Guide to the Human Genome
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Search of human proteins with 4505581

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505581 protein kinase, interferon-inducible double stranded
RNA dependent activator isoform 1 [Homo sapiens]
         (313 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505581 protein kinase, interferon-inducible double stranded ...   635   0.0  
gi|213417911 protein kinase, interferon-inducible double strande...   593   e-170
gi|213417919 protein kinase, interferon-inducible double strande...   585   e-167
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]        260   1e-69
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]        258   6e-69
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]        258   6e-69
gi|7657625 staufen homolog 2 [Homo sapiens]                            79   7e-15
gi|82659089 staufen isoform a [Homo sapiens]                           74   2e-13
gi|82659087 staufen isoform b [Homo sapiens]                           74   2e-13
gi|82659085 staufen isoform a [Homo sapiens]                           74   2e-13
gi|82659083 staufen isoform a [Homo sapiens]                           74   2e-13
gi|82659091 staufen isoform c [Homo sapiens]                           69   5e-12
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa...    55   6e-08
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa...    52   5e-07
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa...    52   5e-07
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa...    51   2e-06
gi|38488720 DiGeorge syndrome critical region gene 8 [Homo sapiens]    42   5e-04
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo...    38   0.013
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s...    38   0.013
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s...    38   0.013
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s...    38   0.013
gi|208431829 eukaryotic translation initiation factor 2-alpha ki...    37   0.017
gi|208431827 eukaryotic translation initiation factor 2-alpha ki...    37   0.017
gi|4506103 eukaryotic translation initiation factor 2-alpha kina...    37   0.017
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]        36   0.039
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom...    35   0.066
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom...    35   0.066
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom...    35   0.066
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho...    34   0.15 
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho...    34   0.15 

>gi|4505581 protein kinase, interferon-inducible double stranded RNA
           dependent activator isoform 1 [Homo sapiens]
          Length = 313

 Score =  635 bits (1637), Expect = 0.0
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 1   MSQSRHRAEAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQ 60
           MSQSRHRAEAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQ
Sbjct: 1   MSQSRHRAEAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQ 60

Query: 61  IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQ 120
           IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQ
Sbjct: 61  IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQ 120

Query: 121 PKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQA 180
           PKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQA
Sbjct: 121 PKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQA 180

Query: 181 KRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTD 240
           KRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTD
Sbjct: 181 KRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTD 240

Query: 241 YIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAH 300
           YIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAH
Sbjct: 241 YIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAH 300

Query: 301 NALQYLKIIAERK 313
           NALQYLKIIAERK
Sbjct: 301 NALQYLKIIAERK 313


>gi|213417911 protein kinase, interferon-inducible double stranded
           RNA dependent activator isoform 2 [Homo sapiens]
          Length = 302

 Score =  593 bits (1530), Expect = e-170
 Identities = 293/295 (99%), Positives = 293/295 (99%)

Query: 19  GTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCT 78
           G  SLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCT
Sbjct: 8   GFCSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCT 67

Query: 79  GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHH 138
           GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHH
Sbjct: 68  GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHH 127

Query: 139 GWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPE 198
           GWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPE
Sbjct: 128 GWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPE 187

Query: 199 NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKEQGFNITY 258
           NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKEQGFNITY
Sbjct: 188 NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKEQGFNITY 247

Query: 259 LDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK 313
           LDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK
Sbjct: 248 LDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK 302


>gi|213417919 protein kinase, interferon-inducible double stranded
           RNA dependent activator isoform 3 [Homo sapiens]
          Length = 288

 Score =  585 bits (1509), Expect = e-167
 Identities = 288/288 (100%), Positives = 288/288 (100%)

Query: 26  MITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKK 85
           MITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKK
Sbjct: 1   MITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKK 60

Query: 86  LAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEY 145
           LAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEY
Sbjct: 61  LAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEY 120

Query: 146 TLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTN 205
           TLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTN
Sbjct: 121 TLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTN 180

Query: 206 VVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKEQGFNITYLDIDELS 265
           VVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKEQGFNITYLDIDELS
Sbjct: 181 VVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKEQGFNITYLDIDELS 240

Query: 266 ANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK 313
           ANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK
Sbjct: 241 ANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK 288


>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
          Length = 366

 Score =  260 bits (665), Expect = 1e-69
 Identities = 152/363 (41%), Positives = 203/363 (55%), Gaps = 63/363 (17%)

Query: 14  EREDSGTF------SLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFT 67
           E + SGT       S+ +M+ A PGKTPI +L EYG +    PVY+  +++ Q H P FT
Sbjct: 4   EEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFT 63

Query: 68  FRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANA--------SICFAVPDPLMPD--- 116
           FRVTVGD +CTG+G SKK AKH+AAE A+  LK  +        S  F+  D  +P+   
Sbjct: 64  FRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIP 123

Query: 117 --------------------------PSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQE 150
                                     P    +++ NP+G+LQEL +  GWRLPEYT++QE
Sbjct: 124 VFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQE 183

Query: 151 GGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNI-----------SPEN 199
            GPAH++E+T  CR+E F+E G G SKK AKRNAA K L +   +             ++
Sbjct: 184 SGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDD 243

Query: 200 HIS------LTNVVGHSLGCTWHSLRNSPGEKINLLKR---SLLSIPNTDYIQLLSEIAK 250
           H S      L  +     GCTW SLRNS GEKI  L+      L        ++LSE+++
Sbjct: 244 HFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSE 303

Query: 251 EQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIA 310
           EQ F+++YLDI+ELS +G  QCL ELST P TVCHGS  +   A+ +AA  ALQYLKI+A
Sbjct: 304 EQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMA 363

