Guide to the Human Genome
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Search of human proteins with 4504165

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504165 gelsolin isoform a precursor [Homo sapiens]
         (782 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504165 gelsolin isoform a precursor [Homo sapiens]               1584   0.0  
gi|189083782 gelsolin isoform c [Homo sapiens]                       1491   0.0  
gi|189083780 gelsolin isoform c [Homo sapiens]                       1491   0.0  
gi|38044288 gelsolin isoform b [Homo sapiens]                        1485   0.0  
gi|189083778 gelsolin isoform b [Homo sapiens]                       1485   0.0  
gi|189083776 gelsolin isoform b [Homo sapiens]                       1485   0.0  
gi|189083774 gelsolin isoform b [Homo sapiens]                       1485   0.0  
gi|189083772 gelsolin isoform b [Homo sapiens]                       1485   0.0  
gi|162951877 scinderin isoform 1 [Homo sapiens]                       915   0.0  
gi|194394237 villin 1 [Homo sapiens]                                  684   0.0  
gi|17572824 advillin [Homo sapiens]                                   642   0.0  
gi|14916473 scinderin isoform 2 [Homo sapiens]                        601   e-172
gi|94721268 villin-like protein [Homo sapiens]                        503   e-142
gi|63252913 gelsolin-like capping protein [Homo sapiens]              342   6e-94
gi|4503743 flightless I homolog [Homo sapiens]                        259   9e-69
gi|150417973 supervillin isoform 2 [Homo sapiens]                     139   1e-32
gi|150417971 supervillin isoform 1 [Homo sapiens]                     139   1e-32
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]          32   3.0  
gi|139394599 hypermethylated in cancer 2 [Homo sapiens]                31   3.9  
gi|109637761 calpastatin isoform g [Homo sapiens]                      31   5.1  
gi|239754618 PREDICTED: hypothetical protein isoform 1 [Homo sap...    30   6.6  
gi|239754616 PREDICTED: hypothetical protein isoform 2 [Homo sap...    30   6.6  
gi|239749171 PREDICTED: hypothetical protein isoform 1 [Homo sap...    30   6.6  
gi|239749169 PREDICTED: hypothetical protein isoform 2 [Homo sap...    30   6.6  
gi|239743240 PREDICTED: hypothetical protein isoform 1 [Homo sap...    30   6.6  
gi|239743238 PREDICTED: hypothetical protein isoform 2 [Homo sap...    30   6.6  
gi|239508915 PREDICTED: hypothetical protein isoform 1 [Homo sap...    30   6.6  
gi|239508913 PREDICTED: hypothetical protein isoform 2 [Homo sap...    30   6.6  
gi|38569394 inhibitor of kappa light polypeptide gene enhancer i...    30   6.6  
gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]         30   6.6  

>gi|4504165 gelsolin isoform a precursor [Homo sapiens]
          Length = 782

 Score = 1584 bits (4101), Expect = 0.0
 Identities = 782/782 (100%), Positives = 782/782 (100%)

Query: 1   MAPHRPAPALLCALSLALCALSLPVRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFL 60
           MAPHRPAPALLCALSLALCALSLPVRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFL
Sbjct: 1   MAPHRPAPALLCALSLALCALSLPVRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFL 60

Query: 61  KAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNEC 120
           KAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNEC
Sbjct: 61  KAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNEC 120

Query: 121 SQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVV 180
           SQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVV
Sbjct: 121 SQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVV 180

Query: 181 PNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA 240
           PNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA
Sbjct: 181 PNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA 240

Query: 241 TQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKL 300
           TQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKL
Sbjct: 241 TQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKL 300

Query: 301 YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 360
           YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK
Sbjct: 301 YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 360

Query: 361 TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVERV 420
           TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVERV
Sbjct: 361 TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVERV 420

Query: 421 PFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNY 480
           PFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNY
Sbjct: 421 PFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNY 480

Query: 481 RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFG 540
           RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFG
Sbjct: 481 RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFG 540

Query: 541 GKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPS 600
           GKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPS
Sbjct: 541 GKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPS 600

Query: 601 AAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDK 660
           AAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDK
Sbjct: 601 AAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDK 660

Query: 661 KMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEK 720
           KMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEK
Sbjct: 661 KMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEK 720

Query: 721 TEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVDPLDRAMAEL 780
           TEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVDPLDRAMAEL
Sbjct: 721 TEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVDPLDRAMAEL 780

Query: 781 AA 782
           AA
Sbjct: 781 AA 782


>gi|189083782 gelsolin isoform c [Homo sapiens]
          Length = 742

 Score = 1491 bits (3861), Expect = 0.0
 Identities = 734/734 (100%), Positives = 734/734 (100%)

Query: 49  PNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNL 108
           PNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNL
Sbjct: 9   PNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNL 68

Query: 109 QYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYK 168
           QYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYK
Sbjct: 69  QYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYK 128

Query: 169 KGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWC 228
           KGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWC
Sbjct: 129 KGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWC 188

Query: 229 GSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTA 288
           GSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTA
Sbjct: 189 GSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTA 248

Query: 289 KEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGK 348
           KEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGK
Sbjct: 249 KEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGK 308

Query: 349 QANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLS 408
           QANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLS
Sbjct: 309 QANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLS 368

Query: 409 YLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQF 468
           YLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQF
Sbjct: 369 YLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQF 428

Query: 469 YGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQ 528
           YGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQ
Sbjct: 429 YGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQ 488

Query: 529 GKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGAL 588
           GKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGAL
Sbjct: 489 GKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGAL 548

Query: 589 NSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGK 648
           NSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGK
Sbjct: 549 NSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGK 608

Query: 649 AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF 708
           AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF
Sbjct: 609 AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF 668

Query: 709 VWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 768
           VWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW
Sbjct: 669 VWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 728

Query: 769 SVDPLDRAMAELAA 782
           SVDPLDRAMAELAA
Sbjct: 729 SVDPLDRAMAELAA 742


>gi|189083780 gelsolin isoform c [Homo sapiens]
          Length = 742

 Score = 1491 bits (3861), Expect = 0.0
 Identities = 734/734 (100%), Positives = 734/734 (100%)

Query: 49  PNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNL 108
           PNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNL
Sbjct: 9   PNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNL 68

Query: 109 QYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYK 168
           QYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYK
Sbjct: 69  QYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYK 128

Query: 169 KGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWC 228
           KGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWC
Sbjct: 129 KGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWC 188

Query: 229 GSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTA 288
           GSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTA
Sbjct: 189 GSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTA 248

Query: 289 KEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGK 348
           KEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGK
Sbjct: 249 KEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGK 308

Query: 349 QANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLS 408
           QANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLS
Sbjct: 309 QANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLS 368

