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Search of human proteins with 4505389
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505389 nuclear transcription factor Y, alpha isoform 1
[Homo sapiens]
(347 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505389 nuclear transcription factor Y, alpha isoform 1 [Homo... 670 0.0
gi|11496974 nuclear transcription factor Y, alpha isoform 2 [Hom... 603 e-173
gi|217272829 nuclear transcription factor Y, gamma isoform 3 [Ho... 59 8e-09
gi|217272833 nuclear transcription factor Y, gamma isoform 4 [Ho... 56 4e-08
gi|11496978 nuclear transcription factor Y, gamma isoform 2 [Hom... 56 4e-08
gi|217272831 nuclear transcription factor Y, gamma isoform 1 [Ho... 55 1e-07
gi|217272835 nuclear transcription factor Y, gamma isoform 5 [Ho... 52 6e-07
gi|67010025 Sp4 transcription factor [Homo sapiens] 52 1e-06
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 50 2e-06
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 47 3e-05
gi|38788260 bromodomain PHD finger transcription factor isoform ... 47 3e-05
gi|38788274 bromodomain PHD finger transcription factor isoform ... 47 3e-05
gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens] 46 4e-05
gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens] 46 4e-05
gi|15812226 transcriptional regulating factor 1 [Homo sapiens] 45 1e-04
gi|221139761 zinc finger protein 853 [Homo sapiens] 45 1e-04
gi|19923559 EMSY protein [Homo sapiens] 44 2e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 44 2e-04
gi|56549696 E1A binding protein p400 [Homo sapiens] 43 4e-04
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 43 4e-04
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 43 4e-04
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 43 4e-04
gi|38372901 Sp1 transcription factor isoform a [Homo sapiens] 42 6e-04
gi|218751903 Sp1 transcription factor isoform b [Homo sapiens] 42 6e-04
gi|44890059 involucrin [Homo sapiens] 42 6e-04
gi|125625357 Sp2 transcription factor [Homo sapiens] 42 6e-04
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 41 0.001
gi|62865633 Sp3 transcription factor isoform 2 [Homo sapiens] 40 0.002
gi|38373693 Sp3 transcription factor isoform 1 [Homo sapiens] 40 0.002
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 40 0.003
>gi|4505389 nuclear transcription factor Y, alpha isoform 1 [Homo
sapiens]
Length = 347
Score = 670 bits (1729), Expect = 0.0
Identities = 347/347 (100%), Positives = 347/347 (100%)
Query: 1 MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPL 60
MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPL
Sbjct: 1 MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPL 60
Query: 61 MVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAV 120
MVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAV
Sbjct: 61 MVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAV 120
Query: 121 QVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTIL 180
QVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTIL
Sbjct: 121 QVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTIL 180
Query: 181 QQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMV 240
QQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMV
Sbjct: 181 QQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMV 240
Query: 241 PGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLH 300
PGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLH
Sbjct: 241 PGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLH 300
Query: 301 ESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS 347
ESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS
Sbjct: 301 ESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS 347
>gi|11496974 nuclear transcription factor Y, alpha isoform 2 [Homo
sapiens]
Length = 318
Score = 603 bits (1554), Expect = e-173
Identities = 318/347 (91%), Positives = 318/347 (91%), Gaps = 29/347 (8%)
Query: 1 MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPL 60
MEQYTANSNSSTEQIVVQAGQIQQQ VQGQPL
Sbjct: 1 MEQYTANSNSSTEQIVVQAGQIQQQ-----------------------------VQGQPL 31
Query: 61 MVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAV 120
MVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAV
Sbjct: 32 MVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAV 91
Query: 121 QVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTIL 180
QVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTIL
Sbjct: 92 QVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTIL 151
Query: 181 QQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMV 240
QQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMV
Sbjct: 152 QQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMV 211
Query: 241 PGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLH 300
PGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLH
Sbjct: 212 PGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLH 271
Query: 301 ESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS 347
ESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS
Sbjct: 272 ESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS 318
>gi|217272829 nuclear transcription factor Y, gamma isoform 3 [Homo
sapiens]
Length = 334
Score = 58.5 bits (140), Expect = 8e-09
Identities = 56/174 (32%), Positives = 78/174 (44%), Gaps = 14/174 (8%)
Query: 26 QQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPI-MVQAVPG 84
QQ VQ Q + Q ++S +Q Q++ QP Q + + GQ + +VQA P
Sbjct: 150 QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
Query: 85 GQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQP--QTAVT 142
GQ Q Q +QQI + G+I Q + VQ GQ Q I + QP T V
Sbjct: 210 GQAQQAQSGTGQTMQVMQQI-ITNTGEI-----QQIPVQLNAGQLQYIRLAQPVSGTQVV 263
Query: 143 AGQTQTQQQIAVQGQQVAQT--AEGQTIVYQPVNADGTILQQVTVPVSGMITIP 194
GQ QT +A QQ+ QT +GQ Q + +QQVT+P + P
Sbjct: 264 QGQIQT---LATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMPAGQDLAQP 314
Score = 49.7 bits (117), Expect = 4e-06
Identities = 54/194 (27%), Positives = 79/194 (40%), Gaps = 34/194 (17%)
Query: 89 TIMQVPVS-GTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQ------------QIIIQ 135
T+ Q P + QG QQ Q IQ GQ + Q QQGQT QI+
Sbjct: 147 TLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQA 206
Query: 136 QPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPA 195
QPQ Q+ T Q + V Q + T E Q I PV + LQ + + A
Sbjct: 207 QPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQI---PVQLNAGQLQYIRL---------A 254
Query: 196 ASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLP 255
++G Q+VQ T T++ Q T T V G G + IQ++ +P
Sbjct: 255 QPVSGTQVVQGQIQTLATNAQQITQT--------EVQQGQQQFSQFTDGQLYQIQQVTMP 306
Query: 256 GAEMLEEEPLYVNA 269
+ L +P+++ +
Sbjct: 307 AGQDL-AQPMFIQS 319
Score = 32.7 bits (73), Expect = 0.49
Identities = 40/130 (30%), Positives = 51/130 (39%), Gaps = 28/130 (21%)
Query: 1 MEQYTANSNSSTEQIVVQ--AGQIQQ----QQQGGVTAVQLQTEAQVASASGQQVQTLQV 54
M+Q N+ +QI VQ AGQ+Q Q G VQ Q Q + + QQ+ +V
Sbjct: 226 MQQIITNTGE-IQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQI--QTLATNAQQITQTEV 282
Query: 55 VQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQI 114
QGQ Q + GQL I QV + Q L Q + Q
Sbjct: 283 QQGQQQFSQFTDGQL------------------YQIQQVTMPAGQDLAQPMFIQSAN-QP 323
Query: 115 QGGQAVQVQG 124
GQA QV G
Sbjct: 324 SDGQAPQVTG 333
>gi|217272833 nuclear transcription factor Y, gamma isoform 4 [Homo
sapiens]
Length = 297
Score = 56.2 bits (134), Expect = 4e-08
Identities = 55/181 (30%), Positives = 78/181 (43%), Gaps = 27/181 (14%)
Query: 26 QQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPI-MVQAVPG 84
QQ VQ Q + Q ++S +Q Q++ QP Q + + GQ + +VQA P
Sbjct: 112 QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 171
Query: 85 GQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQP------- 137
GQ Q Q +QQI + G+IQ + VQ GQ Q I + QP