Query: 311 ERK 313
             K
Sbjct: 364 GSK 366


>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
          Length = 345

 Score =  258 bits (658), Expect = 6e-69
 Identities = 147/345 (42%), Positives = 195/345 (56%), Gaps = 57/345 (16%)

Query: 26  MITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKK 85
           M+ A PGKTPI +L EYG +    PVY+  +++ Q H P FTFRVTVGD +CTG+G SKK
Sbjct: 1   MLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKK 60

Query: 86  LAKHRAAEAAINILKANA--------SICFAVPDPLMPD--------------------- 116
            AKH+AAE A+  LK  +        S  F+  D  +P+                     
Sbjct: 61  AAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTR 120

Query: 117 --------PSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESF 168
                   P    +++ NP+G+LQEL +  GWRLPEYT++QE GPAH++E+T  CR+E F
Sbjct: 121 SPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERF 180

Query: 169 METGKGASKKQAKRNAAEKFLAKFSNI-----------SPENHIS------LTNVVGHSL 211
           +E G G SKK AKRNAA K L +   +             ++H S      L  +     
Sbjct: 181 IEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGP 240

Query: 212 GCTWHSLRNSPGEKINLLKR---SLLSIPNTDYIQLLSEIAKEQGFNITYLDIDELSANG 268
           GCTW SLRNS GEKI  L+      L        ++LSE+++EQ F+++YLDI+ELS +G
Sbjct: 241 GCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSG 300

Query: 269 QYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK 313
             QCL ELST P TVCHGS  +   A+ +AA  ALQYLKI+A  K
Sbjct: 301 LCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK 345


>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
          Length = 345

 Score =  258 bits (658), Expect = 6e-69
 Identities = 147/345 (42%), Positives = 195/345 (56%), Gaps = 57/345 (16%)

Query: 26  MITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKK 85
           M+ A PGKTPI +L EYG +    PVY+  +++ Q H P FTFRVTVGD +CTG+G SKK
Sbjct: 1   MLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKK 60

Query: 86  LAKHRAAEAAINILKANA--------SICFAVPDPLMPD--------------------- 116
            AKH+AAE A+  LK  +        S  F+  D  +P+                     
Sbjct: 61  AAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTR 120

Query: 117 --------PSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESF 168
                   P    +++ NP+G+LQEL +  GWRLPEYT++QE GPAH++E+T  CR+E F
Sbjct: 121 SPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERF 180

Query: 169 METGKGASKKQAKRNAAEKFLAKFSNI-----------SPENHIS------LTNVVGHSL 211
           +E G G SKK AKRNAA K L +   +             ++H S      L  +     
Sbjct: 181 IEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGP 240

Query: 212 GCTWHSLRNSPGEKINLLKR---SLLSIPNTDYIQLLSEIAKEQGFNITYLDIDELSANG 268
           GCTW SLRNS GEKI  L+      L        ++LSE+++EQ F+++YLDI+ELS +G
Sbjct: 241 GCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSG 300

Query: 269 QYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK 313
             QCL ELST P TVCHGS  +   A+ +AA  ALQYLKI+A  K
Sbjct: 301 LCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK 345


>gi|7657625 staufen homolog 2 [Homo sapiens]
          Length = 479

 Score = 78.6 bits (192), Expect = 7e-15
 Identities = 71/268 (26%), Positives = 121/268 (45%), Gaps = 26/268 (9%)

Query: 33  KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 91
           K+ I ++ E  +K +N+PV +E  +     H+ +F  RV+VG+ +  GEG SKKL+K RA
Sbjct: 174 KSEISLVFEIALK-RNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRA 232

Query: 92  AEAAINILKANASICFAVPDPLMPDP----SKQPK----------NQLNPIGSLQELAIH 137
           A   +  LK         P P++  P     K+PK            +NPI  L ++   
Sbjct: 233 ATTVLQELKK------LPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQA 286

Query: 138 HGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISP 197
              + P+Y L  E G   +RE+    ++ + + TG G +KK AK+NAAE  L +    + 
Sbjct: 287 KKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKAS 346

Query: 198 ENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKE-QGFNI 256
            N        G + G  W   +    E  N   + +L +    Y ++ +   K   G  +
Sbjct: 347 TNLQDQLEKTGENKG--WSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTL 404

Query: 257 TYLDIDELS-ANGQYQCLAELSTSPITV 283
            YL   +++  +  +  ++  S S  T+
Sbjct: 405 GYLSPKDMNQPSSSFFSISPTSNSSATI 432



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 26/145 (17%)

Query: 66  FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKN-- 123
           F  ++TVG+    GEG +++ A+H AA  A+  L+              P P + P+N  
Sbjct: 114 FYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNE------------PIPERSPQNGE 161

Query: 124 -----------QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETG 172
                        + I  + E+A+     +  + + +E GP H + + T   +  F   G
Sbjct: 162 SGKDMDDDKDANKSEISLVFEIALKRNMPV-SFEVIKESGPPHMKSFVTRVSVGEFSAEG 220

Query: 173 KGASKKQAKRNAAEKFLAKFSNISP 197
           +G SKK +K+ AA   L +   + P
Sbjct: 221 EGNSKKLSKKRAATTVLQELKKLPP 245


>gi|82659089 staufen isoform a [Homo sapiens]
          Length = 496

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 12/168 (7%)

Query: 33  KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 91
           K+ I  + E  +K +N+PV +E  R     H+  F  +V+VG+    GEG SKK++K  A
Sbjct: 102 KSEISQVFEIALK-RNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNA 160

