BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4505463 contactin associated protein 1 precursor [Homo sapiens] (1384 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4505463 contactin associated protein 1 precursor [Homo sapiens] 2930 0.0 gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi... 1145 0.0 gi|18640734 contactin associated protein-like 5 [Homo sapiens] 938 0.0 gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap... 931 0.0 gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1... 884 0.0 gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap... 882 0.0 gi|47519929 cell recognition molecule CASPR3 [Homo sapiens] 879 0.0 gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2... 708 0.0 gi|239743797 PREDICTED: similar to cell recognition molecule CAS... 344 4e-94 gi|239743729 PREDICTED: similar to contactin associated protein-... 246 1e-64 gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens] 134 8e-31 gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens] 133 1e-30 gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens] 131 5e-30 gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens] 130 7e-30 gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens] 115 3e-25 gi|169184330 PREDICTED: novel protein similar to contactin assoc... 103 1e-21 gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 74 7e-13 gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 72 4e-12 gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 70 1e-11 gi|10518506 coagulation factor VIII isoform b precursor [Homo sa... 70 1e-11 gi|4503647 coagulation factor VIII isoform a precursor [Homo sap... 70 1e-11 gi|105990535 coagulation factor V precursor [Homo sapiens] 69 4e-11 gi|10835083 X-linked juvenile retinoschisis protein precursor [H... 69 4e-11 gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 68 5e-11 gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 68 7e-11 gi|239758135 PREDICTED: similar to cell recognition molecule CAS... 67 1e-10 gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 66 3e-10 gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 66 3e-10 gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 66 3e-10 gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 66 3e-10 >gi|4505463 contactin associated protein 1 precursor [Homo sapiens] Length = 1384 Score = 2930 bits (7597), Expect = 0.0 Identities = 1384/1384 (100%), Positives = 1384/1384 (100%) Query: 1 MMHLRLFCILLAAVSGAEGWGYYGCDEELVGPLYARSLGASSYYSLLTAPRFARLHGISG 60 MMHLRLFCILLAAVSGAEGWGYYGCDEELVGPLYARSLGASSYYSLLTAPRFARLHGISG Sbjct: 1 MMHLRLFCILLAAVSGAEGWGYYGCDEELVGPLYARSLGASSYYSLLTAPRFARLHGISG 60 Query: 61 WSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHN 120 WSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHN Sbjct: 61 WSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHN 120 Query: 121 STFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGD 180 STFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGD Sbjct: 121 STFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGD 180 Query: 181 DAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGS 240 DAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGS Sbjct: 181 DAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGS 240 Query: 241 SPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTE 300 SPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTE Sbjct: 241 SPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTE 300 Query: 301 MFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVP 360 MFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVP Sbjct: 301 MFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVP 360 Query: 361 HPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVN 420 HPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVN Sbjct: 361 HPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVN 420 Query: 421 VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGT 480 VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGT Sbjct: 421 VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGT 480 Query: 481 SYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGI 540 SYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGI Sbjct: 481 SYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGI 540 Query: 541 TDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTI 600 TDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTI Sbjct: 541 TDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTI 600 Query: 601 DPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVS 660 DPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVS Sbjct: 601 DPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVS 660 Query: 661 ALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLD 720 ALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLD Sbjct: 661 ALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLD 720 Query: 721 RSCVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYG 780 RSCVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYG Sbjct: 721 RSCVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYG 780 Query: 781 DRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRV 840 DRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRV Sbjct: 781 DRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRV 840 Query: 841 ELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRP 900 ELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRP Sbjct: 841 ELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRP 900 Query: 901 MPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGH 960 MPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGH Sbjct: 901 MPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGH 960 Query: 961 CAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSA 1020 CAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSA Sbjct: 961 CAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSA 1020 Query: 1021 AREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVT 1080 AREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVT Sbjct: 1021 AREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVT 1080 Query: 1081 GEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTD 1140 GEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTD Sbjct: 1081 GEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTD 1140 Query: 1141 GQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQR 1200 GQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQR Sbjct: 1141 GQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQR 1200 Query: 1201 YNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEV 1260 YNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEV Sbjct: 1201 YNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEV 1260 Query: 1261 PPELDPWYLPPDFPYYHDEGWVAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEP 1320 PPELDPWYLPPDFPYYHDEGWVAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEP Sbjct: 1261 PPELDPWYLPPDFPYYHDEGWVAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEP 1320 Query: 1321 KAAHEYHPGSKPPLPTSGPAQVPTPTAAPNQAPASAPAPAPTPAPAPGPRDQNLPQILEE 1380 KAAHEYHPGSKPPLPTSGPAQVPTPTAAPNQAPASAPAPAPTPAPAPGPRDQNLPQILEE Sbjct: 1321 KAAHEYHPGSKPPLPTSGPAQVPTPTAAPNQAPASAPAPAPTPAPAPGPRDQNLPQILEE 1380 Query: 1381 SRSE 1384 SRSE Sbjct: 1381 SRSE 1384 >gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapiens] Length = 1331 Score = 1145 bits (2961), Expect = 0.0 Identities = 577/1321 (43%), Positives = 824/1321 (62%), Gaps = 76/1321 (5%) Query: 25 CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81 CDE LV L + +SS S +P +A+++ G GWSP D WLQ+D + + Sbjct: 35 CDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQ 94 Query: 82 IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141 I A+ATQG ++S DWVT+Y +LY D +W P++Q G+ F GN+N VVRH+L Sbjct: 95 ISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPI 154 Query: 142 TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201 ARY+RIVPL WN G+IGLR+ +YGC Y AD++ FDG + YRF ++L DV A Sbjct: 155 IARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIAL 214 Query: 202 SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261 +FKT E +G++LH EG QGDY+TLEL+ A L+L ++LGS+ + P GHT+V G +L+D Sbjct: 215 NFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274 Query: 262 HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321 HWH V ++R GR +N TLD +Q F NG+F+ L+LD E+ GG+ + + + + R NF+ Sbjct: 275 HWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFK 334 Query: 322 GCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRG 381 GC+E++ +N VNI DLA R+ + G ++F C++P P+ F ++++VPG + Sbjct: 335 GCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVFFNAT-SYLEVPGRLNQD 393 Query: 382 RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQ--VNVSIAQSGRKKLQFAAGYRL 439 +VSF+FRTW+ GLL+FS D LG+VE+ L+E + V+++I Q+ ++ ++G L Sbjct: 394 LFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGL 453 Query: 440 NDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSN 499 NDG WHEV F+A+EN A+++ID E + VR + PL ++TG YFFGG + Sbjct: 454 NDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVL 513 Query: 500 QTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSW 559 Q +F GCM+L++VD QLVNL V R+ G +A V D C I DRC PN CEH G+C Q+W Sbjct: 514 QPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTW 573 Query: 560 DDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRE 619 D F C C+ TGY G TCH +Y+ SCEAY+ G+TS + IDPDGSGPL P VYC++ E Sbjct: 574 DSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTE 633 Query: 620 NRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYN 679 ++ WT+V HD T V G + E+ + + Y +AS +++SA+ +++++CEQ++ + C Sbjct: 634 DKVWTIVSHDLQMQTPVVGYNPEKYSVTQLVY-SASMDQISAITDSAEYCEQYVSYFCKM 692 Query: 680 SRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQW 739 SRLLNT G PY++W+G+ E+H+YWGGS PGIQ+CACG++R+C DP YCNCDAD QW Sbjct: 693 SRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQW 752 Query: 740 RTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISF-HTGAALRF 798 R D G L++ DHLPV+QVV+GDT+R SEA+ + PLRC GDRN WN SF + + L F Sbjct: 753 RKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHF 812 Query: 799 PPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGD 858 + S D+SFYF+T P GVFLENMG + ++++EL ++ +V F+FDVGNG Sbjct: 813 STFQGETSADISFYFKTLTPWGVFLENMG------KEDFIKLELKSATEVSFSFDVGNGP 866 Query: 859 ENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVG 918 + V S NDD+WH V AE NVKQA L+VD P +R P + + +E L+VG Sbjct: 867 VEIVVRSPT-PLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVG 925 Query: 919 SAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERY 978 A ++ F+GC+R++R+NGVTL+LE RA + G C+GHC C +GG+C+ERY Sbjct: 926 GAG-GQQGFLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERY 984 Query: 979 SYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPG 1038 Y+CDC TA+DG +CN D+G FFE G W+RYN Q+ +A S + + P Sbjct: 985 HGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAP------- 1037 Query: 1039 YIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLL 1098 D P ++ EE+ FSFST+ AP +LL Sbjct: 1038 -----DQQNSHP---------------------------DLAQEEIRFSFSTTKAPCILL 1065 Query: 1099 YVSSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLF 1156 Y+SSF D++AVL+K G+LQ+RY LG PY + R + +GQPHS+NITR + +F Sbjct: 1066 YISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIF 1125 Query: 1157 IQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFN 1216 +++D++P D+ +SPK+L+LG+V+ETG ID EI +YNTPGF+GCLS V+FN Sbjct: 1126 LKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQFN 1185 Query: 1217 NVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEVPPELDPWYL------P 1270 +APLK R + + +QGEL ESNCGA P +S + DPW+L Sbjct: 1186 QIAPLKAALR-----QTNASAHVHIQGELVESNCGASPLTLSPMSSATDPWHLDHLDSAS 1240 Query: 1271 PDFPYYHDEGWV--------AILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEPKA 1322 DFPY +G + ++G ++A ++ ++ LV R+KG+YHTNE K Sbjct: 1241 ADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKG 1300 Query: 1323 A 1323 A Sbjct: 1301 A 1301 >gi|18640734 contactin associated protein-like 5 [Homo sapiens] Length = 1306 Score = 938 bits (2424), Expect = 0.0 Identities = 510/1340 (38%), Positives = 761/1340 (56%), Gaps = 93/1340 (6%) Query: 5 RLFCILLAAVSGAEGWGY----YGCDEELVGPLYARSLGASSYYSLLTAPRFARLH---G 57 RL +L SG G Y CD+ L L + +SS + +P A+L+ G Sbjct: 6 RLTSVLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVG 63 Query: 58 ISGWSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQR 117 GWSP + WLQ+DL + I AVATQG + S DWVT Y L++ D +W + Q Sbjct: 64 TGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQE 123 Query: 118 GHNSTFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYF 177 TF GN+N +VV H L AR++R VPL WNP GKIG+R+ +YGC YK+D+ F Sbjct: 124 DSIWTFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADF 183 Query: 178 DGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMS 237 DG ++ YRF + + +L DV + FK+ + DG+L H EG +GD++TLEL+ L LH++ Sbjct: 184 DGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLN 243 Query: 238 LGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNL 297 LG S + + + G +L+DQHWH V ++R G+ VNFT+D + Q F G+ + L++ Sbjct: 244 LGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDI 303 Query: 298 DTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLD 357 D E+ GG+ + + NF GCIEN+ +N VNI DLA RR +I + G V F C + Sbjct: 304 DYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQI-YTGNVTFSCSE 362 Query: 358 PVPHPINF-GGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSE 416 P PI F +++ +PG P+ L+VSF+FRTW+ GLLL + L +G G + L+L Sbjct: 363 PQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEG 422 Query: 417 GQVNVSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLI 476 G + + I + + + G LNDG WH V+ A+ N +++DD S + I Sbjct: 423 GILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQI 482 Query: 477 RTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFD 536 +G SY+FGGCP + C + AF GCM L+ +D Q +L V+ LG ++++ D Sbjct: 483 YSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHID 542 Query: 537 TCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSG 596 C I DRC PN CEH G C QSW F C C T Y G TCH +Y++SCE YR G T+G Sbjct: 543 LCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAG 602 Query: 597 NFTIDPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASW 656 F ID DGSGPL P VYC+I E++ WT V+H+ TRV G++ E+P+ A+ Y S Sbjct: 603 FFYIDSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDY-GGSM 661 Query: 657 EEVSALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCA 716 E++ A+ + S+HCEQ + + C SRLLNT G P+++WIGR+ E+H YWGGS PG+Q+C Sbjct: 662 EQLEAVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCE 721 Query: 717 CGLDRSCVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPL 776 CGLD SC+D +CNCDAD+ +W D G L+F DHLPVTQ+VI DT+RS SEA + + PL Sbjct: 722 CGLDESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPL 781 Query: 777 RCYGDRNSWNTISFHTGAA-LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRR 835 RCYGDR WN +SF+T A+ L FP A S D+SF+F+T+A SGVFLEN+G + Sbjct: 782 RCYGDRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLG------IK 835 Query: 836 PYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRP 895 ++R+E+++ ++ FA DVGNG L V S ND++WH VRAE N+K+ L+VD+ P Sbjct: 836 DFIRLEISSPSEITFAIDVGNGPVELVVQSPSL-LNDNQWHYVRAERNLKETSLQVDNLP 894 Query: 896 WVLRPMPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSP 955 R + + ++ + L+VG +++ F+GC+R++ LNG ++LE RA + G P Sbjct: 895 RSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRP 954 Query: 956 NCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQS 1015 C GHC+ C +GG+CVE+++ Y CDC + ++GP+C ++ FE GT + Y Q Sbjct: 955 GCPGHCSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQE 1014 Query: 1016 ---ALRSAAREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGY 1072 ++ + S + + P E Sbjct: 1015 PYPVTKNISLSSSAIYTDSAPSKE------------------------------------ 1038 Query: 1073 RGPVYNVTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLG-TSPYVY 1131 ++ SF T+ AP++LL+++S +D++ VL+ +G+LQ+RY L +V+ Sbjct: 1039 ----------NIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEETHVF 1088 Query: 1132 QLTTRPVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMET 1191 + + + H + I R R L IQ+D FS V+ ++ ++L LG+V E Sbjct: 1089 TIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRV--IRSLTLGKVTEN 1146 Query: 1192 GVIDPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFR--TPRPMTAELAEALRVQGELSESN 1249 +D E+ + N GF+GC+S V++N++APLK R T P+T V G L+ES+ Sbjct: 1147 LGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVT--------VHGTLTESS 1198 Query: 1250 CGAM----PRLVSEVPPELDPWYLPPD-FPYYHDEGWVAILLGFLVA---FLLLGLVGML 1301 CG M V+ V DP+ + P + + ++G ++A F++ ++G++ Sbjct: 1199 CGFMVDSDVNAVTTVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIM 1258 Query: 1302 VLFYLQNHRYKGSYHTNEPK 1321 F Q +K S+ T++ K Sbjct: 1259 TRFLYQ---HKQSHRTSQMK 1275 >gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sapiens] Length = 1308 Score = 931 bits (2406), Expect = 0.0 Identities = 478/1244 (38%), Positives = 722/1244 (58%), Gaps = 68/1244 (5%) Query: 18 EGWGYYGCDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQI 74 E Y CD+ LV L S +SS S P FARL+ G GWSP + + WLQI Sbjct: 24 EAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQI 83 Query: 75 DLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVR 134 DL ++ + AVATQG + S +WVT Y+L++ D +W + Q F GN N +VV Sbjct: 84 DLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVY 143 Query: 135 HDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRS 194 + L AR++R +PL WNP+G+IG+R+ ++GC Y+++++ DG ++ YRF + Sbjct: 144 YRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSP 203 Query: 195 LWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSA 254 + D+ + FKT + DG+LLH EG GD++TL+L A L L ++ G + + ++ Sbjct: 204 IKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTL 263 Query: 255 GGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNL 314 G +L+DQHWH V + R G+ VNFT+D + F G+F +NLD E+ GG + A K++ Sbjct: 264 GSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEISFGG-IPAPGKSV 322 Query: 315 AYRH-NFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQ 373 ++ H NF GC+EN+ +N V+I DLA ++ +I G V+F C P P+ F +++ Sbjct: 323 SFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSSRSYLA 382 Query: 374 VPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQF 433 +P F ++ +F+FRTW+ GLLLFS L G + L LS+G++ ++ Q G+ Sbjct: 383 LPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDI 442 Query: 434 AAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASR 493 AG LNDG WH V+ A++NH +++D + + P I +G +Y+FGGCP + Sbjct: 443 TAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFG 502 Query: 494 WDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDG 553 C S F GCM L+ + G++V+L V+ LG ++++ D+CGI+DRC PN CEH G Sbjct: 503 SKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGG 562 Query: 554 RCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVV 613 C QSW F C C TGY+G TCH +Y++SCEAY+ G TSG + ID DGSGPL+PF++ Sbjct: 563 ECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLL 622 Query: 614 YCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWI 673 YC++ E AWT+++H+ TRV ++ E P+ G +Y AS E++ A N ++HCEQ Sbjct: 623 YCNMTET-AWTIIQHNGSDLTRVRNTNPENPYAGFFEYV-ASMEQLQATINRAEHCEQEF 680 Query: 674 EFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCD 733 + C SRL+N G P S+W+GR E YWGGS P +Q+C CGL+ +C+D YCNCD Sbjct: 681 TYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCD 740 Query: 734 ADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTG 793 AD+ +W D GLL + +HLPVT++VI DT R SEA + L PL C GDR+ WN+ SF T Sbjct: 741 ADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTE 800 Query: 794 AA-LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAF 852 A+ L FP S DVSF+F+T+A SGVFLEN+G ++R+EL + V F+F Sbjct: 801 ASYLHFPTFHGELSADVSFFFKTTASSGVFLENLG------IADFIRIELRSPTVVTFSF 854 Query: 853 DVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYD 912 DVGNG ++V S FND++WH VR E N+K+A L+VD +P P ++ ++ + Sbjct: 855 DVGNGPFEISVQSPT-HFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLN 913 Query: 913 QPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGG 972 L+VG ++R F+GC+R+++LNG+TL+LE RA + P C GHC+ C +GG Sbjct: 914 SQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGG 973 Query: 973 RCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPV 1032 +C ER + CDC +A+ GP+C+++I +F G+ + YN Q Sbjct: 974 KCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQE----------------- 1016 Query: 1033 PGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSS 1092 Y+ ++ + +HG ++ E + FSF T+ Sbjct: 1017 -----NYLLSKNSSSHAASFHGD---------------------MKLSREMIKFSFRTTR 1050 Query: 1093 APAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITR 1150 P++LL+VSSF ++Y++V+I +G+LQ+RY+L P V + + DGQ H I I R Sbjct: 1051 TPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINR 1110 Query: 1151 VYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCL 1210 +FI++D ++ L ++ + K+L LGR++E +D + GF+GCL Sbjct: 1111 EEGVVFIEID--DNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCL 1168 Query: 1211 SGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMP 1254 S V+ ++VAPLK P + + V G ++ES+C A P Sbjct: 1169 SAVQLSHVAPLKAALHPSHP------DPVTVTGHVTESSCMAQP 1206 >gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1 [Homo sapiens] Length = 1288 Score = 884 bits (2284), Expect = 0.0 Identities = 455/1212 (37%), Positives = 690/1212 (56%), Gaps = 60/1212 (4%) Query: 25 CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81 CD L L S +SS S P F+RL+ G GW+P + + WLQIDL ++ Sbjct: 31 CDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90 Query: 82 IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141 + AVATQG + S DWVT Y+L++ D +W + + F GN N +VV + L F Sbjct: 91 VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150 Query: 142 TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201 AR++R +PLAWNPRG+IG+R+ +YGC YK++++YFDG A+ Y + + + DV + Sbjct: 151 EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210 Query: 202 SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261 FK + +G+LLH EG G+++TLEL L+ ++ G++ + T++ G +L+DQ Sbjct: 211 KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270 Query: 262 HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321 HWH V ++ VNFT+D + F GD L+L+ E+ GG++ R R +F Sbjct: 271 HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFH 330 Query: 322 GCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRG 381 GC+EN+ +N V++ +LA + +I G V+F C P P+ F +++ +PG Sbjct: 331 GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390 Query: 382 RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLND 441 +++V+F+FRTW+ G LLF L G G L L +G++ +S+ Q+G+ AG LND Sbjct: 391 KVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLND 450 Query: 442 GFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQT 501 G WH V+F A+ +H + +DD + V+ +LI +G +Y+FGGC +S C S Sbjct: 451 GQWHSVSFSAKWSHMNVVVDDDTAVQPLVA--VLIDSGDTYYFGGCLGNSSGSGCKSPLG 508 Query: 502 AFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDD 561 F GC+ L+ + + V+ LV+ LG + ++ D+CGITDRC P+ CEH G C QSWD Sbjct: 509 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 568 Query: 562 FICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRENR 621 F C C TGY GETCH+ LY++SCEA++ G SG + ID DGSGPL PF+VYC++ + Sbjct: 569 FSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTADS 628 Query: 622 AWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSR 681 AWTVVRH + G+ P + A ++ A N ++ CEQ + C +R Sbjct: 629 AWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGTAR 688 Query: 682 LLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRT 741 ++ G P S+W+GR E H WGGS P Q+C CGL+ +C+D YCNCDA Q +W + Sbjct: 689 RPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTS 748 Query: 742 DKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPP 800 D +L+ +HLPVTQ+V+ DT + SEA + L PL C GD++ WN+ SF+T + L FP Sbjct: 749 DTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPA 808 Query: 801 IRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDEN 860 + DV F+F+T+ SGVF+EN+G ++R+EL +V F+FDVGNG Sbjct: 809 FHGELTADVCFFFKTTVSSGVFMENLG------ITDFIRIELRAPTEVTFSFDVGNGPCE 862 Query: 861 LTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSA 920 +TV S FND++WH VRAE NVK A L+VD P ++P P ++ ++ + L++G Sbjct: 863 VTVQSPT-PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT 921 Query: 921 ELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSY 980 ++R F+GC+R+++LNGV L+LE RA + G P C GHC+ C +GGRC E+ Sbjct: 922 ATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRG 981 Query: 981 YTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYI 1040 TCDC +A+DGP+C+++I +F G+ M Y+ Q + S + S Sbjct: 982 VTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSL---------- 1031 Query: 1041 PGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYV 1100 YR +T E ++ SF T+ +P++LLYV Sbjct: 1032 -------------------------------YRD--VTLTREMITLSFRTTRSPSLLLYV 1058 Query: 1101 SSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQ 1158 SSF +Y++V++ ++G+LQ+RY+L +P + + + DGQ H + I R + Sbjct: 1059 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINR--EEAVVM 1116 Query: 1159 VDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNV 1218 V+ +++ L ++ ++ K+L LG+V+E DP+ +R T GF+GCLS VRF Sbjct: 1117 VEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRA 1176 Query: 1219 APLKTHFRTPRP 1230 APLK R P Sbjct: 1177 APLKAALRPSGP 1188 >gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sapiens] Length = 1235 Score = 882 bits (2278), Expect = 0.0 Identities = 459/1238 (37%), Positives = 691/1238 (55%), Gaps = 114/1238 (9%) Query: 23 YGCDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKK 79 Y CD+ LV L S +SS S P FARL+ G GWSP + + WLQIDL ++ Sbjct: 4 YDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGER 63 Query: 80 HRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHF 139 + AVATQG + S +WVT Y+L++ D +W + Q F GN N +VV + L Sbjct: 64 MEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQP 123 Query: 140 HFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVF 199 AR++R +PL WNP+G+IG+R+ ++GC Y+++++ DG ++ YRF + + D+ Sbjct: 124 SIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDII 183 Query: 200 AFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLN 259 + FKT + DG+LLH EG GD++TL+L A L L ++ G + + ++ G +L+ Sbjct: 184 SLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLD 243 Query: 260 DQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHN 319 DQHWH V + R G+ VNFT+D + F G+F +NLD Sbjct: 244 DQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLD--------------------- 282 Query: 320 FRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPR 379 +EG V+F C P P+ F +++ +P F Sbjct: 283 ---------------------------YEGNVSFSCSQPQSMPVTFLSSRSYLALPDFSG 315 Query: 380 RGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRL 439 ++ +F+FRTW+ GLLLFS L G + L LS+G++ ++ Q G+ AG L Sbjct: 316 EEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVEL 375 Query: 440 NDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSN 499 NDG WH V+ A++NH +++D + + P I +G +Y+FGGCP + C S Sbjct: 376 NDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSP 435 Query: 500 QTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSW 559 F GCM L+ + G++V+L V+ LG ++++ D+CGI+DRC PN CEH G C QSW Sbjct: 436 LGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSW 495 Query: 560 DDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRE 619 F C C TGY+G TCH +Y++SCEAY+ G TSG + ID DGSGPL+PF++YC++ E Sbjct: 496 STFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMTE 555 Query: 620 NRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYN 679 AWT+++H+ TRV ++ E P+ G +Y AS E++ A N ++HCEQ + C Sbjct: 556 T-AWTIIQHNGSDLTRVRNTNPENPYAGFFEYV-ASMEQLQATINRAEHCEQEFTYYCKK 613 Query: 680 SRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQW 739 SRL+N G P S+W+GR E YWGGS P +Q+C CGL+ +C+D YCNCDAD+ +W Sbjct: 614 SRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEW 673 Query: 740 RTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRF 798 D GLL + +HLPVT++VI DT R SEA + L PL C GDR+ WN+ SF T A+ L F Sbjct: 674 TNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHF 733 Query: 799 PPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGD 858 P S DVSF+F+T+A SGVFLEN+G ++R+EL + V F+FDVGNG Sbjct: 734 PTFHGELSADVSFFFKTTASSGVFLENLG------IADFIRIELRSPTVVTFSFDVGNGP 787 Query: 859 ENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVG 918 ++V S FND++WH VR E N+K+A L+VD +P P ++ ++ + L+VG Sbjct: 788 FEISVQSPT-HFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVG 846 Query: 919 SAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERY 978 ++R F+GC+R+++LNG+TL+LE RA + P C GHC+ C +GG+C ER Sbjct: 847 GTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERP 906 Query: 979 SYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPG 1038 + CDC +A+ GP+C+++I +F G+ + YN Q Sbjct: 907 IGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQE----------------------N 944 Query: 1039 YIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLL 1098 Y+ ++ + +HG ++ E + FSF T+ P++LL Sbjct: 945 YLLSKNSSSHAASFHGD---------------------MKLSREMIKFSFRTTRTPSLLL 983 Query: 1099 YVSSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLF 1156 +VSSF ++Y++V+I +G+LQ+RY+L P V + + DGQ H I I R +F Sbjct: 984 FVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVF 1043 Query: 1157 IQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFN 1216 I++D ++ L ++ + K+L LGR++E +D + GF+GCLS V+ + Sbjct: 1044 IEID--DNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLS 1101 Query: 1217 NVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMP 1254 +VAPLK P + + V G ++ES+C A P Sbjct: 1102 HVAPLKAALHPSHP------DPVTVTGHVTESSCMAQP 1133 >gi|47519929 cell recognition molecule CASPR3 [Homo sapiens] Length = 1288 Score = 879 bits (2270), Expect = 0.0 Identities = 455/1212 (37%), Positives = 689/1212 (56%), Gaps = 60/1212 (4%) Query: 25 CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81 CD L L S +SS S P F+RL+ G GW+P + + WLQIDL ++ Sbjct: 31 CDAPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90 Query: 82 IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141 + AVATQG + S DWVT Y+L++ D +W + + F GN N +VV + L F Sbjct: 91 VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150 Query: 142 TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201 AR++R +PLAWNPRG+IG+R+ +YGC YK++++YFDG A+ YR + + + DV + Sbjct: 151 EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYRLDKKPLKPIRDVISL 210 Query: 202 SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261 FK + +G+LLH EG G+++TLEL L+ ++ G++ + T++ G +L+DQ Sbjct: 211 KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270 Query: 262 HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321 HWH V ++ VNFT+D + F GD L+L+ E+ GG+ R R +F Sbjct: 271 HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSYLDLNFEISFGGIPTPGRSRAFRRKSFH 330 Query: 322 GCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRG 381 GC+EN+ +N V++ +LA + +I G V+F C P P+ F +++ +PG Sbjct: 331 GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390 Query: 382 RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLND 441 +++V+F+FRTW+ G LLF L G G L L +G++ +S+ Q G+ AG LND Sbjct: 391 KVSVTFQFRTWNRAGHLLFGELRRGSGSFVLFLKDGKLKLSLFQPGQSPRNVTAGAGLND 450 Query: 442 GFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQT 501 G WH V+F A+ +H + +DD + V+ +LI +G +Y+FGGC +S C S Sbjct: 451 GQWHSVSFSAKWSHMNVVVDDDTAVQPLVA--VLIDSGDTYYFGGCLDNSSGSGCKSPLG 508 Query: 502 AFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDD 561 F GC+ L+ + + V+ LV+ LG + ++ D+CGITDRC P+ CEH G C QSWD Sbjct: 509 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 568 Query: 562 FICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRENR 621 F C C TGY GETCH+ LY++SCEA++ G SG + ID DGSGPL PF+VYC++ + Sbjct: 569 FSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTADA 628 Query: 622 AWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSR 681 AWTVV+H + G+ P + A ++ + N ++ CEQ + C +R Sbjct: 629 AWTVVQHGGPDAVTLRGAPSGHPRSAVSFAYAAGAGQLRSAVNLAERCEQRLALRCGTAR 688 Query: 682 LLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRT 741 ++ G P S+W+GR E H WGGS P Q+C CGL+ +C+D YCNCDA + +W + Sbjct: 689 RPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTS 748 Query: 742 DKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPP 800 D +L+ +HLPVTQ+V+ D R SEA + L PL C GD++ WN+ SF+T + L FP Sbjct: 749 DTIVLSQKEHLPVTQIVMTDAGRPHSEAAYTLGPLLCRGDQSFWNSASFNTETSYLHFPA 808 Query: 801 IRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDEN 860 + DV F+F+T+ SGVF+EN+G ++R+EL +V F+FDVGNG Sbjct: 809 FHGELTADVCFFFKTTVSSGVFMENLG------ITDFIRIELRAPTEVTFSFDVGNGPCE 862 Query: 861 LTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSA 920 +TV S FND++WH VRAE NVK A L+VD P ++P P ++ ++ + L++G Sbjct: 863 VTVQSPT-PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT 921 Query: 921 ELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSY 980 ++R F+GC+R+++LNGV L+LE RA + G P C GHC+ C +GGRC E+ Sbjct: 922 ATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRG 981 Query: 981 YTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYI 1040 TCDC +A+DGP+C+++I +F G+ M Y+ Q Y Sbjct: 982 VTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQE----------------------HYT 1019 Query: 1041 PGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYV 1100 ++ V H R V +T E ++ SF T+ P++LLYV Sbjct: 1020 LSENSSSLVSSLH-------------RDV--------TLTREMITLSFRTTRTPSLLLYV 1058 Query: 1101 SSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQ 1158 SSF +Y++V++ ++G+LQ+RY+L +P + + + DGQ H + I R + Sbjct: 1059 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINR--EEAVVM 1116 Query: 1159 VDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNV 1218 V+ T+++ L ++ ++ K+L LG+V+E DP+ +R T GF+GCLS VRF Sbjct: 1117 VEVNQSTKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRA 1176 Query: 1219 APLKTHFRTPRP 1230 APLK R P Sbjct: 1177 APLKAALRPSGP 1188 >gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2 [Homo sapiens] Length = 1207 Score = 708 bits (1827), Expect = 0.0 Identities = 354/897 (39%), Positives = 530/897 (59%), Gaps = 14/897 (1%) Query: 25 CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81 CD L L S +SS S P F+RL+ G GW+P + + WLQIDL ++ Sbjct: 31 CDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90 Query: 82 IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141 + AVATQG + S DWVT Y+L++ D +W + + F GN N +VV + L F Sbjct: 91 VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150 Query: 142 TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201 AR++R +PLAWNPRG+IG+R+ +YGC YK++++YFDG A+ Y + + + DV + Sbjct: 151 EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210 Query: 202 SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261 FK + +G+LLH EG G+++TLEL L+ ++ G++ + T++ G +L+DQ Sbjct: 211 KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270 Query: 262 HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321 HWH V ++ VNFT+D + F GD L+L+ E+ GG++ R R +F Sbjct: 271 HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFH 330 Query: 322 GCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRG 381 GC+EN+ +N V++ +LA + +I G V+F C P P+ F +++ +PG Sbjct: 331 GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390 Query: 382 RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLND 441 +++V+F+FRTW+ G LLF L G G L L +G++ +S+ Q+G+ AG LND Sbjct: 391 KVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLND 450 Query: 442 GFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQT 501 G WH V+F A+ +H + +DD + V+ +LI +G +Y+FGGC +S C S Sbjct: 451 GQWHSVSFSAKWSHMNVVVDDDTAVQPLVA--VLIDSGDTYYFGGCLGNSSGSGCKSPLG 508 Query: 502 AFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDD 561 F GC+ L+ + + V+ LV+ LG + ++ D+CGITDRC P+ CEH G C QSWD Sbjct: 509 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 568 Query: 562 FICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRENR 621 F C C TGY GETCH+ LY++SCEA++ G SG + ID DGSGPL PF+VYC++ ++ Sbjct: 569 FSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTDS- 627 Query: 622 AWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSR 681 AWTVVRH + G+ P + A ++ A N ++ CEQ + C +R Sbjct: 628 AWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGTAR 687 Query: 682 LLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRT 741 ++ G P S+W+GR E H WGGS P Q+C CGL+ +C+D YCNCDA Q +W + Sbjct: 688 RPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTS 747 Query: 742 DKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPP 800 D +L+ +HLPVTQ+V+ DT + SEA + L PL C GD++ WN+ SF+T + L FP Sbjct: 748 DTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPA 807 Query: 801 IRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDEN 860 + DV F+F+T+ SGVF+EN+G ++R+EL +V F+FDVGNG Sbjct: 808 FHGELTADVCFFFKTTVSSGVFMENLG------ITDFIRIELRAPTEVTFSFDVGNGPCE 861 Query: 861 LTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYV 917 +TV S FND++WH VRAE NVK A L+VD P ++P P ++ ++ + L++ Sbjct: 862 VTVQSPT-PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI 917 Score = 105 bits (261), Expect = 4e-22 Identities = 55/154 (35%), Positives = 94/154 (61%), Gaps = 4/154 (2%) Query: 1079 VTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGT--SPYVYQLTTR 1136 +T E ++ SF T+ +P++LLYVSSF +Y++V++ ++G+LQ+RY+L +P + + Sbjct: 956 LTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFK 1015 Query: 1137 PVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDP 1196 + DGQ H + I R + ++V+ +++ L ++ ++ K+L LG+V+E DP Sbjct: 1016 NMADGQLHQVKINREEAVVMVEVNQS--AKKQVILSSGTEFNAVKSLILGKVLEAAGADP 1073 Query: 1197 EIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRP 1230 + +R T GF+GCLS VRF APLK R P Sbjct: 1074 DTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGP 1107 Score = 35.8 bits (81), Expect = 0.29 Identities = 41/165 (24%), Positives = 58/165 (35%), Gaps = 27/165 (16%) Query: 852 FDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEY 911 F G N+T + ND +WH V + VD V PL + Sbjct: 433 FQAGQSPRNVTAGAG---LNDGQWHSVSFSAKWSHMNVVVDDDTAV---QPLVAVLIDSG 486 Query: 912 DQPLYVG-----SAELKRRP---FVGCLRAMRLNG-------VTLNLEGRANASEGTSPN 956 D + G S + P F GCLR + + V G + S Sbjct: 487 DTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCG 546 Query: 957 CTGHCAHPRLP--CFHGGRCVERYSYYTCDCDLTAFDGPYCNHDI 999 T C LP C HGG C + + ++CDC T + G C+ + Sbjct: 547 ITDRC----LPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSL 587 Score = 32.0 bits (71), Expect = 4.2 Identities = 35/128 (27%), Positives = 53/128 (41%), Gaps = 8/128 (6%) Query: 1084 VSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLR-YQLGTSPYVYQLTTRPVTDGQ 1142 V+F F T + LL+ VL DG L+L +Q G SP + DGQ Sbjct: 394 VTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG-LNDGQ 452 Query: 1143 PHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYN 1202 HS++ + + ++ + VD + ++L+DS LG +G P Sbjct: 453 WHSVSFSAKWSHMNVVVDDDTAVQPLVAVLIDSGDTYYFGGCLGNSSGSGCKSP------ 506 Query: 1203 TPGFSGCL 1210 GF GCL Sbjct: 507 LGGFQGCL 514 >gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3 [Homo sapiens] Length = 944 Score = 344 bits (882), Expect = 4e-94 Identities = 184/512 (35%), Positives = 286/512 (55%), Gaps = 56/512 (10%) Query: 688 GYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRTDKGLLT 747 G P S+W+GR E H WGGS P Q+C CGL+ +C+D YCNCDA + +W +D +L+ Sbjct: 428 GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLS 487 Query: 748 FVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPPIRANHS 806 +HLPVTQ+V+ D + SEA + L PL C GD++ WN+ SF+T + L FP + Sbjct: 488 QKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELT 547 Query: 807 LDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDENLTVHSD 866 DV F+F+T+ SGVF+EN+G ++R+EL +V F+FDVGNG +TV S Sbjct: 548 ADVCFFFKTTVSSGVFMENLG------ITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSP 601 Query: 867 DFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSAELKRRP 926 FND++WH VRAE NVK A L+VD P ++P P ++ ++ + L++G ++R Sbjct: 602 T-PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG 660 Query: 927 FVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSYYTCDCD 986 F+GC+R+++LNGV L+LE RA G P C GHC+ C +GGRC E+ TCDC Sbjct: 661 FLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCA 720 Query: 987 LTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYIPGYDTP 1046 +A+DGP+C+++I +F G+ M Y+ Q Y ++ Sbjct: 721 FSAYDGPFCSNEISAYFATGSSMTYHFQE----------------------HYTLSENSS 758 Query: 1047 GYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVSSFVRD 1106 V H R V +T E ++ SF T+ P++LLYVSSF + Sbjct: 759 SLVSSLH-------------RDV--------TLTREMITLSFRTTRTPSLLLYVSSFYEE 797 Query: 1107 YMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQVDYFPL 1164 Y++V++ ++G+LQ+RY+L +P + + + DGQ H + I R + V+ Sbjct: 798 YLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINR--EEAVVMVEVNQS 855 Query: 1165 TEQKFSLLVDSQLDSPKALYLGRVM-ETGVID 1195 +++ L ++ ++ K+L LG+V+ +G +D Sbjct: 856 AKKQVILSSGTEFNAVKSLILGKVLGRSGPVD 887 Score = 142 bits (359), Expect = 2e-33 Identities = 65/136 (47%), Positives = 87/136 (63%) Query: 487 CPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSP 546 C +S C S F GC+ L+ + + V+ LV+ LG + ++ D+CGITDRC P Sbjct: 187 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 246 Query: 547 NMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSG 606 + CEH G C QSWD F C C TGY GETCH+ LY++SCEA++ G SG + ID DGSG Sbjct: 247 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306 Query: 607 PLKPFVVYCDIRENRA 622 PL PF+VYC++ + A Sbjct: 307 PLGPFLVYCNMTDRSA 322 Score = 46.2 bits (108), Expect = 2e-04 Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 16/135 (11%) Query: 201 FSFKTEEKDGLLLHAEGAQGDYVTLELEG-AHLLLHMSLGSSPIQPRPGHTTVSAGGVLN 259 F FKT G+ + G D++ +EL + +G+ P + TV + N Sbjct: 552 FFFKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCE-----VTVQSPTPFN 605 Query: 260 DQHWHYVRVDRFGRDVNFTLDGYVQRF--ILNGDFERLNLDTEMFIGGLVGAARKNLAYR 317 D WH+VR +R + + +D Q+ RL L++++FIGG R Sbjct: 606 DNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR------ 659 Query: 318 HNFRGCIENVIFNRV 332 F GCI ++ N V Sbjct: 660 -GFLGCIRSLQLNGV 673 Score = 35.4 bits (80), Expect = 0.38 Identities = 46/222 (20%), Positives = 80/222 (36%), Gaps = 30/222 (13%) Query: 364 NFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSI 423 +F +++ P F V F F+T +G+ + + LG + E + + Sbjct: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFM-----ENLGITDFIRIELRAPTEV 583 Query: 424 AQS-----GRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDV--EGAEVRVSYPLLI 476 S G ++ + ND WH V A + +D + + + + Sbjct: 584 TFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRL 643 Query: 477 RTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFD 536 + + F GG + Q F GC+ L+++G V L L E + E Sbjct: 644 QLNSQLFIGGTA---------TRQRGFLGCIRSLQLNG--VALDLEERATVMPGVEP--- 689 Query: 537 TCGITDRCSP--NMCEHDGRCYQSWDDFICYCELTGYKGETC 576 G CS ++C + GRC + C C + Y G C Sbjct: 690 --GCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFC 729 Score = 33.5 bits (75), Expect = 1.5 Identities = 11/32 (34%), Positives = 18/32 (56%) Query: 968 CFHGGRCVERYSYYTCDCDLTAFDGPYCNHDI 999 C HGG C + + ++CDC T + G C+ + Sbjct: 249 CEHGGECSQSWDTFSCDCLGTGYTGETCHSSL 280 Score = 32.7 bits (73), Expect = 2.5 Identities = 31/138 (22%), Positives = 55/138 (39%), Gaps = 13/138 (9%) Query: 1083 EVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGTSPY-VYQLTTRPVTDG 1141 +V F F T+ + V + + + D++ + ++ + + +G P V + P D Sbjct: 549 DVCFFFKTTVSSGVFME-NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDN 607 Query: 1142 QPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRY 1201 Q H + R + +QVD P Q +L L++G QR Sbjct: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATR-------QR- 659 Query: 1202 NTPGFSGCLSGVRFNNVA 1219 GF GC+ ++ N VA Sbjct: 660 ---GFLGCIRSLQLNGVA 674 >gi|239743729 PREDICTED: similar to contactin associated protein-like 3B [Homo sapiens] Length = 380 Score = 246 bits (628), Expect = 1e-64 Identities = 121/324 (37%), Positives = 188/324 (58%), Gaps = 3/324 (0%) Query: 25 CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81 CD L L S +SS S P F+RL+ G GW+P + + WLQIDL ++ Sbjct: 31 CDAPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90 Query: 82 IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141 + AVATQG + S DWVT Y+L++ D +W + + F GN N +VV + L F Sbjct: 91 VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150 Query: 142 TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201 AR++R +PLAWNPRG+IG+R+ +YGC YK++++YFDG A+ Y + + + DV + Sbjct: 151 EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210 Query: 202 SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261 FK + +G+LLH EG G+++TLEL L+ ++ G++ + T++ G +L+DQ Sbjct: 211 KFKAMQSNGILLHREGQHGNHITLELIKRKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270 Query: 262 HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321 HWH V ++ VNFT+D + F GD L+L+ E+ GG+ R R +F Sbjct: 271 HWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGIPTPGRSRAFTRKSFH 330 Query: 322 GCIENVIFNRVNIADLAVRRHSRI 345 GC+EN+ +N V++ +LA + +I Sbjct: 331 GCLENLYYNGVDVTELAKKHKPQI 354 Score = 33.1 bits (74), Expect = 1.9 Identities = 35/140 (25%), Positives = 51/140 (36%), Gaps = 11/140 (7%) Query: 382 RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQ-------FA 434 R +S +F+ G+LL R G H+ L L + ++ V SG KL Sbjct: 205 RDVISLKFKAMQSNGILLH-REGQHGNHITLELIKRKL-VFFLNSGNAKLPSTIAPVTLT 262 Query: 435 AGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRW 494 G L+D WH V ++D + FGG P P Sbjct: 263 LGSLLDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGIPTPGR-- 320 Query: 495 DCHSNQTAFHGCMELLKVDG 514 + +FHGC+E L +G Sbjct: 321 SRAFTRKSFHGCLENLYYNG 340 >gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens] Length = 1477 Score = 134 bits (336), Expect = 8e-31 Identities = 119/451 (26%), Positives = 191/451 (42%), Gaps = 69/451 (15%) Query: 174 ILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLL 233 I F G + Y + +S D SFKT +++GL+LH G DYV L L+ + Sbjct: 283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHT-GKSADYVNLALKNGAVS 341 Query: 234 LHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGR--------------DVNFTL 279 L ++LGS + G ND WH V+V R R D T Sbjct: 342 LVINLGSGAFEA----LVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTT 397 Query: 280 DGYVQRFILNGDFERLNLDTEMFIGGLVGAAR-KNLAYRHNFRGCIENVIFN----RVNI 334 