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Search of human proteins with 4504235
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504235 granzyme K precursor [Homo sapiens]
(264 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504235 granzyme K precursor [Homo sapiens] 546 e-156
gi|5453676 granzyme A precursor [Homo sapiens] 211 5e-55
gi|42544239 complement factor D preproprotein [Homo sapiens] 176 2e-44
gi|11496281 kallikrein 13 precursor [Homo sapiens] 160 8e-40
gi|4885369 granzyme M precursor [Homo sapiens] 156 2e-38
gi|15529990 granzyme H [Homo sapiens] 156 2e-38
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 154 1e-37
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 153 1e-37
gi|4506153 prostasin preproprotein [Homo sapiens] 152 3e-37
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 151 5e-37
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 151 5e-37
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 151 5e-37
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 148 5e-36
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 146 2e-35
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 146 2e-35
gi|4503149 cathepsin G preproprotein [Homo sapiens] 144 6e-35
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 144 8e-35
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 144 8e-35
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 143 1e-34
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 143 1e-34
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 143 1e-34
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 143 2e-34
gi|221625528 granzyme B precursor [Homo sapiens] 142 2e-34
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 142 2e-34
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 142 3e-34
gi|47551347 protease, serine-like 1 [Homo sapiens] 142 4e-34
gi|110815798 ovochymase 1 [Homo sapiens] 141 5e-34
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 140 1e-33
gi|4505881 plasminogen [Homo sapiens] 139 2e-33
gi|4504383 HGF activator preproprotein [Homo sapiens] 139 2e-33
>gi|4504235 granzyme K precursor [Homo sapiens]
Length = 264
Score = 546 bits (1408), Expect = e-156
Identities = 264/264 (100%), Positives = 264/264 (100%)
Query: 1 MTKFSSFSLFFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQ 60
MTKFSSFSLFFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQ
Sbjct: 1 MTKFSSFSLFFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQ 60
Query: 61 WVLTAAHCQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLV 120
WVLTAAHCQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLV
Sbjct: 61 WVLTAAHCQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLV 120
Query: 121 KLQTAAKLNKHVKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKL 180
KLQTAAKLNKHVKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKL
Sbjct: 121 KLQTAAKLNKHVKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKL 180
Query: 181 CNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKP 240
CNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKP
Sbjct: 181 CNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKP 240
Query: 241 GIYTLLTKKYQTWIKSNLVPPHTN 264
GIYTLLTKKYQTWIKSNLVPPHTN
Sbjct: 241 GIYTLLTKKYQTWIKSNLVPPHTN 264
>gi|5453676 granzyme A precursor [Homo sapiens]
Length = 262
Score = 211 bits (537), Expect = 5e-55
Identities = 104/232 (44%), Positives = 149/232 (64%), Gaps = 8/232 (3%)
Query: 26 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 85
+IIGG EV+PHSRP+M + +C G LI WVLTAAHC + V+LGAH
Sbjct: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLN----KRSQVILGAH 83
Query: 86 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSK-TSLR 144
S+++ E +KQ + +KK P+ + D+ L++L AK+NK+V +LH+ K ++
Sbjct: 84 SITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVK 143
Query: 145 SGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAK 204
GT C+V GWG T +S SDTLREV +T++ RK+CN +++YN +P I +MVCAG +
Sbjct: 144 PGTMCQVAGWGRTH-NSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202
Query: 205 GQKDSCKGDSGGPLICKGVFHAIVSGG--HECGVATKPGIYTLLTKKYQTWI 254
G +DSC GDSG PL+C+GVF + S G ++CG PG+Y LL+KK+ WI
Sbjct: 203 GGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254