Sbjct: 172 GQAQQAQSGTGQTMQVMQQI-ITNTGEIQ-----QIPVQLNAGQLQYIRLAQPVSGTQVV 225
Query: 138 ----QTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITI 193
QT T Q TQ ++ QQ +Q +GQ + YQ +QQVT+P +
Sbjct: 226 QGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQL-YQ--------IQQVTMPAGQDLAQ 276
Query: 194 P 194
P
Sbjct: 277 P 277
Score = 47.4 bits (111), Expect = 2e-05
Identities = 46/146 (31%), Positives = 61/146 (41%), Gaps = 25/146 (17%)
Query: 89 TIMQVPVS-GTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQ------------QIIIQ 135
T+ Q P + QG QQ Q IQ GQ + Q QQGQT QI+
Sbjct: 109 TLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQA 168
Query: 136 QPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPA 195
QPQ Q+ T Q + V Q + T E Q I PV + LQ + + A
Sbjct: 169 QPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQI---PVQLNAGQLQYIRL---------A 216
Query: 196 ASLAGAQIVQTGANTNTTSSGQGTVT 221
++G Q+VQ T T++ Q T T
Sbjct: 217 QPVSGTQVVQGQIQTLATNAQQITQT 242
>gi|11496978 nuclear transcription factor Y, gamma isoform 2 [Homo
sapiens]
Length = 335
Score = 56.2 bits (134), Expect = 4e-08
Identities = 55/181 (30%), Positives = 78/181 (43%), Gaps = 27/181 (14%)
Query: 26 QQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPI-MVQAVPG 84
QQ VQ Q + Q ++S +Q Q++ QP Q + + GQ + +VQA P
Sbjct: 150 QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
Query: 85 GQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQP------- 137
GQ Q Q +QQI + G+IQ + VQ GQ Q I + QP
Sbjct: 210 GQAQQAQSGTGQTMQVMQQI-ITNTGEIQ-----QIPVQLNAGQLQYIRLAQPVSGTQVV 263
Query: 138 ----QTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITI 193
QT T Q TQ ++ QQ +Q +GQ + YQ +QQVT+P +
Sbjct: 264 QGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQL-YQ--------IQQVTMPAGQDLAQ 314
Query: 194 P 194
P
Sbjct: 315 P 315
Score = 47.4 bits (111), Expect = 2e-05
Identities = 46/146 (31%), Positives = 61/146 (41%), Gaps = 25/146 (17%)
Query: 89 TIMQVPVS-GTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQ------------QIIIQ 135
T+ Q P + QG QQ Q IQ GQ + Q QQGQT QI+
Sbjct: 147 TLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQA 206
Query: 136 QPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPA 195
QPQ Q+ T Q + V Q + T E Q I PV + LQ + + A
Sbjct: 207 QPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQI---PVQLNAGQLQYIRL---------A 254
Query: 196 ASLAGAQIVQTGANTNTTSSGQGTVT 221
++G Q+VQ T T++ Q T T
Sbjct: 255 QPVSGTQVVQGQIQTLATNAQQITQT 280
>gi|217272831 nuclear transcription factor Y, gamma isoform 1 [Homo
sapiens]
Length = 354
Score = 54.7 bits (130), Expect = 1e-07
Identities = 50/160 (31%), Positives = 72/160 (45%), Gaps = 9/160 (5%)
Query: 26 QQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPI-MVQAVPG 84
QQ VQ Q + Q ++S +Q Q++ QP Q + + GQ + +VQA P
Sbjct: 150 QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
Query: 85 GQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQP--QTAVT 142
GQ Q Q +QQI + G+I Q + VQ GQ Q I + QP T V
Sbjct: 210 GQAQQAQSGTGQTMQVMQQI-ITNTGEI-----QQIPVQLNAGQLQYIRLAQPVSGTQVV 263
Query: 143 AGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQ 182
GQ QT A QGQ+ A + + + + + T +QQ
Sbjct: 264 QGQIQTLATNAQQGQRNASQGKPRRCLKETLQITQTEVQQ 303
Score = 48.1 bits (113), Expect = 1e-05
Identities = 45/143 (31%), Positives = 60/143 (41%), Gaps = 25/143 (17%)
Query: 89 TIMQVPVS-GTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQ------------QIIIQ 135
T+ Q P + QG QQ Q IQ GQ + Q QQGQT QI+
Sbjct: 147 TLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQA 206
Query: 136 QPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPA 195
QPQ Q+ T Q + V Q + T E Q I PV + LQ + + A
Sbjct: 207 QPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQI---PVQLNAGQLQYIRL---------A 254
Query: 196 ASLAGAQIVQTGANTNTTSSGQG 218
++G Q+VQ T T++ QG
Sbjct: 255 QPVSGTQVVQGQIQTLATNAQQG 277
>gi|217272835 nuclear transcription factor Y, gamma isoform 5 [Homo
sapiens]
Length = 301
Score = 52.4 bits (124), Expect = 6e-07
Identities = 57/162 (35%), Positives = 70/162 (43%), Gaps = 35/162 (21%)
Query: 19 AGQIQQQQQGGVTAVQLQT--EAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTG-- 74
A Q+Q QQQG T T Q+ A QQ QT+QV+Q Q+IT+TG
Sbjct: 154 AVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTMQVMQ-----------QIITNTGEI 202
Query: 75 QPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQ---IQGGQAVQVQGQQGQTQ- 130
Q I VQ G + PVSGTQ +Q GQIQ Q Q + QQGQ Q
Sbjct: 203 QQIPVQLNAGQLQYIRLAQPVSGTQVVQ-------GQIQTLATNAQQITQTEVQQGQQQF 255
Query: 131 ------QIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQ 166
Q + Q Q + AGQ Q Q Q ++GQ
Sbjct: 256 SQFTDGQQLYQIQQVTMPAGQDLAQPMFI---QSANQPSDGQ 294
Score = 42.0 bits (97), Expect = 8e-04
Identities = 49/156 (31%), Positives = 62/156 (39%), Gaps = 35/156 (22%)
Query: 89 TIMQVPVS-GTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQII---------IQQPQ 138
T+ Q P + QG QQ Q IQ GQ + Q QQGQT Q++ IQQ
Sbjct: 147 TLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTMQVMQQIITNTGEIQQIP 206
Query: 139 TAVTAGQTQ----------TQ------QQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQ 182
+ AGQ Q TQ Q +A QQ+ QT Q DG L Q
Sbjct: 207 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ 266
Query: 183 VTVPVSGMITIPAA-SLAGAQIVQTGANTNTTSSGQ 217
+ +T+PA LA +Q + N S GQ
Sbjct: 267 IQ-----QVTMPAGQDLAQPMFIQ---SANQPSDGQ 294
Score = 32.0 bits (71), Expect = 0.84
Identities = 40/130 (30%), Positives = 51/130 (39%), Gaps = 27/130 (20%)
Query: 1 MEQYTANSNSSTEQIVVQ--AGQIQQ----QQQGGVTAVQLQTEAQVASASGQQVQTLQV 54
M+Q N+ +QI VQ AGQ+Q Q G VQ Q Q + + QQ+ +V
Sbjct: 192 MQQIITNTGE-IQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQI--QTLATNAQQITQTEV 248
Query: 55 VQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQI 114
QGQ Q + GQ Q I QV + Q L Q + Q
Sbjct: 249 QQGQQQFSQFTDGQ-----------------QLYQIQQVTMPAGQDLAQPMFIQSAN-QP 290
Query: 115 QGGQAVQVQG 124
GQA QV G
Sbjct: 291 SDGQAPQVTG 300
>gi|67010025 Sp4 transcription factor [Homo sapiens]
Length = 784
Score = 51.6 bits (122), Expect = 1e-06
Identities = 54/180 (30%), Positives = 72/180 (40%), Gaps = 29/180 (16%)
Query: 86 QGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQP-------- 137
Q ++ QV + G LQQIQ+ P Q IQ Q Q GQT Q I QQP
Sbjct: 389 QSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQA 448
Query: 138 ----------QTAVTAGQ-----TQTQQQIAVQGQQVAQTAEGQTIVYQPVNADG--TIL 180
T +GQ Q Q ++ QV Q + PV++ G T+
Sbjct: 449 VNPTQVLIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLA 508
Query: 181 QQVTVPVSGM-ITIPAASLAGAQIVQTGANTNTTSSG---QGTVTVTLPVAGNVVNSGGM 236
Q V V+G IT+ A LA +QT + N ++G QG VAG G+
Sbjct: 509 QIAPVAVAGAPITLNTAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGV 568
Score = 45.4 bits (106), Expect = 7e-05
Identities = 64/240 (26%), Positives = 91/240 (37%), Gaps = 35/240 (14%)
Query: 7 NSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQ-----GQPLM 61
N + +QI++ Q Q Q ++L T Q+A + Q V + QP
Sbjct: 64 NQATGQQQIIIDPSQGLVQLQNQPQQLELVT-TQLAGNAWQLVASTPPASKENNVSQPAS 122
Query: 62 VQVSGGQLITSTGQPIMVQAVPG---GQGQTIMQVPVSGT---QGLQQIQLVPPGQIQIQ 115
S + P ++ GQ Q I SG+ Q + Q+Q V QIQI
Sbjct: 123 SSSSSSSSNNGSASPTKTKSGNSSTPGQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQIN 182
Query: 116 GGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNA 175
+ +Q QGQ Q I Q +TA G +AQ QT+ Q
Sbjct: 183 PTSSSSLQDLQGQIQLISAGNNQAILTAANR------TASGNILAQNLANQTVPVQ---- 232
Query: 176 DGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGG 235
I V++P+ + T+P AQ+V T G VT+ LPV NV GG
Sbjct: 233 ---IRPGVSIPLQ-LQTLPGTQ---AQVV------TTLPINIGGVTLALPVINNVAAGGG 279
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 50.4 bits (119), Expect = 2e-06
Identities = 62/198 (31%), Positives = 82/198 (41%), Gaps = 32/198 (16%)
Query: 21 QIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQ 80
QIQQQQQ QLQ + Q QQ Q Q +Q QP + Q Q QP Q
