Guide to the Human Genome
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Search of human proteins with 4505463

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505463 contactin associated protein 1 precursor [Homo
sapiens]
         (1384 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505463 contactin associated protein 1 precursor [Homo sapiens]   2930   0.0  
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi...  1145   0.0  
gi|18640734 contactin associated protein-like 5 [Homo sapiens]        938   0.0  
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap...   931   0.0  
gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1...   884   0.0  
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap...   882   0.0  
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]           879   0.0  
gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2...   708   0.0  
gi|239743797 PREDICTED: similar to cell recognition molecule CAS...   344   4e-94
gi|239743729 PREDICTED: similar to contactin associated protein-...   246   1e-64
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]        134   8e-31
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]       133   1e-30
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]       131   5e-30
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]       130   7e-30
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]             115   3e-25
gi|169184330 PREDICTED: novel protein similar to contactin assoc...   103   1e-21
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ...    74   7e-13
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...    72   4e-12
gi|38788416 laminin, alpha 1 precursor [Homo sapiens]                  70   1e-11
gi|10518506 coagulation factor VIII isoform b precursor [Homo sa...    70   1e-11
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap...    70   1e-11
gi|105990535 coagulation factor V precursor [Homo sapiens]             69   4e-11
gi|10835083 X-linked juvenile retinoschisis protein precursor [H...    69   4e-11
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap...    68   5e-11
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             68   7e-11
gi|239758135 PREDICTED: similar to cell recognition molecule CAS...    67   1e-10
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]            66   3e-10
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]            66   3e-10
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]            66   3e-10
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]            66   3e-10

>gi|4505463 contactin associated protein 1 precursor [Homo sapiens]
          Length = 1384

 Score = 2930 bits (7597), Expect = 0.0
 Identities = 1384/1384 (100%), Positives = 1384/1384 (100%)

Query: 1    MMHLRLFCILLAAVSGAEGWGYYGCDEELVGPLYARSLGASSYYSLLTAPRFARLHGISG 60
            MMHLRLFCILLAAVSGAEGWGYYGCDEELVGPLYARSLGASSYYSLLTAPRFARLHGISG
Sbjct: 1    MMHLRLFCILLAAVSGAEGWGYYGCDEELVGPLYARSLGASSYYSLLTAPRFARLHGISG 60

Query: 61   WSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHN 120
            WSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHN
Sbjct: 61   WSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHN 120

Query: 121  STFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGD 180
            STFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGD
Sbjct: 121  STFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGD 180

Query: 181  DAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGS 240
            DAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGS
Sbjct: 181  DAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGS 240

Query: 241  SPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTE 300
            SPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTE
Sbjct: 241  SPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTE 300

Query: 301  MFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVP 360
            MFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVP
Sbjct: 301  MFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVP 360

Query: 361  HPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVN 420
            HPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVN
Sbjct: 361  HPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVN 420

Query: 421  VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGT 480
            VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGT
Sbjct: 421  VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGT 480

Query: 481  SYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGI 540
            SYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGI
Sbjct: 481  SYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGI 540

Query: 541  TDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTI 600
            TDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTI
Sbjct: 541  TDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTI 600

Query: 601  DPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVS 660
            DPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVS
Sbjct: 601  DPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVS 660

Query: 661  ALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLD 720
            ALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLD
Sbjct: 661  ALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLD 720

Query: 721  RSCVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYG 780
            RSCVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYG
Sbjct: 721  RSCVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYG 780

Query: 781  DRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRV 840
            DRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRV
Sbjct: 781  DRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRV 840

Query: 841  ELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRP 900
            ELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRP
Sbjct: 841  ELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRP 900

Query: 901  MPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGH 960
            MPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGH
Sbjct: 901  MPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGH 960

Query: 961  CAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSA 1020
            CAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSA
Sbjct: 961  CAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSA 1020

Query: 1021 AREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVT 1080
            AREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVT
Sbjct: 1021 AREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVT 1080

Query: 1081 GEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTD 1140
            GEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTD
Sbjct: 1081 GEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTD 1140

Query: 1141 GQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQR 1200
            GQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQR
Sbjct: 1141 GQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQR 1200

Query: 1201 YNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEV 1260
            YNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEV
Sbjct: 1201 YNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEV 1260

Query: 1261 PPELDPWYLPPDFPYYHDEGWVAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEP 1320
            PPELDPWYLPPDFPYYHDEGWVAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEP
Sbjct: 1261 PPELDPWYLPPDFPYYHDEGWVAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEP 1320

Query: 1321 KAAHEYHPGSKPPLPTSGPAQVPTPTAAPNQAPASAPAPAPTPAPAPGPRDQNLPQILEE 1380
            KAAHEYHPGSKPPLPTSGPAQVPTPTAAPNQAPASAPAPAPTPAPAPGPRDQNLPQILEE
Sbjct: 1321 KAAHEYHPGSKPPLPTSGPAQVPTPTAAPNQAPASAPAPAPTPAPAPGPRDQNLPQILEE 1380

Query: 1381 SRSE 1384
            SRSE
Sbjct: 1381 SRSE 1384


>gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapiens]
          Length = 1331

 Score = 1145 bits (2961), Expect = 0.0
 Identities = 577/1321 (43%), Positives = 824/1321 (62%), Gaps = 76/1321 (5%)

Query: 25   CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81
            CDE LV  L   +  +SS  S   +P +A+++   G  GWSP   D   WLQ+D   + +
Sbjct: 35   CDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQ 94

Query: 82   IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141
            I A+ATQG ++S DWVT+Y +LY D   +W P++Q G+   F GN+N   VVRH+L    
Sbjct: 95   ISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPI 154

Query: 142  TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201
             ARY+RIVPL WN  G+IGLR+ +YGC Y AD++ FDG   + YRF     ++L DV A 
Sbjct: 155  IARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIAL 214

Query: 202  SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261
            +FKT E +G++LH EG QGDY+TLEL+ A L+L ++LGS+ + P  GHT+V  G +L+D 
Sbjct: 215  NFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274

Query: 262  HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321
            HWH V ++R GR +N TLD  +Q F  NG+F+ L+LD E+  GG+  + + + + R NF+
Sbjct: 275  HWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFK 334

Query: 322  GCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRG 381
            GC+E++ +N VNI DLA R+    +  G ++F C++P   P+ F    ++++VPG   + 
Sbjct: 335  GCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVFFNAT-SYLEVPGRLNQD 393

Query: 382  RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQ--VNVSIAQSGRKKLQFAAGYRL 439
              +VSF+FRTW+  GLL+FS   D LG+VE+ L+E +  V+++I Q+   ++  ++G  L
Sbjct: 394  LFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGL 453

Query: 440  NDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSN 499
            NDG WHEV F+A+EN A+++ID  E + VR + PL ++TG  YFFGG     +       
Sbjct: 454  NDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVL 513

Query: 500  QTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSW 559
            Q +F GCM+L++VD QLVNL  V  R+ G +A V  D C I DRC PN CEH G+C Q+W
Sbjct: 514  QPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTW 573

Query: 560  DDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRE 619
            D F C C+ TGY G TCH  +Y+ SCEAY+  G+TS  + IDPDGSGPL P  VYC++ E
Sbjct: 574  DSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTE 633

Query: 620  NRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYN 679
            ++ WT+V HD    T V G + E+  +  + Y +AS +++SA+ +++++CEQ++ + C  
Sbjct: 634  DKVWTIVSHDLQMQTPVVGYNPEKYSVTQLVY-SASMDQISAITDSAEYCEQYVSYFCKM 692

Query: 680  SRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQW 739
            SRLLNT  G PY++W+G+  E+H+YWGGS PGIQ+CACG++R+C DP  YCNCDAD  QW
Sbjct: 693  SRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQW 752

Query: 740  RTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISF-HTGAALRF 798
            R D G L++ DHLPV+QVV+GDT+R  SEA+  + PLRC GDRN WN  SF +  + L F
Sbjct: 753  RKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHF 812

Query: 799  PPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGD 858
               +   S D+SFYF+T  P GVFLENMG      +  ++++EL ++ +V F+FDVGNG 
Sbjct: 813  STFQGETSADISFYFKTLTPWGVFLENMG------KEDFIKLELKSATEVSFSFDVGNGP 866

Query: 859  ENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVG 918
              + V S     NDD+WH V AE NVKQA L+VD  P  +R  P + +  +E    L+VG
Sbjct: 867  VEIVVRSPT-PLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVG 925

Query: 919  SAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERY 978
             A   ++ F+GC+R++R+NGVTL+LE RA  + G    C+GHC      C +GG+C+ERY
Sbjct: 926  GAG-GQQGFLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERY 984

Query: 979  SYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPG 1038
              Y+CDC  TA+DG +CN D+G FFE G W+RYN Q+   +A    S + + P       
Sbjct: 985  HGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAP------- 1037

Query: 1039 YIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLL 1098
                 D     P                           ++  EE+ FSFST+ AP +LL
Sbjct: 1038 -----DQQNSHP---------------------------DLAQEEIRFSFSTTKAPCILL 1065

Query: 1099 YVSSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLF 1156
            Y+SSF  D++AVL+K  G+LQ+RY LG    PY   +  R + +GQPHS+NITR  + +F
Sbjct: 1066 YISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIF 1125

Query: 1157 IQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFN 1216
            +++D++P          D+  +SPK+L+LG+V+ETG ID EI +YNTPGF+GCLS V+FN
Sbjct: 1126 LKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQFN 1185

Query: 1217 NVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEVPPELDPWYL------P 1270
             +APLK   R         +  + +QGEL ESNCGA P  +S +    DPW+L       
Sbjct: 1186 QIAPLKAALR-----QTNASAHVHIQGELVESNCGASPLTLSPMSSATDPWHLDHLDSAS 1240

Query: 1271 PDFPYYHDEGWV--------AILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEPKA 1322
             DFPY   +G          + ++G ++A ++  ++  LV       R+KG+YHTNE K 
Sbjct: 1241 ADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKG 1300

Query: 1323 A 1323
            A
Sbjct: 1301 A 1301


>gi|18640734 contactin associated protein-like 5 [Homo sapiens]
          Length = 1306

 Score =  938 bits (2424), Expect = 0.0
 Identities = 510/1340 (38%), Positives = 761/1340 (56%), Gaps = 93/1340 (6%)

Query: 5    RLFCILLAAVSGAEGWGY----YGCDEELVGPLYARSLGASSYYSLLTAPRFARLH---G 57
            RL  +L    SG    G     Y CD+ L   L   +  +SS  +   +P  A+L+   G
Sbjct: 6    RLTSVLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVG 63

Query: 58   ISGWSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQR 117
              GWSP   +   WLQ+DL  +  I AVATQG + S DWVT Y L++ D   +W  + Q 
Sbjct: 64   TGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQE 123

Query: 118  GHNSTFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYF 177
                TF GN+N  +VV H L     AR++R VPL WNP GKIG+R+ +YGC YK+D+  F
Sbjct: 124  DSIWTFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADF 183

Query: 178  DGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMS 237
            DG  ++ YRF + +  +L DV +  FK+ + DG+L H EG +GD++TLEL+   L LH++
Sbjct: 184  DGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLN 243

Query: 238  LGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNL 297
            LG S  +      + + G +L+DQHWH V ++R G+ VNFT+D + Q F   G+ + L++
Sbjct: 244  LGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDI 303

Query: 298  DTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLD 357
            D E+  GG+    +     + NF GCIEN+ +N VNI DLA RR  +I + G V F C +
Sbjct: 304  DYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQI-YTGNVTFSCSE 362

Query: 358  PVPHPINF-GGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSE 416
            P   PI F     +++ +PG P+   L+VSF+FRTW+  GLLL + L +G G + L+L  
Sbjct: 363  PQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEG 422

Query: 417  GQVNVSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLI 476
            G + + I +   +  +   G  LNDG WH V+  A+ N   +++DD        S  + I
Sbjct: 423  GILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQI 482

Query: 477  RTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFD 536
             +G SY+FGGCP   +   C +   AF GCM L+ +D Q  +L  V+   LG ++++  D
Sbjct: 483  YSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHID 542

Query: 537  TCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSG 596
             C I DRC PN CEH G C QSW  F C C  T Y G TCH  +Y++SCE YR  G T+G
Sbjct: 543  LCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAG 602

Query: 597  NFTIDPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASW 656
             F ID DGSGPL P  VYC+I E++ WT V+H+    TRV G++ E+P+  A+ Y   S 
Sbjct: 603  FFYIDSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDY-GGSM 661

Query: 657  EEVSALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCA 716
            E++ A+ + S+HCEQ + + C  SRLLNT  G P+++WIGR+ E+H YWGGS PG+Q+C 
Sbjct: 662  EQLEAVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCE 721

Query: 717  CGLDRSCVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPL 776
            CGLD SC+D   +CNCDAD+ +W  D G L+F DHLPVTQ+VI DT+RS SEA + + PL
Sbjct: 722  CGLDESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPL 781

Query: 777  RCYGDRNSWNTISFHTGAA-LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRR 835
            RCYGDR  WN +SF+T A+ L FP   A  S D+SF+F+T+A SGVFLEN+G       +
Sbjct: 782  RCYGDRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLG------IK 835

Query: 836  PYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRP 895
             ++R+E+++  ++ FA DVGNG   L V S     ND++WH VRAE N+K+  L+VD+ P
Sbjct: 836  DFIRLEISSPSEITFAIDVGNGPVELVVQSPSL-LNDNQWHYVRAERNLKETSLQVDNLP 894

Query: 896  WVLRPMPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSP 955
               R    + +  ++ +  L+VG    +++ F+GC+R++ LNG  ++LE RA  + G  P
Sbjct: 895  RSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRP 954

Query: 956  NCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQS 1015
             C GHC+     C +GG+CVE+++ Y CDC  + ++GP+C  ++   FE GT + Y  Q 
Sbjct: 955  GCPGHCSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQE 1014

Query: 1016 ---ALRSAAREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGY 1072
                 ++ +   S + +   P  E                                    
Sbjct: 1015 PYPVTKNISLSSSAIYTDSAPSKE------------------------------------ 1038

Query: 1073 RGPVYNVTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLG-TSPYVY 1131
                       ++ SF T+ AP++LL+++S  +D++ VL+  +G+LQ+RY L     +V+
Sbjct: 1039 ----------NIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEETHVF 1088

Query: 1132 QLTTRPVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMET 1191
             +      + + H + I R  R L IQ+D        FS  V+ ++   ++L LG+V E 
Sbjct: 1089 TIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRV--IRSLTLGKVTEN 1146

Query: 1192 GVIDPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFR--TPRPMTAELAEALRVQGELSESN 1249
              +D E+ + N  GF+GC+S V++N++APLK   R  T  P+T        V G L+ES+
Sbjct: 1147 LGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVT--------VHGTLTESS 1198

Query: 1250 CGAM----PRLVSEVPPELDPWYLPPD-FPYYHDEGWVAILLGFLVA---FLLLGLVGML 1301
            CG M       V+ V    DP+    +  P  +     + ++G ++A   F++  ++G++
Sbjct: 1199 CGFMVDSDVNAVTTVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIM 1258

Query: 1302 VLFYLQNHRYKGSYHTNEPK 1321
              F  Q   +K S+ T++ K
Sbjct: 1259 TRFLYQ---HKQSHRTSQMK 1275


>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sapiens]
          Length = 1308

 Score =  931 bits (2406), Expect = 0.0
 Identities = 478/1244 (38%), Positives = 722/1244 (58%), Gaps = 68/1244 (5%)

Query: 18   EGWGYYGCDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQI 74
            E    Y CD+ LV  L   S  +SS  S    P FARL+   G  GWSP + +   WLQI
Sbjct: 24   EAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQI 83

Query: 75   DLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVR 134
            DL ++  + AVATQG + S +WVT Y+L++ D   +W  + Q      F GN N  +VV 
Sbjct: 84   DLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVY 143

Query: 135  HDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRS 194
            + L     AR++R +PL WNP+G+IG+R+ ++GC Y+++++  DG  ++ YRF +     
Sbjct: 144  YRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSP 203

Query: 195  LWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSA 254
            + D+ +  FKT + DG+LLH EG  GD++TL+L  A L L ++ G + +        ++ 
Sbjct: 204  IKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTL 263

Query: 255  GGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNL 314
            G +L+DQHWH V + R G+ VNFT+D +   F   G+F  +NLD E+  GG + A  K++
Sbjct: 264  GSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEISFGG-IPAPGKSV 322

Query: 315  AYRH-NFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQ 373
            ++ H NF GC+EN+ +N V+I DLA ++  +I   G V+F C  P   P+ F    +++ 
Sbjct: 323  SFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSSRSYLA 382

Query: 374  VPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQF 433
            +P F     ++ +F+FRTW+  GLLLFS L    G + L LS+G++  ++ Q G+     
Sbjct: 383  LPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDI 442

Query: 434  AAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASR 493
             AG  LNDG WH V+  A++NH  +++D    +   +  P  I +G +Y+FGGCP  +  
Sbjct: 443  TAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFG 502

Query: 494  WDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDG 553
              C S    F GCM L+ + G++V+L  V+   LG ++++  D+CGI+DRC PN CEH G
Sbjct: 503  SKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGG 562

Query: 554  RCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVV 613
             C QSW  F C C  TGY+G TCH  +Y++SCEAY+  G TSG + ID DGSGPL+PF++
Sbjct: 563  ECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLL 622

Query: 614  YCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWI 673
            YC++ E  AWT+++H+    TRV  ++ E P+ G  +Y  AS E++ A  N ++HCEQ  
Sbjct: 623  YCNMTET-AWTIIQHNGSDLTRVRNTNPENPYAGFFEYV-ASMEQLQATINRAEHCEQEF 680

Query: 674  EFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCD 733
             + C  SRL+N   G P S+W+GR  E   YWGGS P +Q+C CGL+ +C+D   YCNCD
Sbjct: 681  TYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCD 740

Query: 734  ADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTG 793
            AD+ +W  D GLL + +HLPVT++VI DT R  SEA + L PL C GDR+ WN+ SF T 
Sbjct: 741  ADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTE 800