Query: 409 YLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQF 468
           YLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQF
Sbjct: 369 YLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQF 428

Query: 469 YGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQ 528
           YGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQ
Sbjct: 429 YGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQ 488

Query: 529 GKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGAL 588
           GKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGAL
Sbjct: 489 GKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGAL 548

Query: 589 NSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGK 648
           NSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGK
Sbjct: 549 NSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGK 608

Query: 649 AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF 708
           AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF
Sbjct: 609 AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF 668

Query: 709 VWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 768
           VWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW
Sbjct: 669 VWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 728

Query: 769 SVDPLDRAMAELAA 782
           SVDPLDRAMAELAA
Sbjct: 729 SVDPLDRAMAELAA 742


>gi|38044288 gelsolin isoform b [Homo sapiens]
          Length = 731

 Score = 1485 bits (3844), Expect = 0.0
 Identities = 731/731 (100%), Positives = 731/731 (100%)

Query: 52  MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 111
           MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD
Sbjct: 1   MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 60

Query: 112 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 171
           LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG
Sbjct: 61  LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 120

Query: 172 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 231
           VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN
Sbjct: 121 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 180

Query: 232 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 291
           SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED
Sbjct: 181 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 240

Query: 292 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 351
           AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN
Sbjct: 241 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 300

Query: 352 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 411
           TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS
Sbjct: 301 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 360

Query: 412 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 471
           SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG
Sbjct: 361 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 420

Query: 472 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 531
           DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE
Sbjct: 421 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 480

Query: 532 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 591
           PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN
Sbjct: 481 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 540

Query: 592 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 651
           DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY
Sbjct: 541 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 600

Query: 652 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 711
           RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV
Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660

Query: 712 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 771
           GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD
Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 720

Query: 772 PLDRAMAELAA 782
           PLDRAMAELAA
Sbjct: 721 PLDRAMAELAA 731


>gi|189083778 gelsolin isoform b [Homo sapiens]
          Length = 731

 Score = 1485 bits (3844), Expect = 0.0
 Identities = 731/731 (100%), Positives = 731/731 (100%)

Query: 52  MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 111
           MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD
Sbjct: 1   MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 60

Query: 112 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 171
           LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG
Sbjct: 61  LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 120

Query: 172 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 231
           VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN
Sbjct: 121 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 180

Query: 232 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 291
           SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED
Sbjct: 181 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 240

Query: 292 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 351
           AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN
Sbjct: 241 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 300

Query: 352 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 411
           TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS
Sbjct: 301 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 360

Query: 412 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 471
           SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG
Sbjct: 361 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 420

Query: 472 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 531
           DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE
Sbjct: 421 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 480

Query: 532 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 591
           PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN
Sbjct: 481 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 540

Query: 592 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 651
           DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY
Sbjct: 541 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 600

Query: 652 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 711
           RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV
Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660

Query: 712 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 771
           GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD
Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 720

Query: 772 PLDRAMAELAA 782
           PLDRAMAELAA
Sbjct: 721 PLDRAMAELAA 731


>gi|189083776 gelsolin isoform b [Homo sapiens]
          Length = 731

 Score = 1485 bits (3844), Expect = 0.0
 Identities = 731/731 (100%), Positives = 731/731 (100%)

Query: 52  MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 111
           MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD
Sbjct: 1   MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 60

Query: 112 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 171
           LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG
Sbjct: 61  LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 120

Query: 172 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 231
           VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN
Sbjct: 121 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 180

Query: 232 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 291
           SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED
Sbjct: 181 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 240

Query: 292 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 351
           AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN
Sbjct: 241 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 300

Query: 352 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 411
           TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS
Sbjct: 301 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 360

Query: 412 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 471
           SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG
Sbjct: 361 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 420

Query: 472 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 531
           DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE
Sbjct: 421 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 480

Query: 532 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 591
           PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN
Sbjct: 481 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 540

Query: 592 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 651
           DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY
Sbjct: 541 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 600

Query: 652 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 711
           RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV
Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660

Query: 712 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 771
           GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD
Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 720

Query: 772 PLDRAMAELAA 782
           PLDRAMAELAA
Sbjct: 721 PLDRAMAELAA 731


>gi|189083774 gelsolin isoform b [Homo sapiens]
          Length = 731

 Score = 1485 bits (3844), Expect = 0.0
 Identities = 731/731 (100%), Positives = 731/731 (100%)

Query: 52  MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 111
           MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD
Sbjct: 1   MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 60

Query: 112 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 171
           LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG
Sbjct: 61  LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 120

Query: 172 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 231
           VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN
Sbjct: 121 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 180

Query: 232 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 291
           SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED
Sbjct: 181 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 240

Query: 292 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 351
           AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN
Sbjct: 241 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 300

Query: 352 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 411
           TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS
Sbjct: 301 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 360

Query: 412 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 471
           SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG
Sbjct: 361 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 420

Query: 472 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 531
           DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE
Sbjct: 421 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 480

Query: 532 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 591
           PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN
Sbjct: 481 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 540

Query: 592 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 651
           DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY
Sbjct: 541 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 600

Query: 652 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 711
           RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV
Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660

Query: 712 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 771
           GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD
Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 720

Query: 772 PLDRAMAELAA 782
           PLDRAMAELAA
Sbjct: 721 PLDRAMAELAA 731


>gi|189083772 gelsolin isoform b [Homo sapiens]
          Length = 731

 Score = 1485 bits (3844), Expect = 0.0
 Identities = 731/731 (100%), Positives = 731/731 (100%)

Query: 52  MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 111
           MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD
Sbjct: 1   MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 60

Query: 112 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 171
           LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG
Sbjct: 61  LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 120

Query: 172 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 231
           VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN
Sbjct: 121 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 180

Query: 232 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 291
           SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED
Sbjct: 181 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 240

Query: 292 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 351
           AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN
Sbjct: 241 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 300

Query: 352 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 411
           TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS
Sbjct: 301 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 360

Query: 412 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 471
           SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG
Sbjct: 361 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 420

Query: 472 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 531
           DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE
Sbjct: 421 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 480

Query: 532 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 591
           PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN
Sbjct: 481 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 540

Query: 592 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 651
           DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY
Sbjct: 541 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 600

Query: 652 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 711
           RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV
Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660

Query: 712 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 771
           GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD
Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 720

Query: 772 PLDRAMAELAA 782
           PLDRAMAELAA
Sbjct: 721 PLDRAMAELAA 731


>gi|162951877 scinderin isoform 1 [Homo sapiens]
          Length = 715

 Score =  915 bits (2366), Expect = 0.0
 Identities = 431/715 (60%), Positives = 547/715 (76%), Gaps = 8/715 (1%)

