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Search of human proteins with 4505619
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505619 paired box 7 isoform 1 [Homo sapiens]
(520 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 1066 0.0
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 1057 0.0
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 957 0.0
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 742 0.0
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 740 0.0
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 740 0.0
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 733 0.0
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 620 e-177
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 620 e-177
gi|7524356 paired box 3 isoform PAX3b [Homo sapiens] 343 2e-94
gi|6654638 paired box 3 isoform PAX3a [Homo sapiens] 343 2e-94
gi|189083681 paired box gene 6 isoform a [Homo sapiens] 257 2e-68
gi|4505615 paired box gene 6 isoform a [Homo sapiens] 257 2e-68
gi|4580424 paired box gene 6 isoform b [Homo sapiens] 247 2e-65
gi|9951920 paired box 5 [Homo sapiens] 219 6e-57
gi|34878716 paired box protein 2 isoform d [Homo sapiens] 213 3e-55
gi|34878701 paired box protein 2 isoform b [Homo sapiens] 213 3e-55
gi|34878709 paired box protein 2 isoform c [Homo sapiens] 213 3e-55
gi|7524361 paired box 8 isoform PAX8B [Homo sapiens] 206 4e-53
gi|34878699 paired box protein 2 isoform a [Homo sapiens] 204 2e-52
gi|34878703 paired box protein 2 isoform e [Homo sapiens] 204 2e-52
gi|7524363 paired box 8 isoform PAX8C [Homo sapiens] 201 1e-51
gi|7524365 paired box 8 isoform PAX8D [Homo sapiens] 200 2e-51
gi|7669542 paired box 8 isoform PAX8E [Homo sapiens] 200 2e-51
gi|5803117 paired box 8 isoform PAX8A [Homo sapiens] 200 2e-51
gi|197276661 paired box 1 [Homo sapiens] 188 1e-47
gi|7242167 paired box 9 [Homo sapiens] 186 3e-47
gi|170784824 paired box 4 [Homo sapiens] 186 4e-47
gi|24497589 aristaless related homeobox [Homo sapiens] 114 2e-25
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 112 8e-25
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 1066 bits (2756), Expect = 0.0
Identities = 520/520 (100%), Positives = 520/520 (100%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG 180
YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG
Sbjct: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG 180
Query: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH
Sbjct: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL
Sbjct: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
Query: 301 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 360
PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS
Sbjct: 301 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 360
Query: 361 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 420
YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS
Sbjct: 361 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 420
Query: 421 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSECLVPWASPVPI 480
ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSECLVPWASPVPI
Sbjct: 421 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSECLVPWASPVPI 480
Query: 481 PSPTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT 520
PSPTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT
Sbjct: 481 PSPTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT 520
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 1057 bits (2733), Expect = 0.0
Identities = 518/520 (99%), Positives = 518/520 (99%), Gaps = 2/520 (0%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG 180
YKRENPGMFSWEIRDRLLKDGHCDRSTVPS VSSISRVLRIKFGKKEEEDEADKKEDDG
Sbjct: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPS--VSSISRVLRIKFGKKEEEDEADKKEDDG 178
Query: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH
Sbjct: 179 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 238
Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL
Sbjct: 239 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 298
Query: 301 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 360
PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS
Sbjct: 299 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 358
Query: 361 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 420
YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS
Sbjct: 359 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 418
Query: 421 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSECLVPWASPVPI 480
ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSECLVPWASPVPI
Sbjct: 419 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSECLVPWASPVPI 478
Query: 481 PSPTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT 520
PSPTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT
Sbjct: 479 PSPTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT 518
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 957 bits (2475), Expect = 0.0
Identities = 467/468 (99%), Positives = 468/468 (100%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG 180
YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG
Sbjct: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG 180
Query: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH
Sbjct: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL
Sbjct: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
Query: 301 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 360
PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS
Sbjct: 301 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 360
Query: 361 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 420
YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS
Sbjct: 361 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 420
Query: 421 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQS 468
ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQ+
Sbjct: 421 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQT 468
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 742 bits (1915), Expect = 0.0
Identities = 374/486 (76%), Positives = 413/486 (84%), Gaps = 21/486 (4%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
YKRENPGMFSWEIRD+LLKD CDR+TVPS VSSISR+LR KFGK EEE EAD K+
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177
Query: 178 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA 235
++ EKKAKHSIDGIL ++ + + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+A
Sbjct: 178 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA 237
Query: 236 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT 295
FERTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT
Sbjct: 238 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT 297
Query: 296 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY 352
MPTLP YQL +++Y T+I Q D STVHRPQPLPPST+HQ + + D+SSAY
Sbjct: 298 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAY 354
Query: 353 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISP 408
RH FSSY+DSF+ P+ PSN MNP + NGLSPQVM +L N VP QPQ D+++SP
Sbjct: 355 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP 414
Query: 409 LHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQS 468
L GGL+ T++SASCSQR D +K DSLPTSQ+YCPPTYSTTGYS+DPV GYQYGQYGQS
Sbjct: 415 LTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS 474
Query: 469 ECLVPW 474
+ PW
Sbjct: 475 K---PW 477
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 740 bits (1910), Expect = 0.0
Identities = 372/480 (77%), Positives = 410/480 (85%), Gaps = 18/480 (3%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
YKRENPGMFSWEIRD+LLKD CDR+TVPS VSSISR+LR KFGK EEE EAD K+
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177
Query: 178 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA 235
++ EKKAKHSIDGIL ++ + + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+A
Sbjct: 178 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA 237
Query: 236 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT 295
FERTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT
Sbjct: 238 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT 297
Query: 296 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY 352
MPTLP YQL +++Y T+I Q D STVHRPQPLPPST+HQ + + D+SSAY
Sbjct: 298 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAY 354
Query: 353 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISP 408
RH FSSY+DSF+ P+ PSN MNP + NGLSPQVM +L N VP QPQ D+++SP
Sbjct: 355 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP 414
Query: 409 LHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQS 468
L GGL+ T++SASCSQR D +K DSLPTSQ+YCPPTYSTTGYS+DPV GYQYGQYGQS
