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Search of human proteins with 4504507
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
(373 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 757 0.0
gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens] 714 0.0
gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s... 246 2e-65
gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 125 8e-29
gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 125 8e-29
gi|116268111 short chain dehydrogenase/reductase family 42E, mem... 122 5e-28
gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo ... 119 6e-27
gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family pr... 117 2e-26
gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo ... 117 2e-26
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s... 105 9e-23
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap... 105 9e-23
gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens] 63 4e-10
gi|56118217 UDP-galactose-4-epimerase [Homo sapiens] 37 0.022
gi|56237023 UDP-galactose-4-epimerase [Homo sapiens] 37 0.022
gi|189083684 UDP-galactose-4-epimerase [Homo sapiens] 37 0.022
gi|31542658 fatty acyl CoA reductase 2 [Homo sapiens] 37 0.037
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens] 35 0.083
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec... 35 0.083
gi|47419930 chondroitin sulfate proteoglycan 4 [Homo sapiens] 30 2.7
gi|24308324 fatty acyl CoA reductase 1 [Homo sapiens] 30 3.5
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens] 29 7.8
>gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 373
Score = 757 bits (1954), Expect = 0.0
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLE 60
MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLE
Sbjct: 1 MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLE 60
Query: 61 GDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVF 120
GDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVF
Sbjct: 61 GDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVF 120
Query: 121 IYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTL 180
IYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTL
Sbjct: 121 IYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTL 180
Query: 181 YTCALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL 240
YTCALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL
Sbjct: 181 YTCALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL 240
Query: 241 QDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEI 300
QDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEI
Sbjct: 241 QDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEI 300
Query: 301 VSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSL 360
VSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSL
Sbjct: 301 VSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSL 360
Query: 361 VDRHKETLKSKTQ 373
VDRHKETLKSKTQ
Sbjct: 361 VDRHKETLKSKTQ 373
>gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]
Length = 372
Score = 714 bits (1843), Expect = 0.0
Identities = 348/371 (93%), Positives = 359/371 (96%)
Query: 3 GWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGD 62
GWSCLVTGAGG LGQRI+RLLV+EKELKEIR LDKAF PELREEFSKLQN+TKLTVLEGD
Sbjct: 2 GWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGD 61
Query: 63 ILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIY 122
ILDEPFLKRACQDVSV+IHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIY
Sbjct: 62 ILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIY 121
Query: 123 TSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYT 182
TSSIEVAGPNSYKEIIQNGHEEEPLENTWP PYP+SKKLAEKAVLAANGWNLKNG TLYT
Sbjct: 122 TSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLYT 181
Query: 183 CALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALQD 242
CALRP YIYGEG FLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL+D