>gi|42544239 complement factor D preproprotein [Homo sapiens]
Length = 253
Score = 176 bits (445), Expect = 2e-44
Identities = 100/234 (42%), Positives = 140/234 (59%), Gaps = 9/234 (3%)
Query: 27 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 86
I+GG+E H+RP+MAS+Q G H+CGGVL+ QWVL+AAHC G+ V+LGAHS
Sbjct: 26 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGK-VQVLLGAHS 84
Query: 87 LSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKML-HIRSKTSLRS 145
LS+ E SK+ ++ + +P D +D++L++L A L V+ L R +
Sbjct: 85 LSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAP 144
Query: 146 GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKG 205
GT C V GWG + RP D+L+ V + VL R CN +++++G IT+ ++CA
Sbjct: 145 GTLCDVAGWGIVNHAGRRP-DSLQHVLLPVLDRATCNRRTHHDG--AITERLMCA--ESN 199
Query: 206 QKDSCKGDSGGPLICKGVFHAIV-SGGHECGVATKPGIYTLLTKKYQTWIKSNL 258
++DSCKGDSGGPL+C GV +V SG CG KPGIYT + Y WI S L
Sbjct: 200 RRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVA-SYAAWIDSVL 252
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 160 bits (406), Expect = 8e-40
Identities = 90/235 (38%), Positives = 131/235 (55%), Gaps = 15/235 (6%)
Query: 29 GGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHSLS 88
GG PHS+P+ A++ G +CGGVL+ P+WVLTAAHC K V LG H+L
Sbjct: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLK-----VYLGKHALG 92
Query: 89 KNEASKQTLEIKKFIPFSRVTSDP----QSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLR 144
+ EA +Q E+ IP P +DIML++LQ+ +L +++ L + L
Sbjct: 93 RVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLT 152
Query: 145 SGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAK 204
GT C+V+GWG T + TL+ + + S + C + Y G IT +M+CAG +
Sbjct: 153 PGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEEC--RQVYPGK--ITDNMLCAGTKE 208
Query: 205 GQKDSCKGDSGGPLICKGVFHAIVS-GGHECGVATKPGIYTLLTKKYQTWIKSNL 258
G KDSC+GDSGGPL+C + IVS G CG +PG+YT ++ +Y WI+ +
Sbjct: 209 GGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVS-RYVLWIRETI 262
>gi|4885369 granzyme M precursor [Homo sapiens]
Length = 257
Score = 156 bits (395), Expect = 2e-38
Identities = 102/254 (40%), Positives = 145/254 (57%), Gaps = 16/254 (6%)
Query: 8 SLFFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAH 67
SL L +GA F +IIGG+EV PHSRP+MAS+Q G H+CGGVL+ P+WVLTAAH
Sbjct: 7 SLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAH 66
Query: 68 CQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQ-SNDIMLVKLQTAA 126
C + + +VLG H+L ++ T IK I R P ND+ L++L
Sbjct: 67 CLAQ--RMAQLRLVLGLHTL---DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKV 121
Query: 127 KLNKHVKMLHIRSKTS-LRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQS 185
K ++ ++ L + SK + +GT+C + GWG T R S LRE+ + VL ++CN+
Sbjct: 122 KPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGG-RLSRVLRELDLQVLDTRMCNNSR 180
Query: 186 YYNGDPFITKDMVC-AGDAKGQKDSCKGDSGGPLIC-KG-VFHAIVS-GGHECGVATKPG 241
++NG ++ MVC A D+K Q CKGDSGGPL+C KG V ++S C KP
Sbjct: 181 FWNGS--LSPSMVCLAADSKDQA-PCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPP 237
Query: 242 IYTLLTKKYQTWIK 255
+ T + Y +WI+
Sbjct: 238 VATAVA-PYVSWIR 250
>gi|15529990 granzyme H [Homo sapiens]
Length = 246
Score = 156 bits (395), Expect = 2e-38
Identities = 96/253 (37%), Positives = 140/253 (55%), Gaps = 17/253 (6%)
Query: 10 FFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQY---GGHHVCGGVLIDPQWVLTAA 66
F L++ +T EIIGG E PHSRP+MA +Q+ CGG+L+ +VLTAA
Sbjct: 4 FLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAA 63
Query: 67 HCQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAA 126
HCQ G S V LGAH++ + E ++Q + +K+ IP SNDIML++L+ A
Sbjct: 64 HCQ-----GSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKA 118
Query: 127 KLNKHVKMLHI-RSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQS 185
K V+ L + SK ++ G C V GWG +L + TL+EV +TV +K C +
Sbjct: 119 KWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTL--ATTLQEVLLTV--QKDCQCER 174
Query: 186 YYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTL 245
++G+ + +C GD K + KGDSGGPL+CK V I+S G++ G T PG+Y +
Sbjct: 175 LFHGN-YSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKG--TPPGVY-I 230
Query: 246 LTKKYQTWIKSNL 258
+ WIK +
Sbjct: 231 KVSHFLPWIKRTM 243
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 154 bits (388), Expect = 1e-37
