Guide to the Human Genome
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Search of human proteins with 4504747

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
         (1051 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]       2140   0.0  
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]       2083   0.0  
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [...   650   0.0  
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [...   632   0.0  
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]      628   e-179
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]      619   e-177
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]                522   e-148
gi|49170034 integrin, alpha 8 [Homo sapiens]                          289   8e-78
gi|52485941 integrin, alpha 9 precursor [Homo sapiens]                275   1e-73
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]        270   5e-72
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]            269   1e-71
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]                260   4e-69
gi|56237029 integrin alpha 5 precursor [Homo sapiens]                 258   2e-68
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]      248   2e-65
gi|67191027 integrin alpha 4 precursor [Homo sapiens]                 245   2e-64
gi|31657142 integrin, alpha 1 precursor [Homo sapiens]                233   9e-61
gi|38569398 integrin, alpha 10 precursor [Homo sapiens]               179   2e-44
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]      176   1e-43
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]      173   7e-43
gi|52485853 integrin, alpha 11 precursor [Homo sapiens]               172   2e-42
gi|116295258 integrin alpha 2 precursor [Homo sapiens]                171   3e-42
gi|148728188 integrin, alpha E precursor [Homo sapiens]               170   6e-42
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]      167   6e-41
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]       164   5e-40
gi|62548866 integrin, alpha D precursor [Homo sapiens]                156   8e-38
gi|34452173 integrin alpha X precursor [Homo sapiens]                 147   7e-35
gi|29171717 glycosylphosphatidylinositol specific phospholipase ...    63   1e-09
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]            35   0.37 
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]             35   0.37 
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ...    35   0.48 

>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
          Length = 1051

 Score = 2140 bits (5545), Expect = 0.0
 Identities = 1051/1051 (100%), Positives = 1051/1051 (100%)

Query: 1    MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR 60
            MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR
Sbjct: 1    MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR 60

Query: 61   QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIE 120
            QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIE
Sbjct: 61   QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIE 120

Query: 121  DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTY 180
            DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTY
Sbjct: 121  DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTY 180

Query: 181  HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK 240
            HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK
Sbjct: 181  HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK 240

Query: 241  DPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEG 300
            DPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEG
Sbjct: 241  DPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEG 300

Query: 301  SQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLL 360
            SQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLL
Sbjct: 301  SQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLL 360

Query: 361  LHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGE 420
            LHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGE
Sbjct: 361  LHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGE 420

Query: 421  KLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVL 480
            KLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVL
Sbjct: 421  KLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVL 480

Query: 481  DPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFH 540
            DPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFH
Sbjct: 481  DPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFH 540

Query: 541  GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA 600
            GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA
Sbjct: 541  GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA 600

Query: 601  QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT 660
            QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT
Sbjct: 601  QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT 660

Query: 661  RTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAF 720
            RTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAF
Sbjct: 661  RTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAF 720

Query: 721  EVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM 780
            EVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM
Sbjct: 721  EVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM 780

Query: 781  GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG 840
            GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG
Sbjct: 781  GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG 840

Query: 841  NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSET 900
            NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSET
Sbjct: 841  NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSET 900

Query: 901  VLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRT 960
            VLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRT
Sbjct: 901  VLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRT 960

Query: 961  SIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFK 1020
            SIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFK
Sbjct: 961  SIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFK 1020

Query: 1021 RARTRALYEAKRQKAEMKSQPSETERLTDDY 1051
            RARTRALYEAKRQKAEMKSQPSETERLTDDY
Sbjct: 1021 RARTRALYEAKRQKAEMKSQPSETERLTDDY 1051


>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
          Length = 1066

 Score = 2083 bits (5397), Expect = 0.0
 Identities = 1026/1044 (98%), Positives = 1029/1044 (98%), Gaps = 3/1044 (0%)

Query: 1    MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR 60
            MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR
Sbjct: 1    MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR 60

Query: 61   QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIE 120
            QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIE
Sbjct: 61   QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIE 120

Query: 121  DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTY 180
            DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTY
Sbjct: 121  DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTY 180

Query: 181  HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK 240
            HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK
Sbjct: 181  HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK 240

Query: 241  DPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEG 300
            DPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEG
Sbjct: 241  DPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEG 300

Query: 301  SQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLL 360
            SQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLL
Sbjct: 301  SQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLL 360

Query: 361  LHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGE 420
            LHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGE
Sbjct: 361  LHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGE 420

Query: 421  KLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVL 480
            KLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVL
Sbjct: 421  KLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVL 480

Query: 481  DPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFH 540
            DPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFH
Sbjct: 481  DPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFH 540

Query: 541  GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA 600
            GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA
Sbjct: 541  GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA 600

Query: 601  QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT 660
            QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT
Sbjct: 601  QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT 660

Query: 661  RTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAF 720
            RTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAF
Sbjct: 661  RTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAF 720

Query: 721  EVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM 780
            EVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM
Sbjct: 721  EVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM 780

Query: 781  GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG 840
            GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG
Sbjct: 781  GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG 840

Query: 841  NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSET 900
            NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSET
Sbjct: 841  NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSET 900

Query: 901  VLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRT 960
            VLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRT
Sbjct: 901  VLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRT 960

Query: 961  SIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFK 1020
            SIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKC FFK
Sbjct: 961  SIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCDFFK 1020

Query: 1021 RARTRAL---YEAKRQKAEMKSQP 1041
            R R   +   Y A R + E +  P
Sbjct: 1021 RTRYYQIMPKYHAVRIREEERYPP 1044


>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
            sapiens]
          Length = 1073

 Score =  650 bits (1677), Expect = 0.0
 Identities = 416/1094 (38%), Positives = 600/1094 (54%), Gaps = 87/1094 (7%)

Query: 16   LCALALMVAAGGCVVSAFNLDTRF-LVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGA 74
            LC L L       + +AFNLDTR   V+++ G+PGSLFG+S+A+H Q + + + LLL GA
Sbjct: 7    LCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGA 66

Query: 75   PRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPA 134
            PR  A+P    NRTG +Y C +TA +  C R+      DP     ED W+GVTV SQGP 
Sbjct: 67   PRAEALPLQRANRTGGLYSCDITA-RGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPG 125

Query: 135  GRVLVCAHRYTQVLWSGSEDQRRMV-GKCYVRGNDLELDSSDDWQTYHNEMCNSNT-DYL 192
            G+V+ CAHRY +     ++ + R + G+CYV   +L ++  DD        C+     + 
Sbjct: 126  GKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIE--DDMDGGDWSFCDGRLRGHE 183

Query: 193  ETGMCQLGTSGGFTQNTVY--FGAPGAYNWKGNSYMIQRKEWDLSEYSYKD-PEDQG--- 246
            + G CQ G +  FT++  Y  FGAPG YNWKG   + Q+         ++D P + G   
Sbjct: 184  KFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGET 243

Query: 247  -----------NLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEA-GGDLRR 294
                       N Y+G+++  G  I+    IT V+GAPR  H GAV LL ++     L  
Sbjct: 244  EHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLP 303

Query: 295  RQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFP 354
              + +G  + + FG  +A+ DLN DGWQD+++GAP YF+R  EVGGA+YV+MNQ G    
Sbjct: 304  EHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNN 363

Query: 355  AHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQ 414
              P + L+G   S FG++V +IGDINQDG+ DIAVGAP++ LGKV+IYH S+ G+  +P 
Sbjct: 364  VKP-IRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPT 422

Query: 415  QVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV 474
            QV+ G          FGYS++G MD+D N YPD+ VGSLSD + + R+RPVINI  KT+ 
Sbjct: 423  QVLKGIS------PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINI-QKTIT 475

Query: 475  PRPAVLD---PALCTATS--CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRL 529
              P  +D      C A S  C+QV+ CF Y  +A    Y  +I++  TLEA+++RR   L
Sbjct: 476  VTPNRIDLRQKTACGAPSGICLQVKSCFEY--TANPAGYNPSISIVGTLEAEKERRKSGL 533

Query: 530  ------RFAGSESAVFHGFFSMPEMR--CQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581
                  R  GSE           + +  C +  L L DN+RDKLRPI I+   S+ ++ P
Sbjct: 534  SSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITA--SVEIQEP 591

Query: 582  DRPRLGLRSLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQMRAAFVSEQ--QQK 638
               R      +  PILN  +    H +V F KE CG DN C SNL++   F + +  Q K
Sbjct: 592  SSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDK 651

Query: 639  LSRLQYSRDVRKLLLS--------INVTNTRTSERS----GEDAHEALLTLVVPPALLLS 686
             S L   + V +L+L         I VTN+ ++ R+    G+DAHEA L    P  L  S
Sbjct: 652  FSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYS 711

Query: 687  SVRPPGA-------CQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQL 736
            + R   A       C AN+      CELGNPFKRN  +   +      VT  T DL + L
Sbjct: 712  AYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINL 771

Query: 737  QLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLK 796
            +L T+S+QDNL P+     V   L  S+S V    Q +FGGTV+GE  MK+ ++VGS ++
Sbjct: 772  KLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIE 831

Query: 797  YEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPL 856
            YEF+V  +G+ L  LGT  L ++WP E+SNGKWLLY  ++   G     C P  + IN L
Sbjct: 832  YEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKE-INSL 890

Query: 857  NLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLEC 916
            NLT        S   R++R++           +L A +K ++   L C+    +CV + C
Sbjct: 891  NLT-------ESHNSRKKREITEKQIDDNRKFSLFAERKYQT---LNCSV-NVNCVNIRC 939

Query: 917  PIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSV 976
            P+       ++ +++R+WNSTF+E+Y   + + +   A + +  +   I + N  T   V
Sbjct: 940  PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRV 999

Query: 977  DIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQKAE 1036
             +         + +  W++LVA+ AG+L+L L++ +LWKCGFFKR + +  Y+A   KAE
Sbjct: 1000 TVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNK-KDHYDATYHKAE 1058

Query: 1037 MKSQPSETERLTDD 1050
            + +QPS+ ERLT D
Sbjct: 1059 IHAQPSDKERLTSD 1072


>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
            sapiens]
          Length = 1091

 Score =  632 bits (1631), Expect = 0.0
 Identities = 404/1067 (37%), Positives = 583/1067 (54%), Gaps = 86/1067 (8%)

Query: 16   LCALALMVAAGGCVVSAFNLDTRF-LVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGA 74
            LC L L       + +AFNLDTR   V+++ G+PGSLFG+S+A+H Q + + + LLL GA
Sbjct: 7    LCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGA 66

Query: 75   PRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPA 134
            PR  A+P    NRTG +Y C +TA +  C R+      DP     ED W+GVTV SQGP 
Sbjct: 67   PRAEALPLQRANRTGGLYSCDITA-RGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPG 125

Query: 135  GRVLVCAHRYTQVLWSGSEDQRRMV-GKCYVRGNDLELDSSDDWQTYHNEMCNSNT-DYL 192
            G+V+ CAHRY +     ++ + R + G+CYV   +L ++  DD        C+     + 
Sbjct: 126  GKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIE--DDMDGGDWSFCDGRLRGHE 183

Query: 193  ETGMCQLGTSGGFTQNTVY--FGAPGAYNWKGNSYMIQRKEWDLSEYSYKD-PEDQG--- 246
            + G CQ G +  FT++  Y  FGAPG YNWKG   + Q+         ++D P + G   
Sbjct: 184  KFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGET 243

Query: 247  -----------NLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEA-GGDLRR 294
                       N Y+G+++  G  I+    IT V+GAPR  H GAV LL ++     L  
Sbjct: 244  EHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLP 303

Query: 295  RQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFP 354
              + +G  + + FG  +A+ DLN DGWQD+++GAP YF+R  EVGGA+YV+MNQ G    
Sbjct: 304  EHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNN 363

Query: 355  AHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQ 414
              P + L+G   S FG++V +IGDINQDG+ DIAVGAP++ LGKV+IYH S+ G+  +P 
Sbjct: 364  VKP-IRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPT 422

Query: 415  QVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV 474
            QV+ G          FGYS++G MD+D N YPD+ VGSLSD + + R+RPVINI  KT+ 
Sbjct: 423  QVLKGIS------PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINI-QKTIT 475

Query: 475  PRPAVLD---PALCTATS--CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRL 529
              P  +D      C A S  C+QV+ CF Y  +A    Y  +I++  TLEA+++RR   L
Sbjct: 476  VTPNRIDLRQKTACGAPSGICLQVKSCFEY--TANPAGYNPSISIVGTLEAEKERRKSGL 533

Query: 530  ------RFAGSESAVFHGFFSMPEMR--CQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581
                  R  GSE           + +  C +  L L DN+RDKLRPI I+   S+ ++ P
Sbjct: 534  SSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITA--SVEIQEP 591

Query: 582  DRPRLGLRSLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQMRAAFVSEQ--QQK 638
               R      +  PILN  +    H +V F KE CG DN C SNL++   F + +  Q K
Sbjct: 592  SSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDK 651

Query: 639  LSRLQYSRDVRKLLLS--------INVTNTRTSERS----GEDAHEALLTLVVPPALLLS 686
             S L   + V +L+L         I VTN+ ++ R+    G+DAHEA L    P  L  S
Sbjct: 652  FSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYS 711

Query: 687  SVRPPGA-------CQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQL 736
            + R   A       C AN+      CELGNPFKRN  +   +      VT  T DL + L
Sbjct: 712  AYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINL 771

Query: 737  QLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLK 796
            +L T+S+QDNL P+     V   L  S+S V    Q +FGGTV+GE  MK+ ++VGS ++
Sbjct: 772  KLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIE 831

Query: 797  YEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPL 856
            YEF+V  +G+ L  LGT  L ++WP E+SNGKWLLY  ++   G     C P  + IN L
Sbjct: 832  YEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKE-INSL 890