Sbjct: 182 CALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALRD 241
Query: 243 PKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEIVS 302
PKKAPS+RGQFYYISDDTPHQSYDNLNY LSKEFGLRLDSRWS PL+LMYWIGFLLE+VS
Sbjct: 242 PKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVVS 301
Query: 303 FLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVD 362
FLL PIY+Y+PPFNRH VTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVD
Sbjct: 302 FLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVD 361
Query: 363 RHKETLKSKTQ 373
RHKETLKSKTQ
Sbjct: 362 RHKETLKSKTQ 372
>gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform a [Homo sapiens]
Length = 369
Score = 246 bits (628), Expect = 2e-65
Identities = 139/354 (39%), Positives = 207/354 (58%), Gaps = 8/354 (2%)
Query: 7 LVTGAGGFLGQRIIRLLV-KEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILD 65
LVTG GFLG+ ++R+L+ +E L E+RV D+ GP L E + ++T ++GD+
Sbjct: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKT---GPVRVTAIQGDVTQ 69
Query: 66 EPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSS 125
+ A V+IHTA ++DVFG ++I VNV+GT+ ++EACVQ +YTSS
Sbjct: 70 AHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSS 129
Query: 126 IEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTCAL 185
+EV GPN+ G+E+ P E PYP SK LAE VL ANG ++ G L TCAL
Sbjct: 130 MEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCAL 189
Query: 186 RPMYIYGEGSRFLSASINEALNNNG-ILSSVGKFSTVNPVYVGNVAWAHILALRALQDPK 244
RP IYGEG + + + L G + ++ VYVGNVAW H+LA R L+ +
Sbjct: 190 RPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVLAARELE--Q 247
Query: 245 KAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRL-DSRWSFPLSLMYWIGFLLEIVSF 303
+A + GQ Y+ D +P++SY++ N GLRL +R P L+ ++ L ++ +
Sbjct: 248 RATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAALNALLQW 307
Query: 304 LLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWV 357
LLRP+ Y P N + + ++N+ FT S KAQR Y+PL+SWE+++ +T+ WV
Sbjct: 308 LLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTILWV 361
>gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform b [Homo sapiens]
Length = 196
Score = 125 bits (313), Expect = 8e-29
Identities = 70/166 (42%), Positives = 99/166 (59%), Gaps = 4/166 (2%)
Query: 7 LVTGAGGFLGQRIIRLLV-KEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILD 65
LVTG GFLG+ ++R+L+ +E L E+RV D+ GP L E + ++T ++GD+
Sbjct: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKT---GPVRVTAIQGDVTQ 69
Query: 66 EPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSS 125
+ A V+IHTA ++DVFG ++I VNV+GT+ ++EACVQ +YTSS
Sbjct: 70 AHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSS 129
Query: 126 IEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANG 171
+EV GPN+ G+E+ P E PYP SK LAE VL ANG
Sbjct: 130 MEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANG 175
>gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform b [Homo sapiens]
Length = 196
Score = 125 bits (313), Expect = 8e-29
Identities = 70/166 (42%), Positives = 99/166 (59%), Gaps = 4/166 (2%)
Query: 7 LVTGAGGFLGQRIIRLLV-KEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILD 65
LVTG GFLG+ ++R+L+ +E L E+RV D+ GP L E + ++T ++GD+
Sbjct: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKT---GPVRVTAIQGDVTQ 69
Query: 66 EPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSS 125
+ A V+IHTA ++DVFG ++I VNV+GT+ ++EACVQ +YTSS
Sbjct: 70 AHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSS 129
Query: 126 IEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANG 171
+EV GPN+ G+E+ P E PYP SK LAE VL ANG
Sbjct: 130 MEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANG 175
>gi|116268111 short chain dehydrogenase/reductase family 42E, member
1 [Homo sapiens]
Length = 393
Score = 122 bits (306), Expect = 5e-28
Identities = 115/364 (31%), Positives = 171/364 (46%), Gaps = 36/364 (9%)
Query: 5 SCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDIL 64