GY Q D+ L D ++GG A +NF GC++ V++ R+ + Sbjct: 398 TGYTQE-----DYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLEL 452 Query: 335 ADLAVRRHSRITFEGKVAFRCLDPVP-HPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWD 393 + LA + ++ G VAF+C + PI F P +F+ +P + + ++SF FRT + Sbjct: 453 SRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTE 512 Query: 394 LTGLLLFS----RLGDGLGHVE--------LTLSEGQVNVSIAQ-SGRKKLQFAAGYRLN 440 GL+LFS R H + + + +G + + + SG K++ A ++N Sbjct: 513 PNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIK-ALLKKVN 571 Query: 441 DGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPK-------PASR 493 DG W+ V+F IS++ + ++ + GG P+ P Sbjct: 572 DGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEV 631 Query: 494 WDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCS-------- 545 W N + GC+ L +DGQ ++ + AEV T G+ CS Sbjct: 632 WTALLNY-GYVGCIRDLFIDGQSKDIRQM--------AEVQ-STAGVKPSCSKETAKPCL 681 Query: 546 PNMCEHDGRCYQSWDDFICYCELTGYKGETC 576 N C+++G C W+ ++C C TGY G +C Sbjct: 682 SNPCKNNGMCRDGWNRYVCDCSGTGYLGRSC 712 Score = 107 bits (267), Expect = 8e-23 Identities = 106/425 (24%), Positives = 184/425 (43%), Gaps = 27/425 (6%) Query: 168 CPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG-DYVTLE 226 C +A +L +DG + + P + DV + F+++ G+L+ D + LE Sbjct: 712 CEREATVLSYDGSMFMKIQLPVVMHTEAEDV-SLRFRSQRAYGILMATTSRDSADTLRLE 770 Query: 227 LEGAHLLLHMSLGSSPIQ--PRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGY-V 283 L+ + L ++L I G T+ AG LND WH VRV R G+ + T+D Sbjct: 771 LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 830 Query: 284 QRFILNGDFERL---NLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVR 340 + GD RL N++T G++ R + NF G ++++ FN + DL Sbjct: 831 MTGQMAGDHTRLEFHNIET-----GIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLC-- 883 Query: 341 RHSRITF-EGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLL 399 ++ I + E F + + P+ F ++V + + + F+F+T L GL+L Sbjct: 884 KNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLIL 943 Query: 400 FSRLGDGLGHVELTLSEGQVN-VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQ-ENHAV 457 ++ GDG + + L +G ++ V +G ++ ++ LND WH V N Sbjct: 944 YNS-GDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT 1002 Query: 458 ISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWD---CHSNQTAFHGCMELLKVDG 514 + ID ++ L Y GG K + H+ + F GC+ + ++G Sbjct: 1003 VKIDTKITTQITAGARNLDLKSDLYI-GGVAKETYKSLPKLVHAKE-GFQGCLASVDLNG 1060 Query: 515 QLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGE 574 +L +L L ++ G + C + C + G C Q WD F C C +T + G Sbjct: 1061 RLPDLI---SDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGP 1117 Query: 575 TCHTP 579 C+ P Sbjct: 1118 LCNDP 1122 Score = 82.0 bits (201), Expect = 4e-15 Identities = 119/527 (22%), Positives = 204/527 (38%), Gaps = 130/527 (24%) Query: 760 GDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPS 819 GD + A+F R + D ++ T S + A ++A S+ + F F+T++ Sbjct: 886 GDIDYCELNARFGFRNI--IADPVTFKTKSSYVALAT----LQAYTSMHLFFQFKTTSLD 939 Query: 820 GVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVR 879 G+ L N G ++ VEL + + FD+GNG NL S + ND++WH V Sbjct: 940 GLILYNSGDG-----NDFIVVEL-VKGYLHYVFDLGNG-ANLIKGSSNKPLNDNQWHNVM 992 Query: 880 AEINVKQAR-LRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSAELK-----------RRPF 927 + +++D + + ++ LY+G + + F Sbjct: 993 ISRDTSNLHTVKIDTKITTQITAGARN---LDLKSDLYIGGVAKETYKSLPKLVHAKEGF 1049 Query: 928 VGCLRAMRLNGVTLNLEGRA--------NASEGTSPNCTGHCAHPRLPCFHGGRCVERYS 979 GCL ++ LNG +L A EG S C C + G C++++ Sbjct: 1050 QGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDS------CSNQGVCLQQWD 1103 Query: 980 YYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGY 1039 ++CDC +T+F GP CN +PGT +++ S+ Sbjct: 1104 GFSCDCSMTSFSGPLCN-------DPGT-----------------TYIFSK--------- 1130 Query: 1040 IPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLY 1099 G G +P RP + + ++ FST AVL+ Sbjct: 1131 --------------GGGQITYKWPPNDRP---------STRADRLAIGFSTVQKEAVLVR 1167 Query: 1100 V--SSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSINITRVYRNLFI 1157 V SS + DY+ + I G + +++ +GT + + + DG+ H + TR N + Sbjct: 1168 VDSSSGLGDYLELHI-HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATL 1226 Query: 1158 QVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNN 1217 QVD +P+ E + + + L + T +I + Q F G LSG+ +N Sbjct: 1227 QVDSWPVIE---------RYPAGRQLTIFNSQATIIIGGKEQ---GQPFQGQLSGLYYNG 1274 Query: 1218 VAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEVPPEL 1264 + L M AE + + G + RLV EVP + Sbjct: 1275 LKVLN--------MAAENDANIAIVGNV---------RLVGEVPSSM 1304 Score = 61.2 bits (147), Expect = 7e-09 Identities = 61/268 (22%), Positives = 118/268 (44%), Gaps = 36/268 (13%) Query: 788 ISFHTGAA-LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPY---VRVELN 843 I+F T + + P A + +SF FRT+ P+G+ L + G P Q + ++V+ Sbjct: 482 ITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFF 541 Query: 844 TSR----DVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVD--HRPWV 897 + D+G+G + + + + ND EW+ V + + + + V+ P+ Sbjct: 542 AIEMLDGHLYLLLDMGSG--TIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYT 599 Query: 898 LRPMPLQTYIWMEYDQPLYVGS---------------AELKRRPFVGCLRAMRLNGVTLN 942 P ++ I ++ D LY+G L +VGC+R + ++G + + Sbjct: 600 A---PGESEI-LDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKD 655 Query: 943 LEGRAN--ASEGTSPNCTGHCAHPRL--PCFHGGRCVERYSYYTCDCDLTAFDGPYCNHD 998 + A ++ G P+C+ A P L PC + G C + ++ Y CDC T + G C + Sbjct: 656 IRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCERE 715 Query: 999 IGGF-FEPGTWMRYNLQSALRSAAREFS 1025 ++ +M+ L + + A + S Sbjct: 716 ATVLSYDGSMFMKIQLPVVMHTEAEDVS 743 Score = 48.1 bits (113), Expect = 6e-05 Identities = 41/193 (21%), Positives = 82/193 (42%), Gaps = 25/193 (12%) Query: 175 LYFDGDDAISYRFP---RGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG--DYVTLELEG 229 ++ G I+Y++P R +R+ D A F T +K+ +L+ + + G DY+ L + Sbjct: 1127 IFSKGGGQITYKWPPNDRPSTRA--DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQ 1184 Query: 230 AHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGY--VQRFI 287 + + ++G+ I + ++ND +H VR R G + +D + ++R+ Sbjct: 1185 GKIGVKFNVGTDDI------AIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYP 1238 Query: 288 LNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITF 347 N + IGG F+G + + +N + + ++A + I Sbjct: 1239 AGRQLTIFNSQATIIIGG--------KEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAI 1290 Query: 348 EGKVAFRCLDPVP 360 G V R + VP Sbjct: 1291 VGNV--RLVGEVP 1301 Score = 46.2 bits (108), Expect = 2e-04 Identities = 101/477 (21%), Positives = 170/477 (35%), Gaps = 87/477 (18%) Query: 776 LRCYGDRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRR 835 L C+ + S G RFP A ++SF +T + G+ L +C Sbjct: 21 LGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCD--- 77 Query: 836 PYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDH-- 893 ++ + L + +F + + + D ND WH VR + L +D Sbjct: 78 -FLELILTRGGRLQLSFSIFCAEPATLLA--DTPVNDGAWHSVRIRRQFRNTTLFIDQVE 134 Query: 894 RPWV-----LRPMPLQTYIWMEYDQPLYVGSAELK--------RRPFVGCLRAMRLNGVT 940 WV R M + + +++ P + +A LK R PF G +R +R+N Sbjct: 135 AKWVEVKSKRRDMTVFSGLFVG-GLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQ 193 Query: 941 L--------NLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDG 992 + L+ S G SP G + C +GG C CDC T F G Sbjct: 194 VLPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGV-CLNGGVCSVVDDQAVCDCSRTGFRG 252 Query: 993 PYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYIPGYDTPGYVPGY 1052 C+ + + +H++ + G G + Y+ + Sbjct: 253 KDCSQE-------------------DNNVEGLAHLMMG-----DQGKSKGKEE--YIATF 286 Query: 1053 HGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLI 1112 G Y D + P+ + + +E++ SF T ++L+ DY+ + + Sbjct: 287 KGSEYFCYDLS---------QNPIQS-SSDEITLSFKTLQRNGLMLHTGKSA-DYVNLAL 335 Query: 1113 KDDGTLQLRYQLGTSPYVYQLTTRPV----TDGQPHSINITRVYRN--------LFIQVD 1160 K +G + L LG+ ++ PV D H + +TR R + I VD Sbjct: 336 K-NGAVSLVINLGSG--AFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVD 392 Query: 1161 YFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNN 1217 LT ++ + L S Y+G T + N F GCL V + N Sbjct: 393 GI-LTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNN---FMGCLKEVVYKN 445 Score = 42.7 bits (99), Expect = 0.002 Identities = 52/214 (24%), Positives = 78/214 (36%), Gaps = 34/214 (15%) Query: 385 VSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEG-QVNVSIAQSGRKKLQFAAGYRLNDGF 443 +SF+ +T GL+L+ +EL L+ G ++ +S + + A +NDG Sbjct: 54 MSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGA 113 Query: 444 WHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTS-YFFGGCP-------------- 488 WH V Q + + ID VE V V T S F GG P Sbjct: 114 WHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLAS 173 Query: 489 ----KPASRW--DCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITD 542 +P W D N + ++L VD V L G C + Sbjct: 174 VREREPFKGWIRDVRVNSS------QVLPVDSGEVKLDDEPPNSGG------GSPCEAGE 221 Query: 543 RCSPNMCEHDGRCYQSWDDFICYCELTGYKGETC 576 +C + G C D +C C TG++G+ C Sbjct: 222 EGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDC 255 Score = 34.7 bits (78), Expect = 0.65 Identities = 45/168 (26%), Positives = 73/168 (43%), Gaps = 20/168 (11%) Query: 175 LYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLEL---EGAH 231 L F G + RFP+ + +F KT GL+L+ + +G LEL G Sbjct: 31 LEFPGAEGQWTRFPKW-NACCESEMSFQLKTRSARGLVLYFDD-EGFCDFLELILTRGGR 88 Query: 232 LLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFI-LNG 290 L L S+ + +P T+ A +ND WH VR+ R R+ +D +++ + Sbjct: 89 LQLSFSIFCA--EP----ATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKS 142 Query: 291 DFERLNLDTEMFIGGL-----VGAARKNLA---YRHNFRGCIENVIFN 330 + + + +F+GGL A + LA R F+G I +V N Sbjct: 143 KRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVN 190 Score = 32.7 bits (73), Expect = 2.5 Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 7/101 (6%) Query: 796 LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYV---RVELNTSRDVV-FA 851 ++ P + + DVS FR+ G+ + R + RV+L + D + Sbjct: 729 IQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRIN 788 Query: 852 FDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVD 892 + G E L + ND+EWH VR K +L VD Sbjct: 789 CNSSKGPETLFA---GYNLNDNEWHTVRVVRRGKSLKLTVD 826 Score = 31.2 bits (69), Expect = 7.2 Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 25/169 (14%) Query: 800 PIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDE 859 PI+++ S +++ F+T +G+ L YV + L V ++G+G Sbjct: 300 PIQSS-SDEITLSFKTLQRNGLMLHTGKSA------DYVNLALKNGA-VSLVINLGSGAF 351 Query: 860 NLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQT--------YIWMEY 911 V + +FND+ WH V+ N++Q + H + + T Y + Sbjct: 352 EALVEPVNGKFNDNAWHDVKVTRNLRQ-HSGIGHAMVTISVDGILTTTGYTQEDYTMLGS 410 Query: 912 DQPLYVG----SAELKRRP----FVGCLRAMRLNGVTLNLEGRANASEG 952 D YVG +A+L P F+GCL+ + + LE A +G Sbjct: 411 DDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQG 459 >gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens] Length = 1642 Score = 133 bits (335), Expect = 1e-30 Identities = 118/442 (26%), Positives = 190/442 (42%), Gaps = 56/442 (12%) Query: 177 FDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHM 236 F G++ Y +S D +F+T +++GL+LH G DYV L L+ + L + Sbjct: 268 FKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHT-GKSADYVNLSLKSGAVWLVI 326 Query: 237 SLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGR--------------DVNFTLDGY 282 +LGS + G ND WH VRV R R D T GY Sbjct: 327 NLGSGAFEA----LVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTTTGY 382 Query: 283 VQRFILNGDFERLNLDTEMFIGGLVGAAR-KNLAYRHNFRGCIENVIFN----RVNIADL 337 Q D+ L D +IGG A +NF GC+++V++ ++ ++ L Sbjct: 383 TQE-----DYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRL 437 Query: 338 AVRRHSRITFEGKVAFRCLDPVP-HPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTG 396 A ++ +G ++FRC D P+ F P FV +P + + ++S FRT + G Sbjct: 438 AKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNG 497 Query: 397 LLLFS---RLGDGLG---------HVELTLSEGQVNVSIAQ-SGRKKLQFAAGYRLNDGF 443 LLLFS R G G G + + L +G + + + SG KL+ A+ ++NDG Sbjct: 498 LLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLR-ASSRKVNDGE 556 Query: 444 WHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPK--------PASRWD 495 W V+F IS++ + ++ + + GG P+ P W Sbjct: 557 WCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWT 616 Query: 496 CHSNQTAFHGCMELLKVDGQLVNLT-LVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGR 554 + + + GC+ L +DG+ +L L E + G F + +C+ C + G Sbjct: 617 A-ALRAGYVGCVRDLFIDGRSRDLRGLAEAQ--GAVGVAPFCSRETLKQCASAPCRNGGV 673 Query: 555 CYQSWDDFICYCELTGYKGETC 576 C + W+ FIC C TG+ G C Sbjct: 674 CREGWNRFICDCIGTGFLGRVC 695 Score = 112 bits (279), Expect = 3e-24 Identities = 110/427 (25%), Positives = 183/427 (42%), Gaps = 41/427 (9%) Query: 168 CPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG-DYVTLE 226 C +A +L +DG + P + DV + F ++ GL++ + D + LE Sbjct: 695 CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 753 Query: 227 LEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRF 286 L+G + L ++LG P T+ AG LND WH VRV R G+ + ++D Sbjct: 754 LDGGQMKLTVNLGKGP-------ETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEG 806 Query: 287 ILNGDFERL---NLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHS 343 + G RL N++T G++ R NF G + ++FN D + Sbjct: 807 QMAGAHMRLEFHNIET-----GIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQC--KDG 859 Query: 344 RITF-EGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSR 402 IT+ E F V P+ F +++ + + + F+F+T GLLLF+ Sbjct: 860 DITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNS 919 Query: 403 LGDGLGHVELTLSEGQVN-VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQE--NHAVIS 459 G+G + + L +G ++ V +G ++ + +ND WH V V+++ N + Sbjct: 920 -GNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNV-VVSRDPGNVHTLK 977 Query: 460 IDD------VEGAE-VRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKV 512 ID GA + + L I + F PK + D F GC+ + + Sbjct: 978 IDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRD------GFQGCLASVDL 1031 Query: 513 DGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYK 572 +G+L +L R+G +V G + C+ C + G C Q WD F C C +T Y Sbjct: 1032 NGRLPDLIADALHRIG---QVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYG 1088 Query: 573 GETCHTP 579 G C+ P Sbjct: 1089 GPVCNDP 1095 Score = 89.7 bits (221), Expect = 2e-17 Identities = 116/491 (23%), Positives = 188/491 (38%), Gaps = 124/491 (25%) Query: 796 LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVG 855 L ++A S+ + F F+T+AP G+ L N G ++ +EL + + FD+G Sbjct: 889 LALATLQAYASMHLFFQFKTTAPDGLLLFNSGNG-----NDFIVIEL-VKGYIHYVFDLG 942 Query: 856 NGDENLTVHSDDFEFNDDEWHLVRAEINVKQAR-LRVDHRPWVLRPMPLQTYIWMEYDQP 914 NG + +SD ND++WH V + L++D R + ++ Sbjct: 943 NGPSLMKGNSDK-PVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARN---LDLKGE 998 Query: 915 LYVGSAE-----------LKRRPFVGCLRAMRLNGVTLNLEGRA--------NASEGTSP 955 LY+G R F GCL ++ LNG +L A +G S Sbjct: 999 LYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPST 1058 Query: 956 NCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQS 1015 CT C + G C++++ +TCDC +T++ GP CN +PGT + Sbjct: 1059 TCTEES------CANQGVCLQQWDGFTCDCTMTSYGGPVCN-------DPGTTYIFGKGG 1105 Query: 1016 ALRSAAREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGP 1075 AL + Y P RP + Sbjct: 1106 ALIT-------------------------------------YTWPPNDRPSTRM------ 1122 Query: 1076 VYNVTGEEVSFSFSTSSAPAVLLYV--SSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQL 1133 + ++ FST AVL+ V +S + DY+ + I D GT+ + + +GT Sbjct: 1123 ------DRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-DQGTVGVIFNVGTDDITIDE 1175 Query: 1134 TTRPVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGV 1193 V+DG+ H + TR N +QVD +P+ E+ + + +S A+ +G Sbjct: 1176 PNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGRQLTIFNSQAAIKIG------- 1228 Query: 1194 IDPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAM 1253 R F G +SG+ +N + L + AE +R +G L Sbjct: 1229 -----GRDQGRPFQGQVSGLYYNGLKVL--------ALAAESDPNVRTEGHL-------- 1267 Query: 1254 PRLVSEVPPEL 1264 RLV E P L Sbjct: 1268 -RLVGEGPSVL 1277 Score = 79.3 bits (194), Expect = 2e-14 Identities = 160/712 (22%), Positives = 271/712 (38%), Gaps = 109/712 (15%) Query: 385 VSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLNDGFW 444 +SF RT LLL+ G +EL L +G++ + S + + D W Sbjct: 53 LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRW 112 Query: 445 HEVNFVAQENHAVISID-DVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTA- 502 H V +++D + AEVR S ++ + F GG P P R + T Sbjct: 113 HMVLLTRDARRTALAVDGEARAAEVR-SKRREMQVASDLFVGGIP-PDVRLSALTLSTVK 170 Query: 503 ----FHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSP--NMCEHDGRC- 555 F G + LK+ + L +G R G A+ L C+P N C + G C Sbjct: 171 YEPPFRGLLANLKLGERPPALLGSQGLR-GATADPL---------CAPARNPCANGGLCT 220 Query: 556 YQSWDDFICYCELTGYKGETC-----------HTPLYKESCEAYRLSGKTSGNFTID--- 601 + + C C TG+ G+ C H L E E + + K + F D Sbjct: 221 VLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVATFKGNEFFCYDLSH 280 Query: 602 -PDGSGPLKPFVVYCDIRENRAWT-----------VVRHDRLWTTRVTGSSMERPFLGAI 649 P S + + + ++ N ++ +W GS + + Sbjct: 281 NPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEALVEPV 340 Query: 650 --QYWNASWEEVSALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGG 707 ++ + +W +V N QH + + T GY + + FY GG Sbjct: 341 NGKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYIGG 400 Query: 708 SQPGIQRCACGLDRS---CVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNR 764 S + + C+ +Y N D R K GD Sbjct: 401 SPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKE---------------GDPKM 445 Query: 765 STSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPPIRANHSLDVSFYFRTSAPSGVFL 823 F RC D + + ++F + A + P A + +S FRT+ P+G+ L Sbjct: 446 KLQGDLSF----RCE-DVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLL 500 Query: 824 ENMG-------GPYCQWRRP-YVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEW 875 + G G + +R Y +EL + D+G+G L S + ND EW Sbjct: 501 FSQGRRAGGGAGSHSSAQRADYFAMELLDGH-LYLLLDMGSGGIKLRASSR--KVNDGEW 557 Query: 876 HLVRAEINVKQARLRVDHR--PWVLRP----MPLQTYIWM-------EYDQPL--YVGSA 920 V + + ++ + V+ R P++ + L++ +++ D PL V +A Sbjct: 558 CHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTA 617 Query: 921 ELKRRPFVGCLRAMRLNGVTLNLEGRANA--SEGTSPNCTGH----CAHPRLPCFHGGRC 974 L R +VGC+R + ++G + +L G A A + G +P C+ CA PC +GG C Sbjct: 618 AL-RAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASA--PCRNGGVC 674 Query: 975 VERYSYYTCDCDLTAFDGPYCNHDIGGF-FEPGTWMRYNLQSALRSAAREFS 1025 E ++ + CDC T F G C + ++ +M+ L +A+ + A + S Sbjct: 675 REGWNRFICDCIGTGFLGRVCEREATVLSYDGSMYMKIMLPNAMHTEAEDVS 726 Score = 48.5 bits (114), Expect = 4e-05 Identities = 89/410 (21%), Positives = 142/410 (34%), Gaps = 82/410 (20%) Query: 153 WNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLL 212 W P L L L +AD L F G R+ R + +FS +T LL Sbjct: 7 WRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTNATRALL 66 Query: 213 LHAE-GAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRF 271 L+ + G D++ L L L L +L + +P T+ + D WH V + R Sbjct: 67 LYLDDGGDCDFLELLLVDGRLRLRFTLSCA--EP----ATLQLDTPVADDRWHMVLLTRD 120 Query: 272 GRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAAR------KNLAYRHNFRGCIE 325 R +DG + + + + +++F+GG+ R + Y FRG + Sbjct: 121 ARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLA 180 Query: 326 NVIFN------------RVNIAD--LAVRRH--------------------SRITFEGKV 351 N+ R AD A R+ S F GK Sbjct: 181 NLKLGERPPALLGSQGLRGATADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKF 240 Query: 352 AFRCLDPVPHP----INFGGPHNFVQV--------------PGFPRRGRLAVSFRFRTWD 393 P+ P +N G FV P + ++FR T Sbjct: 241 CSEEEHPMEGPAHLTLNSEGKEEFVATFKGNEFFCYDLSHNPIQSSTDEITLAFR--TLQ 298 Query: 394 LTGLLLFSRLGDGLGHVELTLSEGQV--NVSIAQSGRKKLQFAAGYRLNDGFWHEVNFV- 450 GL+L + G +V L+L G V +++ + L + ND WH+V Sbjct: 299 RNGLMLHT--GKSADYVNLSLKSGAVWLVINLGSGAFEALVEPVNGKFNDNAWHDVRVTR 356 Query: 451 -----AQENHAVISIDDVEGAEVRVSYP----LLIRTGTSYFFGGCPKPA 491 A HA+++I V+G Y ++ + ++ GG P A Sbjct: 357 NLRQHAGIGHAMVTI-SVDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTA 405 Score = 40.4 bits (93), Expect = 0.012 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 2/79 (2%) Query: 1083 EVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLG-TSPYVYQLTTRPVTDG 1141 E+SFS T++ A+LLY+ L+ DG L+LR+ L P QL T PV D Sbjct: 52 ELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDT-PVADD 110 Query: 1142 QPHSINITRVYRNLFIQVD 1160 + H + +TR R + VD Sbjct: 111 RWHMVLLTRDARRTALAVD 129 >gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens] Length = 1547 Score = 131 bits (329), Expect = 5e-30 Identities = 119/458 (25%), Positives = 191/458 (41%), Gaps = 76/458 (16%) Query: 174 ILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLL 233 I F G + Y + +S D SFKT +++GL+LH G DYV L L+ + Sbjct: 316 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHT-GKSADYVNLALKNGAVS 374 Query: 234 LHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGR-------------------- 273 L ++LGS + G ND WH V+V R R Sbjct: 375 LVINLGSGAFEA----LVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTIS 430 Query: 274 -DVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAAR-KNLAYRHNFRGCIENVIFN- 330 D T GY Q D+ L D ++GG A +NF GC++ V++ Sbjct: 431 VDGILTTTGYTQE-----DYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKN 485 Query: 331 ---RVNIADLAVRRHSRITFEGKVAFRCLDPVP-HPINFGGPHNFVQVPGFPRRGRLAVS 386 R+ ++ LA + ++ G VAF+C + PI F P +F+ +P + + ++S Sbjct: 486 NDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSIS 545 Query: 387 FRFRTWDLTGLLLFS----RLGDGLGHVE--------LTLSEGQVNVSIAQ-SGRKKLQF 433 F FRT + GL+LFS R H + + + +G + + + SG K++ Sbjct: 546 FDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIK- 604 Query: 434 AAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPK---- 489 A ++NDG W+ V+F IS++ + ++ + GG P+ Sbjct: 605 ALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAG 664 Query: 490 ---PASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCS- 545 P W N + GC+ L +DGQ ++ + AEV T G+ CS Sbjct: 665 LVFPTEVWTALLNY-GYVGCIRDLFIDGQSKDIRQM--------AEVQ-STAGVKPSCSK 714 Query: 546 -------PNMCEHDGRCYQSWDDFICYCELTGYKGETC 576 N C+++G C W+ ++C C TGY G +C Sbjct: 715 ETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSC 752 Score = 107 bits (267), Expect = 8e-23 Identities = 106/425 (24%), Positives = 184/425 (43%), Gaps = 27/425 (6%) Query: 168 CPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG-DYVTLE 226 C +A +L +DG + + P + DV + F+++ G+L+ D + LE Sbjct: 752 CEREATVLSYDGSMFMKIQLPVVMHTEAEDV-SLRFRSQRAYGILMATTSRDSADTLRLE 810 Query: 227 LEGAHLLLHMSLGSSPIQ--PRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGY-V 283 L+ + L ++L I G T+ AG LND WH VRV R G+ + T+D Sbjct: 811 LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 870 Query: 284 QRFILNGDFERL---NLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVR 340 + GD RL N++T G++ R + NF G ++++ FN + DL Sbjct: 871 MTGQMAGDHTRLEFHNIET-----GIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLC-- 923 Query: 341 RHSRITF-EGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLL 399 ++ I + E F + + P+ F ++V + + + F+F+T L GL+L Sbjct: 924 KNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLIL 983 Query: 400 FSRLGDGLGHVELTLSEGQVN-VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQ-ENHAV 457 ++ GDG + + L +G ++ V +G ++ ++ LND WH V N Sbjct: 984 YNS-GDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT 1042 Query: 458 ISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWD---CHSNQTAFHGCMELLKVDG 514 + ID ++ L Y GG K + H+ + F GC+ + ++G Sbjct: 1043 VKIDTKITTQITAGARNLDLKSDLYI-GGVAKETYKSLPKLVHAKE-GFQGCLASVDLNG 1100 Query: 515 QLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGE 574 +L +L L ++ G + C + C + G C Q WD F C C +T + G Sbjct: 1101 RLPDLI---SDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGP 1157 Query: 575 TCHTP 579 C+ P Sbjct: 1158 LCNDP 1162 Score = 84.3 bits (207), Expect = 7e-16 Identities = 123/545 (22%), Positives = 216/545 (39%), Gaps = 136/545 (24%) Query: 760 GDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPS 819 GD + A+F R + D ++ T S + A ++A S+ + F F+T++ Sbjct: 926 GDIDYCELNARFGFRNI--IADPVTFKTKSSYVALAT----LQAYTSMHLFFQFKTTSLD 979 Query: 820 GVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVR 879 G+ L N G ++ VEL + + FD+GNG NL S + ND++WH V Sbjct: 980 GLILYNSGDG-----NDFIVVEL-VKGYLHYVFDLGNG-ANLIKGSSNKPLNDNQWHNVM 1032 Query: 880 AEINVKQAR-LRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSAELK-----------RRPF 927 + +++D + + ++ LY+G + + F Sbjct: 1033 ISRDTSNLHTVKIDTKITTQITAGARN---LDLKSDLYIGGVAKETYKSLPKLVHAKEGF 1089 Query: 928 VGCLRAMRLNGVTLNLEGRA--------NASEGTSPNCTGHCAHPRLPCFHGGRCVERYS 979 GCL ++ LNG +L A EG S C C + G C++++ Sbjct: 1090 QGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDS------CSNQGVCLQQWD 1143 Query: 980 YYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGY 1039 ++CDC +T+F GP CN +PGT +++ S+ Sbjct: 1144 GFSCDCSMTSFSGPLCN-------DPGT-----------------TYIFSK--------- 1170 Query: 1040 IPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLY 1099 G G +P RP + + ++ FST AVL+ Sbjct: 1171 --------------GGGQITYKWPPNDRP---------STRADRLAIGFSTVQKEAVLVR 1207 Query: 1100 V--SSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSINITRVYRNLFI 1157 V SS + DY+ + I G + +++ +GT + + + DG+ H + TR N + Sbjct: 1208 VDSSSGLGDYLELHI-HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATL 1266 Query: 1158 QVDYFPLTEQKFSLLVDSQ---LDSPKALY-LGRVMETGVIDP--EIQRYNTPG------ 1205 QVD +P+ E+ + D++ + + Y LGRV++ ++D ++ +N+ Sbjct: 1267 QVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGG 1326 Query: 1206 ------FSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSE 1259 F G LSG+ +N + L M AE + + G + RLV E Sbjct: 1327 KEQGQPFQGQLSGLYYNGLKVLN--------MAAENDANIAIVGNV---------RLVGE 1369 Query: 1260 VPPEL 1264 VP + Sbjct: 1370 VPSSM 1374 Score = 61.2 bits (147), Expect = 7e-09 Identities = 61/268 (22%), Positives = 118/268 (44%), Gaps = 36/268 (13%) Query: 788 ISFHTGAA-LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPY---VRVELN 843 I+F T + + P A + +SF FRT+ P+G+ L + G P Q + ++V+ Sbjct: 522 ITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFF 581 Query: 844 TSR----DVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVD--HRPWV 897 + D+G+G + + + + ND EW+ V + + + + V+ P+ Sbjct: 582 AIEMLDGHLYLLLDMGSG--TIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYT 639 Query: 898 LRPMPLQTYIWMEYDQPLYVGS---------------AELKRRPFVGCLRAMRLNGVTLN 942 P ++ I ++ D LY+G L +VGC+R + ++G + + Sbjct: 640 A---PGESEI-LDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKD 695 Query: 943 LEGRAN--ASEGTSPNCTGHCAHPRL--PCFHGGRCVERYSYYTCDCDLTAFDGPYCNHD 998 + A ++ G P+C+ A P L PC + G C + ++ Y CDC T + G C + Sbjct: 696 IRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCERE 755 Query: 999 IGGF-FEPGTWMRYNLQSALRSAAREFS 1025 ++ +M+ L + + A + S Sbjct: 756 ATVLSYDGSMFMKIQLPVVMHTEAEDVS 783 Score = 46.2 bits (108), Expect = 2e-04 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 2/98 (2%) Query: 1065 PGRPVPGYRGPVYNVTGE-EVSFSFSTSSAPAVLLYVSSF-VRDYMAVLIKDDGTLQLRY 1122 PG R P +N E E+SF T SA ++LY D++ +++ G LQL + Sbjct: 34 PGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSF 93 Query: 1123 QLGTSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQVD 1160 + + L PV DG HS+ I R +RN + +D Sbjct: 94 SIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLFID 131 Score = 44.3 bits (103), Expect = 8e-04 Identities = 58/247 (23%), Positives = 92/247 (37%), Gaps = 31/247 (12%) Query: 776 LRCYGDRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRR 835 L C+ + S G RFP A ++SF +T + G+ L +C Sbjct: 21 LGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCD--- 77 Query: 836 PYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDH-- 893 ++ + L + +F + + + D ND WH VR + L +D Sbjct: 78 -FLELILTRGGRLQLSFSIFCAEPATLLA--DTPVNDGAWHSVRIRRQFRNTTLFIDQVE 134 Query: 894 RPWV-----LRPMPLQTYIWMEYDQPLYVGSAELK--------RRPFVGCLRAMRLNGVT 940 WV R M + + +++ P + +A LK R PF G +R +R+N Sbjct: 135 AKWVEVKSKRRDMTVFSGLFVG-GLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQ 193 Query: 941 L--------NLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDG 992 + L+ S G SP G + C +GG C CDC T F G Sbjct: 194 VLPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGV-CLNGGVCSVVDDQAVCDCSRTGFRG 252 Query: 993 PYCNHDI 999 C+ +I Sbjct: 253 KDCSQEI 259 Score = 42.7 bits (99), Expect = 0.002 Identities = 52/214 (24%), Positives = 78/214 (36%), Gaps = 34/214 (15%) Query: 385 VSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEG-QVNVSIAQSGRKKLQFAAGYRLNDGF 443 +SF+ +T GL+L+ +EL L+ G ++ +S + + A +NDG Sbjct: 54 MSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGA 113 Query: 444 WHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTS-YFFGGCP-------------- 488 WH V Q + + ID VE V V T S F GG P Sbjct: 114 WHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLAS 173 Query: 489 ----KPASRW--DCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITD 542 +P W D N + ++L VD V L G C + Sbjct: 174 VREREPFKGWIRDVRVNSS------QVLPVDSGEVKLDDEPPNSGG------GSPCEAGE 221 Query: 543 RCSPNMCEHDGRCYQSWDDFICYCELTGYKGETC 576 +C + G C D +C C TG++G+ C Sbjct: 222 EGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDC 255 Score = 41.2 bits (95), Expect = 0.007 Identities = 32/129 (24%), Positives = 62/129 (48%), Gaps = 16/129 (12%) Query: 175 LYFDGDDAISYRFP---RGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG--DYVTLELEG 229 ++ G I+Y++P R +R+ D A F T +K+ +L+ + + G DY+ L + Sbjct: 1167 IFSKGGGQITYKWPPNDRPSTRA--DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQ 1224 Query: 230 AHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGY--VQRFI 287 + + ++G+ I + ++ND +H VR R G + +D + ++R+ Sbjct: 1225 GKIGVKFNVGTDDI------AIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYP 1278 Query: 288 L-NGDFERL 295 N D ERL Sbjct: 1279 AGNNDNERL 1287 Score = 34.7 bits (78), Expect = 0.65 Identities = 45/168 (26%), Positives = 73/168 (43%), Gaps = 20/168 (11%) Query: 175 LYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLEL---EGAH 231 L F G + RFP+ + +F KT GL+L+ + +G LEL G Sbjct: 31 LEFPGAEGQWTRFPKW-NACCESEMSFQLKTRSARGLVLYFDD-EGFCDFLELILTRGGR 88 Query: 232 LLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFI-LNG 290 L L S+ + +P T+ A +ND WH VR+ R R+ +D +++ + Sbjct: 89 LQLSFSIFCA--EP----ATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKS 142 Query: 291 DFERLNLDTEMFIGGL-----VGAARKNLA---YRHNFRGCIENVIFN 330 + + + +F+GGL A + LA R F+G I +V N Sbjct: 143 KRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVN 190 Score = 32.7 bits (73), Expect = 2.5 Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 7/101 (6%) Query: 796 LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYV---RVELNTSRDVV-FA 851 ++ P + + DVS FR+ G+ + R + RV+L + D + Sbjct: 769 IQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRIN 828 Query: 852 FDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVD 892 + G E L + ND+EWH VR K +L VD Sbjct: 829 CNSSKGPETLFA---GYNLNDNEWHTVRVVRRGKSLKLTVD 