Sbjct: 415 LTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS 474
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 740 bits (1910), Expect = 0.0
Identities = 372/480 (77%), Positives = 410/480 (85%), Gaps = 18/480 (3%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
YKRENPGMFSWEIRD+LLKD CDR+TVPS VSSISR+LR KFGK EEE EAD K+
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177
Query: 178 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA 235
++ EKKAKHSIDGIL ++ + + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+A
Sbjct: 178 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA 237
Query: 236 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT 295
FERTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT
Sbjct: 238 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT 297
Query: 296 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY 352
MPTLP YQL +++Y T+I Q D STVHRPQPLPPST+HQ + + D+SSAY
Sbjct: 298 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAY 354
Query: 353 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISP 408
RH FSSY+DSF+ P+ PSN MNP + NGLSPQVM +L N VP QPQ D+++SP
Sbjct: 355 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP 414
Query: 409 LHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQS 468
L GGL+ T++SASCSQR D +K DSLPTSQ+YCPPTYSTTGYS+DPV GYQYGQYGQS
Sbjct: 415 LTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS 474
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 733 bits (1893), Expect = 0.0
Identities = 371/480 (77%), Positives = 409/480 (85%), Gaps = 19/480 (3%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+ V TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPK-VTTPDVEKKIEE 119
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
YKRENPGMFSWEIRD+LLKD CDR+TVPS VSSISR+LR KFGK EEE EAD K+
Sbjct: 120 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 176
Query: 178 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA 235
++ EKKAKHSIDGIL ++ + + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+A
Sbjct: 177 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA 236
Query: 236 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT 295
FERTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT
Sbjct: 237 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT 296
Query: 296 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY 352
MPTLP YQL +++Y T+I Q D STVHRPQPLPPST+HQ + + D+SSAY
Sbjct: 297 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAY 353
Query: 353 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISP 408
RH FSSY+DSF+ P+ PSN MNP + NGLSPQVM +L N VP QPQ D+++SP
Sbjct: 354 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP 413
Query: 409 LHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQS 468
L GGL+ T++SASCSQR D +K DSLPTSQ+YCPPTYSTTGYS+DPV GYQYGQYGQS
Sbjct: 414 LTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS 473
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 620 bits (1598), Expect = e-177
Identities = 316/404 (78%), Positives = 346/404 (85%), Gaps = 18/404 (4%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
YKRENPGMFSWEIRD+LLKD CDR+TVPS VSSISR+LR KFGK EEE EAD K+
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177
Query: 178 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA 235
++ EKKAKHSIDGIL ++ + + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+A
Sbjct: 178 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA 237
Query: 236 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT 295
FERTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT
Sbjct: 238 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT 297
Query: 296 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY 352
MPTLP YQL +++Y T+I Q D STVHRPQPLPPST+HQ + + D+SSAY
Sbjct: 298 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAY 354
Query: 353 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGN 392
RH FSSY+DSF+ P+ PSN MNP + NGLSPQV I+ +
Sbjct: 355 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVPFIISS 398
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 620 bits (1598), Expect = e-177
Identities = 316/404 (78%), Positives = 346/404 (85%), Gaps = 18/404 (4%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
YKRENPGMFSWEIRD+LLKD CDR+TVPS VSSISR+LR KFGK EEE EAD K+
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177