Query: 794  AA-LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAF 852
            A+ L FP      S DVSF+F+T+A SGVFLEN+G         ++R+EL +   V F+F
Sbjct: 801  ASYLHFPTFHGELSADVSFFFKTTASSGVFLENLG------IADFIRIELRSPTVVTFSF 854

Query: 853  DVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYD 912
            DVGNG   ++V S    FND++WH VR E N+K+A L+VD      +P P   ++ ++ +
Sbjct: 855  DVGNGPFEISVQSPT-HFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLN 913

Query: 913  QPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGG 972
              L+VG    ++R F+GC+R+++LNG+TL+LE RA  +    P C GHC+     C +GG
Sbjct: 914  SQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGG 973

Query: 973  RCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPV 1032
            +C ER   + CDC  +A+ GP+C+++I  +F  G+ + YN Q                  
Sbjct: 974  KCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQE----------------- 1016

Query: 1033 PGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSS 1092
                  Y+   ++  +   +HG                        ++ E + FSF T+ 
Sbjct: 1017 -----NYLLSKNSSSHAASFHGD---------------------MKLSREMIKFSFRTTR 1050

Query: 1093 APAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITR 1150
             P++LL+VSSF ++Y++V+I  +G+LQ+RY+L     P V     + + DGQ H I I R
Sbjct: 1051 TPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINR 1110

Query: 1151 VYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCL 1210
                +FI++D      ++  L   ++  + K+L LGR++E   +D +       GF+GCL
Sbjct: 1111 EEGVVFIEID--DNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCL 1168

Query: 1211 SGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMP 1254
            S V+ ++VAPLK       P      + + V G ++ES+C A P
Sbjct: 1169 SAVQLSHVAPLKAALHPSHP------DPVTVTGHVTESSCMAQP 1206


>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
            [Homo sapiens]
          Length = 1288

 Score =  884 bits (2284), Expect = 0.0
 Identities = 455/1212 (37%), Positives = 690/1212 (56%), Gaps = 60/1212 (4%)

Query: 25   CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81
            CD  L   L   S  +SS  S    P F+RL+   G  GW+P + +   WLQIDL ++  
Sbjct: 31   CDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90

Query: 82   IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141
            + AVATQG + S DWVT Y+L++ D   +W  + +      F GN N  +VV + L   F
Sbjct: 91   VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150

Query: 142  TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201
             AR++R +PLAWNPRG+IG+R+ +YGC YK++++YFDG  A+ Y   +   + + DV + 
Sbjct: 151  EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210

Query: 202  SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261
             FK  + +G+LLH EG  G+++TLEL    L+  ++ G++ +       T++ G +L+DQ
Sbjct: 211  KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270

Query: 262  HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321
            HWH V ++     VNFT+D +   F   GD   L+L+ E+  GG++   R     R +F 
Sbjct: 271  HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFH 330

Query: 322  GCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRG 381
            GC+EN+ +N V++ +LA +   +I   G V+F C  P   P+ F    +++ +PG     
Sbjct: 331  GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390

Query: 382  RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLND 441
            +++V+F+FRTW+  G LLF  L  G G   L L +G++ +S+ Q+G+      AG  LND
Sbjct: 391  KVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLND 450

Query: 442  GFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQT 501
            G WH V+F A+ +H  + +DD    +  V+  +LI +G +Y+FGGC   +S   C S   
Sbjct: 451  GQWHSVSFSAKWSHMNVVVDDDTAVQPLVA--VLIDSGDTYYFGGCLGNSSGSGCKSPLG 508

Query: 502  AFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDD 561
             F GC+ L+ +  + V+  LV+   LG + ++  D+CGITDRC P+ CEH G C QSWD 
Sbjct: 509  GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 568

Query: 562  FICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRENR 621
            F C C  TGY GETCH+ LY++SCEA++  G  SG + ID DGSGPL PF+VYC++  + 
Sbjct: 569  FSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTADS 628

Query: 622  AWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSR 681
            AWTVVRH       + G+    P       + A   ++ A  N ++ CEQ +   C  +R
Sbjct: 629  AWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGTAR 688

Query: 682  LLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRT 741
              ++  G P S+W+GR  E H  WGGS P  Q+C CGL+ +C+D   YCNCDA Q +W +
Sbjct: 689  RPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTS 748

Query: 742  DKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPP 800
            D  +L+  +HLPVTQ+V+ DT +  SEA + L PL C GD++ WN+ SF+T  + L FP 
Sbjct: 749  DTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPA 808

Query: 801  IRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDEN 860
                 + DV F+F+T+  SGVF+EN+G         ++R+EL    +V F+FDVGNG   
Sbjct: 809  FHGELTADVCFFFKTTVSSGVFMENLG------ITDFIRIELRAPTEVTFSFDVGNGPCE 862

Query: 861  LTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSA 920
            +TV S    FND++WH VRAE NVK A L+VD  P  ++P P   ++ ++ +  L++G  
Sbjct: 863  VTVQSPT-PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT 921

Query: 921  ELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSY 980
              ++R F+GC+R+++LNGV L+LE RA  + G  P C GHC+     C +GGRC E+   
Sbjct: 922  ATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRG 981

Query: 981  YTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYI 1040
             TCDC  +A+DGP+C+++I  +F  G+ M Y+ Q     +    S + S           
Sbjct: 982  VTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSL---------- 1031

Query: 1041 PGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYV 1100
                                           YR     +T E ++ SF T+ +P++LLYV
Sbjct: 1032 -------------------------------YRD--VTLTREMITLSFRTTRSPSLLLYV 1058

Query: 1101 SSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQ 1158
            SSF  +Y++V++ ++G+LQ+RY+L    +P  +    + + DGQ H + I R      + 
Sbjct: 1059 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINR--EEAVVM 1116

Query: 1159 VDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNV 1218
            V+     +++  L   ++ ++ K+L LG+V+E    DP+ +R  T GF+GCLS VRF   
Sbjct: 1117 VEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRA 1176

Query: 1219 APLKTHFRTPRP 1230
            APLK   R   P
Sbjct: 1177 APLKAALRPSGP 1188


>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sapiens]
          Length = 1235

 Score =  882 bits (2278), Expect = 0.0
 Identities = 459/1238 (37%), Positives = 691/1238 (55%), Gaps = 114/1238 (9%)

Query: 23   YGCDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKK 79
            Y CD+ LV  L   S  +SS  S    P FARL+   G  GWSP + +   WLQIDL ++
Sbjct: 4    YDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGER 63

Query: 80   HRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHF 139
              + AVATQG + S +WVT Y+L++ D   +W  + Q      F GN N  +VV + L  
Sbjct: 64   MEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQP 123

Query: 140  HFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVF 199
               AR++R +PL WNP+G+IG+R+ ++GC Y+++++  DG  ++ YRF +     + D+ 
Sbjct: 124  SIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDII 183

Query: 200  AFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLN 259
            +  FKT + DG+LLH EG  GD++TL+L  A L L ++ G + +        ++ G +L+
Sbjct: 184  SLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLD 243

Query: 260  DQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHN 319
            DQHWH V + R G+ VNFT+D +   F   G+F  +NLD                     
Sbjct: 244  DQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLD--------------------- 282

Query: 320  FRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPR 379
                                       +EG V+F C  P   P+ F    +++ +P F  
Sbjct: 283  ---------------------------YEGNVSFSCSQPQSMPVTFLSSRSYLALPDFSG 315

Query: 380  RGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRL 439
               ++ +F+FRTW+  GLLLFS L    G + L LS+G++  ++ Q G+      AG  L
Sbjct: 316  EEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVEL 375

Query: 440  NDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSN 499
            NDG WH V+  A++NH  +++D    +   +  P  I +G +Y+FGGCP  +    C S 
Sbjct: 376  NDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSP 435

Query: 500  QTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSW 559
               F GCM L+ + G++V+L  V+   LG ++++  D+CGI+DRC PN CEH G C QSW
Sbjct: 436  LGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSW 495

Query: 560  DDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRE 619
              F C C  TGY+G TCH  +Y++SCEAY+  G TSG + ID DGSGPL+PF++YC++ E
Sbjct: 496  STFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMTE 555

Query: 620  NRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYN 679
              AWT+++H+    TRV  ++ E P+ G  +Y  AS E++ A  N ++HCEQ   + C  
Sbjct: 556  T-AWTIIQHNGSDLTRVRNTNPENPYAGFFEYV-ASMEQLQATINRAEHCEQEFTYYCKK 613

Query: 680  SRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQW 739
            SRL+N   G P S+W+GR  E   YWGGS P +Q+C CGL+ +C+D   YCNCDAD+ +W
Sbjct: 614  SRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEW 673

Query: 740  RTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRF 798
              D GLL + +HLPVT++VI DT R  SEA + L PL C GDR+ WN+ SF T A+ L F
Sbjct: 674  TNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHF 733

Query: 799  PPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGD 858
            P      S DVSF+F+T+A SGVFLEN+G         ++R+EL +   V F+FDVGNG 
Sbjct: 734  PTFHGELSADVSFFFKTTASSGVFLENLG------IADFIRIELRSPTVVTFSFDVGNGP 787

Query: 859  ENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVG 918
              ++V S    FND++WH VR E N+K+A L+VD      +P P   ++ ++ +  L+VG
Sbjct: 788  FEISVQSPT-HFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVG 846

Query: 919  SAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERY 978
                ++R F+GC+R+++LNG+TL+LE RA  +    P C GHC+     C +GG+C ER 
Sbjct: 847  GTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERP 906

Query: 979  SYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPG 1038
              + CDC  +A+ GP+C+++I  +F  G+ + YN Q                        
Sbjct: 907  IGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQE----------------------N 944

Query: 1039 YIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLL 1098
            Y+   ++  +   +HG                        ++ E + FSF T+  P++LL
Sbjct: 945  YLLSKNSSSHAASFHGD---------------------MKLSREMIKFSFRTTRTPSLLL 983

Query: 1099 YVSSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLF 1156
            +VSSF ++Y++V+I  +G+LQ+RY+L     P V     + + DGQ H I I R    +F
Sbjct: 984  FVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVF 1043

Query: 1157 IQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFN 1216
            I++D      ++  L   ++  + K+L LGR++E   +D +       GF+GCLS V+ +
Sbjct: 1044 IEID--DNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLS 1101

Query: 1217 NVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMP 1254
            +VAPLK       P      + + V G ++ES+C A P
Sbjct: 1102 HVAPLKAALHPSHP------DPVTVTGHVTESSCMAQP 1133


>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
          Length = 1288

 Score =  879 bits (2270), Expect = 0.0
 Identities = 455/1212 (37%), Positives = 689/1212 (56%), Gaps = 60/1212 (4%)

Query: 25   CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81
            CD  L   L   S  +SS  S    P F+RL+   G  GW+P + +   WLQIDL ++  
Sbjct: 31   CDAPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90

Query: 82   IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141
            + AVATQG + S DWVT Y+L++ D   +W  + +      F GN N  +VV + L   F
Sbjct: 91   VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150

Query: 142  TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201
             AR++R +PLAWNPRG+IG+R+ +YGC YK++++YFDG  A+ YR  +   + + DV + 
Sbjct: 151  EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYRLDKKPLKPIRDVISL 210

Query: 202  SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261
             FK  + +G+LLH EG  G+++TLEL    L+  ++ G++ +       T++ G +L+DQ
Sbjct: 211  KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270

Query: 262  HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321
            HWH V ++     VNFT+D +   F   GD   L+L+ E+  GG+    R     R +F 
Sbjct: 271  HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSYLDLNFEISFGGIPTPGRSRAFRRKSFH 330

Query: 322  GCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRG 381
            GC+EN+ +N V++ +LA +   +I   G V+F C  P   P+ F    +++ +PG     
Sbjct: 331  GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390

Query: 382  RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLND 441
            +++V+F+FRTW+  G LLF  L  G G   L L +G++ +S+ Q G+      AG  LND
Sbjct: 391  KVSVTFQFRTWNRAGHLLFGELRRGSGSFVLFLKDGKLKLSLFQPGQSPRNVTAGAGLND 450

Query: 442  GFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQT 501
            G WH V+F A+ +H  + +DD    +  V+  +LI +G +Y+FGGC   +S   C S   
Sbjct: 451  GQWHSVSFSAKWSHMNVVVDDDTAVQPLVA--VLIDSGDTYYFGGCLDNSSGSGCKSPLG 508

Query: 502  AFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDD 561
             F GC+ L+ +  + V+  LV+   LG + ++  D+CGITDRC P+ CEH G C QSWD 
Sbjct: 509  GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 568

Query: 562  FICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRENR 621
            F C C  TGY GETCH+ LY++SCEA++  G  SG + ID DGSGPL PF+VYC++  + 
Sbjct: 569  FSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTADA 628

Query: 622  AWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSR 681
            AWTVV+H       + G+    P       + A   ++ +  N ++ CEQ +   C  +R
Sbjct: 629  AWTVVQHGGPDAVTLRGAPSGHPRSAVSFAYAAGAGQLRSAVNLAERCEQRLALRCGTAR 688

Query: 682  LLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRT 741
              ++  G P S+W+GR  E H  WGGS P  Q+C CGL+ +C+D   YCNCDA + +W +
Sbjct: 689  RPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTS 748

Query: 742  DKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPP 800
            D  +L+  +HLPVTQ+V+ D  R  SEA + L PL C GD++ WN+ SF+T  + L FP 
Sbjct: 749  DTIVLSQKEHLPVTQIVMTDAGRPHSEAAYTLGPLLCRGDQSFWNSASFNTETSYLHFPA 808

Query: 801  IRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDEN 860
                 + DV F+F+T+  SGVF+EN+G         ++R+EL    +V F+FDVGNG   
Sbjct: 809  FHGELTADVCFFFKTTVSSGVFMENLG------ITDFIRIELRAPTEVTFSFDVGNGPCE 862

Query: 861  LTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSA 920
            +TV S    FND++WH VRAE NVK A L+VD  P  ++P P   ++ ++ +  L++G  
Sbjct: 863  VTVQSPT-PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT 921

Query: 921  ELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSY 980
              ++R F+GC+R+++LNGV L+LE RA  + G  P C GHC+     C +GGRC E+   
Sbjct: 922  ATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRG 981

Query: 981  YTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYI 1040
             TCDC  +A+DGP+C+++I  +F  G+ M Y+ Q                        Y 
Sbjct: 982  VTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQE----------------------HYT 1019

Query: 1041 PGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYV 1100
               ++   V   H             R V         +T E ++ SF T+  P++LLYV
Sbjct: 1020 LSENSSSLVSSLH-------------RDV--------TLTREMITLSFRTTRTPSLLLYV 1058

Query: 1101 SSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQ 1158
            SSF  +Y++V++ ++G+LQ+RY+L    +P  +    + + DGQ H + I R      + 
Sbjct: 1059 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINR--EEAVVM 1116

Query: 1159 VDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNV 1218
            V+    T+++  L   ++ ++ K+L LG+V+E    DP+ +R  T GF+GCLS VRF   
Sbjct: 1117 VEVNQSTKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRA 1176

Query: 1219 APLKTHFRTPRP 1230
            APLK   R   P
Sbjct: 1177 APLKAALRPSGP 1188


>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
           [Homo sapiens]
          Length = 1207

 Score =  708 bits (1827), Expect = 0.0
 Identities = 354/897 (39%), Positives = 530/897 (59%), Gaps = 14/897 (1%)

Query: 25  CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81
           CD  L   L   S  +SS  S    P F+RL+   G  GW+P + +   WLQIDL ++  
Sbjct: 31  CDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90

Query: 82  IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141
           + AVATQG + S DWVT Y+L++ D   +W  + +      F GN N  +VV + L   F
Sbjct: 91  VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150

Query: 142 TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201
            AR++R +PLAWNPRG+IG+R+ +YGC YK++++YFDG  A+ Y   +   + + DV + 
Sbjct: 151 EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210

Query: 202 SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261
            FK  + +G+LLH EG  G+++TLEL    L+  ++ G++ +       T++ G +L+DQ
Sbjct: 211 KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270

Query: 262 HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321
           HWH V ++     VNFT+D +   F   GD   L+L+ E+  GG++   R     R +F 
Sbjct: 271 HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFH 330

Query: 322 GCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRG 381
           GC+EN+ +N V++ +LA +   +I   G V+F C  P   P+ F    +++ +PG     
Sbjct: 331 GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390

Query: 382 RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLND 441
           +++V+F+FRTW+  G LLF  L  G G   L L +G++ +S+ Q+G+      AG  LND
Sbjct: 391 KVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLND 450

Query: 442 GFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQT 501
           G WH V+F A+ +H  + +DD    +  V+  +LI +G +Y+FGGC   +S   C S   
Sbjct: 451 GQWHSVSFSAKWSHMNVVVDDDTAVQPLVA--VLIDSGDTYYFGGCLGNSSGSGCKSPLG 508

Query: 502 AFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDD 561
            F GC+ L+ +  + V+  LV+   LG + ++  D+CGITDRC P+ CEH G C QSWD 
Sbjct: 509 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 568

Query: 562 FICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRENR 621
           F C C  TGY GETCH+ LY++SCEA++  G  SG + ID DGSGPL PF+VYC++ ++ 
Sbjct: 569 FSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTDS- 627

Query: 622 AWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSR 681
           AWTVVRH       + G+    P       + A   ++ A  N ++ CEQ +   C  +R
Sbjct: 628 AWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGTAR 687

Query: 682 LLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRT 741
             ++  G P S+W+GR  E H  WGGS P  Q+C CGL+ +C+D   YCNCDA Q +W +
Sbjct: 688 RPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTS 747

Query: 742 DKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPP 800
           D  +L+  +HLPVTQ+V+ DT +  SEA + L PL C GD++ WN+ SF+T  + L FP 
Sbjct: 748 DTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPA 807

Query: 801 IRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDEN 860
                + DV F+F+T+  SGVF+EN+G         ++R+EL    +V F+FDVGNG   
Sbjct: 808 FHGELTADVCFFFKTTVSSGVFMENLG------ITDFIRIELRAPTEVTFSFDVGNGPCE 861

Query: 861 LTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYV 917
           +TV S    FND++WH VRAE NVK A L+VD  P  ++P P   ++ ++ +  L++
Sbjct: 862 VTVQSPT-PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI 917