S L+TG G+ G R+ L + + + D + + E K ++GDI
Sbjct: 10 SVLITGGSGYFGFRLGCAL--NQNGVHVILFDISSPAQTIPEGIKF--------IQGDIR 59
Query: 65 DEPFLKRACQDVSVIIHTACIIDV--FGVTHRES-----IMNVNVKGTQLLLEACVQASV 117
+++A QD V C+ + +G++ RE I VNV+GT +L+ C + V
Sbjct: 60 HLSDVEKAFQDADV----TCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRV 115
Query: 118 PVFIYTSSIEVAGPNSYKEIIQNGHEEEPLE--NTWPAPYPHSKKLAEKAVLAANGWNLK 175
P +YTS+ V ++I+NG E P + P Y +K +AE+ VL AN L
Sbjct: 116 PRLVYTSTFNVIFGG---QVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLD 172
Query: 176 NG-GTLYTCALRPMYIYGEGSRFLSASINEALNNNGILSSV--GKFSTVNPVYVGNVAWA 232
G G L TCALRP IYG G + I + G+ V S V V+V N+ A
Sbjct: 173 RGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEK-GLFKFVYGDPRSLVEFVHVDNLVQA 231
Query: 233 HILALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMY 292
HILA AL+ K GQ Y+ISD P +++ L + G S PL+L+Y
Sbjct: 232 HILASEALR-ADKGHIASGQPYFISDGRPVNNFEFFR-PLVEGLGYTFPST-RLPLTLVY 288
Query: 293 WIGFLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQK 352
FL E+V F+L +Y ++P R V + FS +KA+++L YK + Q+
Sbjct: 289 CFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK---AQPFDLQE 345
Query: 353 TVEW 356
VEW
Sbjct: 346 AVEW 349
>gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo
sapiens]
Length = 422
Score = 119 bits (297), Expect = 6e-27
Identities = 109/347 (31%), Positives = 159/347 (45%), Gaps = 33/347 (9%)
Query: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILDE 66
LVTG GG+LG + L K + +LD+ R +L +TK ++ D+ DE
Sbjct: 37 LVTGGGGYLGFSLGSHLAKSGT--SVILLDR------RRPQWELSPETKF--IQADVRDE 86
Query: 67 PFLKRACQDVSVIIHTACIIDVFGVT-----HRESIMNVNVKGTQLLLEACVQASVPVFI 121
L RA + V + H A +G++ +E I ++NV GT+L+++ CV+ VP I
Sbjct: 87 EALYRAFEGVDCVFHVAS----YGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLI 142
Query: 122 YTSSIEVAGPNSYKEIIQNGHEEE----PLENTWPAPYPHSKKLAEKAVLAANGWNLKNG 177
YTS++ VA + I+ G E+ PL+ Y +K +A++ L ANG L G
Sbjct: 143 YTSTVNVAFGG---KPIEQGDEDSVPYFPLDEHVDH-YSRTKAIADQLTLMANGMPLPGG 198
Query: 178 GTLYTCALRPMYIYG-EGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILA 236
GTL TC LRP IYG E R L + + +N V+V N+ AH+LA
Sbjct: 199 GTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLA 258
Query: 237 LRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRW-SFPLSLMYWIG 295
AL K + GQ YYI+D ++ + K L W P S +Y
Sbjct: 259 AEALTTAKGYVA-SGQAYYINDGESVNLFEWMAPLFEK---LGYSQPWIQVPTSWVYLTA 314
Query: 296 FLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKP 342
++E + LRPI + P R V TF KA+ L Y P
Sbjct: 315 AVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361
>gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family
protein ENSP00000330812 [Homo sapiens]
Length = 422
Score = 117 bits (292), Expect = 2e-26
Identities = 108/347 (31%), Positives = 158/347 (45%), Gaps = 33/347 (9%)
Query: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILDE 66
LVTG GG+LG + L K + +LD+ R +L +TK ++ D+ DE
Sbjct: 37 LVTGGGGYLGFSLGSHLAKSGT--SVILLDR------RRPQWELSPETKF--IQADVRDE 86
Query: 67 PFLKRACQDVSVIIHTACIIDVFGVT-----HRESIMNVNVKGTQLLLEACVQASVPVFI 121
L A + V + H A +G++ +E I ++NV GT+L+++ CV+ VP I
Sbjct: 87 EALYHAFEGVDCVFHVAS----YGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLI 142
Query: 122 YTSSIEVAGPNSYKEIIQNGHEEE----PLENTWPAPYPHSKKLAEKAVLAANGWNLKNG 177
YTS++ VA + I+ G E+ PL+ Y +K +A++ L ANG L G
Sbjct: 143 YTSTVNVAFGG---KPIEQGDEDSVPYFPLDEHVDH-YSRTKAIADQLTLMANGMPLPGG 198
Query: 178 GTLYTCALRPMYIYG-EGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILA 236
GTL TC LRP IYG E R L + + +N V+V N+ AH+LA
Sbjct: 199 GTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLA 258
Query: 237 LRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRW-SFPLSLMYWIG 295
AL K + GQ YYI+D ++ + K L W P S +Y
Sbjct: 259 AEALTTAKGYVA-SGQAYYINDGESVNLFEWMAPLFEK---LGYSQPWIQVPTSWVYLTA 314
Query: 296 FLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKP 342
++E + LRPI + P R V TF KA+ L Y P
