Search of human proteins with 4503719

Search of human proteins with 4503719

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503719 fragile histidine triad gene [Homo sapiens]
         (147 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503719 fragile histidine triad gene [Homo sapiens]                303   3e-83
gi|14211923 PKCI-1-related HIT protein [Homo sapiens]                  34   0.038
gi|4885413 histidine triad nucleotide binding protein 1 [Homo sa...    33   0.066
gi|189217863 histidine triad nucleotide binding protein 3 [Homo ...    30   0.72 
gi|109637769 calpastatin isoform k [Homo sapiens]                      29   1.2  
gi|109637763 calpastatin isoform h [Homo sapiens]                      29   1.2  
gi|109637757 calpastatin isoform e [Homo sapiens]                      29   1.2  
gi|27765085 calpastatin isoform b [Homo sapiens]                       29   1.2  
gi|109637765 calpastatin isoform i [Homo sapiens]                      29   1.6  
gi|109637753 calpastatin isoform a [Homo sapiens]                      29   1.6  
gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo ...    28   2.8  
gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo sap...    28   2.8  
gi|68509270 transcriptional adaptor 2-like isoform a [Homo sapiens]    28   3.6  
gi|68509268 transcriptional adaptor 2-like isoform b [Homo sapiens]    27   4.7  
gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD prote...    27   8.0  
gi|40217847 activating signal cointegrator 1 complex subunit 3-l...    27   8.0  

>gi|4503719 fragile histidine triad gene [Homo sapiens]
          Length = 147

 Score =  303 bits (776), Expect = 3e-83
 Identities = 147/147 (100%), Positives = 147/147 (100%)

Query: 1   MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQ 60
           MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQ
Sbjct: 1   MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQ 60

Query: 61  TTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKH 120
           TTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKH
Sbjct: 61  TTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKH 120

Query: 121 DKEDFPASWRSEEEMAAEAAALRVYFQ 147
           DKEDFPASWRSEEEMAAEAAALRVYFQ
Sbjct: 121 DKEDFPASWRSEEEMAAEAAALRVYFQ 147


>gi|14211923 PKCI-1-related HIT protein [Homo sapiens]
          Length = 163

 Score = 34.3 bits (77), Expect = 0.038
 Identities = 19/71 (26%), Positives = 28/71 (39%)

Query: 30  PVVPGHVLVCPLRPVERFHDLRPDEVADLFQTTQRVGTVVEKHFHGTSLTFSMQDGPEAG 89
           P  P H LV P +P+ R      ++   L           +    G      + DG    
Sbjct: 83  PQAPVHFLVIPKKPIPRISQAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVINDGKLGA 142

Query: 90  QTVKHVHVHVL 100
           Q+V H+H+HVL
Sbjct: 143 QSVYHLHIHVL 153


>gi|4885413 histidine triad nucleotide binding protein 1 [Homo
           sapiens]
          Length = 126

 Score = 33.5 bits (75), Expect = 0.066
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 6/100 (6%)

Query: 5   FGQHLIK--PSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQTT 62
           FG+ + K  P+ +  + +   A  +  P  P H LV P + + +   +  D+   L    
Sbjct: 19  FGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQI-SVAEDDDESLLGHL 77

Query: 63  QRVGTVVEKHFHGTSLTFSM--QDGPEAGQTVKHVHVHVL 100
             VG        G +  + M   +G + GQ+V HVH+HVL
Sbjct: 78  MIVGKKCAADL-GLNKGYRMVVNEGSDGGQSVYHVHLHVL 116


>gi|189217863 histidine triad nucleotide binding protein 3 [Homo
           sapiens]
          Length = 182

 Score = 30.0 bits (66), Expect = 0.72
 Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 2/73 (2%)

Query: 29  KPVVPGHVLVCPLRPVERFHDLRPDEVADLFQTTQRVG-TVVEKHFHGTSLTFSMQDGPE 87
           KP    H LV P + +     LR D+V +L +    VG T++E++         M     
Sbjct: 78  KPAATHHYLVVPKKHIGNCRTLRKDQV-ELVENMVTVGKTILERNNFTDFTNVRMGFHMP 136

