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Search of human proteins with 4504609
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504609 insulin-like growth factor 2 isoform 1 precursor
[Homo sapiens]
(180 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504609 insulin-like growth factor 2 isoform 1 precursor [Hom... 373 e-104
gi|108796063 insulin-like growth factor 2 isoform 1 precursor [H... 373 e-104
gi|189083846 insulin-like growth factor 2 isoform 2 [Homo sapiens] 373 e-104
gi|11024682 insulin-like growth factor 1 isoform 4 preproprotein... 94 8e-20
gi|163659903 insulin-like growth factor 1 isoform 3 preproprotei... 94 8e-20
gi|163659901 insulin-like growth factor 1 isoform 2 preproprotei... 94 8e-20
gi|163659899 insulin-like growth factor 1 isoform 1 preproprotei... 94 8e-20
gi|4557671 proinsulin precursor [Homo sapiens] 52 2e-07
gi|109148522 insulin- insulin-like growth factor 2 [Homo sapiens] 39 0.003
gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 30 1.5
gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 30 1.5
gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 30 1.5
gi|71725371 solute carrier family 10 (sodium/bile acid cotranspo... 29 2.5
gi|47419930 chondroitin sulfate proteoglycan 4 [Homo sapiens] 28 4.3
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens] 28 4.3
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 28 5.6
gi|169167740 PREDICTED: hypothetical protein [Homo sapiens] 27 9.5
gi|239750488 PREDICTED: similar to CNOT4 protein, partial [Homo ... 27 9.5
gi|113416994 PREDICTED: hypothetical protein [Homo sapiens] 27 9.5
gi|239744787 PREDICTED: similar to CNOT4 protein, partial [Homo ... 27 9.5
gi|113416470 PREDICTED: hypothetical protein [Homo sapiens] 27 9.5
gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens] 27 9.5
gi|157426856 armadillo repeat containing 5 isoform a [Homo sapiens] 27 9.5
>gi|4504609 insulin-like growth factor 2 isoform 1 precursor [Homo
sapiens]
Length = 180
Score = 373 bits (957), Expect = e-104
Identities = 180/180 (100%), Positives = 180/180 (100%)
Query: 1 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 60
MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
Sbjct: 1 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 60
Query: 61 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 120
RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
Sbjct: 61 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 120
Query: 121 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 180
QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Sbjct: 121 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 180
>gi|108796063 insulin-like growth factor 2 isoform 1 precursor [Homo
sapiens]
Length = 180
Score = 373 bits (957), Expect = e-104
Identities = 180/180 (100%), Positives = 180/180 (100%)
Query: 1 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 60
MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
Sbjct: 1 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 60
Query: 61 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 120
RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
Sbjct: 61 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 120
Query: 121 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 180
QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Sbjct: 121 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 180
>gi|189083846 insulin-like growth factor 2 isoform 2 [Homo sapiens]
Length = 236
Score = 373 bits (957), Expect = e-104
Identities = 180/180 (100%), Positives = 180/180 (100%)
Query: 1 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 60
MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
Sbjct: 57 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 116
Query: 61 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 120
RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
Sbjct: 117 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 176
Query: 121 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 180
QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Sbjct: 177 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 236