Query: 178 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA 235
++ EKKAKHSIDGIL ++ + + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+A
Sbjct: 178 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA 237
Query: 236 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT 295
FERTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT
Sbjct: 238 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT 297
Query: 296 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY 352
MPTLP YQL +++Y T+I Q D STVHRPQPLPPST+HQ + + D+SSAY
Sbjct: 298 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAY 354
Query: 353 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGN 392
RH FSSY+DSF+ P+ PSN MNP + NGLSPQV I+ +
Sbjct: 355 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVPFIISS 398
>gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]
Length = 206
Score = 343 bits (881), Expect = 2e-94
Identities = 172/205 (83%), Positives = 182/205 (88%), Gaps = 6/205 (2%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
YKRENPGMFSWEIRD+LLKD CDR+TVPS VSSISR+LR KFGK EEE EAD K+
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177
Query: 178 DDGEKKAKHSIDGILGDKGNRLDEG 202
++ EKKAKHSIDGIL ++G L G
Sbjct: 178 EESEKKAKHSIDGILSERGKALVSG 202
>gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]
Length = 215
Score = 343 bits (880), Expect = 2e-94
Identities = 171/201 (85%), Positives = 181/201 (90%), Gaps = 6/201 (2%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
YKRENPGMFSWEIRD+LLKD CDR+TVPS VSSISR+LR KFGK EEE EAD K+
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177
Query: 178 DDGEKKAKHSIDGILGDKGNR 198
++ EKKAKHSIDGIL ++G R
Sbjct: 178 EESEKKAKHSIDGILSERGKR 198
>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 257 bits (656), Expect = 2e-68
Identities = 179/451 (39%), Positives = 230/451 (50%), Gaps = 83/451 (18%)
Query: 38 VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97
VNQLGGVF+NGRPLP+ R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 8 VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
Query: 98 PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSIS 157
P AIGGSKPR VATP+V KI +YKRE P +F+WEIRDRLL +G C +PS VSSI+
Sbjct: 68 PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPS--VSSIN 124
Query: 158 RVLRIKFGKKEE-------------------------------------EDEADKKEDDG 180
RVLR +K++ +D ++E G
Sbjct: 125 RVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGG 184
Query: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
E S +G E SD E++ L LKRK +R+RT+FT EQ+E LEK FERTH
Sbjct: 185 ENTNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTH 233
Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
YPD++ RE LA + L EAR+QVWFSNRRA+WR++ P P + +
Sbjct: 234 YPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFST 293
Query: 301 PPYQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFS 359
YQ +P T P ++ + GS + R A +T SA SF+
Sbjct: 294 SVYQPIPQPTTPVSSFT--SGSMLGRTD---------------TALTNTYSALPPMPSFT 336
Query: 360 SYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQADFSISPLHGGLDSAT 417
++ M P PS + + + P S+ G + PP Q + P+ G T
Sbjct: 337 MANNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPM--GTSGTT 392
Query: 418 SISASCSQRADSIKPGDSLPTSQAYCPPTYS 448
S I PG S+P P S
Sbjct: 393 STGL--------ISPGVSVPVQVPGSEPDMS 415
>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 257 bits (656), Expect = 2e-68
Identities = 179/451 (39%), Positives = 230/451 (50%), Gaps = 83/451 (18%)
Query: 38 VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97
VNQLGGVF+NGRPLP+ R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 8 VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
Query: 98 PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSIS 157
P AIGGSKPR VATP+V KI +YKRE P +F+WEIRDRLL +G C +PS VSSI+
Sbjct: 68 PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPS--VSSIN 124
Query: 158 RVLRIKFGKKEE-------------------------------------EDEADKKEDDG 180
RVLR +K++ +D ++E G
Sbjct: 125 RVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGG 184
Query: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
E S +G E SD E++ L LKRK +R+RT+FT EQ+E LEK FERTH
Sbjct: 185 ENTNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTH 233
Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
YPD++ RE LA + L EAR+QVWFSNRRA+WR++ P P + +