Sbjct: 230 QIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQ-----PQPPPSQ 284
Query: 81 AVPGGQGQ-----------TIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQT 129
A+P Q Q PV+ Q QL P Q Q QA + GQ T
Sbjct: 285 ALPQQLQQMHHTQHHQPPPQPQQPPVAQN---QPSQLPPQSQTQPLVSQAQALPGQMLYT 341
Query: 130 Q--------QIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQ-TAEGQTIVYQPVNADGTIL 180
Q +++QQP Q Q QQQ AVQ Q AQ A G ++ + + G +
Sbjct: 342 QPPLKFVRAPMVVQQPP---VQPQVQ-QQQTAVQTAQAAQMVAPGVQMITEALAQGGMHI 397
Query: 181 QQVTVPVSGMITIPAASL 198
+ P + + IP++S+
Sbjct: 398 RARFPPTTAVSAIPSSSI 415
Score = 38.5 bits (88), Expect = 0.009
Identities = 50/171 (29%), Positives = 62/171 (36%), Gaps = 30/171 (17%)
Query: 14 QIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITST 73
Q+ +Q +QQQQQ Q Q + Q A QQ Q Q Q Q +Q
Sbjct: 152 QLQLQQVALQQQQQ----QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ-------- 199
Query: 74 GQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQII 133
Q V Q LQQ Q I++ Q+Q QQ Q Q+I
Sbjct: 200 -----------------FQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIA 242
Query: 134 -IQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQV 183
+Q Q Q Q QQQ A+Q Q Q Q P A LQQ+
Sbjct: 243 QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQM 293
Score = 33.5 bits (75), Expect = 0.29
Identities = 32/101 (31%), Positives = 39/101 (38%)
Query: 71 TSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQ 130
TS P + V QT +Q+ Q QQ Q Q Q Q Q QQ Q Q
Sbjct: 133 TSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQ 192
Query: 131 QIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQ 171
Q +QQ AV Q Q QQQ Q + + Q + Q
Sbjct: 193 QSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQ 233
Score = 29.3 bits (64), Expect = 5.4
Identities = 38/130 (29%), Positives = 57/130 (43%), Gaps = 9/130 (6%)
Query: 15 IVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTG 74
+VVQ +Q Q Q TAVQ AQ+ A G Q+ T + QG + + T+
Sbjct: 352 MVVQQPPVQPQVQQQQTAVQTAQAAQMV-APGVQMITEALAQGG---MHIRARFPPTTAV 407
Query: 75 QPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIII 134
I ++P G+ Q + QV S L + PGQ Q+Q Q++ Q
Sbjct: 408 SAIPSSSIPLGR-QPMAQVSQS---SLPMLSSPSPGQ-QVQTPQSMPPPPQPSPQPGQPS 462
Query: 135 QQPQTAVTAG 144
QP + V++G
Sbjct: 463 SQPNSNVSSG 472
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 47.0 bits (110), Expect = 3e-05
Identities = 79/292 (27%), Positives = 109/292 (37%), Gaps = 52/292 (17%)
Query: 21 QIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQ 80
QIQQQQQ QLQ + Q QQ Q Q +Q QP + Q Q QP Q
Sbjct: 230 QIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQ-----PQPPPSQ 284
Query: 81 AVPGGQGQ-----------TIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQT 129
A+P Q Q PV+ Q QL P Q Q QA + GQ T
Sbjct: 285 ALPQQLQQMHHTQHHQPPPQPQQPPVAQN---QPSQLPPQSQTQPLVSQAQALPGQMLYT 341
Query: 130 Q--------QIIIQQP------QTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNA 175
Q +++QQP Q TA QT Q+ G QV+Q++ P+ +
Sbjct: 342 QPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSS-------LPMLS 394
Query: 176 DGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGG 235
+ QQV P S M P S Q + N+N +S + + LP +
Sbjct: 395 SPSPGQQVQTPQS-MPPPPQPSPQPGQ-PSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSP 452
Query: 236 MVMMVPGAGSVPAIQRIPLP----------GAEMLEEEPLYVNAKQYHRILK 277
+ P SVP+ + P G+ EE+ KQ + ++
Sbjct: 453 VTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIE 504
Score = 38.5 bits (88), Expect = 0.009
Identities = 50/171 (29%), Positives = 62/171 (36%), Gaps = 30/171 (17%)
Query: 14 QIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITST 73
Q+ +Q +QQQQQ Q Q + Q A QQ Q Q Q Q +Q
Sbjct: 152 QLQLQQVALQQQQQ----QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ-------- 199
Query: 74 GQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQII 133
Q V Q LQQ Q I++ Q+Q QQ Q Q+I
Sbjct: 200 -----------------FQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIA 242
Query: 134 -IQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQV 183
+Q Q Q Q QQQ A+Q Q Q Q P A LQQ+
Sbjct: 243 QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQM 293
Score = 33.5 bits (75), Expect = 0.29
Identities = 32/101 (31%), Positives = 39/101 (38%)
Query: 71 TSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQ 130
TS P + V QT +Q+ Q QQ Q Q Q Q Q QQ Q Q
Sbjct: 133 TSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQ 192
Query: 131 QIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQ 171
Q +QQ AV Q Q QQQ Q + + Q + Q
Sbjct: 193 QSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQ 233
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 46.6 bits (109), Expect = 3e-05
Identities = 52/190 (27%), Positives = 81/190 (42%), Gaps = 28/190 (14%)
Query: 26 QQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGG 85
QQ + ++T V + QQV T Q+++GQP+ VS ++ST PG
Sbjct: 2195 QQSTLGKAIIRTPVMVQPGAPQQVMT-QIIRGQPVSTAVSAPNTVSST---------PGQ 2244
Query: 86 QGQTIMQVPVSGTQGLQQIQLVPP----GQIQIQGGQAVQV-QGQQGQTQQIIIQQPQTA 140
+ T + T +Q PP GQ+++ Q Q+ QG G ++ Q Q
Sbjct: 2245 KSLT----SATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQ-- 2298
Query: 141 VTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAG 200
GQT Q Q+ QG V GQ ++ Q +GT+ + + P++ T AS
Sbjct: 2299 ---GQTTGQLQLIPQGVTVL-PGPGQQLM-QAAMPNGTVQRFLFTPLA--TTATTASTTT 2351
Query: 201 AQIVQTGANT 210
+ T A T
Sbjct: 2352 TTVSTTAAGT 2361
Score = 43.5 bits (101), Expect = 3e-04
Identities = 62/238 (26%), Positives = 91/238 (38%), Gaps = 34/238 (14%)
Query: 3 QYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQ---- 58
Q + S +ST I A Q + QQG V Q G Q T+ V+QGQ
Sbjct: 2244 QKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTV-VIQGQGQTT 2302
Query: 59 -PLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVS------------------GTQ 99
L + G ++ GQ +M A+P G Q + P++ GT
Sbjct: 2303 GQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTG 2362
Query: 100 GLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQV 159
+Q +L P Q+Q Q + Q + QPQTA + Q Q Q Q Q
Sbjct: 2363 EQRQSKLSP----QMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2418
Query: 160 AQT---AEGQTIV--YQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNT 212
QT + QT V + P A T Q V+ + P +++ G V+ + + T
Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ-SQPQSNVQGQSPVRVQSPSQT 2475
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/151 (27%), Positives = 65/151 (43%), Gaps = 17/151 (11%)
Query: 20 GQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMV 79
G + Q Q + Q Q + Q S + +VQT VQ Q + + S QP
Sbjct: 2390 GPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQ-----TQTTVSSHVPSEAQPTHA 2444
Query: 80 QAVPGGQGQTIMQV-PVSGTQGLQQIQLVPPGQIQIQGGQAVQVQ-GQQGQTQQIIIQ-- 135
Q+ + Q Q P S QG +++ P Q +I+ Q+ GQQ Q Q Q
Sbjct: 2445 QS---SKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPI 2501
Query: 136 --QPQTAV---TAGQTQTQQQIAVQGQQVAQ 161
QP T++ + GQ Q+Q Q+ ++ V +
Sbjct: 2502 PIQPHTSLQIPSQGQPQSQPQVVMKHNAVIE 2532
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 46.6 bits (109), Expect = 3e-05
Identities = 52/190 (27%), Positives = 81/190 (42%), Gaps = 28/190 (14%)
Query: 26 QQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGG 85
QQ + ++T V + QQV T Q+++GQP+ VS ++ST PG
Sbjct: 2069 QQSTLGKAIIRTPVMVQPGAPQQVMT-QIIRGQPVSTAVSAPNTVSST---------PGQ 2118
Query: 86 QGQTIMQVPVSGTQGLQQIQLVPP----GQIQIQGGQAVQV-QGQQGQTQQIIIQQPQTA 140
+ T + T +Q PP GQ+++ Q Q+ QG G ++ Q Q
Sbjct: 2119 KSLT----SATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQ-- 2172
Query: 141 VTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAG 200
GQT Q Q+ QG V GQ ++ Q +GT+ + + P++ T AS
Sbjct: 2173 ---GQTTGQLQLIPQGVTVL-PGPGQQLM-QAAMPNGTVQRFLFTPLA--TTATTASTTT 2225
Query: 201 AQIVQTGANT 210
+ T A T
Sbjct: 2226 TTVSTTAAGT 2235
Score = 46.6 bits (109), Expect = 3e-05