>gi|11024682 insulin-like growth factor 1 isoform 4 preproprotein
[Homo sapiens]
Length = 153
Score = 93.6 bits (231), Expect = 8e-20
Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)
Query: 10 LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 65
L LLTF + A+ ETLCG ELVD LQFVCGDRGFYF++P S R G
Sbjct: 37 LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 90
Query: 66 IVEECCFRSCDLALLETYCA--TPAKSERDV 94
IV+ECCFRSCDL LE YCA PAKS R V
Sbjct: 91 IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 121
>gi|163659903 insulin-like growth factor 1 isoform 3 preproprotein
[Homo sapiens]
Length = 195
Score = 93.6 bits (231), Expect = 8e-20
Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)
Query: 10 LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 65
L LLTF + A+ ETLCG ELVD LQFVCGDRGFYF++P S R G
Sbjct: 37 LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 90
Query: 66 IVEECCFRSCDLALLETYCA--TPAKSERDV 94
IV+ECCFRSCDL LE YCA PAKS R V
Sbjct: 91 IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 121
>gi|163659901 insulin-like growth factor 1 isoform 2 preproprotein
[Homo sapiens]
Length = 137
Score = 93.6 bits (231), Expect = 8e-20
Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)
Query: 10 LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 65
L LLTF + A+ ETLCG ELVD LQFVCGDRGFYF++P S R G
Sbjct: 21 LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 74
Query: 66 IVEECCFRSCDLALLETYCA--TPAKSERDV 94
IV+ECCFRSCDL LE YCA PAKS R V
Sbjct: 75 IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 105
>gi|163659899 insulin-like growth factor 1 isoform 1 preproprotein
[Homo sapiens]
Length = 158
Score = 93.6 bits (231), Expect = 8e-20
Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)
Query: 10 LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 65
L LLTF + A+ ETLCG ELVD LQFVCGDRGFYF++P S R G
Sbjct: 37 LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 90
Query: 66 IVEECCFRSCDLALLETYCA--TPAKSERDV 94
IV+ECCFRSCDL LE YCA PAKS R V
Sbjct: 91 IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 121
>gi|4557671 proinsulin precursor [Homo sapiens]
Length = 110
Score = 52.4 bits (124), Expect = 2e-07
Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 27/103 (26%)
Query: 9 MLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRV--------- 59
+L LL LA AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 7 LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQV 66
Query: 60 ------------------SRRSRGIVEECCFRSCDLALLETYC 84
S + RGIVE+CC C L LE YC
Sbjct: 67 ELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
>gi|109148522 insulin- insulin-like growth factor 2 [Homo sapiens]
Length = 200
Score = 38.5 bits (88), Expect = 0.003
Identities = 20/50 (40%), Positives = 28/50 (56%)
Query: 9 MLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR 58
+L LL LA AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 7 LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRR 56
>gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 29.6 bits (65), Expect = 1.5
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 4/46 (8%)
Query: 128 RGLPALLRARRGH----VLAKELEAFREAKRHRPLIALPTQDPAHG 169
RG PAL R GH + +K L+A + HR L T+ P HG
Sbjct: 1666 RGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHG 1711
>gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 29.6 bits (65), Expect = 1.5
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 4/46 (8%)
Query: 128 RGLPALLRARRGH----VLAKELEAFREAKRHRPLIALPTQDPAHG 169
RG PAL R GH + +K L+A + HR L T+ P HG
Sbjct: 1666 RGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHG 1711
>gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 29.6 bits (65), Expect = 1.5
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 4/46 (8%)
Query: 128 RGLPALLRARRGH----VLAKELEAFREAKRHRPLIALPTQDPAHG 169
RG PAL R GH + +K L+A + HR L T+ P HG
Sbjct: 1666 RGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHG 1711
>gi|71725371 solute carrier family 10 (sodium/bile acid
cotransporter family), member 7 isoform b [Homo sapiens]
Length = 340
Score = 28.9 bits (63), Expect = 2.5
Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 1 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQ--FVCGDRGFYFSRP 55
+GIPM K + L+ S + Y P++ L G LV T++ V +G +RP
Sbjct: 282 LGIPMLKIVFAGHEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRP 338
>gi|47419930 chondroitin sulfate proteoglycan 4 [Homo sapiens]
Length = 2322
Score = 28.1 bits (61), Expect = 4.3
Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 3/46 (6%)
Query: 133 LLRARRGHVLAKELEAFREAKRHR--PLIALPTQDPAHGGAP-PEM 175
+L A+ + LA + E FR+ + + PL A+P Q P GG P PE+
Sbjct: 2259 VLTAKPRNGLAGDTETFRKVEPGQAIPLTAVPGQGPPPGGQPDPEL 2304
>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
Length = 268
Score = 28.1 bits (61), Expect = 4.3
Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 7/80 (8%)
Query: 51 YFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPV 110
YF+ S SR G+ CC + ++ T C A+ + +V + Y
Sbjct: 167 YFNCTDSNASRERCGVPFSCCTKDPAEDVINTQCGYDARQKPEVDQQIVI-------YTK 219
Query: 111 GKFFQYDTWKQSTQRLRRGL 130
G Q++ W Q + G+
Sbjct: 220 GCVPQFEKWLQDNLTIVAGI 239
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 27.7 bits (60), Expect = 5.6
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 8/67 (11%)
Query: 120 KQSTQRLRRGLPALLRARRGHVLAKELEAFREAKR-------HRPLIALPTQDPAHGGAP 172
++ + + R+ LPA RAR A EL +A+ HRP P+ P H P
Sbjct: 433 RERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGH-TLP 491
Query: 173 PEMASNR 179
P+ S R
Sbjct: 492 PKPPSPR 498
>gi|169167740 PREDICTED: hypothetical protein [Homo sapiens]
Length = 302
Score = 26.9 bits (58), Expect = 9.5
Identities = 14/44 (31%), Positives = 20/44 (45%)
Query: 89 KSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPA 132
++ D P P + PR+P + WK S + RGLPA
Sbjct: 111 EARNDHRPPGRAPPRHAPRFPRPRMRFPQAWKASRAKEPRGLPA 154
>gi|239750488 PREDICTED: similar to CNOT4 protein, partial [Homo
sapiens]
Length = 318
Score = 26.9 bits (58), Expect = 9.5
Identities = 12/25 (48%), Positives = 15/25 (60%)
Query: 86 TPAKSERDVSTPPTVLPDNFPRYPV 110
+P S RD +PPT LP + P PV
Sbjct: 154 SPTTSNRDRPSPPTGLPKSSPVIPV 178
>gi|113416994 PREDICTED: hypothetical protein [Homo sapiens]
Length = 302
Score = 26.9 bits (58), Expect = 9.5
Identities = 14/44 (31%), Positives = 20/44 (45%)
Query: 89 KSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPA 132
++ D P P + PR+P + WK S + RGLPA
Sbjct: 111 EARNDHRPPGRAPPRHAPRFPRPRMRFPQAWKASRAKEPRGLPA 154
>gi|239744787 PREDICTED: similar to CNOT4 protein, partial [Homo
sapiens]
Length = 318
Score = 26.9 bits (58), Expect = 9.5
Identities = 12/25 (48%), Positives = 15/25 (60%)
Query: 86 TPAKSERDVSTPPTVLPDNFPRYPV 110
+P S RD +PPT LP + P PV
Sbjct: 154 SPTTSNRDRPSPPTGLPKSSPVIPV 178
>gi|113416470 PREDICTED: hypothetical protein [Homo sapiens]
Length = 302
Score = 26.9 bits (58), Expect = 9.5
Identities = 14/44 (31%), Positives = 20/44 (45%)
Query: 89 KSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPA 132
++ D P P + PR+P + WK S + RGLPA
Sbjct: 111 EARNDHRPPGRAPPRHAPRFPRPRMRFPQAWKASRAKEPRGLPA 154
>gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens]
Length = 725
Score = 26.9 bits (58), Expect = 9.5
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 132 ALLRARRGHVLAKE-LEAFREAKRHRPLIALPTQDPAHGGAPPE 174
ALL R H+ A +E FR RPL+AL + A G AP +
Sbjct: 43 ALLALRTRHIKAAGGIERFRARGGLRPLLALLRRAAAAGSAPSQ 86
>gi|157426856 armadillo repeat containing 5 isoform a [Homo sapiens]
Length = 935
Score = 26.9 bits (58), Expect = 9.5
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 132 ALLRARRGHVLAKE-LEAFREAKRHRPLIALPTQDPAHGGAPPE 174
ALL R H+ A +E FR RPL+AL + A G AP +
Sbjct: 43 ALLALRTRHIKAAGGIERFRARGGLRPLLALLRRAAAAGSAPSQ 86
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,785,672
Number of Sequences: 37866
Number of extensions: 348451
Number of successful extensions: 1040
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1018
Number of HSP's gapped (non-prelim): 24
length of query: 180
length of database: 18,247,518
effective HSP length: 96
effective length of query: 84
effective length of database: 14,612,382
effective search space: 1227440088
effective search space used: 1227440088
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.