Query: 857  NLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLEC 916
            NLT        S   R++R++           +L A +K ++   L C+    +CV + C
Sbjct: 891  NLT-------ESHNSRKKREITEKQIDDNRKFSLFAERKYQT---LNCSV-NVNCVNIRC 939

Query: 917  PIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSV 976
            P+       ++ +++R+WNSTF+E+Y   + + +   A + +  +   I + N  T   V
Sbjct: 940  PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRV 999

Query: 977  DIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023
             +         + +  W++LVA+ AG+L+L L++ +LWKCGFFKR+R
Sbjct: 1000 TVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRSR 1046


>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
          Length = 1137

 Score =  628 bits (1619), Expect = e-179
 Identities = 403/1068 (37%), Positives = 595/1068 (55%), Gaps = 107/1068 (10%)

Query: 32   AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91
            AFNLD    + KE G PGSLFG+SVALHRQ + + +  LL GAP+ LA+P    NRTG +
Sbjct: 33   AFNLDVMGALRKE-GEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGL 91

Query: 92   YLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPAGRVLVCAHRY------T 145
            + CPL+  + DC R++I    D      E+ WLGV+V SQGP G+++ CAHRY       
Sbjct: 92   FACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVD 151

Query: 146  QVLWSGSEDQRRMVGKCYVRGNDL----ELDSSDDWQTYHNEMCNSNTD-YLETGMCQLG 200
            Q+L     + R M+G+C+V   DL    ELD   +W     + C      + + G CQ G
Sbjct: 152  QIL-----ETRDMIGRCFVLSQDLAIRDELDGG-EW-----KFCEGRPQGHEQFGFCQQG 200

Query: 201  TSGGFTQNTVY--FGAPGAYNWKGNSYMIQRKEWDLSEYSYK--DPEDQ---------GN 247
            T+  F+ ++ Y  FGAPG YNWKG  ++      D  +  YK  DP D+          N
Sbjct: 201  TAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALN 260

Query: 248  LYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYF 307
             Y+G+++  G  ++  + ++ V GAPR  H GAV +L +++   L    +L G ++ + F
Sbjct: 261  SYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGF 320

Query: 308  GSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSGS 367
            G ++A+ADLN+DGW DL+VGAPY+FER+EE+GGA+YV++NQ G      P L L G   S
Sbjct: 321  GYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISP-LRLCGSPDS 379

Query: 368  AFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGL 427
             FG+S+A +GD+NQDGF DIAVGAPF+G GKV+IYH SS G++ +P QV+ GE +   G+
Sbjct: 380  MFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV---GI 436

Query: 428  ATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLVPRPAVLDPALCT 486
             +FGYSLSG +D+D N YPDLLVGSL+D  VL RARP++++ H+ ++ PR   L+   C 
Sbjct: 437  KSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCA 496

Query: 487  A--TSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR----PPRLRFAG------- 533
               + CV + +CF+Y   A   +Y   + L Y L+AD DRR     PR+ F         
Sbjct: 497  GGHSVCVDLRVCFSY--IAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPK 554

Query: 534  SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDA 593
             +++         +  C      L +N++DKLR I+++++YSL      R   G      
Sbjct: 555  HQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPV 614

Query: 594  YPILNQAQALENHTEVQFQKE-CGPDNKCESNLQM-RAAFVSE-QQQKLSRLQYSRDVRK 650
             PILN  Q      E+ F K+ CG D  C+SNLQ+ RA F +     +   L    D   
Sbjct: 615  APILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT 674

Query: 651  LL----------LSINVTNTRTS----ERSGEDAHEALLTLVVPPALLLSSVR-----PP 691
             L          L + VTN  +     +  G+DAHEA L +++P +L  S VR       
Sbjct: 675  ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 734

Query: 692  GACQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLW 748
              C +NE    + CELGNP KR  ++   +     G+++ T +L+V+L L+T S Q+ L 
Sbjct: 735  PLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQE-LH 793

Query: 749  PMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGL 808
            P+     V   L  S++ +    Q FF G V GE  M++  DVGS +KYE  V   G+ L
Sbjct: 794  PVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSL 853

Query: 809  VGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWP-----CRPPGDLINPLNLTLSDP 863
              LG+  L + WP+E++NGKWLLYP ++ + G G  P     C P  ++++ L++     
Sbjct: 854  RTLGSAFLNIMWPHEIANGKWLLYPMQVELEG-GQGPGQKGLCSPRPNILH-LDV----- 906

Query: 864  GDRPSSPQRRRRQLDPGGGQGP-----PPVT---LAAAKKAKSETVLTCATGRAHCVWLE 915
                 S  RRRR+L+P   Q P     P ++   +++A+K K+ T L CA G A+CV   
Sbjct: 907  ----DSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT-LDCARGTANCVVFS 961

Query: 916  CPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFS 975
            CP+        + V  R+WNSTF+E+Y     + V   A + +++SI  + + + +T   
Sbjct: 962  CPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIP 1021

Query: 976  VDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023
            V +  + +  +   +  W++L+AV AGLL+L L++LLLWK GFFKRA+
Sbjct: 1022 VMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1069


>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 1141

 Score =  619 bits (1597), Expect = e-177
 Identities = 399/1072 (37%), Positives = 592/1072 (55%), Gaps = 111/1072 (10%)

Query: 32   AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91
            AFNLD    + KE G PGSLFG+SVALHRQ + + +  LL GAP+ LA+P    NRTG +
Sbjct: 33   AFNLDVMGALRKE-GEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGL 91

Query: 92   YLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPAGRVLVCAHRY------T 145
            + CPL+  + DC R++I    D      E+ WLGV+V SQGP G+++ CAHRY       
Sbjct: 92   FACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVD 151

Query: 146  QVLWSGSEDQRRMVGKCYVRGNDL----ELDSSDDWQTYHNEMCNSNTD-YLETGMCQLG 200
            Q+L     + R M+G+C+V   DL    ELD   +W     + C      + + G CQ G
Sbjct: 152  QIL-----ETRDMIGRCFVLSQDLAIRDELDGG-EW-----KFCEGRPQGHEQFGFCQQG 200

Query: 201  TSGGFTQNTVY--FGAPGAYNWKGNSYM------------IQRKEWDLSEYSYKDPE--- 243
            T+  F+ ++ Y  FGAPG YNWKG + +            +    ++      +DP    
Sbjct: 201  TAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIP 260

Query: 244  DQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQV 303
               N Y G+++  G  ++  + ++ V GAPR  H GAV +L +++   L    +L G ++
Sbjct: 261  VPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERL 320

Query: 304  GAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHG 363
             + FG ++A+ADLN+DGW DL+VGAPY+FER+EE+GGA+YV++NQ G      P L L G
Sbjct: 321  TSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISP-LRLCG 379

Query: 364  PSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLG 423
               S FG+S+A +GD+NQDGF DIAVGAPF+G GKV+IYH SS G++ +P QV+ GE + 
Sbjct: 380  SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV- 438

Query: 424  LPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLVPRPAVLDP 482
              G+ +FGYSLSG +D+D N YPDLLVGSL+D  VL RARP++++ H+ ++ PR   L+ 
Sbjct: 439  --GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQ 496

Query: 483  ALCTA--TSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR----PPRLRFAG--- 533
              C    + CV + +CF+Y   A   +Y   + L Y L+AD DRR     PR+ F     
Sbjct: 497  PNCAGGHSVCVDLRVCFSY--IAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNL 554

Query: 534  ----SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLR 589
                 +++         +  C      L +N++DKLR I+++++YSL      R   G  
Sbjct: 555  EEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQG 614

Query: 590  SLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQM-RAAFVSE-QQQKLSRLQYSR 646
                 PILN  Q      E+ F K+ CG D  C+SNLQ+ RA F +     +   L    
Sbjct: 615  LPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDV 674

Query: 647  DVRKLL----------LSINVTNTRTS----ERSGEDAHEALLTLVVPPALLLSSVR--- 689
            D    L          L + VTN  +     +  G+DAHEA L +++P +L  S VR   
Sbjct: 675  DGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALD 734

Query: 690  --PPGACQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQ 744
                  C +NE    + CELGNP KR  ++   +     G+++ T +L+V+L L+T S Q
Sbjct: 735  PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQ 794

Query: 745  DNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPM 804
            + L P+     V   L  S++ +    Q FF G V GE  M++  DVGS +KYE  V   
Sbjct: 795  E-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQ 853

Query: 805  GEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWP-----CRPPGDLINPLNLT 859
            G+ L  LG+  L + WP+E++NGKWLLYP ++ + G G  P     C P  ++++ L++ 
Sbjct: 854  GQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEG-GQGPGQKGLCSPRPNILH-LDV- 910

Query: 860  LSDPGDRPSSPQRRRRQLDPGGGQGP-----PPVT---LAAAKKAKSETVLTCATGRAHC 911
                     S  RRRR+L+P   Q P     P ++   +++A+K K+ T L CA G A+C
Sbjct: 911  --------DSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT-LDCARGTANC 961

Query: 912  VWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKT 971
            V   CP+        + V  R+WNSTF+E+Y     + V   A + +++SI  + + + +
Sbjct: 962  VVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDAS 1021

Query: 972  TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023
            T   V +  + +  +   +  W++L+AV AGLL+L L++LLLWK GFFKRA+
Sbjct: 1022 TVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1073


>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
          Length = 1044

 Score =  522 bits (1344), Expect = e-148
 Identities = 344/960 (35%), Positives = 520/960 (54%), Gaps = 102/960 (10%)

Query: 140  CAHRYT------QVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNEMCNSNTD-YL 192
            CAHRY       Q+L     + R M+G+C+V   DL +    D   +  + C      + 
Sbjct: 43   CAHRYEARQRVDQIL-----ETRDMIGRCFVLSQDLAIRDELDGGEW--KFCEGRPQGHE 95

Query: 193  ETGMCQLGTSGGFTQNTVY--FGAPGAYNWKGNSYM------------IQRKEWDLSEYS 238
            + G CQ GT+  F+ ++ Y  FGAPG YNWKG + +            +    ++     
Sbjct: 96   QFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEK 155

Query: 239  YKDPE---DQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRR 295
             +DP       N Y G+++  G  ++  + ++ V GAPR  H GAV +L +++   L   
Sbjct: 156  EQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPE 215

Query: 296  QVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPA 355
             +L G ++ + FG ++A+ADLN+DGW DL+VGAPY+FER+EE+GGA+YV++NQ G     
Sbjct: 216  VMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGI 275

Query: 356  HPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQ 415
             P L L G   S FG+S+A +GD+NQDGF DIAVGAPF+G GKV+IYH SS G++ +P Q
Sbjct: 276  SP-LRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQ 334

Query: 416  VIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLV 474
            V+ GE +   G+ +FGYSLSG +D+D N YPDLLVGSL+D  VL RARP++++ H+ ++ 
Sbjct: 335  VLEGEAV---GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIA 391

Query: 475  PRPAVLDPALCTA--TSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR----PPR 528
            PR   L+   C    + CV + +CF+Y   A   +Y   + L Y L+AD DRR     PR
Sbjct: 392  PRSIDLEQPNCAGGHSVCVDLRVCFSY--IAVPSSYSPTVALDYVLDADTDRRLRGQVPR 449

Query: 529  LRFAG-------SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581
            + F          +++         +  C      L +N++DKLR I+++++YSL     
Sbjct: 450  VTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRL 509

Query: 582  DRPRLGLRSLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQM-RAAFVSE-QQQK 638
             R   G       PILN  Q      E+ F K+ CG D  C+SNLQ+ RA F +     +
Sbjct: 510  RRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE 569

Query: 639  LSRLQYSRDVRKLL----------LSINVTNTRTS----ERSGEDAHEALLTLVVPPALL 684
               L    D    L          L + VTN  +     +  G+DAHEA L +++P +L 
Sbjct: 570  FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLH 629

Query: 685  LSSVR-----PPGACQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQL 736
             S VR         C +NE    + CELGNP KR  ++   +     G+++ T +L+V+L
Sbjct: 630  YSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVEL 689

Query: 737  QLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLK 796
             L+T S Q+ L P+     V   L  S++ +    Q FF G V GE  M++  DVGS +K
Sbjct: 690  LLATISEQE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVK 748

Query: 797  YEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWP-----CRPPGD 851
            YE  V   G+ L  LG+  L + WP+E++NGKWLLYP ++ + G G  P     C P  +
Sbjct: 749  YEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEG-GQGPGQKGLCSPRPN 807

Query: 852  LINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGP-----PPVT---LAAAKKAKSETVLT 903
            +++ L++          S  RRRR+L+P   Q P     P ++   +++A+K K+ T L 
Sbjct: 808  ILH-LDV---------DSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT-LD 856

Query: 904  CATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIP 963
            CA G A+CV   CP+        + V  R+WNSTF+E+Y     + V   A + +++SI 
Sbjct: 857  CARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIK 916

Query: 964  TINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023
             + + + +T   V +  + +  +   +  W++L+AV AGLL+L L++LLLWK GFFKRA+
Sbjct: 917  NLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 976


>gi|49170034 integrin, alpha 8 [Homo sapiens]
          Length = 1063

 Score =  289 bits (740), Expect = 8e-78
 Identities = 307/1106 (27%), Positives = 491/1106 (44%), Gaps = 146/1106 (13%)

Query: 1    MGPGPSRAPRAPRLMLCA-LALMVAAGGCVV-----SAFNLDTRFLVVKEAGNPGSLFGY 54
            M PG SR PR  +  L A L    AA G ++      AFNLD   L V  +G  GS FGY
Sbjct: 1    MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVY-SGPKGSYFGY 59