Sbjct: 234 YPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFST 293
Query: 301 PPYQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFS 359
YQ +P T P ++ + GS + R A +T SA SF+
Sbjct: 294 SVYQPIPQPTTPVSSFT--SGSMLGRTD---------------TALTNTYSALPPMPSFT 336
Query: 360 SYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQADFSISPLHGGLDSAT 417
++ M P PS + + + P S+ G + PP Q + P+ G T
Sbjct: 337 MANNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPM--GTSGTT 392
Query: 418 SISASCSQRADSIKPGDSLPTSQAYCPPTYS 448
S I PG S+P P S
Sbjct: 393 STGL--------ISPGVSVPVQVPGSEPDMS 415
>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
Length = 436
Score = 247 bits (631), Expect = 2e-65
Identities = 179/465 (38%), Positives = 230/465 (49%), Gaps = 97/465 (20%)
Query: 38 VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83
VNQLGGVF+NGRPLP+ R KIVE+AH G RPC ISR L+ VS+GCV
Sbjct: 8 VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
Query: 84 SKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHC 143
SKIL RY ETGSIRP AIGGSKPR VATP+V KI +YKRE P +F+WEIRDRLL +G C
Sbjct: 68 SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126
Query: 144 DRSTVPSGLVSSISRVLRIKFGKKEE---------------------------------- 169
+PS VSSI+RVLR +K++
Sbjct: 127 TNDNIPS--VSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPG 184
Query: 170 ---EDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTA 226
+D ++E GE S +G E SD E++ L LKRK +R+RT+FT
Sbjct: 185 QPTQDGCQQQEGGGENTNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQ 233
Query: 227 EQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNH 286
EQ+E LEK FERTHYPD++ RE LA + L EAR+QVWFSNRRA+WR++
Sbjct: 234 EQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQAS 293
Query: 287 LLPGGFPPTGMPTLPPYQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAA 345
P P + + YQ +P T P ++ + GS + R A
Sbjct: 294 NTPSHIPISSSFSTSVYQPIPQPTTPVSSFT--SGSMLGRTD---------------TAL 336
Query: 346 ADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQAD 403
+T SA SF+ ++ M P PS + + + P S+ G + PP Q
Sbjct: 337 TNTYSALPPMPSFTMANNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTH 394
Query: 404 FSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYS 448
+ P+ G TS I PG S+P P S
Sbjct: 395 MNSQPM--GTSGTTSTGL--------ISPGVSVPVQVPGSEPDMS 429
>gi|9951920 paired box 5 [Homo sapiens]
Length = 391
Score = 219 bits (557), Expect = 6e-57
Identities = 148/371 (39%), Positives = 192/371 (51%), Gaps = 43/371 (11%)
Query: 25 FPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVS 84
+P ++ G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVS
Sbjct: 7 YPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVS 66
Query: 85 KILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCD 144
KIL RY ETGSI+PG IGGSKP+ VATP V +KI EYKR+NP MF+WEIRDRLL + CD
Sbjct: 67 KILGRYYETGSIKPGVIGGSKPK-VATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCD 125
Query: 145 RSTVPSGLVSSISRVLRIKFGKKEEEDEADKKE--------------DDGEKKAKHSIDG 190
TVPS VSSI+R++R K + + + +SI G
Sbjct: 126 NDTVPS--VSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISG 183
Query: 191 ILG-------DKGNRLDEG---SDVESEPDLP---LKRKQRRSRTTFTAEQLEELEKAFE 237
ILG + DEG S V + LP RKQ R FT +QLE L++ FE
Sbjct: 184 ILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRG-DLFTQQQLEVLDRVFE 242
Query: 238 RTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGM 297
R HY DI+T E + + TE + + + A +PG P
Sbjct: 243 RQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPG---PQSY 299
Query: 298 PTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHS 357
P + L +T P G H P P + L ++ S + +
Sbjct: 300 PIVTGRDLASTTLP--------GYPPHVP-PAGQGSYSAPTLTGMVPGSEFSGSPYSHPQ 350
Query: 358 FSSYSDSFMNP 368
+SSY+DS+ P
Sbjct: 351 YSSYNDSWRFP 361
>gi|34878716 paired box protein 2 isoform d [Homo sapiens]
Length = 408
Score = 213 bits (543), Expect = 3e-55
Identities = 140/342 (40%), Positives = 183/342 (53%), Gaps = 52/342 (15%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
Query: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG 193
SSI+R++R K + + +SI+GILG
Sbjct: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
Query: 194 ---DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 242
G + DV +S+ + RK R+ TFT +QLE L++ FER YP
Sbjct: 193 IPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYP 251
