BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] (1051 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 2140 0.0 gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 2083 0.0 gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 650 0.0 gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 632 0.0 gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 628 e-179 gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 619 e-177 gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 522 e-148 gi|49170034 integrin, alpha 8 [Homo sapiens] 289 8e-78 gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 275 1e-73 gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 270 5e-72 gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 269 1e-71 gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 260 4e-69 gi|56237029 integrin alpha 5 precursor [Homo sapiens] 258 2e-68 gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 248 2e-65 gi|67191027 integrin alpha 4 precursor [Homo sapiens] 245 2e-64 gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 233 9e-61 gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 179 2e-44 gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 176 1e-43 gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 173 7e-43 gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 172 2e-42 gi|116295258 integrin alpha 2 precursor [Homo sapiens] 171 3e-42 gi|148728188 integrin, alpha E precursor [Homo sapiens] 170 6e-42 gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 167 6e-41 gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 164 5e-40 gi|62548866 integrin, alpha D precursor [Homo sapiens] 156 8e-38 gi|34452173 integrin alpha X precursor [Homo sapiens] 147 7e-35 gi|29171717 glycosylphosphatidylinositol specific phospholipase ... 63 1e-09 gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 35 0.37 gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 35 0.37 gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 35 0.48 >gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] Length = 1051 Score = 2140 bits (5545), Expect = 0.0 Identities = 1051/1051 (100%), Positives = 1051/1051 (100%) Query: 1 MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR 60 MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR Sbjct: 1 MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR 60 Query: 61 QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIE 120 QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIE Sbjct: 61 QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIE 120 Query: 121 DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTY 180 DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTY Sbjct: 121 DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTY 180 Query: 181 HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK 240 HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK Sbjct: 181 HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK 240 Query: 241 DPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEG 300 DPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEG Sbjct: 241 DPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEG 300 Query: 301 SQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLL 360 SQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLL Sbjct: 301 SQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLL 360 Query: 361 LHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGE 420 LHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGE Sbjct: 361 LHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGE 420 Query: 421 KLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVL 480 KLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVL Sbjct: 421 KLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVL 480 Query: 481 DPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFH 540 DPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFH Sbjct: 481 DPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFH 540 Query: 541 GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA 600 GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA Sbjct: 541 GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA 600 Query: 601 QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT 660 QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT Sbjct: 601 QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT 660 Query: 661 RTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAF 720 RTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAF Sbjct: 661 RTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAF 720 Query: 721 EVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM 780 EVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM Sbjct: 721 EVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM 780 Query: 781 GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG 840 GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG Sbjct: 781 GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG 840 Query: 841 NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSET 900 NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSET Sbjct: 841 NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSET 900 Query: 901 VLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRT 960 VLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRT Sbjct: 901 VLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRT 960 Query: 961 SIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFK 1020 SIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFK Sbjct: 961 SIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFK 1020 Query: 1021 RARTRALYEAKRQKAEMKSQPSETERLTDDY 1051 RARTRALYEAKRQKAEMKSQPSETERLTDDY Sbjct: 1021 RARTRALYEAKRQKAEMKSQPSETERLTDDY 1051 >gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] Length = 1066 Score = 2083 bits (5397), Expect = 0.0 Identities = 1026/1044 (98%), Positives = 1029/1044 (98%), Gaps = 3/1044 (0%) Query: 1 MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR 60 MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR Sbjct: 1 MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR 60 Query: 61 QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIE 120 QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIE Sbjct: 61 QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIE 120 Query: 121 DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTY 180 DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTY Sbjct: 121 DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTY 180 Query: 181 HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK 240 HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK Sbjct: 181 HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK 240 Query: 241 DPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEG 300 DPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEG Sbjct: 241 DPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEG 300 Query: 301 SQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLL 360 SQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLL Sbjct: 301 SQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLL 360 Query: 361 LHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGE 420 LHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGE Sbjct: 361 LHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGE 420 Query: 421 KLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVL 480 KLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVL Sbjct: 421 KLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVL 480 Query: 481 DPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFH 540 DPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFH Sbjct: 481 DPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFH 540 Query: 541 GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA 600 GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA Sbjct: 541 GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA 600 Query: 601 QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT 660 QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT Sbjct: 601 QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT 660 Query: 661 RTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAF 720 RTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAF Sbjct: 661 RTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAF 720 Query: 721 EVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM 780 EVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM Sbjct: 721 EVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM 780 Query: 781 GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG 840 GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG Sbjct: 781 GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG 840 Query: 841 NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSET 900 NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSET Sbjct: 841 NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSET 900 Query: 901 VLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRT 960 VLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRT Sbjct: 901 VLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRT 960 Query: 961 SIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFK 1020 SIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKC FFK Sbjct: 961 SIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCDFFK 1020 Query: 1021 RARTRAL---YEAKRQKAEMKSQP 1041 R R + Y A R + E + P Sbjct: 1021 RTRYYQIMPKYHAVRIREEERYPP 1044 >gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo sapiens] Length = 1073 Score = 650 bits (1677), Expect = 0.0 Identities = 416/1094 (38%), Positives = 600/1094 (54%), Gaps = 87/1094 (7%) Query: 16 LCALALMVAAGGCVVSAFNLDTRF-LVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGA 74 LC L L + +AFNLDTR V+++ G+PGSLFG+S+A+H Q + + + LLL GA Sbjct: 7 LCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGA 66 Query: 75 PRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPA 134 PR A+P NRTG +Y C +TA + C R+ DP ED W+GVTV SQGP Sbjct: 67 PRAEALPLQRANRTGGLYSCDITA-RGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPG 125 Query: 135 GRVLVCAHRYTQVLWSGSEDQRRMV-GKCYVRGNDLELDSSDDWQTYHNEMCNSNT-DYL 192 G+V+ CAHRY + ++ + R + G+CYV +L ++ DD C+ + Sbjct: 126 GKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIE--DDMDGGDWSFCDGRLRGHE 183 Query: 193 ETGMCQLGTSGGFTQNTVY--FGAPGAYNWKGNSYMIQRKEWDLSEYSYKD-PEDQG--- 246 + G CQ G + FT++ Y FGAPG YNWKG + Q+ ++D P + G Sbjct: 184 KFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGET 243 Query: 247 -----------NLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEA-GGDLRR 294 N Y+G+++ G I+ IT V+GAPR H GAV LL ++ L Sbjct: 244 EHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLP 303 Query: 295 RQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFP 354 + +G + + FG +A+ DLN DGWQD+++GAP YF+R EVGGA+YV+MNQ G Sbjct: 304 EHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNN 363 Query: 355 AHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQ 414 P + L+G S FG++V +IGDINQDG+ DIAVGAP++ LGKV+IYH S+ G+ +P Sbjct: 364 VKP-IRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPT 422 Query: 415 QVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV 474 QV+ G FGYS++G MD+D N YPD+ VGSLSD + + R+RPVINI KT+ Sbjct: 423 QVLKGIS------PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINI-QKTIT 475 Query: 475 PRPAVLD---PALCTATS--CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRL 529 P +D C A S C+QV+ CF Y +A Y +I++ TLEA+++RR L Sbjct: 476 VTPNRIDLRQKTACGAPSGICLQVKSCFEY--TANPAGYNPSISIVGTLEAEKERRKSGL 533 Query: 530 ------RFAGSESAVFHGFFSMPEMR--CQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581 R GSE + + C + L L DN+RDKLRPI I+ S+ ++ P Sbjct: 534 SSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITA--SVEIQEP 591 Query: 582 DRPRLGLRSLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQMRAAFVSEQ--QQK 638 R + PILN + H +V F KE CG DN C SNL++ F + + Q K Sbjct: 592 SSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDK 651 Query: 639 LSRLQYSRDVRKLLLS--------INVTNTRTSERS----GEDAHEALLTLVVPPALLLS 686 S L + V +L+L I VTN+ ++ R+ G+DAHEA L P L S Sbjct: 652 FSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYS 711 Query: 687 SVRPPGA-------CQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQL 736 + R A C AN+ CELGNPFKRN + + VT T DL + L Sbjct: 712 AYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINL 771 Query: 737 QLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLK 796 +L T+S+QDNL P+ V L S+S V Q +FGGTV+GE MK+ ++VGS ++ Sbjct: 772 KLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIE 831 Query: 797 YEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPL 856 YEF+V +G+ L LGT L ++WP E+SNGKWLLY ++ G C P + IN L Sbjct: 832 YEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKE-INSL 890 Query: 857 NLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLEC 916 NLT S R++R++ +L A +K ++ L C+ +CV + C Sbjct: 891 NLT-------ESHNSRKKREITEKQIDDNRKFSLFAERKYQT---LNCSV-NVNCVNIRC 939 Query: 917 PIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSV 976 P+ ++ +++R+WNSTF+E+Y + + + A + + + I + N T V Sbjct: 940 PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRV 999 Query: 977 DIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQKAE 1036 + + + W++LVA+ AG+L+L L++ +LWKCGFFKR + + Y+A KAE Sbjct: 1000 TVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNK-KDHYDATYHKAE 1058 Query: 1037 MKSQPSETERLTDD 1050 + +QPS+ ERLT D Sbjct: 1059 IHAQPSDKERLTSD 1072 >gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo sapiens] Length = 1091 Score = 632 bits (1631), Expect = 0.0 Identities = 404/1067 (37%), Positives = 583/1067 (54%), Gaps = 86/1067 (8%) Query: 16 LCALALMVAAGGCVVSAFNLDTRF-LVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGA 74 LC L L + +AFNLDTR V+++ G+PGSLFG+S+A+H Q + + + LLL GA Sbjct: 7 LCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGA 66 Query: 75 PRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPA 134 PR A+P NRTG +Y C +TA + C R+ DP ED W+GVTV SQGP Sbjct: 67 PRAEALPLQRANRTGGLYSCDITA-RGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPG 125 Query: 135 GRVLVCAHRYTQVLWSGSEDQRRMV-GKCYVRGNDLELDSSDDWQTYHNEMCNSNT-DYL 192 G+V+ CAHRY + ++ + R + G+CYV +L ++ DD C+ + Sbjct: 126 GKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIE--DDMDGGDWSFCDGRLRGHE 183 Query: 193 ETGMCQLGTSGGFTQNTVY--FGAPGAYNWKGNSYMIQRKEWDLSEYSYKD-PEDQG--- 246 + G CQ G + FT++ Y FGAPG YNWKG + Q+ ++D P + G Sbjct: 184 KFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGET 243 Query: 247 -----------NLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEA-GGDLRR 294 N Y+G+++ G I+ IT V+GAPR H GAV LL ++ L Sbjct: 244 EHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLP 303 Query: 295 RQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFP 354 + +G + + FG +A+ DLN DGWQD+++GAP YF+R EVGGA+YV+MNQ G Sbjct: 304 EHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNN 363 Query: 355 AHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQ 414 P + L+G S FG++V +IGDINQDG+ DIAVGAP++ LGKV+IYH S+ G+ +P Sbjct: 364 VKP-IRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPT 422 Query: 415 QVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV 474 QV+ G FGYS++G MD+D N YPD+ VGSLSD + + R+RPVINI KT+ Sbjct: 423 QVLKGIS------PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINI-QKTIT 475 Query: 475 PRPAVLD---PALCTATS--CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRL 529 P +D C A S C+QV+ CF Y +A Y +I++ TLEA+++RR L Sbjct: 476 VTPNRIDLRQKTACGAPSGICLQVKSCFEY--TANPAGYNPSISIVGTLEAEKERRKSGL 533 Query: 530 ------RFAGSESAVFHGFFSMPEMR--CQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581 R GSE + + C + L L DN+RDKLRPI I+ S+ ++ P Sbjct: 534 SSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITA--SVEIQEP 591 Query: 582 DRPRLGLRSLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQMRAAFVSEQ--QQK 638 R + PILN + H +V F KE CG DN C SNL++ F + + Q K Sbjct: 592 SSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDK 651 Query: 639 LSRLQYSRDVRKLLLS--------INVTNTRTSERS----GEDAHEALLTLVVPPALLLS 686 S L + V +L+L I VTN+ ++ R+ G+DAHEA L P L S Sbjct: 652 FSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYS 711 Query: 687 SVRPPGA-------CQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQL 736 + R A C AN+ CELGNPFKRN + + VT T DL + L Sbjct: 712 AYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINL 771 Query: 737 QLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLK 796 +L T+S+QDNL P+ V L S+S V Q +FGGTV+GE MK+ ++VGS ++ Sbjct: 772 KLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIE 831 Query: 797 YEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPL 856 YEF+V +G+ L LGT L ++WP E+SNGKWLLY ++ G C P + IN L Sbjct: 832 YEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKE-INSL 890 Query: 857 NLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLEC 916 NLT S R++R++ +L A +K ++ L C+ +CV + C Sbjct: 891 NLT-------ESHNSRKKREITEKQIDDNRKFSLFAERKYQT---LNCSV-NVNCVNIRC 939 Query: 917 PIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSV 976 P+ ++ +++R+WNSTF+E+Y + + + A + + + I + N T V Sbjct: 940 PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRV 999 Query: 977 DIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023 + + + W++LVA+ AG+L+L L++ +LWKCGFFKR+R Sbjct: 1000 TVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRSR 1046 >gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] Length = 1137 Score = 628 bits (1619), Expect = e-179 Identities = 403/1068 (37%), Positives = 595/1068 (55%), Gaps = 107/1068 (10%) Query: 32 AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91 AFNLD + KE G PGSLFG+SVALHRQ + + + LL GAP+ LA+P NRTG + Sbjct: 33 AFNLDVMGALRKE-GEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGL 91 Query: 92 YLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPAGRVLVCAHRY------T 145 + CPL+ + DC R++I D E+ WLGV+V SQGP G+++ CAHRY Sbjct: 92 FACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVD 151 Query: 146 QVLWSGSEDQRRMVGKCYVRGNDL----ELDSSDDWQTYHNEMCNSNTD-YLETGMCQLG 200 Q+L + R M+G+C+V DL ELD +W + C + + G CQ G Sbjct: 152 QIL-----ETRDMIGRCFVLSQDLAIRDELDGG-EW-----KFCEGRPQGHEQFGFCQQG 200 Query: 201 TSGGFTQNTVY--FGAPGAYNWKGNSYMIQRKEWDLSEYSYK--DPEDQ---------GN 247 T+ F+ ++ Y FGAPG YNWKG ++ D + YK DP D+ N Sbjct: 201 TAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALN 260 Query: 248 LYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYF 307 Y+G+++ G ++ + ++ V GAPR H GAV +L +++ L +L G ++ + F Sbjct: 261 SYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGF 320 Query: 308 GSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSGS 367 G ++A+ADLN+DGW DL+VGAPY+FER+EE+GGA+YV++NQ G P L L G S Sbjct: 321 GYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISP-LRLCGSPDS 379 Query: 368 AFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGL 427 FG+S+A +GD+NQDGF DIAVGAPF+G GKV+IYH SS G++ +P QV+ GE + G+ Sbjct: 380 MFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV---GI 436 Query: 428 ATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLVPRPAVLDPALCT 486 +FGYSLSG +D+D N YPDLLVGSL+D VL RARP++++ H+ ++ PR L+ C Sbjct: 437 KSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCA 496 Query: 487 A--TSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR----PPRLRFAG------- 533 + CV + +CF+Y A +Y + L Y L+AD DRR PR+ F Sbjct: 497 GGHSVCVDLRVCFSY--IAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPK 554 Query: 534 SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDA 593 +++ + C L +N++DKLR I+++++YSL R G Sbjct: 555 HQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPV 614 Query: 594 YPILNQAQALENHTEVQFQKE-CGPDNKCESNLQM-RAAFVSE-QQQKLSRLQYSRDVRK 650 PILN Q E+ F K+ CG D C+SNLQ+ RA F + + L D Sbjct: 615 APILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT 674 Query: 651 LL----------LSINVTNTRTS----ERSGEDAHEALLTLVVPPALLLSSVR-----PP 691 L L + VTN + + G+DAHEA L +++P +L S VR Sbjct: 675 ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 734 Query: 692 GACQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLW 748 C +NE + CELGNP KR ++ + G+++ T +L+V+L L+T S Q+ L Sbjct: 735 PLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQE-LH 793 Query: 749 PMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGL 808 P+ V L S++ + Q FF G V GE M++ DVGS +KYE V G+ L Sbjct: 794 PVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSL 853 Query: 809 VGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWP-----CRPPGDLINPLNLTLSDP 863 LG+ L + WP+E++NGKWLLYP ++ + G G P C P ++++ L++ Sbjct: 854 RTLGSAFLNIMWPHEIANGKWLLYPMQVELEG-GQGPGQKGLCSPRPNILH-LDV----- 906 Query: 864 GDRPSSPQRRRRQLDPGGGQGP-----PPVT---LAAAKKAKSETVLTCATGRAHCVWLE 915 S RRRR+L+P Q P P ++ +++A+K K+ T L CA G A+CV Sbjct: 907 ----DSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT-LDCARGTANCVVFS 961 Query: 916 CPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFS 975 CP+ + V R+WNSTF+E+Y + V A + +++SI + + + +T Sbjct: 962 CPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIP 1021 Query: 976 VDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023 V + + + + + W++L+AV AGLL+L L++LLLWK GFFKRA+ Sbjct: 1022 VMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1069 >gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] Length = 1141 Score = 619 bits (1597), Expect = e-177 Identities = 399/1072 (37%), Positives = 592/1072 (55%), Gaps = 111/1072 (10%) Query: 32 AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91 AFNLD + KE G PGSLFG+SVALHRQ + + + LL GAP+ LA+P NRTG + Sbjct: 33 AFNLDVMGALRKE-GEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGL 91 Query: 92 YLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPAGRVLVCAHRY------T 145 + CPL+ + DC R++I D E+ WLGV+V SQGP G+++ CAHRY Sbjct: 92 FACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVD 151 Query: 146 QVLWSGSEDQRRMVGKCYVRGNDL----ELDSSDDWQTYHNEMCNSNTD-YLETGMCQLG 200 Q+L + R M+G+C+V DL ELD +W + C + + G CQ G Sbjct: 152 QIL-----ETRDMIGRCFVLSQDLAIRDELDGG-EW-----KFCEGRPQGHEQFGFCQQG 200 Query: 201 TSGGFTQNTVY--FGAPGAYNWKGNSYM------------IQRKEWDLSEYSYKDPE--- 243 T+ F+ ++ Y FGAPG YNWKG + + + ++ +DP Sbjct: 201 TAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIP 260 Query: 244 DQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQV 303 N Y G+++ G ++ + ++ V GAPR H GAV +L +++ L +L G ++ Sbjct: 261 VPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERL 320 Query: 304 GAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHG 363 + FG ++A+ADLN+DGW DL+VGAPY+FER+EE+GGA+YV++NQ G P L L G Sbjct: 321 TSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISP-LRLCG 379 Query: 364 PSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLG 423 S FG+S+A +GD+NQDGF DIAVGAPF+G GKV+IYH SS G++ +P QV+ GE + Sbjct: 380 SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV- 438 Query: 424 LPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLVPRPAVLDP 482 G+ +FGYSLSG +D+D N YPDLLVGSL+D VL RARP++++ H+ ++ PR L+ Sbjct: 439 --GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQ 496 Query: 483 ALCTA--TSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR----PPRLRFAG--- 533 C + CV + +CF+Y A +Y + L Y L+AD DRR PR+ F Sbjct: 497 PNCAGGHSVCVDLRVCFSY--IAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNL 554 Query: 534 ----SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLR 589 +++ + C L +N++DKLR I+++++YSL R G Sbjct: 555 EEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQG 614 Query: 590 SLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQM-RAAFVSE-QQQKLSRLQYSR 646 PILN Q E+ F K+ CG D C+SNLQ+ RA F + + L Sbjct: 615 LPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDV 674 Query: 647 DVRKLL----------LSINVTNTRTS----ERSGEDAHEALLTLVVPPALLLSSVR--- 689 D L L + VTN + + G+DAHEA L +++P +L S VR Sbjct: 675 DGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALD 734 Query: 690 --PPGACQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQ 744 C +NE + CELGNP KR ++ + G+++ T +L+V+L L+T S Q Sbjct: 735 PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQ 794 Query: 745 DNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPM 804 + L P+ V L S++ + Q FF G V GE M++ DVGS +KYE V Sbjct: 795 E-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQ 853 Query: 805 GEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWP-----CRPPGDLINPLNLT 859 G+ L LG+ L + WP+E++NGKWLLYP ++ + G G P C P ++++ L++ Sbjct: 854 GQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEG-GQGPGQKGLCSPRPNILH-LDV- 910 Query: 860 LSDPGDRPSSPQRRRRQLDPGGGQGP-----PPVT---LAAAKKAKSETVLTCATGRAHC 911 S RRRR+L+P Q P P ++ +++A+K K+ T L CA G A+C Sbjct: 911 --------DSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT-LDCARGTANC 961 Query: 912 VWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKT 971 V CP+ + V R+WNSTF+E+Y + V A + +++SI + + + + Sbjct: 962 VVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDAS 1021 Query: 972 TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023 T V + + + + + W++L+AV AGLL+L L++LLLWK GFFKRA+ Sbjct: 1022 TVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1073 >gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] Length = 1044 Score = 522 bits (1344), Expect = e-148 Identities = 344/960 (35%), Positives = 520/960 (54%), Gaps = 102/960 (10%) Query: 140 CAHRYT------QVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNEMCNSNTD-YL 192 CAHRY Q+L + R M+G+C+V DL + D + + C + Sbjct: 43 CAHRYEARQRVDQIL-----ETRDMIGRCFVLSQDLAIRDELDGGEW--KFCEGRPQGHE 95 Query: 193 ETGMCQLGTSGGFTQNTVY--FGAPGAYNWKGNSYM------------IQRKEWDLSEYS 238 + G CQ GT+ F+ ++ Y FGAPG YNWKG + + + ++ Sbjct: 96 QFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEK 155 Query: 239 YKDPE---DQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRR 295 +DP N Y G+++ G ++ + ++ V GAPR H GAV +L +++ L Sbjct: 156 EQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPE 215 Query: 296 QVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPA 355 +L G ++ + FG ++A+ADLN+DGW DL+VGAPY+FER+EE+GGA+YV++NQ G Sbjct: 216 VMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGI 275 Query: 356 HPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQ 415 P L L G S FG+S+A +GD+NQDGF DIAVGAPF+G GKV+IYH SS G++ +P Q Sbjct: 276 SP-LRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQ 334 Query: 416 VIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLV 474 V+ GE + G+ +FGYSLSG +D+D N YPDLLVGSL+D VL RARP++++ H+ ++ Sbjct: 335 VLEGEAV---GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIA 391 Query: 475 PRPAVLDPALCTA--TSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR----PPR 528 PR L+ C + CV + +CF+Y A +Y + L Y L+AD DRR PR Sbjct: 392 PRSIDLEQPNCAGGHSVCVDLRVCFSY--IAVPSSYSPTVALDYVLDADTDRRLRGQVPR 449 Query: 529 LRFAG-------SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581 + F +++ + C L +N++DKLR I+++++YSL Sbjct: 450 VTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRL 509 Query: 582 DRPRLGLRSLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQM-RAAFVSE-QQQK 638 R G PILN Q E+ F K+ CG D C+SNLQ+ RA F + + Sbjct: 510 RRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE 569 Query: 639 LSRLQYSRDVRKLL----------LSINVTNTRTS----ERSGEDAHEALLTLVVPPALL 684 L D L L + VTN + + G+DAHEA L +++P +L Sbjct: 570 FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLH 629 Query: 685 LSSVR-----PPGACQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQL 736 S VR C +NE + CELGNP KR ++ + G+++ T +L+V+L Sbjct: 630 YSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVEL 689 Query: 737 QLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLK 796 L+T S Q+ L P+ V L S++ + Q FF G V GE M++ DVGS +K Sbjct: 690 LLATISEQE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVK 748 Query: 797 YEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWP-----CRPPGD 851 YE V G+ L LG+ L + WP+E++NGKWLLYP ++ + G G P C P + Sbjct: 749 YEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEG-GQGPGQKGLCSPRPN 807 Query: 852 LINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGP-----PPVT---LAAAKKAKSETVLT 903 +++ L++ S RRRR+L+P Q P P ++ +++A+K K+ T L Sbjct: 808 ILH-LDV---------DSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT-LD 856 Query: 904 CATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIP 963 CA G A+CV CP+ + V R+WNSTF+E+Y + V A + +++SI Sbjct: 857 CARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIK 916 Query: 964 TINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023 + + + +T V + + + + + W++L+AV AGLL+L L++LLLWK GFFKRA+ Sbjct: 917 NLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 976 >gi|49170034 integrin, alpha 8 [Homo sapiens] Length = 1063 Score = 289 bits (740), Expect = 8e-78 Identities = 307/1106 (27%), Positives = 491/1106 (44%), Gaps = 146/1106 (13%) Query: 1 MGPGPSRAPRAPRLMLCA-LALMVAAGGCVV-----SAFNLDTRFLVVKEAGNPGSLFGY 54 M PG SR PR + L A L AA G ++ AFNLD L V +G GS FGY Sbjct: 1 MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVY-SGPKGSYFGY 59 Query: 55 SVALHRQTERQQRYLLLAGAPR-ELAVPDGYTNRTGAVYLCPLTAHKD-DCERMNITVKN 112 +V H R +L GAP+ + PD GAVY CP A C ++ N Sbjct: 60 AVDFHIPDARTAS--VLVGAPKANTSQPDIVEG--GAVYYCPWPAEGSAQCRQIPFDTTN 115 Query: 113 DPGHHI------IE---DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSED--QRRMVGK 161 + + IE + W G TV + G+V+ CA Y W + ++ VG Sbjct: 116 NRKIRVNGTKEPIEFKSNQWFGATVKAH--KGKVVACAPLYH---WRTLKPTPEKDPVGT 170 Query: 162 CYVRGNDLELDSSDDWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQN-TVYFGAPGAYNW 220 CYV + + + NSN D G CQ G S F +N + G PG++ W Sbjct: 171 CYVAIQNFSAYAE------FSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYW 224 Query: 221 KGNSYMIQRKEWDL-SEYSYKD--------------PEDQGNLYIGYTMQVGSFILHPKN 265 +G +I D+ + YS+KD P + Y+GY++ G F + Sbjct: 225 QGQ--VITASVADIIANYSFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQ 282 Query: 266 ITIVTGAPRH-RHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDL 324 +V G PR ++ G V +++ D+ Q G Q+ +YFG + ++D+N+DG D+ Sbjct: 283 -ELVAGIPRGAQNFGYVSIINST---DMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDV 338 Query: 325 LVGAPYYFERKEEVG----GAIYVFMNQAGTSFPAHPSLLLHGPSGSAFGLSVASIGDIN 380 LVGAP + ER+ E G IY+++ + F P +L + FG ++A +GD+N Sbjct: 339 LVGAPLFMEREFESNPREVGQIYLYLQVSSLLF-RDPQILTGTETFGRFGSAMAHLGDLN 397 Query: 381 QDGFQDIAVGAPFEGL---GKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQ 437 QDG+ DIA+G PF G GKV IY+ + GL +P QV+ G + FG++L G Sbjct: 398 QDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGD 457 Query: 438 MDVDENFYPDLLVGSL-SDHIVLLRARPVINIVHKTLVPRPAVLD--------PALCTAT 488 D+D+N YPDL+VG+ + + + RARPV+ + + L+ P +++ P T+ Sbjct: 458 SDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLL-HPMIINLENKTCQVPDSMTSA 516 Query: 489 SCVQVELCFAYN-QSAGNPNYRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFFS 544 +C + +C + QS N I L ++ D ++ ++ F + A H F Sbjct: 517 ACFSLRVCASVTGQSIAN-----TIVLMAEVQLDSLKQKGAIKRTLFLDNHQA--HRVFP 569 Query: 545 MPEMR-----CQKLELLLMDN--LRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPIL 597 + R CQ + L D RDKL PI IS+NYSL L+ PIL Sbjct: 570 LVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLD------ESTFKEGLEVKPIL 623 Query: 598 NQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINV 657 N + + +CG DN C +L++ A ++ Q + D L+L IN Sbjct: 624 NYYRENIVSEQAHILVDCGEDNLCVPDLKLSAR--PDKHQVIIG-----DENHLMLIINA 676 Query: 658 TNTRTSERSGEDAHEALLTLVVPPALLLSSVRP------PGACQ-----ANETIFCELGN 706 N GE A+EA L +++P + P +C+ + C+LGN Sbjct: 677 RN------EGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGN 730 Query: 707 PFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTL--QTSL 764 P L + F V + + LQ+ SS++DN ++L ++ T Q + Sbjct: 731 PMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIR-SSNKDNPDSNFVSLQINITAVAQVEI 789 Query: 765 SMVNHRLQSFFG-GTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYE 823 V+H Q E E+VG +++ +++ +G + L +G WP+ Sbjct: 790 RGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVG--WPFS 847 Query: 824 VSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLT-LSDPGDRPSSPQRRRRQLDPGGG 882 + ++LLY I G C+P + INP ++ + P D P R P Sbjct: 848 ARD-EFLLYIFHIQTLG--PLQCQPNPN-INPQDIKPAASPEDTPELSAFLRNSTIPHLV 903 Query: 883 QGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIE 940 + V + + +L C C+ + C + + + V++R+W TF++ Sbjct: 904 R-KRDVHVVEFHRQSPAKILNCTN--IECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQ 960 Query: 941 DYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPA---EIELWLVLV 997 R D + + ++ +P + K S+ I + ++ P I LW++++ Sbjct: 961 --RKNDPYALASLVSFEVK-KMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIIL 1017 Query: 998 AVGAGLLLLGLIILLLWKCGFFKRAR 1023 A+ GLL+L ++ L LWKCGFF RAR Sbjct: 1018 AILLGLLVLAILTLALWKCGFFDRAR 1043 >gi|52485941 integrin, alpha 9 precursor [Homo sapiens] Length = 1035 Score = 275 bits (704), Expect = 1e-73 Identities = 274/1084 (25%), Positives = 477/1084 (44%), Gaps = 114/1084 (10%) Query: 4 GPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTE 63 GP+ A RL LAL+VA G A+NLD + V G S FGY+V H Sbjct: 3 GPAAPRGAGRLRALLLALVVA--GIPAGAYNLDPQ-RPVHFQGPADSFFGYAVLEHFHDN 59 Query: 64 RQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDD-CERMNITVKNDPG------- 115 + +L GAP+ + GAV+ C + + D C +++ + G Sbjct: 60 TRW---VLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTC 116 Query: 116 HHIIEDMWLGVTVASQGPA-GRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSS 174 +D W+GV++A Q A GRVL CAHR+ + + D G CY+ ++L+ Sbjct: 117 REDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEA--DHILPHGFCYIIPSNLQAKGR 174 Query: 175 DDWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDL 234 Y ++ G CQ G +G FT+ V GAPG++ W G ++ +L Sbjct: 175 TLIPCYEEYKKKYGEEH---GSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVL-----NL 226 Query: 235 SEYSYKDPEDQGNL-----YIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLL-SQEA 288 ++ +Y D+ + Y+GY + G F HP I +V GAP+ + +G V++ + Sbjct: 227 TDNTYLKLNDEVIMNRRYTYLGYAVTAGHFS-HPSTIDVVGGAPQDKGIGKVYIFRADRR 285 Query: 289 GGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQ 348 G L + G ++G+YFGS++ DLN DG DLLVGAP + E ++E G + V++N+ Sbjct: 286 SGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE--GQVTVYINR 343 Query: 349 AGTSFPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSS 406 + +L G + FG S+AS+ D++ DGF D+A+GAP E G VYIYH + Sbjct: 344 GNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDA 403 Query: 407 KGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGS-LSDHIVLLRARPV 465 G++ Q + G+K+ P L FG S+SG +D+D N YPD+ VG+ +SD +VLLRARPV Sbjct: 404 GGIVPQYSMKLSGQKIN-PVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPV 462 Query: 466 INIVHKTLVPRPAVLDPALC----TATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEAD 521 I + +P + C +C+ V CF+++ + I L Y L AD Sbjct: 463 ITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFH----GKHVPGEIGLNYVLMAD 518 Query: 522 RDRRP----PRLRFA------GSESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIIS 571 ++ PR+ F G + + E C+ + ++D + PI+ Sbjct: 519 VAKKEKGQMPRVYFVLLGETMGQVTEKLQ--LTYMEETCRHYVAHVKRRVQDVISPIVFE 576 Query: 572 MNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAF 631 YSL + L L + Q + + F++ C ++ C ++LQ++ Sbjct: 577 AAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED-CAADLQLQGKL 635 Query: 632 VSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPP 691 + + + V+ + L+I+++N G+DA++A ++ V L ++ Sbjct: 636 LLSSMDEKTLYLALGAVKNISLNISISNL------GDDAYDANVSFNVSRELFFINMWQK 689 Query: 692 