 Score =  105 bits (261), Expect = 4e-22
 Identities = 55/154 (35%), Positives = 94/154 (61%), Gaps = 4/154 (2%)

Query: 1079 VTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGT--SPYVYQLTTR 1136
            +T E ++ SF T+ +P++LLYVSSF  +Y++V++ ++G+LQ+RY+L    +P  +    +
Sbjct: 956  LTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFK 1015

Query: 1137 PVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDP 1196
             + DGQ H + I R    + ++V+     +++  L   ++ ++ K+L LG+V+E    DP
Sbjct: 1016 NMADGQLHQVKINREEAVVMVEVNQS--AKKQVILSSGTEFNAVKSLILGKVLEAAGADP 1073

Query: 1197 EIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRP 1230
            + +R  T GF+GCLS VRF   APLK   R   P
Sbjct: 1074 DTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGP 1107



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 41/165 (24%), Positives = 58/165 (35%), Gaps = 27/165 (16%)

Query: 852 FDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEY 911
           F  G    N+T  +     ND +WH V          + VD    V    PL   +    
Sbjct: 433 FQAGQSPRNVTAGAG---LNDGQWHSVSFSAKWSHMNVVVDDDTAV---QPLVAVLIDSG 486

Query: 912 DQPLYVG-----SAELKRRP---FVGCLRAMRLNG-------VTLNLEGRANASEGTSPN 956
           D   + G     S    + P   F GCLR + +         V     G     +  S  
Sbjct: 487 DTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCG 546

Query: 957 CTGHCAHPRLP--CFHGGRCVERYSYYTCDCDLTAFDGPYCNHDI 999
            T  C    LP  C HGG C + +  ++CDC  T + G  C+  +
Sbjct: 547 ITDRC----LPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSL 587



 Score = 32.0 bits (71), Expect = 4.2
 Identities = 35/128 (27%), Positives = 53/128 (41%), Gaps = 8/128 (6%)

Query: 1084 VSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLR-YQLGTSPYVYQLTTRPVTDGQ 1142
            V+F F T +    LL+          VL   DG L+L  +Q G SP         + DGQ
Sbjct: 394  VTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG-LNDGQ 452

Query: 1143 PHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYN 1202
             HS++ +  + ++ + VD     +   ++L+DS         LG    +G   P      
Sbjct: 453  WHSVSFSAKWSHMNVVVDDDTAVQPLVAVLIDSGDTYYFGGCLGNSSGSGCKSP------ 506

Query: 1203 TPGFSGCL 1210
              GF GCL
Sbjct: 507  LGGFQGCL 514


>gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3
            [Homo sapiens]
          Length = 944

 Score =  344 bits (882), Expect = 4e-94
 Identities = 184/512 (35%), Positives = 286/512 (55%), Gaps = 56/512 (10%)

Query: 688  GYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRTDKGLLT 747
            G P S+W+GR  E H  WGGS P  Q+C CGL+ +C+D   YCNCDA + +W +D  +L+
Sbjct: 428  GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLS 487

Query: 748  FVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPPIRANHS 806
              +HLPVTQ+V+ D  +  SEA + L PL C GD++ WN+ SF+T  + L FP      +
Sbjct: 488  QKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELT 547

Query: 807  LDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDENLTVHSD 866
             DV F+F+T+  SGVF+EN+G         ++R+EL    +V F+FDVGNG   +TV S 
Sbjct: 548  ADVCFFFKTTVSSGVFMENLG------ITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSP 601

Query: 867  DFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSAELKRRP 926
               FND++WH VRAE NVK A L+VD  P  ++P P   ++ ++ +  L++G    ++R 
Sbjct: 602  T-PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG 660

Query: 927  FVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSYYTCDCD 986
            F+GC+R+++LNGV L+LE RA    G  P C GHC+     C +GGRC E+    TCDC 
Sbjct: 661  FLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCA 720

Query: 987  LTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYIPGYDTP 1046
             +A+DGP+C+++I  +F  G+ M Y+ Q                        Y    ++ 
Sbjct: 721  FSAYDGPFCSNEISAYFATGSSMTYHFQE----------------------HYTLSENSS 758

Query: 1047 GYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVSSFVRD 1106
              V   H             R V         +T E ++ SF T+  P++LLYVSSF  +
Sbjct: 759  SLVSSLH-------------RDV--------TLTREMITLSFRTTRTPSLLLYVSSFYEE 797

Query: 1107 YMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQVDYFPL 1164
            Y++V++ ++G+LQ+RY+L    +P  +    + + DGQ H + I R      + V+    
Sbjct: 798  YLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINR--EEAVVMVEVNQS 855

Query: 1165 TEQKFSLLVDSQLDSPKALYLGRVM-ETGVID 1195
             +++  L   ++ ++ K+L LG+V+  +G +D
Sbjct: 856  AKKQVILSSGTEFNAVKSLILGKVLGRSGPVD 887



 Score =  142 bits (359), Expect = 2e-33
 Identities = 65/136 (47%), Positives = 87/136 (63%)

Query: 487 CPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSP 546
           C   +S   C S    F GC+ L+ +  + V+  LV+   LG + ++  D+CGITDRC P
Sbjct: 187 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 246

Query: 547 NMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSG 606
           + CEH G C QSWD F C C  TGY GETCH+ LY++SCEA++  G  SG + ID DGSG
Sbjct: 247 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306

Query: 607 PLKPFVVYCDIRENRA 622
           PL PF+VYC++ +  A
Sbjct: 307 PLGPFLVYCNMTDRSA 322



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 16/135 (11%)

Query: 201 FSFKTEEKDGLLLHAEGAQGDYVTLELEG-AHLLLHMSLGSSPIQPRPGHTTVSAGGVLN 259
           F FKT    G+ +   G   D++ +EL     +     +G+ P +      TV +    N
Sbjct: 552 FFFKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCE-----VTVQSPTPFN 605

Query: 260 DQHWHYVRVDRFGRDVNFTLDGYVQRF--ILNGDFERLNLDTEMFIGGLVGAARKNLAYR 317
           D  WH+VR +R  +  +  +D   Q+          RL L++++FIGG     R      
Sbjct: 606 DNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR------ 659

Query: 318 HNFRGCIENVIFNRV 332
             F GCI ++  N V
Sbjct: 660 -GFLGCIRSLQLNGV 673



 Score = 35.4 bits (80), Expect = 0.38
 Identities = 46/222 (20%), Positives = 80/222 (36%), Gaps = 30/222 (13%)

Query: 364 NFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSI 423
           +F    +++  P F       V F F+T   +G+ +     + LG  +    E +    +
Sbjct: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFM-----ENLGITDFIRIELRAPTEV 583

Query: 424 AQS-----GRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDV--EGAEVRVSYPLLI 476
             S     G  ++   +    ND  WH V        A + +D +  +         + +
Sbjct: 584 TFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRL 643

Query: 477 RTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFD 536
           +  +  F GG           + Q  F GC+  L+++G  V L L E   +    E    
Sbjct: 644 QLNSQLFIGGTA---------TRQRGFLGCIRSLQLNG--VALDLEERATVMPGVEP--- 689

Query: 537 TCGITDRCSP--NMCEHDGRCYQSWDDFICYCELTGYKGETC 576
             G    CS   ++C + GRC +      C C  + Y G  C
Sbjct: 690 --GCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFC 729



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 11/32 (34%), Positives = 18/32 (56%)

Query: 968 CFHGGRCVERYSYYTCDCDLTAFDGPYCNHDI 999
           C HGG C + +  ++CDC  T + G  C+  +
Sbjct: 249 CEHGGECSQSWDTFSCDCLGTGYTGETCHSSL 280



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 31/138 (22%), Positives = 55/138 (39%), Gaps = 13/138 (9%)

Query: 1083 EVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGTSPY-VYQLTTRPVTDG 1141
            +V F F T+ +  V +  +  + D++ + ++    +   + +G  P  V   +  P  D 
Sbjct: 549  DVCFFFKTTVSSGVFME-NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDN 607

Query: 1142 QPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRY 1201
            Q H +   R  +   +QVD  P   Q        +L     L++G            QR 
Sbjct: 608  QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATR-------QR- 659

Query: 1202 NTPGFSGCLSGVRFNNVA 1219
               GF GC+  ++ N VA
Sbjct: 660  ---GFLGCIRSLQLNGVA 674


>gi|239743729 PREDICTED: similar to contactin associated
           protein-like 3B [Homo sapiens]
          Length = 380

 Score =  246 bits (628), Expect = 1e-64
 Identities = 121/324 (37%), Positives = 188/324 (58%), Gaps = 3/324 (0%)

Query: 25  CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81
           CD  L   L   S  +SS  S    P F+RL+   G  GW+P + +   WLQIDL ++  
Sbjct: 31  CDAPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90

Query: 82  IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141
           + AVATQG + S DWVT Y+L++ D   +W  + +      F GN N  +VV + L   F
Sbjct: 91  VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150

Query: 142 TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201
            AR++R +PLAWNPRG+IG+R+ +YGC YK++++YFDG  A+ Y   +   + + DV + 
Sbjct: 151 EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210

Query: 202 SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261
            FK  + +G+LLH EG  G+++TLEL    L+  ++ G++ +       T++ G +L+DQ
Sbjct: 211 KFKAMQSNGILLHREGQHGNHITLELIKRKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270

Query: 262 HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321
           HWH V ++     VNFT+D +   F   GD   L+L+ E+  GG+    R     R +F 
Sbjct: 271 HWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGIPTPGRSRAFTRKSFH 330

Query: 322 GCIENVIFNRVNIADLAVRRHSRI 345
           GC+EN+ +N V++ +LA +   +I
Sbjct: 331 GCLENLYYNGVDVTELAKKHKPQI 354



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 35/140 (25%), Positives = 51/140 (36%), Gaps = 11/140 (7%)

Query: 382 RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQ-------FA 434
           R  +S +F+     G+LL  R G    H+ L L + ++ V    SG  KL          
Sbjct: 205 RDVISLKFKAMQSNGILLH-REGQHGNHITLELIKRKL-VFFLNSGNAKLPSTIAPVTLT 262

Query: 435 AGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRW 494
            G  L+D  WH V           ++D              +       FGG P P    
Sbjct: 263 LGSLLDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGIPTPGR-- 320

Query: 495 DCHSNQTAFHGCMELLKVDG 514
                + +FHGC+E L  +G
Sbjct: 321 SRAFTRKSFHGCLENLYYNG 340


>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
          Length = 1477

 Score =  134 bits (336), Expect = 8e-31
 Identities = 119/451 (26%), Positives = 191/451 (42%), Gaps = 69/451 (15%)

Query: 174 ILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLL 233
           I  F G +   Y   +   +S  D    SFKT +++GL+LH  G   DYV L L+   + 
Sbjct: 283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHT-GKSADYVNLALKNGAVS 341

Query: 234 LHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGR--------------DVNFTL 279
           L ++LGS   +           G  ND  WH V+V R  R              D   T 
Sbjct: 342 LVINLGSGAFEA----LVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTT 397

Query: 280 DGYVQRFILNGDFERLNLDTEMFIGGLVGAAR-KNLAYRHNFRGCIENVIFN----RVNI 334
            GY Q      D+  L  D   ++GG    A        +NF GC++ V++     R+ +
Sbjct: 398 TGYTQE-----DYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLEL 452

Query: 335 ADLAVRRHSRITFEGKVAFRCLDPVP-HPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWD 393
           + LA +   ++   G VAF+C +     PI F  P +F+ +P +  +   ++SF FRT +
Sbjct: 453 SRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTE 512

Query: 394 LTGLLLFS----RLGDGLGHVE--------LTLSEGQVNVSIAQ-SGRKKLQFAAGYRLN 440
             GL+LFS    R      H +        + + +G + + +   SG  K++ A   ++N
Sbjct: 513 PNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIK-ALLKKVN 571

Query: 441 DGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPK-------PASR 493
           DG W+ V+F        IS++ +           ++      + GG P+       P   
Sbjct: 572 DGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEV 631

Query: 494 WDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCS-------- 545
           W    N   + GC+  L +DGQ  ++  +        AEV   T G+   CS        
Sbjct: 632 WTALLNY-GYVGCIRDLFIDGQSKDIRQM--------AEVQ-STAGVKPSCSKETAKPCL 681

Query: 546 PNMCEHDGRCYQSWDDFICYCELTGYKGETC 576
            N C+++G C   W+ ++C C  TGY G +C
Sbjct: 682 SNPCKNNGMCRDGWNRYVCDCSGTGYLGRSC 712



 Score =  107 bits (267), Expect = 8e-23
 Identities = 106/425 (24%), Positives = 184/425 (43%), Gaps = 27/425 (6%)

Query: 168  CPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG-DYVTLE 226
            C  +A +L +DG   +  + P  +     DV +  F+++   G+L+        D + LE
Sbjct: 712  CEREATVLSYDGSMFMKIQLPVVMHTEAEDV-SLRFRSQRAYGILMATTSRDSADTLRLE 770

Query: 227  LEGAHLLLHMSLGSSPIQ--PRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGY-V 283
            L+   + L ++L    I      G  T+ AG  LND  WH VRV R G+ +  T+D    
Sbjct: 771  LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 830

Query: 284  QRFILNGDFERL---NLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVR 340
                + GD  RL   N++T     G++   R   +   NF G ++++ FN +   DL   
Sbjct: 831  MTGQMAGDHTRLEFHNIET-----GIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLC-- 883

Query: 341  RHSRITF-EGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLL 399
            ++  I + E    F   + +  P+ F    ++V +        + + F+F+T  L GL+L
Sbjct: 884  KNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLIL 943

Query: 400  FSRLGDGLGHVELTLSEGQVN-VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQ-ENHAV 457
            ++  GDG   + + L +G ++ V    +G   ++ ++   LND  WH V       N   
Sbjct: 944  YNS-GDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT 1002

Query: 458  ISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWD---CHSNQTAFHGCMELLKVDG 514
            + ID     ++      L      Y  GG  K   +      H+ +  F GC+  + ++G
Sbjct: 1003 VKIDTKITTQITAGARNLDLKSDLYI-GGVAKETYKSLPKLVHAKE-GFQGCLASVDLNG 1060

Query: 515  QLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGE 574
            +L +L       L    ++     G +  C  + C + G C Q WD F C C +T + G 
Sbjct: 1061 RLPDLI---SDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGP 1117

Query: 575  TCHTP 579
             C+ P
Sbjct: 1118 LCNDP 1122



 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 119/527 (22%), Positives = 204/527 (38%), Gaps = 130/527 (24%)

Query: 760  GDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPS 819
            GD +     A+F  R +    D  ++ T S +   A     ++A  S+ + F F+T++  
Sbjct: 886  GDIDYCELNARFGFRNI--IADPVTFKTKSSYVALAT----LQAYTSMHLFFQFKTTSLD 939

Query: 820  GVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVR 879
            G+ L N G         ++ VEL     + + FD+GNG  NL   S +   ND++WH V 
Sbjct: 940  GLILYNSGDG-----NDFIVVEL-VKGYLHYVFDLGNG-ANLIKGSSNKPLNDNQWHNVM 992

Query: 880  AEINVKQAR-LRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSAELK-----------RRPF 927
               +      +++D +         +    ++    LY+G    +           +  F
Sbjct: 993  ISRDTSNLHTVKIDTKITTQITAGARN---LDLKSDLYIGGVAKETYKSLPKLVHAKEGF 1049

Query: 928  VGCLRAMRLNGVTLNLEGRA--------NASEGTSPNCTGHCAHPRLPCFHGGRCVERYS 979
             GCL ++ LNG   +L   A           EG S  C          C + G C++++ 
Sbjct: 1050 QGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDS------CSNQGVCLQQWD 1103

Query: 980  YYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGY 1039
             ++CDC +T+F GP CN       +PGT                 +++ S+         
Sbjct: 1104 GFSCDCSMTSFSGPLCN-------DPGT-----------------TYIFSK--------- 1130

Query: 1040 IPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLY 1099
                          G G     +P   RP         +   + ++  FST    AVL+ 
Sbjct: 1131 --------------GGGQITYKWPPNDRP---------STRADRLAIGFSTVQKEAVLVR 1167

Query: 1100 V--SSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSINITRVYRNLFI 1157
            V  SS + DY+ + I   G + +++ +GT     + +   + DG+ H +  TR   N  +
Sbjct: 1168 VDSSSGLGDYLELHI-HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATL 1226

Query: 1158 QVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNN 1217
            QVD +P+ E         +  + + L +     T +I  + Q      F G LSG+ +N 
Sbjct: 1227 QVDSWPVIE---------RYPAGRQLTIFNSQATIIIGGKEQ---GQPFQGQLSGLYYNG 1274

Query: 1218 VAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEVPPEL 1264
            +  L         M AE    + + G +         RLV EVP  +
Sbjct: 1275 LKVLN--------MAAENDANIAIVGNV---------RLVGEVPSSM 1304



 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 61/268 (22%), Positives = 118/268 (44%), Gaps = 36/268 (13%)

Query: 788  ISFHTGAA-LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPY---VRVELN 843
            I+F T  + +  P   A  +  +SF FRT+ P+G+ L + G P  Q    +   ++V+  
Sbjct: 482  ITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFF 541

Query: 844  TSR----DVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVD--HRPWV 897
                    +    D+G+G   + + +   + ND EW+ V  + + +   + V+    P+ 
Sbjct: 542  AIEMLDGHLYLLLDMGSG--TIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYT 599

Query: 898  LRPMPLQTYIWMEYDQPLYVGS---------------AELKRRPFVGCLRAMRLNGVTLN 942
                P ++ I ++ D  LY+G                  L    +VGC+R + ++G + +
Sbjct: 600  A---PGESEI-LDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKD 655

Query: 943  LEGRAN--ASEGTSPNCTGHCAHPRL--PCFHGGRCVERYSYYTCDCDLTAFDGPYCNHD 998
            +   A   ++ G  P+C+   A P L  PC + G C + ++ Y CDC  T + G  C  +
Sbjct: 656  IRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCERE 715