Identities = 94/255 (36%), Positives = 138/255 (54%), Gaps = 17/255 (6%)
Query: 6 SFSLFFLIVGAYMTHVCFNME-IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLT 64
++ L+ GA+ H + ++GG E PHS+P+ A++ G +CGGVL+ WVLT
Sbjct: 11 TWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLT 70
Query: 65 AAHCQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIP---FSRVTSDPQSNDIMLVK 121
AAHC K TV LG HSL + +Q + + + IP ++ + ++D+ML++
Sbjct: 71 AAHC-----KKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQ 125
Query: 122 LQTAAKLNKHVKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLC 181
L+ A L VK + + + + G KC V+GWG DTL V + +K C
Sbjct: 126 LRDQASLGSKVKPISLADHCT-QPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKC 184
Query: 182 NSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHE-CGVATKP 240
+ Y G IT MVCAG +KG D+C+GDSGGPL+C G I S G + CG + KP
Sbjct: 185 --EDAYPGQ--ITDGMVCAGSSKG-ADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKP 239
Query: 241 GIYTLLTKKYQTWIK 255
G+YT + +Y WIK
Sbjct: 240 GVYTNIC-RYLDWIK 253
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 153 bits (387), Expect = 1e-37
Identities = 90/234 (38%), Positives = 130/234 (55%), Gaps = 16/234 (6%)
Query: 26 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 85
+++GG E PHS+P+ A++ G +CGGVL+ WVLTAAHC K TV LG H
Sbjct: 77 KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC-----KKPKYTVRLGDH 131
Query: 86 SLSKNEASKQTLEIKKFIP---FSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTS 142
SL + +Q + + + IP ++ + ++D+ML++L+ A L VK + + +
Sbjct: 132 SLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCT 191
Query: 143 LRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGD 202
+ G KC V+GWG DTL V + +K C + Y G IT MVCAG
Sbjct: 192 -QPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKC--EDAYPGQ--ITDGMVCAGS 246
Query: 203 AKGQKDSCKGDSGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTWIK 255
+KG D+C+GDSGGPL+C G I S G + CG + KPG+YT + +Y WIK
Sbjct: 247 SKG-ADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNIC-RYLDWIK 298
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 152 bits (384), Expect = 3e-37
Identities = 88/242 (36%), Positives = 128/242 (52%), Gaps = 11/242 (4%)
Query: 27 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 86
I GG P+ SI Y G HVCGG L+ QWVL+AAHC ++ V LGAH
Sbjct: 45 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 104
Query: 87 LSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSKTSLRS 145
L + +K IP + DI L++L +++++ + + + S +
Sbjct: 105 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPN 164
Query: 146 GTKCKVTGWGATDPD-SLRPSDTLREVTVTVLSRKLCNSQSYYNGDP----FITKDMVCA 200
G C VTGWG P SL L+++ V ++SR+ CN + P F+ +DMVCA
Sbjct: 165 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCA 224
Query: 201 GDAKGQKDSCKGDSGGPLIC--KGVFH--AIVSGGHECGVATKPGIYTLLTKKYQTWIKS 256
G +G KD+C+GDSGGPL C +G+++ IVS G CG +PG+YT L Y +WI+S
Sbjct: 225 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYT-LASSYASWIQS 283
Query: 257 NL 258
+
Sbjct: 284 KV 285
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 151 bits (382), Expect = 5e-37
Identities = 90/238 (37%), Positives = 133/238 (55%), Gaps = 18/238 (7%)
Query: 27 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHC-QYRFTKGQSPTVVLGAH 85
II G E PHS+P+ A++ +CG LI P+W+LTAAHC + R+ V LG H
Sbjct: 22 IIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYI------VHLGQH 75
Query: 86 SLSKNEASKQTLEIKKFIPF----SRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKT 141
+L K E +QT + P + + + NDIMLVK+ + + V+ L + S+
Sbjct: 76 NLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRC 135
Query: 142 SLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAG 201
+ +GT C ++GWG+T LR TLR +T++ + C ++ Y G+ IT MVCA
Sbjct: 136 -VTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC--ENAYPGN--ITDTMVCAS 190
Query: 202 DAKGQKDSCKGDSGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTWIKSNL 258
+G KDSC+GDSGGPL+C I+S G + C + KPG+YT + KY WI+ +
Sbjct: 191 VQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVC-KYVDWIQETM 247
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 151 bits (382), Expect = 5e-37
Identities = 90/238 (37%), Positives = 133/238 (55%), Gaps = 18/238 (7%)