Query: 92  AEAAINILK----------ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWR 141
           A A +  LK              I       + P  S +    +NPI  L ++      +
Sbjct: 161 AIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEK 220

Query: 142 LPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFL 189
            PEYTL  E G   +RE+    ++ +    G G +KK AKRNAAE  L
Sbjct: 221 EPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 268



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 50/180 (27%), Positives = 81/180 (45%), Gaps = 14/180 (7%)

Query: 23  LGKMITAKPGK--TPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRV--TVGDITCT 78
           LGK    KP    + +Q  + Y M+    P     R      VP   ++V  +VG     
Sbjct: 3   LGKKPMYKPVDPYSRMQSTYNYNMRGGAYP----PRYFYPFPVPPLLYQVELSVGGQQFN 58

Query: 79  GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHH 138
           G+G +++ AKH AA  A+ IL+        +P+ L  +  +  +  LN     Q   I  
Sbjct: 59  GKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRESEEENLNKSEISQVFEIAL 113

Query: 139 GWRLP-EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISP 197
              LP  + +++E GP H + + T   +  F+  G+G SKK +K+NAA   L +   + P
Sbjct: 114 KRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPP 173



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)

Query: 66  FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 123
           F  +V VG+ T  G GT+KK+AK  AAE  + IL       F VP   P  P    + K 
Sbjct: 238 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 291

Query: 124 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 178
            +   G  +++         E     E G ++K +   +  L S  +   G         
Sbjct: 292 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 344

Query: 179 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 237
           QA   +       F+  +P     ++T ++   L     S       K N+    +   P
Sbjct: 345 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 404

Query: 238 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 297
            T   + L  +++ QGF + Y D  + + N ++  L   S+ P  + HG G    +    
Sbjct: 405 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 463

Query: 298 AAHNALQYL 306
           AA N L+ L
Sbjct: 464 AALNILKLL 472


>gi|82659087 staufen isoform b [Homo sapiens]
          Length = 577

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 12/168 (7%)

Query: 33  KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 91
           K+ I  + E  +K +N+PV +E  R     H+  F  +V+VG+    GEG SKK++K  A
Sbjct: 183 KSEISQVFEIALK-RNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNA 241

Query: 92  AEAAINILK----------ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWR 141
           A A +  LK              I       + P  S +    +NPI  L ++      +
Sbjct: 242 AIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEK 301

Query: 142 LPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFL 189
            PEYTL  E G   +RE+    ++ +    G G +KK AKRNAAE  L
Sbjct: 302 EPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 349



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 50/180 (27%), Positives = 81/180 (45%), Gaps = 14/180 (7%)

Query: 23  LGKMITAKPGK--TPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRV--TVGDITCT 78
           LGK    KP    + +Q  + Y M+    P     R      VP   ++V  +VG     
Sbjct: 84  LGKKPMYKPVDPYSRMQSTYNYNMRGGAYP----PRYFYPFPVPPLLYQVELSVGGQQFN 139

Query: 79  GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHH 138
           G+G +++ AKH AA  A+ IL+        +P+ L  +  +  +  LN     Q   I  
Sbjct: 140 GKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRESEEENLNKSEISQVFEIAL 194

Query: 139 GWRLP-EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISP 197
              LP  + +++E GP H + + T   +  F+  G+G SKK +K+NAA   L +   + P
Sbjct: 195 KRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPP 254



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)

Query: 66  FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 123
           F  +V VG+ T  G GT+KK+AK  AAE  + IL       F VP   P  P    + K 
Sbjct: 319 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 372

Query: 124 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 178
            +   G  +++         E     E G ++K +   +  L S  +   G         
Sbjct: 373 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 425

Query: 179 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 237
           QA   +       F+  +P     ++T ++   L     S       K N+    +   P
Sbjct: 426 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 485

Query: 238 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 297
            T   + L  +++ QGF + Y D  + + N ++  L   S+ P  + HG G    +    
Sbjct: 486 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 544

Query: 298 AAHNALQYL 306
           AA N L+ L
Sbjct: 545 AALNILKLL 553


>gi|82659085 staufen isoform a [Homo sapiens]
          Length = 496

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 12/168 (7%)

Query: 33  KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 91
           K+ I  + E  +K +N+PV +E  R     H+  F  +V+VG+    GEG SKK++K  A
Sbjct: 102 KSEISQVFEIALK-RNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNA 160

Query: 92  AEAAINILK----------ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWR 141
           A A +  LK              I       + P  S +    +NPI  L ++      +
Sbjct: 161 AIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEK 220

Query: 142 LPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFL 189
            PEYTL  E G   +RE+    ++ +    G G +KK AKRNAAE  L
Sbjct: 221 EPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 268



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 50/180 (27%), Positives = 81/180 (45%), Gaps = 14/180 (7%)

Query: 23  LGKMITAKPGK--TPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRV--TVGDITCT 78
           LGK    KP    + +Q  + Y M+    P     R      VP   ++V  +VG     
Sbjct: 3   LGKKPMYKPVDPYSRMQSTYNYNMRGGAYP----PRYFYPFPVPPLLYQVELSVGGQQFN 58

Query: 79  GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHH 138
           G+G +++ AKH AA  A+ IL+        +P+ L  +  +  +  LN     Q   I  
Sbjct: 59  GKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRESEEENLNKSEISQVFEIAL 113

Query: 139 GWRLP-EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISP 197
              LP  + +++E GP H + + T   +  F+  G+G SKK +K+NAA   L +   + P
Sbjct: 114 KRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPP 173



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)