Query: 88  AGQTVKHVHVHVL 100
              ++ H+H+HVL
Sbjct: 137 PFCSISHLHLHVL 149


>gi|109637769 calpastatin isoform k [Homo sapiens]
          Length = 673

 Score = 29.3 bits (64), Expect = 1.2
 Identities = 18/71 (25%), Positives = 31/71 (43%)

Query: 62  TQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHD 121
           T+ V T  EK    T L+   +   + G+  +H     LP++A D   ND+  ++     
Sbjct: 6   TKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRS 65

Query: 122 KEDFPASWRSE 132
            E  P+   +E
Sbjct: 66  AEQQPSEKSTE 76


>gi|109637763 calpastatin isoform h [Homo sapiens]
          Length = 769

 Score = 29.3 bits (64), Expect = 1.2
 Identities = 18/71 (25%), Positives = 31/71 (43%)

Query: 62  TQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHD 121
           T+ V T  EK    T L+   +   + G+  +H     LP++A D   ND+  ++     
Sbjct: 89  TKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRS 148

Query: 122 KEDFPASWRSE 132
            E  P+   +E
Sbjct: 149 AEQQPSEKSTE 159


>gi|109637757 calpastatin isoform e [Homo sapiens]
          Length = 756

 Score = 29.3 bits (64), Expect = 1.2
 Identities = 18/71 (25%), Positives = 31/71 (43%)

Query: 62  TQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHD 121
           T+ V T  EK    T L+   +   + G+  +H     LP++A D   ND+  ++     
Sbjct: 89  TKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRS 148

Query: 122 KEDFPASWRSE 132
            E  P+   +E
Sbjct: 149 AEQQPSEKSTE 159


>gi|27765085 calpastatin isoform b [Homo sapiens]
          Length = 686

 Score = 29.3 bits (64), Expect = 1.2
 Identities = 18/71 (25%), Positives = 31/71 (43%)

Query: 62  TQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHD 121
           T+ V T  EK    T L+   +   + G+  +H     LP++A D   ND+  ++     
Sbjct: 6   TKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRS 65

Query: 122 KEDFPASWRSE 132
            E  P+   +E
Sbjct: 66  AEQQPSEKSTE 76


>gi|109637765 calpastatin isoform i [Homo sapiens]
          Length = 708

 Score = 28.9 bits (63), Expect = 1.6
 Identities = 18/70 (25%), Positives = 30/70 (42%)

Query: 63  QRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHDK 122
           Q V T  EK    T L+   +   + G+  +H     LP++A D   ND+  ++      
Sbjct: 29  QAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSA 88

Query: 123 EDFPASWRSE 132
           E  P+   +E
Sbjct: 89  EQQPSEKSTE 98


>gi|109637753 calpastatin isoform a [Homo sapiens]
          Length = 791

 Score = 28.9 bits (63), Expect = 1.6
 Identities = 18/70 (25%), Positives = 30/70 (42%)

Query: 63  QRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHDK 122
           Q V T  EK    T L+   +   + G+  +H     LP++A D   ND+  ++      
Sbjct: 112 QAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSA 171

Query: 123 EDFPASWRSE 132
           E  P+   +E
Sbjct: 172 EQQPSEKSTE 181


>gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo
           sapiens]
          Length = 1246

 Score = 28.1 bits (61), Expect = 2.8
 Identities = 33/123 (26%), Positives = 47/123 (38%), Gaps = 21/123 (17%)

Query: 18  KTE--LSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQTTQRVGTVVEKHFHG 75
           KTE  L+F  +   P +P  ++       E   +   DE  D+   T    +        
Sbjct: 153 KTEDFLTFLCLRGSPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNASS-------- 204

Query: 76  TSLTFSMQDGPEAGQTVKHVH-VHVLPRKAGDFHRNDSIYEELQKH-DKEDFPASWRSEE 133
                S Q  P  G+T KHVH  HV    +    R+    E +QKH  KE  PA  +  +
Sbjct: 205 -----SCQSTPRKGKTHKHVHNGHVFNGSS----RSTREKEPVQKHKSKEATPAKEKHSD 255