Query: 56  HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
           H EF +AGK+ GLQ+WR+EK +LVPVP + +GDF+ GDAY++L T +   G   Y LH+W
Sbjct: 7   HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 65

Query: 116 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 175
           LG ECSQDES AAAIFTVQ+DDYL G+ VQ+RE+QG+ES  F+ YFK GLKYK GGVASG
Sbjct: 66  LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125

Query: 176 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 235
             HV+ N++  +RL  VKGRRVVRATEVP+SW+SFN GDCFI+DLG  I+QWCGS+ N+Y
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185

Query: 236 ERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALP-AGTEDTAKEDAAN 294
           ERLKA QV+ GIR NER GR+ + V EEG+EP  +++VLG KP LP  G +D    D +N
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISN 245

Query: 295 RKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEE 354
           RK+AKLY VS+ +G+M V++VA+ENPF+   L SE+CFILDHG   +IFVWKGK AN +E
Sbjct: 246 RKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQE 305

Query: 355 RKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHI 414
           RKAA+KTA +F+ +M+Y K TQ+ VLPEGGETP+FKQFFK+WRD DQ+DG G  Y++  +
Sbjct: 306 RKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKV 365

Query: 415 ANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSY 474
           A ++++PFDA+ LH+S  MAAQH M DDG+G+ +IWR+E + ++ VD  +YG+FYGGD Y
Sbjct: 366 AQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCY 425

Query: 475 IILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAH 534
           IILY Y     +GQIIY WQGA +T+DE+  SA LT QLD  LGG  VQ RV QGKEP H
Sbjct: 426 IILYTY----PRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVH 481

Query: 535 LMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAF 594
           L+SLF  KP+IIYK GTS++GGQ     TRLFQVR N A  TR VEV   A +LNSND F
Sbjct: 482 LLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVF 541

Query: 595 VLKTP-SAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRT 653
           VLK P ++ Y+WVG GAS+ E+ GA+ +  VL+ + +++ EG EP+ FW +LGGK  Y+T
Sbjct: 542 VLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQT 601

Query: 654 SPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGK 713
           SP L+ +  D HPPRL+ CSNK GRFVIEE+PGE  Q+DLA DDVMLLD W+Q+F+W+GK
Sbjct: 602 SPLLETQAED-HPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660

Query: 714 DSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 768
           D+ E EK E+L SAK Y+ETDP+ RD+RTPI ++KQG EPP+F GWFLGWD   W
Sbjct: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715


>gi|194394237 villin 1 [Homo sapiens]
          Length = 827

 Score =  684 bits (1765), Expect = 0.0
 Identities = 361/711 (50%), Positives = 452/711 (63%), Gaps = 14/711 (1%)

Query: 66  PGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDES 125
           PGLQIWR+E   +VPVP++ +G FF GD Y+IL  +     +L YD+HYW+G + S DE 
Sbjct: 17  PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIIL-AIHKTASSLSYDIHYWIGQDSSLDEQ 75

Query: 126 GAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVV 185
           GAAAI+T Q+DD+L GRAVQHREVQG ES  F GYFK GL  +KGGVASG KHV  N   
Sbjct: 76  GAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135

Query: 186 VQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSK 245
           VQRL  VKG+R V A EV +SW+SFN GD F+LDLG  I QW G  S R ERL+   ++K
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195

Query: 246 GIRDNERSGRARVHVSEEGTE------PEAMLQVLGPKPALPAGTEDTAKEDAANRKLAK 299
            IRD ER GR  V V +   E       E M  VLG +  L A   DT  E A    L K
Sbjct: 196 EIRDQERGGRTYVGVVDGENELASPKLMEVMNHVLGKRRELKAAVPDTVVEPALKAAL-K 254

Query: 300 LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAAL 359
           LY VS+  G + V  VA   P  Q  L  EDC+ILD G   KI+VWKGK+AN +E+K A+
Sbjct: 255 LYHVSDSEGNLVVREVATR-PLTQDLLSHEDCYILDQG-GLKIYVWKGKKANEQEKKGAM 312

Query: 360 KTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVER 419
             A +FI    YP  TQV V  +G E+ +F+Q F+ W   ++T GLG ++    +A VE+
Sbjct: 313 SHALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKWTASNRTSGLGKTHTVGSVAKVEQ 372

Query: 420 VPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYN 479
           V FDA ++H    +AAQ  M DDG+G+ Q+WRIE    VPVD    G FYGGD Y++LY 
Sbjct: 373 VKFDATSMHVKPQVAAQQKMVDDGSGEVQVWRIENLELVPVDSKWLGHFYGGDCYLLLYT 432

Query: 480 YRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLF 539
           Y  G +Q  ++Y WQG+Q++QDE+ ASA     LD++  G PVQ RV  GKEP HLMS+F
Sbjct: 433 YLIGEKQHYLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIF 492

Query: 540 GGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTP 599
            G+ M++Y+GGTSR        STRLFQV+   A  T+A EV  +A  LNSND FVLKT 
Sbjct: 493 KGR-MVVYQGGTSRTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQ 551

Query: 600 SAAYLWVGTGASEAEKTGAQELL-RVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLK 658
           S  YLW G G S  E+  A+ +   + R +   V EG EP  FW ALGGKA Y  + RL+
Sbjct: 552 SCCYLWCGKGCSGDEREMAKMVADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRLQ 611

Query: 659 DKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEE 718
           ++ +    PRLF CSNK GRF+  E+P +  Q+DL  DDV LLD WDQVF W+GK + EE
Sbjct: 612 EENL-VITPRLFECSNKTGRFLATEIP-DFNQDDLEEDDVFLLDVWDQVFFWIGKHANEE 669

Query: 719 EKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWS 769
           EK  A T+A+ Y++T P+ RD  TPI VVKQG EPP+F GWFL WD   WS
Sbjct: 670 EKKAAATTAQEYLKTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKWS 720


>gi|17572824 advillin [Homo sapiens]
          Length = 819

 Score =  642 bits (1655), Expect = 0.0
 Identities = 339/718 (47%), Positives = 442/718 (61%), Gaps = 14/718 (1%)

Query: 59  FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGN 118
           F     +PG+ +WR+EK +L  VP + +G+F+ GD YVIL T ++ +  L  D+H+W+G 
Sbjct: 7   FRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVAS-LLSQDIHFWIGK 65

Query: 119 ECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKH 178
           + SQDE   AAI+T QLDDYL G  VQHREVQ  ES TF GYFK G+ YK+GGVASG KH
Sbjct: 66  DSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKH 125

Query: 179 VVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERL 238
           V  N   V+RL  VKG+R +RATEV +SW+SFN GD F+LDLG  I QW G  SN  ERL
Sbjct: 126 VETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERL 185