Identities = 50/184 (27%), Positives = 78/184 (42%), Gaps = 20/184 (10%)
Query: 20 GQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMV 79
G + Q Q + Q Q + Q S + +VQT VQ Q + + S QP
Sbjct: 2264 GPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQ-----TQTTVSSHVPSEAQPTHA 2318
Query: 80 QAVPGGQGQTIMQV-PVSGTQGLQQIQLVPPGQIQIQGGQAVQVQ-GQQGQTQQIIIQ-- 135
Q+ + Q Q P S QG +++ P Q +I+ Q+ GQQ Q Q Q
Sbjct: 2319 QS---SKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPI 2375
Query: 136 --QPQTAV---TAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGM 190
QP T++ + GQ Q+Q Q+ Q + + GQT+ V++ Q+ P +
Sbjct: 2376 PIQPHTSLQIPSQGQPQSQPQVQSSTQTL---SSGQTLNQVTVSSPSRPQLQIQQPQPQV 2432
Query: 191 ITIP 194
I +P
Sbjct: 2433 IAVP 2436
Score = 46.2 bits (108), Expect = 4e-05
Identities = 56/184 (30%), Positives = 76/184 (41%), Gaps = 21/184 (11%)
Query: 2 EQYTANSNSSTEQIVVQAGQIQQQQQG---------GVTAVQLQTEAQVASASGQQVQTL 52
E ++ SS Q+ Q+ Q Q QG T ++ T +Q++ QVQT
Sbjct: 2312 EAQPTHAQSSKPQVAAQS-QPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQT- 2369
Query: 53 QVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGG-----QGQTIMQVPVSGTQGLQ-QIQL 106
QP+ +Q I S GQP V GQT+ QV VS Q QIQ
Sbjct: 2370 --TTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQ 2427
Query: 107 VPPGQIQI-QGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEG 165
P I + Q Q VQV Q Q+Q + Q Q + Q + Q I +Q QT +
Sbjct: 2428 PQPQVIAVPQLQQQVQVLSQI-QSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQI 2486
Query: 166 QTIV 169
Q +V
Sbjct: 2487 QNVV 2490
Score = 43.5 bits (101), Expect = 3e-04
Identities = 62/238 (26%), Positives = 91/238 (38%), Gaps = 34/238 (14%)
Query: 3 QYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQ---- 58
Q + S +ST I A Q + QQG V Q G Q T+ V+QGQ
Sbjct: 2118 QKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTV-VIQGQGQTT 2176
Query: 59 -PLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPV------------------SGTQ 99
L + G ++ GQ +M A+P G Q + P+ +GT
Sbjct: 2177 GQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTG 2236
Query: 100 GLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQV 159
+Q +L P Q+Q Q + Q + QPQTA + Q Q Q Q Q
Sbjct: 2237 EQRQSKLSP----QMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2292
Query: 160 AQT---AEGQTIV--YQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNT 212
QT + QT V + P A T Q V+ + P +++ G V+ + + T
Sbjct: 2293 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ-SQPQSNVQGQSPVRVQSPSQT 2349
Score = 39.7 bits (91), Expect = 0.004
Identities = 43/163 (26%), Positives = 70/163 (42%), Gaps = 22/163 (13%)
Query: 5 TANSNSSTEQIVVQAG-----QIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQP 59
T +S + Q+ V + QIQQ Q + QLQ + QV S Q+Q+ V Q
Sbjct: 2403 TLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLS----QIQSQVVAQ--- 2455
Query: 60 LMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQA 119
+ Q SG PI +Q Q I V +Q+ Q+Q Q
Sbjct: 2456 IQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQE---------QLQRVQQ 2506
Query: 120 VQVQGQQGQTQQIIIQQPQTAVTAGQTQ-TQQQIAVQGQQVAQ 161
++ Q Q+ + QQI I++ T + Q++ Q+Q+ ++ V +
Sbjct: 2507 LRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIE 2549
>gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens]
Length = 337
Score = 46.2 bits (108), Expect = 4e-05
Identities = 47/154 (30%), Positives = 64/154 (41%), Gaps = 29/154 (18%)
Query: 29 GVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQ 88
GVT VQ Q+ + SGQ +Q ++ G + Q ++ Q ++ Q PGG
Sbjct: 109 GVTPVQ-----QILTNSGQLLQVVRAANGAQYIFQPQQSVVLQ---QQVIPQMQPGG--- 157
Query: 89 TIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAV----TAG 144
+Q PV +QQ+ PG I Q G +Q QQI+ +T V A
Sbjct: 158 --VQAPV-----IQQVLAPLPGGISPQTGVIIQ-------PQQILFTGNKTQVIPTTVAA 203
Query: 145 QTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGT 178
T Q QI GQQ Q QT + DGT
Sbjct: 204 PTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGT 237
Score = 35.8 bits (81), Expect = 0.058
Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 18/137 (13%)
Query: 118 QAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADG 177
Q+ V G + QQ+++Q Q Q Q QQQ Q QT+ Q
Sbjct: 13 QSRAVDGFHSEEQQLLLQVQQ------QHQPQQQQHHHHHHHQQAQPQQTVPQQAQT--- 63
Query: 178 TILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTL-----PVAGNVVN 232
QQV +P S T P + ++++Q N + S+ T+ L PV + N
Sbjct: 64 ---QQVLIPASQQATAPQVIVPDSKLIQ-HMNASNMSAAATAATLALPAGVTPVQQILTN 119
Query: 233 SGGMVMMVPGAGSVPAI 249
SG ++ +V A I
Sbjct: 120 SGQLLQVVRAANGAQYI 136
>gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens]
Length = 376
Score = 46.2 bits (108), Expect = 4e-05
Identities = 47/154 (30%), Positives = 64/154 (41%), Gaps = 29/154 (18%)
Query: 29 GVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQ 88
GVT VQ Q+ + SGQ +Q ++ G + Q ++ Q ++ Q PGG
Sbjct: 148 GVTPVQ-----QILTNSGQLLQVVRAANGAQYIFQPQQSVVLQ---QQVIPQMQPGG--- 196
Query: 89 TIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAV----TAG 144
+Q PV +QQ+ PG I Q G +Q QQI+ +T V A
Sbjct: 197 --VQAPV-----IQQVLAPLPGGISPQTGVIIQ-------PQQILFTGNKTQVIPTTVAA 242
Query: 145 QTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGT 178
T Q QI GQQ Q QT + DGT
Sbjct: 243 PTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGT 276
Score = 35.8 bits (81), Expect = 0.058
Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 18/137 (13%)
Query: 118 QAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADG 177
Q+ V G + QQ+++Q Q Q Q QQQ Q QT+ Q
Sbjct: 52 QSRAVDGFHSEEQQLLLQVQQ------QHQPQQQQHHHHHHHQQAQPQQTVPQQAQT--- 102
Query: 178 TILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTL-----PVAGNVVN 232
QQV +P S T P + ++++Q N + S+ T+ L PV + N
Sbjct: 103 ---QQVLIPASQQATAPQVIVPDSKLIQ-HMNASNMSAAATAATLALPAGVTPVQQILTN 158
Query: 233 SGGMVMMVPGAGSVPAI 249
SG ++ +V A I
Sbjct: 159 SGQLLQVVRAANGAQYI 175
>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
Length = 1200
Score = 45.1 bits (105), Expect = 1e-04
Identities = 34/92 (36%), Positives = 42/92 (45%), Gaps = 3/92 (3%)
Query: 67 GQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQ 126
G L QP+ V GGQ Q+ Q +QQ Q PP Q Q G Q + +Q Q
Sbjct: 230 GHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQ 289
Query: 127 GQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQ 158
Q QQI QPQ Q Q QQ+ +Q +Q
Sbjct: 290 TQPQQIRPSQPQ---PPPQQQQPQQLQLQQRQ 318
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 44.7 bits (104), Expect = 1e-04
Identities = 53/159 (33%), Positives = 69/159 (43%), Gaps = 17/159 (10%)
Query: 13 EQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQP-LMVQVSGGQLIT 71
+Q +Q Q+Q+QQ+ QLQT QQ Q QV+Q Q L QV QL+
Sbjct: 155 QQQQLQPQQVQEQQRLQQQQEQLQT---------QQAQEQQVLQQQEQLQQQVQEQQLLQ 205
Query: 72 STGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQ----LVPPGQIQIQGGQAVQVQGQQG 127
+ + Q + Q Q Q + LQQ Q L GQ+Q Q Q Q Q QQ
Sbjct: 206 QQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQ 265
Query: 128 QTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQ 166
+Q Q Q + Q Q QQQ Q QQ+ Q + Q
Sbjct: 266 LLEQQQAQLQQQLLLQQQEQLQQQ---QQQQLLQQQQEQ 301
Score = 43.1 bits (100), Expect = 4e-04
Identities = 81/335 (24%), Positives = 124/335 (37%), Gaps = 52/335 (15%)
Query: 13 EQIVVQAGQIQQQQ-QGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLIT 71
+Q++ Q Q+QQQQ Q +Q Q + + GQ Q L Q L Q+ Q
Sbjct: 214 QQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQ-A 272
Query: 72 STGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPG--------------QIQIQGG 117
Q +++Q Q Q Q+ + LQQ QL PP + +
Sbjct: 273 QLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSE 332
Query: 118 QAVQVQGQQGQTQQIIIQQP-----QTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQP 172
Q ++ Q Q+ + QQ + +Q Q + Q +QQ+ Q QQ+ Q +
Sbjct: 333 QELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVE 392
Query: 173 VNADGTILQQVTVPVSGMI---TIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGN 229