866 >gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens] Length = 1712 Score = 130 bits (328), Expect = 7e-30 Identities = 118/449 (26%), Positives = 190/449 (42%), Gaps = 63/449 (14%) Query: 177 FDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHM 236 F G++ Y +S D +F+T +++GL+LH G DYV L L+ + L + Sbjct: 292 FKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHT-GKSADYVNLSLKSGAVWLVI 350 Query: 237 SLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGR---------------------DV 275 +LGS + G ND WH VRV R R D Sbjct: 351 NLGSGAFEA----LVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDG 406 Query: 276 NFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAAR-KNLAYRHNFRGCIENVIFN---- 330 T GY Q D+ L D +IGG A +NF GC+++V++ Sbjct: 407 ILTTTGYTQE-----DYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDF 461 Query: 331 RVNIADLAVRRHSRITFEGKVAFRCLDPVP-HPINFGGPHNFVQVPGFPRRGRLAVSFRF 389 ++ ++ LA ++ +G ++FRC D P+ F P FV +P + + ++S F Sbjct: 462 KLELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDF 521 Query: 390 RTWDLTGLLLFS---RLGDGLG---------HVELTLSEGQVNVSIAQ-SGRKKLQFAAG 436 RT + GLLLFS R G G G + + L +G + + + SG KL+ A+ Sbjct: 522 RTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLR-ASS 580 Query: 437 YRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPK------- 489 ++NDG W V+F IS++ + ++ + + GG P+ Sbjct: 581 RKVNDGEWCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGGLPEGGRVDLP 640 Query: 490 -PASRWDCHSNQTAFHGCMELLKVDGQLVNLT-LVEGRRLGFYAEVLFDTCGITDRCSPN 547 P W + + + GC+ L +DG+ +L L E + G F + +C+ Sbjct: 641 LPPEVWTA-ALRAGYVGCVRDLFIDGRSRDLRGLAEAQ--GAVGVAPFCSRETLKQCASA 697 Query: 548 MCEHDGRCYQSWDDFICYCELTGYKGETC 576 C + G C + W+ FIC C TG+ G C Sbjct: 698 PCRNGGVCREGWNRFICDCIGTGFLGRVC 726 Score = 110 bits (276), Expect = 7e-24 Identities = 110/429 (25%), Positives = 184/429 (42%), Gaps = 36/429 (8%) Query: 168 CPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG-DYVTLE 226 C +A +L +DG + P + DV + F ++ GL++ + D + LE Sbjct: 726 CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 784 Query: 227 LEGAHLLLHMSLGSSPI--QPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQ 284 L+G + L ++L + P G T+ AG LND WH VRV R G+ + ++D Sbjct: 785 LDGGQMKLTVNLDCLRVGCAPSKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTV 844 Query: 285 RFILNGDFERL---NLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRR 341 + G RL N++T G++ R NF G + ++FN D + Sbjct: 845 EGQMAGAHMRLEFHNIET-----GIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQC--K 897 Query: 342 HSRITF-EGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLF 400 IT+ E F V P+ F +++ + + + F+F+T GLLLF Sbjct: 898 DGDITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLF 957 Query: 401 SRLGDGLGHVELTLSEGQVN-VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQE--NHAV 457 + G+G + + L +G ++ V +G ++ + +ND WH V V+++ N Sbjct: 958 NS-GNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNV-VVSRDPGNVHT 1015 Query: 458 ISIDD------VEGAE-VRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELL 510 + ID GA + + L I + F PK + D F GC+ + Sbjct: 1016 LKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRD------GFQGCLASV 1069 Query: 511 KVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTG 570 ++G+L +L R+G +V G + C+ C + G C Q WD F C C +T Sbjct: 1070 DLNGRLPDLIADALHRIG---QVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTS 1126 Query: 571 YKGETCHTP 579 Y G C+ P Sbjct: 1127 YGGPVCNDP 1135 Score = 92.0 bits (227), Expect = 3e-18 Identities = 120/509 (23%), Positives = 200/509 (39%), Gaps = 130/509 (25%) Query: 796 LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVG 855 L ++A S+ + F F+T+AP G+ L N G ++ +EL + + FD+G Sbjct: 929 LALATLQAYASMHLFFQFKTTAPDGLLLFNSGNG-----NDFIVIEL-VKGYIHYVFDLG 982 Query: 856 NGDENLTVHSDDFEFNDDEWHLVRAEINVKQAR-LRVDHRPWVLRPMPLQTYIWMEYDQP 914 NG + +SD ND++WH V + L++D R + ++ Sbjct: 983 NGPSLMKGNSDK-PVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARN---LDLKGE 1038 Query: 915 LYVGSAE-----------LKRRPFVGCLRAMRLNGVTLNLEGRA--------NASEGTSP 955 LY+G R F GCL ++ LNG +L A +G S Sbjct: 1039 LYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPST 1098 Query: 956 NCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQS 1015 CT C + G C++++ +TCDC +T++ GP CN +PGT + Sbjct: 1099 TCTEES------CANQGVCLQQWDGFTCDCTMTSYGGPVCN-------DPGTTYIFGKGG 1145 Query: 1016 ALRSAAREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGP 1075 AL + Y P RP + Sbjct: 1146 ALIT-------------------------------------YTWPPNDRPSTRM------ 1162 Query: 1076 VYNVTGEEVSFSFSTSSAPAVLLYV--SSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQL 1133 + ++ FST AVL+ V +S + DY+ + I D GT+ + + +GT Sbjct: 1163 ------DRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-DQGTVGVIFNVGTDDITIDE 1215 Query: 1134 TTRPVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQ---LDSPKALY-LGRVM 1189 V+DG+ H + TR N +QVD +P+ E+ + D++ + + Y LGRV+ Sbjct: 1216 PNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVV 1275 Query: 1190 ETGVIDP--EIQRYNTPG------------FSGCLSGVRFNNVAPLKTHFRTPRPMTAEL 1235 + ++D ++ +N+ F G +SG+ +N + L + AE Sbjct: 1276 DEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVL--------ALAAES 1327 Query: 1236 AEALRVQGELSESNCGAMPRLVSEVPPEL 1264 +R +G L RLV E P L Sbjct: 1328 DPNVRTEGHL---------RLVGEGPSVL 1347 Score = 61.2 bits (147), Expect = 7e-09 Identities = 69/262 (26%), Positives = 121/262 (46%), Gaps = 36/262 (13%) Query: 794 AALRFPPIRANHSLDVSFYFRTSAPSGVFLENMG-------GPYCQWRRP-YVRVELNTS 845 A + P A + +S FRT+ P+G+ L + G G + +R Y +EL Sbjct: 502 AFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDG 561 Query: 846 RDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHR--PWVLRP--- 900 + D+G+G L S + ND EW V + + ++ + V+ R P++ Sbjct: 562 H-LYLLLDMGSGGIKLRASSR--KVNDGEWCHVDFQRDGRKGSISVNSRSTPFLATGDSE 618 Query: 901 -MPLQTYIWM-------EYDQPL--YVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANA- 949 + L++ +++ D PL V +A L R +VGC+R + ++G + +L G A A Sbjct: 619 ILDLESELYLGGLPEGGRVDLPLPPEVWTAAL-RAGYVGCVRDLFIDGRSRDLRGLAEAQ 677 Query: 950 -SEGTSPNCTGH----CAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGF-F 1003 + G +P C+ CA PC +GG C E ++ + CDC T F G C + + Sbjct: 678 GAVGVAPFCSRETLKQCASA--PCRNGGVCREGWNRFICDCIGTGFLGRVCEREATVLSY 735 Query: 1004 EPGTWMRYNLQSALRSAAREFS 1025 + +M+ L +A+ + A + S Sbjct: 736 DGSMYMKIMLPNAMHTEAEDVS 757 Score = 48.1 bits (113), Expect = 6e-05 Identities = 44/182 (24%), Positives = 72/182 (39%), Gaps = 13/182 (7%) Query: 153 WNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLL 212 W P L L L +AD L F G R+ R + +FS +T LL Sbjct: 7 WRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTNATRALL 66 Query: 213 LHAE-GAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRF 271 L+ + G D++ L L L L +L + +P T+ + D WH V + R Sbjct: 67 LYLDDGGDCDFLELLLVDGRLRLRFTLSCA--EP----ATLQLDTPVADDRWHMVLLTRD 120 Query: 272 GRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAAR------KNLAYRHNFRGCIE 325 R +DG + + + + +++F+GG+ R + Y FRG + Sbjct: 121 ARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLA 180 Query: 326 NV 327 N+ Sbjct: 181 NL 182 Score = 42.4 bits (98), Expect = 0.003 Identities = 56/231 (24%), Positives = 88/231 (38%), Gaps = 21/231 (9%) Query: 385 VSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLNDGFW 444 +SF RT LLL+ G +EL L +G++ + S + + D W Sbjct: 53 LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRW 112 Query: 445 HEVNFVAQENHAVISID-DVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTA- 502 H V +++D + AEVR S ++ + F GG P P R + T Sbjct: 113 HMVLLTRDARRTALAVDGEARAAEVR-SKRREMQVASDLFVGGIP-PDVRLSALTLSTVK 170 Query: 503 ----FHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSP--NMCEHDGRC- 555 F G + LK+ + L +G R G A+ L C+P N C + G C Sbjct: 171 YEPPFRGLLANLKLGERPPALLGSQGLR-GATADPL---------CAPARNPCANGGLCT 220 Query: 556 YQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSG 606 + + C C TG+ G+ C + A+ G+ G+G Sbjct: 221 VLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAG 271 Score = 40.4 bits (93), Expect = 0.012 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 2/79 (2%) Query: 1083 EVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLG-TSPYVYQLTTRPVTDG 1141 E+SFS T++ A+LLY+ L+ DG L+LR+ L P QL T PV D Sbjct: 52 ELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDT-PVADD 110 Query: 1142 QPHSINITRVYRNLFIQVD 1160 + H + +TR R + VD Sbjct: 111 RWHMVLLTRDARRTALAVD 129 Score = 40.4 bits (93), Expect = 0.012 Identities = 92/413 (22%), Positives = 147/413 (35%), Gaps = 76/413 (18%) Query: 872 DDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSAELKRR------ 925 DD WH+V + ++ L VD + + + D L+VG R Sbjct: 109 DDRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASD--LFVGGIPPDVRLSALTL 166 Query: 926 -------PFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRC-VER 977 PF G L ++L L G T+ CA R PC +GG C V Sbjct: 167 STVKYEPPFRGLLANLKLGERPPALLGSQGLRGATADPL---CAPARNPCANGGLCTVLA 223 Query: 978 YSYYTCDCDLTAFDGPYCNHDIGGFFEPG-TWMRYNLQSALRS---AAREFSHMLSRPVP 1033 CDC T F G +C+ + P + + S L S A R + + +P Sbjct: 224 PGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAGRGGAGDVHQPTK 283 Query: 1034 GYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSA 1093 G E +V + G + D P+ + T +E++ +F T Sbjct: 284 GKEE----------FVATFKGNEFFCYDLS---------HNPIQSST-DEITLAFRTLQR 323 Query: 1094 PAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPV----TDGQPHSINIT 1149 ++L+ DY+ + +K G + L LG+ ++ PV D H + +T Sbjct: 324 NGLMLHTGKSA-DYVNLSLK-SGAVWLVINLGSG--AFEALVEPVNGKFNDNAWHDVRVT 379 Query: 1150 RVYRN---------------LFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVI 1194 R R + I VD LT ++ + L S Y+G T + Sbjct: 380 RNLRQHAGIGHAMVNKLHYLVTISVDGI-LTTTGYTQEDYTMLGSDDFFYIGGSPNTADL 438 Query: 1195 DPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAE-ALRVQGELS 1246 N F GCL V + N F+ A+ + +++QG+LS Sbjct: 439 PGSPVSNN---FMGCLKDVVYKN-----NDFKLELSRLAKEGDPKMKLQGDLS 483 >gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens] Length = 1061 Score = 115 bits (288), Expect = 3e-25 Identities = 108/422 (25%), Positives = 184/422 (43%), Gaps = 22/422 (5%) Query: 168 CPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG-DYVTLE 226 C +A IL +DG + P + DV +F F ++ GLL+ D + LE Sbjct: 306 CEREASILSYDGSMYMKIIMPMVMHTEAEDV-SFRFMSQRAYGLLVATTSRDSADTLRLE 364 Query: 227 LEGAHLLLHMSLGSSPIQ--PRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQ 284 L+G + L ++L I G T+ AG LND WH VRV R G+ + T+D V Sbjct: 365 LDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVA 424 Query: 285 RFILNGDFERL---NLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRR 341 + GD RL N++T G++ R +F G +++++FN + DL + Sbjct: 425 EGTMVGDHTRLEFHNIET-----GIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLC--K 477 Query: 342 HSRITF-EGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLF 400 + I + E K F + + P+ F +++ + + + F+F+T G +LF Sbjct: 478 NGDIDYCELKARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILF 537 Query: 401 SRLGDGLGHVELTLSEGQVN-VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHA-VI 458 + GDG + + L +G ++ V +G ++ + LND WH V ++ + Sbjct: 538 NS-GDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSL 596 Query: 459 SIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWD-CHSNQTAFHGCMELLKVDGQLV 517 +D +V L G Y G S +++ F GC+ + ++G+L Sbjct: 597 KVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLP 656 Query: 518 NLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCH 577 +L R G ++ G + C + C + G C Q W+ F C C +T Y G C+ Sbjct: 657 DLINDALHRSG---QIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCN 713 Query: 578 TP 579 P Sbjct: 714 DP 715 Score = 84.7 bits (208), Expect = 5e-16 Identities = 74/320 (23%), Positives = 127/320 (39%), Gaps = 53/320 (16%) Query: 295 LNLDTEMFIGGLVGAAR-KNLAYRHNFRGCIENVIFN----RVNIADLAVRRHSRITFEG 349 L D ++GG A +NF GC++ V++ R+ ++ LA +++ G Sbjct: 2 LGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYG 61 Query: 350 KVAFRCLDPVP-HPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSR------ 402 +V F+C + PINF P ++ +P + + ++SF FRT + GL+LF+ Sbjct: 62 EVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQER 121 Query: 403 -----------------LGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLNDGFWH 445 L DG ++ L + G + V Q + NDG W+ Sbjct: 122 KDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQK-----------KANDGEWY 170 Query: 446 EVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPK-------PASRWDCHS 498 V+ IS++ ++ + GG P+ P W Sbjct: 171 HVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAML 230 Query: 499 NQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCG--ITDRCSPNMCEHDGRCY 556 N + GC+ L +DG+ N+ + + A + +C +C C+++ C Sbjct: 231 NY-GYVGCIRDLFIDGRSKNIRQLAEMQ---NAAGVKSSCSRMSAKQCDSYPCKNNAVCK 286 Query: 557 QSWDDFICYCELTGYKGETC 576 W+ FIC C TGY G TC Sbjct: 287 DGWNRFICDCTGTGYWGRTC 306 Score = 82.4 bits (202), Expect = 3e-15 Identities = 101/427 (23%), Positives = 174/427 (40%), Gaps = 97/427 (22%) Query: 760 GDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPPIRANHSLDVSFYFRTSAP 818 GD + +A+F LR + + ++F T ++ L ++A S+ + F F+T++P Sbjct: 479 GDIDYCELKARFGLRNIIA-------DPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSP 531 Query: 819 SGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWH-L 877 G L N G ++ VEL + + FD+GNG N+ + D ND++WH + Sbjct: 532 DGFILFNSGDG-----NDFIAVEL-VKGYIHYVFDLGNGP-NVIKGNSDRPLNDNQWHNV 584 Query: 878 VRAEINVKQARLRVDHRPWV-----LRPMPLQTYIWME-YDQPLYVGSAEL--KRRPFVG 929 V N L+VD + + + L+ ++M Q +Y +L R F G Sbjct: 585 VITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQG 644 Query: 930 CLRAMRLNGVTLNLEGRA--------NASEGTSPNCTGHCAHPRLPCFHGGRCVERYSYY 981 CL ++ LNG +L A EG S C C + G C++++ + Sbjct: 645 CLASVDLNGRLPDLINDALHRSGQIERGCEGPSTTCQEDS------CANQGVCMQQWEGF 698 Query: 982 TCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYIP 1041 TCDC +T++ G CN +PG Sbjct: 699 TCDCSMTSYSGNQCN-------DPGA---------------------------------- 717 Query: 1042 GYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVS 1101 Y+ G G G L +P RP + + ++ FST+ +L+ + Sbjct: 718 -----TYIFGKSG-GLILYTWPANDRP---------STRSDRLAVGFSTTVKDGILVRID 762 Query: 1102 SF--VRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQV 1159 S + D++ + I + G + + + +GT + PV DG+ H + TR N +QV Sbjct: 763 SAPGLGDFLQLHI-EQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQV 821 Query: 1160 DYFPLTE 1166 D +P+ E Sbjct: 822 DNWPVNE 828 Score = 52.8 bits (125), Expect = 2e-06 Identities = 58/269 (21%), Positives = 105/269 (39%), Gaps = 38/269 (14%) Query: 788 ISFHTGAA-LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSR 846 I+F T A + P +SF FRT+ P+G+ L G P R R + NT Sbjct: 76 INFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQ---ERKDARSQKNTKV 132 Query: 847 D----------VVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPW 896 D + D+G+G + V + + ND EW+ V + + + + V+ R Sbjct: 133 DFFAVELLDGNLYLLLDMGSG--TIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRT 190 Query: 897 VLRPMPLQTYIWMEYDQPLYVGSAELKRRP---------------FVGCLRAMRLNGVTL 941 + +E D +Y+G R +VGC+R + ++G + Sbjct: 191 PFTASGESEILDLEGD--MYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSK 248 Query: 942 NLEGRANASE--GTSPNCTGHCAHP--RLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNH 997 N+ A G +C+ A PC + C + ++ + CDC T + G C Sbjct: 249 NIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCER 308 Query: 998 DIGGF-FEPGTWMRYNLQSALRSAAREFS 1025 + ++ +M+ + + + A + S Sbjct: 309 EASILSYDGSMYMKIIMPMVMHTEAEDVS 337 Score = 52.4 bits (124), Expect = 3e-06 