Query: 239 KATQVSKGIRDNERSGRARVHVSE---EGTEPEAML---QVLGPKPALPAGTEDTAKEDA 292
           KA  ++K IRD ER GRA + V E   E   PE M      LG +  +     D    D 
Sbjct: 186 KAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEII-DQ 244

Query: 293 ANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANT 352
             +    LY +S+ AG ++V+ VA   P  Q  L  +DC+ILD     KI+VWKGK A  
Sbjct: 245 KQKSTIMLYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQSGT-KIYVWKGKGATK 302

Query: 353 EERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSS 412
            E++AA+  A  FI    YP  T V  + +G E+ +FKQ F+ W   DQT GLG ++   
Sbjct: 303 AEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIG 362

Query: 413 HIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGD 472
            IA V +  FD   LHT   +AAQ  M DDG G+ ++WRIE    VPV+   YG FYGGD
Sbjct: 363 KIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGD 422

Query: 473 SYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 532
            Y++LY Y   G+   I+Y WQG  ++QDE+AASA    ++D +  G  VQ RV  G EP
Sbjct: 423 CYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEP 482

Query: 533 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 592
            H M++F GK ++I++GGTSR+G        RLFQ+  N    T+AVEV   A +LNSND
Sbjct: 483 RHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 541

Query: 593 AFVLKTPSAAYLWVGTGASEAEKTGAQELLRVL-RAQPVQVAEGSEPDGFWEALGGKAAY 651
            F+L+T +  YLW G G+S  E+  A+EL  +L       VAEG EP  FW+ LGGK  Y
Sbjct: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPY 601

Query: 652 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 711
               RL+ + +D    RLF CSNK G+FV+ E+  +  Q+DL   DVMLLDTWDQVF+W+
Sbjct: 602 ANDKRLQQEILDVQ-SRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWI 659

Query: 712 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWS 769
           G ++   EK  AL +A++Y+ T P+ RD  TPI ++KQGFEPP F GWFL WD + WS
Sbjct: 660 GAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWS 717


>gi|14916473 scinderin isoform 2 [Homo sapiens]
          Length = 468

 Score =  601 bits (1549), Expect = e-172
 Identities = 281/473 (59%), Positives = 360/473 (76%), Gaps = 6/473 (1%)

Query: 297 LAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERK 356
           +AKLY VS+ +G+M V++VA+ENPF+   L SE+CFILDHG   +IFVWKGK AN +ERK
Sbjct: 1   MAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERK 60

Query: 357 AALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIAN 416
           AA+KTA +F+ +M+Y K TQ+ VLPEGGETP+FKQFFK+WRD DQ+DG G  Y++  +A 
Sbjct: 61  AAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQ 120

Query: 417 VERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYII 476
           ++++PFDA+ LH+S  MAAQH M DDG+G+ +IWR+E + ++ VD  +YG+FYGGD YII
Sbjct: 121 IKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYII 180

Query: 477 LYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLM 536
           LY Y     +GQIIY WQGA +T+DE+  SA LT QLD  LGG  VQ RV QGKEP HL+
Sbjct: 181 LYTY----PRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLL 236

Query: 537 SLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVL 596
           SLF  KP+IIYK GTS++GGQ     TRLFQVR N A  TR VEV   A +LNSND FVL
Sbjct: 237 SLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVL 296

Query: 597 KTP-SAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSP 655
           K P ++ Y+WVG GAS+ E+ GA+ +  VL+ + +++ EG EP+ FW +LGGK  Y+TSP
Sbjct: 297 KLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSP 356

Query: 656 RLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDS 715
            L+ +  D HPPRL+ CSNK GRFVIEE+PGE  Q+DLA DDVMLLD W+Q+F+W+GKD+
Sbjct: 357 LLETQAED-HPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDA 415

Query: 716 QEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 768
            E EK E+L SAK Y+ETDP+ RD+RTPI ++KQG EPP+F GWFLGWD   W
Sbjct: 416 NEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 468



 Score =  135 bits (340), Expect = 1e-31
 Identities = 110/337 (32%), Positives = 155/337 (45%), Gaps = 32/337 (9%)

Query: 68  LQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGA 127
           ++IWRVE    + V  N YG+F+ GD Y+IL T     G + Y    W G   ++DE   
Sbjct: 151 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYP--RGQIIYT---WQGANATRDELTT 205

Query: 128 AAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSG--LKYKKGGVASGFKHVVPNEVV 185
           +A  TVQLD  L G+AVQ R  QG E    L  FK    + YK G    G +   P    
Sbjct: 206 SAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAP---- 261

Query: 186 VQRLFQVKGR--RVVRATEVPVSWESFNNGDCFILDLGNNI-HQWCGSNSNRYERLKATQ 242
             RLFQV+     + R  EV V   S N+ D F+L L  N  + W G  +++ E   A  
Sbjct: 262 PTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEY 321

Query: 243 VSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAG-TEDTAKEDAANRKLAKLY 301
           V+  +       + +    +EG EPE     LG K         +T  ED   R    LY
Sbjct: 322 VASVL-------KCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLETQAEDHPPR----LY 370

Query: 302 KVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKT 361
             SN  G   +  +  E  F Q  L  +D  +LD  +  +IF+W GK AN  E+K +LK+
Sbjct: 371 GCSNKTGRFVIEEIPGE--FTQDDLAEDDVMLLDAWE--QIFIWIGKDANEVEKKESLKS 426

Query: 362 ASDFI--TKMDYPKQTQVSVLPEGGETPLFKQFFKNW 396
           A  ++        K+T + ++ +G E P F  +F  W
Sbjct: 427 AKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 463



 Score = 37.0 bits (84), Expect = 0.071
 Identities = 47/203 (23%), Positives = 79/203 (38%), Gaps = 37/203 (18%)

Query: 195 RRVVRATEVPVSWESFNNGDCFILDLG--NNIHQWCGSNSNRYERLKATQVSKG-IRDNE 251
           R  V A E P S     + +CFILD G    I  W G ++N  ER  A + ++  ++   
Sbjct: 15  RVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMN 74

Query: 252 RSGRARVHVSEEGTEPEAMLQ------------------VLGPKPALPAGTEDTAKEDAA 293
            S   ++ V  EG E     Q                  V      +     D +K  ++
Sbjct: 75  YSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQIKQIPFDASKLHSS 134

Query: 294 NRKLAKLYKVSNGAGTMSV-------SLVADENPFAQGALKSEDCFIL--DHGKDGKIFV 344
            +  A+   V +G+G + +        +  D+N +  G     DC+I+   + +   I+ 
Sbjct: 135 PQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSY--GEFYGGDCYIILYTYPRGQIIYT 192