Query: 55   SVALHRQTERQQRYLLLAGAPR-ELAVPDGYTNRTGAVYLCPLTAHKD-DCERMNITVKN 112
            +V  H    R     +L GAP+   + PD      GAVY CP  A     C ++     N
Sbjct: 60   AVDFHIPDARTAS--VLVGAPKANTSQPDIVEG--GAVYYCPWPAEGSAQCRQIPFDTTN 115

Query: 113  DPGHHI------IE---DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSED--QRRMVGK 161
            +    +      IE   + W G TV +    G+V+ CA  Y    W   +   ++  VG 
Sbjct: 116  NRKIRVNGTKEPIEFKSNQWFGATVKAH--KGKVVACAPLYH---WRTLKPTPEKDPVGT 170

Query: 162  CYVRGNDLELDSSDDWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQN-TVYFGAPGAYNW 220
            CYV   +    +        +   NSN D    G CQ G S  F +N  +  G PG++ W
Sbjct: 171  CYVAIQNFSAYAE------FSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYW 224

Query: 221  KGNSYMIQRKEWDL-SEYSYKD--------------PEDQGNLYIGYTMQVGSFILHPKN 265
            +G   +I     D+ + YS+KD              P    + Y+GY++  G F    + 
Sbjct: 225  QGQ--VITASVADIIANYSFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQ 282

Query: 266  ITIVTGAPRH-RHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDL 324
              +V G PR  ++ G V +++     D+   Q   G Q+ +YFG  + ++D+N+DG  D+
Sbjct: 283  -ELVAGIPRGAQNFGYVSIINST---DMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDV 338

Query: 325  LVGAPYYFERKEEVG----GAIYVFMNQAGTSFPAHPSLLLHGPSGSAFGLSVASIGDIN 380
            LVGAP + ER+ E      G IY+++  +   F   P +L    +   FG ++A +GD+N
Sbjct: 339  LVGAPLFMEREFESNPREVGQIYLYLQVSSLLF-RDPQILTGTETFGRFGSAMAHLGDLN 397

Query: 381  QDGFQDIAVGAPFEGL---GKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQ 437
            QDG+ DIA+G PF G    GKV IY+ +  GL  +P QV+ G        + FG++L G 
Sbjct: 398  QDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGD 457

Query: 438  MDVDENFYPDLLVGSL-SDHIVLLRARPVINIVHKTLVPRPAVLD--------PALCTAT 488
             D+D+N YPDL+VG+  +  + + RARPV+ +  + L+  P +++        P   T+ 
Sbjct: 458  SDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLL-HPMIINLENKTCQVPDSMTSA 516

Query: 489  SCVQVELCFAYN-QSAGNPNYRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFFS 544
            +C  + +C +   QS  N      I L   ++ D  ++   ++   F  +  A  H  F 
Sbjct: 517  ACFSLRVCASVTGQSIAN-----TIVLMAEVQLDSLKQKGAIKRTLFLDNHQA--HRVFP 569

Query: 545  MPEMR-----CQKLELLLMDN--LRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPIL 597
            +   R     CQ   + L D    RDKL PI IS+NYSL              L+  PIL
Sbjct: 570  LVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLD------ESTFKEGLEVKPIL 623

Query: 598  NQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINV 657
            N  +      +     +CG DN C  +L++ A    ++ Q +       D   L+L IN 
Sbjct: 624  NYYRENIVSEQAHILVDCGEDNLCVPDLKLSAR--PDKHQVIIG-----DENHLMLIINA 676

Query: 658  TNTRTSERSGEDAHEALLTLVVPPALLLSSVRP------PGACQ-----ANETIFCELGN 706
             N       GE A+EA L +++P       +        P +C+         + C+LGN
Sbjct: 677  RN------EGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGN 730

Query: 707  PFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTL--QTSL 764
            P        L + F V  +      +   LQ+  SS++DN     ++L ++ T   Q  +
Sbjct: 731  PMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIR-SSNKDNPDSNFVSLQINITAVAQVEI 789

Query: 765  SMVNHRLQSFFG-GTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYE 823
              V+H  Q          E      E+VG  +++ +++  +G   +    L +G  WP+ 
Sbjct: 790  RGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVG--WPFS 847

Query: 824  VSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLT-LSDPGDRPSSPQRRRRQLDPGGG 882
              + ++LLY   I   G     C+P  + INP ++   + P D P      R    P   
Sbjct: 848  ARD-EFLLYIFHIQTLG--PLQCQPNPN-INPQDIKPAASPEDTPELSAFLRNSTIPHLV 903

Query: 883  QGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIE 940
            +    V +    +     +L C      C+ + C +   +      + V++R+W  TF++
Sbjct: 904  R-KRDVHVVEFHRQSPAKILNCTN--IECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQ 960

Query: 941  DYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPA---EIELWLVLV 997
              R  D   +    +  ++  +P  +   K    S+ I + ++   P     I LW++++
Sbjct: 961  --RKNDPYALASLVSFEVK-KMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIIL 1017

Query: 998  AVGAGLLLLGLIILLLWKCGFFKRAR 1023
            A+  GLL+L ++ L LWKCGFF RAR
Sbjct: 1018 AILLGLLVLAILTLALWKCGFFDRAR 1043


>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
          Length = 1035

 Score =  275 bits (704), Expect = 1e-73
 Identities = 274/1084 (25%), Positives = 477/1084 (44%), Gaps = 114/1084 (10%)

Query: 4    GPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTE 63
            GP+    A RL    LAL+VA  G    A+NLD +   V   G   S FGY+V  H    
Sbjct: 3    GPAAPRGAGRLRALLLALVVA--GIPAGAYNLDPQ-RPVHFQGPADSFFGYAVLEHFHDN 59

Query: 64   RQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDD-CERMNITVKNDPG------- 115
             +    +L GAP+  +         GAV+ C +  + D  C  +++    + G       
Sbjct: 60   TRW---VLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTC 116

Query: 116  HHIIEDMWLGVTVASQGPA-GRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSS 174
                +D W+GV++A Q  A GRVL CAHR+  + +    D     G CY+  ++L+    
Sbjct: 117  REDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEA--DHILPHGFCYIIPSNLQAKGR 174

Query: 175  DDWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDL 234
                 Y         ++   G CQ G +G FT+  V  GAPG++ W G   ++     +L
Sbjct: 175  TLIPCYEEYKKKYGEEH---GSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVL-----NL 226

Query: 235  SEYSYKDPEDQGNL-----YIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLL-SQEA 288
            ++ +Y    D+  +     Y+GY +  G F  HP  I +V GAP+ + +G V++  +   
Sbjct: 227  TDNTYLKLNDEVIMNRRYTYLGYAVTAGHFS-HPSTIDVVGGAPQDKGIGKVYIFRADRR 285

Query: 289  GGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQ 348
             G L +     G ++G+YFGS++   DLN DG  DLLVGAP + E ++E  G + V++N+
Sbjct: 286  SGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE--GQVTVYINR 343

Query: 349  AGTSFPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSS 406
               +     +L   G   + FG S+AS+ D++ DGF D+A+GAP E    G VYIYH  +
Sbjct: 344  GNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDA 403

Query: 407  KGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGS-LSDHIVLLRARPV 465
             G++ Q    + G+K+  P L  FG S+SG +D+D N YPD+ VG+ +SD +VLLRARPV
Sbjct: 404  GGIVPQYSMKLSGQKIN-PVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPV 462

Query: 466  INIVHKTLVPRPAVLDPALC----TATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEAD 521
            I +     +P    +    C       +C+ V  CF+++      +    I L Y L AD
Sbjct: 463  ITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFH----GKHVPGEIGLNYVLMAD 518

Query: 522  RDRRP----PRLRFA------GSESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIIS 571
              ++     PR+ F       G  +       +  E  C+     +   ++D + PI+  
Sbjct: 519  VAKKEKGQMPRVYFVLLGETMGQVTEKLQ--LTYMEETCRHYVAHVKRRVQDVISPIVFE 576

Query: 572  MNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAF 631
              YSL   +       L  L       + Q +    +  F++ C  ++ C ++LQ++   
Sbjct: 577  AAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED-CAADLQLQGKL 635

Query: 632  VSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPP 691
            +     + +       V+ + L+I+++N       G+DA++A ++  V   L   ++   
Sbjct: 636  LLSSMDEKTLYLALGAVKNISLNISISNL------GDDAYDANVSFNVSRELFFINMWQK 689

Query: 692  G----ACQANETIF--CELGNPFKRNQ-RMELLIAFEVIGVTLHTRDLQ--VQLQLSTSS 742
                 +C+  E+ F  C +G PF R++ + E  + F+   ++     L   V  Q   + 
Sbjct: 690  EEMGISCELLESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTE 749

Query: 743  HQDNLWPMILTLLVD--YTLQTSLSMVNHRLQSFFGGTVMGES--GMKTVEDVGSPLKYE 798
              ++L    L L+V   + + TS++ +       +G +V   +   +  +E    P+   
Sbjct: 750  RSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINIT 809

Query: 799  FQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITV----HGNGSWPCRPPGDLIN 854
             QV   G     L    + + +P  +S+G   ++  +  V     GN S+   P   +I 
Sbjct: 810  LQVYNTGPST--LPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCII- 866

Query: 855  PLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWL 914
                           PQ +               T+ A        VL C      C+  
Sbjct: 867  ---------------PQEQENIFH----------TIFAFFTKSGRKVLDCEKPGISCLTA 901

Query: 915  ECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWF 974
             C         + T+   +  +T I        ++    A + +  ++  + + +     
Sbjct: 902  HCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNP-E 960

Query: 975  SVDIDSELVEELPAE--IELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKR 1032
             V +  E +  L     +  W++ +++  G+L+  L+ +LLWK GFF+R R + + EA++
Sbjct: 961  EVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRR-RYKEIIEAEK 1019

Query: 1033 QKAE 1036
             + E
Sbjct: 1020 NRKE 1023


>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
          Length = 1048

 Score =  270 bits (690), Expect = 5e-72
 Identities = 301/1095 (27%), Positives = 476/1095 (43%), Gaps = 162/1095 (14%)

Query: 9    PRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRY 68
            PR   L+L  L L +        AFNLD      + +G  GS FG++V     +    R 
Sbjct: 13   PRGLPLLLSGLLLPLCR------AFNLDVDS-PAEYSGPEGSYFGFAVDFFVPSA-SSRM 64

Query: 69   LLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITV-------KNDPGHHIIED 121
             LL GAP+      G     G V  C  ++ +  C+ +           K+DP       
Sbjct: 65   FLLVGAPKANTTQPGIVEG-GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDP-LEFKSH 121

Query: 122  MWLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRGNDLELDSSDDWQTY 180
             W G +V S+    ++L CA  Y    W +  + +R  VG C+++         D  +T 
Sbjct: 122  QWFGASVRSK--QDKILACAPLYH---WRTEMKQEREPVGTCFLQ---------DGTKTV 167

Query: 181  HNEMCNS-NTDYLETGMCQLGTSGGFTQ-NTVYFGAPGAYNWKGNSYMIQRKE----WDL 234
                C S + D    G CQ G S  FT+ + V  G PG++ W+G     Q  E    +D 
Sbjct: 168  EYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDP 227

Query: 235  SEYSYKDPEDQG---------NLYIGYTMQVGSFILHPKNIT-IVTGAPRH-RHMGAVFL 283
            + YS K               + Y+GY++ VG F  +   I   V+G PR  R +G V++
Sbjct: 228  NVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDF--NGDGIDDFVSGVPRAARTLGMVYI 285

Query: 284  LSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER----KEEVG 339
                 G ++       G Q+ AYFG ++A  D+N D + D+ +GAP + +R    K +  
Sbjct: 286  YD---GKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEV 342

Query: 340  GAIYVFMNQAGTSFPAHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEGLGK 398
            G + V + +A   F    +  L+G    A FG ++A +GD++QDGF DIA+ AP+ G  K
Sbjct: 343  GQVSVSLQRASGDFQ---TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDK 399

Query: 399  ---VYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLS- 454
               VYI++  S GL   P Q++ G+        +FGYS+ G  D+D+N YPDL+VG+   
Sbjct: 400  KGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGV 459

Query: 455  DHIVLLRARPVINIVHKTLVPRPAVLD--------PALCTATSCVQVELCFAYNQSAGNP 506
            D  +L RARPVI  V+  L   P++L+        P      SC  V  C    ++ G  
Sbjct: 460  DRAILYRARPVIT-VNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCL---KADGKG 515

Query: 507  NYRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFFSMPE---MRCQKLELLLMD- 559
               R +     L  D+ ++   +R   F  S S       ++     M+C++L   L D 
Sbjct: 516  VLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDE 575

Query: 560  -NLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPD 618
               RDKL PI I M Y L  R       GL+     PILNQ        +     +CG D
Sbjct: 576  SEFRDKLTPITIFMEYRLDYRTA-ADTTGLQ-----PILNQFTPANISRQAHILLDCGED 629

Query: 619  NKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLV 678
            N C+  L++    V   Q+K+    Y  D   L L +   N       GE A+EA L + 
Sbjct: 630  NVCKPKLEVS---VDSDQKKI----YIGDDNPLTLIVKAQN------QGEGAYEAELIVS 676

Query: 679  VP-PALLLSSVRPPGAC--------QANET--IFCELGNPFKRNQRMELLIAFEVIGVTL 727
            +P  A  +  VR   A           N+T  + C+LGNP K   ++   + F V   + 
Sbjct: 677  IPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSE 736

Query: 728  HTRDLQVQLQLSTSSHQDNLWPMI-----LTLLVDYTLQTSLSMVNHRLQSFFGGTVMGE 782
                ++  LQ+ +S+  D + P++     L +L    ++  +S  +H            +
Sbjct: 737  MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIR-GVSSPDHIFLPI--PNWEHK 793