+ A +Q PV + +PAA GA + G V P
Sbjct: 393 LGAQQQEVQLELTPVQPELQLELVPAAGGGGAAV-----------PGAPAAVVVAPPGYV 441
Query: 230 VVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEG 289
VV +MV A + PA+ IP P A R +RR+AR + G
Sbjct: 442 VVQE----LMVLPAVAAPAVVAIPGPAGSA---------ALTPARQRRRRRARDRPTICG 488
Query: 290 KIPKERRK----YLHESRHRHAMARKRGEGGRFFS 320
+ K + H++ H + GE G+ FS
Sbjct: 489 ECGKGFSRSTDLVRHQATHTGERPHRCGECGKGFS 523
Score = 40.4 bits (93), Expect = 0.002
Identities = 52/172 (30%), Positives = 71/172 (41%), Gaps = 13/172 (7%)
Query: 2 EQYTANSNSSTEQIVVQA----GQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQG 57
E+ NSS ++ V A +I ++ + G +QLQ Q QQ Q Q+ Q
Sbjct: 54 EEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQ-QQPQHEQLQQP 112
Query: 58 QPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGG 117
QP + Q GQ + Q Q Q + Q Q + P Q+Q Q
Sbjct: 113 QPHLELQQQPQ---QDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQR 169
Query: 118 ---QAVQVQGQQGQTQQIIIQQP--QTAVTAGQTQTQQQIAVQGQQVAQTAE 164
Q Q+Q QQ Q QQ++ QQ Q V Q QQQ +Q QQ+ Q E
Sbjct: 170 LQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE 221
Score = 34.7 bits (78), Expect = 0.13
Identities = 49/165 (29%), Positives = 68/165 (41%), Gaps = 29/165 (17%)
Query: 18 QAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPI 77
Q Q+QQ++ V +L+ E Q+ QQ+Q QV + Q L Q QL T Q
Sbjct: 129 QLSQLQQEKHQSVHHQELKPELQLMHQQ-QQLQPQQVQEQQRLQQQQE--QLQTQQAQE- 184
Query: 78 MVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQP 137
Q ++Q QQ QL Q Q+Q Q +Q Q Q Q QQ + Q
Sbjct: 185 ----------QQVLQ---------QQEQL----QQQVQEQQLLQQQ--QEQLQQQQLLQQ 219
Query: 138 QTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQ 182
Q + Q Q QQ+ Q QQ+ + + Q + LQQ
Sbjct: 220 QEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQ 264
>gi|19923559 EMSY protein [Homo sapiens]
Length = 1322
Score = 44.3 bits (103), Expect = 2e-04
Identities = 62/250 (24%), Positives = 100/250 (40%), Gaps = 23/250 (9%)
Query: 12 TEQIVVQAGQIQQQQQGGVTAVQ--LQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQL 69
T+Q V Q + QQQ + + ++ Q+ SG ++ T QV + L V+ L
Sbjct: 419 TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTA-TL 477
Query: 70 ITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPP--GQIQIQGGQAVQVQGQQG 127
TS+ PIMV + G T + +GTQ V P G++ G A V+ G
Sbjct: 478 PTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSG 537
Query: 128 QTQQIIIQQPQTAVTAGQTQTQQQI----AVQGQQVAQTAEGQTIVYQPVNADGTILQQV 183
II P++ T G I + + T++ IV Q GT +Q
Sbjct: 538 ---SIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQ-- 592
Query: 184 TVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGA 243
+P ++T + G + +Q T T + +T T P+ +V + G+
Sbjct: 593 GLPGKNVVT-TLLNAGGEKTIQ----TVPTGAKPAILTATRPITKMIVTQPKGI----GS 643
Query: 244 GSVPAIQRIP 253
PA + IP
Sbjct: 644 TVQPAAKIIP 653
Score = 33.1 bits (74), Expect = 0.38
Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 23/139 (16%)
Query: 41 VASASGQQVQTLQVVQGQPLMVQVSGGQLITST----GQPIMVQAVPGGQGQTIMQVPVS 96
+ S V +Q G+ +Q G+ + +T G +Q VP G I+ +
Sbjct: 570 IPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAIL----T 625
Query: 97 GTQGLQQIQLVPPGQIQIQGGQAVQ----------VQGQQGQTQQIIIQQPQT-AVTAGQ 145
T+ + ++ + P I G VQ V GQQG+TQ +I +P T T
Sbjct: 626 ATRPITKMIVTQPKGI----GSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVS 681
Query: 146 TQTQQQIAVQGQQVAQTAE 164
QT+Q + QQ ++ AE
Sbjct: 682 EQTRQLVTETLQQASRVAE 700
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 44.3 bits (103), Expect = 2e-04
Identities = 59/212 (27%), Positives = 84/212 (39%), Gaps = 24/212 (11%)
Query: 12 TEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLIT 71
T+ V+ + Q+ QQ QG + ++ +A QQ Q QG + L++
Sbjct: 3830 TQSRVLSSPQLAQQGQGLMGH-------RLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMS 3882
Query: 72 STGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQ 131
+GQP + G Q Q + Q LQQ Q Q Q Q +Q Q QQ Q Q
Sbjct: 3883 HSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQ- 3941
Query: 132 IIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTIL-------QQVT 184
QQ Q + Q Q QQQ Q QQ Q + Q + +N T+L QQV
Sbjct: 3942 ---QQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGL--LNQSRTLLSPQQQQQQQVA 3996
Query: 185 ----VPVSGMITIPAASLAGAQIVQTGANTNT 212
+P + + G ++ TG NT
Sbjct: 3997 LGPGMPAKPLQHFSSPGALGPTLLLTGKEQNT 4028
Score = 35.8 bits (81), Expect = 0.058
Identities = 46/171 (26%), Positives = 67/171 (39%), Gaps = 36/171 (21%)
Query: 16 VVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQ 75
+ Q Q QQQQQ + Q Q G VQT Q + +P G + S+ Q
Sbjct: 3730 LAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP------QGLMPPSSHQ 3783
Query: 76 PIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQ 135
++V Q + P G QG ++ P Q+ + Q G QG +Q+++
Sbjct: 3784 GLLV--------QQLSPQPPQGPQG-----MLGPAQVAVLQQQHPGALGPQGPHRQVLMT 3830
Query: 136 Q------PQTA-----------VTAGQTQTQQQIAVQGQQVAQTAEGQTIV 169
Q PQ A VTA Q Q QQQ QG + Q+++
Sbjct: 3831 QSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLM 3881
Score = 34.3 bits (77), Expect = 0.17
Identities = 61/278 (21%), Positives = 95/278 (34%), Gaps = 40/278 (14%)
Query: 13 EQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITS 72
+Q+ Q Q+QQQQQ Q Q + Q Q L Q Q V + G
Sbjct: 3946 QQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM---- 4001
Query: 73 TGQPIMVQAVPGGQGQTIM-----------QVPVSGTQGLQQIQLVP------PGQIQIQ 115
+P+ + PG G T++ V T+G Q P P + +
Sbjct: 4002 PAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATE 4061
Query: 116 GGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNA 175
G+ V+ Q+++ QPQ Q Q + + GQQ Q + T
Sbjct: 4062 PGE---VKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQ 4118
Query: 176 DGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSG---------QGTVTVTLPV 226
G+ V ++ P+ SL Q G+ T Q P
Sbjct: 4119 LGSGSSSEASSVPHLLAQPSVSLGD----QPGSMTQNLLGPQQPMLERPMQNNTGPQPPK 4174
Query: 227 AGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEP 264
G V+ SG +PG G +P + ++ +L + P
Sbjct: 4175 PGPVLQSG---QGLPGVGIMPTVGQLRAQLQGVLAKNP 4209
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 43.1 bits (100), Expect = 4e-04
Identities = 54/223 (24%), Positives = 79/223 (35%), Gaps = 24/223 (10%)
Query: 42 ASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVP------- 94
A A+ QT Q P S S P ++A Q T Q P
Sbjct: 1480 AKAAAAPFQTSQASASAPRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAPS 1539
Query: 95 -VSGTQGLQQIQLVPPGQIQ--IQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQ 151
+G L Q +LV P Q Q + G+ V++ Q I PQ+ V +T Q
Sbjct: 1540 HAAGQSALPQ-RLVLPSQAQARLPSGEVVKI------AQLASITGPQSRVAQPETPVTLQ 1592
Query: 152 IAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVP------VSGMITIPAASLAGAQIVQ 205
++ + Q QP+ G++LQ V+ P G + + S AGA
Sbjct: 1593 FQGSKFTLSHSQLRQLTAGQPLQLQGSVLQIVSAPGQPYLRAPGPVVMQTVSQAGAVHGA 1652
Query: 206 TGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPA 248
G+ +T + V G V + + PG S PA
Sbjct: 1653 LGSKPPAGGPSPAPLTPQVGVPGRVA-VNALAVGEPGTASKPA 1694
Score = 40.8 bits (94), Expect = 0.002
Identities = 72/256 (28%), Positives = 98/256 (38%), Gaps = 41/256 (16%)
Query: 2 EQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQL---------QTEAQVASASGQQVQTL 52
+Q +Q Q Q QQQQQ T Q+ Q+ AQ+ + + L
Sbjct: 2721 QQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHL 2780
Query: 53 QVVQGQPLMV--QVSGGQLITSTGQP---IMVQAVPGGQGQ----TIMQVPVSG------ 97
+Q Q L + Q Q ++ QP + VQ Q Q T + P G
Sbjct: 2781 IKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGT 2840
Query: 98 -TQGLQQIQL--VPPGQIQIQGGQAVQVQGQQGQTQQIIIQQP-----QTAVTAGQTQTQ 149
LQ +L VP Q+Q QG Q+Q Q Q Q+ + +P AV + T
Sbjct: 2841 TVANLQVARLTRVPTSQLQAQG----QMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTT 2896
Query: 150 QQIAVQGQQVA----QTAEGQTIVYQPVNADGTI-LQQVTVPVSGMITIPAASLAGAQIV 204