G----ACQANETIF--CELGNPFKRNQ-RMELLIAFEVIGVTLHTRDLQ--VQLQLSTSS 742 +C+ E+ F C +G PF R++ + E + F+ ++ L V Q + Sbjct: 690 EEMGISCELLESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTE 749 Query: 743 HQDNLWPMILTLLVD--YTLQTSLSMVNHRLQSFFGGTVMGES--GMKTVEDVGSPLKYE 798 ++L L L+V + + TS++ + +G +V + + +E P+ Sbjct: 750 RSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINIT 809 Query: 799 FQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITV----HGNGSWPCRPPGDLIN 854 QV G L + + +P +S+G ++ + V GN S+ P +I Sbjct: 810 LQVYNTGPST--LPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCII- 866 Query: 855 PLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWL 914 PQ + T+ A VL C C+ Sbjct: 867 ---------------PQEQENIFH----------TIFAFFTKSGRKVLDCEKPGISCLTA 901 Query: 915 ECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWF 974 C + T+ + +T I ++ A + + ++ + + + Sbjct: 902 HCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNP-E 960 Query: 975 SVDIDSELVEELPAE--IELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKR 1032 V + E + L + W++ +++ G+L+ L+ +LLWK GFF+R R + + EA++ Sbjct: 961 EVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRR-RYKEIIEAEK 1019 Query: 1033 QKAE 1036 + E Sbjct: 1020 NRKE 1023 >gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] Length = 1048 Score = 270 bits (690), Expect = 5e-72 Identities = 301/1095 (27%), Positives = 476/1095 (43%), Gaps = 162/1095 (14%) Query: 9 PRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRY 68 PR L+L L L + AFNLD + +G GS FG++V + R Sbjct: 13 PRGLPLLLSGLLLPLCR------AFNLDVDS-PAEYSGPEGSYFGFAVDFFVPSA-SSRM 64 Query: 69 LLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITV-------KNDPGHHIIED 121 LL GAP+ G G V C ++ + C+ + K+DP Sbjct: 65 FLLVGAPKANTTQPGIVEG-GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDP-LEFKSH 121 Query: 122 MWLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRGNDLELDSSDDWQTY 180 W G +V S+ ++L CA Y W + + +R VG C+++ D +T Sbjct: 122 QWFGASVRSK--QDKILACAPLYH---WRTEMKQEREPVGTCFLQ---------DGTKTV 167 Query: 181 HNEMCNS-NTDYLETGMCQLGTSGGFTQ-NTVYFGAPGAYNWKGNSYMIQRKE----WDL 234 C S + D G CQ G S FT+ + V G PG++ W+G Q E +D Sbjct: 168 EYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDP 227 Query: 235 SEYSYKDPEDQG---------NLYIGYTMQVGSFILHPKNIT-IVTGAPRH-RHMGAVFL 283 + YS K + Y+GY++ VG F + I V+G PR R +G V++ Sbjct: 228 NVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDF--NGDGIDDFVSGVPRAARTLGMVYI 285 Query: 284 LSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER----KEEVG 339 G ++ G Q+ AYFG ++A D+N D + D+ +GAP + +R K + Sbjct: 286 YD---GKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEV 342 Query: 340 GAIYVFMNQAGTSFPAHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEGLGK 398 G + V + +A F + L+G A FG ++A +GD++QDGF DIA+ AP+ G K Sbjct: 343 GQVSVSLQRASGDFQ---TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDK 399 Query: 399 ---VYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLS- 454 VYI++ S GL P Q++ G+ +FGYS+ G D+D+N YPDL+VG+ Sbjct: 400 KGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGV 459 Query: 455 DHIVLLRARPVINIVHKTLVPRPAVLD--------PALCTATSCVQVELCFAYNQSAGNP 506 D +L RARPVI V+ L P++L+ P SC V C ++ G Sbjct: 460 DRAILYRARPVIT-VNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCL---KADGKG 515 Query: 507 NYRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFFSMPE---MRCQKLELLLMD- 559 R + L D+ ++ +R F S S ++ M+C++L L D Sbjct: 516 VLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDE 575 Query: 560 -NLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPD 618 RDKL PI I M Y L R GL+ PILNQ + +CG D Sbjct: 576 SEFRDKLTPITIFMEYRLDYRTA-ADTTGLQ-----PILNQFTPANISRQAHILLDCGED 629 Query: 619 NKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLV 678 N C+ L++ V Q+K+ Y D L L + N GE A+EA L + Sbjct: 630 NVCKPKLEVS---VDSDQKKI----YIGDDNPLTLIVKAQN------QGEGAYEAELIVS 676 Query: 679 VP-PALLLSSVRPPGAC--------QANET--IFCELGNPFKRNQRMELLIAFEVIGVTL 727 +P A + VR A N+T + C+LGNP K ++ + F V + Sbjct: 677 IPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSE 736 Query: 728 HTRDLQVQLQLSTSSHQDNLWPMI-----LTLLVDYTLQTSLSMVNHRLQSFFGGTVMGE 782 ++ LQ+ +S+ D + P++ L +L ++ +S +H + Sbjct: 737 MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIR-GVSSPDHIFLPI--PNWEHK 793 Query: 783 SGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNG 842 +T EDVG +++ +++ G +L L+WPY+ +N LLY + G Sbjct: 794 ENPETEEDVGPVVQHIYEL--RNNGPSSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG-- 848 Query: 843 SWPCRPPGDL-INPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSE-T 900 P D+ INPL + +S + + D GQG + A SE Sbjct: 849 --PMNCTSDMEINPLRIKISS--------LQTTEKNDTVAGQGERDHLITKRDLALSEGD 898 Query: 901 VLTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL-- 956 + T G A C+ + C + D + VK+ +W TF+ + A+ Sbjct: 899 IHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNV 958 Query: 957 --FLRTSIPTINMENKT------TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGL 1008 F ++P ++ N T TW ++ P + +W++++AV AGLLLL + Sbjct: 959 IEFPYKNLPIEDITNSTLVTTNVTWG--------IQPAPMPVPVWVIILAVLAGLLLLAV 1010 Query: 1009 IILLLWKCGFFKRAR 1023 ++ ++++ GFFKR R Sbjct: 1011 LVFVMYRMGFFKRVR 1025 >gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] Length = 1039 Score = 269 bits (687), Expect = 1e-71 Identities = 303/1074 (28%), Positives = 466/1074 (43%), Gaps = 158/1074 (14%) Query: 32 AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91 A NLD L AG GS FG+S+ H+ + R ++ GAPR L TG V Sbjct: 31 ALNLDPVQLTFY-AGPNGSQFGFSLDFHKDSHG--RVAIVVGAPRTLGPSQ---EETGGV 84 Query: 92 YLCPLTAHKDDCERMNITVKNDP---GHHIIEDM----WLGVTVASQGPAGRVLVCAH-R 143 +LCP A C + ++++ G ++ LG +V S ++ CA + Sbjct: 85 FLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDV--IVACAPWQ 142 Query: 144 YTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNEMCNSNT---DYLETGM---- 196 + VL E ++ VG C+ L + + C NT Y+E Sbjct: 143 HWNVLEKTEEAEKTPVGSCF-------LAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195 Query: 197 --CQLGTSGGFTQ-NTVYFGAPGAYNWKG-----------NSYMIQRKEWDLSEYSYKDP 242 C+ G S TQ + GAPG Y + G +SY W +S S Sbjct: 196 RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255 Query: 243 EDQGNL---YIGYTMQVGSFILHPKNITIVTGAPRHRH-MGAVFLLSQEAGGDLRRRQVL 298 Y GY++ VG F V GAP +GAV +L +R L Sbjct: 256 SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY----YQRLHRL 311 Query: 299 EGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFE----RKEEVGGAIYVFMNQAGTSFP 354 G Q+ +YFG ++A+ D+N DG DLLVGAP Y E RK G +Y+F+ G Sbjct: 312 RGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHAL 371 Query: 355 AHPSLLLHGPS-GSAFGLSVASIGDINQDGFQDIAVGAPF---EGLGKVYIYHSSSKGLL 410 PSLLL G FG ++A +GD+++DG+ DIAV AP+ G G+V ++ S+GL Sbjct: 372 GAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLR 431 Query: 411 RQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSL-SDHIVLLRARPVINIV 469 +P QV+ P + FG+SL G +D+D+N YPDL+VG+ ++ + + RA+PV+ Sbjct: 432 SRPSQVLDSP---FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKAS 488 Query: 470 HKTLVP---RPAVLD---PALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRD 523 + LV PAV P T SC +++C A N + ++L L+ DR Sbjct: 489 VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCV----GATGHNIPQKLSLNAELQLDRQ 544 Query: 524 --RRPPRLRFAGSESA---VFHGFFSMPEMRCQKLELLLMD--NLRDKLRPIIISMNYSL 576 R+ R+ GS+ A + C L D + RDKL PI++S+N SL Sbjct: 545 KPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSL 604 Query: 577 PLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQK----ECGPDNKCESNLQMRAAFV 632 P P + A L T VQ Q +CG D+ C LQ+ A+ Sbjct: 605 P---PTEAGMA-----------PAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVT 650 Query: 633 SEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL----LLSSV 688 S L D L L ++ N GE A+EA L + +P LS+V Sbjct: 651 G------SPLLVGAD-NVLELQMDAAN------EGEGAYEAELAVHLPQGAHYMRALSNV 697 Query: 689 RP-----PGACQANET--IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTS 741 + NET + CELGNP K+N ++ + + V + + QLQ+ + Sbjct: 698 EGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSK 757 Query: 742 SHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM----GESGMKTVEDVGSPLKY 797 + Q+ P +L+D ++ + V R SF V+ GE +++ G +++ Sbjct: 758 NSQN---PNSKIVLLDVPVRAE-AQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEH 813 Query: 798 EFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLN 857 +++ G G V L L + P + S LLY +I G +PP +NPL Sbjct: 814 TYELHNNGPGTV--NGLHLSIHLPGQ-SQPSDLLYILDIQPQGGLQCFPQPP---VNPLK 867 Query: 858 LT--LSDPGDRPSSP---QRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCV 912 + L P P P +R RRQ+ + P + + +++C + A C Sbjct: 868 VDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQP--------SRLQDPVLVSCDS--APCT 917 Query: 913 WLECPIPDAP--VVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL-FLRTSIPTINMEN 969 ++C + + VTV A +W + + D ++ + W + L ++P +++ Sbjct: 918 VVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPR 977 Query: 970 KTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023 + L E I +W VLV V GLLLL +++L +WK GFFKR R Sbjct: 978 GEAQVWTQLLRALEER---AIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028 >gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] Length = 1002 Score = 260 bits (665), Expect = 4e-69 Identities = 284/1037 (27%), Positives = 452/1037 (43%), Gaps = 154/1037 (14%) Query: 67 RYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITV-------KNDPGHHII 119 R LL GAP+ G G V C ++ + C+ + K+DP Sbjct: 17 RMFLLVGAPKANTTQPGIVEG-GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDP-LEFK 73 Query: 120 EDMWLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRGNDLELDSSDDWQ 178 W G +V S+ ++L CA Y W + + +R VG C+++ D + Sbjct: 74 SHQWFGASVRSK--QDKILACAPLYH---WRTEMKQEREPVGTCFLQ---------DGTK 119 Query: 179 TYHNEMCNS-NTDYLETGMCQLGTSGGFTQ-NTVYFGAPGAYNWKGNSYMIQRKE----W 232 T C S + D G CQ G S FT+ + V G PG++ W+G Q E + Sbjct: 120 TVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKY 179 Query: 233 DLSEYSYKDPEDQG---------NLYIGYTMQVGSFILHPKNIT-IVTGAPRH-RHMGAV 281 D + YS K + Y+GY++ VG F + I V+G PR R +G V Sbjct: 180 DPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDF--NGDGIDDFVSGVPRAARTLGMV 237 Query: 282 FLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER----KEE 337 ++ G ++ G Q+ AYFG ++A D+N D + D+ +GAP + +R K + Sbjct: 238 YIYD---GKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQ 294 Query: 338 VGGAIYVFMNQAGTSFPAHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEGL 396 G + V + +A F + L+G A FG ++A +GD++QDGF DIA+ AP+ G Sbjct: 295 EVGQVSVSLQRASGDFQ---TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGE 351 Query: 397 GK---VYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSL 453 K VYI++ S GL P Q++ G+ +FGYS+ G D+D+N YPDL+VG+ Sbjct: 352 DKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAF 411 Query: 454 S-DHIVLLRARPVINIVHKTLVPRPAVLD--------PALCTATSCVQVELCFAYNQSAG 504 D +L RARPVI V+ L P++L+ P SC V C ++ G Sbjct: 412 GVDRAILYRARPVIT-VNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCL---KADG 467 Query: 505 NPNYRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFFSMPE---MRCQKLELLLM 558 R + L D+ ++ +R F S S ++ M+C++L L Sbjct: 468 KGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLR 527 Query: 559 D--NLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECG 616 D RDKL PI I M Y L R GL+ PILNQ + +CG Sbjct: 528 DESEFRDKLTPITIFMEYRLDYRTA-ADTTGLQ-----PILNQFTPANISRQAHILLDCG 581 Query: 617 PDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLT 676 DN C+ L++ V Q+K+ Y D L L + N GE A+EA L Sbjct: 582 EDNVCKPKLEVS---VDSDQKKI----YIGDDNPLTLIVKAQN------QGEGAYEAELI 628 Query: 677 LVVP-PALLLSSVRPPGAC--------QANET--IFCELGNPFKRNQRMELLIAFEVIGV 725 + +P A + VR A N+T + C+LGNP K ++ + F V Sbjct: 629 VSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQ 688 Query: 726 TLHTRDLQVQLQLSTSSHQDNLWPMI-----LTLLVDYTLQTSLSMVNHRLQSFFGGTVM 