Query: 783  SGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNG 842
               +T EDVG  +++ +++     G       +L L+WPY+ +N   LLY     + G  
Sbjct: 794  ENPETEEDVGPVVQHIYEL--RNNGPSSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG-- 848

Query: 843  SWPCRPPGDL-INPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSE-T 900
              P     D+ INPL + +S          +   + D   GQG     +     A SE  
Sbjct: 849  --PMNCTSDMEINPLRIKISS--------LQTTEKNDTVAGQGERDHLITKRDLALSEGD 898

Query: 901  VLTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL-- 956
            + T   G A C+ + C +   D      + VK+ +W  TF+          +   A+   
Sbjct: 899  IHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNV 958

Query: 957  --FLRTSIPTINMENKT------TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGL 1008
              F   ++P  ++ N T      TW         ++  P  + +W++++AV AGLLLL +
Sbjct: 959  IEFPYKNLPIEDITNSTLVTTNVTWG--------IQPAPMPVPVWVIILAVLAGLLLLAV 1010

Query: 1009 IILLLWKCGFFKRAR 1023
            ++ ++++ GFFKR R
Sbjct: 1011 LVFVMYRMGFFKRVR 1025


>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
          Length = 1039

 Score =  269 bits (687), Expect = 1e-71
 Identities = 303/1074 (28%), Positives = 466/1074 (43%), Gaps = 158/1074 (14%)

Query: 32   AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91
            A NLD   L    AG  GS FG+S+  H+ +    R  ++ GAPR L         TG V
Sbjct: 31   ALNLDPVQLTFY-AGPNGSQFGFSLDFHKDSHG--RVAIVVGAPRTLGPSQ---EETGGV 84

Query: 92   YLCPLTAHKDDCERMNITVKNDP---GHHIIEDM----WLGVTVASQGPAGRVLVCAH-R 143
            +LCP  A    C  +   ++++    G   ++       LG +V S      ++ CA  +
Sbjct: 85   FLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDV--IVACAPWQ 142

Query: 144  YTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNEMCNSNT---DYLETGM---- 196
            +  VL    E ++  VG C+       L   +  +      C  NT    Y+E       
Sbjct: 143  HWNVLEKTEEAEKTPVGSCF-------LAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195

Query: 197  --CQLGTSGGFTQ-NTVYFGAPGAYNWKG-----------NSYMIQRKEWDLSEYSYKDP 242
              C+ G S   TQ   +  GAPG Y + G           +SY      W +S  S    
Sbjct: 196  RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255

Query: 243  EDQGNL---YIGYTMQVGSFILHPKNITIVTGAPRHRH-MGAVFLLSQEAGGDLRRRQVL 298
                     Y GY++ VG F         V GAP     +GAV +L        +R   L
Sbjct: 256  SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY----YQRLHRL 311

Query: 299  EGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFE----RKEEVGGAIYVFMNQAGTSFP 354
             G Q+ +YFG ++A+ D+N DG  DLLVGAP Y E    RK    G +Y+F+   G    
Sbjct: 312  RGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHAL 371

Query: 355  AHPSLLLHGPS-GSAFGLSVASIGDINQDGFQDIAVGAPF---EGLGKVYIYHSSSKGLL 410
              PSLLL G      FG ++A +GD+++DG+ DIAV AP+    G G+V ++   S+GL 
Sbjct: 372  GAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLR 431

Query: 411  RQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSL-SDHIVLLRARPVINIV 469
             +P QV+       P  + FG+SL G +D+D+N YPDL+VG+  ++ + + RA+PV+   
Sbjct: 432  SRPSQVLDSP---FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKAS 488

Query: 470  HKTLVP---RPAVLD---PALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRD 523
             + LV     PAV     P   T  SC  +++C      A   N  + ++L   L+ DR 
Sbjct: 489  VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCV----GATGHNIPQKLSLNAELQLDRQ 544

Query: 524  --RRPPRLRFAGSESA---VFHGFFSMPEMRCQKLELLLMD--NLRDKLRPIIISMNYSL 576
              R+  R+   GS+ A   +           C      L D  + RDKL PI++S+N SL
Sbjct: 545  KPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSL 604

Query: 577  PLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQK----ECGPDNKCESNLQMRAAFV 632
            P   P    +             A  L   T VQ Q     +CG D+ C   LQ+ A+  
Sbjct: 605  P---PTEAGMA-----------PAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVT 650

Query: 633  SEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL----LLSSV 688
                   S L    D   L L ++  N       GE A+EA L + +P        LS+V
Sbjct: 651  G------SPLLVGAD-NVLELQMDAAN------EGEGAYEAELAVHLPQGAHYMRALSNV 697

Query: 689  RP-----PGACQANET--IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTS 741
                       + NET  + CELGNP K+N ++ + +   V  +      +  QLQ+ + 
Sbjct: 698  EGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSK 757

Query: 742  SHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM----GESGMKTVEDVGSPLKY 797
            + Q+   P    +L+D  ++   + V  R  SF    V+    GE    +++  G  +++
Sbjct: 758  NSQN---PNSKIVLLDVPVRAE-AQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEH 813

Query: 798  EFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLN 857
             +++   G G V    L L +  P + S    LLY  +I   G      +PP   +NPL 
Sbjct: 814  TYELHNNGPGTV--NGLHLSIHLPGQ-SQPSDLLYILDIQPQGGLQCFPQPP---VNPLK 867

Query: 858  LT--LSDPGDRPSSP---QRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCV 912
            +   L  P   P  P   +R RRQ+     + P         + +   +++C +  A C 
Sbjct: 868  VDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQP--------SRLQDPVLVSCDS--APCT 917

Query: 913  WLECPIPDAP--VVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL-FLRTSIPTINMEN 969
             ++C + +        VTV A +W  +  +   D   ++ + W  +  L  ++P +++  
Sbjct: 918  VVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPR 977

Query: 970  KTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023
                    +   L E     I +W VLV V  GLLLL +++L +WK GFFKR R
Sbjct: 978  GEAQVWTQLLRALEER---AIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028


>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
          Length = 1002

 Score =  260 bits (665), Expect = 4e-69
 Identities = 284/1037 (27%), Positives = 452/1037 (43%), Gaps = 154/1037 (14%)

Query: 67   RYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITV-------KNDPGHHII 119
            R  LL GAP+      G     G V  C  ++ +  C+ +           K+DP     
Sbjct: 17   RMFLLVGAPKANTTQPGIVEG-GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDP-LEFK 73

Query: 120  EDMWLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRGNDLELDSSDDWQ 178
               W G +V S+    ++L CA  Y    W +  + +R  VG C+++         D  +
Sbjct: 74   SHQWFGASVRSK--QDKILACAPLYH---WRTEMKQEREPVGTCFLQ---------DGTK 119

Query: 179  TYHNEMCNS-NTDYLETGMCQLGTSGGFTQ-NTVYFGAPGAYNWKGNSYMIQRKE----W 232
            T     C S + D    G CQ G S  FT+ + V  G PG++ W+G     Q  E    +
Sbjct: 120  TVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKY 179

Query: 233  DLSEYSYKDPEDQG---------NLYIGYTMQVGSFILHPKNIT-IVTGAPRH-RHMGAV 281
            D + YS K               + Y+GY++ VG F  +   I   V+G PR  R +G V
Sbjct: 180  DPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDF--NGDGIDDFVSGVPRAARTLGMV 237

Query: 282  FLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER----KEE 337
            ++     G ++       G Q+ AYFG ++A  D+N D + D+ +GAP + +R    K +
Sbjct: 238  YIYD---GKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQ 294

Query: 338  VGGAIYVFMNQAGTSFPAHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEGL 396
              G + V + +A   F    +  L+G    A FG ++A +GD++QDGF DIA+ AP+ G 
Sbjct: 295  EVGQVSVSLQRASGDFQ---TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGE 351

Query: 397  GK---VYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSL 453
             K   VYI++  S GL   P Q++ G+        +FGYS+ G  D+D+N YPDL+VG+ 
Sbjct: 352  DKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAF 411

Query: 454  S-DHIVLLRARPVINIVHKTLVPRPAVLD--------PALCTATSCVQVELCFAYNQSAG 504
              D  +L RARPVI  V+  L   P++L+        P      SC  V  C    ++ G
Sbjct: 412  GVDRAILYRARPVIT-VNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCL---KADG 467

Query: 505  NPNYRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFFSMPE---MRCQKLELLLM 558
                 R +     L  D+ ++   +R   F  S S       ++     M+C++L   L 
Sbjct: 468  KGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLR 527

Query: 559  D--NLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECG 616
            D    RDKL PI I M Y L  R       GL+     PILNQ        +     +CG
Sbjct: 528  DESEFRDKLTPITIFMEYRLDYRTA-ADTTGLQ-----PILNQFTPANISRQAHILLDCG 581

Query: 617  PDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLT 676
             DN C+  L++    V   Q+K+    Y  D   L L +   N       GE A+EA L 
Sbjct: 582  EDNVCKPKLEVS---VDSDQKKI----YIGDDNPLTLIVKAQN------QGEGAYEAELI 628

Query: 677  LVVP-PALLLSSVRPPGAC--------QANET--IFCELGNPFKRNQRMELLIAFEVIGV 725
            + +P  A  +  VR   A           N+T  + C+LGNP K   ++   + F V   
Sbjct: 629  VSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQ 688

Query: 726  TLHTRDLQVQLQLSTSSHQDNLWPMI-----LTLLVDYTLQTSLSMVNHRLQSFFGGTVM 780
            +     ++  LQ+ +S+  D + P++     L +L    ++  +S  +H           
Sbjct: 689  SEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIR-GVSSPDHIFLPI--PNWE 745

Query: 781  GESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHG 840
             +   +T EDVG  +++ +++     G       +L L+WPY+ +N   LLY     + G
Sbjct: 746  HKENPETEEDVGPVVQHIYEL--RNNGPSSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG 802

Query: 841  NGSWPCRPPGDL-INPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSE 899
                P     D+ INPL + +S          +   + D   GQG     +     A SE
Sbjct: 803  ----PMNCTSDMEINPLRIKISS--------LQTTEKNDTVAGQGERDHLITKRDLALSE 850

Query: 900  -TVLTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL 956
              + T   G A C+ + C +   D      + VK+ +W  TF+          +   A+ 
Sbjct: 851  GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASF 910

Query: 957  ----FLRTSIPTINMENKT------TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLL 1006
                F   ++P  ++ N T      TW         ++  P  + +W++++AV AGLLLL
Sbjct: 911  NVIEFPYKNLPIEDITNSTLVTTNVTWG--------IQPAPMPVPVWVIILAVLAGLLLL 962

Query: 1007 GLIILLLWKCGFFKRAR 1023
             +++ ++++ GFFKR R
Sbjct: 963  AVLVFVMYRMGFFKRVR 979


>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
          Length = 1049

 Score =  258 bits (660), Expect = 2e-68
 Identities = 306/1109 (27%), Positives = 462/1109 (41%), Gaps = 158/1109 (14%)

Query: 4    GPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTE 63
            GP R P    L+L  L      GG     FNLD     V  +G PGS FG+SV  +R   
Sbjct: 18   GPRRRPPLLPLLLLLLPPPPRVGG-----FNLDAEAPAVL-SGPPGSFFGFSVEFYRPGT 71

Query: 64   RQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIED-- 121
                  +L GAP+      G   + GAVYLCP  A    C  +    K   G  ++E   
Sbjct: 72   --DGVSVLVGAPKANTSQPGVL-QGGAVYLCPWGASPTQCTPIEFDSK---GSRLLESSL 125

Query: 122  --------------MWLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRG 166
                           W G TV + G +  +L CA  Y+   W +  E     VG CY+  
Sbjct: 126  SSSEGEEPVEYKSLQWFGATVRAHGSS--ILACAPLYS---WRTEKEPLSDPVGTCYL-- 178

Query: 167  NDLELDSSDDW-QTYHNEMCNSNTDYLE-TGMCQLGTSGGFTQN-TVYFGAPGAYNWKGN 223
                  S+D++ +      C S+  +    G CQ G S  FT+   V  G PG+Y W+G 
Sbjct: 179  ------STDNFTRILEYAPCRSDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQ 232

Query: 224  SYMIQRKEWDLSEY-SYKDPEDQGNL------------YIGYTMQVGSFILHPKNITIVT 270
                 +++   S Y  Y     QG L            Y+GY++ VG F         V 
Sbjct: 233  ILSATQEQIAESYYPEYLINLVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTE-DFVA 291

Query: 271  GAPR-HRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAP 329
            G P+ +   G V +L+   G D+R      G Q+ +YFG A+A  D+N DG  DLLVGAP
Sbjct: 292  GVPKGNLTYGYVTILN---GSDIRSLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAP 348

Query: 330  YYFER----KEEVGGAIYVFMNQAGTSFPAHPSLLLHG-PSGSAFGLSVASIGDINQDGF 384
               +R    + +  G +YV++       P  P+L L G      FG S+  +GD++QDG+
Sbjct: 349  LLMDRTPDGRPQEVGRVYVYLQHPAGIEPT-PTLTLTGHDEFGRFGSSLTPLGDLDQDGY 407

Query: 385  QDIAVGAPFEG---LGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVD 441
             D+A+GAPF G    G V+++     GL  +P QV+            FG +L G  D+D
Sbjct: 408  NDVAIGAPFGGETQQGVVFVFPGGPGGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLD 467