+ V G VA Q A GQT+V QPV+ + L+Q V I AA A
Sbjct: 2897 LPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQ 2956
Query: 205 QTGANTNTTSSGQGTV 220
+ A TT Q V
Sbjct: 2957 KITAQQITTPGAQQKV 2972
Score = 38.1 bits (87), Expect = 0.012
Identities = 51/189 (26%), Positives = 76/189 (40%), Gaps = 22/189 (11%)
Query: 15 IVVQAGQIQQQQQGGVTA--VQLQTEAQVASASGQQVQTLQ--VVQGQPLMVQVSGGQLI 70
I V GQ Q+ V A V +Q ++ + QQ + +Q QG + Q Q I
Sbjct: 2904 ISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQI 2963
Query: 71 TSTG--QPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQ 128
T+ G Q + A P + Q + P+S Q ++ G Q VQ Q Q +
Sbjct: 2964 TTPGAQQKVAYAAQPALKTQ-FLTTPISQAQ-------------KLAGAQQVQTQIQVAK 3009
Query: 129 TQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQ-TAEGQTIVYQP-VNADGTILQQVTVP 186
Q++ QQ A QQ + Q + Q TA GQ + P V A ++QQ +
Sbjct: 3010 LPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQ 3069
Query: 187 VSGMITIPA 195
+ T A
Sbjct: 3070 QQVVTTASA 3078
Score = 37.7 bits (86), Expect = 0.015
Identities = 70/297 (23%), Positives = 114/297 (38%), Gaps = 33/297 (11%)
Query: 43 SASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQP-IMVQAVPGGQGQTIMQVPVSGTQGL 101
S++ Q Q QVV+ Q + Q+ T QP + + A P Q +P+ +Q
Sbjct: 571 SSALQFAQQPQVVEAQTQL------QIPVKTQQPNVPIPAPPSSQ------LPIPPSQPA 618
Query: 102 QQIQLVP-PGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVA 160
Q VP PG++Q+Q Q + T+ + P + T V G
Sbjct: 619 QLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPG 678
Query: 161 QTAEGQTIVYQPVNADGTILQQVTVPVSGMI-TIPAASLAGAQIVQTGANTNTTSSGQGT 219
+ + V +P +A L VT G++ + P + AQ T++ S Q T
Sbjct: 679 PSPARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQNA-----TSSQDSSQDT 733
Query: 220 VTVTLPVAGNVVNSGGMVMMVPGAGS---VPAIQRIPLPGAE---MLEEEPLYVNAKQYH 273
+T + + N V+ + G S +P +Q P P + +LEE
Sbjct: 734 LTEQITLE-NQVHQRIAELRKAGLWSQRRLPKLQEAPRPKSHWDYLLEEMQWMATDFAQE 792
Query: 274 RILKRRQAR------AKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEK 324
R K A+ + E ++ +ER K +SR R A E F+S E+
Sbjct: 793 RRWKVAAAKKLVRTVVRHHEEKQLREERGKKEEQSRLRRIAASTAREIECFWSNIEQ 849
Score = 32.7 bits (73), Expect = 0.49
Identities = 34/132 (25%), Positives = 50/132 (37%), Gaps = 18/132 (13%)
Query: 51 TLQVVQGQPLMVQVSGGQLITSTGQPIMVQA---VPGGQGQTIMQVPVSGTQGLQQIQLV 107
++ QG + V+ ++T+ P+ A VP T +Q+P + +
Sbjct: 2659 SMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPG---------KTI 2709
Query: 108 PPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQT 167
P Q+ Q Q Q QQ Q QQ QQ Q Q Q QQQ Q +GQ
Sbjct: 2710 TPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQ------QQQQQQQTTTTSQVQVPQIQGQA 2763
Query: 168 IVYQPVNADGTI 179
+ A G +
Sbjct: 2764 QSPAQIKAVGKL 2775
Score = 29.6 bits (65), Expect = 4.2
Identities = 17/48 (35%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
Query: 31 TAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIM 78
T V LQ + + S Q++ Q+ GQPL +Q S Q++++ GQP +
Sbjct: 1587 TPVTLQFQGSKFTLSHSQLR--QLTAGQPLQLQGSVLQIVSAPGQPYL 1632
>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
Length = 1073
Score = 43.1 bits (100), Expect = 4e-04
Identities = 74/273 (27%), Positives = 96/273 (35%), Gaps = 49/273 (17%)
Query: 15 IVVQAGQIQQQQQ------GGVTAVQL-------------------------QTEAQVAS 43
+VVQ Q QQQQQ GVT Q+ Q + Q
Sbjct: 494 VVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQE 553
Query: 44 ASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQ 103
S QQ Q LQ V Q M +G Q P+ V V GQ ++ Q L
Sbjct: 554 LSYQQKQGLQPVPLQATMSAATGIQ-----PSPVNVVGVTSALGQQPSISSLAQPQ-LPY 607
Query: 104 IQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTA 163
Q PP Q + G Q Q Q GQ Q ++ Q TQ VQ Q + QTA
Sbjct: 608 SQAAPPVQTPLPGAPPPQ-QLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTA 666
Query: 164 EGQTIVYQPVNAD---GTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTV 220
QP +A GT + V P I +P A + A + GQ
Sbjct: 667 MSSG---QPSSAGVGAGTTVIPVAQPQG--IQLPVQPTA---VPAQPAGASVQPVGQAPA 718
Query: 221 TVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIP 253
V+ G+ + + G +P A P+ Q P
Sbjct: 719 AVSAVPTGSQIANIGQQANIPTAVQQPSTQVPP 751
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 43.1 bits (100), Expect = 4e-04
Identities = 40/135 (29%), Positives = 49/135 (36%), Gaps = 3/135 (2%)
Query: 97 GTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQG 156
G + +QQ +L P Q Q Q Q Q Q Q A Q Q Q Q Q
Sbjct: 164 GVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 223
Query: 157 QQVAQT-AEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSS 215
Q AQ A+ Q + QV G T +S A A V T +++T SS
Sbjct: 224 QAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPA--VSTSTSSSTPSS 281
Query: 216 GQGTVTVTLPVAGNV 230
T T VA V
Sbjct: 282 TTSTTTTATSVAQTV 296
Score = 33.1 bits (74), Expect = 0.38
Identities = 59/241 (24%), Positives = 80/241 (33%), Gaps = 35/241 (14%)
Query: 22 IQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQA 81
IQQ + + A Q Q +AQ + + Q Q Q Q QA
Sbjct: 168 IQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQ--------------------AQA 207
Query: 82 VPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQ---QGQTQQIIIQQPQ 138
Q Q Q Q Q Q Q Q Q QVQ Q Q Q Q + P
Sbjct: 208 QAQAQAQAQAQ-----AQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPT 262
Query: 139 TAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASL 198
T+ A T + + T T V Q V+ T Q + VS + P S+
Sbjct: 263 TSSPAPAVSTSTSSSTPSSTTSTTTTA-TSVAQTVSTPTTQDQTPSSAVS--VATPTVSV 319
Query: 199 AGAQIVQTGANTNTTSSGQ---GTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLP 255
+ T T Q V ++P + + VM+ P +P + IPLP
Sbjct: 320 STPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMP-IPLP 378
Query: 256 G 256
G
Sbjct: 379 G 379
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 43.1 bits (100), Expect = 4e-04
Identities = 40/135 (29%), Positives = 49/135 (36%), Gaps = 3/135 (2%)
Query: 97 GTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQG 156
G + +QQ +L P Q Q Q Q Q Q Q A Q Q Q Q Q
Sbjct: 164 GVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 223
Query: 157 QQVAQT-AEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSS 215
Q AQ A+ Q + QV G T +S A A V T +++T SS
Sbjct: 224 QAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPA--VSTSTSSSTPSS 281
Query: 216 GQGTVTVTLPVAGNV 230
T T VA V
Sbjct: 282 TTSTTTTATSVAQTV 296
Score = 36.2 bits (82), Expect = 0.045
Identities = 60/246 (24%), Positives = 83/246 (33%), Gaps = 35/246 (14%)
Query: 22 IQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQA 81
IQQ + + A Q Q +AQ + + Q Q Q Q QA
Sbjct: 168 IQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQ--------------------AQA 207
Query: 82 VPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQ---QGQTQQIIIQQPQ 138
Q Q Q Q Q Q Q Q Q QVQ Q Q Q Q + P
Sbjct: 208 QAQAQAQAQAQ-----AQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPT 262
Query: 139 TAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASL 198
T+ A T + + T T V Q V+ T Q + VS + P S+
Sbjct: 263 TSSPAPAVSTSTSSSTPSSTTSTTTTA-TSVAQTVSTPTTQDQTPSSAVS--VATPTVSV 319
Query: 199 AGAQIVQTGANTNTTSSGQ---GTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLP 255
+ T T Q V ++P + + VM+ P +P + IPLP
Sbjct: 320 STPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMP-IPLP 378
Query: 256 GAEMLE 261
G M++
Sbjct: 379 GVAMMQ 384
>gi|38372901 Sp1 transcription factor isoform a [Homo sapiens]
Length = 785
Score = 42.4 bits (98), Expect = 6e-04
Identities = 52/217 (23%), Positives = 78/217 (35%), Gaps = 38/217 (17%)
Query: 90 IMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQV-------------------QGQQGQTQ 130
IM SG+ G P +QG A+ + Q QQ Q Q
Sbjct: 338 IMNFTTSGSSGTNSQGQTPQRVSGLQGSDALNIQQNQTSGGSLQAGQQKEGEQNQQTQQQ 397
Query: 131 QIIIQQP-----------QTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTI 179
QI+IQ Q A +GQT T Q I+ Q+ Q + Q + N+ I
Sbjct: 398 QILIQPQLVQGGQALQALQAAPLSGQTFTTQAIS---QETLQNLQLQAV----PNSGPII 450