780 + ++ LQ+ +S+ D + P++ L +L ++ +S +H Sbjct: 689 SEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIR-GVSSPDHIFLPI--PNWE 745 Query: 781 GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG 840 + +T EDVG +++ +++ G +L L+WPY+ +N LLY + G Sbjct: 746 HKENPETEEDVGPVVQHIYEL--RNNGPSSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG 802 Query: 841 NGSWPCRPPGDL-INPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSE 899 P D+ INPL + +S + + D GQG + A SE Sbjct: 803 ----PMNCTSDMEINPLRIKISS--------LQTTEKNDTVAGQGERDHLITKRDLALSE 850 Query: 900 -TVLTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL 956 + T G A C+ + C + D + VK+ +W TF+ + A+ Sbjct: 851 GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASF 910 Query: 957 ----FLRTSIPTINMENKT------TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLL 1006 F ++P ++ N T TW ++ P + +W++++AV AGLLLL Sbjct: 911 NVIEFPYKNLPIEDITNSTLVTTNVTWG--------IQPAPMPVPVWVIILAVLAGLLLL 962 Query: 1007 GLIILLLWKCGFFKRAR 1023 +++ ++++ GFFKR R Sbjct: 963 AVLVFVMYRMGFFKRVR 979 >gi|56237029 integrin alpha 5 precursor [Homo sapiens] Length = 1049 Score = 258 bits (660), Expect = 2e-68 Identities = 306/1109 (27%), Positives = 462/1109 (41%), Gaps = 158/1109 (14%) Query: 4 GPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTE 63 GP R P L+L L GG FNLD V +G PGS FG+SV +R Sbjct: 18 GPRRRPPLLPLLLLLLPPPPRVGG-----FNLDAEAPAVL-SGPPGSFFGFSVEFYRPGT 71 Query: 64 RQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIED-- 121 +L GAP+ G + GAVYLCP A C + K G ++E Sbjct: 72 --DGVSVLVGAPKANTSQPGVL-QGGAVYLCPWGASPTQCTPIEFDSK---GSRLLESSL 125 Query: 122 --------------MWLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRG 166 W G TV + G + +L CA Y+ W + E VG CY+ Sbjct: 126 SSSEGEEPVEYKSLQWFGATVRAHGSS--ILACAPLYS---WRTEKEPLSDPVGTCYL-- 178 Query: 167 NDLELDSSDDW-QTYHNEMCNSNTDYLE-TGMCQLGTSGGFTQN-TVYFGAPGAYNWKGN 223 S+D++ + C S+ + G CQ G S FT+ V G PG+Y W+G Sbjct: 179 ------STDNFTRILEYAPCRSDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQ 232 Query: 224 SYMIQRKEWDLSEY-SYKDPEDQGNL------------YIGYTMQVGSFILHPKNITIVT 270 +++ S Y Y QG L Y+GY++ VG F V Sbjct: 233 ILSATQEQIAESYYPEYLINLVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTE-DFVA 291 Query: 271 GAPR-HRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAP 329 G P+ + G V +L+ G D+R G Q+ +YFG A+A D+N DG DLLVGAP Sbjct: 292 GVPKGNLTYGYVTILN---GSDIRSLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAP 348 Query: 330 YYFER----KEEVGGAIYVFMNQAGTSFPAHPSLLLHG-PSGSAFGLSVASIGDINQDGF 384 +R + + G +YV++ P P+L L G FG S+ +GD++QDG+ Sbjct: 349 LLMDRTPDGRPQEVGRVYVYLQHPAGIEPT-PTLTLTGHDEFGRFGSSLTPLGDLDQDGY 407 Query: 385 QDIAVGAPFEG---LGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVD 441 D+A+GAPF G G V+++ GL +P QV+ FG +L G D+D Sbjct: 408 NDVAIGAPFGGETQQGVVFVFPGGPGGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLD 467 Query: 442 ENFYPDLLVGSLS-DHIVLLRARPVINIVHKTLVPRPAVLDP--ALCT----ATSCVQVE 494 N YPDL+VGS D V+ R RP+++ +L PA+ +P C+ +C+ + Sbjct: 468 GNGYPDLIVGSFGVDKAVVYRGRPIVS-ASASLTIFPAMFNPEERSCSLEGNPVACINLS 526 Query: 495 LCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFF-----SMP 546 C +A + +I L+ D ++ +R F S A + Sbjct: 527 FCL----NASGKHVADSIGFTVELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGARE 582 Query: 547 EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENH 606 + R K+ L RDKL PI I++N+SL + P GLR P L+ Sbjct: 583 DCREMKIYLRNESEFRDKLSPIHIALNFSLDPQAPVDSH-GLR-----PALHYQSKSRIE 636 Query: 607 TEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERS 666 + Q +CG DN C +LQ+ EQ Y D L L+ + N Sbjct: 637 DKAQILLDCGEDNICVPDLQLEV--FGEQNH-----VYLGDKNALNLTFHAQNV------ 683 Query: 667 GE-DAHEALLTLVVPPALLLSS-VRPPG----------ACQANETIFCELGNPFKRNQRM 714 GE A+EA L + PP S VR PG A + + C+LGNP K + Sbjct: 684 GEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLLVCDLGNPMKAGASL 743 Query: 715 ELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMI-LTLLVDYTLQTSLSMVNHRLQS 773 + F V + + +Q Q+ + + ++ ++ L V+ Q +L+ V+ Sbjct: 744 WGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSVEAQAQVTLNGVSKPEAV 803 Query: 774 FFGGTVMGESGM-KTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLY 832 F + + ED+G + + +++ G + G L L E G+ LLY Sbjct: 804 LFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPSSISQGVLELSCPQALE---GQQLLY 860 Query: 833 PTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAA 892 T +T G P INP L L DP Q+R GP Sbjct: 861 VTRVT--GLNCTTNHP----INPKGLEL-DPEGSLHHQQKREAPSRSSASSGP------- 906 Query: 893 AKKAKSETVLTCATGRAHCVWLECPIPDAPVVTNVTVKA--RVWNSTFIE-DYRDFDRVR 949 +L C A C L C + + +++ RVW TF++ +++ F Sbjct: 907 -------QILKCP--EAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQPFSLQC 957 Query: 950 VNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLI 1009 + L + I + K + + E + LW++++A+ GLLLLGL+ Sbjct: 958 EAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEG-SYGVPLWIIILAILFGLLLLGLL 1016 Query: 1010 ILLLWKCGFFKRARTRALYEAKRQKAEMK 1038 I +L+K GFFKR+ Y +KA++K Sbjct: 1017 IYILYKLGFFKRSLP---YGTAMEKAQLK 1042 >gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] Length = 1012 Score = 248 bits (634), Expect = 2e-65 Identities = 287/1080 (26%), Positives = 463/1080 (42%), Gaps = 168/1080 (15%) Query: 9 PRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRY 68 PR L+L L L + AFNLD + +G GS FG++V + R Sbjct: 13 PRGLPLLLSGLLLPLCR------AFNLDVDS-PAEYSGPEGSYFGFAVDFFVPSA-SSRM 64 Query: 69 LLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITV-------KNDPGHHIIED 121 LL GAP+ G G V C ++ + C+ + K+DP Sbjct: 65 FLLVGAPKANTTQPGIVEG-GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDP-LEFKSH 121 Query: 122 MWLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRGNDLELDSSDDWQTY 180 W G +V S+ ++L CA Y W + + +R VG C+++ D +T Sbjct: 122 QWFGASVRSK--QDKILACAPLYH---WRTEMKQEREPVGTCFLQ---------DGTKTV 167 Query: 181 HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK 240 C S + + ++ + P Y+ K N+ + R + + SY Sbjct: 168 EYAPCRSR-QLISDQVAEIVSKYD----------PNVYSIKYNNQLATRTAQAIFDDSY- 215 Query: 241 DPEDQGNLYIGYTMQVGSFILHPKNIT-IVTGAPRH-RHMGAVFLLSQEAGGDLRRRQVL 298 +GY++ VG F + I V+G PR R +G V++ G ++ Sbjct: 216 ---------LGYSVAVGDF--NGDGIDDFVSGVPRAARTLGMVYIYD---GKNMSSLYNF 261 Query: 299 EGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER----KEEVGGAIYVFMNQAGTSFP 354 G Q+ AYFG ++A D+N D + D+ +GAP + +R K + G + V + +A F Sbjct: 262 TGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQ 321 Query: 355 AHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEGLGK---VYIYHSSSKGLL 410 + L+G A FG ++A +GD++QDGF DIA+ AP+ G K VYI++ S GL Sbjct: 322 ---TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLN 378 Query: 411 RQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLS-DHIVLLRARPVINIV 469 P Q++ G+ +FGYS+ G D+D+N YPDL+VG+ D +L RARPVI V Sbjct: 379 AVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVIT-V 437 Query: 470 HKTLVPRPAVLD--------PALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEAD 521 + L P++L+ P SC V C ++ G R + L D Sbjct: 438 NAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCL---KADGKGVLPRKLNFQVELLLD 494 Query: 522 RDRRPPRLR---FAGSESAVFHGFFSMPE---MRCQKLELLLMD--NLRDKLRPIIISMN 573 + ++ +R F S S ++ M+C++L L D RDKL PI I M Sbjct: 495 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 554 Query: 574 YSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVS 633 Y L R GL+ PILNQ + +CG DN C+ L++ V Sbjct: 555 YRLDYRTA-ADTTGLQ-----PILNQFTPANISRQAHILLDCGEDNVCKPKLEVS---VD 605 Query: 634 EQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVP-PALLLSSVRPPG 692 Q+K+ Y D L L + N GE A+EA L + +P A + VR Sbjct: 606 SDQKKI----YIGDDNPLTLIVKAQN------QGEGAYEAELIVSIPLQADFIGVVRNNE 655 Query: 693 AC--------QANET--IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSS 742 A N+T + C+LGNP K ++ + F V + ++ LQ+ +S+ Sbjct: 656 ALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSN 715 Query: 743 HQDNLWPMI-----LTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKY 797 D + P++ L +L ++ +S +H + +T EDVG +++ Sbjct: 716 LFDKVSPVVSHKVDLAVLAAVEIR-GVSSPDHIFLPI--PNWEHKENPETEEDVGPVVQH 772 Query: 798 EFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDL-INPL 856 +++ G +L L+WPY+ +N LLY + G P D+ INPL Sbjct: 773 IYEL--RNNGPSSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG----PMNCTSDMEINPL 825 Query: 857 NLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSE-TVLTCATGRAHCVWLE 915 + +S + + D GQG + A SE + T G A C+ + Sbjct: 826 RIKISS--------LQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIV 877 Query: 916 CPIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL----FLRTSIPTINMEN 969 C + D + VK+ +W TF+ + A+ F ++P ++ N Sbjct: 878 CQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITN 937 Query: 970 KT------TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023 T TW ++ P + +W++++AV AGLLLL +++ ++++ GFFKR R Sbjct: 938 STLVTTNVTWG--------IQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVR 989 >gi|67191027 integrin alpha 4 precursor [Homo sapiens] Length = 1032 Score = 245 bits (625), Expect = 2e-64 Identities = 223/805 (27%), Positives = 379/805 (47%), Gaps = 76/805 (9%) Query: 3 PGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQT 62 PGP RA +ML L L V G +N+DT ++ + G +LFGYSV LH Sbjct: 9 PGPRRAAVRETVMLL-LCLGVPTG----RPYNVDTESALLYQ-GPHNTLFGYSVVLHSHG 62 Query: 63 ERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDD-CERMNITVKNDP--GHHII 119 + LL GAP + + GA+Y C + + CE++ + N G + Sbjct: 63 ANRW---LLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCL 119 Query: 120 ED---MWLGVTVASQ-GPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSD 175 E+ WLGVT++ Q G G ++ C HR+ + + +E+ + G CY DL + S Sbjct: 120 EERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNEN-KLPTGGCYGVPPDLRTELSK 178 Query: 176 DWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLS 235 + + + + CQ G S +T++ + GAPG+ W G+ ++ Sbjct: 179 RIAPCYQDYVKKFGENFAS--CQAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYK 236 Query: 236 EYSYKDPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRR 295 + K + + Y+GY++ G F +V GAP+H +G ++ S + +L Sbjct: 237 AFLDKQNQVKFGSYLGYSVGAGHF-RSQHTTEVVGGAPQHEQIGKAYIFSIDEK-ELNIL 294 Query: 296 QVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQ-AGTSFP 354 ++G ++G+YFG+++ DLN DG+ DLLVGAP +EE G ++V++N +G Sbjct: 295 HEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREE--GRVFVYINSGSGAVMN 352 Query: 355 AHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSSKGLLR 411 A + L+ +A FG S+ ++GDI+ DGF+D+A+GAP E G +YIY+ + G+ Sbjct: 353 AMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISS 412 Query: 412 QPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSL-SDHIVLLRARPVINIVH 470 Q I G ++ L+ FG S+SGQ+D D N Y D+ VG+ SD VLLR RPV+ + Sbjct: 413 TFSQRIEGLQIS-KSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDA 471 Query: 471 KTLVPRPAVLDPALCTATS----CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR- 525 P C C+ + LCF+Y + P Y I L Y + D +R+ Sbjct: 472 SLSHPESVNRTKFDCVENGWPSVCIDLTLCFSY-KGKEVPGY---IVLFYNMSLDVNRKA 527 Query: 526 --PPRLRFAGS-ESAVFHGFF--SMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRM 580 PPR F+ + S V G S E C+ + + ++RD L PI I Y L + Sbjct: 528 ESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHV 587 Query: 581 PDRPRLGLRSLDAY----PILNQAQALE-NHTEVQFQKECGPDNKCESNLQMRA--AFVS 633 + RS + + PIL Q + + + F + C +N C ++LQ+ A F+ Sbjct: 588 -----ISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLK 641 Query: 634 EQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL----LLSSVR 689 + K S ++ L+L++++ N +G+DA+E L + +P L +L Sbjct: 642 PHENKTYLAVGS--MKTLMLNVSLFN------AGDDAYETTLHVKLPVGLYFIKILELEE 693 Query: 690 PPGACQANET-----IFCELGNPFKRN-QRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH 743 C+ + + C +G + + R+++ +V ++ DL + + + + Sbjct: 694 KQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENE 753 Query: 744 Q--DNLWPMILTLLVDYTLQTSLSM 766 + DNL +T+ + + L++ Sbjct: 754 EEMDNLKHSRVTVAIPLKYEVKLTV 778 Score = 34.3 bits (77), Expect = 0.63 Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 5/42 (11%) Query: 997 VAVGAGLLLLGLIILLL-----WKCGFFKRARTRALYEAKRQ 1033 + + + LLLGLI+LLL WK GFFKR L E R+ Sbjct: 978 IVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRR 1019 >gi|31657142 integrin, alpha 1 precursor [Homo sapiens] Length = 1179 Score = 233 bits (593), Expect = 9e-61 Identities = 225/871 (25%), Positives = 369/871 (42%), Gaps = 115/871 (13%) Query: 193 ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGN------SYMIQRKEWDLSEYSYKDPEDQG 246 E M Q G S ++Q+ V GA GAY+W G S +I + + S K E Sbjct: 374 EMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLA 433 Query: 247 NLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAY 306 + Y+GYT V S ++ + G PR+ H G V + E G+++ Q L G Q+G+Y Sbjct: 434 S-YLGYT--VNSATASSGDVLYIAGQPRYNHTGQVIIYRME-DGNIKILQTLSGEQIGSY 489 Query: 307 FGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVF---------------MNQAG 350 FGS + D++ D D LLVGAP Y ++E G +YV+ + Q Sbjct: 490 FGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTC 549 Query: 351 TSFPAHPSLLLHG---PSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSS 405 S H S P G+ FG ++A++ D+N DGF DI +GAP E G VYIYH S Sbjct: 550 CSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGS 609 Query: 406 SKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPV 465 K + ++ Q I G L FG S+ G+MD++ + D+ +G L + Sbjct: 610 GKTIRKEYAQRIPSGGDG-KTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVA 668 Query: 466 INIVHKTLVPRPAVLDPALC----TATSCVQVELCFAYN-QSAGNPNYRRNITLAYTLEA 520 + V P + C T C+ +CF +S + Y + L Y + Sbjct: 669 VVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEAD--LQYRVTL 726 Query: 521 DRDRRPPRLRFAGSESAVFHGFFSMPEMRCQKLELLLMD--NLRDKLRPIIISMNYSLPL 578 D R+ R F+G++ ++ + C K ++D + +D +R I+++++L Sbjct: 727 DSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDFNL-- 781 Query: 579 RMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQK 638 P G P+L+ + H + F K+CG KC S+L + A +E+ Sbjct: 782 ---TDPENG-------PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVA-TTEKDLL 830 Query: 639 LSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVR--PPGACQA 696 + R Q K +S+ V NT+ S A+ + P L+ S + +C++ Sbjct: 831 IVRSQND----KFNVSLTVKNTKDS------AYNTRTIVHYSPNLVFSGIEAIQKDSCES 880 Query: 697 NETIFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQ------DNLWPM 750 N I C++G PF R M + ++ + L ++ S + DN+ + Sbjct: 881 NHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNI 940 Query: 751 ILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVG 810 + + + LQ S + + TV + + ED+G+ + + + G Sbjct: 941 SIPVKYEVGLQFYSSASEYHISIAANETV--PEVINSTEDIGNEINIFYLIRKSGS--FP 996 Query: 811 LGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSP 870 + L L + +P SNG +LYPT ++ N + CRP DP S Sbjct: 997 MPELKLSISFPNMTSNGYPVLYPTGLSSSENAN--CRPH---------IFEDPFSINSGK 1045 Query: 871 QRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVTNVTVK 930 + + K T+L C T + + D ++ V V Sbjct: 1046 K-----------------MTTSTDHLKRGTILDCNTCKFATITCNLTSSD---ISQVNVS 1085 Query: 931 ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990 +W TFI+ Y F + + L + ++ N+ ++ I + LP + Sbjct: 1086 LILWKPTFIKSY--FSSLNLTIRGELRSENASLVLSSSNQKRELAIQISK---DGLPGRV 1140 Query: 991 ELWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021 LW++L++ AGLLLL L+IL LWK GFFKR Sbjct: 1141 PLWVILLSAFAGLLLLMLLILALWKIGFFKR 1171 Score = 39.7 bits (91), Expect = 0.015 Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 16/147 (10%) Query: 1 MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR 60 M P P P + C L V CV +FN+D + + +G +FGY+V + Sbjct: 1 MAPRPRARPGVA--VACCWLLTVVLRCCV--SFNVDVKNSMTF-SGPVEDMFGYTV---Q 52 Query: 61 QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKD-DCERMNITVKNDPGH--H 117 Q E ++ +L G+P + P NRTG VY CP+ + C ++++ V + Sbjct: 53 QYENEEGKWVLIGSPL-VGQPK---NRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTE 108 Query: 118 IIEDMWLGVTVASQGPAGRVLVCAHRY 144 + E+M G T+ + P G L C Y Sbjct: 109 VKENMTFGSTLVT-NPNGGFLACGPLY 134 >gi|38569398 integrin, alpha 10 precursor [Homo sapiens] Length = 1167 Score = 179 bits (453), Expect = 2e-44 Identities = 158/592 (26%), Positives = 268/592 (45%), Gaps = 55/592 (9%) Query: 196 MCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNL-----YI 250 M Q+G S ++ + FG GAY+W G+ ++ + E L Y+ Sbjct: 372 MSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYL 431 Query: 251 GYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSA 310 GY+ V S +L ++GAPR RH G V + G +R Q L+G Q+G+YFGS Sbjct: 432 GYS--VSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSE 489 Query: 311 IALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSGSAF 369 + D + DG D LLV AP + + + G +YV++ + +L P + F Sbjct: 490 LCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARF 549 Query: 370 GLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGL 427 G ++ ++ D+NQDGF D+AVGAP E G +Y+YH + G+ P Q I + L Sbjct: 550 GFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMP-HAL 608 Query: 428 ATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLVPRPAVLDPALCT 486 + FG S+ G++D+D + D+ VG+ +LL +RP++++ + P+ + C Sbjct: 609 SYFGRSVDGRLDLDGDDLVDVAVGA-QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCR 667 Query: 487 ATS----CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVF--H 540 C+ LCF S + + +T D R F GS + Sbjct: 668 RRGQEAVCLTAALCFQVT-SRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRLSPRR 726 Query: 541 GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA 600 S+ + C++L ++D D LRP+ +++ ++L + P+LN+ Sbjct: 727 LRLSVGNVTCEQLHFHVLDT-SDYLRPVALTVTFALD-----------NTTKPGPVLNEG 774 Query: 601 QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT 660 V F K+CGPDN+C ++L ++ +K + RK+L+S + N Sbjct: 775 SPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRK-APFVVRGGRRKVLVSTTLENR 833 Query: 661 RTSERSGEDAHEALLTLVVPPALLLSSVRPPG--------ACQANETIFCELGNP-FKRN 711 + E+A+ L+L+ L L+S+ P A + C +G+P F+ Sbjct: 834 K------ENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTG 887 Query: 712 QRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTS 763 ++ L+ FE +L ++ + V+L S+ S + N L D T QTS Sbjct: 888 AKVTFLLEFEFSCSSLLSQ-VFVKLTASSDSLERN------GTLQDNTAQTS 932 Score = 44.7 bits (104), Expect = 5e-04 Identities = 23/54 (42%), Positives = 34/54 (62%), Gaps = 2/54 (3%) Query: 981 ELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQK 1034 E+V+ P I LW+++ +V GLLLL L++ LWK GFF A + E KR++ Sbjct: 1112 EVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFF--AHKKIPEEEKREE 1163 >gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] Length = 1086 Score = 176 bits (445), Expect = 1e-43 Identities = 159/558 (28%), Positives = 253/558 (45%), Gaps = 62/558 (11%) Query: 200 GTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSY-----KDPEDQGNLYIGYTM 254 G S ++ GA GA +W G ++ DL + ++ PE + Y+GYT Sbjct: 270 GISADLSRGHAVVGAVGAKDWAGGFLDLKA---DLQDDTFIGNEPLTPEVRAG-YLGYT- 324 Query: 255 QVGSFILHPKNITIVTGAPRHRHMGAVFLLSQ-EAGGDLRRRQVLEGSQVGAYFGSAIAL 313 V K + +GAPR++HMG V L + + GG + Q + G+Q+G+YFG + Sbjct: 325 -VTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCG 383 Query: 314 ADLNNDGWQDLL-VGAPYYFERKEEVGGAIYVFMN-QAGTSFPAHPSLLLHGPSG---SA 368 D++ DG +LL +GAP ++ E+ GG ++++ Q G + L G G Sbjct: 384 VDVDQDGETELLLIGAPLFYG--EQRGGRVFIYQRRQLGFEEVSE----LQGDPGYPLGR 437 Query: 369 FGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLA 428 FG ++ ++ DIN DG D+AVGAP E G VYI++ GL QP Q I G ++ L G+ Sbjct: 438 FGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQV-LSGIQ 496 Query: 429 TFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVH-KTLVPRPAVLDPALCTA 487 FG S+ G D++ + D+ VG+ S IV L +RPV+++V + P + C+ Sbjct: 497 WFGRSIHGVKDLEGDGLADVAVGAESQMIV-LSSRPVVDMVTLMSFSPAEIPVHEVECSY 555 Query: 488 TSC------VQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFHG 541 ++ V + +CF R L YTL+ D R R F G + Sbjct: 556 STSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRN 615 Query: 542 FFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQ 601 M C ++D + PI +S+N+SL PR D PIL + Sbjct: 616 IAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSL-WEEEGTPRDQRAGKDIPPILRPSL 674 Query: 602 ALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTR 661 E E+ F+K CG D KCE+NL R +F + + L ++ L + ++++N Sbjct: 675 HSET-WEIPFEKNCGEDKKCEANL--RVSFSPARSRALRLTAFA----SLSVELSLSNLE 727 Query: 662 TSERSGEDAHEALLTLVVPPALLLSSV-------RPPGACQ--------ANETIFCELGN 706 EDA+ L L PP L V + P +C+ + + C + + Sbjct: 728 ------EDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSS 781 Query: 707 P-FKRNQRMELLIAFEVI 723 P FK + L + F + Sbjct: 782 PIFKAGHSVALQMMFNTL 799 Score = 32.3 bits (72), Expect = 2.4 Identities = 16/30 (53%), Positives = 23/30 (76%) Query: 992 LWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021 L+L +++ GLLLL LI ++L+K GFFKR Sbjct: 1006 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1035 >gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] Length = 1170 Score = 173 bits (439), Expect = 7e-43 Identities = 157/558 (28%), Positives = 252/558 (45%), Gaps = 61/558 (10%) Query: 200 GTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSY-----KDPEDQGNLYIGYTM 254 G S ++ GA GA +W G ++ DL + ++ PE + Y+GYT Sbjct: 353 GISADLSRGHAVVGAVGAKDWAGGFLDLKA---DLQDDTFIGNEPLTPEVRAG-YLGYT- 407 Query: 255 QVGSFILHPKNITIVTGAPRHRHMGAVFLLSQ-EAGGDLRRRQVLEGSQVGAYFGSAIAL 313 V K + +GAPR++HMG V L + + GG + Q + G+Q+G+YFG + Sbjct: 408 -VTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCG 466 Query: 314 ADLNNDGWQDLL-VGAPYYFERKEEVGGAIYVFMN-QAGTSFPAHPSLLLHGPSG---SA 368 D++ DG +LL +GAP ++ E+ GG ++++ Q G + L G G Sbjct: 467 VDVDQDGETELLLIGAPLFYG--EQRGGRVFIYQRRQLGFEEVSE----LQGDPGYPLGR 520 Query: 369 FGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLA 428 FG ++ ++ DIN DG D+AVGAP E G VYI++ GL QP Q I G ++ L G+ Sbjct: 521 FGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQV-LSGIQ 579 Query: 429 TFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVH-KTLVPRPAVLDPALCTA 487 FG S+ G D++ + D+ VG+ S IV L +RPV+++V + P + C+ Sbjct: 580 WFGRSIHGVKDLEGDGLADVAVGAESQMIV-LSSRPVVDMVTLMSFSPAEIPVHEVECSY 638 Query: 488 TSC------VQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFHG 541 ++ V + +CF R L YTL+ D R R F G + Sbjct: 639 STSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRN 698 Query: 542 FFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQ 601 M C ++D + PI +S+N+SL + D PIL + Sbjct: 699 IAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSL 758 Query: 602 ALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTR 661 E E+ F+K CG D KCE+NL R +F + + L ++ L + ++++N Sbjct: 759 HSET-WEIPFEKNCGEDKKCEANL--RVSFSPARSRALRLTAFA----SLSVELSLSNLE 811 Query: 662 TSERSGEDAHEALLTLVVPPALLLSSV-------RPPGACQ--------ANETIFCELGN 706 EDA+ L L PP L V + P +C+ + + C + + Sbjct: 812 ------EDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSS 865 Query: 707 P-FKRNQRMELLIAFEVI 723 P FK + L + F + Sbjct: 866 PIFKAGHSVALQMMFNTL 883 Score = 32.3 bits (72), Expect = 2.4 Identities = 16/30 (53%), Positives = 23/30 (76%) Query: 992 LWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021 L+L +++ GLLLL LI ++L+K GFFKR Sbjct: 1090 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1119 >gi|52485853 integrin, alpha 11 precursor [Homo sapiens] Length = 1188 Score = 172 bits (435), Expect = 2e-42 Identities = 186/703 (26%), Positives = 301/703 (42%), Gaps = 89/703 (12%) Query: 183 EMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGN-------SYMIQRKEWDLS 235 E N N M Q G S ++ V GA GAY+W G +I +E L Sbjct: 353 EGTNKNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLK 412 Query: 236 EYSYKDPEDQGN--LYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLR 293 E+ PE+ N Y+GYT V S + + V GAPR H G V L + L Sbjct: 413 EF----PEELKNHGAYLGYT--VTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLT 466 Query: 294 RRQVLEGSQVGAYFGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVFMNQAGTS 352 Q + G Q+G+YFGS I D++ DG D LLVGAP YF E G +YV+ + Sbjct: 467 IHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRE-RGKVYVYELRQNLF 525 Query: 353 FPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSSKGLL 410 H + FG S+AS+ D+NQD + D+ VGAP E G +YI+H +L Sbjct: 526 VYNGTLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSIL 585 Query: 411 RQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVH 470 + P+Q I +L GL FG S+ GQ+D++E+ DL VG+L + V+L +RPV+ I + Sbjct: 586 KTPKQRITASELA-TGLQYFGCSIHGQLDLNEDGLIDLAVGALG-NAVILWSRPVVQI-N 642 Query: 471 KTLVPRPAVLD------PALCTATSCVQVELCFAYNQSAGNPNYR-RNITLAYTLEADRD 523 +L P+ ++ +C+ LCF A P+++ + + Y D Sbjct: 643 ASLHFEPSKINIFHRDCKRSGRDATCLAAFLCFTPIFLA--PHFQTTTVGIRYNATMDER 700 Query: 524 RRPPR--LRFAGSESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581 R PR L G S + C+++ ++D D ++P+ S+ YS Sbjct: 701 RYTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDT-ADYVKPVTFSVEYS------ 753 Query: 582 DRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRA----AFVSEQQQ 637 L D P+L+ V F C D C +L + A E Q Sbjct: 754 ------LEDPDHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQ 807 Query: 638 KLSRLQYSRDVRKLLLSINVT-----NTR-------TSERSGEDAHEALLTLVVPPALLL 685 ++ R + ++D LS + T +TR T E GE+A+ +L + L Sbjct: 808 RVLR-KPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQF 866 Query: 686 SS-VRPPGACQANETI---------FCELGNPFKR-NQRMELLIAFEVIGVTLHTRDLQV 734 +S ++ + + E + C + PF R ++ + FE ++ L++ Sbjct: 867 ASLIQKEDSDGSIECVNEERRLQKQVCNVSYPFFRAKAKVAFRLDFE-FSKSIFLHHLEI 925 Query: 735 QLQLSTSSH------QDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTV 788 +L + S+ +DN+ P+ + L+ ++ R S V S ++ Sbjct: 926 ELAAGSDSNERDSTKEDNVAPL------RFHLKYEADVLFTRSSSLSHYEVKPNSSLERY 979 Query: 789 EDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLL 831 + +G P F++ + GL + +++ + P +G LL Sbjct: 980 DGIGPPFSCIFRIQNL--GLFPIHGMMMKITIPIATRSGNRLL 1020 Score = 44.3 bits (103), Expect = 6e-04 Identities = 18/45 (40%), Positives = 31/45 (68%) Query: 981 ELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTR 1025 E+ ++ ++ +W+++ + GLLLL L++L LWK GFF+ AR R Sbjct: 1131 EISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRR 1175 >gi|116295258 integrin alpha 2 precursor [Homo sapiens] Length = 1181 Score = 171 bits (434), Expect = 3e-42 Identities = 217/896 (24%), Positives = 367/896 (40%), Gaps = 125/896 (13%) Query: 190 DYLETGMCQLGTSGGFT-QNTVYF-GAPGAYNWKGNSYMIQRKE-----WDLSEYSYKDP 242 D + M Q+G S ++ QN + GA GA+ W G ++Q+ + + Sbjct: 372 DNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGT--IVQKTSHGHLIFPKQAFDQILQ 429 Query: 243 EDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQ 302 + + Y+GY++ I ++ V GAPR + G + L S G++ Q G Q Sbjct: 430 DRNHSSYLGYSVAA---ISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQ 486 Query: 303 VGAYFGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLL 361 +G+YFGS + D++ D D LLVGAP Y ++ G +Y+F + G L Sbjct: 487 IGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGI---LGQHQFL 543 Query: 362 HGPSG---SAFGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYHSSSKGLLR--QPQ 414 GP G + FG ++A++ DIN DGF D+ VG+P E G VYIY + +G +R Q Sbjct: 544 EGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIY-NGHQGTIRTKYSQ 602 Query: 415 QVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINI-VHKTL 473 +++ + L FG SL G D++ + D+ +G+ +V L ++ + ++ + + Sbjct: 603 KILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG-QVVQLWSQSIADVAIEASF 661 Query: 474 VPRPAVLDPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAG 533 P L + + ++LCF+ N + I TL+AD Sbjct: 662 TPEKI----TLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNITLDAD----------GF 707 Query: 534 SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDA 593 S G F RC + +++ I I + + R + L + Sbjct: 708 SSRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGT 767 Query: 594 YPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLL 653 P L + F K+CG D C S+L + + Q++ S ++L Sbjct: 768 SPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQ--PFIVSNQNKRLTF 825 Query: 654 SINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPP-----GACQ---ANETIFCELG 705 S+ + N R E A+ + + L +S P CQ + +++ C++G Sbjct: 826 SVTLKNKR------ESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVG 879 Query: 706 NP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLS--------TSSHQDNLWPMILTLLV 756 P KR Q++ I F+ + ++LQ Q LS + DNL + + LL Sbjct: 880 YPALKREQQVTFTINFD-----FNLQNLQNQASLSFQALSESQEENKADNLVNLKIPLLY 934 Query: 757 DYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVL 816 D + + S + + G V S + + EDVG + +V G V + T+++ Sbjct: 935 DAEIHLTRSTNINFYEISSDGNV--PSIVHSFEDVGPKFIFSLKV-TTGSVPVSMATVII 991 Query: 817 GLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQ 876 + P L+Y T + G C INPL + Sbjct: 992 HI--PQYTKEKNPLMYLTGVQTDKAGDISCNAD---INPLKI------------------ 1028 Query: 877 LDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVTN--VTVKARVW 934 GQ V+ ++ + L C T A C + C + D + V V R+W Sbjct: 1029 -----GQTSSSVSF-KSENFRHTKELNCRT--ASCSNVTCWLKDVHMKGEYFVNVTTRIW 1080 Query: 935 NSTFIEDYRDFDRVRVNGWATLFLRTSIPTIN-MENKTTWFSVDIDSELVEELPAEIELW 993 N TF F V++ A + T P I +E+ T + I + + AE+ Sbjct: 1081 NGTFASS--TFQTVQLT--AAAEINTYNPEIYVIEDNTVTIPLMI---MKPDEKAEVPTG 1133 Query: 994 LVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQKAEMKSQPSETERLTD 1049 +++ ++ AG+LLL ++ +LWK GFFKR YE +M P E + T+ Sbjct: 1134 VIIGSIIAGILLLLALVAILWKLGFFKRK-----YE------KMTKNPDEIDETTE 1178 Score = 40.4 bits (93), Expect = 0.009 Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 15/173 (8%) Query: 4 GPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTE 63 GP R AP +L LAL C + A+N+ + +G FGY+V +Q Sbjct: 2 GPERTGAAPLPLLLVLALSQGILNCCL-AYNVGLPEAKIF-SGPSSEQFGYAV---QQFI 56 Query: 64 RQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGH--HIIED 121 + LL G+P P+ NR G VY CP+ CE++N+ + + + Sbjct: 57 NPKGNWLLVGSPWS-GFPE---NRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTN 112 Query: 122 MWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSS 174 M LG+ + G L C + Q +Q G C D +L +S Sbjct: 113 MSLGLILTRNMGTGGFLTCGPLWAQ----QCGNQYYTTGVCSDISPDFQLSAS 161 >gi|148728188 integrin, alpha E precursor [Homo sapiens] Length = 1179 Score = 170 bits (431), Expect = 6e-42 Identities = 162/593 (27%), Positives = 276/593 (46%), Gaps = 70/593 (11%) Query: 190 DYLETGMCQLGTSGGFT-QNTVYFGAPGAYNWKGNSYMIQRKE-----WDLSEYSYKDPE 243 D L + Q+G S + V GA GA++W G + + + + + + D E Sbjct: 395 DALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAE 454 Query: 244 DQGNLYIGYTMQVGSFILHPK-NITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQ 302 Y+GY + V LH +++ + GAPR++H GAVF L +E G + VLEG Q Sbjct: 455 AAQYSYLGYAVAV----LHKTCSLSYIAGAPRYKHHGAVFELQKE-GREASFLPVLEGEQ 509 Query: 303 VGAYFGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVF-MNQAGTSFPAHPSLL 360 +G+YFGS + D++ DG D LLV AP+Y EE G +YV+ +++ SF L Sbjct: 510 MGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEE--GRVYVYRLSEQDGSFSLARILS 567 Query: 361 LH-GPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--------LGKVYIYHSSSKGLLR 411 H G + + FG ++A++GD++QD D+A+GAP EG G VYIY+ GL Sbjct: 568 GHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSA 627 Query: 412 QPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK 471 P Q I + PGL FG S++G D+ + D+ VG+L +V R+RPV+ + Sbjct: 628 SPSQRIRASTVA-PGLQYFGMSMAGGFDISGDGLADITVGTLGQAVV-FRSRPVVRL-KV 684 Query: 472 TLVPRPAVLDPALCTATSCVQVELCFAYNQ-SAGNPNYRRNITLAYTLEADRDRRPPRLR 530 ++ P+ L V V LCF + + + + R L +TL+ D ++ RL+ Sbjct: 685 SMAFTPSALPIGF---NGVVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQ 741 Query: 531 FAGSESAV-FHGFFSMPEMRCQKLELLLMDN---LRDKLRPIIISMNYSL--PLRMPDRP 584 + S + +S C+ L L+ + D + ++Y L P D P Sbjct: 742 CSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDHP 801 Query: 585 RLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQY 644 + PIL++ ++ ++K C C + LQ+ A VS+Q+ + Sbjct: 802 Q---------PILDRYTEPFAIFQLPYEKACKNKLFCVAELQL-ATTVSQQELVVGL--- 848 Query: 645 SRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPGA----CQANETI 700 ++L L+IN+TN SGED++ + L P L L ++ P + C + + Sbjct: 849 ---TKELTLNINLTN------SGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPV 899 Query: 701 F------CELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNL 747 C +G+P + + + +++ R + + ++ S+ + +L Sbjct: 900 ASVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSL 952 Score = 42.7 bits (99), Expect = 0.002 Identities = 36/116 (31%), Positives = 61/116 (52%), Gaps = 9/116 (7%) Query: 926 NVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVD-IDSELVE 984 NVTV A + E +D +++ G + F ++ +N EN T +V + E Sbjct: 1065 NVTVAAEISWDHSEELLKDVTELQILGEIS-FNKSLYEGLNAENHRTKITVVFLKDEKYH 1123 Query: 985 ELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQKAEMKSQ 1040 LP +++ GLL+L +I+++L+KCGFFKR + E+ R KA++KS+ Sbjct: 1124 SLP------IIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLESIR-KAQLKSE 1172 >gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] Length = 1153 Score = 167 bits (422), Expect = 6e-41 Identities = 210/871 (24%), Positives = 364/871 (41%), Gaps = 123/871 (14%) Query: 193 ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGY 252 E M Q G S T N G+Y+W G ++ KE + D + Y+GY Sbjct: 347 EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406 Query: 253 TMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIA 312 + IL + ++V GAPR++H+G V + Q G V +G+Q+GAYFG+++ Sbjct: 407 AAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV-KGTQIGAYFGASLC 462 Query: 313 LADLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SA 368 D++++G DL L+GAP+Y+E+ GG + V G +L+G G Sbjct: 463 SVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGR 520 Query: 369 FGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYH-SSSKGLLRQPQQVIHGEKLGLP 425 FG ++ +GD+N D D+A+GAP E G VY++H +S G+ Q I G KL P Sbjct: 521 FGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLS-P 579 Query: 426 GLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV---PRPAVLDP 482 L FG SLSG D+ + DL VG+ H++LLR++PV+ + K ++ PR + Sbjct: 580 RLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLRV--KAIMEFNPREVARNV 636 Query: 483 ALCT-----ATSCVQVELCFAYNQSAGNPNYRRNI--TLAYTLEADRDRRPPRLRFAGSE 535 C +V +C +S + I + Y L D R R F ++ Sbjct: 637 FECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETK 696 Query: 536 SAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAY 594 ++ + C+ L+L L + + D + PI++ +N+SL + P LR Sbjct: 697 NSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL-VGTPLSAFGNLR----- 750 Query: 595 PILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLS 654 P+L + F+K CG DN C+ +L + +F+S + R+ ++ Sbjct: 751 PVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG------GPREFNVT 804 Query: 655 INVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPG----------ACQ--------- 695 + V N GED++ +T P L V AC+ Sbjct: 805 VTVRN------DGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 858 Query: 696 ANETIFCELGNP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH--QDNLWPMIL 752 A ++ C + +P F N + I F+V L ++ +++ ++ + N L Sbjct: 859 ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQL 918 Query: 753 TLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLG 812 L V Y + + + +H + + + E+ +++++QV +G+ + + Sbjct: 919 ELPVKYAVY--MVVTSHGVSTKY-------LNFTASENTSRVMQHQYQVSNLGQRSLPIS 969 Query: 813 TLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQR 872 L++ + ++ W RP L+ T PS Sbjct: 970 -----------------LVFLVPVRLNQTVIWD-RPQVTFSENLSSTCHTKERLPSHSD- 1010 Query: 873 RRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVT--NVTVK 930 LA +KA