Query: 66  FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 123
           F  +V VG+ T  G GT+KK+AK  AAE  + IL       F VP   P  P    + K 
Sbjct: 238 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 291

Query: 124 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 178
            +   G  +++         E     E G ++K +   +  L S  +   G         
Sbjct: 292 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 344

Query: 179 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 237
           QA   +       F+  +P     ++T ++   L     S       K N+    +   P
Sbjct: 345 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 404

Query: 238 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 297
            T   + L  +++ QGF + Y D  + + N ++  L   S+ P  + HG G    +    
Sbjct: 405 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 463

Query: 298 AAHNALQYL 306
           AA N L+ L
Sbjct: 464 AALNILKLL 472


>gi|82659083 staufen isoform a [Homo sapiens]
          Length = 496

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 12/168 (7%)

Query: 33  KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 91
           K+ I  + E  +K +N+PV +E  R     H+  F  +V+VG+    GEG SKK++K  A
Sbjct: 102 KSEISQVFEIALK-RNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNA 160

Query: 92  AEAAINILK----------ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWR 141
           A A +  LK              I       + P  S +    +NPI  L ++      +
Sbjct: 161 AIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEK 220

Query: 142 LPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFL 189
            PEYTL  E G   +RE+    ++ +    G G +KK AKRNAAE  L
Sbjct: 221 EPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 268



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 50/180 (27%), Positives = 81/180 (45%), Gaps = 14/180 (7%)

Query: 23  LGKMITAKPGK--TPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRV--TVGDITCT 78
           LGK    KP    + +Q  + Y M+    P     R      VP   ++V  +VG     
Sbjct: 3   LGKKPMYKPVDPYSRMQSTYNYNMRGGAYP----PRYFYPFPVPPLLYQVELSVGGQQFN 58

Query: 79  GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHH 138
           G+G +++ AKH AA  A+ IL+        +P+ L  +  +  +  LN     Q   I  
Sbjct: 59  GKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRESEEENLNKSEISQVFEIAL 113

Query: 139 GWRLP-EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISP 197
              LP  + +++E GP H + + T   +  F+  G+G SKK +K+NAA   L +   + P
Sbjct: 114 KRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPP 173



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)

Query: 66  FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 123
           F  +V VG+ T  G GT+KK+AK  AAE  + IL       F VP   P  P    + K 
Sbjct: 238 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 291

Query: 124 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 178
            +   G  +++         E     E G ++K +   +  L S  +   G         
Sbjct: 292 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 344

Query: 179 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 237
           QA   +       F+  +P     ++T ++   L     S       K N+    +   P
Sbjct: 345 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 404

Query: 238 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 297
            T   + L  +++ QGF + Y D  + + N ++  L   S+ P  + HG G    +    
Sbjct: 405 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 463

Query: 298 AAHNALQYL 306
           AA N L+ L
Sbjct: 464 AALNILKLL 472


>gi|82659091 staufen isoform c [Homo sapiens]
          Length = 502

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 10/153 (6%)

Query: 47  KNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILK------ 100
           ++ P+ +  R     H+  F  +V+VG+    GEG SKK++K  AA A +  LK      
Sbjct: 122 ESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLP 181

Query: 101 ----ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHK 156
                   I       + P  S +    +NPI  L ++      + PEYTL  E G   +
Sbjct: 182 AVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRR 241

Query: 157 REYTTICRLESFMETGKGASKKQAKRNAAEKFL 189
           RE+    ++ +    G G +KK AKRNAAE  L
Sbjct: 242 REFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 274



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 50/186 (26%), Positives = 84/186 (45%), Gaps = 20/186 (10%)

Query: 23  LGKMITAKPGK--TPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRV--TVGDITCT 78
           LGK    KP    + +Q  + Y M+    P     R      VP   ++V  +VG     
Sbjct: 3   LGKKPMYKPVDPYSRMQSTYNYNMRGGAYP----PRYFYPFPVPPLLYQVELSVGGQQFN 58

Query: 79  GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNP--IGSLQELAI 136
           G+G +++ AKH AA  A+ IL+        +P+ L  +  +  +  LN   I  + E+A+
Sbjct: 59  GKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRESEEENLNKSEISQVFEIAL 113

Query: 137 HHGWRL-----PEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAK 191
                +     P   +++E GP H + + T   +  F+  G+G SKK +K+NAA   L +
Sbjct: 114 KRNLPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEE 173

Query: 192 FSNISP 197
              + P
Sbjct: 174 LKKLPP 179



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)

Query: 66  FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 123
           F  +V VG+ T  G GT+KK+AK  AAE  + IL       F VP   P  P    + K 
Sbjct: 244 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 297

Query: 124 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 178
            +   G  +++         E     E G ++K +   +  L S  +   G         
Sbjct: 298 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 350

Query: 179 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 237
           QA   +       F+  +P     ++T ++   L     S       K N+    +   P
Sbjct: 351 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 410

Query: 238 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 297
            T   + L  +++ QGF + Y D  + + N ++  L   S+ P  + HG G    +    
Sbjct: 411 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 469

Query: 298 AAHNALQYL 306
           AA N L+ L
Sbjct: 470 AALNILKLL 478


>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
           sapiens]
          Length = 1181

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 47/160 (29%), Positives = 69/160 (43%), Gaps = 3/160 (1%)

Query: 32  GKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTG-EGTSKKLAKHR 90
           GK+P+  L E   K  N   +     +   H P F + V VG  T       SKK+AK  
Sbjct: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671

Query: 91  AAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQE 150
           AAE A+  L   A+   A  + +            NP+G L E A  HG+   E+ L  +
Sbjct: 672 AAEEAMKALHGEATNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHGF-AAEFKLVDQ 730

