLNGTIENLKEELKS--------MQRCY 1129

Query: 303  PRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAIST 362
             +    V+K ++ LL+     + K   + +   LQ  + F+   V  I    RE +  S 
Sbjct: 1130 EKEQQTVTK-LHQLLE-----NQKNSSVPLAEHLQIKEAFEK-EVGIIKASLREKEEESQ 1182

Query: 363  NEEEKEENEAESDVKHRTRDYKK 385
            N+ E E ++ +S+V++  +  KK
Sbjct: 1183 NKME-EVSKLQSEVQNTKQALKK 1204


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 36.6 bits (83), Expect = 0.044
 Identities = 68/323 (21%), Positives = 135/323 (41%), Gaps = 39/323 (12%)

Query: 64   SDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGA-FQAQEKELVFDIDMTDYDDVRRCC 122
            S L + M+K+     +I A Y  R  Q   V L A  +AQ+KEL         D ++ C 
Sbjct: 933  SSLSQSMRKVQDSNAEILANY--RKGQEEIVTLHAEIKAQKKEL---------DTIQECI 981

Query: 123  SSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVR 182
                     +       +  ++ LK+    + + +  S          ++ ++K    ++
Sbjct: 982  KVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQ 1041

Query: 183  SGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESWDK 242
              + +   L++   ++++   LS K     ++  ++ +KY E   +  + + EN +   +
Sbjct: 1042 KDLRDKTVLIEKSHEMERA--LSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSE 1099

Query: 243  ILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKNDKYGPWLEWEIMLQYCF 302
            ILA+         Q   QK H  L++ E LKK  +    N+K +           +Q C+
Sbjct: 1100 ILAV---------QNLLQKQHVPLEQVEALKKSLNGTIENLKEELKS--------MQRCY 1142

Query: 303  PRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAIST 362
             +    V+K ++ LL+     + K   + +   LQ  + F+   V  I    RE +  S 
Sbjct: 1143 EKEQQTVTK-LHQLLE-----NQKNSSVPLAEHLQIKEAFEK-EVGIIKASLREKEEESQ 1195

Query: 363  NEEEKEENEAESDVKHRTRDYKK 385
            N+ E E ++ +S+V++  +  KK
Sbjct: 1196 NKME-EVSKLQSEVQNTKQALKK 1217


>gi|120587023 down-regulated in metastasis [Homo sapiens]
          Length = 2785

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 45/196 (22%), Positives = 75/196 (38%), Gaps = 43/196 (21%)

Query: 240 WDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKND----------KYG 289
           WD ++ L+    H+   + F K +     +EHL+K A+  +  ++ND           + 
Sbjct: 736 WDPVIELISSHAHEMENKQFWKVY-----YEHLEKAATHAEKELQNDMTDEKSVGDESWE 790

Query: 290 PWLEWEIMLQY---------CFPRLDINVSKGI--NHLLKSPFSVHPKTGRIS------- 331
              E ++   Y         C  RLD    + +    L K P  V P++  +S       
Sbjct: 791 QTQEGDVGALYHEQLALKTDCQERLDHTNFRFLLWRALTKFPERVEPRSRELSPLFLRFI 850

Query: 332 ----VPIDLQKVDQFDPFTVPTISFICRELD---AISTNEEEKEEN--EAESDVKHRTRD 382
                P DLQ     D         +  E++   A   +EE +EE   + ES  K +TR 
Sbjct: 851 NNEYYPADLQVAPTQD-LRRKGKGMVAEEIEEEPAAGDDEELEEEAVPQDESSQKKKTRR 909

Query: 383 YKKTSLAPYVKVFEHF 398
                L  +++VF  F
Sbjct: 910 AAAKQLIAHLQVFSKF 925


>gi|89036565 PREDICTED: similar to Temporarily Assigned Gene name
           family member (tag-184) [Homo sapiens]
          Length = 2785

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 45/196 (22%), Positives = 75/196 (38%), Gaps = 43/196 (21%)