Query: 27 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHC-QYRFTKGQSPTVVLGAH 85
II G E PHS+P+ A++ +CG LI P+W+LTAAHC + R+ V LG H
Sbjct: 54 IIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYI------VHLGQH 107
Query: 86 SLSKNEASKQTLEIKKFIPF----SRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKT 141
+L K E +QT + P + + + NDIMLVK+ + + V+ L + S+
Sbjct: 108 NLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRC 167
Query: 142 SLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAG 201
+ +GT C ++GWG+T LR TLR +T++ + C ++ Y G+ IT MVCA
Sbjct: 168 -VTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC--ENAYPGN--ITDTMVCAS 222
Query: 202 DAKGQKDSCKGDSGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTWIKSNL 258
+G KDSC+GDSGGPL+C I+S G + C + KPG+YT + KY WI+ +
Sbjct: 223 VQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVC-KYVDWIQETM 279
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 151 bits (382), Expect = 5e-37
Identities = 90/238 (37%), Positives = 133/238 (55%), Gaps = 18/238 (7%)
Query: 27 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHC-QYRFTKGQSPTVVLGAH 85
II G E PHS+P+ A++ +CG LI P+W+LTAAHC + R+ V LG H
Sbjct: 22 IIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYI------VHLGQH 75
Query: 86 SLSKNEASKQTLEIKKFIPF----SRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKT 141
+L K E +QT + P + + + NDIMLVK+ + + V+ L + S+
Sbjct: 76 NLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRC 135
Query: 142 SLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAG 201
+ +GT C ++GWG+T LR TLR +T++ + C ++ Y G+ IT MVCA
Sbjct: 136 -VTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC--ENAYPGN--ITDTMVCAS 190
Query: 202 DAKGQKDSCKGDSGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTWIKSNL 258
+G KDSC+GDSGGPL+C I+S G + C + KPG+YT + KY WI+ +
Sbjct: 191 VQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVC-KYVDWIQETM 247
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 148 bits (373), Expect = 5e-36
Identities = 86/236 (36%), Positives = 133/236 (56%), Gaps = 14/236 (5%)
Query: 26 EIIGGKEVSPHSRPFMASIQYGGHH--VCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLG 83
+IIGG + S+P+ A++ G +CGG L+ QWV+TAAHC + V LG
Sbjct: 40 KIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQ-----VALG 94
Query: 84 AHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSL 143
H+L + EA++Q L + + + S ND+ML++LQ A++ + V+ + + ++
Sbjct: 95 KHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEV-TQACA 153
Query: 144 RSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDA 203
GT C+V+GWG R +L+ V + + ++C Q Y IT MVCAG
Sbjct: 154 SPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVC--QKAYPRT--ITPGMVCAGVP 209
Query: 204 KGQKDSCKGDSGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTWIKSNL 258
+G KDSC+GDSGGPL+C+G +VS G E C + PG+YT L KY++WI+ +
Sbjct: 210 QGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLC-KYRSWIEETM 264
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 146 bits (369), Expect = 2e-35
Identities = 89/246 (36%), Positives = 129/246 (52%), Gaps = 25/246 (10%)
Query: 27 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 86
I+GG E HS+P+ + G VCGGVL+ PQWVLTAAHC + +S ++LG HS
Sbjct: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHC----IRNKS-VILLGRHS 79
Query: 87 LSKNEASKQTLEIKKFIP------------FSRVTSDPQSNDIMLVKLQTAAKLNKHVKM 134
L E + Q ++ P F R D S+D+ML++L A+L VK+
Sbjct: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLR-PGDDSSHDLMLLRLSEPAELTDAVKV 138
Query: 135 LHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFIT 194
+ + ++ GT C +GWG+ +P+ L+ V + V+S +C +T
Sbjct: 139 MDLPTQEP-ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK----VT 193
Query: 195 KDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTW 253
K M+CAG G K +C GDSGGPL+C GV I S G E C + +P +YT + Y+ W
Sbjct: 194 KFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVV-HYRKW 252
Query: 254 IKSNLV 259
IK +V
Sbjct: 253 IKDTIV 258
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 146 bits (368), Expect = 2e-35
Identities = 84/233 (36%), Positives = 124/233 (53%), Gaps = 12/233 (5%)
Query: 26 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 85
+I+GG +S P+ S+ G+H CGG LI+ QWV++A HC + V LG H