Query: 442  ENFYPDLLVGSLS-DHIVLLRARPVINIVHKTLVPRPAVLDP--ALCT----ATSCVQVE 494
             N YPDL+VGS   D  V+ R RP+++    +L   PA+ +P    C+      +C+ + 
Sbjct: 468  GNGYPDLIVGSFGVDKAVVYRGRPIVS-ASASLTIFPAMFNPEERSCSLEGNPVACINLS 526

Query: 495  LCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFF-----SMP 546
             C     +A   +   +I     L+ D  ++   +R   F  S  A           +  
Sbjct: 527  FCL----NASGKHVADSIGFTVELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGARE 582

Query: 547  EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENH 606
            + R  K+ L      RDKL PI I++N+SL  + P     GLR     P L+        
Sbjct: 583  DCREMKIYLRNESEFRDKLSPIHIALNFSLDPQAPVDSH-GLR-----PALHYQSKSRIE 636

Query: 607  TEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERS 666
             + Q   +CG DN C  +LQ+      EQ        Y  D   L L+ +  N       
Sbjct: 637  DKAQILLDCGEDNICVPDLQLEV--FGEQNH-----VYLGDKNALNLTFHAQNV------ 683

Query: 667  GE-DAHEALLTLVVPPALLLSS-VRPPG----------ACQANETIFCELGNPFKRNQRM 714
            GE  A+EA L +  PP    S  VR PG          A   +  + C+LGNP K    +
Sbjct: 684  GEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLLVCDLGNPMKAGASL 743

Query: 715  ELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMI-LTLLVDYTLQTSLSMVNHRLQS 773
               + F V  +    + +Q   Q+ + +  ++   ++   L V+   Q +L+ V+     
Sbjct: 744  WGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSVEAQAQVTLNGVSKPEAV 803

Query: 774  FFGGTVMGESGM-KTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLY 832
             F  +        +  ED+G  + + +++   G   +  G L L      E   G+ LLY
Sbjct: 804  LFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPSSISQGVLELSCPQALE---GQQLLY 860

Query: 833  PTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAA 892
             T +T  G       P    INP  L L DP       Q+R          GP       
Sbjct: 861  VTRVT--GLNCTTNHP----INPKGLEL-DPEGSLHHQQKREAPSRSSASSGP------- 906

Query: 893  AKKAKSETVLTCATGRAHCVWLECPIPDAPVVTNVTVKA--RVWNSTFIE-DYRDFDRVR 949
                    +L C    A C  L C +       + +++   RVW  TF++ +++ F    
Sbjct: 907  -------QILKCP--EAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQPFSLQC 957

Query: 950  VNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLI 1009
               +  L +   I    +  K    +  +     E     + LW++++A+  GLLLLGL+
Sbjct: 958  EAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEG-SYGVPLWIIILAILFGLLLLGLL 1016

Query: 1010 ILLLWKCGFFKRARTRALYEAKRQKAEMK 1038
            I +L+K GFFKR+     Y    +KA++K
Sbjct: 1017 IYILYKLGFFKRSLP---YGTAMEKAQLK 1042


>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
          Length = 1012

 Score =  248 bits (634), Expect = 2e-65
 Identities = 287/1080 (26%), Positives = 463/1080 (42%), Gaps = 168/1080 (15%)

Query: 9    PRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRY 68
            PR   L+L  L L +        AFNLD      + +G  GS FG++V     +    R 
Sbjct: 13   PRGLPLLLSGLLLPLCR------AFNLDVDS-PAEYSGPEGSYFGFAVDFFVPSA-SSRM 64

Query: 69   LLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITV-------KNDPGHHIIED 121
             LL GAP+      G     G V  C  ++ +  C+ +           K+DP       
Sbjct: 65   FLLVGAPKANTTQPGIVEG-GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDP-LEFKSH 121

Query: 122  MWLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRGNDLELDSSDDWQTY 180
             W G +V S+    ++L CA  Y    W +  + +R  VG C+++         D  +T 
Sbjct: 122  QWFGASVRSK--QDKILACAPLYH---WRTEMKQEREPVGTCFLQ---------DGTKTV 167

Query: 181  HNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYK 240
                C S    +   + ++ +             P  Y+ K N+ +  R    + + SY 
Sbjct: 168  EYAPCRSR-QLISDQVAEIVSKYD----------PNVYSIKYNNQLATRTAQAIFDDSY- 215

Query: 241  DPEDQGNLYIGYTMQVGSFILHPKNIT-IVTGAPRH-RHMGAVFLLSQEAGGDLRRRQVL 298
                     +GY++ VG F  +   I   V+G PR  R +G V++     G ++      
Sbjct: 216  ---------LGYSVAVGDF--NGDGIDDFVSGVPRAARTLGMVYIYD---GKNMSSLYNF 261

Query: 299  EGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER----KEEVGGAIYVFMNQAGTSFP 354
             G Q+ AYFG ++A  D+N D + D+ +GAP + +R    K +  G + V + +A   F 
Sbjct: 262  TGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQ 321

Query: 355  AHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEGLGK---VYIYHSSSKGLL 410
               +  L+G    A FG ++A +GD++QDGF DIA+ AP+ G  K   VYI++  S GL 
Sbjct: 322  ---TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLN 378

Query: 411  RQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLS-DHIVLLRARPVINIV 469
              P Q++ G+        +FGYS+ G  D+D+N YPDL+VG+   D  +L RARPVI  V
Sbjct: 379  AVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVIT-V 437

Query: 470  HKTLVPRPAVLD--------PALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEAD 521
            +  L   P++L+        P      SC  V  C    ++ G     R +     L  D
Sbjct: 438  NAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCL---KADGKGVLPRKLNFQVELLLD 494

Query: 522  RDRRPPRLR---FAGSESAVFHGFFSMPE---MRCQKLELLLMD--NLRDKLRPIIISMN 573
            + ++   +R   F  S S       ++     M+C++L   L D    RDKL PI I M 
Sbjct: 495  KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 554

Query: 574  YSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVS 633
            Y L  R       GL+     PILNQ        +     +CG DN C+  L++    V 
Sbjct: 555  YRLDYRTA-ADTTGLQ-----PILNQFTPANISRQAHILLDCGEDNVCKPKLEVS---VD 605

Query: 634  EQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVP-PALLLSSVRPPG 692
              Q+K+    Y  D   L L +   N       GE A+EA L + +P  A  +  VR   
Sbjct: 606  SDQKKI----YIGDDNPLTLIVKAQN------QGEGAYEAELIVSIPLQADFIGVVRNNE 655

Query: 693  AC--------QANET--IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSS 742
            A           N+T  + C+LGNP K   ++   + F V   +     ++  LQ+ +S+
Sbjct: 656  ALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSN 715

Query: 743  HQDNLWPMI-----LTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKY 797
              D + P++     L +L    ++  +S  +H            +   +T EDVG  +++
Sbjct: 716  LFDKVSPVVSHKVDLAVLAAVEIR-GVSSPDHIFLPI--PNWEHKENPETEEDVGPVVQH 772

Query: 798  EFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDL-INPL 856
             +++     G       +L L+WPY+ +N   LLY     + G    P     D+ INPL
Sbjct: 773  IYEL--RNNGPSSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG----PMNCTSDMEINPL 825

Query: 857  NLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSE-TVLTCATGRAHCVWLE 915
             + +S          +   + D   GQG     +     A SE  + T   G A C+ + 
Sbjct: 826  RIKISS--------LQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIV 877

Query: 916  CPIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL----FLRTSIPTINMEN 969
            C +   D      + VK+ +W  TF+          +   A+     F   ++P  ++ N
Sbjct: 878  CQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITN 937

Query: 970  KT------TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023
             T      TW         ++  P  + +W++++AV AGLLLL +++ ++++ GFFKR R
Sbjct: 938  STLVTTNVTWG--------IQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVR 989


>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
          Length = 1032

 Score =  245 bits (625), Expect = 2e-64
 Identities = 223/805 (27%), Positives = 379/805 (47%), Gaps = 76/805 (9%)

Query: 3   PGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQT 62
           PGP RA     +ML  L L V  G      +N+DT   ++ + G   +LFGYSV LH   
Sbjct: 9   PGPRRAAVRETVMLL-LCLGVPTG----RPYNVDTESALLYQ-GPHNTLFGYSVVLHSHG 62

Query: 63  ERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDD-CERMNITVKNDP--GHHII 119
             +    LL GAP    + +      GA+Y C +  +    CE++ +   N    G   +
Sbjct: 63  ANRW---LLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCL 119

Query: 120 ED---MWLGVTVASQ-GPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSD 175
           E+    WLGVT++ Q G  G ++ C HR+  + +  +E+ +   G CY    DL  + S 
Sbjct: 120 EERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNEN-KLPTGGCYGVPPDLRTELSK 178

Query: 176 DWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLS 235
                + +      +   +  CQ G S  +T++ +  GAPG+  W G+ ++         
Sbjct: 179 RIAPCYQDYVKKFGENFAS--CQAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYK 236

Query: 236 EYSYKDPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRR 295
            +  K  + +   Y+GY++  G F        +V GAP+H  +G  ++ S +   +L   
Sbjct: 237 AFLDKQNQVKFGSYLGYSVGAGHF-RSQHTTEVVGGAPQHEQIGKAYIFSIDEK-ELNIL 294

Query: 296 QVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQ-AGTSFP 354
             ++G ++G+YFG+++   DLN DG+ DLLVGAP     +EE  G ++V++N  +G    
Sbjct: 295 HEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREE--GRVFVYINSGSGAVMN 352

Query: 355 AHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSSKGLLR 411
           A  + L+     +A FG S+ ++GDI+ DGF+D+A+GAP E    G +YIY+  + G+  
Sbjct: 353 AMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISS 412

Query: 412 QPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSL-SDHIVLLRARPVINIVH 470
              Q I G ++    L+ FG S+SGQ+D D N Y D+ VG+  SD  VLLR RPV+ +  
Sbjct: 413 TFSQRIEGLQIS-KSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDA 471

Query: 471 KTLVPRPAVLDPALCTATS----CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR- 525
               P         C        C+ + LCF+Y +    P Y   I L Y +  D +R+ 
Sbjct: 472 SLSHPESVNRTKFDCVENGWPSVCIDLTLCFSY-KGKEVPGY---IVLFYNMSLDVNRKA 527

Query: 526 --PPRLRFAGS-ESAVFHGFF--SMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRM 580
             PPR  F+ +  S V  G    S  E  C+  +  +  ++RD L PI I   Y L   +
Sbjct: 528 ESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHV 587

Query: 581 PDRPRLGLRSLDAY----PILNQAQALE-NHTEVQFQKECGPDNKCESNLQMRA--AFVS 633
                +  RS + +    PIL Q +  +     + F + C  +N C ++LQ+ A   F+ 
Sbjct: 588 -----ISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLK 641

Query: 634 EQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL----LLSSVR 689
             + K      S  ++ L+L++++ N      +G+DA+E  L + +P  L    +L    
Sbjct: 642 PHENKTYLAVGS--MKTLMLNVSLFN------AGDDAYETTLHVKLPVGLYFIKILELEE 693

Query: 690 PPGACQANET-----IFCELGNPFKRN-QRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH 743
               C+  +      + C +G  +  +  R+++    +V  ++    DL + +  +  + 
Sbjct: 694 KQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENE 753

Query: 744 Q--DNLWPMILTLLVDYTLQTSLSM 766
           +  DNL    +T+ +    +  L++
Sbjct: 754 EEMDNLKHSRVTVAIPLKYEVKLTV 778



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 5/42 (11%)

Query: 997  VAVGAGLLLLGLIILLL-----WKCGFFKRARTRALYEAKRQ 1033
            + + +  LLLGLI+LLL     WK GFFKR     L E  R+
Sbjct: 978  IVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRR 1019


>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
          Length = 1179

 Score =  233 bits (593), Expect = 9e-61
 Identities = 225/871 (25%), Positives = 369/871 (42%), Gaps = 115/871 (13%)

Query: 193  ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGN------SYMIQRKEWDLSEYSYKDPEDQG 246
            E  M Q G S  ++Q+ V  GA GAY+W G       S +I  +    +  S K  E   
Sbjct: 374  EMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLA 433

Query: 247  NLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAY 306
            + Y+GYT  V S      ++  + G PR+ H G V +   E  G+++  Q L G Q+G+Y
Sbjct: 434  S-YLGYT--VNSATASSGDVLYIAGQPRYNHTGQVIIYRME-DGNIKILQTLSGEQIGSY 489

Query: 307  FGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVF---------------MNQAG 350
            FGS +   D++ D   D LLVGAP Y   ++E  G +YV+               + Q  
Sbjct: 490  FGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTC 549

Query: 351  TSFPAHPSLLLHG---PSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSS 405
             S   H S        P G+ FG ++A++ D+N DGF DI +GAP E    G VYIYH S
Sbjct: 550  CSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGS 609

Query: 406  SKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPV 465
             K + ++  Q I     G   L  FG S+ G+MD++ +   D+ +G L    +       
Sbjct: 610  GKTIRKEYAQRIPSGGDG-KTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVA 668

Query: 466  INIVHKTLVPRPAVLDPALC----TATSCVQVELCFAYN-QSAGNPNYRRNITLAYTLEA 520
            +  V     P    +    C      T C+   +CF    +S  +  Y  +  L Y +  
Sbjct: 669  VVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEAD--LQYRVTL 726

Query: 521  DRDRRPPRLRFAGSESAVFHGFFSMPEMRCQKLELLLMD--NLRDKLRPIIISMNYSLPL 578
            D  R+  R  F+G++        ++ +  C K    ++D  + +D +R   I+++++L  
Sbjct: 727  DSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDFNL-- 781

Query: 579  RMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQK 638
                 P  G       P+L+ +     H  + F K+CG   KC S+L +  A  +E+   
Sbjct: 782  ---TDPENG-------PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVA-TTEKDLL 830