Query: 240 WDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKND----------KYG 289
           WD ++ L+    H+   + F K +     +EHL+K A+  +  ++ND           + 
Sbjct: 736 WDPVIELISSHAHEMENKQFWKVY-----YEHLEKAATHAEKELQNDMTDEKSVGDESWE 790

Query: 290 PWLEWEIMLQY---------CFPRLDINVSKGI--NHLLKSPFSVHPKTGRIS------- 331
              E ++   Y         C  RLD    + +    L K P  V P++  +S       
Sbjct: 791 QTQEGDVGALYHEQLALKTDCQERLDHTNFRFLLWRALTKFPERVEPRSRELSPLFLRFI 850

Query: 332 ----VPIDLQKVDQFDPFTVPTISFICRELD---AISTNEEEKEEN--EAESDVKHRTRD 382
                P DLQ     D         +  E++   A   +EE +EE   + ES  K +TR 
Sbjct: 851 NNEYYPADLQVAPTQD-LRRKGKGMVAEEIEEEPAAGDDEELEEEAVPQDESSQKKKTRR 909

Query: 383 YKKTSLAPYVKVFEHF 398
                L  +++VF  F
Sbjct: 910 AAAKQLIAHLQVFSKF 925


>gi|12025678 actinin, alpha 4 [Homo sapiens]
          Length = 911

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 12/68 (17%)

Query: 226 YALVNQDILENKESWDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKN 285
           Y  V   I+ +K  W+K+  LVP+  H  L++  ++  N     EHL++  +   N +  
Sbjct: 611 YTTVTPQIINSK--WEKVQQLVPKRDHALLEEQSKQQSN-----EHLRRQFASQANVV-- 661

Query: 286 DKYGPWLE 293
              GPW++
Sbjct: 662 ---GPWIQ 666


>gi|18093112 ABT1-associated protein [Homo sapiens]
          Length = 851

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 3/63 (4%)

Query: 358 DAISTNEE-EKEENEAESDVKHRTRDYKKTSLAPYVKVFEHFLENLDKSRKGELLKKSDL 416
           D  S  EE E E  +AE  +     D        Y K+ EH  +NL K +K +L+KK +L
Sbjct: 691 DGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEH--QNLSKKKKKQLMKKKEL 748

Query: 417 QKD 419
            +D
Sbjct: 749 IED 751


>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
          Length = 724

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 46/205 (22%), Positives = 82/205 (40%), Gaps = 27/205 (13%)

Query: 185 IVEYLSLVKGGQD-------VKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENK 237
           I EYL+ ++G  D       + +++    KI   IRK  NI+KK  E ++    ++ E+K
Sbjct: 370 IPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRK--NIVKKCLELFS----ELAEDK 423

Query: 238 ESWDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKNDKYGPWLEWEIM 297
           E++ K      E     L+    +   + +R   L     RY  +   D+     E+   
Sbjct: 424 ENYKKFY----EAFSKNLKLGIHEDSTNRRRLSELL----RYHTSQSGDEMTSLSEYVSR 475

Query: 298 LQYCFPRLDINVSKGINHLLKSPFSVHPKTGRISV-----PIDLQKVDQFDPFTVPTISF 352
           ++     +     +    +  S F    +     V     PID   V Q   F   ++  
Sbjct: 476 MKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVS 535

Query: 353 ICRELDAISTNEEEKEENEAESDVK 377
           + +E   +  +EEEK++ E ES  K
Sbjct: 536 VTKEGLELPEDEEEKKKME-ESKAK 559


>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
          Length = 4523

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 22/94 (23%), Positives = 38/94 (40%), Gaps = 14/94 (14%)

Query: 100  QAQEKELVFDIDMTDYDDVRRCCSSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVY 159
            Q QE   +F++ + +Y  +++C     +    W ++    R ID             W  
Sbjct: 1298 QMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDN------------WTK 1345

Query: 160  SGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVK 193
            +  R +H    D  +R+ + A  S I E  SL K
Sbjct: 1346 TQWRQIHVEQMDVELRRFAKA--SSITEIWSLNK 1377


>gi|25952108 potassium voltage-gated channel delayed-rectifier
           protein S3 [Homo sapiens]
          Length = 491