Sbjct: 23 KIVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYKSRIQ-----VRLGEH 76
Query: 86 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRS 145
++ E ++Q + K I + +NDIML+KL + A +N V + + + +
Sbjct: 77 NIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPA-T 135
Query: 146 GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKG 205
GTKC ++GWG T D L+ + VLS+ C + Y G IT +M C G +G
Sbjct: 136 GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEAS--YPGK--ITSNMFCVGFLEG 191
Query: 206 QKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 258
KDSC+GDSGGP++C G +VS G C KPG+YT + Y WIK+ +
Sbjct: 192 GKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKV-YNYVKWIKNTI 243
>gi|4503149 cathepsin G preproprotein [Homo sapiens]
Length = 255
Score = 144 bits (364), Expect = 6e-35
Identities = 89/237 (37%), Positives = 133/237 (56%), Gaps = 18/237 (7%)
Query: 26 EIIGGKEVSPHSRPFMASIQY---GGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVL 82
EIIGG+E PHSRP+MA +Q G CGG L+ +VLTAAHC G + V L
Sbjct: 20 EIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCW-----GSNINVTL 74
Query: 83 GAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSKT 141
GAH++ + E ++Q + ++ I + NDIML++L + N++V + + R++
Sbjct: 75 GAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQE 134
Query: 142 SLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAG 201
LR GT C V GWG R +DTLREV + V + C + + + DP + +C G
Sbjct: 135 GLRPGTLCTVAGWGRVS--MRRGTDTLREVQLRVQRDRQC-LRIFGSYDP---RRQICVG 188
Query: 202 DAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 258
D + +K + KGDSGGPL+C V H IVS G GV P ++T ++ + WI++ +
Sbjct: 189 DRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGV--PPEVFTRVS-SFLPWIRTTM 242
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 144 bits (363), Expect = 8e-35
Identities = 85/234 (36%), Positives = 130/234 (55%), Gaps = 14/234 (5%)
Query: 26 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 85
+++ G S P+ A++ GH +CGGVLI P WVLTAAHC K + V LG H
Sbjct: 21 KLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC-----KKPNLQVFLGKH 75
Query: 86 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRS 145
+L + E+S++ + + + + DIML++L AKL++ ++ L + S +
Sbjct: 76 NLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANT 135
Query: 146 GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKG 205
T C + GWG T DT++ + ++SR+ C + Y G IT++M+CAGD K
Sbjct: 136 -TSCHILGWGKTADGDF--PDTIQCAYIHLVSREEC--EHAYPGQ--ITQNMLCAGDEKY 188
Query: 206 QKDSCKGDSGGPLICKGVFHAIVSGGH-ECGVATKPGIYTLLTKKYQTWIKSNL 258
KDSC+GDSGGPL+C +VS G+ CG KPG+YT + +Y WI+ +
Sbjct: 189 GKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVC-RYTNWIQKTI 241
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 144 bits (363), Expect = 8e-35
Identities = 85/234 (36%), Positives = 130/234 (55%), Gaps = 14/234 (5%)
Query: 26 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 85
+++ G S P+ A++ GH +CGGVLI P WVLTAAHC K + V LG H
Sbjct: 21 KLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC-----KKPNLQVFLGKH 75
Query: 86 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRS 145
+L + E+S++ + + + + DIML++L AKL++ ++ L + S +
Sbjct: 76 NLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANT 135
Query: 146 GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKG 205
T C + GWG T DT++ + ++SR+ C + Y G IT++M+CAGD K
Sbjct: 136 -TSCHILGWGKTADGDF--PDTIQCAYIHLVSREEC--EHAYPGQ--ITQNMLCAGDEKY 188
Query: 206 QKDSCKGDSGGPLICKGVFHAIVSGGH-ECGVATKPGIYTLLTKKYQTWIKSNL 258
KDSC+GDSGGPL+C +VS G+ CG KPG+YT + +Y WI+ +
Sbjct: 189 GKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVC-RYTNWIQKTI 241
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 143 bits (361), Expect = 1e-34
Identities = 87/244 (35%), Positives = 133/244 (54%), Gaps = 23/244 (9%)
Query: 27 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 86
I+GG E HS+P+ ++ G CGGVL+ PQWVLTAAHC + + V LG H+
Sbjct: 25 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK-----NSQVWLGRHN 79
Query: 87 LSKNEASKQTLEIKKFIPF-----------SRVTSDPQSNDIMLVKLQTAAKLNKHVKML 135
L + E + Q + + P S + S+D+ML++L AK+ VK+L
Sbjct: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139
Query: 136 HIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITK 195