Query: 151 GGPAHKREYTTICRLES-FMETGKGASKKQAKRNAAEKFL 189
            GP H+ ++    ++   +       SKKQ K+ AA+  L
Sbjct: 731 SGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAAL 770


>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
           sapiens]
          Length = 931

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 59/216 (27%), Positives = 87/216 (40%), Gaps = 26/216 (12%)

Query: 32  GKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTG-EGTSKKLAKHR 90
           GK+P+  L E   K  N   +     +   H P F + V VG  T       SKK+AK  
Sbjct: 317 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 376

Query: 91  AAEAAINILKANASICFAV---PDPLMPD---------PSKQPKN-------QLNPIGSL 131
           AAE A+  L   A+   A    P+ ++ +         P+K  K          NP+G L
Sbjct: 377 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGL 436

Query: 132 QELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLES-FMETGKGASKKQAKRNAAEK--- 187
            E A  HG+   E+ L  + GP H+ ++    ++   +       SKKQ K+ AA+    
Sbjct: 437 LEYARSHGF-AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALR 495

Query: 188 -FLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSP 222
             + +           +T V G SL  T   L  SP
Sbjct: 496 VLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSP 531


>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
           sapiens]
          Length = 1226

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 59/216 (27%), Positives = 87/216 (40%), Gaps = 26/216 (12%)

Query: 32  GKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTG-EGTSKKLAKHR 90
           GK+P+  L E   K  N   +     +   H P F + V VG  T       SKK+AK  
Sbjct: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671

Query: 91  AAEAAINILKANASICFAV---PDPLMPD---------PSKQPKN-------QLNPIGSL 131
           AAE A+  L   A+   A    P+ ++ +         P+K  K          NP+G L
Sbjct: 672 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGL 731

Query: 132 QELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLES-FMETGKGASKKQAKRNAAEK--- 187
            E A  HG+   E+ L  + GP H+ ++    ++   +       SKKQ K+ AA+    
Sbjct: 732 LEYARSHGF-AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALR 790

Query: 188 -FLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSP 222
             + +           +T V G SL  T   L  SP
Sbjct: 791 VLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSP 826


>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
           sapiens]
          Length = 1200

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 51/179 (28%), Positives = 76/179 (42%), Gaps = 22/179 (12%)

Query: 32  GKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTG-EGTSKKLAKHR 90
           GK+P+  L E   K  N   +     +   H P F + V VG  T       SKK+AK  
Sbjct: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671

Query: 91  AAEAAINILKANASICFAV---PDPLMPD---------PSKQPKN-------QLNPIGSL 131
           AAE A+  L   A+   A    P+ ++ +         P+K  K          NP+G L
Sbjct: 672 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGL 731

Query: 132 QELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLES-FMETGKGASKKQAKRNAAEKFL 189
            E A  HG+   E+ L  + GP H+ ++    ++   +       SKKQ K+ AA+  L
Sbjct: 732 LEYARSHGF-AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAAL 789


>gi|38488720 DiGeorge syndrome critical region gene 8 [Homo sapiens]
          Length = 773

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 19/97 (19%)

Query: 32  GKTPIQVLHEYGMKTKNI-PVY---ECERSDVQIHVPTFTFRVTVGDITC-TGEGTSKKL 86
           GK+ + +LHEY  +   + PVY   ECE          F   VT+  +T  +G  +SKKL
Sbjct: 509 GKSEVCILHEYMQRVLKVRPVYNFFECENPS-----EPFGASVTIDGVTYGSGTASSKKL 563

Query: 87  AKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKN 123
           AK++AA A + IL         +PD +     ++PK+
Sbjct: 564 AKNKAARATLEIL---------IPDFVKQTSEEKPKD 591


>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
           sapiens]
          Length = 674

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 16/96 (16%)

Query: 110 PDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFM 169
           P P++P  +    N++ P   LQ            YTL  + GP H   +     +   +
Sbjct: 74  PGPVLPKNALMQLNEIKP--GLQ------------YTLLSQTGPVHAPLFVMSVEVNGQV 119

Query: 170 ETGKGASKKQAKRNAAEKFLAKFSNI--SPENHISL 203
             G G +KK+AK +AAEK L  F     + E H+++
Sbjct: 120 FEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAM 155



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 4/65 (6%)

Query: 32  GKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 91
           GK P+ +L+E     K    Y+      + H  +F   V V      G G +KKLAK RA
Sbjct: 233 GKNPVMILNELRPGLK----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARA 288

Query: 92  AEAAI 96
           A++A+
Sbjct: 289 AQSAL 293



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 5/84 (5%)

Query: 112 PLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMET 171
           PL   P   P +  NP+  L EL    G +   Y    E G +H + +     ++     
Sbjct: 221 PLPVLPPFPPPSGKNPVMILNEL--RPGLK---YDFLSESGESHAKSFVMSVVVDGQFFE 275

Query: 172 GKGASKKQAKRNAAEKFLAKFSNI 195
           G G +KK AK  AA+  LA   N+
Sbjct: 276 GSGRNKKLAKARAAQSALAAIFNL 299



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 15/36 (41%), Positives = 18/36 (50%)

Query: 61  IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAI 96
           +H P F   V V      G G +KK AK  AAE A+
Sbjct: 104 VHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKAL 139


>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
           sapiens]
          Length = 714

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 16/96 (16%)

Query: 110 PDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFM 169
           P P++P  +    N++ P   LQ            YTL  + GP H   +     +   +
Sbjct: 74  PGPVLPKNALMQLNEIKP--GLQ------------YTLLSQTGPVHAPLFVMSVEVNGQV 119