Query: 180 LQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMM 239
++ TV +G ++ L Q+ A T T + QG + +
Sbjct: 451 IRTPTVGPNGQVSWQTLQLQNLQVQNPQAQTITLAPMQGVSLGQTSSSNTTLTPIASAAS 510
Query: 240 VP-GAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRI 275
+P G +V A Q +PG + + L + Q H I
Sbjct: 511 IPAGTVTVNAAQLSSMPGLQTINLSALGTSGIQVHPI 547
Score = 40.4 bits (93), Expect = 0.002
Identities = 73/275 (26%), Positives = 95/275 (34%), Gaps = 51/275 (18%)
Query: 7 NSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEA---QVASASGQQVQTLQVVQGQPLMVQ 63
N NS+ Q Q+G + +TA QL A Q+ S+S T + G
Sbjct: 75 NENSNNSQGPSQSGGTGELD---LTATQLSQGANGWQIISSSSGATPTSKEQSGSSTNGS 131
Query: 64 ----------VSGGQLITSTGQPIMVQAV--------PGGQGQTIMQVPVSGTQGLQ--- 102
VSGGQ + + + Q V P Q Q I Q Q LQ
Sbjct: 132 NGSESSKNRTVSGGQYVVAAAPNLQNQQVLTGLPGVMPNIQYQVIPQFQTVDGQQLQFAA 191
Query: 103 ---QIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQV 159
Q+Q GQIQI G Q+ +G II P A Q + GQ
Sbjct: 192 TGAQVQQDGSGQIQIIPGANQQIITNRGSGGNIIAAMPNLLQQAVPLQGLANNVLSGQTQ 251
Query: 160 AQT----AEGQTIVYQPVNADGTIL-----QQVTV-----------PVSGMITIPAASLA 199
T A I PVN+ Q VT+ PV+ TI +ASL
Sbjct: 252 YVTNVPVALNGNITLLPVNSVSAATLTPSSQAVTISSSGSQESGSQPVTSGTTISSASLV 311
Query: 200 GAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSG 234
+Q + TN S T T + + N SG
Sbjct: 312 SSQASSSSFFTNANSYSTTTTTSNMGIM-NFTTSG 345
>gi|218751903 Sp1 transcription factor isoform b [Homo sapiens]
Length = 778
Score = 42.4 bits (98), Expect = 6e-04
Identities = 52/217 (23%), Positives = 78/217 (35%), Gaps = 38/217 (17%)
Query: 90 IMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQV-------------------QGQQGQTQ 130
IM SG+ G P +QG A+ + Q QQ Q Q
Sbjct: 331 IMNFTTSGSSGTNSQGQTPQRVSGLQGSDALNIQQNQTSGGSLQAGQQKEGEQNQQTQQQ 390
Query: 131 QIIIQQP-----------QTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTI 179
QI+IQ Q A +GQT T Q I+ Q+ Q + Q + N+ I
Sbjct: 391 QILIQPQLVQGGQALQALQAAPLSGQTFTTQAIS---QETLQNLQLQAV----PNSGPII 443
Query: 180 LQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMM 239
++ TV +G ++ L Q+ A T T + QG + +
Sbjct: 444 IRTPTVGPNGQVSWQTLQLQNLQVQNPQAQTITLAPMQGVSLGQTSSSNTTLTPIASAAS 503
Query: 240 VP-GAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRI 275
+P G +V A Q +PG + + L + Q H I
Sbjct: 504 IPAGTVTVNAAQLSSMPGLQTINLSALGTSGIQVHPI 540
Score = 40.4 bits (93), Expect = 0.002
Identities = 73/275 (26%), Positives = 95/275 (34%), Gaps = 51/275 (18%)
Query: 7 NSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEA---QVASASGQQVQTLQVVQGQPLMVQ 63
N NS+ Q Q+G + +TA QL A Q+ S+S T + G
Sbjct: 68 NENSNNSQGPSQSGGTGELD---LTATQLSQGANGWQIISSSSGATPTSKEQSGSSTNGS 124
Query: 64 ----------VSGGQLITSTGQPIMVQAV--------PGGQGQTIMQVPVSGTQGLQ--- 102
VSGGQ + + + Q V P Q Q I Q Q LQ
Sbjct: 125 NGSESSKNRTVSGGQYVVAAAPNLQNQQVLTGLPGVMPNIQYQVIPQFQTVDGQQLQFAA 184
Query: 103 ---QIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQV 159
Q+Q GQIQI G Q+ +G II P A Q + GQ
Sbjct: 185 TGAQVQQDGSGQIQIIPGANQQIITNRGSGGNIIAAMPNLLQQAVPLQGLANNVLSGQTQ 244
Query: 160 AQT----AEGQTIVYQPVNADGTIL-----QQVTV-----------PVSGMITIPAASLA 199
T A I PVN+ Q VT+ PV+ TI +ASL
Sbjct: 245 YVTNVPVALNGNITLLPVNSVSAATLTPSSQAVTISSSGSQESGSQPVTSGTTISSASLV 304
Query: 200 GAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSG 234
+Q + TN S T T + + N SG
Sbjct: 305 SSQASSSSFFTNANSYSTTTTTSNMGIM-NFTTSG 338
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 42.4 bits (98), Expect = 6e-04
Identities = 37/151 (24%), Positives = 73/151 (48%), Gaps = 7/151 (4%)
Query: 18 QAGQIQ--QQQQGGVTAV-QLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTG 74
Q GQ++ +QQ+G + + Q + + ++ Q++ L+ +GQP ++ GQL
Sbjct: 279 QMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEE 338
Query: 75 QPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIII 134
Q ++ + +GQ G GL + Q++ Q++ Q GQ ++ ++GQ + ++
Sbjct: 339 QEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQ 398
Query: 135 QQPQTAVTAGQ----TQTQQQIAVQGQQVAQ 161
Q+ Q Q Q ++Q+ QQV Q
Sbjct: 399 QEGQLKHLVQQEGQLEQQERQVEHLEQQVGQ 429
Score = 30.4 bits (67), Expect = 2.4
Identities = 40/154 (25%), Positives = 65/154 (42%), Gaps = 13/154 (8%)
Query: 18 QAGQIQQ-QQQGGVTAVQLQTEAQVASASGQ--QVQTLQVVQGQPLMVQVSGGQLITSTG 74
Q GQ++ +QQ G Q E Q+ Q Q++ L+ +GQ ++ GQL
Sbjct: 309 QMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQ 368
Query: 75 QPIMVQAVPGGQGQTIMQVPVSG-------TQGLQQIQLVPPGQIQIQGGQAVQVQGQQG 127
Q + ++ + QGQ G +G + + GQ++ Q Q ++ Q G
Sbjct: 369 QVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVG 428
Query: 128 QTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQ 161
Q + + Q+ Q Q Q Q+ V QQV Q
Sbjct: 429 QLKHLEEQEGQ---LKHLEQQQGQLEVPEQQVGQ 459
>gi|125625357 Sp2 transcription factor [Homo sapiens]
Length = 613
Score = 42.4 bits (98), Expect = 6e-04
Identities = 49/193 (25%), Positives = 70/193 (36%), Gaps = 56/193 (29%)
Query: 41 VASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQG 100
+ S+ G +Q +QG L GGQL+ + P M+ GT+
Sbjct: 86 ILSSKGNILQ----IQGSQLSASYPGGQLVFAIQNPTMIN---------------KGTRS 126
Query: 101 LQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVA 160
IQ QIQ Q +QVQ QII Q +T +
Sbjct: 127 NANIQYQAVPQIQASNSQTIQVQPNLTNQIQIIPGTNQAIITPSPSS------------- 173
Query: 161 QTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTV 220
++PV ++ + S T P VQ+GAN + G G V
Sbjct: 174 ---------HKPVP-----IKPAPIQKSSTTTTP---------VQSGANVVKLTGGGGNV 210
Query: 221 TVTLPVAGNVVNS 233
T+TLPV N+VN+
Sbjct: 211 TLTLPV-NNLVNA 222
Score = 29.6 bits (65), Expect = 4.2
Identities = 48/221 (21%), Positives = 75/221 (33%), Gaps = 21/221 (9%)
Query: 10 SSTEQIVVQAGQIQQQQQGG---VTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSG 66
SST VQ+G + GG VT AS +G Q L PL
Sbjct: 187 SSTTTTPVQSGANVVKLTGGGGNVTLTLPVNNLVNASDTGAPTQLLTESPPTPL------ 240
Query: 67 GQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQ 126
+ T + +++P Q PV+ + ++ + + IQ G + +
Sbjct: 241 ----SKTNKKARKKSLPASQP------PVAVAEQVETVLIETTADNIIQAGNNLLIVQSP 290
Query: 127 GQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVP 186
G Q ++QQ Q + Q QI Q +V Q A T+ P Q P
Sbjct: 291 GGGQPAVVQQVQVVPPKAEQQQVVQIPQQALRVVQAASA-TLPTVPQKPSQNFQIQAAEP 349
Query: 187 VSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVA 227
+ I S Q V + T++ T + P +
Sbjct: 350 TPTQVYIRTPS-GEVQTVLVQDSPPATAAATSNTTCSSPAS 389
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 41.2 bits (95), Expect = 0.001
Identities = 68/251 (27%), Positives = 101/251 (40%), Gaps = 24/251 (9%)
Query: 13 EQIVVQAGQ--IQQQQQGGVTAVQ-------LQTEAQVASASGQQV---QTLQVVQGQPL 60
+Q +QA + + QQQ G+ + + LQ VA + Q + Q Q++Q Q L
Sbjct: 54 QQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVL 113
Query: 61 MVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAV 120
Q Q + Q +M+Q + Q + QQ Q Q Q Q Q
Sbjct: 114 SPQQL--QALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 171
Query: 121 QVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTIL 180
Q Q QQ Q QQ QQ Q Q + QQQ Q QQ+A Q +V+Q L
Sbjct: 172 QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLA----AQQLVFQQQLLQMQQL 227
Query: 181 QQ----VTVPVSGMITIP--AASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSG 234
QQ +++ G+I+IP A+L + Q G + VT + N + G
Sbjct: 228 QQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHG 287
Query: 235 GMVMMVPGAGS 245
G+ + + S
Sbjct: 288 GLDLTTNNSSS 298
>gi|62865633 Sp3 transcription factor isoform 2 [Homo sapiens]
Length = 713
Score = 40.4 bits (93), Expect = 0.002
Identities = 64/248 (25%), Positives = 92/248 (37%), Gaps = 59/248 (23%)
Query: 10 SSTEQIVVQAGQIQQQQ-----------QGGVTAVQLQTEAQVASASGQQVQ-------- 50
+S+ Q V+ +Q QQ G V++VQ Q Q+ SA GQQVQ
Sbjct: 66 TSSGQYVLPLQNLQNQQIFSVAPGSDSSNGTVSSVQYQVIPQIQSADGQQVQIGFTGSSD 125
Query: 51 ---------TLQVVQGQPLMVQVSG------GQLITSTGQPIMVQAVP------GGQGQT 89
+Q++ G + SG LI TGQ + VQ V GQ Q