Sbjct: 315 AVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361
>gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo
sapiens]
Length = 422
Score = 117 bits (292), Expect = 2e-26
Identities = 108/347 (31%), Positives = 158/347 (45%), Gaps = 33/347 (9%)
Query: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILDE 66
LVTG GG+LG + L K + +LD+ R +L +TK ++ D+ DE
Sbjct: 37 LVTGGGGYLGFSLGSHLAKSGT--SVILLDR------RRPQWELSPETKF--IQADVRDE 86
Query: 67 PFLKRACQDVSVIIHTACIIDVFGVT-----HRESIMNVNVKGTQLLLEACVQASVPVFI 121
L A + V + H A +G++ +E I ++NV GT+L+++ CV+ VP I
Sbjct: 87 EALYHAFEGVDCVFHVAS----YGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLI 142
Query: 122 YTSSIEVAGPNSYKEIIQNGHEEE----PLENTWPAPYPHSKKLAEKAVLAANGWNLKNG 177
YTS++ VA + I+ G E+ PL+ Y +K +A++ L ANG L G
Sbjct: 143 YTSTVNVAFGG---KPIEQGDEDSVPYFPLDEHVDH-YSRTKAIADQLTLMANGMPLPGG 198
Query: 178 GTLYTCALRPMYIYG-EGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILA 236
GTL TC LRP IYG E R L + + +N V+V N+ AH+LA
Sbjct: 199 GTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLA 258
Query: 237 LRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRW-SFPLSLMYWIG 295
AL K + GQ YYI+D ++ + K L W P S +Y
Sbjct: 259 AEALTTAKGYVA-SGQAYYINDGESVNLFEWMAPLFEK---LGYSQPWIQVPTSWVYLTA 314
Query: 296 FLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKP 342
++E + LRPI + P R V TF KA+ L Y P
Sbjct: 315 AVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361
>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 105 bits (261), Expect = 9e-23
Identities = 94/354 (26%), Positives = 165/354 (46%), Gaps = 33/354 (9%)
Query: 6 CLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAF-GPELREEFSKLQNKTKLTVLEGDIL 64
C V G GFLGQ ++ L+ + + + F P++R GD+
Sbjct: 40 CTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVR-------------FFLGDLC 86
Query: 65 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124
L A + V+ + H C ++E VN GT+ ++E C +A V I TS
Sbjct: 87 SRQDLYPALKGVNTVFH--CASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTS 144
Query: 125 SIEVAGPNSYKEI-IQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTC 183
S V ++ + I+NG E+ P Y +K L E+AVL AN KN T
Sbjct: 145 SASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE-KN---FLTT 196
Query: 184 ALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFST-VNPVYVGNVAWAHILALRALQD 242
A+RP I+G L + EA N + +G V+ +V NV HILA L
Sbjct: 197 AIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLS- 255
Query: 243 PKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDS-RWSFPLSLMYWIGFLLEIV 301
+ ++ G+ ++I++D P + L+ L+ GL ++ ++ P + Y++ LL ++
Sbjct: 256 --RDSTLGGKAFHITNDEPIPFWTFLSRILT---GLNYEAPKYHIPYWVAYYLALLLSLL 310
Query: 302 SFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVE 355
++ P+ +P F V L+ + +S ++A++ + Y+PL + ++A ++TV+
Sbjct: 311 VMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQ 364
>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 105 bits (261), Expect = 9e-23
Identities = 94/354 (26%), Positives = 165/354 (46%), Gaps = 33/354 (9%)
Query: 6 CLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAF-GPELREEFSKLQNKTKLTVLEGDIL 64
C V G GFLGQ ++ L+ + + + F P++R GD+
Sbjct: 40 CTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVR-------------FFLGDLC 86
Query: 65 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124
L A + V+ + H C ++E VN GT+ ++E C +A V I TS
Sbjct: 87 SRQDLYPALKGVNTVFH--CASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTS 144
Query: 125 SIEVAGPNSYKEI-IQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTC 183
S V ++ + I+NG E+ P Y +K L E+AVL AN KN T
Sbjct: 145 SASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE-KN---FLTT 196
Query: 184 ALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFST-VNPVYVGNVAWAHILALRALQD 242
A+RP I+G L + EA N + +G V+ +V NV HILA L
Sbjct: 197 AIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLS- 255