Query: 170 ETGKGASKKQAKRNAAEKFLAKFSNI--SPENHISL 203
             G G +KK+AK +AAEK L  F     + E H+++
Sbjct: 120 FEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAM 155



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 4/65 (6%)

Query: 32  GKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 91
           GK P+ +L+E     K    Y+      + H  +F   V V      G G +KKLAK RA
Sbjct: 233 GKNPVMILNELRPGLK----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARA 288

Query: 92  AEAAI 96
           A++A+
Sbjct: 289 AQSAL 293



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 5/84 (5%)

Query: 112 PLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMET 171
           PL   P   P +  NP+  L EL    G +   Y    E G +H + +     ++     
Sbjct: 221 PLPVLPPFPPPSGKNPVMILNEL--RPGLK---YDFLSESGESHAKSFVMSVVVDGQFFE 275

Query: 172 GKGASKKQAKRNAAEKFLAKFSNI 195
           G G +KK AK  AA+  LA   N+
Sbjct: 276 GSGRNKKLAKARAAQSALAAIFNL 299



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 15/36 (41%), Positives = 18/36 (50%)

Query: 61  IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAI 96
           +H P F   V V      G G +KK AK  AAE A+
Sbjct: 104 VHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKAL 139


>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
           sapiens]
          Length = 741

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 16/96 (16%)

Query: 110 PDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFM 169
           P P++P  +    N++ P   LQ            YTL  + GP H   +     +   +
Sbjct: 74  PGPVLPKNALMQLNEIKP--GLQ------------YTLLSQTGPVHAPLFVMSVEVNGQV 119

Query: 170 ETGKGASKKQAKRNAAEKFLAKFSNI--SPENHISL 203
             G G +KK+AK +AAEK L  F     + E H+++
Sbjct: 120 FEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAM 155



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 4/65 (6%)

Query: 32  GKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 91
           GK P+ +L+E     K    Y+      + H  +F   V V      G G +KKLAK RA
Sbjct: 233 GKNPVMILNELRPGLK----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARA 288

Query: 92  AEAAI 96
           A++A+
Sbjct: 289 AQSAL 293



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 5/84 (5%)

Query: 112 PLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMET 171
           PL   P   P +  NP+  L EL    G +   Y    E G +H + +     ++     
Sbjct: 221 PLPVLPPFPPPSGKNPVMILNEL--RPGLK---YDFLSESGESHAKSFVMSVVVDGQFFE 275

Query: 172 GKGASKKQAKRNAAEKFLAKFSNI 195
           G G +KK AK  AA+  LA   N+
Sbjct: 276 GSGRNKKLAKARAAQSALAAIFNL 299



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 15/36 (41%), Positives = 18/36 (50%)

Query: 61  IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAI 96
           +H P F   V V      G G +KK AK  AAE A+
Sbjct: 104 VHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKAL 139


>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
           sapiens]
          Length = 701

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 16/96 (16%)

Query: 110 PDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFM 169
           P P++P  +    N++ P   LQ            YTL  + GP H   +     +   +
Sbjct: 74  PGPVLPKNALMQLNEIKP--GLQ------------YTLLSQTGPVHAPLFVMSVEVNGQV 119

Query: 170 ETGKGASKKQAKRNAAEKFLAKFSNI--SPENHISL 203
             G G +KK+AK +AAEK L  F     + E H+++
Sbjct: 120 FEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAM 155



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 4/65 (6%)

Query: 32  GKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 91
           GK P+ +L+E     K    Y+      + H  +F   V V      G G +KKLAK RA
Sbjct: 233 GKNPVMILNELRPGLK----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARA 288

Query: 92  AEAAI 96
           A++A+
Sbjct: 289 AQSAL 293



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 5/84 (5%)

Query: 112 PLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMET 171
           PL   P   P +  NP+  L EL    G +   Y    E G +H + +     ++     
Sbjct: 221 PLPVLPPFPPPSGKNPVMILNEL--RPGLK---YDFLSESGESHAKSFVMSVVVDGQFFE 275

Query: 172 GKGASKKQAKRNAAEKFLAKFSNI 195
           G G +KK AK  AA+  LA   N+
Sbjct: 276 GSGRNKKLAKARAAQSALAAIFNL 299



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 15/36 (41%), Positives = 18/36 (50%)

Query: 61  IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAI 96
           +H P F   V V      G G +KK AK  AAE A+
Sbjct: 104 VHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKAL 139


>gi|208431829 eukaryotic translation initiation factor 2-alpha
           kinase 2 isoform b [Homo sapiens]
          Length = 510

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 51/191 (26%), Positives = 82/191 (42%), Gaps = 14/191 (7%)

Query: 36  IQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTV-GDITCTGEGTSKKLAKHRAAEA 94
           ++ L+ Y  K   +  Y+   +    H   FTF+V + G     GEG SKK AK+ AA+ 
Sbjct: 11  MEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKL 70

Query: 95  AINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQE---G 151
           A+ IL  N       P  L    S +  +  N IG +  +A     +    T++ E    
Sbjct: 71  AVEIL--NKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIA-----QKKRLTVNYEQCAS 123

Query: 152 GPAHKREYTTICRL-ESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHS 210
           G      +   C++ +     G G++K++AK+ AA+  LA    +S E  +    +   S
Sbjct: 124 GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAK--LAYLQILSEETSVKSDYLSSGS 181

Query: 211 LGCTWHSLRNS 221
              T  S  NS
Sbjct: 182 FATTCESQSNS 192


>gi|208431827 eukaryotic translation initiation factor 2-alpha
           kinase 2 isoform a [Homo sapiens]
          Length = 551