V+ C+ A C ++C IP + N T+K Sbjct: 1011 ----------------FLAELRKA---PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLK 1049 Query: 931 ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990 + +I+ + + + A + S+ T+ + + + +++ VE Sbjct: 1050 GNLSFDWYIK--TSHNHLLIVSTAEILFNDSVFTL-LPGQGAFVRSQTETK-VEPFEVPN 1105 Query: 991 ELWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021 L L++ + GLLLL LI L+K GFFKR Sbjct: 1106 PLPLIVGSSVGGLLLLALITAALYKLGFFKR 1136 >gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] Length = 1152 Score = 164 bits (414), Expect = 5e-40 Identities = 210/871 (24%), Positives = 365/871 (41%), Gaps = 124/871 (14%) Query: 193 ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGY 252 E M Q G S T N G+Y+W G ++ KE + D + Y+GY Sbjct: 347 EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406 Query: 253 TMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIA 312 + IL + ++V GAPR++H+G V + Q G V +G+Q+GAYFG+++ Sbjct: 407 AAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV-KGTQIGAYFGASLC 462 Query: 313 LADLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SA 368 D++++G DL L+GAP+Y+E+ GG + V G + +L+G G Sbjct: 463 SVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRA-RWQCDAVLYGEQGQPWGR 519 Query: 369 FGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYH-SSSKGLLRQPQQVIHGEKLGLP 425 FG ++ +GD+N D D+A+GAP E G VY++H +S G+ Q I G KL P Sbjct: 520 FGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLS-P 578 Query: 426 GLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV---PRPAVLDP 482 L FG SLSG D+ + DL VG+ H++LLR++PV+ + K ++ PR + Sbjct: 579 RLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLRV--KAIMEFNPREVARNV 635 Query: 483 ALCT-----ATSCVQVELCFAYNQSAGNPNYRRNI--TLAYTLEADRDRRPPRLRFAGSE 535 C +V +C +S + I + Y L D R R F ++ Sbjct: 636 FECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETK 695 Query: 536 SAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAY 594 ++ + C+ L+L L + + D + PI++ +N+SL + P LR Sbjct: 696 NSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL-VGTPLSAFGNLR----- 749 Query: 595 PILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLS 654 P+L + F+K CG DN C+ +L + +F+S + R+ ++ Sbjct: 750 PVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG------GPREFNVT 803 Query: 655 INVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPG----------ACQ--------- 695 + V N GED++ +T P L V AC+ Sbjct: 804 VTVRN------DGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 857 Query: 696 ANETIFCELGNP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH--QDNLWPMIL 752 A ++ C + +P F N + I F+V L ++ +++ ++ + N L Sbjct: 858 ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQL 917 Query: 753 TLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLG 812 L V Y + + + +H + + + E+ +++++QV +G+ + + Sbjct: 918 ELPVKYAVY--MVVTSHGVSTKY-------LNFTASENTSRVMQHQYQVSNLGQRSLPIS 968 Query: 813 TLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQR 872 L++ + ++ W RP L+ T PS Sbjct: 969 -----------------LVFLVPVRLNQTVIWD-RPQVTFSENLSSTCHTKERLPSHSD- 1009 Query: 873 RRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVT--NVTVK 930 LA +KA V+ C+ A C ++C IP + N T+K Sbjct: 1010 ----------------FLAELRKA---PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLK 1048 Query: 931 ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990 + +I+ + + + A + S+ T+ + + + +++ VE Sbjct: 1049 GNLSFDWYIK--TSHNHLLIVSTAEILFNDSVFTL-LPGQGAFVRSQTETK-VEPFEVPN 1104 Query: 991 ELWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021 L L++ + GLLLL LI L+K GFFKR Sbjct: 1105 PLPLIVGSSVGGLLLLALITAALYKLGFFKR 1135 >gi|62548866 integrin, alpha D precursor [Homo sapiens] Length = 1161 Score = 156 bits (395), Expect = 8e-38 Identities = 139/516 (26%), Positives = 244/516 (47%), Gaps = 69/516 (13%) Query: 196 MCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGYTMQ 255 M Q G S T + ++ GA G+++W G +++ ++ D + Y+GY+ + Sbjct: 350 MSQEGFSTALTMDGLFLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTE 409 Query: 256 VGSFILHPKNI-TIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALA 314 + + K + +V GAPR++H G + +Q R++ + G+Q+G+YFG+++ Sbjct: 410 LALW----KGVQNLVLGAPRYQHTGKAVIFTQ-VSRQWRKKAEVTGTQIGSYFGASLCSV 464 Query: 315 DLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SAFG 370 D+++DG DL L+GAP+Y+E+ GG + V G +L G G FG Sbjct: 465 DVDSDGSTDLILIGAPHYYEQTR--GGQVSVCPLPRG-RVQWQCDAVLRGEQGHPWGRFG 521 Query: 371 LSVASIGDINQDGFQDIAVGAP--FEGLGKVYIYHSSSK-GLLRQPQQVIHGEKLGLPGL 427 ++ +GD+N+D D+A+GAP E G VY++H +S+ G+ Q I +L P L Sbjct: 522 AALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLS-PRL 580 Query: 428 ATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINI--------------VHKTL 473 FG +LSG D+ ++ DL VG+ ++LLR+ PV+ + V++ Sbjct: 581 QYFGQALSGGQDLTQDGLMDLAVGA-RGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCW 639 Query: 474 VPRPAVLDPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAG 533 +P+ L+ T +C +S+ + ++ + L D R R F Sbjct: 640 EEKPSALEAGDAT--------VCLTIQKSSLDQLGDIQSSVRFDLALDPGRLTSRAIFNE 691 Query: 534 SESAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSL---PLRMPD--RPRLG 587 +++ ++ + C+ L+LLL D + D + PII+ +N+SL P+ P RP L Sbjct: 692 TKNPTLTRRKTLGLGIHCETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQNLRPVLA 751 Query: 588 LRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRD 647 + S D + + F+K CG D CE +L + +F S LQ Sbjct: 752 VGSQDLFT-----------ASLPFEKNCGQDGLCEGDLGVTLSF--------SGLQTLTV 792 Query: 648 VRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL 683 L L++ V T +GED++ +++L P L Sbjct: 793 GSSLELNVIV----TVWNAGEDSYGTVVSLYYPAGL 824 >gi|34452173 integrin alpha X precursor [Homo sapiens] Length = 1163 Score = 147 bits (370), Expect = 7e-35 Identities = 124/465 (26%), Positives = 221/465 (47%), Gaps = 39/465 (8%) Query: 187 SNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQG 246 +++ E M Q G S FT + GA G++ W G +++ ++ D Sbjct: 342 TSSSSFELEMAQEGFSAVFTPDGPVLGAVGSFTWSGGAFLYPPNMSPTFINMSQENVDMR 401 Query: 247 NLYIGYTMQVGSFILHPKNI-TIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGA 305 + Y+GY+ ++ + K + ++V GAPR++H G + +Q R + + G+Q+G+ Sbjct: 402 DSYLGYSTELALW----KGVQSLVLGAPRYQHTGKAVIFTQ-VSRQWRMKAEVTGTQIGS 456 Query: 306 YFGSAIALADLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGP 364 YFG+++ D+++DG DL L+GAP+Y+E+ GG + V G +L+G Sbjct: 457 YFGASLCSVDVDSDGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGWR-RWWCDAVLYGE 513 Query: 365 SG---SAFGLSVASIGDINQDGFQDIAVGAP--FEGLGKVYIYHSSSKGLLRQPQQVIHG 419 G FG ++ +GD+N D D+ +GAP E G VY++H G+L H Sbjct: 514 QGHPWGRFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFH----GVLGPSISPSHS 569 Query: 420 EKLGLPGLAT----FGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINI-VHKTLV 474 +++ L++ FG +LSG D+ ++ DL VG+ ++LLR RPV+ + V + Sbjct: 570 QRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGA-RGQVLLLRTRPVLWVGVSMQFI 628 Query: 475 PRPAVLDPALC-----TATSCVQVELCFAYNQSAGNPNYRRNITLAYTLE--ADRDRRPP 527 P C + + VQ +C ++ + N R++ + TL+ D R P Sbjct: 629 PAEIPRSAFECREQVVSEQTLVQSNICLYIDKRSKNLLGSRDLQSSVTLDLALDPGRLSP 688 Query: 528 RLRFAGSESAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRL 586 R F +++ + + C+ LLL + D + PI + +N++L +P L Sbjct: 689 RATFQETKNRSLSRVRVLGLKAHCENFNLLLPSCVEDSVTPITLRLNFTL----VGKPLL 744 Query: 587 GLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAF 631 R+L P+L + F+K CG D+ C+ NL + +F Sbjct: 745 AFRNL--RPMLAADAQRYFTASLPFEKNCGADHICQDNLGISFSF 787 Score = 34.7 bits (78), Expect = 0.48 Identities = 22/47 (46%), Positives = 26/47 (55%), Gaps = 5/47 (10%) Query: 1002 GLLLLGLIILLLWKCGFFKRARTRALYEAKRQKA-----EMKSQPSE 1043 GLLLL LI +L+K GFFKR + EA Q A + S PSE Sbjct: 1116 GLLLLALITAVLYKVGFFKRQYKEMMEEANGQIAPENGTQTPSPPSE 1162 >gi|29171717 glycosylphosphatidylinositol specific phospholipase D1 isoform 1 precursor [Homo sapiens] Length = 840 Score = 63.2 bits (152), Expect = 1e-09 Identities = 55/195 (28%), Positives = 81/195 (41%), Gaps = 18/195 (9%) Query: 273 PRHRHMGAVFLLSQEAGG--------DLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDL 324 P H H+G V+L+ G D ++LEG Q FGSA+A+ D N DG DL Sbjct: 408 PGHIHIGRVYLIYGNDLGLPPVDLDLDKEAHRILEGFQPSGRFGSALAVLDFNVDGVPDL 467 Query: 325 LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSGSAFGLSVASIGDINQDGF 384 VGAP + GA+YV+ + P++ + D+N D Sbjct: 468 AVGAPSVGSEQLTYKGAVYVYFGSKQGGMSSSPNITISCQDIYCNLGWTLLAADVNGDSE 527 Query: 385 QDIAVGAPF-------EGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQ 437 D+ +G+PF +G+ + S + + + G + FGYSL G Sbjct: 528 PDLVIGSPFAPGGGKQKGIVAAFYSGPSLSDKEKLNVEAANWTVRGEEDFSWFGYSLHG- 586 Query: 438 MDVDENFYPDLLVGS 452 + VD LLVGS Sbjct: 587 VTVDNRTL--LLVGS 599 Score = 62.0 bits (149), Expect = 3e-09 Identities = 82/293 (27%), Positives = 126/293 (43%), Gaps = 42/293 (14%) Query: 186 NSNTDYLETGMCQLGTSG-GFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPED 244 ++N +L + M + GTS +N ++ G N S M + S + D Sbjct: 258 STNIYHLTSFMLENGTSDCNLPENPLFIACGGQQNHTQGSKMQKNDFHRNLTTSLTESVD 317 Query: 245 QGNLYI--GYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQ 302 + Y G V S+ P +++ + A R++ +F+ G L ++ V S Sbjct: 318 RNINYTERGVFFSVNSWT--PDSMSFIYKA-LERNIRTMFI----GGSQLSQKHV--SSP 368 Query: 303 VGAYF--------GSAIALADLNNDGWQDLLVGAPYYFERKE-EVGGAIYVFMNQAG--- 350 + +YF G A+ ADLN DG DL+VGAP Y +G ++ N G Sbjct: 369 LASYFLSFPYARLGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPP 428 Query: 351 ----TSFPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG------LGKVY 400 AH L PSG FG ++A + D N DG D+AVGAP G G VY Sbjct: 429 VDLDLDKEAHRILEGFQPSG-RFGSALAVL-DFNVDGVPDLAVGAPSVGSEQLTYKGAVY 486 Query: 401 IYHSSSK-GLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGS 452 +Y S + G+ P I + + G++L DV+ + PDL++GS Sbjct: 487 VYFGSKQGGMSSSPNITISCQDI----YCNLGWTLLA-ADVNGDSEPDLVIGS 534 >gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] Length = 397 Score = 35.0 bits (79), Expect = 0.37 Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 12/106 (11%) Query: 347 NQAGTSFPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSS 406 + A SFP PSL GP+ +G S+G+ Q A+G P LG + H Sbjct: 251 SDAEVSFPDEPSLAEMGPANGLYG----SLGEPTQ------ALGRPSGALGNFSLEHGGL 300 Query: 407 KGLLRQPQQVIHGEKLGLPGLATFGYSLSG-QMDVDENFYPDLLVG 451 G Q +++ G G+P SL G Q + YPD +G Sbjct: 301 AG-PEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLG 345 >gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] Length = 402 Score = 35.0 bits (79), Expect = 0.37 Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 12/106 (11%) Query: 347 NQAGTSFPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSS 406 + A SFP PSL GP+ +G S+G+ Q A+G P LG + H Sbjct: 256 SDAEVSFPDEPSLAEMGPANGLYG----SLGEPTQ------ALGRPSGALGNFSLEHGGL 305 Query: 407 KGLLRQPQQVIHGEKLGLPGLATFGYSLSG-QMDVDENFYPDLLVG 451 G Q +++ G G+P SL G Q + YPD +G Sbjct: 306 AG-PEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLG 350 >gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo sapiens] Length = 462 Score = 34.7 bits (78), Expect = 0.48 Identities = 22/47 (46%), Positives = 26/47 (55%), Gaps = 5/47 (10%) Query: 1002 GLLLLGLIILLLWKCGFFKRARTRALYEAKRQKA-----EMKSQPSE 1043 GLLLL LI +L+K GFFKR + EA Q A + S PSE Sbjct: 415 GLLLLALITAVLYKVGFFKRQYKEMMEEANGQIAPENGTQTPSPPSE 461 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.137 0.419 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 43,925,595 Number of Sequences: 37866 Number of extensions: 2147182 Number of successful extensions: 5246 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 4869 Number of HSP's gapped (non-prelim): 67 length of query: 1051 length of database: 18,247,518 effective HSP length: 113 effective length of query: 938 effective length of database: 13,968,660 effective search space: 13102603080 effective search space used: 13102603080 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.