Query: 243 PKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDS-RWSFPLSLMYWIGFLLEIV 301
+ ++ G+ ++I++D P + L+ L+ GL ++ ++ P + Y++ LL ++
Sbjct: 256 --RDSTLGGKAFHITNDEPIPFWTFLSRILT---GLNYEAPKYHIPYWVAYYLALLLSLL 310
Query: 302 SFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVE 355
++ P+ +P F V L+ + +S ++A++ + Y+PL + ++A ++TV+
Sbjct: 311 VMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQ 364
>gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]
Length = 350
Score = 63.2 bits (152), Expect = 4e-10
Identities = 86/356 (24%), Positives = 136/356 (38%), Gaps = 52/356 (14%)
Query: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILDE 66
LVTG GF+ +I LV++ I LDK + + NK ++GDI D
Sbjct: 21 LVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGDICDS 80
Query: 67 PFLKR--ACQDVSVIIHTACIIDV-FGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYT 123
F+K + + +++H A V VNV GT +L+ A +A V FIY
Sbjct: 81 HFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEKFIYV 140
Query: 124 SSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTC 183
S+ EV G + KE E P + T PY SK AE + W + T
Sbjct: 141 STDEVYGGSLDKEF----DESSPKQPT--NPYASSKAAAE--CFVQSYWEQYKFPVVIT- 191
Query: 184 ALRPMYIYGE---GSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL 240
R +YG + + I+ +N T N +Y +V A + L+
Sbjct: 192 --RSSNVYGPHQYPEKVIPKFISLLQHNRKCCIHGSGLQTRNFLYATDVVEAFLTVLK-- 247
Query: 241 QDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEI 300
K P G+ Y I +++ L+KE ++L + + W+ ++ +
Sbjct: 248 ---KGKP---GEIYNIG-----TNFEMSVVQLAKEL-IQLIKETNSESEMENWVDYVND- 294
Query: 301 VSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEW 356
RP R P + L ++P W+E +KT+EW
Sbjct: 295 -----RPTNDMRYPMKSEKI---------------HGLGWRPKVPWKEGIKKTIEW 330
>gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 37.4 bits (85), Expect = 0.022
Identities = 50/173 (28%), Positives = 71/173 (41%), Gaps = 23/173 (13%)
Query: 7 LVTGAGGFLGQRIIRLLVKEKELKE-IRVLDKAF--GPELREEFSKLQNKTKLTVL--EG 61
LVTG G++G + L++ L I AF G L E ++Q T +V E
Sbjct: 6 LVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEM 65
Query: 62 DILDEPFLKRACQDVS--VIIHTACIIDVFGVTHRE-SIMNVNVKGTQLLLEACVQASVP 118
DILD+ L+R + S +IH A + V + VN+ GT LLE V
Sbjct: 66 DILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVK 125
Query: 119 VFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPA-----PYPHSKKLAEKAV 166
+++SS V G Y PL+ P PY SK E+ +
Sbjct: 126 NLVFSSSATVYGNPQYL----------PLDEAHPTGGCTNPYGKSKFFIEEMI 168
>gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 37.4 bits (85), Expect = 0.022
Identities = 50/173 (28%), Positives = 71/173 (41%), Gaps = 23/173 (13%)
Query: 7 LVTGAGGFLGQRIIRLLVKEKELKE-IRVLDKAF--GPELREEFSKLQNKTKLTVL--EG 61
LVTG G++G + L++ L I AF G L E ++Q T +V E
Sbjct: 6 LVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEM 65
Query: 62 DILDEPFLKRACQDVS--VIIHTACIIDVFGVTHRE-SIMNVNVKGTQLLLEACVQASVP 118
DILD+ L+R + S +IH A + V + VN+ GT LLE V
Sbjct: 66 DILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVK 125
Query: 119 VFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPA-----PYPHSKKLAEKAV 166
+++SS V G Y PL+ P PY SK E+ +
Sbjct: 126 NLVFSSSATVYGNPQYL----------PLDEAHPTGGCTNPYGKSKFFIEEMI 168
>gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 37.4 bits (85), Expect = 0.022
Identities = 50/173 (28%), Positives = 71/173 (41%), Gaps = 23/173 (13%)
Query: 7 LVTGAGGFLGQRIIRLLVKEKELKE-IRVLDKAF--GPELREEFSKLQNKTKLTVL--EG 61
LVTG G++G + L++ L I AF G L E ++Q T +V E
Sbjct: 6 LVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEM 65
Query: 62 DILDEPFLKRACQDVS--VIIHTACIIDVFGVTHRE-SIMNVNVKGTQLLLEACVQASVP 118
DILD+ L+R + S +IH A + V + VN+ GT LLE V
Sbjct: 66 DILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVK 125
Query: 119 VFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPA-----PYPHSKKLAEKAV 166
+++SS V G Y PL+ P PY SK E+ +
Sbjct: 126 NLVFSSSATVYGNPQYL----------PLDEAHPTGGCTNPYGKSKFFIEEMI 168
>gi|31542658 fatty acyl CoA reductase 2 [Homo sapiens]