Query: 243 DIYTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FP 293
D++ E + + E + S+ A + G+N + + G
Sbjct: 252 DVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMA 311
Query: 294 PTGMPTLPPYQLP--DSTYPTTTI------SQDGGSTVHRPQ 327
T +P PP+ P +YPT+T+ S+ G+ PQ
Sbjct: 312 STTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQ 353
>gi|34878701 paired box protein 2 isoform b [Homo sapiens]
Length = 393
Score = 213 bits (543), Expect = 3e-55
Identities = 140/342 (40%), Positives = 183/342 (53%), Gaps = 52/342 (15%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
Query: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG 193
SSI+R++R K + + +SI+GILG
Sbjct: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
Query: 194 ---DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 242
G + DV +S+ + RK R+ TFT +QLE L++ FER YP
Sbjct: 193 IPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYP 251
Query: 243 DIYTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FP 293
D++ E + + E + S+ A + G+N + + G
Sbjct: 252 DVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMA 311
Query: 294 PTGMPTLPPYQLP--DSTYPTTTI------SQDGGSTVHRPQ 327
T +P PP+ P +YPT+T+ S+ G+ PQ
Sbjct: 312 STTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQ 353
>gi|34878709 paired box protein 2 isoform c [Homo sapiens]
Length = 396
Score = 213 bits (542), Expect = 3e-55
Identities = 136/325 (41%), Positives = 178/325 (54%), Gaps = 46/325 (14%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
Query: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG 193
SSI+R++R K + + +SI+GILG
Sbjct: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
Query: 194 ---DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 242
G + DV +S+ + RK R+ TFT +QLE L++ FER YP
Sbjct: 193 IPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYP 251
Query: 243 DIYTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FP 293
D++ E + + E + S+ A + G+N + + G
Sbjct: 252 DVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMA 311
Query: 294 PTGMPTLPPYQLP--DSTYPTTTIS 316
T +P PP+ P +YPT+T++
Sbjct: 312 STTLPGYPPHVPPTGQGSYPTSTLA 336
>gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]
Length = 387
Score = 206 bits (524), Expect = 4e-53
Identities = 158/410 (38%), Positives = 199/410 (48%), Gaps = 86/410 (20%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPS--V 125
Query: 154 SSISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGI 191
SSI+R++R K F + A K G + +SI+G+
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGL 185
Query: 192 LG------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
LG DK D D ++S+ RK R+ F+ LE LE FER H
Sbjct: 186 LGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQH 244
Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
YP+ Y + + + G L N L G TL
Sbjct: 245 YPEAYASP---------------------SHTKGEQGLYPLPLLNSTL-----DDGKATL 278
Query: 301 PPYQLP-------DSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA------D 347
P P TYP + G T+ P P T QG A++A A
Sbjct: 279 TPSNTPLGRNLSTHQTYPVVAGREMVGPTLPGYPPHIP-TSGQGSYASSAIAGMVAGSEY 337
Query: 348 TSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVP 397
+ +AYG +SSYS+++ P + S SP S PSA P
Sbjct: 338 SGNAYG-HTPYSSYSEAWRFPNS--------SLLSSPYYYSSTSRPSAPP 378
>gi|34878699 paired box protein 2 isoform a [Homo sapiens]
Length = 416
Score = 204 bits (519), Expect = 2e-52
Identities = 142/365 (38%), Positives = 187/365 (51%), Gaps = 75/365 (20%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
Query: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGIL- 192
SSI+R++R K + + +SI+GIL
Sbjct: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
Query: 193 -----GDKGNR--------------------------LDEGS--DVESEPDLPLKRKQRR 219
G+K R + EGS + +S+ + RK R
Sbjct: 193 IPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLR 252
Query: 220 SRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF-------SNRRARW 272
+ TFT +QLE L++ FER YPD++ E + + E + S+ A
Sbjct: 253 A-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSAST 311
Query: 273 RKQAGANQLAAFNHLLPGG--FPPTGMPTLPPYQLP--DSTYPTTTI------SQDGGST 322
+ G+N + + G T +P PP+ P +YPT+T+ S+ G+
Sbjct: 312 NPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNP 371
Query: 323 VHRPQ 327
PQ
Sbjct: 372 YSHPQ 376
>gi|34878703 paired box protein 2 isoform e [Homo sapiens]
Length = 431
Score = 204 bits (519), Expect = 2e-52