Query: 999  IGGF-FEPGTWMRYNLQSALRSAAREFS 1025
                 ++   +M+  L   + + A + S
Sbjct: 716  ATVLSYDGSMFMKIQLPVVMHTEAEDVS 743



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 41/193 (21%), Positives = 82/193 (42%), Gaps = 25/193 (12%)

Query: 175  LYFDGDDAISYRFP---RGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG--DYVTLELEG 229
            ++  G   I+Y++P   R  +R+  D  A  F T +K+ +L+  + + G  DY+ L +  
Sbjct: 1127 IFSKGGGQITYKWPPNDRPSTRA--DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQ 1184

Query: 230  AHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGY--VQRFI 287
              + +  ++G+  I          +  ++ND  +H VR  R G +    +D +  ++R+ 
Sbjct: 1185 GKIGVKFNVGTDDI------AIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYP 1238

Query: 288  LNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITF 347
                    N    + IGG              F+G +  + +N + + ++A    + I  
Sbjct: 1239 AGRQLTIFNSQATIIIGG--------KEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAI 1290

Query: 348  EGKVAFRCLDPVP 360
             G V  R +  VP
Sbjct: 1291 VGNV--RLVGEVP 1301



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 101/477 (21%), Positives = 170/477 (35%), Gaps = 87/477 (18%)

Query: 776  LRCYGDRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRR 835
            L C+ +  S        G   RFP   A    ++SF  +T +  G+ L      +C    
Sbjct: 21   LGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCD--- 77

Query: 836  PYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDH-- 893
             ++ + L     +  +F +   +    +   D   ND  WH VR     +   L +D   
Sbjct: 78   -FLELILTRGGRLQLSFSIFCAEPATLLA--DTPVNDGAWHSVRIRRQFRNTTLFIDQVE 134

Query: 894  RPWV-----LRPMPLQTYIWMEYDQPLYVGSAELK--------RRPFVGCLRAMRLNGVT 940
              WV      R M + + +++    P  + +A LK        R PF G +R +R+N   
Sbjct: 135  AKWVEVKSKRRDMTVFSGLFVG-GLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQ 193

Query: 941  L--------NLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDG 992
            +         L+     S G SP   G      + C +GG C        CDC  T F G
Sbjct: 194  VLPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGV-CLNGGVCSVVDDQAVCDCSRTGFRG 252

Query: 993  PYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYIPGYDTPGYVPGY 1052
              C+ +                    +     +H++       + G   G +   Y+  +
Sbjct: 253  KDCSQE-------------------DNNVEGLAHLMMG-----DQGKSKGKEE--YIATF 286

Query: 1053 HGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLI 1112
             G  Y   D           + P+ + + +E++ SF T     ++L+      DY+ + +
Sbjct: 287  KGSEYFCYDLS---------QNPIQS-SSDEITLSFKTLQRNGLMLHTGKSA-DYVNLAL 335

Query: 1113 KDDGTLQLRYQLGTSPYVYQLTTRPV----TDGQPHSINITRVYRN--------LFIQVD 1160
            K +G + L   LG+    ++    PV     D   H + +TR  R         + I VD
Sbjct: 336  K-NGAVSLVINLGSG--AFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVD 392

Query: 1161 YFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNN 1217
               LT   ++    + L S    Y+G    T  +       N   F GCL  V + N
Sbjct: 393  GI-LTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNN---FMGCLKEVVYKN 445



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 52/214 (24%), Positives = 78/214 (36%), Gaps = 34/214 (15%)

Query: 385 VSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEG-QVNVSIAQSGRKKLQFAAGYRLNDGF 443
           +SF+ +T    GL+L+         +EL L+ G ++ +S +    +     A   +NDG 
Sbjct: 54  MSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGA 113

Query: 444 WHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTS-YFFGGCP-------------- 488
           WH V    Q  +  + ID VE   V V       T  S  F GG P              
Sbjct: 114 WHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLAS 173

Query: 489 ----KPASRW--DCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITD 542
               +P   W  D   N +      ++L VD   V L        G         C   +
Sbjct: 174 VREREPFKGWIRDVRVNSS------QVLPVDSGEVKLDDEPPNSGG------GSPCEAGE 221

Query: 543 RCSPNMCEHDGRCYQSWDDFICYCELTGYKGETC 576
                +C + G C    D  +C C  TG++G+ C
Sbjct: 222 EGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDC 255



 Score = 34.7 bits (78), Expect = 0.65
 Identities = 45/168 (26%), Positives = 73/168 (43%), Gaps = 20/168 (11%)

Query: 175 LYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLEL---EGAH 231
           L F G +    RFP+  +       +F  KT    GL+L+ +  +G    LEL    G  
Sbjct: 31  LEFPGAEGQWTRFPKW-NACCESEMSFQLKTRSARGLVLYFDD-EGFCDFLELILTRGGR 88

Query: 232 LLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFI-LNG 290
           L L  S+  +  +P     T+ A   +ND  WH VR+ R  R+    +D    +++ +  
Sbjct: 89  LQLSFSIFCA--EP----ATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKS 142

Query: 291 DFERLNLDTEMFIGGL-----VGAARKNLA---YRHNFRGCIENVIFN 330
               + + + +F+GGL       A +  LA    R  F+G I +V  N
Sbjct: 143 KRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVN 190



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 7/101 (6%)

Query: 796 LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYV---RVELNTSRDVV-FA 851
           ++ P +    + DVS  FR+    G+ +           R  +   RV+L  + D +   
Sbjct: 729 IQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRIN 788

Query: 852 FDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVD 892
            +   G E L      +  ND+EWH VR     K  +L VD
Sbjct: 789 CNSSKGPETLFA---GYNLNDNEWHTVRVVRRGKSLKLTVD 826



 Score = 31.2 bits (69), Expect = 7.2
 Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 25/169 (14%)

Query: 800 PIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDE 859
           PI+++ S +++  F+T   +G+ L             YV + L     V    ++G+G  
Sbjct: 300 PIQSS-SDEITLSFKTLQRNGLMLHTGKSA------DYVNLALKNGA-VSLVINLGSGAF 351

Query: 860 NLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQT--------YIWMEY 911
              V   + +FND+ WH V+   N++Q    + H    +    + T        Y  +  
Sbjct: 352 EALVEPVNGKFNDNAWHDVKVTRNLRQ-HSGIGHAMVTISVDGILTTTGYTQEDYTMLGS 410

Query: 912 DQPLYVG----SAELKRRP----FVGCLRAMRLNGVTLNLEGRANASEG 952
           D   YVG    +A+L   P    F+GCL+ +      + LE    A +G
Sbjct: 411 DDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQG 459


>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
          Length = 1642

 Score =  133 bits (335), Expect = 1e-30
 Identities = 118/442 (26%), Positives = 190/442 (42%), Gaps = 56/442 (12%)

Query: 177 FDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHM 236
           F G++   Y       +S  D    +F+T +++GL+LH  G   DYV L L+   + L +
Sbjct: 268 FKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHT-GKSADYVNLSLKSGAVWLVI 326

Query: 237 SLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGR--------------DVNFTLDGY 282
           +LGS   +           G  ND  WH VRV R  R              D   T  GY
Sbjct: 327 NLGSGAFEA----LVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTTTGY 382

Query: 283 VQRFILNGDFERLNLDTEMFIGGLVGAAR-KNLAYRHNFRGCIENVIFN----RVNIADL 337
            Q      D+  L  D   +IGG    A        +NF GC+++V++     ++ ++ L
Sbjct: 383 TQE-----DYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRL 437

Query: 338 AVRRHSRITFEGKVAFRCLDPVP-HPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTG 396
           A     ++  +G ++FRC D     P+ F  P  FV +P +  +   ++S  FRT +  G
Sbjct: 438 AKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNG 497

Query: 397 LLLFS---RLGDGLG---------HVELTLSEGQVNVSIAQ-SGRKKLQFAAGYRLNDGF 443
           LLLFS   R G G G         +  + L +G + + +   SG  KL+ A+  ++NDG 
Sbjct: 498 LLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLR-ASSRKVNDGE 556

Query: 444 WHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPK--------PASRWD 495
           W  V+F        IS++      +      ++   +  + GG P+        P   W 
Sbjct: 557 WCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWT 616

Query: 496 CHSNQTAFHGCMELLKVDGQLVNLT-LVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGR 554
             + +  + GC+  L +DG+  +L  L E +  G      F +     +C+   C + G 
Sbjct: 617 A-ALRAGYVGCVRDLFIDGRSRDLRGLAEAQ--GAVGVAPFCSRETLKQCASAPCRNGGV 673

Query: 555 CYQSWDDFICYCELTGYKGETC 576
           C + W+ FIC C  TG+ G  C
Sbjct: 674 CREGWNRFICDCIGTGFLGRVC 695



 Score =  112 bits (279), Expect = 3e-24
 Identities = 110/427 (25%), Positives = 183/427 (42%), Gaps = 41/427 (9%)

Query: 168  CPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG-DYVTLE 226
            C  +A +L +DG   +    P  +     DV +  F ++   GL++     +  D + LE
Sbjct: 695  CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 753

Query: 227  LEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRF 286
            L+G  + L ++LG  P        T+ AG  LND  WH VRV R G+ +  ++D      
Sbjct: 754  LDGGQMKLTVNLGKGP-------ETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEG 806

Query: 287  ILNGDFERL---NLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHS 343
             + G   RL   N++T     G++   R       NF G +  ++FN     D    +  
Sbjct: 807  QMAGAHMRLEFHNIET-----GIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQC--KDG 859

Query: 344  RITF-EGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSR 402
             IT+ E    F     V  P+ F    +++ +        + + F+F+T    GLLLF+ 
Sbjct: 860  DITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNS 919

Query: 403  LGDGLGHVELTLSEGQVN-VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQE--NHAVIS 459
             G+G   + + L +G ++ V    +G   ++  +   +ND  WH V  V+++  N   + 
Sbjct: 920  -GNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNV-VVSRDPGNVHTLK 977

Query: 460  IDD------VEGAE-VRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKV 512
            ID         GA  + +   L I   +   F   PK  +  D       F GC+  + +
Sbjct: 978  IDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRD------GFQGCLASVDL 1031

Query: 513  DGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYK 572
            +G+L +L      R+G   +V     G +  C+   C + G C Q WD F C C +T Y 
Sbjct: 1032 NGRLPDLIADALHRIG---QVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYG 1088

Query: 573  GETCHTP 579
            G  C+ P
Sbjct: 1089 GPVCNDP 1095



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 116/491 (23%), Positives = 188/491 (38%), Gaps = 124/491 (25%)

Query: 796  LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVG 855
            L    ++A  S+ + F F+T+AP G+ L N G         ++ +EL     + + FD+G
Sbjct: 889  LALATLQAYASMHLFFQFKTTAPDGLLLFNSGNG-----NDFIVIEL-VKGYIHYVFDLG 942

Query: 856  NGDENLTVHSDDFEFNDDEWHLVRAEINVKQAR-LRVDHRPWVLRPMPLQTYIWMEYDQP 914
            NG   +  +SD    ND++WH V    +      L++D R         +    ++    
Sbjct: 943  NGPSLMKGNSDK-PVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARN---LDLKGE 998

Query: 915  LYVGSAE-----------LKRRPFVGCLRAMRLNGVTLNLEGRA--------NASEGTSP 955
            LY+G                R  F GCL ++ LNG   +L   A           +G S 
Sbjct: 999  LYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPST 1058

Query: 956  NCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQS 1015
             CT         C + G C++++  +TCDC +T++ GP CN       +PGT   +    
Sbjct: 1059 TCTEES------CANQGVCLQQWDGFTCDCTMTSYGGPVCN-------DPGTTYIFGKGG 1105

Query: 1016 ALRSAAREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGP 1075
            AL +                                     Y  P   RP   +      
Sbjct: 1106 ALIT-------------------------------------YTWPPNDRPSTRM------ 1122

Query: 1076 VYNVTGEEVSFSFSTSSAPAVLLYV--SSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQL 1133
                  + ++  FST    AVL+ V  +S + DY+ + I D GT+ + + +GT       
Sbjct: 1123 ------DRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-DQGTVGVIFNVGTDDITIDE 1175

Query: 1134 TTRPVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGV 1193
                V+DG+ H +  TR   N  +QVD +P+ E+  +    +  +S  A+ +G       
Sbjct: 1176 PNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGRQLTIFNSQAAIKIG------- 1228

Query: 1194 IDPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAM 1253
                  R     F G +SG+ +N +  L         + AE    +R +G L        
Sbjct: 1229 -----GRDQGRPFQGQVSGLYYNGLKVL--------ALAAESDPNVRTEGHL-------- 1267

Query: 1254 PRLVSEVPPEL 1264
             RLV E P  L
Sbjct: 1268 -RLVGEGPSVL 1277



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 160/712 (22%), Positives = 271/712 (38%), Gaps = 109/712 (15%)

Query: 385  VSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLNDGFW 444
            +SF  RT     LLL+   G     +EL L +G++ +    S  +         + D  W
Sbjct: 53   LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRW 112

Query: 445  HEVNFVAQENHAVISID-DVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTA- 502
            H V          +++D +   AEVR S    ++  +  F GG P P  R    +  T  
Sbjct: 113  HMVLLTRDARRTALAVDGEARAAEVR-SKRREMQVASDLFVGGIP-PDVRLSALTLSTVK 170

Query: 503  ----FHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSP--NMCEHDGRC- 555
                F G +  LK+  +   L   +G R G  A+ L         C+P  N C + G C 
Sbjct: 171  YEPPFRGLLANLKLGERPPALLGSQGLR-GATADPL---------CAPARNPCANGGLCT 220

Query: 556  YQSWDDFICYCELTGYKGETC-----------HTPLYKESCEAYRLSGKTSGNFTID--- 601
              +  +  C C  TG+ G+ C           H  L  E  E +  + K +  F  D   
Sbjct: 221  VLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVATFKGNEFFCYDLSH 280

Query: 602  -PDGSGPLKPFVVYCDIRENRAWT-----------VVRHDRLWTTRVTGSSMERPFLGAI 649
             P  S   +  + +  ++ N                ++   +W     GS      +  +
Sbjct: 281  NPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEALVEPV 340

Query: 650  --QYWNASWEEVSALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGG 707
              ++ + +W +V    N  QH          +   + T  GY    +     +  FY GG
Sbjct: 341  NGKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYIGG 400

Query: 708  SQPGIQRCACGLDRS---CVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNR 764
            S          +  +   C+   +Y N D      R  K                GD   
Sbjct: 401  SPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKE---------------GDPKM 445

Query: 765  STSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPPIRANHSLDVSFYFRTSAPSGVFL 823
                   F    RC  D  + + ++F +  A +  P   A  +  +S  FRT+ P+G+ L
Sbjct: 446  KLQGDLSF----RCE-DVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLL 500

Query: 824  ENMG-------GPYCQWRRP-YVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEW 875
             + G       G +   +R  Y  +EL     +    D+G+G   L   S   + ND EW
Sbjct: 501  FSQGRRAGGGAGSHSSAQRADYFAMELLDGH-LYLLLDMGSGGIKLRASSR--KVNDGEW 557

Query: 876  HLVRAEINVKQARLRVDHR--PWVLRP----MPLQTYIWM-------EYDQPL--YVGSA 920
              V  + + ++  + V+ R  P++       + L++ +++         D PL   V +A
Sbjct: 558  CHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTA 617

Query: 921  ELKRRPFVGCLRAMRLNGVTLNLEGRANA--SEGTSPNCTGH----CAHPRLPCFHGGRC 974
             L R  +VGC+R + ++G + +L G A A  + G +P C+      CA    PC +GG C
Sbjct: 618  AL-RAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASA--PCRNGGVC 674

Query: 975  VERYSYYTCDCDLTAFDGPYCNHDIGGF-FEPGTWMRYNLQSALRSAAREFS 1025
             E ++ + CDC  T F G  C  +     ++   +M+  L +A+ + A + S
Sbjct: 675  REGWNRFICDCIGTGFLGRVCEREATVLSYDGSMYMKIMLPNAMHTEAEDVS 726



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 89/410 (21%), Positives = 142/410 (34%), Gaps = 82/410 (20%)

Query: 153 WNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLL 212
           W P     L L L     +AD L F G      R+ R    +     +FS +T     LL
Sbjct: 7   WRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTNATRALL 66

Query: 213 LHAE-GAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRF 271
           L+ + G   D++ L L    L L  +L  +  +P     T+     + D  WH V + R 
Sbjct: 67  LYLDDGGDCDFLELLLVDGRLRLRFTLSCA--EP----ATLQLDTPVADDRWHMVLLTRD 120

Query: 272 GRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAAR------KNLAYRHNFRGCIE 325
            R     +DG  +   +      + + +++F+GG+    R        + Y   FRG + 
Sbjct: 121 ARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLA 180

Query: 326 NVIFN------------RVNIAD--LAVRRH--------------------SRITFEGKV 351
           N+               R   AD   A  R+                    S   F GK 
Sbjct: 181 NLKLGERPPALLGSQGLRGATADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKF 240

Query: 352 AFRCLDPVPHP----INFGGPHNFVQV--------------PGFPRRGRLAVSFRFRTWD 393
                 P+  P    +N  G   FV                P       + ++FR  T  
Sbjct: 241 CSEEEHPMEGPAHLTLNSEGKEEFVATFKGNEFFCYDLSHNPIQSSTDEITLAFR--TLQ 298

Query: 394 LTGLLLFSRLGDGLGHVELTLSEGQV--NVSIAQSGRKKLQFAAGYRLNDGFWHEVNFV- 450
             GL+L +  G    +V L+L  G V   +++     + L      + ND  WH+V    
Sbjct: 299 RNGLMLHT--GKSADYVNLSLKSGAVWLVINLGSGAFEALVEPVNGKFNDNAWHDVRVTR 356

Query: 451 -----AQENHAVISIDDVEGAEVRVSYP----LLIRTGTSYFFGGCPKPA 491
                A   HA+++I  V+G      Y      ++ +   ++ GG P  A
Sbjct: 357 NLRQHAGIGHAMVTI-SVDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTA 405