 Score = 30.4 bits (67), Expect = 3.1
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 3/59 (5%)

Query: 357 LDAISTN--EEEKEENEAESDVKHRTRDYKKTSLAPYVKVFEHFLENLDKSRKGELLKK 413
           +D+  +N  +E KEEN  E D   ++ D    S      +FE  LE  D  R G+L KK
Sbjct: 113 IDSCCSNRYQERKEENH-EKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKK 170


>gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing A [Homo sapiens]
          Length = 312

 Score = 30.0 bits (66), Expect = 4.1
 Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 7/81 (8%)

Query: 307 INVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAISTNEEE 366
           ++V + I+ LL S         R+     L++ +Q +P     +S +  ++D + ++EEE
Sbjct: 142 MHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEP----RVSALEEDMDDVESSEEE 197

Query: 367 KEENEAESDV---KHRTRDYK 384
           +EE+E    V    HR R Y+
Sbjct: 198 EEEDEKLERVPSPDHRRRSYR 218


>gi|20270349 MIT, microtubule interacting and transport, domain
           containing 1 [Homo sapiens]
          Length = 249

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 16/44 (36%), Positives = 28/44 (63%), Gaps = 1/44 (2%)

Query: 182 RSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEE 225
           + GI   L ++KG +D  K+ +L EKI  ++ ++ N IKKY ++
Sbjct: 39  QEGIDLLLQVLKGTKDNTKRCNLREKISKYMDRAEN-IKKYLDQ 81


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 360 ISTNEEEKEENEAESDVKHRTRD--YKKTSLAPYVKVFEHFLENLDKSRKGELL 411
           + T EEE+EE E E D +    D   +K+  AP +K F+   E + + +  E++
Sbjct: 267 LKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMM 320


>gi|75677376 coiled-coil domain containing 62 isoform b [Homo
           sapiens]
          Length = 684

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 19/123 (15%)

Query: 166 HCWVCDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEE 225
           H   C    + L  A+R   +    +VK  QD K+K+         ++  +N +K+    
Sbjct: 176 HIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKA-------LKIEVNKLKED--- 225

Query: 226 YALVNQDILENKESWDKILALVPE--TIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNI 283
              +N+   EN E  ++I+ L  E   +HDEL  + ++     +R + L  +A   Q   
Sbjct: 226 ---LNEKTTENNEQREEIIRLKQEKSCLHDELLFTVERE----KRKDELLNIAKSKQERT 278

Query: 284 KND 286
            ++
Sbjct: 279 NSE 281


>gi|30348972 coiled-coil domain containing 62 isoform a [Homo
           sapiens]
          Length = 682

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 19/123 (15%)

Query: 166 HCWVCDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEE 225
           H   C    + L  A+R   +    +VK  QD K+K+         ++  +N +K+    
Sbjct: 176 HIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKA-------LKIEVNKLKED--- 225

Query: 226 YALVNQDILENKESWDKILALVPE--TIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNI 283
              +N+   EN E  ++I+ L  E   +HDEL  + ++     +R + L  +A   Q   
Sbjct: 226 ---LNEKTTENNEQREEIIRLKQEKSCLHDELLFTVERE----KRKDELLNIAKSKQERT 278

Query: 284 KND 286
            ++
Sbjct: 279 NSE 281


>gi|156104903 myomesin 2 [Homo sapiens]
          Length = 1465

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 8/83 (9%)

Query: 164 GVHCWVCDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKY- 222
           G  C VC + V       +     Y SLV    + K++  LSE  H  + + +++ +   
Sbjct: 65  GTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAH--LEEDVHLARSQA 122

Query: 223 ---FEEYALVNQDILENKESWDK 242
               ++YA+  Q ++E+K +W++
Sbjct: 123 RDKLDKYAI--QQMMEDKLAWER 143


>gi|88196794 kelch-like 35 [Homo sapiens]
          Length = 363

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 2/58 (3%)

Query: 154 HRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHLSEKIHPF 211
           H +W++S    +H W+   S+ K     +  +V+      GG D  +++H  E+  PF
Sbjct: 142 HDVWMFSSH--LHTWIKVASLHKGRWRHKMAVVQGQLFAVGGFDGLRRLHSVERYDPF 197