Identities = 142/365 (38%), Positives = 187/365 (51%), Gaps = 75/365 (20%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132
Query: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGIL- 192
SSI+R++R K + + +SI+GIL
Sbjct: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192
Query: 193 -----GDKGNR--------------------------LDEGS--DVESEPDLPLKRKQRR 219
G+K R + EGS + +S+ + RK R
Sbjct: 193 IPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLR 252
Query: 220 SRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF-------SNRRARW 272
+ TFT +QLE L++ FER YPD++ E + + E + S+ A
Sbjct: 253 A-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSAST 311
Query: 273 RKQAGANQLAAFNHLLPGG--FPPTGMPTLPPYQLP--DSTYPTTTI------SQDGGST 322
+ G+N + + G T +P PP+ P +YPT+T+ S+ G+
Sbjct: 312 NPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNP 371
Query: 323 VHRPQ 327
PQ
Sbjct: 372 YSHPQ 376
>gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]
Length = 398
Score = 201 bits (512), Expect = 1e-51
Identities = 155/415 (37%), Positives = 196/415 (47%), Gaps = 86/415 (20%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPS--V 125
Query: 154 SSISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGI 191
SSI+R++R K F + A K G + +SI+G+
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGL 185
Query: 192 LG------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
LG DK D D ++S+ RK R+ F+ LE LE FER H
Sbjct: 186 LGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQH 244
Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
YP+ Y + + + G L N L G TL
Sbjct: 245 YPEAYASP---------------------SHTKGEQGLYPLPLLNSTL-----DDGKATL 278
Query: 301 PPYQLP-------DSTYPTTTI-------SQDGGSTVHRPQP-LPPSTMHQGGLAAAAAA 345
P P TYP GS P P LPP T G + A +
Sbjct: 279 TPSNTPLGRNLSTHQTYPVVAAPPFWICSKSAPGSRPSMPFPMLPPCT----GSSRARPS 334
Query: 346 ADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQP 400
+ +G R + + +P A M P+ + Q ++ L P A PP P
Sbjct: 335 SQGERWWGPRCPDTHPT----SPPADRAAMPPLPSQAWWQEVNTLAMPMATPPTP 385
>gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]
Length = 321
Score = 200 bits (509), Expect = 2e-51
Identities = 120/245 (48%), Positives = 147/245 (60%), Gaps = 37/245 (15%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPS--V 125
Query: 154 SSISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGI 191
SSI+R++R K F + A K G + +SI+G+
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGL 185
Query: 192 LG------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
LG DK D D ++S+ RK R+ F+ LE LE FER H
Sbjct: 186 LGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQH 244
Query: 241 YPDIY 245
YP+ Y
Sbjct: 245 YPEAY 249
>gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]
Length = 287
Score = 200 bits (509), Expect = 2e-51
Identities = 120/245 (48%), Positives = 147/245 (60%), Gaps = 37/245 (15%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPS--V 125
Query: 154 SSISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGI 191
SSI+R++R K F + A K G + +SI+G+
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGL 185
Query: 192 LG------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
LG DK D D ++S+ RK R+ F+ LE LE FER H
Sbjct: 186 LGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQH 244
Query: 241 YPDIY 245
YP+ Y
Sbjct: 245 YPEAY 249
>gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]
Length = 450
Score = 200 bits (509), Expect = 2e-51
Identities = 120/245 (48%), Positives = 147/245 (60%), Gaps = 37/245 (15%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPS--V 125
Query: 154 SSISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGI 191
SSI+R++R K F + A K G + +SI+G+
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGL 185
Query: 192 LG------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
LG DK D D ++S+ RK R+ F+ LE LE FER H
Sbjct: 186 LGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQH 244
Query: 241 YPDIY 245
YP+ Y
Sbjct: 245 YPEAY 249
>gi|197276661 paired box 1 [Homo sapiens]
Length = 534
Score = 188 bits (477), Expect = 1e-47
Identities = 103/162 (63%), Positives = 120/162 (74%), Gaps = 9/162 (5%)
Query: 8 VPRMMRPAPGQNYPRTGFPLEVSTPLGQ----GRVNQLGGVFINGRPLPNHIRHKIVEMA 63
+P P+PG +P +++ PL G VNQLGGVF+NGRPLPN IR +IVE+A
Sbjct: 70 LPDCAGPSPG--HPGHPGARQLAGPLAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELA 127