 Score = 40.4 bits (93), Expect = 0.012
 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 1083 EVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLG-TSPYVYQLTTRPVTDG 1141
            E+SFS  T++  A+LLY+          L+  DG L+LR+ L    P   QL T PV D 
Sbjct: 52   ELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDT-PVADD 110

Query: 1142 QPHSINITRVYRNLFIQVD 1160
            + H + +TR  R   + VD
Sbjct: 111  RWHMVLLTRDARRTALAVD 129


>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
          Length = 1547

 Score =  131 bits (329), Expect = 5e-30
 Identities = 119/458 (25%), Positives = 191/458 (41%), Gaps = 76/458 (16%)

Query: 174 ILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLL 233
           I  F G +   Y   +   +S  D    SFKT +++GL+LH  G   DYV L L+   + 
Sbjct: 316 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHT-GKSADYVNLALKNGAVS 374

Query: 234 LHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGR-------------------- 273
           L ++LGS   +           G  ND  WH V+V R  R                    
Sbjct: 375 LVINLGSGAFEA----LVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTIS 430

Query: 274 -DVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAAR-KNLAYRHNFRGCIENVIFN- 330
            D   T  GY Q      D+  L  D   ++GG    A        +NF GC++ V++  
Sbjct: 431 VDGILTTTGYTQE-----DYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKN 485

Query: 331 ---RVNIADLAVRRHSRITFEGKVAFRCLDPVP-HPINFGGPHNFVQVPGFPRRGRLAVS 386
              R+ ++ LA +   ++   G VAF+C +     PI F  P +F+ +P +  +   ++S
Sbjct: 486 NDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSIS 545

Query: 387 FRFRTWDLTGLLLFS----RLGDGLGHVE--------LTLSEGQVNVSIAQ-SGRKKLQF 433
           F FRT +  GL+LFS    R      H +        + + +G + + +   SG  K++ 
Sbjct: 546 FDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIK- 604

Query: 434 AAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPK---- 489
           A   ++NDG W+ V+F        IS++ +           ++      + GG P+    
Sbjct: 605 ALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAG 664

Query: 490 ---PASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCS- 545
              P   W    N   + GC+  L +DGQ  ++  +        AEV   T G+   CS 
Sbjct: 665 LVFPTEVWTALLNY-GYVGCIRDLFIDGQSKDIRQM--------AEVQ-STAGVKPSCSK 714

Query: 546 -------PNMCEHDGRCYQSWDDFICYCELTGYKGETC 576
                   N C+++G C   W+ ++C C  TGY G +C
Sbjct: 715 ETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSC 752



 Score =  107 bits (267), Expect = 8e-23
 Identities = 106/425 (24%), Positives = 184/425 (43%), Gaps = 27/425 (6%)

Query: 168  CPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG-DYVTLE 226
            C  +A +L +DG   +  + P  +     DV +  F+++   G+L+        D + LE
Sbjct: 752  CEREATVLSYDGSMFMKIQLPVVMHTEAEDV-SLRFRSQRAYGILMATTSRDSADTLRLE 810

Query: 227  LEGAHLLLHMSLGSSPIQ--PRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGY-V 283
            L+   + L ++L    I      G  T+ AG  LND  WH VRV R G+ +  T+D    
Sbjct: 811  LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 870

Query: 284  QRFILNGDFERL---NLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVR 340
                + GD  RL   N++T     G++   R   +   NF G ++++ FN +   DL   
Sbjct: 871  MTGQMAGDHTRLEFHNIET-----GIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLC-- 923

Query: 341  RHSRITF-EGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLL 399
            ++  I + E    F   + +  P+ F    ++V +        + + F+F+T  L GL+L
Sbjct: 924  KNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLIL 983

Query: 400  FSRLGDGLGHVELTLSEGQVN-VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQ-ENHAV 457
            ++  GDG   + + L +G ++ V    +G   ++ ++   LND  WH V       N   
Sbjct: 984  YNS-GDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT 1042

Query: 458  ISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWD---CHSNQTAFHGCMELLKVDG 514
            + ID     ++      L      Y  GG  K   +      H+ +  F GC+  + ++G
Sbjct: 1043 VKIDTKITTQITAGARNLDLKSDLYI-GGVAKETYKSLPKLVHAKE-GFQGCLASVDLNG 1100

Query: 515  QLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGE 574
            +L +L       L    ++     G +  C  + C + G C Q WD F C C +T + G 
Sbjct: 1101 RLPDLI---SDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGP 1157

Query: 575  TCHTP 579
             C+ P
Sbjct: 1158 LCNDP 1162



 Score = 84.3 bits (207), Expect = 7e-16
 Identities = 123/545 (22%), Positives = 216/545 (39%), Gaps = 136/545 (24%)

Query: 760  GDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPS 819
            GD +     A+F  R +    D  ++ T S +   A     ++A  S+ + F F+T++  
Sbjct: 926  GDIDYCELNARFGFRNI--IADPVTFKTKSSYVALAT----LQAYTSMHLFFQFKTTSLD 979

Query: 820  GVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVR 879
            G+ L N G         ++ VEL     + + FD+GNG  NL   S +   ND++WH V 
Sbjct: 980  GLILYNSGDG-----NDFIVVEL-VKGYLHYVFDLGNG-ANLIKGSSNKPLNDNQWHNVM 1032

Query: 880  AEINVKQAR-LRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSAELK-----------RRPF 927
               +      +++D +         +    ++    LY+G    +           +  F
Sbjct: 1033 ISRDTSNLHTVKIDTKITTQITAGARN---LDLKSDLYIGGVAKETYKSLPKLVHAKEGF 1089

Query: 928  VGCLRAMRLNGVTLNLEGRA--------NASEGTSPNCTGHCAHPRLPCFHGGRCVERYS 979
             GCL ++ LNG   +L   A           EG S  C          C + G C++++ 
Sbjct: 1090 QGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDS------CSNQGVCLQQWD 1143

Query: 980  YYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGY 1039
             ++CDC +T+F GP CN       +PGT                 +++ S+         
Sbjct: 1144 GFSCDCSMTSFSGPLCN-------DPGT-----------------TYIFSK--------- 1170

Query: 1040 IPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLY 1099
                          G G     +P   RP         +   + ++  FST    AVL+ 
Sbjct: 1171 --------------GGGQITYKWPPNDRP---------STRADRLAIGFSTVQKEAVLVR 1207

Query: 1100 V--SSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSINITRVYRNLFI 1157
            V  SS + DY+ + I   G + +++ +GT     + +   + DG+ H +  TR   N  +
Sbjct: 1208 VDSSSGLGDYLELHI-HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATL 1266

Query: 1158 QVDYFPLTEQKFSLLVDSQ---LDSPKALY-LGRVMETGVIDP--EIQRYNTPG------ 1205
            QVD +P+ E+  +   D++   +   +  Y LGRV++  ++D   ++  +N+        
Sbjct: 1267 QVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGG 1326

Query: 1206 ------FSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSE 1259
                  F G LSG+ +N +  L         M AE    + + G +         RLV E
Sbjct: 1327 KEQGQPFQGQLSGLYYNGLKVLN--------MAAENDANIAIVGNV---------RLVGE 1369

Query: 1260 VPPEL 1264
            VP  +
Sbjct: 1370 VPSSM 1374



 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 61/268 (22%), Positives = 118/268 (44%), Gaps = 36/268 (13%)

Query: 788  ISFHTGAA-LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPY---VRVELN 843
            I+F T  + +  P   A  +  +SF FRT+ P+G+ L + G P  Q    +   ++V+  
Sbjct: 522  ITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFF 581

Query: 844  TSR----DVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVD--HRPWV 897
                    +    D+G+G   + + +   + ND EW+ V  + + +   + V+    P+ 
Sbjct: 582  AIEMLDGHLYLLLDMGSG--TIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYT 639

Query: 898  LRPMPLQTYIWMEYDQPLYVGS---------------AELKRRPFVGCLRAMRLNGVTLN 942
                P ++ I ++ D  LY+G                  L    +VGC+R + ++G + +
Sbjct: 640  A---PGESEI-LDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKD 695

Query: 943  LEGRAN--ASEGTSPNCTGHCAHPRL--PCFHGGRCVERYSYYTCDCDLTAFDGPYCNHD 998
            +   A   ++ G  P+C+   A P L  PC + G C + ++ Y CDC  T + G  C  +
Sbjct: 696  IRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCERE 755

Query: 999  IGGF-FEPGTWMRYNLQSALRSAAREFS 1025
                 ++   +M+  L   + + A + S
Sbjct: 756  ATVLSYDGSMFMKIQLPVVMHTEAEDVS 783



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 2/98 (2%)

Query: 1065 PGRPVPGYRGPVYNVTGE-EVSFSFSTSSAPAVLLYVSSF-VRDYMAVLIKDDGTLQLRY 1122
            PG      R P +N   E E+SF   T SA  ++LY       D++ +++   G LQL +
Sbjct: 34   PGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSF 93

Query: 1123 QLGTSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQVD 1160
             +  +     L   PV DG  HS+ I R +RN  + +D
Sbjct: 94   SIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLFID 131



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 58/247 (23%), Positives = 92/247 (37%), Gaps = 31/247 (12%)

Query: 776 LRCYGDRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRR 835
           L C+ +  S        G   RFP   A    ++SF  +T +  G+ L      +C    
Sbjct: 21  LGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCD--- 77

Query: 836 PYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDH-- 893
            ++ + L     +  +F +   +    +   D   ND  WH VR     +   L +D   
Sbjct: 78  -FLELILTRGGRLQLSFSIFCAEPATLLA--DTPVNDGAWHSVRIRRQFRNTTLFIDQVE 134

Query: 894 RPWV-----LRPMPLQTYIWMEYDQPLYVGSAELK--------RRPFVGCLRAMRLNGVT 940
             WV      R M + + +++    P  + +A LK        R PF G +R +R+N   
Sbjct: 135 AKWVEVKSKRRDMTVFSGLFVG-GLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQ 193

Query: 941 L--------NLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDG 992
           +         L+     S G SP   G      + C +GG C        CDC  T F G
Sbjct: 194 VLPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGV-CLNGGVCSVVDDQAVCDCSRTGFRG 252

Query: 993 PYCNHDI 999
             C+ +I
Sbjct: 253 KDCSQEI 259



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 52/214 (24%), Positives = 78/214 (36%), Gaps = 34/214 (15%)

Query: 385 VSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEG-QVNVSIAQSGRKKLQFAAGYRLNDGF 443
           +SF+ +T    GL+L+         +EL L+ G ++ +S +    +     A   +NDG 
Sbjct: 54  MSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGA 113

Query: 444 WHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTS-YFFGGCP-------------- 488
           WH V    Q  +  + ID VE   V V       T  S  F GG P              
Sbjct: 114 WHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLAS 173

Query: 489 ----KPASRW--DCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITD 542
               +P   W  D   N +      ++L VD   V L        G         C   +
Sbjct: 174 VREREPFKGWIRDVRVNSS------QVLPVDSGEVKLDDEPPNSGG------GSPCEAGE 221

Query: 543 RCSPNMCEHDGRCYQSWDDFICYCELTGYKGETC 576
                +C + G C    D  +C C  TG++G+ C
Sbjct: 222 EGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDC 255



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 32/129 (24%), Positives = 62/129 (48%), Gaps = 16/129 (12%)

Query: 175  LYFDGDDAISYRFP---RGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG--DYVTLELEG 229
            ++  G   I+Y++P   R  +R+  D  A  F T +K+ +L+  + + G  DY+ L +  
Sbjct: 1167 IFSKGGGQITYKWPPNDRPSTRA--DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQ 1224

Query: 230  AHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGY--VQRFI 287
              + +  ++G+  I          +  ++ND  +H VR  R G +    +D +  ++R+ 
Sbjct: 1225 GKIGVKFNVGTDDI------AIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYP 1278

Query: 288  L-NGDFERL 295
              N D ERL
Sbjct: 1279 AGNNDNERL 1287



 Score = 34.7 bits (78), Expect = 0.65
 Identities = 45/168 (26%), Positives = 73/168 (43%), Gaps = 20/168 (11%)

Query: 175 LYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLEL---EGAH 231
           L F G +    RFP+  +       +F  KT    GL+L+ +  +G    LEL    G  
Sbjct: 31  LEFPGAEGQWTRFPKW-NACCESEMSFQLKTRSARGLVLYFDD-EGFCDFLELILTRGGR 88

Query: 232 LLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFI-LNG 290
           L L  S+  +  +P     T+ A   +ND  WH VR+ R  R+    +D    +++ +  
Sbjct: 89  LQLSFSIFCA--EP----ATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKS 142

Query: 291 DFERLNLDTEMFIGGL-----VGAARKNLA---YRHNFRGCIENVIFN 330
               + + + +F+GGL       A +  LA    R  F+G I +V  N
Sbjct: 143 KRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVN 190



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 7/101 (6%)

Query: 796 LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYV---RVELNTSRDVV-FA 851
           ++ P +    + DVS  FR+    G+ +           R  +   RV+L  + D +   
Sbjct: 769 IQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRIN 828

Query: 852 FDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVD 892
            +   G E L      +  ND+EWH VR     K  +L VD
Sbjct: 829 CNSSKGPETLFA---GYNLNDNEWHTVRVVRRGKSLKLTVD 866


>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
          Length = 1712

 Score =  130 bits (328), Expect = 7e-30
 Identities = 118/449 (26%), Positives = 190/449 (42%), Gaps = 63/449 (14%)

Query: 177 FDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHM 236
           F G++   Y       +S  D    +F+T +++GL+LH  G   DYV L L+   + L +
Sbjct: 292 FKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHT-GKSADYVNLSLKSGAVWLVI 350

Query: 237 SLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGR---------------------DV 275
           +LGS   +           G  ND  WH VRV R  R                     D 
Sbjct: 351 NLGSGAFEA----LVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDG 406

Query: 276 NFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAAR-KNLAYRHNFRGCIENVIFN---- 330
             T  GY Q      D+  L  D   +IGG    A        +NF GC+++V++     
Sbjct: 407 ILTTTGYTQE-----DYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDF 461

Query: 331 RVNIADLAVRRHSRITFEGKVAFRCLDPVP-HPINFGGPHNFVQVPGFPRRGRLAVSFRF 389
           ++ ++ LA     ++  +G ++FRC D     P+ F  P  FV +P +  +   ++S  F
Sbjct: 462 KLELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDF 521

Query: 390 RTWDLTGLLLFS---RLGDGLG---------HVELTLSEGQVNVSIAQ-SGRKKLQFAAG 436
           RT +  GLLLFS   R G G G         +  + L +G + + +   SG  KL+ A+ 
Sbjct: 522 RTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLR-ASS 580

Query: 437 YRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPK------- 489
            ++NDG W  V+F        IS++      +      ++   +  + GG P+       
Sbjct: 581 RKVNDGEWCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGGLPEGGRVDLP 640

Query: 490 -PASRWDCHSNQTAFHGCMELLKVDGQLVNLT-LVEGRRLGFYAEVLFDTCGITDRCSPN 547
            P   W   + +  + GC+  L +DG+  +L  L E +  G      F +     +C+  
Sbjct: 641 LPPEVWTA-ALRAGYVGCVRDLFIDGRSRDLRGLAEAQ--GAVGVAPFCSRETLKQCASA 697

Query: 548 MCEHDGRCYQSWDDFICYCELTGYKGETC 576
            C + G C + W+ FIC C  TG+ G  C
Sbjct: 698 PCRNGGVCREGWNRFICDCIGTGFLGRVC 726



 Score =  110 bits (276), Expect = 7e-24
 Identities = 110/429 (25%), Positives = 184/429 (42%), Gaps = 36/429 (8%)

Query: 168  CPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG-DYVTLE 226
            C  +A +L +DG   +    P  +     DV +  F ++   GL++     +  D + LE
Sbjct: 726  CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 784

Query: 227  LEGAHLLLHMSLGSSPI--QPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQ 284
            L+G  + L ++L    +   P  G  T+ AG  LND  WH VRV R G+ +  ++D    
Sbjct: 785  LDGGQMKLTVNLDCLRVGCAPSKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTV 844

Query: 285  RFILNGDFERL---NLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRR 341
               + G   RL   N++T     G++   R       NF G +  ++FN     D    +
Sbjct: 845  EGQMAGAHMRLEFHNIET-----GIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQC--K 897

Query: 342  HSRITF-EGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLF 400
               IT+ E    F     V  P+ F    +++ +        + + F+F+T    GLLLF
Sbjct: 898  DGDITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLF 957

Query: 401  SRLGDGLGHVELTLSEGQVN-VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQE--NHAV 457
            +  G+G   + + L +G ++ V    +G   ++  +   +ND  WH V  V+++  N   
Sbjct: 958  NS-GNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNV-VVSRDPGNVHT 1015

Query: 458  ISIDD------VEGAE-VRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELL 510
            + ID         GA  + +   L I   +   F   PK  +  D       F GC+  +
Sbjct: 1016 LKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRD------GFQGCLASV 1069

Query: 511  KVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTG 570
             ++G+L +L      R+G   +V     G +  C+   C + G C Q WD F C C +T 
Sbjct: 1070 DLNGRLPDLIADALHRIG---QVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTS 1126

Query: 571  YKGETCHTP 579
            Y G  C+ P
Sbjct: 1127 YGGPVCNDP 1135



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 120/509 (23%), Positives = 200/509 (39%), Gaps = 130/509 (25%)

Query: 796  LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVG 855
            L    ++A  S+ + F F+T+AP G+ L N G         ++ +EL     + + FD+G
Sbjct: 929  LALATLQAYASMHLFFQFKTTAPDGLLLFNSGNG-----NDFIVIEL-VKGYIHYVFDLG 982

Query: 856  NGDENLTVHSDDFEFNDDEWHLVRAEINVKQAR-LRVDHRPWVLRPMPLQTYIWMEYDQP 914
            NG   +  +SD    ND++WH V    +      L++D R         +    ++    
Sbjct: 983  NGPSLMKGNSDK-PVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARN---LDLKGE 1038

Query: 915  LYVGSAE-----------LKRRPFVGCLRAMRLNGVTLNLEGRA--------NASEGTSP 955
            LY+G                R  F GCL ++ LNG   +L   A           +G S 
Sbjct: 1039 LYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPST 1098