Query: 345 WKGKQANTEERKAALKTASDFIT 367
           W+G  A  +E      T S F+T
Sbjct: 193 WQGANATRDE-----LTTSAFLT 210


>gi|94721268 villin-like protein [Homo sapiens]
          Length = 856

 Score =  503 bits (1295), Expect = e-142
 Identities = 290/729 (39%), Positives = 414/729 (56%), Gaps = 28/729 (3%)

Query: 63  GKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGN--LQYDLHYWLGNEC 120
           G + GL IW  E   +VPVP   YG+FF    YVIL   Q          DLHYW+G + 
Sbjct: 9   GMQGGLHIWISENRKMVPVPEGAYGNFFEEHCYVILHVPQSPKATQGASSDLHYWVGKQA 68

Query: 121 SQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVV 180
             +  GAA  F  +L D L G+ V HRE QG ES  F  YF+ G+ Y+KGG+AS  KHV 
Sbjct: 69  GAEAQGAAEAFQQRLQDELGGQTVLHREAQGHESDCFCSYFRPGIIYRKGGLASDLKHVE 128

Query: 181 PNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA 240
            N   +QRL  +KGR+ V ATEV +SW SFN GD F+LDLG  + QW G  ++  E+ + 
Sbjct: 129 TNLFNIQRLLHIKGRKHVSATEVELSWNSFNKGDIFLLDLGKMMIQWNGPKTSISEKARG 188

Query: 241 TQVSKGIRDNER-SGRARVHVSEEGTEPEAMLQ----VLGPK-PALPAGT--EDTAKEDA 292
             ++  +RD ER  GRA++ V ++  +   ++Q    VLG +  +L A T  +D  +   
Sbjct: 189 LALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSLRAATPSKDINQLQK 248

Query: 293 ANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANT 352
           AN +L  +Y+     G   V L     P  Q  L+ ED +ILD G   KI+VW+G+ ++ 
Sbjct: 249 ANVRLYHVYE----KGKDLVVLELATPPLTQDLLQEEDFYILDQG-GFKIYVWQGRMSSL 303

Query: 353 EERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDP-DQTDGLGLSYLS 411
           +ERKAA   A  FI    YP  T V V+ +G E+  FKQ F+ W +   +   LG    S
Sbjct: 304 QERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSEKRRRNQKLGGRDKS 363

Query: 412 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 471
            H      V  D   LHT   +AAQ  M DDG+G+ ++W I+  ++ PVDP  +GQ   G
Sbjct: 364 IH------VKLDVGKLHTQPKLAAQLRMVDDGSGKVEVWCIQDLHRQPVDPKRHGQLCAG 417

Query: 472 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 531
           + Y++LY Y+  GR   I+Y WQG Q+T DE+ A      +LD   GG  VQ  V  G E
Sbjct: 418 NCYLVLYTYQRLGRVQYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEHVTMGSE 477

Query: 532 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 591
           P H +++F G+ ++I++      G   + ++TRLFQV+   +  TR +EV  +A +LNS+
Sbjct: 478 PPHFLAIFQGQ-LVIFQERAGHHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSS 536

Query: 592 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVL-RAQPVQVAEGSEPDGFWEALGGKAA 650
           D F+L T S  YLW G G +  ++  A+ ++ V+ R     V EG EP  FWEALGG+A 
Sbjct: 537 DIFLLVTASVCYLWFGKGCNGDQREMARVVVTVISRKNEETVLEGQEPPHFWEALGGRAP 596

Query: 651 YRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVW 710
           Y ++ RL + ++ +  PRLF CS+ +G  V+ EV G   QEDL   D+MLLDTW ++F+W
Sbjct: 597 YPSNKRLPE-EVPSFQPRLFECSSHMGCLVLAEV-GFFSQEDLDKYDIMLLDTWQEIFLW 654

Query: 711 VGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSV 770
           +G+ + E +  EA+   + Y++T PA R   TPI +VKQG EPP+F+GWF  WD   W+ 
Sbjct: 655 LGEAASEWK--EAVAWGQEYLKTHPAGRSPATPIVLVKQGHEPPTFIGWFFTWDPYKWTS 712

Query: 771 DPLDRAMAE 779
            P  + + +
Sbjct: 713 HPSHKEVVD 721


>gi|63252913 gelsolin-like capping protein [Homo sapiens]
          Length = 348

 Score =  342 bits (878), Expect = 6e-94
 Identities = 171/337 (50%), Positives = 230/337 (68%), Gaps = 8/337 (2%)

Query: 64  KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 122
           ++PGL +WRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G + S+
Sbjct: 17  QDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVL-----HNGPEEVSHLHLWIGQQSSR 71

Query: 123 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF-KHVVP 181
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F K    
Sbjct: 72  DEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG 131

Query: 182 NEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKAT 241
               +++L+QVKG++ +RATE  ++W+SFN GDCFILDLG NI  WCG  SN  ER KA 
Sbjct: 132 APAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191

Query: 242 QVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAKL 300
            ++  IRD+ER G+A+V +  +G EP  M+QVLGPKPAL  G  E+    D AN + A L
Sbjct: 192 DLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAAL 251

Query: 301 YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 360
           YKVS+  G M+++ VAD +PFA   L S+DCF+LD+G  GKI++WKG++AN +ER+AAL+
Sbjct: 252 YKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQ 311

Query: 361 TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWR 397
            A  FI++M Y   TQV +LP+G E+P+FKQFFK+W+
Sbjct: 312 VAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348



 Score =  125 bits (314), Expect = 2e-28
 Identities = 100/338 (29%), Positives = 154/338 (45%), Gaps = 36/338 (10%)

Query: 449 IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 508
           +WR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 23  VWRVEKLKPVPVAQENQGVFFSGDSYLVLHN---GPEEVSHLHLWIGQQSSRDEQGACAV 79

Query: 509 LTAQLDEELGGTPVQSRVVQGKEPAHLMSLF--------GGKPMIIYKGGTSREGGQTAP 560
           L   L+  LG  PVQ R VQG E    MS F        GG     +K  T       AP
Sbjct: 80  LAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG------AP 133

Query: 561 AS-TRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQ 619
           A+  +L+QV+       RA E      + N+ D F+L      + W G  ++  E+  A+
Sbjct: 134 AAIKKLYQVKGKK--NIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191

Query: 620 ELLRVLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKD---KKMDAHPPRL 669
           +L   +R       AQ   V +G EP    + LG K A +     +D    K +A    L
Sbjct: 192 DLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAAL 251

Query: 670 FACSNKIGRFVIEEV--PGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALT 725
           +  S+  G+  + +V        E L +DD  +LD     ++++W G+ + E+E+  AL 
Sbjct: 252 YKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQ 311