Query: 64 HHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKR 123
GIRPC ISRQLRVSHGCVSKIL RY ETGSI PGAIGGSKPR V TP+V K I +YK+
Sbjct: 128 QLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPR-VTTPNVVKHIRDYKQ 186
Query: 124 ENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFG 165
+PG+F+WEIRDRLL DG CD+ VPS VSSISR+LR K G
Sbjct: 187 GDPGIFAWEIRDRLLADGVCDKYNVPS--VSSISRILRNKIG 226
>gi|7242167 paired box 9 [Homo sapiens]
Length = 341
Score = 186 bits (473), Expect = 3e-47
Identities = 97/139 (69%), Positives = 108/139 (77%), Gaps = 3/139 (2%)
Query: 36 GRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGS 95
G VNQLGGVF+NGRPLPN IR +IVE+A GIRPC ISRQLRVSHGCVSKIL RY ETGS
Sbjct: 6 GEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGS 65
Query: 96 IRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSS 155
I PGAIGGSKPR V TP V K I YK+ +PG+F+WEIRDRLL DG CD+ VPS VSS
Sbjct: 66 ILPGAIGGSKPR-VTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPS--VSS 122
Query: 156 ISRVLRIKFGKKEEEDEAD 174
ISR+LR K G ++ D
Sbjct: 123 ISRILRNKIGNLAQQGHYD 141
>gi|170784824 paired box 4 [Homo sapiens]
Length = 343
Score = 186 bits (472), Expect = 4e-47
Identities = 128/327 (39%), Positives = 167/327 (51%), Gaps = 45/327 (13%)
Query: 38 VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97
+NQLGG+F+NGRPLP R +IV +A G+RPC ISR L+VS+GCVSKIL RY TG +
Sbjct: 1 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE 60
Query: 98 PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSIS 157
P IGGSKPR +ATP V +I + K E P +F+WEI+ +L +G C + PS VSSI+
Sbjct: 61 PKGIGGSKPR-LATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPS--VSSIN 117
Query: 158 RVLRIKFGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQ 217
RVLR +ED G + +L GS+ P
Sbjct: 118 RVLRA------------LQEDQGLPCTRLRSPAVLAPAVLTPHSGSET---PRGTHPGTG 162
Query: 218 RRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ-- 275
R+RT F+ Q E LEK F+R YPD R +LA T L E V+VWFSNRRA+WR+Q
Sbjct: 163 HRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEK 222
Query: 276 -------AGANQLAAFNHLL---------PGGFPPTGMPTLPP-----YQLPDSTYPTTT 314
GA+Q + PG P +P L P YQL +T P
Sbjct: 223 LKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERC 282
Query: 315 ISQDGGSTVHRP----QPLPPSTMHQG 337
+S +P P P+++ G
Sbjct: 283 LSDTPPKACLKPCWGHLPPQPNSLDSG 309
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 114 bits (285), Expect = 2e-25
Identities = 76/158 (48%), Positives = 91/158 (57%), Gaps = 22/158 (13%)
Query: 189 DGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTRE 248
+G G+ L GSD SE L LKRKQRR RTTFT+ QLEELE+AF++THYPD++TRE
Sbjct: 303 EGKDGEDSVCLSAGSD--SEEGL-LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTRE 359
Query: 249 ELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDS 308
ELA R LTEARVQVWF NRRA+WRK+ A A H P G+P P +
Sbjct: 360 ELAMRLDLTEARVQVWFQNRRAKWRKREKA---GAQTH-------PPGLPFPGPL---SA 406
Query: 309 TYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA 346
T+P + H P + AAAAAAA
Sbjct: 407 THPLSPYLDASPFPPHHP------ALDSAWTAAAAAAA 438
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 112 bits (280), Expect = 8e-25
Identities = 68/192 (35%), Positives = 101/192 (52%), Gaps = 13/192 (6%)
Query: 214 KRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWR 273
K K+RR+RTTF+ QLEELEK F++THYPD+Y RE+LA RT LTEARVQVWF NRRA+WR
Sbjct: 150 KSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWR 209
Query: 274 KQAGANQLAAFNHLLPGGFPPTGMPTLPPY-QLPDSTYPTTTISQDGGSTVHRPQPLP-- 330
K+ ++ + + + +P + QL +S + + GG + P+ +P
Sbjct: 210 KRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPGSGSPGGPCLVSPEGIPSP 269
Query: 331 ---PSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNG--LSPQ 385
P + G +A S+A+ +S + P + P S+G SP
Sbjct: 270 CMSPYSHPHGSVAGFMGVPAPSAAHPGIYSIHGFP-----PTLGGHSFEPSSDGDYKSPS 324
Query: 386 VMSILGNPSAVP 397
++S+ P P
Sbjct: 325 LVSLRVKPKEPP 336
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,271,637
Number of Sequences: 37866
Number of extensions: 1360609
Number of successful extensions: 6755
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 325
Number of HSP's successfully gapped in prelim test: 277
Number of HSP's that attempted gapping in prelim test: 5810
Number of HSP's gapped (non-prelim): 1090
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.