Query: 134 EMA 136
             A
Sbjct: 256 HRA 258


>gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo
           sapiens]
          Length = 558

 Score = 28.1 bits (61), Expect = 2.8
 Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 76  TSLTFSMQDGPEAGQTVKHVHVHVLPRKAGD--FHRNDSIYEELQKHDKEDFP 126
           TS++ S+Q      Q +K   + +    A D   +  DSIY+E+QK  +E+ P
Sbjct: 39  TSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDSIYDEMQKKKEENNP 91


>gi|68509270 transcriptional adaptor 2-like isoform a [Homo sapiens]
          Length = 443

 Score = 27.7 bits (60), Expect = 3.6
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 6/81 (7%)

Query: 8   HLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQTTQRVGT 67
           H +K +VV +          RK ++  H L+  LR  +      P EV DL++T +R   
Sbjct: 201 HALKMAVVDIYHSRLKERQRRKKIIRDHGLI-NLRKFQLMERRYPKEVQDLYETMRRFAR 259

Query: 68  VV-----EKHFHGTSLTFSMQ 83
           +V     +K     +L F ++
Sbjct: 260 IVGPVEHDKFIESHALEFELR 280


>gi|68509268 transcriptional adaptor 2-like isoform b [Homo sapiens]
          Length = 305

 Score = 27.3 bits (59), Expect = 4.7
 Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 1/62 (1%)

Query: 8   HLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQTTQRVGT 67
           H +K +VV +          RK ++  H L+  LR  +      P EV DL++T +R   
Sbjct: 201 HALKMAVVDIYHSRLKERQRRKKIIRDHGLI-NLRKFQLMERRYPKEVQDLYETMRRFAR 259

Query: 68  VV 69
           +V
Sbjct: 260 IV 261


>gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD protein,
           partial [Homo sapiens]
          Length = 1700

 Score = 26.6 bits (57), Expect = 8.0
 Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 15/105 (14%)

Query: 43  PVERFHDLRPDEVADLFQTTQRVGTVVEKHFH-GTSLTFSMQDGPEAGQTVKHVHVHVLP 101
           P ER +DL  +E+ +L +   ++G  + K+ H    L  S+   P    T+K V + + P
Sbjct: 713 PFERLYDLNHNEIGELIR-MPKMGKTIHKYVHLFPKLELSVHLQPITRSTLK-VELTITP 770

Query: 102 RKAGDFHRNDSIYEELQKHDKEDFPASWRSEEEMAAEAAALRVYF 146
               DF  ++ ++   +        A W   E++ +E      YF
Sbjct: 771 ----DFQWDEKVHGSSE--------AFWILVEDVDSEVILHHEYF 803


>gi|40217847 activating signal cointegrator 1 complex subunit 3-like 1
            [Homo sapiens]
          Length = 2136

 Score = 26.6 bits (57), Expect = 8.0
 Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 15/105 (14%)

Query: 43   PVERFHDLRPDEVADLFQTTQRVGTVVEKHFH-GTSLTFSMQDGPEAGQTVKHVHVHVLP 101
            P ER +DL  +E+ +L +   ++G  + K+ H    L  S+   P    T+K V + + P
Sbjct: 1149 PFERLYDLNHNEIGELIR-MPKMGKTIHKYVHLFPKLELSVHLQPITRSTLK-VELTITP 1206

Query: 102  RKAGDFHRNDSIYEELQKHDKEDFPASWRSEEEMAAEAAALRVYF 146
                DF  ++ ++   +        A W   E++ +E      YF
Sbjct: 1207 ----DFQWDEKVHGSSE--------AFWILVEDVDSEVILHHEYF 1239


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,932,025
Number of Sequences: 37866
Number of extensions: 252353
Number of successful extensions: 545
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 536
Number of HSP's gapped (non-prelim): 16
length of query: 147
length of database: 18,247,518
effective HSP length: 93
effective length of query: 54
effective length of database: 14,725,980
effective search space: 795202920
effective search space used: 795202920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.