+ ++ GT C +GWG+ +P+ +L+ V++ +LS +C +++Y +T+
Sbjct: 140 GLPTQEP-ALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC-ARAY---SEKVTE 194
Query: 196 DMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTWI 254
M+CAG G KD+C GDSGGPL+C GV I S G E C + KP +YT + Y+ WI
Sbjct: 195 FMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVV-HYRKWI 253
Query: 255 KSNL 258
K +
Sbjct: 254 KDTI 257
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 143 bits (361), Expect = 1e-34
Identities = 86/233 (36%), Positives = 125/233 (53%), Gaps = 12/233 (5%)
Query: 26 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 85
+I+GG +S P+ S+ G H CGG LI QWV++AAHC Y+ T+ Q V LG H
Sbjct: 80 KIVGGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHC-YK-TRIQ---VRLGEH 133
Query: 86 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRS 145
++ E ++Q + K I + D NDIML+KL + A +N V + + + +
Sbjct: 134 NIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPA-A 192
Query: 146 GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKG 205
GT+C ++GWG T D L+ + VL++ C + Y G IT M C G +G
Sbjct: 193 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKAS--YPGK--ITNSMFCVGFLEG 248
Query: 206 QKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 258
KDSC+ DSGGP++C G +VS GH C +PG+YT + Y WIK +
Sbjct: 249 GKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKV-YNYVDWIKDTI 300
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 143 bits (361), Expect = 1e-34
Identities = 86/233 (36%), Positives = 125/233 (53%), Gaps = 12/233 (5%)
Query: 26 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 85
+I+GG +S P+ S+ G H CGG LI QWV++AAHC Y+ T+ Q V LG H
Sbjct: 23 KIVGGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHC-YK-TRIQ---VRLGEH 76
Query: 86 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRS 145
++ E ++Q + K I + D NDIML+KL + A +N V + + + +
Sbjct: 77 NIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPA-A 135
Query: 146 GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKG 205
GT+C ++GWG T D L+ + VL++ C + Y G IT M C G +G
Sbjct: 136 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKAS--YPGK--ITNSMFCVGFLEG 191
Query: 206 QKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 258
KDSC+ DSGGP++C G +VS GH C +PG+YT + Y WIK +
Sbjct: 192 GKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKV-YNYVDWIKDTI 243
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 143 bits (360), Expect = 2e-34
Identities = 89/244 (36%), Positives = 127/244 (52%), Gaps = 22/244 (9%)
Query: 26 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 85
+++ G E +PHS+P+ ++ G CG LI P WVL+AAHCQ RF + V LG H
Sbjct: 21 KLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMR-----VRLGEH 75
Query: 86 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRS 145
+L K + +Q + IP R + NDIML++L A+LN V+ + ++
Sbjct: 76 NLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCP-HP 134
Query: 146 GTKCKVTGWG---------ATDPDS-LRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITK 195
G C V+GWG A P S + DTL ++++S C+ Y G +T
Sbjct: 135 GEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKS--YPGR--LTN 190
Query: 196 DMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGH-ECGVATKPGIYTLLTKKYQTWI 254
MVCAG +SC+GDSGGPL+C G+ IVS G C TKPG+YT + Y WI
Sbjct: 191 TMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVC-HYLEWI 249
Query: 255 KSNL 258
+ +
Sbjct: 250 RETM 253
>gi|221625528 granzyme B precursor [Homo sapiens]
Length = 247
Score = 142 bits (359), Expect = 2e-34
Identities = 93/237 (39%), Positives = 124/237 (52%), Gaps = 16/237 (6%)
Query: 26 EIIGGKEVSPHSRPFMASIQYGGHHV---CGGVLIDPQWVLTAAHCQYRFTKGQSPTVVL 82
EIIGG E PHSRP+MA + CGG LI +VLTAAHC G S V L
Sbjct: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW-----GSSINVTL 74
Query: 83 GAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRS-KT 141
GAH++ + E ++Q + +K+ IP SNDIML++L+ AK + V+ L + S K
Sbjct: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134
Query: 142 SLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAG 201
++ G C V GWG T P + S TL+EV +TV + C S + D I +C G
Sbjct: 135 QVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE---LCVG 190
Query: 202 DAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 258
D + +K S KGDSGGPL+C V IVS G G+ P + WIK +