Query: 956  NCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQS 1015
             CT         C + G C++++  +TCDC +T++ GP CN       +PGT   +    
Sbjct: 1099 TCTEES------CANQGVCLQQWDGFTCDCTMTSYGGPVCN-------DPGTTYIFGKGG 1145

Query: 1016 ALRSAAREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGP 1075
            AL +                                     Y  P   RP   +      
Sbjct: 1146 ALIT-------------------------------------YTWPPNDRPSTRM------ 1162

Query: 1076 VYNVTGEEVSFSFSTSSAPAVLLYV--SSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQL 1133
                  + ++  FST    AVL+ V  +S + DY+ + I D GT+ + + +GT       
Sbjct: 1163 ------DRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-DQGTVGVIFNVGTDDITIDE 1215

Query: 1134 TTRPVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQ---LDSPKALY-LGRVM 1189
                V+DG+ H +  TR   N  +QVD +P+ E+  +   D++   +   +  Y LGRV+
Sbjct: 1216 PNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVV 1275

Query: 1190 ETGVIDP--EIQRYNTPG------------FSGCLSGVRFNNVAPLKTHFRTPRPMTAEL 1235
            +  ++D   ++  +N+              F G +SG+ +N +  L         + AE 
Sbjct: 1276 DEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVL--------ALAAES 1327

Query: 1236 AEALRVQGELSESNCGAMPRLVSEVPPEL 1264
               +R +G L         RLV E P  L
Sbjct: 1328 DPNVRTEGHL---------RLVGEGPSVL 1347



 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 69/262 (26%), Positives = 121/262 (46%), Gaps = 36/262 (13%)

Query: 794  AALRFPPIRANHSLDVSFYFRTSAPSGVFLENMG-------GPYCQWRRP-YVRVELNTS 845
            A +  P   A  +  +S  FRT+ P+G+ L + G       G +   +R  Y  +EL   
Sbjct: 502  AFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDG 561

Query: 846  RDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHR--PWVLRP--- 900
              +    D+G+G   L   S   + ND EW  V  + + ++  + V+ R  P++      
Sbjct: 562  H-LYLLLDMGSGGIKLRASSR--KVNDGEWCHVDFQRDGRKGSISVNSRSTPFLATGDSE 618

Query: 901  -MPLQTYIWM-------EYDQPL--YVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANA- 949
             + L++ +++         D PL   V +A L R  +VGC+R + ++G + +L G A A 
Sbjct: 619  ILDLESELYLGGLPEGGRVDLPLPPEVWTAAL-RAGYVGCVRDLFIDGRSRDLRGLAEAQ 677

Query: 950  -SEGTSPNCTGH----CAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGF-F 1003
             + G +P C+      CA    PC +GG C E ++ + CDC  T F G  C  +     +
Sbjct: 678  GAVGVAPFCSRETLKQCASA--PCRNGGVCREGWNRFICDCIGTGFLGRVCEREATVLSY 735

Query: 1004 EPGTWMRYNLQSALRSAAREFS 1025
            +   +M+  L +A+ + A + S
Sbjct: 736  DGSMYMKIMLPNAMHTEAEDVS 757



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 44/182 (24%), Positives = 72/182 (39%), Gaps = 13/182 (7%)

Query: 153 WNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLL 212
           W P     L L L     +AD L F G      R+ R    +     +FS +T     LL
Sbjct: 7   WRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTNATRALL 66

Query: 213 LHAE-GAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRF 271
           L+ + G   D++ L L    L L  +L  +  +P     T+     + D  WH V + R 
Sbjct: 67  LYLDDGGDCDFLELLLVDGRLRLRFTLSCA--EP----ATLQLDTPVADDRWHMVLLTRD 120

Query: 272 GRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAAR------KNLAYRHNFRGCIE 325
            R     +DG  +   +      + + +++F+GG+    R        + Y   FRG + 
Sbjct: 121 ARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLA 180

Query: 326 NV 327
           N+
Sbjct: 181 NL 182



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 56/231 (24%), Positives = 88/231 (38%), Gaps = 21/231 (9%)

Query: 385 VSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLNDGFW 444
           +SF  RT     LLL+   G     +EL L +G++ +    S  +         + D  W
Sbjct: 53  LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRW 112

Query: 445 HEVNFVAQENHAVISID-DVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTA- 502
           H V          +++D +   AEVR S    ++  +  F GG P P  R    +  T  
Sbjct: 113 HMVLLTRDARRTALAVDGEARAAEVR-SKRREMQVASDLFVGGIP-PDVRLSALTLSTVK 170

Query: 503 ----FHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSP--NMCEHDGRC- 555
               F G +  LK+  +   L   +G R G  A+ L         C+P  N C + G C 
Sbjct: 171 YEPPFRGLLANLKLGERPPALLGSQGLR-GATADPL---------CAPARNPCANGGLCT 220

Query: 556 YQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSG 606
             +  +  C C  TG+ G+ C    +     A+       G+      G+G
Sbjct: 221 VLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAG 271



 Score = 40.4 bits (93), Expect = 0.012
 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 1083 EVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLG-TSPYVYQLTTRPVTDG 1141
            E+SFS  T++  A+LLY+          L+  DG L+LR+ L    P   QL T PV D 
Sbjct: 52   ELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDT-PVADD 110

Query: 1142 QPHSINITRVYRNLFIQVD 1160
            + H + +TR  R   + VD
Sbjct: 111  RWHMVLLTRDARRTALAVD 129



 Score = 40.4 bits (93), Expect = 0.012
 Identities = 92/413 (22%), Positives = 147/413 (35%), Gaps = 76/413 (18%)

Query: 872  DDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSAELKRR------ 925
            DD WH+V    + ++  L VD           +  + +  D  L+VG      R      
Sbjct: 109  DDRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASD--LFVGGIPPDVRLSALTL 166

Query: 926  -------PFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRC-VER 977
                   PF G L  ++L      L G       T+      CA  R PC +GG C V  
Sbjct: 167  STVKYEPPFRGLLANLKLGERPPALLGSQGLRGATADPL---CAPARNPCANGGLCTVLA 223

Query: 978  YSYYTCDCDLTAFDGPYCNHDIGGFFEPG-TWMRYNLQSALRS---AAREFSHMLSRPVP 1033
                 CDC  T F G +C+ +      P    +   + S L S   A R  +  + +P  
Sbjct: 224  PGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAGRGGAGDVHQPTK 283

Query: 1034 GYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSA 1093
            G E           +V  + G  +   D             P+ + T +E++ +F T   
Sbjct: 284  GKEE----------FVATFKGNEFFCYDLS---------HNPIQSST-DEITLAFRTLQR 323

Query: 1094 PAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPV----TDGQPHSINIT 1149
              ++L+      DY+ + +K  G + L   LG+    ++    PV     D   H + +T
Sbjct: 324  NGLMLHTGKSA-DYVNLSLK-SGAVWLVINLGSG--AFEALVEPVNGKFNDNAWHDVRVT 379

Query: 1150 RVYRN---------------LFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVI 1194
            R  R                + I VD   LT   ++    + L S    Y+G    T  +
Sbjct: 380  RNLRQHAGIGHAMVNKLHYLVTISVDGI-LTTTGYTQEDYTMLGSDDFFYIGGSPNTADL 438

Query: 1195 DPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAE-ALRVQGELS 1246
                   N   F GCL  V + N       F+      A+  +  +++QG+LS
Sbjct: 439  PGSPVSNN---FMGCLKDVVYKN-----NDFKLELSRLAKEGDPKMKLQGDLS 483


>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
          Length = 1061

 Score =  115 bits (288), Expect = 3e-25
 Identities = 108/422 (25%), Positives = 184/422 (43%), Gaps = 22/422 (5%)

Query: 168 CPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQG-DYVTLE 226
           C  +A IL +DG   +    P  +     DV +F F ++   GLL+        D + LE
Sbjct: 306 CEREASILSYDGSMYMKIIMPMVMHTEAEDV-SFRFMSQRAYGLLVATTSRDSADTLRLE 364

Query: 227 LEGAHLLLHMSLGSSPIQ--PRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQ 284
           L+G  + L ++L    I      G  T+ AG  LND  WH VRV R G+ +  T+D  V 
Sbjct: 365 LDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVA 424

Query: 285 RFILNGDFERL---NLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRR 341
              + GD  RL   N++T     G++   R       +F G +++++FN +   DL   +
Sbjct: 425 EGTMVGDHTRLEFHNIET-----GIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLC--K 477

Query: 342 HSRITF-EGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLF 400
           +  I + E K  F   + +  P+ F    +++ +        + + F+F+T    G +LF
Sbjct: 478 NGDIDYCELKARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILF 537

Query: 401 SRLGDGLGHVELTLSEGQVN-VSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHA-VI 458
           +  GDG   + + L +G ++ V    +G   ++  +   LND  WH V      ++   +
Sbjct: 538 NS-GDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSL 596

Query: 459 SIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWD-CHSNQTAFHGCMELLKVDGQLV 517
            +D     +V      L   G  Y  G      S      +++  F GC+  + ++G+L 
Sbjct: 597 KVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLP 656

Query: 518 NLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCH 577
           +L      R G   ++     G +  C  + C + G C Q W+ F C C +T Y G  C+
Sbjct: 657 DLINDALHRSG---QIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCN 713

Query: 578 TP 579
            P
Sbjct: 714 DP 715



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 74/320 (23%), Positives = 127/320 (39%), Gaps = 53/320 (16%)

Query: 295 LNLDTEMFIGGLVGAAR-KNLAYRHNFRGCIENVIFN----RVNIADLAVRRHSRITFEG 349
           L  D   ++GG    A        +NF GC++ V++     R+ ++ LA    +++   G
Sbjct: 2   LGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYG 61

Query: 350 KVAFRCLDPVP-HPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSR------ 402
           +V F+C +     PINF  P  ++ +P +  +   ++SF FRT +  GL+LF+       
Sbjct: 62  EVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQER 121

Query: 403 -----------------LGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLNDGFWH 445
                            L DG  ++ L +  G + V   Q            + NDG W+
Sbjct: 122 KDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQK-----------KANDGEWY 170

Query: 446 EVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPK-------PASRWDCHS 498
            V+         IS++             ++      + GG P+       P   W    
Sbjct: 171 HVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAML 230

Query: 499 NQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCG--ITDRCSPNMCEHDGRCY 556
           N   + GC+  L +DG+  N+  +   +    A  +  +C      +C    C+++  C 
Sbjct: 231 NY-GYVGCIRDLFIDGRSKNIRQLAEMQ---NAAGVKSSCSRMSAKQCDSYPCKNNAVCK 286

Query: 557 QSWDDFICYCELTGYKGETC 576
             W+ FIC C  TGY G TC
Sbjct: 287 DGWNRFICDCTGTGYWGRTC 306



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 101/427 (23%), Positives = 174/427 (40%), Gaps = 97/427 (22%)

Query: 760  GDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPPIRANHSLDVSFYFRTSAP 818
            GD +    +A+F LR +         + ++F T ++ L    ++A  S+ + F F+T++P
Sbjct: 479  GDIDYCELKARFGLRNIIA-------DPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSP 531

Query: 819  SGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWH-L 877
             G  L N G         ++ VEL     + + FD+GNG  N+   + D   ND++WH +
Sbjct: 532  DGFILFNSGDG-----NDFIAVEL-VKGYIHYVFDLGNGP-NVIKGNSDRPLNDNQWHNV 584

Query: 878  VRAEINVKQARLRVDHRPWV-----LRPMPLQTYIWME-YDQPLYVGSAEL--KRRPFVG 929
            V    N     L+VD +         + + L+  ++M    Q +Y    +L   R  F G
Sbjct: 585  VITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQG 644

Query: 930  CLRAMRLNGVTLNLEGRA--------NASEGTSPNCTGHCAHPRLPCFHGGRCVERYSYY 981
            CL ++ LNG   +L   A           EG S  C          C + G C++++  +
Sbjct: 645  CLASVDLNGRLPDLINDALHRSGQIERGCEGPSTTCQEDS------CANQGVCMQQWEGF 698

Query: 982  TCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYIP 1041
            TCDC +T++ G  CN       +PG                                   
Sbjct: 699  TCDCSMTSYSGNQCN-------DPGA---------------------------------- 717

Query: 1042 GYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVS 1101
                  Y+ G  G G  L  +P   RP         +   + ++  FST+    +L+ + 
Sbjct: 718  -----TYIFGKSG-GLILYTWPANDRP---------STRSDRLAVGFSTTVKDGILVRID 762

Query: 1102 SF--VRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQV 1159
            S   + D++ + I + G + + + +GT     +    PV DG+ H +  TR   N  +QV
Sbjct: 763  SAPGLGDFLQLHI-EQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQV 821

Query: 1160 DYFPLTE 1166
            D +P+ E
Sbjct: 822  DNWPVNE 828



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 58/269 (21%), Positives = 105/269 (39%), Gaps = 38/269 (14%)

Query: 788  ISFHTGAA-LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSR 846
            I+F T  A +  P         +SF FRT+ P+G+ L   G P     R   R + NT  
Sbjct: 76   INFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQ---ERKDARSQKNTKV 132

Query: 847  D----------VVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPW 896
            D          +    D+G+G   + V +   + ND EW+ V  + + +   + V+ R  
Sbjct: 133  DFFAVELLDGNLYLLLDMGSG--TIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRT 190

Query: 897  VLRPMPLQTYIWMEYDQPLYVGSAELKRRP---------------FVGCLRAMRLNGVTL 941
                      + +E D  +Y+G     R                 +VGC+R + ++G + 
Sbjct: 191  PFTASGESEILDLEGD--MYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSK 248

Query: 942  NLEGRANASE--GTSPNCTGHCAHP--RLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNH 997
            N+   A      G   +C+   A      PC +   C + ++ + CDC  T + G  C  
Sbjct: 249  NIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCER 308

Query: 998  DIGGF-FEPGTWMRYNLQSALRSAAREFS 1025
            +     ++   +M+  +   + + A + S
Sbjct: 309  EASILSYDGSMYMKIIMPMVMHTEAEDVS 337



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 47/206 (22%), Positives = 87/206 (42%), Gaps = 37/206 (17%)

Query: 120 NSTFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDG 179
           ++ F G + E     +D+    + R  RI        G++     ++ C   A +     
Sbjct: 25  SNNFMGCLKEVVYKNNDIRLELS-RLARIADTKMKIYGEV-----VFKCENVATL----- 73

Query: 180 DDAISYRFPRG-VSRSLWDV-----FAFSFKTEEKDGLLLHAEG-------------AQG 220
            D I++  P   +S   W+       +F F+T E +GL+L   G              + 
Sbjct: 74  -DPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKV 132

Query: 221 DYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLD 280
           D+  +EL   +L L + +GS  I+ +            ND  W++V + R GR    +++
Sbjct: 133 DFFAVELLDGNLYLLLDMGSGTIKVKATQKKA------NDGEWYHVDIQRDGRSGTISVN 186

Query: 281 GYVQRFILNGDFERLNLDTEMFIGGL 306
                F  +G+ E L+L+ +M++GGL
Sbjct: 187 SRRTPFTASGESEILDLEGDMYLGGL 212



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 41/144 (28%), Positives = 66/144 (45%), Gaps = 8/144 (5%)

Query: 1080 TGEEVSFSFSTSSAPAVLLYVSSFVRDYMAV-LIKDDGTLQLRYQLGTSPYVYQLTT-RP 1137
            T   + F F T+S    +L+ S    D++AV L+K  G +   + LG  P V +  + RP
Sbjct: 518  TSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVK--GYIHYVFDLGNGPNVIKGNSDRP 575

Query: 1138 VTDGQPHSINITRVYRNLF-IQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDP 1196
            + D Q H++ ITR   N   ++VD   +T+    +     LD    LY+  + +    + 
Sbjct: 576  LNDNQWHNVVITRDNSNTHSLKVDTKVVTQ---VINGAKNLDLKGDLYMAGLAQGMYSNL 632

Query: 1197 EIQRYNTPGFSGCLSGVRFNNVAP 1220
                 +  GF GCL+ V  N   P
Sbjct: 633  PKLVASRDGFQGCLASVDLNGRLP 656



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 20/168 (11%)

Query: 197 DVFAFSFKTEEKDGLLLHAEGAQ--GDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSA 254
           D  A  F T  KDG+L+  + A   GD++ L +E   + +  ++G+  I  +   T V  
Sbjct: 743 DRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPV-- 800

Query: 255 GGVLNDQHWHYVRVDRFGRDVNFTLDGYV--QRFILNGDFERLNLDTEMFIGGLVGAARK 312
               ND  +H VR  R G +    +D +   + +         N   ++ IGG       
Sbjct: 801 ----NDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKG--- 853

Query: 313 NLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVP 360
                  F+G +  + ++ + + ++A   +  I   G V  R +  VP
Sbjct: 854 -----RLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSV--RLVGEVP 894


>gi|169184330 PREDICTED: novel protein similar to contactin associated
            protein-like 3 (CNTNAP3) [Homo sapiens]
          Length = 291

 Score =  103 bits (257), Expect = 1e-21
 Identities = 55/154 (35%), Positives = 93/154 (60%), Gaps = 4/154 (2%)

Query: 1079 VTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGT--SPYVYQLTTR 1136
            +T E ++ SF T+  P++LLYVSSF  +Y++V++ ++G+LQ+RY+L    +P  +    +
Sbjct: 40   LTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFK 99

Query: 1137 PVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDP 1196
             + DGQ H + I R    + ++V+     +++  L   ++ ++ K+L LG+V+E    DP
Sbjct: 100  NMADGQLHQVKINREEAVVMVEVNQS--AKKQVILSSGTEFNAVKSLILGKVLEAAGADP 157

Query: 1197 EIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRP 1230
            + +R  T GF+GCLS VRF   APLK   R   P
Sbjct: 158  DTRRAATSGFTGCLSAVRFGCAAPLKAALRPSGP 191


>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
            sapiens]
          Length = 2923

 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 115/483 (23%), Positives = 173/483 (35%), Gaps = 110/483 (22%)