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 51/191 (26%), Positives = 82/191 (42%), Gaps = 14/191 (7%)

Query: 36  IQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTV-GDITCTGEGTSKKLAKHRAAEA 94
           ++ L+ Y  K   +  Y+   +    H   FTF+V + G     GEG SKK AK+ AA+ 
Sbjct: 11  MEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKL 70

Query: 95  AINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQE---G 151
           A+ IL  N       P  L    S +  +  N IG +  +A     +    T++ E    
Sbjct: 71  AVEIL--NKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIA-----QKKRLTVNYEQCAS 123

Query: 152 GPAHKREYTTICRL-ESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHS 210
           G      +   C++ +     G G++K++AK+ AA+  LA    +S E  +    +   S
Sbjct: 124 GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAK--LAYLQILSEETSVKSDYLSSGS 181

Query: 211 LGCTWHSLRNS 221
              T  S  NS
Sbjct: 182 FATTCESQSNS 192


>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
           2 isoform a [Homo sapiens]
          Length = 551

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 51/191 (26%), Positives = 82/191 (42%), Gaps = 14/191 (7%)

Query: 36  IQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTV-GDITCTGEGTSKKLAKHRAAEA 94
           ++ L+ Y  K   +  Y+   +    H   FTF+V + G     GEG SKK AK+ AA+ 
Sbjct: 11  MEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKL 70

Query: 95  AINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQE---G 151
           A+ IL  N       P  L    S +  +  N IG +  +A     +    T++ E    
Sbjct: 71  AVEIL--NKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIA-----QKKRLTVNYEQCAS 123

Query: 152 GPAHKREYTTICRL-ESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHS 210
           G      +   C++ +     G G++K++AK+ AA+  LA    +S E  +    +   S
Sbjct: 124 GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAK--LAYLQILSEETSVKSDYLSSGS 181

Query: 211 LGCTWHSLRNS 221
              T  S  NS
Sbjct: 182 FATTCESQSNS 192


>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
          Length = 739

 Score = 36.2 bits (82), Expect = 0.039
 Identities = 19/48 (39%), Positives = 24/48 (50%)

Query: 61  IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFA 108
           +H P F   V V  +T  G G +KK AK RAAE A+       + C A
Sbjct: 151 VHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQA 198



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 18/48 (37%), Positives = 25/48 (52%)

Query: 52  YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINIL 99
           Y C     +    +F   V+V   T  G G SKKLA+ +AA+AA+  L
Sbjct: 292 YVCLAEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQEL 339



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 15/49 (30%), Positives = 21/49 (42%)

Query: 144 EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKF 192
           +Y    + GP H   +     +      G G +KK+AK  AAE  L  F
Sbjct: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSF 189


>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
           sapiens]
          Length = 690

 Score = 35.4 bits (80), Expect = 0.066
 Identities = 41/173 (23%), Positives = 61/173 (35%), Gaps = 33/173 (19%)

Query: 61  IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAIN----------------------- 97
           +H P FT  V V   +    G SKK AK   A   +                        
Sbjct: 427 VHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486

Query: 98  ----ILKANASICFAVPDPLMPDPSKQPKNQ---LNPIGSLQELAIHHGWRLPEYTLSQE 150
                + A A +  AV  P    PS     Q   L   G    + ++   R  +Y L  E
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLKYELISE 546

Query: 151 GGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISL 203
            G +H + +     ++     G G++KK AK  AA   LA    + P+  ++L
Sbjct: 547 TGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAA---LAALEKLFPDTPLAL 596



 Score = 32.3 bits (72), Expect = 0.56
 Identities = 39/130 (30%), Positives = 52/130 (40%), Gaps = 20/130 (15%)

Query: 27  ITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKL 86
           I  K GK P+  L+E     K    YE        H   F   V V      G G++KK+
Sbjct: 520 ILTKHGKNPVMELNEKRRGLK----YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKV 575

Query: 87  AKHRAAEAAINILKANASICFAVPD-PLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEY 145
           AK  AA AA+  L          PD PL  D +K+ +  +   G  +  A  H    P +
Sbjct: 576 AKAYAALAALEKL---------FPDTPLALDANKKKRAPVPVRGGPKFAAKPHN---PGF 623

Query: 146 TLSQEGGPAH 155
            +   GGP H
Sbjct: 624 GM---GGPMH 630


>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
           sapiens]
          Length = 702

 Score = 35.4 bits (80), Expect = 0.066
 Identities = 41/173 (23%), Positives = 61/173 (35%), Gaps = 33/173 (19%)

Query: 61  IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAIN----------------------- 97
           +H P FT  V V   +    G SKK AK   A   +                        
Sbjct: 427 VHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486

Query: 98  ----ILKANASICFAVPDPLMPDPSKQPKNQ---LNPIGSLQELAIHHGWRLPEYTLSQE 150
                + A A +  AV  P    PS     Q   L   G    + ++   R  +Y L  E
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLKYELISE 546

Query: 151 GGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISL 203
            G +H + +     ++     G G++KK AK  AA   LA    + P+  ++L
Sbjct: 547 TGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAA---LAALEKLFPDTPLAL 596



 Score = 32.3 bits (72), Expect = 0.56
 Identities = 39/130 (30%), Positives = 52/130 (40%), Gaps = 20/130 (15%)

Query: 27  ITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKL 86
           I  K GK P+  L+E     K    YE        H   F   V V      G G++KK+
Sbjct: 520 ILTKHGKNPVMELNEKRRGLK----YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKV 575