Query: 639  LSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVR--PPGACQA 696
            + R Q      K  +S+ V NT+ S      A+     +   P L+ S +      +C++
Sbjct: 831  IVRSQND----KFNVSLTVKNTKDS------AYNTRTIVHYSPNLVFSGIEAIQKDSCES 880

Query: 697  NETIFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQ------DNLWPM 750
            N  I C++G PF R   M           +    ++ + L  ++ S +      DN+  +
Sbjct: 881  NHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNI 940

Query: 751  ILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVG 810
             + +  +  LQ   S   + +      TV     + + ED+G+ +   + +   G     
Sbjct: 941  SIPVKYEVGLQFYSSASEYHISIAANETV--PEVINSTEDIGNEINIFYLIRKSGS--FP 996

Query: 811  LGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSP 870
            +  L L + +P   SNG  +LYPT ++   N +  CRP             DP    S  
Sbjct: 997  MPELKLSISFPNMTSNGYPVLYPTGLSSSENAN--CRPH---------IFEDPFSINSGK 1045

Query: 871  QRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVTNVTVK 930
            +                    +    K  T+L C T +   +       D   ++ V V 
Sbjct: 1046 K-----------------MTTSTDHLKRGTILDCNTCKFATITCNLTSSD---ISQVNVS 1085

Query: 931  ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990
              +W  TFI+ Y  F  + +     L    +   ++  N+    ++ I     + LP  +
Sbjct: 1086 LILWKPTFIKSY--FSSLNLTIRGELRSENASLVLSSSNQKRELAIQISK---DGLPGRV 1140

Query: 991  ELWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021
             LW++L++  AGLLLL L+IL LWK GFFKR
Sbjct: 1141 PLWVILLSAFAGLLLLMLLILALWKIGFFKR 1171



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 16/147 (10%)

Query: 1   MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR 60
           M P P   P     + C   L V    CV  +FN+D +  +   +G    +FGY+V   +
Sbjct: 1   MAPRPRARPGVA--VACCWLLTVVLRCCV--SFNVDVKNSMTF-SGPVEDMFGYTV---Q 52

Query: 61  QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKD-DCERMNITVKNDPGH--H 117
           Q E ++   +L G+P  +  P    NRTG VY CP+   +   C ++++ V     +   
Sbjct: 53  QYENEEGKWVLIGSPL-VGQPK---NRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTE 108

Query: 118 IIEDMWLGVTVASQGPAGRVLVCAHRY 144
           + E+M  G T+ +  P G  L C   Y
Sbjct: 109 VKENMTFGSTLVT-NPNGGFLACGPLY 134


>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
          Length = 1167

 Score =  179 bits (453), Expect = 2e-44
 Identities = 158/592 (26%), Positives = 268/592 (45%), Gaps = 55/592 (9%)

Query: 196 MCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNL-----YI 250
           M Q+G S    ++ + FG  GAY+W G+   ++            + E    L     Y+
Sbjct: 372 MSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYL 431

Query: 251 GYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSA 310
           GY+  V S +L       ++GAPR RH G V     +  G +R  Q L+G Q+G+YFGS 
Sbjct: 432 GYS--VSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSE 489

Query: 311 IALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSGSAF 369
           +   D + DG  D LLV AP +   + +  G +YV++    +      +L    P  + F
Sbjct: 490 LCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARF 549

Query: 370 GLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGL 427
           G ++ ++ D+NQDGF D+AVGAP E    G +Y+YH +  G+   P Q I    +    L
Sbjct: 550 GFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMP-HAL 608

Query: 428 ATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLVPRPAVLDPALCT 486
           + FG S+ G++D+D +   D+ VG+     +LL +RP++++     + P+   +    C 
Sbjct: 609 SYFGRSVDGRLDLDGDDLVDVAVGA-QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCR 667

Query: 487 ATS----CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVF--H 540
                  C+   LCF    S     +     + +T   D      R  F GS   +    
Sbjct: 668 RRGQEAVCLTAALCFQVT-SRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRLSPRR 726

Query: 541 GFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQA 600
              S+  + C++L   ++D   D LRP+ +++ ++L             +    P+LN+ 
Sbjct: 727 LRLSVGNVTCEQLHFHVLDT-SDYLRPVALTVTFALD-----------NTTKPGPVLNEG 774

Query: 601 QALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNT 660
                   V F K+CGPDN+C ++L ++        +K +        RK+L+S  + N 
Sbjct: 775 SPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRK-APFVVRGGRRKVLVSTTLENR 833

Query: 661 RTSERSGEDAHEALLTLVVPPALLLSSVRPPG--------ACQANETIFCELGNP-FKRN 711
           +      E+A+   L+L+    L L+S+ P          A  +     C +G+P F+  
Sbjct: 834 K------ENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTG 887

Query: 712 QRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTS 763
            ++  L+ FE    +L ++ + V+L  S+ S + N        L D T QTS
Sbjct: 888 AKVTFLLEFEFSCSSLLSQ-VFVKLTASSDSLERN------GTLQDNTAQTS 932



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 23/54 (42%), Positives = 34/54 (62%), Gaps = 2/54 (3%)

Query: 981  ELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQK 1034
            E+V+  P  I LW+++ +V  GLLLL L++  LWK GFF  A  +   E KR++
Sbjct: 1112 EVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFF--AHKKIPEEEKREE 1163


>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
          Length = 1086

 Score =  176 bits (445), Expect = 1e-43
 Identities = 159/558 (28%), Positives = 253/558 (45%), Gaps = 62/558 (11%)

Query: 200 GTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSY-----KDPEDQGNLYIGYTM 254
           G S   ++     GA GA +W G    ++    DL + ++       PE +   Y+GYT 
Sbjct: 270 GISADLSRGHAVVGAVGAKDWAGGFLDLKA---DLQDDTFIGNEPLTPEVRAG-YLGYT- 324

Query: 255 QVGSFILHPKNITIVTGAPRHRHMGAVFLLSQ-EAGGDLRRRQVLEGSQVGAYFGSAIAL 313
            V       K   + +GAPR++HMG V L  + + GG   + Q + G+Q+G+YFG  +  
Sbjct: 325 -VTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCG 383

Query: 314 ADLNNDGWQDLL-VGAPYYFERKEEVGGAIYVFMN-QAGTSFPAHPSLLLHGPSG---SA 368
            D++ DG  +LL +GAP ++   E+ GG ++++   Q G    +     L G  G     
Sbjct: 384 VDVDQDGETELLLIGAPLFYG--EQRGGRVFIYQRRQLGFEEVSE----LQGDPGYPLGR 437

Query: 369 FGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLA 428
           FG ++ ++ DIN DG  D+AVGAP E  G VYI++    GL  QP Q I G ++ L G+ 
Sbjct: 438 FGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQV-LSGIQ 496

Query: 429 TFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVH-KTLVPRPAVLDPALCTA 487
            FG S+ G  D++ +   D+ VG+ S  IV L +RPV+++V   +  P    +    C+ 
Sbjct: 497 WFGRSIHGVKDLEGDGLADVAVGAESQMIV-LSSRPVVDMVTLMSFSPAEIPVHEVECSY 555

Query: 488 TSC------VQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFHG 541
           ++       V + +CF           R    L YTL+ D  R   R  F G    +   
Sbjct: 556 STSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRN 615

Query: 542 FFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQ 601
                 M C          ++D + PI +S+N+SL       PR      D  PIL  + 
Sbjct: 616 IAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSL-WEEEGTPRDQRAGKDIPPILRPSL 674

Query: 602 ALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTR 661
             E   E+ F+K CG D KCE+NL  R +F   + + L    ++     L + ++++N  
Sbjct: 675 HSET-WEIPFEKNCGEDKKCEANL--RVSFSPARSRALRLTAFA----SLSVELSLSNLE 727

Query: 662 TSERSGEDAHEALLTLVVPPALLLSSV-------RPPGACQ--------ANETIFCELGN 706
                 EDA+   L L  PP L    V       + P +C+         +  + C + +
Sbjct: 728 ------EDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSS 781

Query: 707 P-FKRNQRMELLIAFEVI 723
           P FK    + L + F  +
Sbjct: 782 PIFKAGHSVALQMMFNTL 799



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 16/30 (53%), Positives = 23/30 (76%)

Query: 992  LWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021
            L+L +++   GLLLL LI ++L+K GFFKR
Sbjct: 1006 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1035


>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
          Length = 1170

 Score =  173 bits (439), Expect = 7e-43
 Identities = 157/558 (28%), Positives = 252/558 (45%), Gaps = 61/558 (10%)

Query: 200 GTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSY-----KDPEDQGNLYIGYTM 254
           G S   ++     GA GA +W G    ++    DL + ++       PE +   Y+GYT 
Sbjct: 353 GISADLSRGHAVVGAVGAKDWAGGFLDLKA---DLQDDTFIGNEPLTPEVRAG-YLGYT- 407

Query: 255 QVGSFILHPKNITIVTGAPRHRHMGAVFLLSQ-EAGGDLRRRQVLEGSQVGAYFGSAIAL 313
            V       K   + +GAPR++HMG V L  + + GG   + Q + G+Q+G+YFG  +  
Sbjct: 408 -VTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCG 466

Query: 314 ADLNNDGWQDLL-VGAPYYFERKEEVGGAIYVFMN-QAGTSFPAHPSLLLHGPSG---SA 368
            D++ DG  +LL +GAP ++   E+ GG ++++   Q G    +     L G  G     
Sbjct: 467 VDVDQDGETELLLIGAPLFYG--EQRGGRVFIYQRRQLGFEEVSE----LQGDPGYPLGR 520

Query: 369 FGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLA 428
           FG ++ ++ DIN DG  D+AVGAP E  G VYI++    GL  QP Q I G ++ L G+ 
Sbjct: 521 FGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQV-LSGIQ 579

Query: 429 TFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVH-KTLVPRPAVLDPALCTA 487
            FG S+ G  D++ +   D+ VG+ S  IV L +RPV+++V   +  P    +    C+ 
Sbjct: 580 WFGRSIHGVKDLEGDGLADVAVGAESQMIV-LSSRPVVDMVTLMSFSPAEIPVHEVECSY 638

Query: 488 TSC------VQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFHG 541
           ++       V + +CF           R    L YTL+ D  R   R  F G    +   
Sbjct: 639 STSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRN 698

Query: 542 FFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQ 601
                 M C          ++D + PI +S+N+SL            +  D  PIL  + 
Sbjct: 699 IAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSL 758

Query: 602 ALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTR 661
             E   E+ F+K CG D KCE+NL  R +F   + + L    ++     L + ++++N  
Sbjct: 759 HSET-WEIPFEKNCGEDKKCEANL--RVSFSPARSRALRLTAFA----SLSVELSLSNLE 811

Query: 662 TSERSGEDAHEALLTLVVPPALLLSSV-------RPPGACQ--------ANETIFCELGN 706
                 EDA+   L L  PP L    V       + P +C+         +  + C + +
Sbjct: 812 ------EDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSS 865

Query: 707 P-FKRNQRMELLIAFEVI 723
           P FK    + L + F  +
Sbjct: 866 PIFKAGHSVALQMMFNTL 883



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 16/30 (53%), Positives = 23/30 (76%)

Query: 992  LWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021
            L+L +++   GLLLL LI ++L+K GFFKR
Sbjct: 1090 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1119


>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
          Length = 1188

 Score =  172 bits (435), Expect = 2e-42
 Identities = 186/703 (26%), Positives = 301/703 (42%), Gaps = 89/703 (12%)

Query: 183  EMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGN-------SYMIQRKEWDLS 235
            E  N N       M Q G S    ++ V  GA GAY+W G          +I  +E  L 
Sbjct: 353  EGTNKNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLK 412

Query: 236  EYSYKDPEDQGN--LYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLR 293
            E+    PE+  N   Y+GYT  V S +   +    V GAPR  H G V L +      L 
Sbjct: 413  EF----PEELKNHGAYLGYT--VTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLT 466

Query: 294  RRQVLEGSQVGAYFGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVFMNQAGTS 352
              Q + G Q+G+YFGS I   D++ DG  D LLVGAP YF    E  G +YV+  +    
Sbjct: 467  IHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRE-RGKVYVYELRQNLF 525

Query: 353  FPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSSKGLL 410
                     H    + FG S+AS+ D+NQD + D+ VGAP E    G +YI+H     +L
Sbjct: 526  VYNGTLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSIL 585

Query: 411  RQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVH 470
            + P+Q I   +L   GL  FG S+ GQ+D++E+   DL VG+L  + V+L +RPV+ I +
Sbjct: 586  KTPKQRITASELA-TGLQYFGCSIHGQLDLNEDGLIDLAVGALG-NAVILWSRPVVQI-N 642

Query: 471  KTLVPRPAVLD------PALCTATSCVQVELCFAYNQSAGNPNYR-RNITLAYTLEADRD 523
             +L   P+ ++             +C+   LCF     A  P+++   + + Y    D  
Sbjct: 643  ASLHFEPSKINIFHRDCKRSGRDATCLAAFLCFTPIFLA--PHFQTTTVGIRYNATMDER 700

Query: 524  RRPPR--LRFAGSESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581
            R  PR  L   G          S  +  C+++   ++D   D ++P+  S+ YS      
Sbjct: 701  RYTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDT-ADYVKPVTFSVEYS------ 753

Query: 582  DRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRA----AFVSEQQQ 637
                  L   D  P+L+          V F   C  D  C  +L + A        E  Q
Sbjct: 754  ------LEDPDHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQ 807

Query: 638  KLSRLQYSRDVRKLLLSINVT-----NTR-------TSERSGEDAHEALLTLVVPPALLL 685
            ++ R + ++D     LS + T     +TR       T E  GE+A+  +L +     L  
Sbjct: 808  RVLR-KPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQF 866