Length = 515
Score = 36.6 bits (83), Expect = 0.037
Identities = 58/259 (22%), Positives = 98/259 (37%), Gaps = 53/259 (20%)
Query: 3 GWSCLVTGAGGFLGQ-------------RIIRLLVKEK-----ELKEIRVLDKAFGPELR 44
G S L+TGA GFLG+ ++I +LV+ K + + ++LD +++
Sbjct: 10 GKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLFEKVK 69
Query: 45 EEFSKLQNKTKLTVLEGDILDEPFLKRACQDV----SVIIHTACIIDVFGVTHRESIMNV 100
E + K + + + D K Q++ ++I H A + F T R ++ +
Sbjct: 70 EVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVR-FDDTLRHAV-QL 127
Query: 101 NVKGT-QLLLEACVQASVPVFIYTSS------------IEVAGPNSYKEIIQN------- 140
NV T QLLL A + FI+ S+ + P K+II +
Sbjct: 128 NVTATRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSLEWLDDA 187
Query: 141 --GHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTCALRPMYIYGEGSRFL 198
L WP Y ++K L E V + L +RP +
Sbjct: 188 IIDEITPKLIRDWPNIYTYTKALGEMVV-------QQESRNLNIAIIRPSIVGATWQEPF 240
Query: 199 SASINEALNNNGILSSVGK 217
++ NGI+ + GK
Sbjct: 241 PGWVDNINGPNGIIIATGK 259
>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
Length = 384
Score = 35.4 bits (80), Expect = 0.083
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 8/99 (8%)
Query: 67 PFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSSI 126
PF++ VSV TA D ++ + ++++ + L++ C++A+ FI+ S+
Sbjct: 117 PFIQLTSVGVSVFTLTALSAD----RYKAIVRPMDIQASHALMKICLKAA---FIWIISM 169
Query: 127 EVAGPNSYKEIIQNGHEEEPLENTWP-APYPHSKKLAEK 164
+A P + + HEE + APYPHS +L K
Sbjct: 170 LLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPK 208
>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
receptor [Homo sapiens]
Length = 368
Score = 35.4 bits (80), Expect = 0.083
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 8/99 (8%)
Query: 67 PFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSSI 126
PF++ VSV TA D ++ + ++++ + L++ C++A+ FI+ S+
Sbjct: 101 PFIQLTSVGVSVFTLTALSAD----RYKAIVRPMDIQASHALMKICLKAA---FIWIISM 153
Query: 127 EVAGPNSYKEIIQNGHEEEPLENTWP-APYPHSKKLAEK 164
+A P + + HEE + APYPHS +L K
Sbjct: 154 LLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPK 192
>gi|47419930 chondroitin sulfate proteoglycan 4 [Homo sapiens]
Length = 2322
Score = 30.4 bits (67), Expect = 2.7
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 6/62 (9%)
Query: 250 RGQFYYISDDTPHQSYDNL-NYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEIVSFLLRPI 308
+G+ Y+S D H +YD + N L + G + S SFP+++ ++L L P+
Sbjct: 738 QGRVRYLSTDPQHHAYDTVENLALEVQVGQEILSNLSFPVTIQRATVWMLR-----LEPL 792
Query: 309 YT 310
+T
Sbjct: 793 HT 794
>gi|24308324 fatty acyl CoA reductase 1 [Homo sapiens]
Length = 515
Score = 30.0 bits (66), Expect = 3.5
Identities = 37/145 (25%), Positives = 69/145 (47%), Gaps = 23/145 (15%)
Query: 3 GWSCLVTGAGGFLGQRIIRLLVKE-KELKEIRVLDKAFGPELREE----------FSKLQ 51
G + L+TGA GFLG+ ++ L++ ++ + VL + + +E F +L+
Sbjct: 10 GKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVLSGKLFDRLR 69
Query: 52 N-----KTKLTVLEGDILDEPFLKRACQDVSVIIHTACIIDVFGVTHR-----ESIMNVN 101
+ + K+ + + L +P L + +D VII + II T R + +N
Sbjct: 70 DENPDFREKIIAINSE-LTQPKLALSEEDKEVIIDSTNIIFHCAATVRFNENLRDAVQLN 128
Query: 102 VKGT-QLLLEACVQASVPVFIYTSS 125
V T QL+L A ++ VF++ S+
Sbjct: 129 VIATRQLILLAQQMKNLEVFMHVST 153
>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
Length = 980
Score = 28.9 bits (63), Expect = 7.8
Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
Query: 3 GWSCLVTGAGGFLGQRIIRLLVKEKELKEI---RVLDK------AFGPELREEFSKLQNK 53
GW+ L T G LG R+ LLV+ E + RVL+ GP R ++L+ +
Sbjct: 104 GWALLGTSLGPGLGPRVGPLLVRRGETLPVPGPRVLETRPALQGLLGPGTRLAVTELRGR 163
Query: 54 TKLTVLEGD 62
+L GD
Sbjct: 164 ARLCPESGD 172
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,192,717
Number of Sequences: 37866
Number of extensions: 622213
Number of successful extensions: 1409
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1371
Number of HSP's gapped (non-prelim): 22
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.