Query: 726 SAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGW 763
            A+ +I          T + ++ QG E P F  +F  W
Sbjct: 312 VAEGFISR--MQYAPNTQVEILPQGHESPIFKQFFKDW 347


>gi|4503743 flightless I homolog [Homo sapiens]
          Length = 1269

 Score =  259 bits (661), Expect = 9e-69
 Identities = 227/820 (27%), Positives = 362/820 (44%), Gaps = 111/820 (13%)

Query: 34   ASQAGAPQGRVPE-----ARPNSMVVEHPEFLK--AGKEPGLQIWRVEKFDLVPVPTNLY 86
            ++ A AP G+V        +P    +++ EF     G+ PGL IW++E F  V V    +
Sbjct: 463  SADARAPSGKVRRWDQGLEKPR---LDYSEFFTEDVGQLPGLTIWQIENFVPVLVEEAFH 519

Query: 87   GDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQH 146
            G F+  D Y++LKT    +G+L ++++YW+G E + D+   +AI  V L +YL       
Sbjct: 520  GKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTV 579

Query: 147  REVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVS 206
            RE  G ES  FL  F + + Y +GG ASGF + V +   V R+++V G++ ++   VP+ 
Sbjct: 580  REEMGDESEEFLQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLK 638

Query: 207  WESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTE 266
              S +    F+LD G +I+ W G+ +      KA   ++ I  NER G+A + +  +G E
Sbjct: 639  GTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLLVQGQE 698

Query: 267  PEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKLYKVSNGAGTM-------SVSLVADEN 319
                 + LG +   P+  +    ED    +  KLYKV  G G +        +S+   + 
Sbjct: 699  LPEFWEALGGE---PSEIKKHVPEDFWPPQ-PKLYKVGLGLGYLELPQINYKLSVEHKQR 754

Query: 320  P---------FAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMD 370
            P           Q  L +   +ILD   D  +F+W G+++    R AALK   +    + 
Sbjct: 755  PKVELMPRMRLLQSLLDTRCVYILDCWSD--VFIWLGRKSPRLVRAAALKLGQELCGMLH 812

Query: 371  YPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTD----------GLGLS-YLSSHIANVER 419
             P+   VS   EG E  +FK  FKNW D    D            GLS  +       ++
Sbjct: 813  RPRHATVSRSLEGTEAQVFKAKFKNWDDVLTVDYTRNAEAVLQSPGLSGKVKRDAEKKDQ 872

Query: 420  VPFDAATLH------TSTAMAAQ--HGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 471
            +  D   L        S A A Q     ++D  G +  + +EG     +    +G FY  
Sbjct: 873  MKADLTALFLPRQPPMSLAEAEQLMEEWNEDLDGMEG-FVLEGKKFARLPEEEFGHFYTQ 931

Query: 472  DSYIILYNY-----------------RHGGRQGQ-----------------IIYNWQGAQ 497
            D Y+ L  Y                 +  G++G+                 I+Y WQG +
Sbjct: 932  DCYVFLCRYWVPVEYEEEEKKEDKEEKAEGKEGEEATAEAEEKQPEEDFQCIVYFWQGRE 991

Query: 498  -STQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGG 556
             S    +  +  L  + +    G     R+ Q +E    +S F  K  II++G      G
Sbjct: 992  ASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRK-FIIHRGKRKAVQG 1050

Query: 557  QTAPASTRLFQVRAN-SAGATRAVEVLPKAGALNSNDAFVLKTP-------SAAYLWVGT 608
               P+   L+Q+R N SA  TR +++   +  LNS   F+LK P          Y WVG 
Sbjct: 1051 AQQPS---LYQIRTNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDNQGIVYAWVGR 1107

Query: 609  GASEAEKTGAQELLRVL---RAQPVQVAEGSEPDG-FWEALGGKAAYRTSPRLKDKKMDA 664
             +   E   A+++L  +         + EG EP+  FW  +G +  Y       D +   
Sbjct: 1108 ASDPDEAKLAEDILNTMFDTSYSKQVINEGEEPENFFWVGIGAQKPYD-----DDAEYMK 1162

Query: 665  HPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEAL 724
            H  RLF CSN+ G F + E   +  Q+DLA DD+MLLD   +V++WVG  + + E   +L
Sbjct: 1163 H-TRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWVGTQTSQVEIKLSL 1221

Query: 725  TSAKRYIE-TDPANRDRRTPITVVKQGFEPPSFVGWFLGW 763
             + + YI+       +R   + +V++G E  +F   F  W
Sbjct: 1222 KACQVYIQHMRSKEHERPRRLRLVRKGNEQHAFTRCFHAW 1261



 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 95/348 (27%), Positives = 141/348 (40%), Gaps = 41/348 (11%)

Query: 449 IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRH-GGRQGQIIYNWQGAQSTQDEVAASA 507
           IW+IE    V V+ A +G+FY  D YI+L  +    G     IY W G ++T D+ A SA
Sbjct: 503 IWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSA 562

Query: 508 ILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPAS---TR 564
           I    L   LG      R   G E    + +F     I Y  G +  G  T   +   TR
Sbjct: 563 IHAVNLRNYLGAECRTVREEMGDESEEFLQVFDND--ISYIEGGTASGFYTVEDTHYVTR 620

Query: 565 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 624
           +++V          V +  K  +L+    F+L      Y+W G  A+ +  T A+     
Sbjct: 621 MYRVYGKKNIKLEPVPL--KGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEK 678

Query: 625 L-------RAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMDAHPP--RLFACSNK 675
           +       +A+   + +G E   FWEALGG+     S   K    D  PP  +L+     
Sbjct: 679 INKNERKGKAEITLLVQGQELPEFWEALGGEP----SEIKKHVPEDFWPPQPKLYKVGLG 734

Query: 676 IG-----------------RFVIEEVPG-ELMQEDLATDDVMLLDTWDQVFVWVGKDSQE 717
           +G                 R  +E +P   L+Q  L T  V +LD W  VF+W+G+ S  
Sbjct: 735 LGYLELPQINYKLSVEHKQRPKVELMPRMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPR 794

Query: 718 EEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 765
             +  AL   +        +R R   ++   +G E   F   F  WDD
Sbjct: 795 LVRAAALKLGQEL--CGMLHRPRHATVSRSLEGTEAQVFKAKFKNWDD 840


>gi|150417973 supervillin isoform 2 [Homo sapiens]
          Length = 2214

 Score =  139 bits (349), Expect = 1e-32
 Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)

Query: 189  LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 248
            L Q+KGRR V+   V     + N+GDCF+L   +    W G  +N  E+ KA++++  I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504

Query: 249  DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 299
                 G    ++   EEG            ++LG + +  +  +    E  +AA  +   
Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564