>gi|115430110 hypothetical protein LOC153643 [Homo sapiens]
          Length = 452

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 5/81 (6%)

Query: 199 KKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENK-----ESWDKILALVPETIHD 253
           K +  + EK+     K  N I    +E  L     +ENK     E  +K +    ET+ +
Sbjct: 345 KSENKMEEKLLQLSSKVENFINTQKQETQLSKVKHMENKLSKKMEQMEKQIWGELETMQN 404

Query: 254 ELQQSFQKSHNSLQRWEHLKK 274
           E Q  F+  H+SL   + ++K
Sbjct: 405 EYQSGFKSIHDSLSSLQQIQK 425


>gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens]
          Length = 1160

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 9/65 (13%)

Query: 352 FICRE--------LDAISTNEEEKEENEAESDVKHRTRD-YKKTSLAPYVKVFEHFLENL 402
           FIC E        LD  S  E+EK EN    + +       KKTSL+P  K+   +  +L
Sbjct: 678 FICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDL 737

Query: 403 DKSRK 407
           D ++K
Sbjct: 738 DLAKK 742


>gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens]
          Length = 1160

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 9/65 (13%)

Query: 352 FICRE--------LDAISTNEEEKEENEAESDVKHRTRD-YKKTSLAPYVKVFEHFLENL 402
           FIC E        LD  S  E+EK EN    + +       KKTSL+P  K+   +  +L
Sbjct: 678 FICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDL 737

Query: 403 DKSRK 407
           D ++K
Sbjct: 738 DLAKK 742


>gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]
          Length = 1196

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 9/65 (13%)

Query: 352 FICRE--------LDAISTNEEEKEENEAESDVKHRTRD-YKKTSLAPYVKVFEHFLENL 402
           FIC E        LD  S  E+EK EN    + +       KKTSL+P  K+   +  +L
Sbjct: 678 FICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDL 737

Query: 403 DKSRK 407
           D ++K
Sbjct: 738 DLAKK 742


>gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]
          Length = 1231

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 9/65 (13%)

Query: 352 FICRE--------LDAISTNEEEKEENEAESDVKHRTRD-YKKTSLAPYVKVFEHFLENL 402
           FIC E        LD  S  E+EK EN    + +       KKTSL+P  K+   +  +L
Sbjct: 713 FICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDL 772

Query: 403 DKSRK 407
           D ++K
Sbjct: 773 DLAKK 777


>gi|148529025 pleckstrin homology domain containing, family G (with
           RhoGef domain) member 4B [Homo sapiens]
          Length = 1271

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 30/143 (20%), Positives = 65/143 (45%), Gaps = 8/143 (5%)

Query: 146 LKEDFGFKHRLWVYSGRRGVHCWV-CDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHL 204
           L   F + H  W+   +R  H    C+E++  L ++  S  +      +  Q+V + +  
Sbjct: 331 LDGSFPYSHGDWICFRQRLEHFAANCEEAIIFLQNSFCS--LNTHRTPRTAQEVAELIDQ 388

Query: 205 SEKIHPFIRKSINIIKKYFEE---YALVNQDILENKESWDKILALVP--ETIHDELQQSF 259
            E +   + +   ++    E     A + ++ L  ++S D + A     + + +E+ +  
Sbjct: 389 HETMMKLVLEDPLLVSLRLEGGTVLARLRREELGTEDSRDTLEAATSLYDRVDEEVHRLV 448

Query: 260 QKSHNSLQRWEHLKKVASRYQNN 282
             S+N LQ+ EHL+++AS  + N
Sbjct: 449 LTSNNRLQQLEHLRELASLLEGN 471


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,723,232
Number of Sequences: 37866
Number of extensions: 685592
Number of successful extensions: 2618
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2606
Number of HSP's gapped (non-prelim): 32
length of query: 420
length of database: 18,247,518
effective HSP length: 105
effective length of query: 315
effective length of database: 14,271,588
effective search space: 4495550220
effective search space used: 4495550220
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.