Query: 189  RGVSRSLWDVFAFSFKTEEKDGLLLHAE--GAQGDYVTLELEGAHLLLHMSLGSSPIQPR 246
            RG+ +      A SF T+E+DGLLL+      + D+V LE+    + L  S G S     
Sbjct: 1381 RGLRQRFHFTLALSFATKERDGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGEST---- 1436

Query: 247  PGHTTVSA---GGVLNDQHWHYVRVDRFGRDVN----------------FTLDGYVQRFI 287
               TTVS    GGV +D  WH V++  + + +                  T+DG      
Sbjct: 1437 ---TTVSPFVPGGV-SDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVTVDGCDTGVA 1492

Query: 288  LN-----------------GDFERLNLDTEMFIGGLVGAARKNLAYRHNFRGCIEN--VI 328
            L                  G  + L+L   + +GG+             F GC+ N  V 
Sbjct: 1493 LRFGSVLGNYSCAAQGTQGGSKKSLDLTGPLLLGGVPDLPESFPVRMRQFVGCMRNLQVD 1552

Query: 329  FNRVNIADLAVRR-------------HSRITFEGKV------AFRCLDPVPHPINFGG-- 367
               +++AD                   S     G        AF C      P+ FGG  
Sbjct: 1553 SRHIDMADFIANNGTVPGCPAKKNVCDSNTCHNGGTCVNQWDAFSC----ECPLGFGGKS 1608

Query: 368  -------PHNFVQVP-------GFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELT 413
                   P +F+            P      +S  FRT    G+LL   +  G   + L 
Sbjct: 1609 CAQEMANPQHFLGSSLVAWHGLSLPISQPWYLSLMFRTRQADGVLL-QAITRGRSTITLQ 1667

Query: 414  LSEGQVNVSIAQSGRK--KLQFAAGYRLNDGFWHEVNFVAQEN----HAVISID-DVEGA 466
            L EG V +S+  +G +   L+   G R NDG WH        +    HA++S D   + A
Sbjct: 1668 LREGHVMLSVEGTGLQASSLRLEPG-RANDGDWHHAQLALGASGGPGHAILSFDYGQQRA 1726

Query: 467  EVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVE--- 523
            E  +   L     ++   GG P PA           F GC++ ++V      +  ++   
Sbjct: 1727 EGNLGPRLHGLHLSNITVGGIPGPAG-----GVARGFRGCLQGVRVSDTPEGVNSLDPSH 1781

Query: 524  GRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKE 583
            G  +      +   C + D C  N C  +  C   WD + C C+  GY G+ C       
Sbjct: 1782 GESIN-----VEQGCSLPDPCDSNPCPANSYCSNDWDSYSCSCD-PGYYGDNCTNVCDLN 1835

Query: 584  SCE 586
             CE
Sbjct: 1836 PCE 1838



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 61/248 (24%), Positives = 96/248 (38%), Gaps = 53/248 (21%)

Query: 369  HNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFS-RLGDGLGHVELTLSEGQVNV--SIAQ 425
            H+F+   G  +R    ++  F T +  GLLL++ R  +    V L + + QV +  S  +
Sbjct: 1375 HSFITFRGLRQRFHFTLALSFATKERDGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGE 1434

Query: 426  SGRKKLQFAAGYRLNDGFWHEVNF----------------VAQENHAVISIDDVE-GAEV 468
            S      F  G  ++DG WH V                   +++  AV+++D  + G  +
Sbjct: 1435 STTTVSPFVPG-GVSDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVTVDGCDTGVAL 1493

Query: 469  RVSYPL-----------------LIRTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLK 511
            R    L                 L  TG     GG P     +     Q  F GCM  L+
Sbjct: 1494 RFGSVLGNYSCAAQGTQGGSKKSLDLTG-PLLLGGVPDLPESFPVRMRQ--FVGCMRNLQ 1550

Query: 512  VDGQLVNLT---LVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCEL 568
            VD + +++       G   G  A+         + C  N C + G C   WD F C C L
Sbjct: 1551 VDSRHIDMADFIANNGTVPGCPAK--------KNVCDSNTCHNGGTCVNQWDAFSCECPL 1602

Query: 569  TGYKGETC 576
             G+ G++C
Sbjct: 1603 -GFGGKSC 1609



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 3/82 (3%)

Query: 919  SAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHC-AHPRLPCFHGGRCVER 977
            S  ++ R FVGC+R ++++   +++     A+ GT P C           C +GG CV +
Sbjct: 1534 SFPVRMRQFVGCMRNLQVDSRHIDMADFI-ANNGTVPGCPAKKNVCDSNTCHNGGTCVNQ 1592

Query: 978  YSYYTCDCDLTAFDGPYCNHDI 999
            +  ++C+C L  F G  C  ++
Sbjct: 1593 WDAFSCECPL-GFGGKSCAQEM 1613


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 109/489 (22%), Positives = 186/489 (38%), Gaps = 118/489 (24%)

Query: 189  RGVSRSLWDVFAFSFKTEEKDGLLLHAE--GAQGDYVTLELEGAHLLLHMSLGSSPIQPR 246
            RG+ +      + +F T+E++GLLL+      + D++ LE+    + L  S G +     
Sbjct: 1456 RGLRQRFHFTISLTFATQERNGLLLYNGRFNEKHDFIALEIVDEQVQLTFSAGETTTTVA 1515

Query: 247  PGHTTVSAGGVLNDQHWHYVRVD-----------------------------------RF 271
            P    V +G  ++D  WH V+V                                    RF
Sbjct: 1516 P---KVPSG--VSDGRWHSVQVQYYNKPNIGHLGLPHGPSGEKMAVVTVDDCDTTMAVRF 1570

Query: 272  GRDV-NFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFN 330
            G+D+ N++      +    G  + L+L   + +GG+         +   F GC+ N+  +
Sbjct: 1571 GKDIGNYSCAAQGTQ---TGSKKSLDLTGPLLLGGVPNLPEDFPVHNRQFVGCMRNLSVD 1627

Query: 331  RVNIADLAVRRHSRITFEGKVAFR---------------------------------CLD 357
              N+ D+A    +  T EG  A R                                 C  
Sbjct: 1628 GKNV-DMAGFIANNGTREGCAARRNFCDGRRCQNGGTCVNRWNMYLCECPLRFGGKNCEQ 1686

Query: 358  PVPHPINFGGP--------HNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGH 409
             +PHP  F G         +  + VP +     L + FR R  D   L+  +  G     
Sbjct: 1687 AMPHPQLFSGESVVSWSDLNIIISVPWY-----LGLMFRTRKEDSV-LMEATSGGPTSFR 1740

Query: 410  VELTLSEGQVNVSIAQSGRKKLQFAAGYRLNDGFWH----EVNFVAQENH----AVISID 461
            +++  +  Q  VS   S  + +  + G R+ DG WH    E+  V +++       +++D
Sbjct: 1741 LQILNNYLQFEVSHGPSDVESVMLS-GLRVTDGEWHHLLIELKNVKEDSEMKHLVTMTLD 1799

Query: 462  ---DVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVN 518
               D   A++    P L  T  S   GG  +     D  S +  F GCM+ +++ G   N
Sbjct: 1800 YGMDQNKADIGGMLPGL--TVRSVVVGGASE-----DKVSVRRGFRGCMQGVRMGGTPTN 1852

Query: 519  L-TLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCH 577
            + TL     L    +   D C + D C+ + C  + RC+ +W+D+ C C+  GY G  C 
Sbjct: 1853 VATLNMNNALKVRVK---DGCDVDDPCTSSPCPPNSRCHDAWEDYSCVCD-KGYLGINCV 1908

Query: 578  TPLYKESCE 586
               +   CE
Sbjct: 1909 DACHLNPCE 1917



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 65/256 (25%), Positives = 98/256 (38%), Gaps = 67/256 (26%)

Query: 368  PHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLL----FSRLGDGLG------HVELTLSEG 417
            P +FV   G  +R    +S  F T +  GLLL    F+   D +        V+LT S G
Sbjct: 1449 PQSFVTFRGLRQRFHFTISLTFATQERNGLLLYNGRFNEKHDFIALEIVDEQVQLTFSAG 1508

Query: 418  QVNVSIAQSGRKKLQFAAGYRLNDGFWHEVNF----------------VAQENHAVISID 461
            +   ++A       +  +G  ++DG WH V                   + E  AV+++D
Sbjct: 1509 ETTTTVAP------KVPSG--VSDGRWHSVQVQYYNKPNIGHLGLPHGPSGEKMAVVTVD 1560

Query: 462  DVE-------GAEV-----------RVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTAF 503
            D +       G ++             S   L  TG     GG P     +  H+ Q  F
Sbjct: 1561 DCDTTMAVRFGKDIGNYSCAAQGTQTGSKKSLDLTG-PLLLGGVPNLPEDFPVHNRQ--F 1617

Query: 504  HGCMELLKVDGQLVNLT---LVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWD 560
             GCM  L VDG+ V++       G R G  A   F        C    C++ G C   W+
Sbjct: 1618 VGCMRNLSVDGKNVDMAGFIANNGTREGCAARRNF--------CDGRRCQNGGTCVNRWN 1669

Query: 561  DFICYCELTGYKGETC 576
             ++C C L  + G+ C
Sbjct: 1670 MYLCECPLR-FGGKNC 1684



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 7/74 (9%)

Query: 925  RPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGH---CAHPRLPCFHGGRCVERYSYY 981
            R FVGC+R + ++G  +++ G   A+ GT   C      C   R  C +GG CV R++ Y
Sbjct: 1615 RQFVGCMRNLSVDGKNVDMAGFI-ANNGTREGCAARRNFCDGRR--CQNGGTCVNRWNMY 1671

Query: 982  TCDCDLTAFDGPYC 995
             C+C L  F G  C
Sbjct: 1672 LCECPL-RFGGKNC 1684



 Score = 34.7 bits (78), Expect = 0.65
 Identities = 44/187 (23%), Positives = 71/187 (37%), Gaps = 30/187 (16%)

Query: 967  PCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSH 1026
            PC   GRC  R   YTC+C    F G +C  D                       +    
Sbjct: 1371 PCGANGRCRSREGGYTCEC-FEDFTGEHCEVDA------------RSGRCANGVCKNGGT 1417

Query: 1027 MLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRG--PVYNVTGEEV 1084
             ++  + G+     PG         Y  P   +     P +    +RG    ++ T   +
Sbjct: 1418 CVNLLIGGFHCVCPPG--------EYERPYCEVTTRSFPPQSFVTFRGLRQRFHFT---I 1466

Query: 1085 SFSFSTSSAPAVLLYVSSF--VRDYMAVLIKDDGTLQLRYQLG-TSPYVYQLTTRPVTDG 1141
            S +F+T     +LLY   F    D++A+ I D+  +QL +  G T+  V       V+DG
Sbjct: 1467 SLTFATQERNGLLLYNGRFNEKHDFIALEIVDE-QVQLTFSAGETTTTVAPKVPSGVSDG 1525

Query: 1142 QPHSINI 1148
            + HS+ +
Sbjct: 1526 RWHSVQV 1532



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 19/68 (27%), Positives = 28/68 (41%), Gaps = 7/68 (10%)

Query: 924  RRPFVGCLRAMRLNGV-----TLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERY 978
            RR F GC++ +R+ G      TLN+            +    C     PC    RC + +
Sbjct: 1834 RRGFRGCMQGVRMGGTPTNVATLNMNNALKVRVKDGCDVDDPCTSS--PCPPNSRCHDAW 1891

Query: 979  SYYTCDCD 986
              Y+C CD
Sbjct: 1892 EDYSCVCD 1899


>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
          Length = 3075

 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 86/324 (26%), Positives = 129/324 (39%), Gaps = 37/324 (11%)

Query: 202  SFKTEEKDGLLLH-AEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLND 260
            S +T    GL+ + A   Q DY  L+L G  L     LG        G T VS   +L+D
Sbjct: 2742 SIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGK-------GRTKVSHPALLSD 2794

Query: 261  QHWHYVRVDRFGRDVNFTLDGYVQRFI-LNGDFERLNLDTEMFIGGLVG--AARKNLAYR 317
              WH V+ D   R    T+DG     + + GD   L+++   ++GGL     ARK     
Sbjct: 2795 GKWHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNIT 2854

Query: 318  HNFRGCIENVIFNRVNI-ADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQV-P 375
            H+   CI +V  N   +  D  V   S  T       RC         F G      V  
Sbjct: 2855 HSIPACIGDVTVNSKQLDKDSPV---SAFTVN-----RCYAVAQEGTYFDGSGYAALVKE 2906

Query: 376  GFPRRGRLAVSFRFRTWDLTGLLL--FSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQF 433
            G+  +  + ++  FRT    G+LL   +   D +G   L L +G+V   +     +    
Sbjct: 2907 GYKVQSDVNITLEFRTSSQNGVLLGISTAKVDAIG---LELVDGKVLFHVNNGAGR---I 2960

Query: 434  AAGYR------LNDGFWHEVNFVAQENHAVISID-DVEGAEVRVSYPLLIRTGTSYFFGG 486
             A Y       L DG WH +     ++   + +D +  GAE   +    + T    + GG
Sbjct: 2961 TAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGG 3020

Query: 487  CPKPASRWDCHSNQTAFHGCMELL 510
             P    +  C  +QT+F GC+  L
Sbjct: 3021 YPAGVKQ-KCLRSQTSFRGCLRKL 3043



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 64/286 (22%), Positives = 108/286 (37%), Gaps = 28/286 (9%)

Query: 191  VSRSLWDVFAFSFKTEEKDGLLLH-AEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGH 249
            +S + ++    + KT+E D LL +       D++ +E+    +     LGS       G 
Sbjct: 2134 ISSTNYNTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGS-------GS 2186

Query: 250  TTVSAGGV-LNDQHWHYVRVDRFGR---------DVNFTLDGYVQRFILNGDFERLNLDT 299
            T +      ++D  WH + V RFG            N        +     +   +N  T
Sbjct: 2187 TRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDVNNST 2246

Query: 300  EMFIGGLVGAARKNLAYR-HNFRGCIENVIFNRVNIADLAVRRHSRITFEGKV--AFRCL 356
             MF+GGL G  +K+ A +  +F+GC+     N  +I        + I  EGK    F   
Sbjct: 2247 LMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIG-----LWNYIEREGKCRGCFGSS 2301

Query: 357  DPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSE 416
                   +F G    V     P      +   F T+   GLLL+         + + L  
Sbjct: 2302 QNEDPSFHFDGSGYSVVEKSLPATVTQIIML-FNTFSPNGLLLYLGSYGTKDFLSIELFR 2360

Query: 417  GQVNVSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDD 462
            G+V V +   G   +      R N+G W+++ F       V+++ D
Sbjct: 2361 GRVKV-MTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVID 2405



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 96/426 (22%), Positives = 180/426 (42%), Gaps = 67/426 (15%)

Query: 153  WNPRGKIGLRLGLYGCPYKAD-ILYFDGD--DAISYRFPRGVSRSLWDVFAFSFKTEEKD 209
            WN   + G   G +G     D   +FDG     +    P  V++ +       F T   +
Sbjct: 2285 WNYIEREGKCRGCFGSSQNEDPSFHFDGSGYSVVEKSLPATVTQII-----MLFNTFSPN 2339

Query: 210  GLLLHAEGAQG--DYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVR 267
            GLLL+  G+ G  D++++EL    + +   LGS PI       T+      N+  W+ + 
Sbjct: 2340 GLLLYL-GSYGTKDFLSIELFRGRVKVMTDLGSGPI-------TLLTDRRYNNGTWYKIA 2391

Query: 268  VDRFGRD-VNFTLDGYV---------QRFILNGDFERLNLDTEMFIGGLVGA--ARKNLA 315
              R  +  V   +D Y          +    + D  RL+ D  +++GGL  +   R+ + 
Sbjct: 2392 FQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKDP-IYVGGLPRSRVVRRGVT 2450

Query: 316  YRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINF--GGPHNFVQ 373
             + +F GCI+N+  +R   +   + R+S    +G +    L+P+   ++F  GG   +++
Sbjct: 2451 TK-SFVGCIKNLEISR---STFDLLRNSYGVRKGCL----LEPI-RSVSFLKGG---YIE 2498

Query: 374  VPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGD-------GLGHV---ELTLSEGQVNVSI 423
            +P             F T + +G++L +  GD          HV    + L  G + V +
Sbjct: 2499 LPPKSLSPESEWLVTFATTNSSGIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHV 2558

Query: 424  AQSG----RKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRT- 478
                    RK L  A     +DG  H ++ V       + +D+    E+++   +  RT 
Sbjct: 2559 NPGDGTGLRKALLHAPTGTCSDGQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTI 2618

Query: 479  -GTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDT 537
              ++ + GG P+        + + +FHGC++ L     + NL L++      + +V  DT
Sbjct: 2619 NVSNLYVGGIPE-GEGTSLLTMRRSFHGCIKNL-----IFNLELLDFNSAVGHEQVDLDT 2672

Query: 538  CGITDR 543
            C +++R
Sbjct: 2673 CWLSER 2678



 Score = 39.3 bits (90), Expect = 0.026
 Identities = 27/83 (32%), Positives = 42/83 (50%), Gaps = 5/83 (6%)

Query: 1135 TRPVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVME-TGV 1193
            T   +DGQ HSI++ R  R + +Q+D     E K   LV+S+  +   LY+G + E  G 
Sbjct: 2575 TGTCSDGQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGT 2634

Query: 1194 IDPEIQRYNTPGFSGCLSGVRFN 1216
                ++R     F GC+  + FN
Sbjct: 2635 SLLTMRR----SFHGCIKNLIFN 2653


>gi|10518506 coagulation factor VIII isoform b precursor [Homo
           sapiens]
          Length = 216

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 10/137 (7%)

Query: 40  ASSYYSLLTA---PRFARLH---GISGWSPRIGDPNPWLQIDLMKKHRIRAVATQG--SF 91
           ASSY++ + A   P  ARLH     + W P++ +P  WLQ+D  K  ++  V TQG  S 
Sbjct: 76  ASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSL 135

Query: 92  NSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTARYIRIVPL 151
            +  +V  +++        WT F+Q G    F GN +    V + L      RY+RI P 
Sbjct: 136 LTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQ 195