Sbjct: 191 DPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGM---PPRACTKVSSFVHWIKKTM 244
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 142 bits (359), Expect = 2e-34
Identities = 91/248 (36%), Positives = 131/248 (52%), Gaps = 17/248 (6%)
Query: 13 IVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRF 72
+ G+ ++ C +II G++ SPHS+P+ A++ C GVL+ PQWVL+AAHC
Sbjct: 19 VAGSLVSGSC--SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ-- 74
Query: 73 TKGQSPTVVLGAHSL-SKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKH 131
S T+ LG HSL + E Q +E + +ND+ML+KL + +
Sbjct: 75 ---NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDT 131
Query: 132 VKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDP 191
++ + I S+ +G C V+GWG + R L+ V V+V+S ++C S+ Y DP
Sbjct: 132 IRSISIASQCP-TAGNSCLVSGWGLL--ANGRMPTVLQCVNVSVVSEEVC-SKLY---DP 184
Query: 192 FITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVS-GGHECGVATKPGIYTLLTKKY 250
M CAG QKDSC GDSGGPLIC G +VS G CG PG+YT L K+
Sbjct: 185 LYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLC-KF 243
Query: 251 QTWIKSNL 258
WI+ +
Sbjct: 244 TEWIEKTV 251
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 142 bits (358), Expect = 3e-34
Identities = 83/241 (34%), Positives = 124/241 (51%), Gaps = 10/241 (4%)
Query: 23 FNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVL 82
++ I+GG P+ AS+Q+ G+H+CGG +I P W++TAAHC Y +S T+ +
Sbjct: 213 YSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQV 272
Query: 83 GAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSKT 141
G SL N A +E K + S+ NDI L+KL N+ ++ + + S+
Sbjct: 273 GLVSLLDNPAPSHLVE--KIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEE 330
Query: 142 SLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAG 201
+ G C +GWGAT+ + S L V ++S K+CN + Y G I+ M+CAG
Sbjct: 331 NFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGG--IISPSMLCAG 388
Query: 202 DAKGQKDSCKGDSGGPLICK----GVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSN 257
G DSC+GDSGGPL+C+ S G C KPG+YT +T + WI
Sbjct: 389 YLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVT-SFLDWIHEQ 447
Query: 258 L 258
+
Sbjct: 448 M 448
>gi|47551347 protease, serine-like 1 [Homo sapiens]
Length = 283
Score = 142 bits (357), Expect = 4e-34
Identities = 89/233 (38%), Positives = 129/233 (55%), Gaps = 11/233 (4%)
Query: 26 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 85
+IIGG EV+PHSRP+MAS+++GG H CGG L+ +WV++AAHC + ++ VVLGAH
Sbjct: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHC-FSHRDLRTGLVVLGAH 91
Query: 86 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI--RSKTSL 143
LS E ++Q I +NDI L++L +A L V +L + R
Sbjct: 92 VLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPP 151
Query: 144 RSGTKCKVTGWG-ATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGD 202
+GT+C+V GWG +D + L P L E V VL +CNS + G +T +GD
Sbjct: 152 TAGTRCRVAGWGFVSDFEELPPG--LMEAKVRVLDPDVCNSS--WKGHLTLTMLCTRSGD 207
Query: 203 AKGQKDSCKGDSGGPLICKGVFHAIVS-GGHECGVATKPGIYTLLTKKYQTWI 254
+ ++ C DSGGPL+C+ H +VS G CG P +YT ++ + WI
Sbjct: 208 SH-RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVS-AFVAWI 258
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 141 bits (356), Expect = 5e-34
Identities = 86/243 (35%), Positives = 131/243 (53%), Gaps = 11/243 (4%)
Query: 27 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 86
I GG+E PH P+ +++ G + CGG +I+P W+LTAAHC S T++ G H
Sbjct: 575 IAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHD 634
Query: 87 LSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSKTSLRS 145
+ E+++Q K I + +DI L++L + + N V+ + + S L S
Sbjct: 635 RNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFS 694
Query: 146 GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDP-FITKDMVCAG-DA 203
C VTGWG+ D S L+++ V VL R++C +YY+ P IT+ M+CAG A
Sbjct: 695 SEICAVTGWGSISADGGLAS-RLQQIQVHVLEREVC-EHTYYSAHPGGITEKMICAGFAA 752
Query: 204 KGQKDSCKGDSGGPLICKG-----VFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 258
G+KD C+GDSGGPL+C+ V + IVS G C KPG++ + + WI+S +
Sbjct: 753 SGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARV-MIFLDWIQSKI 811
Query: 259 VPP 261
P
Sbjct: 812 NGP 814
Score = 94.4 bits (233), Expect = 9e-20