Query: 686  SS-VRPPGACQANETI---------FCELGNPFKR-NQRMELLIAFEVIGVTLHTRDLQV 734
            +S ++   +  + E +          C +  PF R   ++   + FE    ++    L++
Sbjct: 867  ASLIQKEDSDGSIECVNEERRLQKQVCNVSYPFFRAKAKVAFRLDFE-FSKSIFLHHLEI 925

Query: 735  QLQLSTSSH------QDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTV 788
            +L   + S+      +DN+ P+       + L+    ++  R  S     V   S ++  
Sbjct: 926  ELAAGSDSNERDSTKEDNVAPL------RFHLKYEADVLFTRSSSLSHYEVKPNSSLERY 979

Query: 789  EDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLL 831
            + +G P    F++  +  GL  +  +++ +  P    +G  LL
Sbjct: 980  DGIGPPFSCIFRIQNL--GLFPIHGMMMKITIPIATRSGNRLL 1020



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 18/45 (40%), Positives = 31/45 (68%)

Query: 981  ELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTR 1025
            E+ ++   ++ +W+++ +   GLLLL L++L LWK GFF+ AR R
Sbjct: 1131 EISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRR 1175


>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
          Length = 1181

 Score =  171 bits (434), Expect = 3e-42
 Identities = 217/896 (24%), Positives = 367/896 (40%), Gaps = 125/896 (13%)

Query: 190  DYLETGMCQLGTSGGFT-QNTVYF-GAPGAYNWKGNSYMIQRKE-----WDLSEYSYKDP 242
            D  +  M Q+G S  ++ QN +   GA GA+ W G   ++Q+       +    +     
Sbjct: 372  DNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGT--IVQKTSHGHLIFPKQAFDQILQ 429

Query: 243  EDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQ 302
            +   + Y+GY++     I   ++   V GAPR  + G + L S    G++   Q   G Q
Sbjct: 430  DRNHSSYLGYSVAA---ISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQ 486

Query: 303  VGAYFGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLL 361
            +G+YFGS +   D++ D   D LLVGAP Y    ++  G +Y+F  + G          L
Sbjct: 487  IGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGI---LGQHQFL 543

Query: 362  HGPSG---SAFGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYHSSSKGLLR--QPQ 414
             GP G   + FG ++A++ DIN DGF D+ VG+P E    G VYIY +  +G +R    Q
Sbjct: 544  EGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIY-NGHQGTIRTKYSQ 602

Query: 415  QVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINI-VHKTL 473
            +++  +      L  FG SL G  D++ +   D+ +G+    +V L ++ + ++ +  + 
Sbjct: 603  KILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG-QVVQLWSQSIADVAIEASF 661

Query: 474  VPRPAVLDPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAG 533
             P        L    + + ++LCF+        N +  I    TL+AD            
Sbjct: 662  TPEKI----TLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNITLDAD----------GF 707

Query: 534  SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDA 593
            S      G F     RC +  +++          I I     +   +  R  + L +   
Sbjct: 708  SSRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGT 767

Query: 594  YPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLL 653
             P L           + F K+CG D  C S+L +    +   Q++      S   ++L  
Sbjct: 768  SPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQ--PFIVSNQNKRLTF 825

Query: 654  SINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPP-----GACQ---ANETIFCELG 705
            S+ + N R      E A+   + +     L  +S   P       CQ   + +++ C++G
Sbjct: 826  SVTLKNKR------ESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVG 879

Query: 706  NP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLS--------TSSHQDNLWPMILTLLV 756
             P  KR Q++   I F+      + ++LQ Q  LS          +  DNL  + + LL 
Sbjct: 880  YPALKREQQVTFTINFD-----FNLQNLQNQASLSFQALSESQEENKADNLVNLKIPLLY 934

Query: 757  DYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVL 816
            D  +  + S   +  +    G V   S + + EDVG    +  +V   G   V + T+++
Sbjct: 935  DAEIHLTRSTNINFYEISSDGNV--PSIVHSFEDVGPKFIFSLKV-TTGSVPVSMATVII 991

Query: 817  GLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQ 876
             +  P        L+Y T +     G   C      INPL +                  
Sbjct: 992  HI--PQYTKEKNPLMYLTGVQTDKAGDISCNAD---INPLKI------------------ 1028

Query: 877  LDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVTN--VTVKARVW 934
                 GQ    V+   ++  +    L C T  A C  + C + D  +     V V  R+W
Sbjct: 1029 -----GQTSSSVSF-KSENFRHTKELNCRT--ASCSNVTCWLKDVHMKGEYFVNVTTRIW 1080

Query: 935  NSTFIEDYRDFDRVRVNGWATLFLRTSIPTIN-MENKTTWFSVDIDSELVEELPAEIELW 993
            N TF      F  V++   A   + T  P I  +E+ T    + I   +  +  AE+   
Sbjct: 1081 NGTFASS--TFQTVQLT--AAAEINTYNPEIYVIEDNTVTIPLMI---MKPDEKAEVPTG 1133

Query: 994  LVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQKAEMKSQPSETERLTD 1049
            +++ ++ AG+LLL  ++ +LWK GFFKR      YE      +M   P E +  T+
Sbjct: 1134 VIIGSIIAGILLLLALVAILWKLGFFKRK-----YE------KMTKNPDEIDETTE 1178



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 15/173 (8%)

Query: 4   GPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTE 63
           GP R   AP  +L  LAL      C + A+N+      +  +G     FGY+V   +Q  
Sbjct: 2   GPERTGAAPLPLLLVLALSQGILNCCL-AYNVGLPEAKIF-SGPSSEQFGYAV---QQFI 56

Query: 64  RQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGH--HIIED 121
             +   LL G+P     P+   NR G VY CP+      CE++N+       +   +  +
Sbjct: 57  NPKGNWLLVGSPWS-GFPE---NRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTN 112

Query: 122 MWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSS 174
           M LG+ +      G  L C   + Q       +Q    G C     D +L +S
Sbjct: 113 MSLGLILTRNMGTGGFLTCGPLWAQ----QCGNQYYTTGVCSDISPDFQLSAS 161


>gi|148728188 integrin, alpha E precursor [Homo sapiens]
          Length = 1179

 Score =  170 bits (431), Expect = 6e-42
 Identities = 162/593 (27%), Positives = 276/593 (46%), Gaps = 70/593 (11%)

Query: 190 DYLETGMCQLGTSGGFT-QNTVYFGAPGAYNWKGNSYMIQRKE-----WDLSEYSYKDPE 243
           D L   + Q+G S     +  V  GA GA++W G + +   +       + +  +  D E
Sbjct: 395 DALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAE 454

Query: 244 DQGNLYIGYTMQVGSFILHPK-NITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQ 302
                Y+GY + V    LH   +++ + GAPR++H GAVF L +E G +     VLEG Q
Sbjct: 455 AAQYSYLGYAVAV----LHKTCSLSYIAGAPRYKHHGAVFELQKE-GREASFLPVLEGEQ 509

Query: 303 VGAYFGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVF-MNQAGTSFPAHPSLL 360
           +G+YFGS +   D++ DG  D LLV AP+Y    EE  G +YV+ +++   SF     L 
Sbjct: 510 MGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEE--GRVYVYRLSEQDGSFSLARILS 567

Query: 361 LH-GPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--------LGKVYIYHSSSKGLLR 411
            H G + + FG ++A++GD++QD   D+A+GAP EG         G VYIY+    GL  
Sbjct: 568 GHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSA 627

Query: 412 QPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK 471
            P Q I    +  PGL  FG S++G  D+  +   D+ VG+L   +V  R+RPV+ +   
Sbjct: 628 SPSQRIRASTVA-PGLQYFGMSMAGGFDISGDGLADITVGTLGQAVV-FRSRPVVRL-KV 684

Query: 472 TLVPRPAVLDPALCTATSCVQVELCFAYNQ-SAGNPNYRRNITLAYTLEADRDRRPPRLR 530
           ++   P+ L          V V LCF  +  +  + +  R   L +TL+ D  ++  RL+
Sbjct: 685 SMAFTPSALPIGF---NGVVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQ 741

Query: 531 FAGSESAV-FHGFFSMPEMRCQKLELLLMDN---LRDKLRPIIISMNYSL--PLRMPDRP 584
            +   S +     +S     C+ L L+  +      D      + ++Y L  P    D P
Sbjct: 742 CSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDHP 801

Query: 585 RLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQY 644
           +         PIL++        ++ ++K C     C + LQ+ A  VS+Q+  +     
Sbjct: 802 Q---------PILDRYTEPFAIFQLPYEKACKNKLFCVAELQL-ATTVSQQELVVGL--- 848

Query: 645 SRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPGA----CQANETI 700
               ++L L+IN+TN      SGED++   + L  P  L L  ++ P +    C   + +
Sbjct: 849 ---TKELTLNINLTN------SGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPV 899

Query: 701 F------CELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNL 747
                  C +G+P  +     + + +++       R   + + ++ S+ + +L
Sbjct: 900 ASVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSL 952



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 36/116 (31%), Positives = 61/116 (52%), Gaps = 9/116 (7%)

Query: 926  NVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVD-IDSELVE 984
            NVTV A +      E  +D   +++ G  + F ++    +N EN  T  +V  +  E   
Sbjct: 1065 NVTVAAEISWDHSEELLKDVTELQILGEIS-FNKSLYEGLNAENHRTKITVVFLKDEKYH 1123

Query: 985  ELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQKAEMKSQ 1040
             LP      +++     GLL+L +I+++L+KCGFFKR   +   E+ R KA++KS+
Sbjct: 1124 SLP------IIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLESIR-KAQLKSE 1172


>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
          Length = 1153

 Score =  167 bits (422), Expect = 6e-41
 Identities = 210/871 (24%), Positives = 364/871 (41%), Gaps = 123/871 (14%)

Query: 193  ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGY 252
            E  M Q G S   T N       G+Y+W G  ++   KE        +   D  + Y+GY
Sbjct: 347  EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406

Query: 253  TMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIA 312
               +   IL  +  ++V GAPR++H+G V +  Q  G       V +G+Q+GAYFG+++ 
Sbjct: 407  AAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV-KGTQIGAYFGASLC 462

Query: 313  LADLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SA 368
              D++++G  DL L+GAP+Y+E+    GG + V     G         +L+G  G     
Sbjct: 463  SVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGR 520

Query: 369  FGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYH-SSSKGLLRQPQQVIHGEKLGLP 425
            FG ++  +GD+N D   D+A+GAP E    G VY++H +S  G+     Q I G KL  P
Sbjct: 521  FGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLS-P 579

Query: 426  GLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV---PRPAVLDP 482
             L  FG SLSG  D+  +   DL VG+   H++LLR++PV+ +  K ++   PR    + 
Sbjct: 580  RLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLRV--KAIMEFNPREVARNV 636

Query: 483  ALCT-----ATSCVQVELCFAYNQSAGNPNYRRNI--TLAYTLEADRDRRPPRLRFAGSE 535
              C           +V +C    +S  +      I   + Y L  D  R   R  F  ++
Sbjct: 637  FECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETK 696

Query: 536  SAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAY 594
            ++       +     C+ L+L L + + D + PI++ +N+SL +  P      LR     
Sbjct: 697  NSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL-VGTPLSAFGNLR----- 750

Query: 595  PILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLS 654
            P+L +           F+K CG DN C+ +L +  +F+S     +         R+  ++
Sbjct: 751  PVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG------GPREFNVT 804

Query: 655  INVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPG----------ACQ--------- 695
            + V N       GED++   +T   P  L    V              AC+         
Sbjct: 805  VTVRN------DGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 858

Query: 696  ANETIFCELGNP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH--QDNLWPMIL 752
            A ++  C + +P F  N  +   I F+V         L ++  +++ ++  + N     L
Sbjct: 859  ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQL 918

Query: 753  TLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLG 812
             L V Y +   + + +H + + +             E+    +++++QV  +G+  + + 
Sbjct: 919  ELPVKYAVY--MVVTSHGVSTKY-------LNFTASENTSRVMQHQYQVSNLGQRSLPIS 969

Query: 813  TLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQR 872
                             L++   + ++    W  RP       L+ T       PS    
Sbjct: 970  -----------------LVFLVPVRLNQTVIWD-RPQVTFSENLSSTCHTKERLPSHSD- 1010

Query: 873  RRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVT--NVTVK 930
                             LA  +KA    V+ C+   A C  ++C IP   +    N T+K
Sbjct: 1011 ----------------FLAELRKA---PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLK 1049

Query: 931  ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990
              +    +I+     + + +   A +    S+ T+ +  +  +     +++ VE      
Sbjct: 1050 GNLSFDWYIK--TSHNHLLIVSTAEILFNDSVFTL-LPGQGAFVRSQTETK-VEPFEVPN 1105

Query: 991  ELWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021
             L L++ +   GLLLL LI   L+K GFFKR
Sbjct: 1106 PLPLIVGSSVGGLLLLALITAALYKLGFFKR 1136


>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
          Length = 1152

 Score =  164 bits (414), Expect = 5e-40
 Identities = 210/871 (24%), Positives = 365/871 (41%), Gaps = 124/871 (14%)

Query: 193  ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGY 252
            E  M Q G S   T N       G+Y+W G  ++   KE        +   D  + Y+GY
Sbjct: 347  EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406

Query: 253  TMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIA 312
               +   IL  +  ++V GAPR++H+G V +  Q  G       V +G+Q+GAYFG+++ 
Sbjct: 407  AAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV-KGTQIGAYFGASLC 462

Query: 313  LADLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SA 368
              D++++G  DL L+GAP+Y+E+    GG + V     G +       +L+G  G     
Sbjct: 463  SVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRA-RWQCDAVLYGEQGQPWGR 519