Query: 87  AKHRAAEAAINILKANASICFAVPD-PLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEY 145
           AK  AA AA+  L          PD PL  D +K+ +  +   G  +  A  H    P +
Sbjct: 576 AKAYAALAALEKL---------FPDTPLALDANKKKRAPVPVRGGPKFAAKPHN---PGF 623

Query: 146 TLSQEGGPAH 155
            +   GGP H
Sbjct: 624 GM---GGPMH 630


>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
           sapiens]
          Length = 894

 Score = 35.4 bits (80), Expect = 0.066
 Identities = 41/173 (23%), Positives = 61/173 (35%), Gaps = 33/173 (19%)

Query: 61  IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAIN----------------------- 97
           +H P FT  V V   +    G SKK AK   A   +                        
Sbjct: 427 VHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486

Query: 98  ----ILKANASICFAVPDPLMPDPSKQPKNQ---LNPIGSLQELAIHHGWRLPEYTLSQE 150
                + A A +  AV  P    PS     Q   L   G    + ++   R  +Y L  E
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLKYELISE 546

Query: 151 GGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISL 203
            G +H + +     ++     G G++KK AK  AA   LA    + P+  ++L
Sbjct: 547 TGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAA---LAALEKLFPDTPLAL 596



 Score = 32.3 bits (72), Expect = 0.56
 Identities = 39/130 (30%), Positives = 52/130 (40%), Gaps = 20/130 (15%)

Query: 27  ITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKL 86
           I  K GK P+  L+E     K    YE        H   F   V V      G G++KK+
Sbjct: 520 ILTKHGKNPVMELNEKRRGLK----YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKV 575

Query: 87  AKHRAAEAAINILKANASICFAVPD-PLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEY 145
           AK  AA AA+  L          PD PL  D +K+ +  +   G  +  A  H    P +
Sbjct: 576 AKAYAALAALEKL---------FPDTPLALDANKKKRAPVPVRGGPKFAAKPHN---PGF 623

Query: 146 TLSQEGGPAH 155
            +   GGP H
Sbjct: 624 GM---GGPMH 630


>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
           sapiens]
          Length = 706

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 42/177 (23%), Positives = 62/177 (35%), Gaps = 37/177 (20%)

Query: 61  IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAIN----------------------- 97
           +H P FT  V V   +    G SKK AK   A   +                        
Sbjct: 427 VHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486

Query: 98  ----ILKANASICFAVPDPLMPDPS-------KQPKNQLNPIGSLQELAIHHGWRLPEYT 146
                + A A +  AV  P    PS       KQ    L   G    + ++   R  +Y 
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRRGLKYE 546

Query: 147 LSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISL 203
           L  E G +H + +     ++     G G++KK AK  AA   LA    + P+  ++L
Sbjct: 547 LISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAA---LAALEKLFPDTPLAL 600



 Score = 32.3 bits (72), Expect = 0.56
 Identities = 39/130 (30%), Positives = 52/130 (40%), Gaps = 20/130 (15%)

Query: 27  ITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKL 86
           I  K GK P+  L+E     K    YE        H   F   V V      G G++KK+
Sbjct: 524 ILTKHGKNPVMELNEKRRGLK----YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKV 579

Query: 87  AKHRAAEAAINILKANASICFAVPD-PLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEY 145
           AK  AA AA+  L          PD PL  D +K+ +  +   G  +  A  H    P +
Sbjct: 580 AKAYAALAALEKL---------FPDTPLALDANKKKRAPVPVRGGPKFAAKPHN---PGF 627

Query: 146 TLSQEGGPAH 155
            +   GGP H
Sbjct: 628 GM---GGPMH 634


>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
           sapiens]
          Length = 898

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 42/177 (23%), Positives = 62/177 (35%), Gaps = 37/177 (20%)

Query: 61  IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAIN----------------------- 97
           +H P FT  V V   +    G SKK AK   A   +                        
Sbjct: 427 VHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486

Query: 98  ----ILKANASICFAVPDPLMPDPS-------KQPKNQLNPIGSLQELAIHHGWRLPEYT 146
                + A A +  AV  P    PS       KQ    L   G    + ++   R  +Y 
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRRGLKYE 546

Query: 147 LSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISL 203
           L  E G +H + +     ++     G G++KK AK  AA   LA    + P+  ++L
Sbjct: 547 LISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAA---LAALEKLFPDTPLAL 600



 Score = 32.3 bits (72), Expect = 0.56
 Identities = 39/130 (30%), Positives = 52/130 (40%), Gaps = 20/130 (15%)

Query: 27  ITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKL 86
           I  K GK P+  L+E     K    YE        H   F   V V      G G++KK+
Sbjct: 524 ILTKHGKNPVMELNEKRRGLK----YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKV 579

Query: 87  AKHRAAEAAINILKANASICFAVPD-PLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEY 145
           AK  AA AA+  L          PD PL  D +K+ +  +   G  +  A  H    P +
Sbjct: 580 AKAYAALAALEKL---------FPDTPLALDANKKKRAPVPVRGGPKFAAKPHN---PGF 627

Query: 146 TLSQEGGPAH 155
            +   GGP H
Sbjct: 628 GM---GGPMH 634


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,349,640
Number of Sequences: 37866
Number of extensions: 541313
Number of successful extensions: 1516
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1402
Number of HSP's gapped (non-prelim): 94
length of query: 313
length of database: 18,247,518
effective HSP length: 102
effective length of query: 211
effective length of database: 14,385,186
effective search space: 3035274246
effective search space used: 3035274246
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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