Query: 152 AWNPRGKIGLRLGLYGC 168
           +W    +I LR+ + GC
Sbjct: 196 SW--VHQIALRMEVLGC 210



 Score = 32.3 bits (72), Expect = 3.2
 Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 2/46 (4%)

Query: 123 FFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGC 168
           FFGNV+ S +  +  +    ARYIR+ P  ++ R    LR+ L GC
Sbjct: 10  FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST--LRMELMGC 53


>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
          Length = 2351

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 10/137 (7%)

Query: 40   ASSYYSLLTA---PRFARLH---GISGWSPRIGDPNPWLQIDLMKKHRIRAVATQG--SF 91
            ASSY++ + A   P  ARLH     + W P++ +P  WLQ+D  K  ++  V TQG  S 
Sbjct: 2211 ASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSL 2270

Query: 92   NSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTARYIRIVPL 151
             +  +V  +++        WT F+Q G    F GN +    V + L      RY+RI P 
Sbjct: 2271 LTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQ 2330

Query: 152  AWNPRGKIGLRLGLYGC 168
            +W    +I LR+ + GC
Sbjct: 2331 SW--VHQIALRMEVLGC 2345



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 39/129 (30%), Positives = 70/129 (54%), Gaps = 15/129 (11%)

Query: 49   APRFARLH---GISGWSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWD--WVTRYMLL 103
            AP+ ARLH    I+ WS +  +P  W+++DL+    I  + TQG+   +   ++++++++
Sbjct: 2066 APKLARLHYSGSINAWSTK--EPFSWIKVDLLAPMIIHGIKTQGARQKFSSLYISQFIIM 2123

Query: 104  YGDRVDSWTPFYQRGHNS----TFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKI 159
            Y      W  +  RG+++     FFGNV+ S +  +  +    ARYIR+ P  ++ R   
Sbjct: 2124 YSLDGKKWQTY--RGNSTGTLMVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST- 2180

Query: 160  GLRLGLYGC 168
             LR+ L GC
Sbjct: 2181 -LRMELMGC 2188


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 41/126 (32%), Positives = 66/126 (52%), Gaps = 9/126 (7%)

Query: 50   PRFARLHG---ISGWSPRIGDPNPWLQIDLMKKHRIRAVATQG--SFNSWDWVTRYMLLY 104
            P  ARL+    ++ W  +  +   WL+IDL+K  +I A+ TQG  S +S  +V  Y + Y
Sbjct: 2098 PFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHY 2157

Query: 105  GDRVDSWTPFYQRGH--NSTFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLR 162
             ++   W P+  +    +  F GN N    V++  +    +R+IR++P  WN    I LR
Sbjct: 2158 SEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQ--SIALR 2215

Query: 163  LGLYGC 168
            L L+GC
Sbjct: 2216 LELFGC 2221



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 43/134 (32%), Positives = 62/134 (46%), Gaps = 21/134 (15%)

Query: 50   PRFARLHG---ISGWSPRI----GDPNPWLQIDLMKKHRIRAVATQGS--FNSWDWVTRY 100
            PR ARL+     + WS           PW+Q+D+ K+  I  + TQG+  +    + T +
Sbjct: 1934 PRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGIQTQGAKHYLKSCYTTEF 1993

Query: 101  MLLYGDRVDSWTPFYQRGHNST-----FFGNVNESAVVRHDLHFHFTARYIRIVPL-AWN 154
             + Y     +W  F  +G NST     F GN + S +  +       ARYIRI P  A+N
Sbjct: 1994 YVAYSSNQINWQIF--KG-NSTRNVMYFNGNSDASTIKENQFDPPIVARYIRISPTRAYN 2050

Query: 155  PRGKIGLRLGLYGC 168
               +  LRL L GC
Sbjct: 2051 ---RPTLRLELQGC 2061


>gi|10835083 X-linked juvenile retinoschisis protein precursor [Homo
           sapiens]
          Length = 224

 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 45/134 (33%), Positives = 73/134 (54%), Gaps = 8/134 (5%)

Query: 43  YYSLLTAPRFARLHGIS---GWSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTR 99
           +YS  TA + ARL+       W  +  D + WLQIDL +   I  + TQG  +  +W+T+
Sbjct: 92  WYSSWTANK-ARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQGRCDIDEWMTK 150

Query: 100 YMLLYG-DRVDSWTPFY-QRGHNSTFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRG 157
           Y + Y  D   +W  +  Q G+N  F+GN + ++ V++ L     +R+IR++PL W+ R 
Sbjct: 151 YSVQYRTDERLNWIYYKDQTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVR- 209

Query: 158 KIGLRLGLYGCPYK 171
            I +R+ L  C  K
Sbjct: 210 -IAIRMELLECVSK 222


>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
           sapiens]
          Length = 756

 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 35/111 (31%), Positives = 52/111 (46%), Gaps = 2/111 (1%)

Query: 61  WSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSW--DWVTRYMLLYGDRVDSWTPFYQRG 118
           W     D   W+++D  +  R   V TQG  + W  DWVT Y ++  +   +W       
Sbjct: 184 WCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGS 243

Query: 119 HNSTFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCP 169
            +  F GN  +   V ++L     ARYIRI P +W   G I +R+ + GCP
Sbjct: 244 GDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCP 294


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 112/466 (24%), Positives = 184/466 (39%), Gaps = 73/466 (15%)

Query: 793  GAALRFPPI-RANHSLDVSFYFRTSAPSGVFLENMG--GPYCQWRRPYVRVELNTSRDVV 849
            G+ L  P +   +H L +   F+  AP GV L + G  GP       +V + +     + 
Sbjct: 3936 GSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGKSGPV----EDFVSLAM-VGGHLE 3990

Query: 850  FAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMP------- 902
            F +++G+G   L V           WH V AE   K   LRV+    VLR  P       
Sbjct: 3991 FRYELGSG---LAVLRSAEPLALGRWHRVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLN 4047

Query: 903  LQTYIWMEYDQP-LYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHC 961
            L T +++   +P + +  A      F GC+  + +NG  L+L      S+G    C    
Sbjct: 4048 LHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIG-QCYDSS 4106

Query: 962  AHPRLPCFHGGRCVERYSY-YTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSA 1020
               R PC HG  C+    Y + C C    F G  C H+     E    +R   +  L   
Sbjct: 4107 PCERQPCQHGATCMPAGEYEFQCLC-RDGFKGDLCEHE-----ENPCQLR---EPCLHGG 4157

Query: 1021 AREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDY---PRPGRPVPGYRGPVY 1077
              + +  L           +PG+  P    G  G G    D+      G   PG  G  +
Sbjct: 4158 TCQGTRCLC----------LPGFSGPRCQQG-SGHGIAESDWHLEGSGGNDAPGQYGAYF 4206

Query: 1078 NVTG-----------------EEVSFSFSTSSAPAVLLYVSSFV------RDYMAVLIKD 1114
            +  G                 E +     TS+A  +LL+    V      +D++++ ++ 
Sbjct: 4207 HDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQ- 4265

Query: 1115 DGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVD 1174
            DG L  RYQLG S     ++  P+ DG+ H +   R  R   IQVD   L   + S   +
Sbjct: 4266 DGHLVFRYQLG-SGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGR-SPGPN 4323

Query: 1175 SQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNVAP 1220
              +++  ++Y+G   +   +     R+++ G +GC+  +  ++  P
Sbjct: 4324 VAVNAKGSVYIGGAPDVATLTG--GRFSS-GITGCVKNLVLHSARP 4366



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 41/136 (30%), Positives = 63/136 (46%), Gaps = 17/136 (12%)

Query: 203  FKTEEKDGLLLHAEGAQG---DYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLN 259
            FK    DG+LL + G  G   D+V+L + G HL     LGS       G   + +   L 
Sbjct: 3957 FKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGS-------GLAVLRSAEPLA 4009

Query: 260  DQHWHYVRVDRFGRDVNFTLDGYVQRFILN---GDFERLNLDTEMFIGGLVGAARKNLA- 315
               WH V  +R  +D +  ++G   R +L    G  + LNL T +++GG+  +   + A 
Sbjct: 4010 LGRWHRVSAERLNKDGSLRVNG--GRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPAT 4067

Query: 316  -YRHNFRGCIENVIFN 330
                +FRGC+  V  N
Sbjct: 4068 NMSAHFRGCVGEVSVN 4083



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 25/169 (14%)

Query: 176  YFDGDDAISYRFPRGV-SRSLWDV---FAFSFKTEEKDGLLLH-----AEGAQG-DYVTL 225
            YF  D  ++  FP  V SRSL +V        +T    GLLL       E  QG D+++L
Sbjct: 4205 YFHDDGFLA--FPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISL 4262

Query: 226  ELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQR 285
             L+  HL+    LGS       G   + +   +ND  WH V   R GR  +  +DG  + 
Sbjct: 4263 GLQDGHLVFRYQLGS-------GEARLVSEDPINDGEWHRVTALREGRRGSIQVDG--EE 4313

Query: 286  FILN---GDFERLNLDTEMFIGGLVGAAR-KNLAYRHNFRGCIENVIFN 330
             +     G    +N    ++IGG    A      +     GC++N++ +
Sbjct: 4314 LVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLH 4362



 Score = 37.7 bits (86), Expect = 0.077
 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 7/114 (6%)

Query: 385  VSFRFRTWDLTGLLLFSRL-----GDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRL 439
            +    RT   +GLLL+  +     G G   + L L +G + V   Q G  + +  +   +
Sbjct: 4230 IELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHL-VFRYQLGSGEARLVSEDPI 4288

Query: 440  NDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYP-LLIRTGTSYFFGGCPKPAS 492
            NDG WH V  + +     I +D  E    R   P + +    S + GG P  A+
Sbjct: 4289 NDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVAT 4342



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 8/73 (10%)

Query: 927  FVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPR-LPCFHGGRCVE-RYSYYTCD 984
            F+GC+R +R+ G  +        + G S     HC   R  PC +GG+C +   S Y C 
Sbjct: 3816 FIGCVRELRIQGEEIVFHDLNLTAHGIS-----HCPTCRDRPCQNGGQCHDSESSSYVCV 3870

Query: 985  CDLTAFDGPYCNH 997
            C    F G  C H
Sbjct: 3871 CP-AGFTGSRCEH 3882



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 47/188 (25%), Positives = 76/188 (40%), Gaps = 27/188 (14%)

Query: 790  FHTGAALRFPPIRANHSLD-----VSFYFRTSAPSGVFL-ENMGGPYCQWRRPYVRVELN 843
            FH    L FP    + SL      +    RTS  SG+ L + +        + ++ + L 
Sbjct: 4206 FHDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQ 4265

Query: 844  TSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPL 903
                +VF + +G+G+  L   S+D   ND EWH V A    ++  ++VD    V    P 
Sbjct: 4266 DGH-LVFRYQLGSGEARLV--SED-PINDGEWHRVTALREGRRGSIQVDGEELVSGRSP- 4320

Query: 904  QTYIWMEYDQPLYVGS----AELKRRPF----VGCLRAMRLNGV--------TLNLEGRA 947
               + +     +Y+G     A L    F     GC++ + L+           L+L+ RA
Sbjct: 4321 GPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLHSARPGAPPPQPLDLQHRA 4380

Query: 948  NASEGTSP 955
             A   T P
Sbjct: 4381 QAGANTRP 4388


>gi|239758135 PREDICTED: similar to cell recognition molecule CASPR3
            [Homo sapiens]
          Length = 140

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 35/113 (30%), Positives = 68/113 (60%), Gaps = 4/113 (3%)

Query: 1079 VTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTR 1136
            +T E ++ SF T+  P++LLYVSSF  +Y++V++ ++G+LQ+RY+L    +P  +    +
Sbjct: 28   LTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFK 87

Query: 1137 PVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVM 1189
             + DGQ H + I R      + V+     +++  L   ++ ++ K+L LG+V+
Sbjct: 88   NMADGQLHQVKINR--EEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVL 138


>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
          Length = 909

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 8/144 (5%)

Query: 31  GPLYARSLGASSYYSL-LTAPRFARLHGI-SGWSPRIGDPNPWLQIDLMKKHRIRAVATQ 88
           G +    + ASS YS     P+ +RLHG  +GW+P +     +LQ+DL     + A+ATQ
Sbjct: 286 GRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQ 345

Query: 89  GSFN----SWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTAR 144
           G+ +    +  +V  Y L      + W  +    ++  F  N + + VV + LH     R
Sbjct: 346 GAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTR 405

Query: 145 YIRIVPLAWNPRGKIGLRLGLYGC 168
           ++RI P  W+    I LRL L+GC
Sbjct: 406 FVRIRPQTWH--SGIALRLELFGC 427



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 20/158 (12%)

Query: 29  LVGPLYARSLGASSYYSLLTAPRFARL-HGISGWSPRIGDPNP---WLQIDLMKKHRIRA 84
           L G +    + ASS    L +P  ARL    SGW PRI    P   WLQ+DL     ++ 
Sbjct: 441 LSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKG 500

Query: 85  VATQGS--------FNSWDWVTRYMLLYGDRVDSWTPFY--QRGHNSTFFGNVNESA--V 132
           V  QG+          +  +V ++ + Y      W      +      F GN++     +
Sbjct: 501 VIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDI 560

Query: 133 VRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPY 170
            R D      A+Y+R+ P  W+P G IG+RL + GC +
Sbjct: 561 RRFD---PIPAQYVRVYPERWSPAG-IGMRLEVLGCDW 594


>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
          Length = 901

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 8/144 (5%)

Query: 31  GPLYARSLGASSYYSL-LTAPRFARLHGI-SGWSPRIGDPNPWLQIDLMKKHRIRAVATQ 88
           G +    + ASS YS     P+ +RLHG  +GW+P +     +LQ+DL     + A+ATQ
Sbjct: 286 GRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQ 345

Query: 89  GSFN----SWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTAR 144
           G+ +    +  +V  Y L      + W  +    ++  F  N + + VV + LH     R
Sbjct: 346 GAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTR 405

Query: 145 YIRIVPLAWNPRGKIGLRLGLYGC 168
           ++RI P  W+    I LRL L+GC
Sbjct: 406 FVRIRPQTWH--SGIALRLELFGC 427



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 20/158 (12%)

Query: 29  LVGPLYARSLGASSYYSLLTAPRFARL-HGISGWSPRIGDPNP---WLQIDLMKKHRIRA 84
           L G +    + ASS    L +P  ARL    SGW PRI    P   WLQ+DL     ++ 
Sbjct: 441 LSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKG 500

Query: 85  VATQGS--------FNSWDWVTRYMLLYGDRVDSWTPFY--QRGHNSTFFGNVNESA--V 132
           V  QG+          +  +V ++ + Y      W      +      F GN++     +
Sbjct: 501 VIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDI 560

Query: 133 VRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPY 170
            R D      A+Y+R+ P  W+P G IG+RL + GC +
Sbjct: 561 RRFD---PIPAQYVRVYPERWSPAG-IGMRLEVLGCDW 594


>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
          Length = 931

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 8/144 (5%)

Query: 31  GPLYARSLGASSYYSL-LTAPRFARLHGI-SGWSPRIGDPNPWLQIDLMKKHRIRAVATQ 88
           G +    + ASS YS     P+ +RLHG  +GW+P +     +LQ+DL     + A+ATQ
Sbjct: 286 GRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQ 345

Query: 89  GSFN----SWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTAR 144
           G+ +    +  +V  Y L      + W  +    ++  F  N + + VV + LH     R
Sbjct: 346 GAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTR 405

Query: 145 YIRIVPLAWNPRGKIGLRLGLYGC 168
           ++RI P  W+    I LRL L+GC
Sbjct: 406 FVRIRPQTWH--SGIALRLELFGC 427



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 20/158 (12%)

Query: 29  LVGPLYARSLGASSYYSLLTAPRFARL-HGISGWSPRIGDPNP---WLQIDLMKKHRIRA 84
           L G +    + ASS    L +P  ARL    SGW PRI    P   WLQ+DL     ++ 
Sbjct: 441 LSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKG 500

Query: 85  VATQGS--------FNSWDWVTRYMLLYGDRVDSWTPFY--QRGHNSTFFGNVNESA--V 132
           V  QG+          +  +V ++ + Y      W      +      F GN++     +
Sbjct: 501 VIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDI 560

Query: 133 VRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPY 170
            R D      A+Y+R+ P  W+P G IG+RL + GC +
Sbjct: 561 RRFD---PIPAQYVRVYPERWSPAG-IGMRLEVLGCDW 594


>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
          Length = 555

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 8/144 (5%)

Query: 31  GPLYARSLGASSYYSL-LTAPRFARLHGI-SGWSPRIGDPNPWLQIDLMKKHRIRAVATQ 88
           G +    + ASS YS     P+ +RLHG  +GW+P +     +LQ+DL     + A+ATQ
Sbjct: 286 GRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQ 345

Query: 89  GSFN----SWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTAR 144
           G+ +    +  +V  Y L      + W  +    ++  F  N + + VV + LH     R
Sbjct: 346 GAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTR 405

Query: 145 YIRIVPLAWNPRGKIGLRLGLYGC 168
           ++RI P  W+    I LRL L+GC
Sbjct: 406 FVRIRPQTWH--SGIALRLELFGC 427



 Score = 37.7 bits (86), Expect = 0.077
 Identities = 25/66 (37%), Positives = 32/66 (48%), Gaps = 4/66 (6%)

Query: 29  LVGPLYARSLGASSYYSLLTAPRFARL-HGISGWSPRIGDPNP---WLQIDLMKKHRIRA 84
           L G +    + ASS    L +P  ARL    SGW PRI    P   WLQ+DL     ++ 
Sbjct: 441 LSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKG 500

Query: 85  VATQGS 90
           V  QG+
Sbjct: 501 VIIQGA 506


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.140    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,838,427
Number of Sequences: 37866
Number of extensions: 3243804
Number of successful extensions: 30011
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 343
Number of HSP's successfully gapped in prelim test: 401
Number of HSP's that attempted gapping in prelim test: 18853
Number of HSP's gapped (non-prelim): 8197
length of query: 1384
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1269
effective length of database: 13,892,928
effective search space: 17630125632
effective search space used: 17630125632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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