Query: 300  LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 355
            +Y++      M   LV D++ + +      L+ ++  + D G +  ++VW GK+    +R
Sbjct: 1565 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1616

Query: 356  KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 390
            K A + A              I  +D        P++ Q          L E  ET LFK
Sbjct: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676

Query: 391  QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 437
            + F +W +  +++      L+ H            +  +  +P   A T+     +   +
Sbjct: 1677 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736

Query: 438  GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 480
            G+ + G  ++Q         +W I   +   +   + GQF+ GD+Y++ + +        
Sbjct: 1737 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1795

Query: 481  --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 532
                    R  G++  + + WQG  ST  E   SA++T +LDEE G    Q +V+QGKEP
Sbjct: 1796 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1852

Query: 533  AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 592
               +  F G  M+++ G    E  +   +  RL+ VR         +EV     +L S  
Sbjct: 1853 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1910

Query: 593  AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 636
            + V+   + A  YLW G  A +  ++ G     ++    P++               EGS
Sbjct: 1911 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1970

Query: 637  EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 683
            EP GFW+ALG +        L+D       PRLF  S+  G F             V+  
Sbjct: 1971 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 2030

Query: 684  VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 733
            +P   +QEDL +     + L+D   +V++W G    E + T +      +  K  +ET  
Sbjct: 2031 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 2088

Query: 734  ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 764
                  N  +  P + ++  G EP +F   F  W+
Sbjct: 2089 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 2123



 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)

Query: 68   LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 113
            + +W + +FD   +P    G F  GDAYV+     V    G+ Q   H            
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813

Query: 114  -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 172
             +W G   +  E G +A+ TV+LD+    R  Q + +QG E   FL  F+ G+      V
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1865

Query: 173  ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 227
             SG +      V  + RL+ V+G   V     EV     S  +    ++   N   I+ W
Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925

Query: 228  CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 280
             G  +  + +      +  I++          S +  +H  +EG+EP      LG +   
Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1982

Query: 281  PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 330
                 D   +D  +   A +L+ +S+ +G  + +          V    PF Q  L S  
Sbjct: 1983 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 2042

Query: 331  ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 375
                F++D+  +  +++W+G            +     +RK+A++T   +    +  K  
Sbjct: 2043 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 2100

Query: 376  QVSVLPEGGETPL-FKQFFKNW 396
              S L   G  PL F   F +W
Sbjct: 2101 PKSYLIHAGLEPLTFTNMFPSW 2122


>gi|150417971 supervillin isoform 1 [Homo sapiens]
          Length = 1788

 Score =  139 bits (349), Expect = 1e-32
 Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)

Query: 189  LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 248
            L Q+KGRR V+   V     + N+GDCF+L   +    W G  +N  E+ KA++++  I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078

Query: 249  DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 299
                 G    ++   EEG            ++LG + +  +  +    E  +AA  +   
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138

Query: 300  LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 355
            +Y++      M   LV D++ + +      L+ ++  + D G +  ++VW GK+    +R
Sbjct: 1139 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1190

Query: 356  KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 390
            K A + A              I  +D        P++ Q          L E  ET LFK
Sbjct: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250

Query: 391  QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 437
            + F +W +  +++      L+ H            +  +  +P   A T+     +   +
Sbjct: 1251 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310

Query: 438  GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 480
            G+ + G  ++Q         +W I   +   +   + GQF+ GD+Y++ + +        
Sbjct: 1311 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1369

Query: 481  --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 532
                    R  G++  + + WQG  ST  E   SA++T +LDEE G    Q +V+QGKEP
Sbjct: 1370 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1426

Query: 533  AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 592
               +  F G  M+++ G    E  +   +  RL+ VR         +EV     +L S  
Sbjct: 1427 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1484

Query: 593  AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 636
            + V+   + A  YLW G  A +  ++ G     ++    P++               EGS
Sbjct: 1485 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1544

Query: 637  EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 683
            EP GFW+ALG +        L+D       PRLF  S+  G F             V+  
Sbjct: 1545 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 1604

Query: 684  VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 733
            +P   +QEDL +     + L+D   +V++W G    E + T +      +  K  +ET  
Sbjct: 1605 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 1662

Query: 734  ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 764
                  N  +  P + ++  G EP +F   F  W+
Sbjct: 1663 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 1697



 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)

Query: 68   LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 113
            + +W + +FD   +P    G F  GDAYV+     V    G+ Q   H            
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387

Query: 114  -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 172
             +W G   +  E G +A+ TV+LD+    R  Q + +QG E   FL  F+ G+      V
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1439

Query: 173  ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 227
             SG +      V  + RL+ V+G   V     EV     S  +    ++   N   I+ W
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499

Query: 228  CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 280
             G  +  + +      +  I++          S +  +H  +EG+EP      LG +   
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1556

Query: 281  PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 330
                 D   +D  +   A +L+ +S+ +G  + +          V    PF Q  L S  
Sbjct: 1557 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 1616

Query: 331  ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 375
                F++D+  +  +++W+G            +     +RK+A++T   +    +  K  
Sbjct: 1617 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 1674

Query: 376  QVSVLPEGGETPL-FKQFFKNW 396
              S L   G  PL F   F +W
Sbjct: 1675 PKSYLIHAGLEPLTFTNMFPSW 1696


>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 19/53 (35%), Positives = 24/53 (45%)

Query: 6   PAPALLCALSLALCALSLPVRAATASRGASQAGAPQGRVPEARPNSMVVEHPE 58
           PAPAL  A + AL A + P  AA A+   + A AP      A   S    H +
Sbjct: 518 PAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQ 570


>gi|139394599 hypermethylated in cancer 2 [Homo sapiens]
          Length = 615

 Score = 31.2 bits (69), Expect = 3.9
 Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 18/114 (15%)

Query: 459 PVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELG 518
           P+ PAT G     D    L + +HG               +    +A  +  +    ELG
Sbjct: 255 PLPPATPGPHLTPDDAAQLSDSQHG---------------SPPAASAPPVANSASYSELG 299

Query: 519 GTPVQSRVVQGKEPAHLMSLF--GGKPMIIYKGGT-SREGGQTAPASTRLFQVR 569
           GTP +   ++G E  HL  L   GG+P    +  T  +E G+  P +   F+ R
Sbjct: 300 GTPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERR 353


>gi|109637761 calpastatin isoform g [Homo sapiens]
          Length = 772

 Score = 30.8 bits (68), Expect = 5.1
 Identities = 36/146 (24%), Positives = 53/146 (36%), Gaps = 18/146 (12%)

Query: 230 SNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAK 289
           S+S      KA  VS+ +       + +       TEPE   Q   PK +LP    DT  
Sbjct: 81  SSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKPK-SLPKQASDTGS 139