Query: 369  FGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYH-SSSKGLLRQPQQVIHGEKLGLP 425
            FG ++  +GD+N D   D+A+GAP E    G VY++H +S  G+     Q I G KL  P
Sbjct: 520  FGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLS-P 578

Query: 426  GLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV---PRPAVLDP 482
             L  FG SLSG  D+  +   DL VG+   H++LLR++PV+ +  K ++   PR    + 
Sbjct: 579  RLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLRV--KAIMEFNPREVARNV 635

Query: 483  ALCT-----ATSCVQVELCFAYNQSAGNPNYRRNI--TLAYTLEADRDRRPPRLRFAGSE 535
              C           +V +C    +S  +      I   + Y L  D  R   R  F  ++
Sbjct: 636  FECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETK 695

Query: 536  SAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAY 594
            ++       +     C+ L+L L + + D + PI++ +N+SL +  P      LR     
Sbjct: 696  NSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL-VGTPLSAFGNLR----- 749

Query: 595  PILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLS 654
            P+L +           F+K CG DN C+ +L +  +F+S     +         R+  ++
Sbjct: 750  PVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG------GPREFNVT 803

Query: 655  INVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPG----------ACQ--------- 695
            + V N       GED++   +T   P  L    V              AC+         
Sbjct: 804  VTVRN------DGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 857

Query: 696  ANETIFCELGNP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH--QDNLWPMIL 752
            A ++  C + +P F  N  +   I F+V         L ++  +++ ++  + N     L
Sbjct: 858  ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQL 917

Query: 753  TLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLG 812
             L V Y +   + + +H + + +             E+    +++++QV  +G+  + + 
Sbjct: 918  ELPVKYAVY--MVVTSHGVSTKY-------LNFTASENTSRVMQHQYQVSNLGQRSLPIS 968

Query: 813  TLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQR 872
                             L++   + ++    W  RP       L+ T       PS    
Sbjct: 969  -----------------LVFLVPVRLNQTVIWD-RPQVTFSENLSSTCHTKERLPSHSD- 1009

Query: 873  RRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVT--NVTVK 930
                             LA  +KA    V+ C+   A C  ++C IP   +    N T+K
Sbjct: 1010 ----------------FLAELRKA---PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLK 1048

Query: 931  ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990
              +    +I+     + + +   A +    S+ T+ +  +  +     +++ VE      
Sbjct: 1049 GNLSFDWYIK--TSHNHLLIVSTAEILFNDSVFTL-LPGQGAFVRSQTETK-VEPFEVPN 1104

Query: 991  ELWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021
             L L++ +   GLLLL LI   L+K GFFKR
Sbjct: 1105 PLPLIVGSSVGGLLLLALITAALYKLGFFKR 1135


>gi|62548866 integrin, alpha D precursor [Homo sapiens]
          Length = 1161

 Score =  156 bits (395), Expect = 8e-38
 Identities = 139/516 (26%), Positives = 244/516 (47%), Gaps = 69/516 (13%)

Query: 196 MCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGYTMQ 255
           M Q G S   T + ++ GA G+++W G +++             ++  D  + Y+GY+ +
Sbjct: 350 MSQEGFSTALTMDGLFLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTE 409

Query: 256 VGSFILHPKNI-TIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALA 314
           +  +    K +  +V GAPR++H G   + +Q      R++  + G+Q+G+YFG+++   
Sbjct: 410 LALW----KGVQNLVLGAPRYQHTGKAVIFTQ-VSRQWRKKAEVTGTQIGSYFGASLCSV 464

Query: 315 DLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SAFG 370
           D+++DG  DL L+GAP+Y+E+    GG + V     G         +L G  G     FG
Sbjct: 465 DVDSDGSTDLILIGAPHYYEQTR--GGQVSVCPLPRG-RVQWQCDAVLRGEQGHPWGRFG 521

Query: 371 LSVASIGDINQDGFQDIAVGAP--FEGLGKVYIYHSSSK-GLLRQPQQVIHGEKLGLPGL 427
            ++  +GD+N+D   D+A+GAP   E  G VY++H +S+ G+     Q I   +L  P L
Sbjct: 522 AALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLS-PRL 580

Query: 428 ATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINI--------------VHKTL 473
             FG +LSG  D+ ++   DL VG+    ++LLR+ PV+ +              V++  
Sbjct: 581 QYFGQALSGGQDLTQDGLMDLAVGA-RGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCW 639

Query: 474 VPRPAVLDPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAG 533
             +P+ L+    T        +C    +S+ +       ++ + L  D  R   R  F  
Sbjct: 640 EEKPSALEAGDAT--------VCLTIQKSSLDQLGDIQSSVRFDLALDPGRLTSRAIFNE 691

Query: 534 SESAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSL---PLRMPD--RPRLG 587
           +++       ++   + C+ L+LLL D + D + PII+ +N+SL   P+  P   RP L 
Sbjct: 692 TKNPTLTRRKTLGLGIHCETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQNLRPVLA 751

Query: 588 LRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRD 647
           + S D +              + F+K CG D  CE +L +  +F        S LQ    
Sbjct: 752 VGSQDLFT-----------ASLPFEKNCGQDGLCEGDLGVTLSF--------SGLQTLTV 792

Query: 648 VRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL 683
              L L++ V    T   +GED++  +++L  P  L
Sbjct: 793 GSSLELNVIV----TVWNAGEDSYGTVVSLYYPAGL 824


>gi|34452173 integrin alpha X precursor [Homo sapiens]
          Length = 1163

 Score =  147 bits (370), Expect = 7e-35
 Identities = 124/465 (26%), Positives = 221/465 (47%), Gaps = 39/465 (8%)

Query: 187 SNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQG 246
           +++   E  M Q G S  FT +    GA G++ W G +++             ++  D  
Sbjct: 342 TSSSSFELEMAQEGFSAVFTPDGPVLGAVGSFTWSGGAFLYPPNMSPTFINMSQENVDMR 401

Query: 247 NLYIGYTMQVGSFILHPKNI-TIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGA 305
           + Y+GY+ ++  +    K + ++V GAPR++H G   + +Q      R +  + G+Q+G+
Sbjct: 402 DSYLGYSTELALW----KGVQSLVLGAPRYQHTGKAVIFTQ-VSRQWRMKAEVTGTQIGS 456

Query: 306 YFGSAIALADLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGP 364
           YFG+++   D+++DG  DL L+GAP+Y+E+    GG + V     G         +L+G 
Sbjct: 457 YFGASLCSVDVDSDGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGWR-RWWCDAVLYGE 513

Query: 365 SG---SAFGLSVASIGDINQDGFQDIAVGAP--FEGLGKVYIYHSSSKGLLRQPQQVIHG 419
            G     FG ++  +GD+N D   D+ +GAP   E  G VY++H    G+L       H 
Sbjct: 514 QGHPWGRFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFH----GVLGPSISPSHS 569

Query: 420 EKLGLPGLAT----FGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINI-VHKTLV 474
           +++    L++    FG +LSG  D+ ++   DL VG+    ++LLR RPV+ + V    +
Sbjct: 570 QRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGA-RGQVLLLRTRPVLWVGVSMQFI 628

Query: 475 PRPAVLDPALC-----TATSCVQVELCFAYNQSAGNPNYRRNITLAYTLE--ADRDRRPP 527
           P         C     +  + VQ  +C   ++ + N    R++  + TL+   D  R  P
Sbjct: 629 PAEIPRSAFECREQVVSEQTLVQSNICLYIDKRSKNLLGSRDLQSSVTLDLALDPGRLSP 688

Query: 528 RLRFAGSESAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRL 586
           R  F  +++        +  +  C+   LLL   + D + PI + +N++L      +P L
Sbjct: 689 RATFQETKNRSLSRVRVLGLKAHCENFNLLLPSCVEDSVTPITLRLNFTL----VGKPLL 744

Query: 587 GLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAF 631
             R+L   P+L           + F+K CG D+ C+ NL +  +F
Sbjct: 745 AFRNL--RPMLAADAQRYFTASLPFEKNCGADHICQDNLGISFSF 787



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 22/47 (46%), Positives = 26/47 (55%), Gaps = 5/47 (10%)

Query: 1002 GLLLLGLIILLLWKCGFFKRARTRALYEAKRQKA-----EMKSQPSE 1043
            GLLLL LI  +L+K GFFKR     + EA  Q A     +  S PSE
Sbjct: 1116 GLLLLALITAVLYKVGFFKRQYKEMMEEANGQIAPENGTQTPSPPSE 1162


>gi|29171717 glycosylphosphatidylinositol specific phospholipase D1
           isoform 1 precursor [Homo sapiens]
          Length = 840

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 55/195 (28%), Positives = 81/195 (41%), Gaps = 18/195 (9%)

Query: 273 PRHRHMGAVFLLSQEAGG--------DLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDL 324
           P H H+G V+L+     G        D    ++LEG Q    FGSA+A+ D N DG  DL
Sbjct: 408 PGHIHIGRVYLIYGNDLGLPPVDLDLDKEAHRILEGFQPSGRFGSALAVLDFNVDGVPDL 467

Query: 325 LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSGSAFGLSVASIGDINQDGF 384
            VGAP     +    GA+YV+         + P++ +                D+N D  
Sbjct: 468 AVGAPSVGSEQLTYKGAVYVYFGSKQGGMSSSPNITISCQDIYCNLGWTLLAADVNGDSE 527

Query: 385 QDIAVGAPF-------EGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQ 437
            D+ +G+PF       +G+   +    S     +   +  +    G    + FGYSL G 
Sbjct: 528 PDLVIGSPFAPGGGKQKGIVAAFYSGPSLSDKEKLNVEAANWTVRGEEDFSWFGYSLHG- 586

Query: 438 MDVDENFYPDLLVGS 452
           + VD      LLVGS
Sbjct: 587 VTVDNRTL--LLVGS 599



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 82/293 (27%), Positives = 126/293 (43%), Gaps = 42/293 (14%)

Query: 186 NSNTDYLETGMCQLGTSG-GFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPED 244
           ++N  +L + M + GTS     +N ++    G  N    S M +         S  +  D
Sbjct: 258 STNIYHLTSFMLENGTSDCNLPENPLFIACGGQQNHTQGSKMQKNDFHRNLTTSLTESVD 317

Query: 245 QGNLYI--GYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQ 302
           +   Y   G    V S+   P +++ +  A   R++  +F+     G  L ++ V   S 
Sbjct: 318 RNINYTERGVFFSVNSWT--PDSMSFIYKA-LERNIRTMFI----GGSQLSQKHV--SSP 368

Query: 303 VGAYF--------GSAIALADLNNDGWQDLLVGAPYYFERKE-EVGGAIYVFMNQAG--- 350
           + +YF        G A+  ADLN DG  DL+VGAP Y       +G    ++ N  G   
Sbjct: 369 LASYFLSFPYARLGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPP 428

Query: 351 ----TSFPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG------LGKVY 400
                   AH  L    PSG  FG ++A + D N DG  D+AVGAP  G       G VY
Sbjct: 429 VDLDLDKEAHRILEGFQPSG-RFGSALAVL-DFNVDGVPDLAVGAPSVGSEQLTYKGAVY 486

Query: 401 IYHSSSK-GLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGS 452
           +Y  S + G+   P   I  + +        G++L    DV+ +  PDL++GS
Sbjct: 487 VYFGSKQGGMSSSPNITISCQDI----YCNLGWTLLA-ADVNGDSEPDLVIGS 534


>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
          Length = 397

 Score = 35.0 bits (79), Expect = 0.37
 Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 12/106 (11%)

Query: 347 NQAGTSFPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSS 406
           + A  SFP  PSL   GP+   +G    S+G+  Q      A+G P   LG   + H   
Sbjct: 251 SDAEVSFPDEPSLAEMGPANGLYG----SLGEPTQ------ALGRPSGALGNFSLEHGGL 300

Query: 407 KGLLRQPQQVIHGEKLGLPGLATFGYSLSG-QMDVDENFYPDLLVG 451
            G   Q +++  G   G+P       SL G Q  +    YPD  +G
Sbjct: 301 AG-PEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLG 345


>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
          Length = 402

 Score = 35.0 bits (79), Expect = 0.37
 Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 12/106 (11%)

Query: 347 NQAGTSFPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSS 406
           + A  SFP  PSL   GP+   +G    S+G+  Q      A+G P   LG   + H   
Sbjct: 256 SDAEVSFPDEPSLAEMGPANGLYG----SLGEPTQ------ALGRPSGALGNFSLEHGGL 305

Query: 407 KGLLRQPQQVIHGEKLGLPGLATFGYSLSG-QMDVDENFYPDLLVG 451
            G   Q +++  G   G+P       SL G Q  +    YPD  +G
Sbjct: 306 AG-PEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLG 350


>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
            sapiens]
          Length = 462

 Score = 34.7 bits (78), Expect = 0.48
 Identities = 22/47 (46%), Positives = 26/47 (55%), Gaps = 5/47 (10%)

Query: 1002 GLLLLGLIILLLWKCGFFKRARTRALYEAKRQKA-----EMKSQPSE 1043
            GLLLL LI  +L+K GFFKR     + EA  Q A     +  S PSE
Sbjct: 415  GLLLLALITAVLYKVGFFKRQYKEMMEEANGQIAPENGTQTPSPPSE 461


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,925,595
Number of Sequences: 37866
Number of extensions: 2147182
Number of successful extensions: 5246
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 4869
Number of HSP's gapped (non-prelim): 67
length of query: 1051
length of database: 18,247,518
effective HSP length: 113
effective length of query: 938
effective length of database: 13,968,660
effective search space: 13102603080
effective search space used: 13102603080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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