Sbjct: 126 NGGINQESSQIQIIPGSNQTLLASGTPSANIQNLIPQTGQ-VQVQGVAIGGSSFPGQTQV 184
Query: 90 IMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQ 149
+ VP+ G G I VP + + ++ + G QT I + GQ
Sbjct: 185 VANVPL-GLPG--NITFVPINSVDL---DSLGLSG-SSQTMTAGINADGHLINTGQAMD- 236
Query: 150 QQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGAN 209
+T E + N D + VP S +P ++ I+Q N
Sbjct: 237 -----SSDNSERTGERVSPDINETNTDTDLF----VPTSSSSQLP-VTIDSTGILQQNTN 286
Query: 210 TNTTSSGQ 217
+ TTSSGQ
Sbjct: 287 SLTTSSGQ 294
Score = 39.7 bits (91), Expect = 0.004
Identities = 60/226 (26%), Positives = 90/226 (39%), Gaps = 24/226 (10%)
Query: 30 VTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQT 89
+ T+ V ++S Q L V ++Q + L TS+GQ QG
Sbjct: 252 INETNTDTDLFVPTSSSSQ---LPVTIDSTGILQQNTNSLTTSSGQVHSSDL----QGNY 304
Query: 90 IMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQ 149
I Q PVS Q IQ+ + Q +Q+Q Q T Q I Q T QT
Sbjct: 305 I-QSPVSEETQAQNIQVSTAQPVV----QHLQLQESQQPTSQAQIVQGITP------QTI 353
Query: 150 QQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGAN 209
+ GQ ++Q A Q + Q +N ++Q TV SG +T + G Q +Q
Sbjct: 354 HGVQASGQNISQQAL-QNLQLQ-LNPGTFLIQAQTVTPSGQVTWQTFQVQGVQNLQ-NLQ 410
Query: 210 TNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVP---GAGSVPAIQRI 252
T++ Q T+T + V +GG P G +P +Q +
Sbjct: 411 IQNTAAQQITLTPVQTLTLGQVAAGGAFTSTPVSLSTGQLPNLQTV 456
Score = 35.8 bits (81), Expect = 0.058
Identities = 51/186 (27%), Positives = 75/186 (40%), Gaps = 42/186 (22%)
Query: 2 EQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLM 61
E N ST Q VVQ Q+Q+ QQ ++AQ+ Q T Q + G
Sbjct: 312 ETQAQNIQVSTAQPVVQHLQLQESQQP-------TSQAQIV-----QGITPQTIHG---- 355
Query: 62 VQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQI-----QIQG 116
VQ SG + Q + +Q P GT +Q + P GQ+ Q+QG
Sbjct: 356 VQASGQNISQQALQNLQLQLNP-------------GTFLIQAQTVTPSGQVTWQTFQVQG 402
Query: 117 GQAVQ-VQGQQGQTQQIIIQQPQT----AVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQ 171
Q +Q +Q Q QQI + QT V AG T +++ Q+ QT+
Sbjct: 403 VQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGAFTSTPVSLSTGQLPNL---QTVTVN 459
Query: 172 PVNADG 177
+++ G
Sbjct: 460 SIDSAG 465
>gi|38373693 Sp3 transcription factor isoform 1 [Homo sapiens]
Length = 781
Score = 40.4 bits (93), Expect = 0.002
Identities = 64/248 (25%), Positives = 92/248 (37%), Gaps = 59/248 (23%)
Query: 10 SSTEQIVVQAGQIQQQQ-----------QGGVTAVQLQTEAQVASASGQQVQ-------- 50
+S+ Q V+ +Q QQ G V++VQ Q Q+ SA GQQVQ
Sbjct: 134 TSSGQYVLPLQNLQNQQIFSVAPGSDSSNGTVSSVQYQVIPQIQSADGQQVQIGFTGSSD 193
Query: 51 ---------TLQVVQGQPLMVQVSG------GQLITSTGQPIMVQAVP------GGQGQT 89
+Q++ G + SG LI TGQ + VQ V GQ Q
Sbjct: 194 NGGINQESSQIQIIPGSNQTLLASGTPSANIQNLIPQTGQ-VQVQGVAIGGSSFPGQTQV 252
Query: 90 IMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQ 149
+ VP+ G G I VP + + ++ + G QT I + GQ
Sbjct: 253 VANVPL-GLPG--NITFVPINSVDL---DSLGLSG-SSQTMTAGINADGHLINTGQAMD- 304
Query: 150 QQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGAN 209
+T E + N D + VP S +P ++ I+Q N
Sbjct: 305 -----SSDNSERTGERVSPDINETNTDTDLF----VPTSSSSQLP-VTIDSTGILQQNTN 354
Query: 210 TNTTSSGQ 217
+ TTSSGQ
Sbjct: 355 SLTTSSGQ 362
Score = 39.7 bits (91), Expect = 0.004
Identities = 60/226 (26%), Positives = 90/226 (39%), Gaps = 24/226 (10%)
Query: 30 VTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQT 89
+ T+ V ++S Q L V ++Q + L TS+GQ QG
Sbjct: 320 INETNTDTDLFVPTSSSSQ---LPVTIDSTGILQQNTNSLTTSSGQVHSSDL----QGNY 372
Query: 90 IMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQ 149
I Q PVS Q IQ+ + Q +Q+Q Q T Q I Q T QT
Sbjct: 373 I-QSPVSEETQAQNIQVSTAQPVV----QHLQLQESQQPTSQAQIVQGITP------QTI 421
Query: 150 QQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGAN 209
+ GQ ++Q A Q + Q +N ++Q TV SG +T + G Q +Q
Sbjct: 422 HGVQASGQNISQQAL-QNLQLQ-LNPGTFLIQAQTVTPSGQVTWQTFQVQGVQNLQ-NLQ 478
Query: 210 TNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVP---GAGSVPAIQRI 252
T++ Q T+T + V +GG P G +P +Q +
Sbjct: 479 IQNTAAQQITLTPVQTLTLGQVAAGGAFTSTPVSLSTGQLPNLQTV 524
Score = 35.8 bits (81), Expect = 0.058
Identities = 51/186 (27%), Positives = 75/186 (40%), Gaps = 42/186 (22%)
Query: 2 EQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLM 61
E N ST Q VVQ Q+Q+ QQ ++AQ+ Q T Q + G
Sbjct: 380 ETQAQNIQVSTAQPVVQHLQLQESQQP-------TSQAQIV-----QGITPQTIHG---- 423
Query: 62 VQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQI-----QIQG 116
VQ SG + Q + +Q P GT +Q + P GQ+ Q+QG
Sbjct: 424 VQASGQNISQQALQNLQLQLNP-------------GTFLIQAQTVTPSGQVTWQTFQVQG 470
Query: 117 GQAVQ-VQGQQGQTQQIIIQQPQT----AVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQ 171
Q +Q +Q Q QQI + QT V AG T +++ Q+ QT+
Sbjct: 471 VQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGAFTSTPVSLSTGQLPNL---QTVTVN 527
Query: 172 PVNADG 177
+++ G
Sbjct: 528 SIDSAG 533
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 40.0 bits (92), Expect = 0.003
Identities = 58/220 (26%), Positives = 86/220 (39%), Gaps = 17/220 (7%)
Query: 32 AVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIM 91
+V + T + QQ+ QV+ Q L + Q + Q + + Q Q +
Sbjct: 115 SVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ-EFYKKQQEQLHL 173
Query: 92 QVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQ 151
Q+ Q QQ Q Q Q Q Q Q QQ Q QQ QQ Q Q + QQQ
Sbjct: 174 QLLQQQQQQQQQQQQ------QQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ 227
Query: 152 IAVQGQQVAQTAEGQTIVYQPVNADGTILQQ----VTVPVSGMITIP--AASLAGAQIVQ 205
Q QQ+A Q +V+Q LQQ +++ G+I+IP A+L + Q
Sbjct: 228 QQQQQQQLA----AQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQ 283
Query: 206 TGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGS 245
G + VT + N + GG+ + + S
Sbjct: 284 AGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSS 323
Score = 35.0 bits (79), Expect = 0.099
Identities = 50/181 (27%), Positives = 74/181 (40%), Gaps = 16/181 (8%)
Query: 30 VTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQT 89
+T Q+Q Q S QQ+Q L Q ++ Q + + + +Q + Q Q
Sbjct: 124 ITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ 183
Query: 90 IMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQ-GQQGQTQQIIIQQPQTAVTAGQTQT 148
Q Q QQ Q Q Q Q Q Q G+Q + QQ QQ Q + A Q
Sbjct: 184 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ-QQQQQQLAAQQLVF 242
Query: 149 QQQI----AVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIV 204
QQQ+ +Q QQ + + Q ++ P Q +PV ++P A L+ A+I
Sbjct: 243 QQQLLQMQQLQQQQHLLSLQRQGLISIPPG-------QAALPVQ---SLPQAGLSPAEIQ 292
Query: 205 Q 205
Q
Sbjct: 293 Q 293
Score = 29.3 bits (64), Expect = 5.4
Identities = 55/203 (27%), Positives = 72/203 (35%), Gaps = 13/203 (6%)
Query: 13 EQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITS 72
EQ+ +Q Q QQQQQ Q Q + Q QQ Q Q Q Q Q G+
Sbjct: 169 EQLHLQLLQQQQQQQ----QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKE 224
Query: 73 TGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQ----IQLVPPGQIQIQGGQ-AVQVQG-QQ 126
Q Q Q Q + Q + Q LQQ + L G I I GQ A+ VQ Q
Sbjct: 225 QQQQQQQQQQLAAQ-QLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQ 283
Query: 127 GQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVP 186
IQQ VT + I G + T A I
Sbjct: 284 AGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSI-- 341
Query: 187 VSGMITIPAASLAGAQIVQTGAN 209
V+G ++ +A + +TGA+
Sbjct: 342 VNGQSSVLSARRDSSSHEETGAS 364
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,571,622
Number of Sequences: 37866
Number of extensions: 601892
Number of successful extensions: 2592
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 152
Number of HSP's that attempted gapping in prelim test: 1937
Number of HSP's gapped (non-prelim): 545
length of query: 347
length of database: 18,247,518
effective HSP length: 103
effective length of query: 244
effective length of database: 14,347,320
effective search space: 3500746080
effective search space used: 3500746080
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.