Identities = 47/206 (22%), Positives = 87/206 (42%), Gaps = 37/206 (17%) Query: 120 NSTFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDG 179 ++ F G + E +D+ + R RI G++ ++ C A + Sbjct: 25 SNNFMGCLKEVVYKNNDIRLELS-RLARIADTKMKIYGEV-----VFKCENVATL----- 73 Query: 180 DDAISYRFPRG-VSRSLWDV-----FAFSFKTEEKDGLLLHAEG-------------AQG 220 D I++ P +S W+ +F F+T E +GL+L G + Sbjct: 74 -DPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKV 132 Query: 221 DYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLD 280 D+ +EL +L L + +GS I+ + ND W++V + R GR +++ Sbjct: 133 DFFAVELLDGNLYLLLDMGSGTIKVKATQKKA------NDGEWYHVDIQRDGRSGTISVN 186 Query: 281 GYVQRFILNGDFERLNLDTEMFIGGL 306 F +G+ E L+L+ +M++GGL Sbjct: 187 SRRTPFTASGESEILDLEGDMYLGGL 212 Score = 42.0 bits (97), Expect = 0.004 Identities = 41/144 (28%), Positives = 66/144 (45%), Gaps = 8/144 (5%) Query: 1080 TGEEVSFSFSTSSAPAVLLYVSSFVRDYMAV-LIKDDGTLQLRYQLGTSPYVYQLTT-RP 1137 T + F F T+S +L+ S D++AV L+K G + + LG P V + + RP Sbjct: 518 TSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVK--GYIHYVFDLGNGPNVIKGNSDRP 575 Query: 1138 VTDGQPHSINITRVYRNLF-IQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDP 1196 + D Q H++ ITR N ++VD +T+ + LD LY+ + + + Sbjct: 576 LNDNQWHNVVITRDNSNTHSLKVDTKVVTQ---VINGAKNLDLKGDLYMAGLAQGMYSNL 632 Query: 1197 EIQRYNTPGFSGCLSGVRFNNVAP 1220 + GF GCL+ V N P Sbjct: 633 PKLVASRDGFQGCLASVDLNGRLP 656 Score = 42.0 bits (97), Expect = 0.004 Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 20/168 (11%) Query: 197 DVFAFSFKTEEKDGLLLHAEGAQ--GDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSA 254 D A F T KDG+L+ + A GD++ L +E + + ++G+ I + T V Sbjct: 743 DRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPV-- 800 Query: 255 GGVLNDQHWHYVRVDRFGRDVNFTLDGYV--QRFILNGDFERLNLDTEMFIGGLVGAARK 312 ND +H VR R G + +D + + + N ++ IGG Sbjct: 801 ----NDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKG--- 853 Query: 313 NLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVP 360 F+G + + ++ + + ++A + I G V R + VP Sbjct: 854 -----RLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSV--RLVGEVP 894 >gi|169184330 PREDICTED: novel protein similar to contactin associated protein-like 3 (CNTNAP3) [Homo sapiens] Length = 291 Score = 103 bits (257), Expect = 1e-21 Identities = 55/154 (35%), Positives = 93/154 (60%), Gaps = 4/154 (2%) Query: 1079 VTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGT--SPYVYQLTTR 1136 +T E ++ SF T+ P++LLYVSSF +Y++V++ ++G+LQ+RY+L +P + + Sbjct: 40 LTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFK 99 Query: 1137 PVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDP 1196 + DGQ H + I R + ++V+ +++ L ++ ++ K+L LG+V+E DP Sbjct: 100 NMADGQLHQVKINREEAVVMVEVNQS--AKKQVILSSGTEFNAVKSLILGKVLEAAGADP 157 Query: 1197 EIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRP 1230 + +R T GF+GCLS VRF APLK R P Sbjct: 158 DTRRAATSGFTGCLSAVRFGCAAPLKAALRPSGP 191 >gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo sapiens] Length = 2923 Score = 74.3 bits (181), Expect = 7e-13 Identities = 115/483 (23%), Positives = 173/483 (35%), Gaps = 110/483 (22%) Query: 189 RGVSRSLWDVFAFSFKTEEKDGLLLHAE--GAQGDYVTLELEGAHLLLHMSLGSSPIQPR 246 RG+ + A SF T+E+DGLLL+ + D+V LE+ + L S G S Sbjct: 1381 RGLRQRFHFTLALSFATKERDGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGEST---- 1436 Query: 247 PGHTTVSA---GGVLNDQHWHYVRVDRFGRDVN----------------FTLDGYVQRFI 287 TTVS GGV +D WH V++ + + + T+DG Sbjct: 1437 ---TTVSPFVPGGV-SDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVTVDGCDTGVA 1492 Query: 288 LN-----------------GDFERLNLDTEMFIGGLVGAARKNLAYRHNFRGCIEN--VI 328 L G + L+L + +GG+ F GC+ N V Sbjct: 1493 LRFGSVLGNYSCAAQGTQGGSKKSLDLTGPLLLGGVPDLPESFPVRMRQFVGCMRNLQVD 1552 Query: 329 FNRVNIADLAVRR-------------HSRITFEGKV------AFRCLDPVPHPINFGG-- 367 +++AD S G AF C P+ FGG Sbjct: 1553 SRHIDMADFIANNGTVPGCPAKKNVCDSNTCHNGGTCVNQWDAFSC----ECPLGFGGKS 1608 Query: 368 -------PHNFVQVP-------GFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELT 413 P +F+ P +S FRT G+LL + G + L Sbjct: 1609 CAQEMANPQHFLGSSLVAWHGLSLPISQPWYLSLMFRTRQADGVLL-QAITRGRSTITLQ 1667 Query: 414 LSEGQVNVSIAQSGRK--KLQFAAGYRLNDGFWHEVNFVAQEN----HAVISID-DVEGA 466 L EG V +S+ +G + L+ G R NDG WH + HA++S D + A Sbjct: 1668 LREGHVMLSVEGTGLQASSLRLEPG-RANDGDWHHAQLALGASGGPGHAILSFDYGQQRA 1726 Query: 467 EVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVE--- 523 E + L ++ GG P PA F GC++ ++V + ++ Sbjct: 1727 EGNLGPRLHGLHLSNITVGGIPGPAG-----GVARGFRGCLQGVRVSDTPEGVNSLDPSH 1781 Query: 524 GRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKE 583 G + + C + D C N C + C WD + C C+ GY G+ C Sbjct: 1782 GESIN-----VEQGCSLPDPCDSNPCPANSYCSNDWDSYSCSCD-PGYYGDNCTNVCDLN 1835 Query: 584 SCE 586 CE Sbjct: 1836 PCE 1838 Score = 51.2 bits (121), Expect = 7e-06 Identities = 61/248 (24%), Positives = 96/248 (38%), Gaps = 53/248 (21%) Query: 369 HNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFS-RLGDGLGHVELTLSEGQVNV--SIAQ 425 H+F+ G +R ++ F T + GLLL++ R + V L + + QV + S + Sbjct: 1375 HSFITFRGLRQRFHFTLALSFATKERDGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGE 1434 Query: 426 SGRKKLQFAAGYRLNDGFWHEVNF----------------VAQENHAVISIDDVE-GAEV 468 S F G ++DG WH V +++ AV+++D + G + Sbjct: 1435 STTTVSPFVPG-GVSDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVTVDGCDTGVAL 1493 Query: 469 RVSYPL-----------------LIRTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLK 511 R L L TG GG P + Q F GCM L+ Sbjct: 1494 RFGSVLGNYSCAAQGTQGGSKKSLDLTG-PLLLGGVPDLPESFPVRMRQ--FVGCMRNLQ 1550 Query: 512 VDGQLVNLT---LVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCEL 568 VD + +++ G G A+ + C N C + G C WD F C C L Sbjct: 1551 VDSRHIDMADFIANNGTVPGCPAK--------KNVCDSNTCHNGGTCVNQWDAFSCECPL 1602 Query: 569 TGYKGETC 576 G+ G++C Sbjct: 1603 -GFGGKSC 1609 Score = 41.2 bits (95), Expect = 0.007 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 3/82 (3%) Query: 919 SAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHC-AHPRLPCFHGGRCVER 977 S ++ R FVGC+R ++++ +++ A+ GT P C C +GG CV + Sbjct: 1534 SFPVRMRQFVGCMRNLQVDSRHIDMADFI-ANNGTVPGCPAKKNVCDSNTCHNGGTCVNQ 1592 Query: 978 YSYYTCDCDLTAFDGPYCNHDI 999 + ++C+C L F G C ++ Sbjct: 1593 WDAFSCECPL-GFGGKSCAQEM 1613 >gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo sapiens] Length = 3014 Score = 72.0 bits (175), Expect = 4e-12 Identities = 109/489 (22%), Positives = 186/489 (38%), Gaps = 118/489 (24%) Query: 189 RGVSRSLWDVFAFSFKTEEKDGLLLHAE--GAQGDYVTLELEGAHLLLHMSLGSSPIQPR 246 RG+ + + +F T+E++GLLL+ + D++ LE+ + L S G + Sbjct: 1456 RGLRQRFHFTISLTFATQERNGLLLYNGRFNEKHDFIALEIVDEQVQLTFSAGETTTTVA 1515 Query: 247 PGHTTVSAGGVLNDQHWHYVRVD-----------------------------------RF 271 P V +G ++D WH V+V RF Sbjct: 1516 P---KVPSG--VSDGRWHSVQVQYYNKPNIGHLGLPHGPSGEKMAVVTVDDCDTTMAVRF 1570 Query: 272 GRDV-NFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFN 330 G+D+ N++ + G + L+L + +GG+ + F GC+ N+ + Sbjct: 1571 GKDIGNYSCAAQGTQ---TGSKKSLDLTGPLLLGGVPNLPEDFPVHNRQFVGCMRNLSVD 1627 Query: 331 RVNIADLAVRRHSRITFEGKVAFR---------------------------------CLD 357 N+ D+A + T EG A R C Sbjct: 1628 GKNV-DMAGFIANNGTREGCAARRNFCDGRRCQNGGTCVNRWNMYLCECPLRFGGKNCEQ 1686 Query: 358 PVPHPINFGGP--------HNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGH 409 +PHP F G + + VP + L + FR R D L+ + G Sbjct: 1687 AMPHPQLFSGESVVSWSDLNIIISVPWY-----LGLMFRTRKEDSV-LMEATSGGPTSFR 1740 Query: 410 VELTLSEGQVNVSIAQSGRKKLQFAAGYRLNDGFWH----EVNFVAQENH----AVISID 461 +++ + Q VS S + + + G R+ DG WH E+ V +++ +++D Sbjct: 1741 LQILNNYLQFEVSHGPSDVESVMLS-GLRVTDGEWHHLLIELKNVKEDSEMKHLVTMTLD 1799 Query: 462 ---DVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVN 518 D A++ P L T S GG + D S + F GCM+ +++ G N Sbjct: 1800 YGMDQNKADIGGMLPGL--TVRSVVVGGASE-----DKVSVRRGFRGCMQGVRMGGTPTN 1852 Query: 519 L-TLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCH 577 + TL L + D C + D C+ + C + RC+ +W+D+ C C+ GY G C Sbjct: 1853 VATLNMNNALKVRVK---DGCDVDDPCTSSPCPPNSRCHDAWEDYSCVCD-KGYLGINCV 1908 Query: 578 TPLYKESCE 586 + CE Sbjct: 1909 DACHLNPCE 1917 Score = 55.5 bits (132), Expect = 4e-07 Identities = 65/256 (25%), Positives = 98/256 (38%), Gaps = 67/256 (26%) Query: 368 PHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLL----FSRLGDGLG------HVELTLSEG 417 P +FV G +R +S F T + GLLL F+ D + V+LT S G Sbjct: 1449 PQSFVTFRGLRQRFHFTISLTFATQERNGLLLYNGRFNEKHDFIALEIVDEQVQLTFSAG 1508 Query: 418 QVNVSIAQSGRKKLQFAAGYRLNDGFWHEVNF----------------VAQENHAVISID 461 + ++A + +G ++DG WH V + E AV+++D Sbjct: 1509 ETTTTVAP------KVPSG--VSDGRWHSVQVQYYNKPNIGHLGLPHGPSGEKMAVVTVD 1560 Query: 462 DVE-------GAEV-----------RVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTAF 503 D + G ++ S L TG GG P + H+ Q F Sbjct: 1561 DCDTTMAVRFGKDIGNYSCAAQGTQTGSKKSLDLTG-PLLLGGVPNLPEDFPVHNRQ--F 1617 Query: 504 HGCMELLKVDGQLVNLT---LVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWD 560 GCM L VDG+ V++ G R G A F C C++ G C W+ Sbjct: 1618 VGCMRNLSVDGKNVDMAGFIANNGTREGCAARRNF--------CDGRRCQNGGTCVNRWN 1669 Query: 561 DFICYCELTGYKGETC 576 ++C C L + G+ C Sbjct: 1670 MYLCECPLR-FGGKNC 1684 Score = 46.6 bits (109), Expect = 2e-04 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 7/74 (9%) Query: 925 RPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGH---CAHPRLPCFHGGRCVERYSYY 981 R FVGC+R + ++G +++ G A+ GT C C R C +GG CV R++ Y Sbjct: 1615 RQFVGCMRNLSVDGKNVDMAGFI-ANNGTREGCAARRNFCDGRR--CQNGGTCVNRWNMY 1671 Query: 982 TCDCDLTAFDGPYC 995 C+C L F G C Sbjct: 1672 LCECPL-RFGGKNC 1684 Score = 34.7 bits (78), Expect = 0.65 Identities = 44/187 (23%), Positives = 71/187 (37%), Gaps = 30/187 (16%) Query: 967 PCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSH 1026 PC GRC R YTC+C F G +C D + Sbjct: 1371 PCGANGRCRSREGGYTCEC-FEDFTGEHCEVDA------------RSGRCANGVCKNGGT 1417 Query: 1027 MLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRG--PVYNVTGEEV 1084 ++ + G+ PG Y P + P + +RG ++ T + Sbjct: 1418 CVNLLIGGFHCVCPPG--------EYERPYCEVTTRSFPPQSFVTFRGLRQRFHFT---I 1466 Query: 1085 SFSFSTSSAPAVLLYVSSF--VRDYMAVLIKDDGTLQLRYQLG-TSPYVYQLTTRPVTDG 1141 S +F+T +LLY F D++A+ I D+ +QL + G T+ V V+DG Sbjct: 1467 SLTFATQERNGLLLYNGRFNEKHDFIALEIVDE-QVQLTFSAGETTTTVAPKVPSGVSDG 1525 Query: 1142 QPHSINI 1148 + HS+ + Sbjct: 1526 RWHSVQV 1532 Score = 32.7 bits (73), Expect = 2.5 Identities = 19/68 (27%), Positives = 28/68 (41%), Gaps = 7/68 (10%) Query: 924 RRPFVGCLRAMRLNGV-----TLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERY 978 RR F GC++ +R+ G TLN+ + C PC RC + + Sbjct: 1834 RRGFRGCMQGVRMGGTPTNVATLNMNNALKVRVKDGCDVDDPCTSS--PCPPNSRCHDAW 1891 Query: 979 SYYTCDCD 986 Y+C CD Sbjct: 1892 EDYSCVCD 1899 >gi|38788416 laminin, alpha 1 precursor [Homo sapiens] Length = 3075 Score = 70.5 bits (171), Expect = 1e-11 Identities = 86/324 (26%), Positives = 129/324 (39%), Gaps = 37/324 (11%) Query: 202 SFKTEEKDGLLLH-AEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLND 260 S +T GL+ + A Q DY L+L G L LG G T VS +L+D Sbjct: 2742 SIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGK-------GRTKVSHPALLSD 2794 Query: 261 QHWHYVRVDRFGRDVNFTLDGYVQRFI-LNGDFERLNLDTEMFIGGLVG--AARKNLAYR 317 WH V+ D R T+DG + + GD L+++ ++GGL ARK Sbjct: 2795 GKWHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNIT 2854 Query: 318 HNFRGCIENVIFNRVNI-ADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQV-P 375 H+ CI +V N + D V S T RC F G V Sbjct: 2855 HSIPACIGDVTVNSKQLDKDSPV---SAFTVN-----RCYAVAQEGTYFDGSGYAALVKE 2906 Query: 376 GFPRRGRLAVSFRFRTWDLTGLLL--FSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQF 433 G+ + + ++ FRT G+LL + D +G L L +G+V + + Sbjct: 2907 GYKVQSDVNITLEFRTSSQNGVLLGISTAKVDAIG---LELVDGKVLFHVNNGAGR---I 2960 Query: 434 AAGYR------LNDGFWHEVNFVAQENHAVISID-DVEGAEVRVSYPLLIRTGTSYFFGG 486 A Y L DG WH + ++ + +D + GAE + + T + GG Sbjct: 2961 TAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGG 3020 Query: 487 CPKPASRWDCHSNQTAFHGCMELL 510 P + C +QT+F GC+ L Sbjct: 3021 YPAGVKQ-KCLRSQTSFRGCLRKL 3043 Score = 54.7 bits (130), Expect = 6e-07 Identities = 64/286 (22%), Positives = 108/286 (37%), Gaps = 28/286 (9%) Query: 191 VSRSLWDVFAFSFKTEEKDGLLLH-AEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGH 249 +S + ++ + KT+E D LL + D++ +E+ + LGS G Sbjct: 2134 ISSTNYNTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGS-------GS 2186 Query: 250 TTVSAGGV-LNDQHWHYVRVDRFGR---------DVNFTLDGYVQRFILNGDFERLNLDT 299 T + ++D WH + V RFG N + + +N T Sbjct: 2187 TRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDVNNST 2246 Query: 300 EMFIGGLVGAARKNLAYR-HNFRGCIENVIFNRVNIADLAVRRHSRITFEGKV--AFRCL 356 MF+GGL G +K+ A + +F+GC+ N +I + I EGK F Sbjct: 2247 LMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIG-----LWNYIEREGKCRGCFGSS 2301 Query: 357 DPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSE 416 +F G V P + F T+ GLLL+ + + L Sbjct: 2302 QNEDPSFHFDGSGYSVVEKSLPATVTQIIML-FNTFSPNGLLLYLGSYGTKDFLSIELFR 2360 Query: 417 GQVNVSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDD 462 G+V V + G + R N+G W+++ F V+++ D Sbjct: 2361 GRVKV-MTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVID 2405 Score = 50.4 bits (119), Expect = 1e-05 Identities = 96/426 (22%), Positives = 180/426 (42%), Gaps = 67/426 (15%) Query: 153 WNPRGKIGLRLGLYGCPYKAD-ILYFDGD--DAISYRFPRGVSRSLWDVFAFSFKTEEKD 209 WN + G G +G D +FDG + P V++ + F T + Sbjct: 2285 WNYIEREGKCRGCFGSSQNEDPSFHFDGSGYSVVEKSLPATVTQII-----MLFNTFSPN 2339 Query: 210 GLLLHAEGAQG--DYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVR 267 GLLL+ G+ G D++++EL + + LGS PI T+ N+ W+ + Sbjct: 2340 GLLLYL-GSYGTKDFLSIELFRGRVKVMTDLGSGPI-------TLLTDRRYNNGTWYKIA 2391 Query: 268 VDRFGRD-VNFTLDGYV---------QRFILNGDFERLNLDTEMFIGGLVGA--ARKNLA 315 R + V +D Y + + D RL+ D +++GGL + R+ + Sbjct: 2392 FQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKDP-IYVGGLPRSRVVRRGVT 2450 Query: 316 YRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINF--GGPHNFVQ 373 + +F GCI+N+ +R + + R+S +G + L+P+ ++F GG +++ Sbjct: 2451 TK-SFVGCIKNLEISR---STFDLLRNSYGVRKGCL----LEPI-RSVSFLKGG---YIE 2498 Query: 374 VPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGD-------GLGHV---ELTLSEGQVNVSI 423 +P F T + +G++L + GD HV + L G + V + Sbjct: 2499 LPPKSLSPESEWLVTFATTNSSGIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHV 2558 Query: 424 AQSG----RKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRT- 478 RK L A +DG H ++ V + +D+ E+++ + RT Sbjct: 2559 NPGDGTGLRKALLHAPTGTCSDGQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTI 2618 Query: 479 -GTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDT 537 ++ + GG P+ + + +FHGC++ L + NL L++ + +V DT Sbjct: 2619 NVSNLYVGGIPE-GEGTSLLTMRRSFHGCIKNL-----IFNLELLDFNSAVGHEQVDLDT 2672 Query: 538 CGITDR 543 C +++R Sbjct: 2673 CWLSER 2678 Score = 39.3 bits (90), Expect = 0.026 Identities = 27/83 (32%), Positives = 42/83 (50%), Gaps = 5/83 (6%) Query: 1135 TRPVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVME-TGV 1193 T +DGQ HSI++ R R + +Q+D E K LV+S+ + LY+G + E G Sbjct: 2575 TGTCSDGQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGT 2634 Query: 1194 IDPEIQRYNTPGFSGCLSGVRFN 1216 ++R F GC+ + FN Sbjct: 2635 SLLTMRR----SFHGCIKNLIFN 2653 >gi|10518506 coagulation factor VIII isoform b precursor [Homo sapiens] Length = 216 Score = 70.1 bits (170), Expect = 1e-11 Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 10/137 (7%) Query: 40 ASSYYSLLTA---PRFARLH---GISGWSPRIGDPNPWLQIDLMKKHRIRAVATQG--SF 91 ASSY++ + A P ARLH + W P++ +P WLQ+D K ++ V TQG S Sbjct: 76 ASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSL 135 Query: 92 NSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTARYIRIVPL 151 + +V +++ WT F+Q G F GN + V + L RY+RI P Sbjct: 136 LTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQ 195 Query: 152 AWNPRGKIGLRLGLYGC 168 +W +I LR+ + GC Sbjct: 196 SW--VHQIALRMEVLGC 210 Score = 32.3 bits (72), Expect = 3.2 Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 2/46 (4%) Query: 123 FFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGC 168 FFGNV+ S + + + ARYIR+ P ++ R LR+ L GC Sbjct: 10 FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST--LRMELMGC 53 >gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens] Length = 2351 Score = 70.1 bits (170), Expect = 1e-11 Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 10/137 (7%) Query: 40 ASSYYSLLTA---PRFARLH---GISGWSPRIGDPNPWLQIDLMKKHRIRAVATQG--SF 91 ASSY++ + A P ARLH + W P++ +P WLQ+D K ++ V TQG S Sbjct: 2211 ASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSL 2270 Query: 92 NSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTARYIRIVPL 151 + +V +++ WT F+Q G F GN + V + L RY+RI P Sbjct: 2271 LTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQ 2330 Query: 152 AWNPRGKIGLRLGLYGC 168 +W +I LR+ + GC Sbjct: 2331 SW--VHQIALRMEVLGC 2345 Score = 60.5 bits (145), Expect = 1e-08 Identities = 39/129 (30%), Positives = 70/129 (54%), Gaps = 15/129 (11%) Query: 49 APRFARLH---GISGWSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWD--WVTRYMLL 103 AP+ ARLH I+ WS + +P W+++DL+ I + TQG+ + ++++++++ Sbjct: 2066 APKLARLHYSGSINAWSTK--EPFSWIKVDLLAPMIIHGIKTQGARQKFSSLYISQFIIM 2123 Query: 104 YGDRVDSWTPFYQRGHNS----TFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKI 159 Y W + RG+++ FFGNV+ S + + + ARYIR+ P ++ R Sbjct: 2124 YSLDGKKWQTY--RGNSTGTLMVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST- 2180 Query: 160 GLRLGLYGC 168 LR+ L GC Sbjct: 2181 -LRMELMGC 2188 >gi|105990535 coagulation factor V precursor [Homo sapiens] Length = 2224 Score = 68.6 bits (166), Expect = 4e-11 Identities = 41/126 (32%), Positives = 66/126 (52%), Gaps = 9/126 (7%) Query: 50 PRFARLHG---ISGWSPRIGDPNPWLQIDLMKKHRIRAVATQG--SFNSWDWVTRYMLLY 104 P ARL+ ++ W + + WL+IDL+K +I A+ TQG S +S +V Y + Y Sbjct: 2098 PFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHY 2157 Query: 105 GDRVDSWTPFYQRGH--NSTFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLR 162 ++ W P+ + + F GN N V++ + +R+IR++P WN I LR Sbjct: 2158 SEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQ--SIALR 2215 Query: 163 LGLYGC 168 L L+GC Sbjct: 2216 LELFGC 2221 Score = 44.7 bits (104), Expect = 6e-04 Identities = 43/134 (32%), Positives = 62/134 (46%), Gaps = 21/134 (15%) Query: 50 PRFARLHG---ISGWSPRI----GDPNPWLQIDLMKKHRIRAVATQGS--FNSWDWVTRY 100 PR ARL+ + WS PW+Q+D+ K+ I + TQG+ + + T + Sbjct: 1934 PRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGIQTQGAKHYLKSCYTTEF 1993 Query: 101 MLLYGDRVDSWTPFYQRGHNST-----FFGNVNESAVVRHDLHFHFTARYIRIVPL-AWN 154 + Y +W F +G NST F GN + S + + ARYIRI P A+N Sbjct: 1994 YVAYSSNQINWQIF--KG-NSTRNVMYFNGNSDASTIKENQFDPPIVARYIRISPTRAYN 2050 Query: 155 PRGKIGLRLGLYGC 168 + LRL L GC Sbjct: 2051 ---RPTLRLELQGC 2061 >gi|10835083 X-linked juvenile retinoschisis protein precursor [Homo sapiens] Length = 224 Score = 68.6 bits (166), Expect = 4e-11 Identities = 45/134 (33%), Positives = 73/134 (54%), Gaps = 8/134 (5%) Query: 43 YYSLLTAPRFARLHGIS---GWSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTR 99 +YS TA + ARL+ W + D + WLQIDL + I + TQG + +W+T+ Sbjct: 92 WYSSWTANK-ARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQGRCDIDEWMTK 150 Query: 100 YMLLYG-DRVDSWTPFY-QRGHNSTFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRG 157 Y + Y D +W + Q G+N F+GN + ++ V++ L +R+IR++PL W+ R Sbjct: 151 YSVQYRTDERLNWIYYKDQTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVR- 209 Query: 158 KIGLRLGLYGCPYK 171 I +R+ L C K Sbjct: 210 -IAIRMELLECVSK 222 >gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sapiens] Length = 756 Score = 68.2 bits (165), Expect = 5e-11 Identities = 35/111 (31%), Positives = 52/111 (46%), Gaps = 2/111 (1%) Query: 61 WSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSW--DWVTRYMLLYGDRVDSWTPFYQRG 118 W D W+++D + R V TQG + W DWVT Y ++ + +W Sbjct: 184 WCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGS 243 Query: 119 HNSTFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCP 169 + F GN + V ++L ARYIRI P +W G I +R+ + GCP Sbjct: 244 GDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCP 294 >gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] Length = 4391 Score = 67.8 bits (164), Expect = 7e-11 Identities = 112/466 (24%), Positives = 184/466 (39%), Gaps = 73/466 (15%) Query: 793 GAALRFPPI-RANHSLDVSFYFRTSAPSGVFLENMG--GPYCQWRRPYVRVELNTSRDVV 849 G+ L P + +H L + F+ AP GV L + G GP +V + + + Sbjct: 3936 GSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGKSGPV----EDFVSLAM-VGGHLE 3990 Query: 850 FAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMP------- 902 F +++G+G L V WH V AE K LRV+ VLR P Sbjct: 3991 FRYELGSG---LAVLRSAEPLALGRWHRVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLN 4047 Query: 903 LQTYIWMEYDQP-LYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHC 961 L T +++ +P + + A F GC+ + +NG L+L S+G C Sbjct: 4048 LHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIG-QCYDSS 4106 Query: 962 AHPRLPCFHGGRCVERYSY-YTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSA 1020 R PC HG C+ Y + C C F G C H+ E +R + L Sbjct: 4107 PCERQPCQHGATCMPAGEYEFQCLC-RDGFKGDLCEHE-----ENPCQLR---EPCLHGG 4157 Query: 1021 AREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDY---PRPGRPVPGYRGPVY 1077 + + L +PG+ P G G G D+ G PG G + Sbjct: 4158 TCQGTRCLC----------LPGFSGPRCQQG-SGHGIAESDWHLEGSGGNDAPGQYGAYF 4206 Query: 1078 NVTG-----------------EEVSFSFSTSSAPAVLLYVSSFV------RDYMAVLIKD 1114 + G E + TS+A +LL+ V +D++++ ++ Sbjct: 4207 HDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQ- 4265 Query: 1115 DGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVD 1174 DG L RYQLG S ++ P+ DG+ H + R R IQVD L + S + Sbjct: 4266 DGHLVFRYQLG-SGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGR-SPGPN 4323 Query: 1175 SQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNVAP 1220 +++ ++Y+G + + R+++ G +GC+ + ++ P Sbjct: 4324 VAVNAKGSVYIGGAPDVATLTG--GRFSS-GITGCVKNLVLHSARP 4366 Score = 48.5 bits (114), Expect = 4e-05 Identities = 41/136 (30%), Positives = 63/136 (46%), Gaps = 17/136 (12%) Query: 203 FKTEEKDGLLLHAEGAQG---DYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLN 259 FK DG+LL + G G D+V+L + G HL LGS G + + L Sbjct: 3957 FKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGS-------GLAVLRSAEPLA 4009 Query: 260 DQHWHYVRVDRFGRDVNFTLDGYVQRFILN---GDFERLNLDTEMFIGGLVGAARKNLA- 315 WH V +R +D + ++G R +L G + LNL T +++GG+ + + A Sbjct: 4010 LGRWHRVSAERLNKDGSLRVNG--GRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPAT 4067 Query: 316 -YRHNFRGCIENVIFN 330 +FRGC+ V N Sbjct: 4068 NMSAHFRGCVGEVSVN 4083 Score = 44.3 bits (103), Expect = 8e-04 Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 25/169 (14%) Query: 176 YFDGDDAISYRFPRGV-SRSLWDV---FAFSFKTEEKDGLLLH-----AEGAQG-DYVTL 225 YF D ++ FP V SRSL +V +T GLLL E QG D+++L Sbjct: 4205 YFHDDGFLA--FPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISL 4262 Query: 226 ELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQR 285 L+ HL+ LGS G + + +ND WH V R GR + +DG + Sbjct: 4263 GLQDGHLVFRYQLGS-------GEARLVSEDPINDGEWHRVTALREGRRGSIQVDG--EE 4313 Query: 286 FILN---GDFERLNLDTEMFIGGLVGAAR-KNLAYRHNFRGCIENVIFN 330 + G +N ++IGG A + GC++N++ + Sbjct: 4314 LVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLH 4362 Score = 37.7 bits (86), Expect = 0.077 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 7/114 (6%) Query: 385 VSFRFRTWDLTGLLLFSRL-----GDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRL 439 + RT +GLLL+ + G G + L L +G + V Q G + + + + Sbjct: 4230 IELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHL-VFRYQLGSGEARLVSEDPI 4288 Query: 440 NDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYP-LLIRTGTSYFFGGCPKPAS 492 NDG WH V + + I +D E R P + + S + GG P A+ Sbjct: 4289 NDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVAT 4342 Score = 37.4 bits (85), Expect = 0.10 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 8/73 (10%) Query: 927 FVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPR-LPCFHGGRCVE-RYSYYTCD 984 F+GC+R +R+ G + + G S HC R PC +GG+C + S Y C Sbjct: 3816 FIGCVRELRIQGEEIVFHDLNLTAHGIS-----HCPTCRDRPCQNGGQCHDSESSSYVCV 3870 Query: 985 CDLTAFDGPYCNH 997 C F G C H Sbjct: 3871 CP-AGFTGSRCEH 3882 Score = 33.1 bits (74), Expect = 1.9 Identities = 47/188 (25%), Positives = 76/188 (40%), Gaps = 27/188 (14%) Query: 790 FHTGAALRFPPIRANHSLD-----VSFYFRTSAPSGVFL-ENMGGPYCQWRRPYVRVELN 843 FH L FP + SL + RTS SG+ L + + + ++ + L Sbjct: 4206 FHDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQ 4265 Query: 844 TSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPL 903 +VF + +G+G+ L S+D ND EWH V A ++ ++VD V P Sbjct: 4266 DGH-LVFRYQLGSGEARLV--SED-PINDGEWHRVTALREGRRGSIQVDGEELVSGRSP- 4320 Query: 904 QTYIWMEYDQPLYVGS----AELKRRPF----VGCLRAMRLNGV--------TLNLEGRA 947 + + +Y+G A L F GC++ + L+ L+L+ RA Sbjct: 4321 GPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLHSARPGAPPPQPLDLQHRA 4380 Query: 948 NASEGTSP 955 A T P Sbjct: 4381 QAGANTRP 4388 >gi|239758135 PREDICTED: similar to cell recognition molecule CASPR3 [Homo sapiens] Length = 140 Score = 67.0 bits (162), Expect = 1e-10 Identities = 35/113 (30%), Positives = 68/113 (60%), Gaps = 4/113 (3%) Query: 1079 VTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTR 1136 +T E ++ SF T+ P++LLYVSSF +Y++V++ ++G+LQ+RY+L +P + + Sbjct: 28 LTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFK 87 Query: 1137 PVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVM 1189 + DGQ H + I R + V+ +++ L ++ ++ K+L LG+V+ Sbjct: 88 NMADGQLHQVKINR--EEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVL 138 >gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] Length = 909 Score = 65.9 bits (159), Expect = 3e-10 Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 8/144 (5%) Query: 31 GPLYARSLGASSYYSL-LTAPRFARLHGI-SGWSPRIGDPNPWLQIDLMKKHRIRAVATQ 88 G + + ASS YS P+ +RLHG +GW+P + +LQ+DL + A+ATQ Sbjct: 286 GRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQ 345 Query: 89 GSFN----SWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTAR 144 G+ + + +V Y L + W + ++ F N + + VV + LH R Sbjct: 346 GAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTR 405 Query: 145 YIRIVPLAWNPRGKIGLRLGLYGC 168 ++RI P W+ I LRL L+GC Sbjct: 406 FVRIRPQTWH--SGIALRLELFGC 427 Score = 52.0 bits (123), Expect = 4e-06 Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 20/158 (12%) Query: 29 LVGPLYARSLGASSYYSLLTAPRFARL-HGISGWSPRIGDPNP---WLQIDLMKKHRIRA 84 L G + + ASS L +P ARL SGW PRI P WLQ+DL ++ Sbjct: 441 LSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKG 500 Query: 85 VATQGS--------FNSWDWVTRYMLLYGDRVDSWTPFY--QRGHNSTFFGNVNESA--V 132 V QG+ + +V ++ + Y W + F GN++ + Sbjct: 501 VIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDI 560 Query: 133 VRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPY 170 R D A+Y+R+ P W+P G IG+RL + GC + Sbjct: 561 RRFD---PIPAQYVRVYPERWSPAG-IGMRLEVLGCDW 594 >gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] Length = 901 Score = 65.9 bits (159), Expect = 3e-10 Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 8/144 (5%) Query: 31 GPLYARSLGASSYYSL-LTAPRFARLHGI-SGWSPRIGDPNPWLQIDLMKKHRIRAVATQ 88 G + + ASS YS P+ +RLHG +GW+P + +LQ+DL + A+ATQ Sbjct: 286 GRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQ 345 Query: 89 GSFN----SWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTAR 144 G+ + + +V Y L + W + ++ F N + + VV + LH R Sbjct: 346 GAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTR 405 Query: 145 YIRIVPLAWNPRGKIGLRLGLYGC 168 ++RI P W+ I LRL L+GC Sbjct: 406 FVRIRPQTWH--SGIALRLELFGC 427 Score = 52.0 bits (123), Expect = 4e-06 Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 20/158 (12%) Query: 29 LVGPLYARSLGASSYYSLLTAPRFARL-HGISGWSPRIGDPNP---WLQIDLMKKHRIRA 84 L G + + ASS L +P ARL SGW PRI P WLQ+DL ++ Sbjct: 441 LSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKG 500 Query: 85 VATQGS--------FNSWDWVTRYMLLYGDRVDSWTPFY--QRGHNSTFFGNVNESA--V 132 V QG+ + +V ++ + Y W + F GN++ + Sbjct: 501 VIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDI 560 Query: 133 VRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPY 170 R D A+Y+R+ P W+P G IG+RL + GC + Sbjct: 561 RRFD---PIPAQYVRVYPERWSPAG-IGMRLEVLGCDW 594 >gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] Length = 931 Score = 65.9 bits (159), Expect = 3e-10 Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 8/144 (5%) Query: 31 GPLYARSLGASSYYSL-LTAPRFARLHGI-SGWSPRIGDPNPWLQIDLMKKHRIRAVATQ 88 G + + ASS YS P+ +RLHG +GW+P + +LQ+DL + A+ATQ Sbjct: 286 GRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQ 345 Query: 89 GSFN----SWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTAR 144 G+ + + +V Y L + W + ++ F N + + VV + LH R Sbjct: 346 GAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTR 405 Query: 145 YIRIVPLAWNPRGKIGLRLGLYGC 168 ++RI P W+ I LRL L+GC Sbjct: 406 FVRIRPQTWH--SGIALRLELFGC 427 Score = 52.0 bits (123), Expect = 4e-06 Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 20/158 (12%) Query: 29 LVGPLYARSLGASSYYSLLTAPRFARL-HGISGWSPRIGDPNP---WLQIDLMKKHRIRA 84 L G + + ASS L +P ARL SGW PRI P WLQ+DL ++ Sbjct: 441 LSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKG 500 Query: 85 VATQGS--------FNSWDWVTRYMLLYGDRVDSWTPFY--QRGHNSTFFGNVNESA--V 132 V QG+ + +V ++ + Y W + F GN++ + Sbjct: 501 VIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDI 560 Query: 133 VRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPY 170 R D A+Y+R+ P W+P G IG+RL + GC + Sbjct: 561 RRFD---PIPAQYVRVYPERWSPAG-IGMRLEVLGCDW 594 >gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] Length = 555 Score = 65.9 bits (159), Expect = 3e-10 Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 8/144 (5%) Query: 31 GPLYARSLGASSYYSL-LTAPRFARLHGI-SGWSPRIGDPNPWLQIDLMKKHRIRAVATQ 88 G + + ASS YS P+ +RLHG +GW+P + +LQ+DL + A+ATQ Sbjct: 286 GRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQ 345 Query: 89 GSFN----SWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTAR 144 G+ + + +V Y L + W + ++ F N + + VV + LH R Sbjct: 346 GAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTR 405 Query: 145 YIRIVPLAWNPRGKIGLRLGLYGC 168 ++RI P W+ I LRL L+GC Sbjct: 406 FVRIRPQTWH--SGIALRLELFGC 427 Score = 37.7 bits (86), Expect = 0.077 Identities = 25/66 (37%), Positives = 32/66 (48%), Gaps = 4/66 (6%) Query: 29 LVGPLYARSLGASSYYSLLTAPRFARL-HGISGWSPRIGDPNP---WLQIDLMKKHRIRA 84 L G + + ASS L +P ARL SGW PRI P WLQ+DL ++ Sbjct: 441 LSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKG 500 Query: 85 VATQGS 90 V QG+ Sbjct: 501 VIIQGA 506 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.140 0.459 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 60,838,427 Number of Sequences: 37866 Number of extensions: 3243804 Number of successful extensions: 30011 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 343 Number of HSP's successfully gapped in prelim test: 401 Number of HSP's that attempted gapping in prelim test: 18853 Number of HSP's gapped (non-prelim): 8197 length of query: 1384 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1269 effective length of database: 13,892,928 effective search space: 17630125632 effective search space used: 17630125632 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.