Identities = 59/187 (31%), Positives = 95/187 (50%), Gaps = 5/187 (2%)
Query: 39 PFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQ--SPTVVLGAHSLSKNEASKQT 96
P+ S++ HH CGG LI V+TAAHC ++ Q + TV G +SL + + +Q
Sbjct: 59 PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQN 118
Query: 97 LEIKKFIPFSRVTS-DPQSNDIMLVKLQTAAKLNKHVKMLHIR-SKTSLRSGTKCKVTGW 154
+ + K I S + S DI L+ L+ K V+ + + S + G C +GW
Sbjct: 119 IPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGW 178
Query: 155 GATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDS 214
G S S+ L+E+ + ++ + CN+ P + + M+CAG D+C+GDS
Sbjct: 179 GKISKTS-EYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDS 237
Query: 215 GGPLICK 221
GGPL+C+
Sbjct: 238 GGPLVCR 244
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 140 bits (353), Expect = 1e-33
Identities = 79/234 (33%), Positives = 125/234 (53%), Gaps = 9/234 (3%)
Query: 27 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 86
I+GG+ V+P P+ AS+ G H CGG ++ P+WV+TAAHC + F + + + A
Sbjct: 218 IVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGL 277
Query: 87 LSKNEA-SKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTS-LR 144
+S + Q +++ IP ++ D+ L++LQTA + V + + +K
Sbjct: 278 VSHSAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFP 337
Query: 145 SGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAK 204
G++C V+GWG T P SD L++ V + S +LCNS Y+G +T M+CAG
Sbjct: 338 KGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSG--ALTPRMLCAGYLD 395
Query: 205 GQKDSCKGDSGGPLICKG----VFHAIVSGGHECGVATKPGIYTLLTKKYQTWI 254
G+ D+C+GDSGGPL+C +VS G C PG+Y + ++ WI
Sbjct: 396 GRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVYAKVA-EFLDWI 448
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 139 bits (351), Expect = 2e-33
Identities = 84/235 (35%), Positives = 122/235 (51%), Gaps = 17/235 (7%)
Query: 27 IIGGKEVSPHSRPFMASIQYG-GHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 85
++GG PHS P+ S++ G H CGG LI P+WVLTAAHC + + S V+LGAH
Sbjct: 581 VVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAH 640
Query: 86 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKT-SLR 144
E Q +E+ SR+ +P DI L+KL + A + V + S +
Sbjct: 641 QEVNLEPHVQEIEV------SRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVA 694
Query: 145 SGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAK 204
T+C +TGWG T + L+E + V+ K+CN + NG + +CAG
Sbjct: 695 DRTECFITGWGET--QGTFGAGLLKEAQLPVIENKVCNRYEFLNGR--VQSTELCAGHLA 750
Query: 205 GQKDSCKGDSGGPLIC----KGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIK 255
G DSC+GDSGGPL+C K + + S G C KPG+Y ++ ++ TWI+
Sbjct: 751 GGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVS-RFVTWIE 804
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 139 bits (351), Expect = 2e-33
Identities = 84/245 (34%), Positives = 133/245 (54%), Gaps = 14/245 (5%)
Query: 27 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 86
IIGG P S P++A+I Y G C G L+ WV++AAHC S +VVLG H
Sbjct: 408 IIGGSSSLPGSHPWLAAI-YIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 466
Query: 87 LSKNEASKQTLEIKKFIPFSRVT-SDPQSNDIMLVKLQ----TAAKLNKHVKMLHI-RSK 140
++ QT I+K+IP++ + +P +D++L++L+ A ++ V+ + +
Sbjct: 467 FNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPG 526
Query: 141 TSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCA 200
++ +G KC++ GWG D + S +LRE V +++ C+S Y D I+ +M+CA
Sbjct: 527 STFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGAD--ISPNMLCA 584
Query: 201 GDAKGQKDSCKGDSGGPLICK----GVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKS 256
G + D+C+GDSGGPL C+ + I+S G CG KPG+YT + Y WI
Sbjct: 585 GYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVA-NYVDWIND 643
Query: 257 NLVPP 261
+ PP
Sbjct: 644 RIRPP 648
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,345,009
Number of Sequences: 37866
Number of extensions: 432933
Number of successful extensions: 1373
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 735
Number of HSP's gapped (non-prelim): 185
length of query: 264
length of database: 18,247,518
effective HSP length: 100
effective length of query: 164
effective length of database: 14,460,918
effective search space: 2371590552
effective search space used: 2371590552
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.