Query: 290 EDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGA---LKSEDCFILDHGKDGKIFVWK 346
            DA N+K              +VS  A++ P  +      K +D           I    
Sbjct: 140 NDAHNKK--------------AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAIS 185

Query: 347 GKQANTEERKAALKTASDFITKMDYP 372
           GK  + ++ K +L  A    +K D P
Sbjct: 186 GKPGDKKKEKKSLTPAVPVESKPDKP 211


>gi|239754618 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 109

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 13/75 (17%)

Query: 4   HRPAPALLCALSLALCALSLPVRAATASRGASQAG--APQGRVPEARPNSM-----VVEH 56
           HRP+  ++C +++ L     P++A T   G++Q    A Q R   A P +      +V+ 
Sbjct: 39  HRPSQ-MVCEVTMLL-----PMKAVTRHMGSAQHSMTASQPRTASAMPITCSPMEAIVQR 92

Query: 57  PEFLKAGKEPGLQIW 71
           P  L+  K  G+++W
Sbjct: 93  PRELRTWKAEGIRLW 107


>gi|239754616 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 164

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 13/75 (17%)

Query: 4   HRPAPALLCALSLALCALSLPVRAATASRGASQAG--APQGRVPEARPNSM-----VVEH 56
           HRP+  ++C +++ L     P++A T   G++Q    A Q R   A P +      +V+ 
Sbjct: 94  HRPSQ-MVCEVTMLL-----PMKAVTRHMGSAQHSMTASQPRTASAMPITCSPMEAIVQR 147

Query: 57  PEFLKAGKEPGLQIW 71
           P  L+  K  G+++W
Sbjct: 148 PRELRTWKAEGIRLW 162


>gi|239749171 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 109

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 13/75 (17%)

Query: 4   HRPAPALLCALSLALCALSLPVRAATASRGASQAG--APQGRVPEARPNSM-----VVEH 56
           HRP+  ++C +++ L     P++A T   G++Q    A Q R   A P +      +V+ 
Sbjct: 39  HRPSQ-MVCEVTMLL-----PMKAVTRHMGSAQHSMTASQPRTASAMPITCSPMEAIVQR 92

Query: 57  PEFLKAGKEPGLQIW 71
           P  L+  K  G+++W
Sbjct: 93  PRELRTWKAEGIRLW 107


>gi|239749169 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 164

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 13/75 (17%)

Query: 4   HRPAPALLCALSLALCALSLPVRAATASRGASQAG--APQGRVPEARPNSM-----VVEH 56
           HRP+  ++C +++ L     P++A T   G++Q    A Q R   A P +      +V+ 
Sbjct: 94  HRPSQ-MVCEVTMLL-----PMKAVTRHMGSAQHSMTASQPRTASAMPITCSPMEAIVQR 147

Query: 57  PEFLKAGKEPGLQIW 71
           P  L+  K  G+++W
Sbjct: 148 PRELRTWKAEGIRLW 162


>gi|239743240 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 109

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 13/75 (17%)

Query: 4   HRPAPALLCALSLALCALSLPVRAATASRGASQAG--APQGRVPEARPNSM-----VVEH 56
           HRP+  ++C +++ L     P++A T   G++Q    A Q R   A P +      +V+ 
Sbjct: 39  HRPSQ-MVCEVTMLL-----PMKAVTRHMGSAQHSMTASQPRTASAMPITCSPMEAIVQR 92

Query: 57  PEFLKAGKEPGLQIW 71
           P  L+  K  G+++W
Sbjct: 93  PRELRTWKAEGIRLW 107


>gi|239743238 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 164

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 13/75 (17%)

Query: 4   HRPAPALLCALSLALCALSLPVRAATASRGASQAG--APQGRVPEARPNSM-----VVEH 56
           HRP+  ++C +++ L     P++A T   G++Q    A Q R   A P +      +V+ 
Sbjct: 94  HRPSQ-MVCEVTMLL-----PMKAVTRHMGSAQHSMTASQPRTASAMPITCSPMEAIVQR 147

Query: 57  PEFLKAGKEPGLQIW 71
           P  L+  K  G+++W
Sbjct: 148 PRELRTWKAEGIRLW 162


>gi|239508915 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 109

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 13/75 (17%)

Query: 4   HRPAPALLCALSLALCALSLPVRAATASRGASQAG--APQGRVPEARPNSM-----VVEH 56
           HRP+  ++C +++ L     P++A T   G++Q    A Q R   A P +      +V+ 
Sbjct: 39  HRPSQ-MVCEVTMLL-----PMKAVTRHMGSAQHSMTASQPRTASAMPITCSPMEAIVQR 92

Query: 57  PEFLKAGKEPGLQIW 71
           P  L+  K  G+++W
Sbjct: 93  PRELRTWKAEGIRLW 107


>gi|239508913 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 164

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 13/75 (17%)

Query: 4   HRPAPALLCALSLALCALSLPVRAATASRGASQAG--APQGRVPEARPNSM-----VVEH 56
           HRP+  ++C +++ L     P++A T   G++Q    A Q R   A P +      +V+ 
Sbjct: 94  HRPSQ-MVCEVTMLL-----PMKAVTRHMGSAQHSMTASQPRTASAMPITCSPMEAIVQR 147

Query: 57  PEFLKAGKEPGLQIW 71
           P  L+  K  G+++W
Sbjct: 148 PRELRTWKAEGIRLW 162


>gi|38569394 inhibitor of kappa light polypeptide gene enhancer in
           B-cells, kinase complex-associated protein [Homo
           sapiens]
          Length = 1332

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 15/48 (31%), Positives = 25/48 (52%)

Query: 718 EEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 765
           E+ T  + S    IE DP +R+ +  +++V +GF P    G  +G  D
Sbjct: 29  EQGTVLIGSEHGLIEVDPVSREVKNEVSLVAEGFLPEDGSGRIVGVQD 76


>gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]
          Length = 3639

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 12/73 (16%)

Query: 622  LRVLRAQPVQVAEGSEP--DGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF 679
            LR+     +  A  SE   + +W ALG  AA   SP+LK K + +    L  C+ K  R 
Sbjct: 3576 LRLTSGAEILFAAPSEEQAESWWRALGSTAAQSLSPKLKAKPVSS----LNECTTKDAR- 3630

Query: 680  VIEEVPGELMQED 692
                 PG L++ D
Sbjct: 3631 -----PGCLLRSD 3638


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,331,317
Number of Sequences: 37866
Number of extensions: 1464864
Number of successful extensions: 3817
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3476
Number of HSP's gapped (non-prelim): 54
length of query: 782
length of database: 18,247,518
effective HSP length: 110
effective length of query: 672
effective length of database: 14,082,258
effective search space: 9463277376
effective search space used: 9463277376
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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