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Search of human proteins with 4503183
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503183 cytochrome b-5 isoform 2 [Homo sapiens]
(98 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503183 cytochrome b-5 isoform 2 [Homo sapiens] 207 1e-54
gi|41281768 cytochrome b-5 isoform 1 [Homo sapiens] 205 7e-54
gi|83921614 cytochrome b5 outer mitochondrial membrane precursor... 119 7e-28
gi|4758334 fatty acid desaturase 2 [Homo sapiens] 66 5e-12
gi|84875541 cytochrome b5 reductase 4 [Homo sapiens] 59 6e-10
gi|214831730 fatty acid desaturase 1 [Homo sapiens] 57 2e-09
gi|205360949 fatty acid 2-hydroxylase [Homo sapiens] 54 2e-08
gi|74099704 sulfite oxidase [Homo sapiens] 54 3e-08
gi|74099702 sulfite oxidase [Homo sapiens] 54 3e-08
gi|74099694 sulfite oxidase [Homo sapiens] 54 3e-08
gi|13375616 fatty acid desaturase 3 [Homo sapiens] 53 5e-08
gi|126032348 hect domain and RLD 2 [Homo sapiens] 44 3e-05
gi|40255060 cytochrome b5 domain containing 1 [Homo sapiens] 36 0.006
gi|156104862 ankyrin repeat domain 38 [Homo sapiens] 30 0.41
gi|4501879 acrosomal vesicle protein 1 isoform a precursor [Homo... 29 0.70
gi|9955927 acrosomal vesicle protein 1 isoform b precursor [Homo... 29 0.70
gi|41281996 HEAT repeat containing 3 [Homo sapiens] 28 1.6
gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo ... 28 2.1
gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sa... 28 2.1
gi|4758876 poly(A) binding protein, nuclear 1 [Homo sapiens] 27 4.6
gi|44955929 calmodulin regulated spectrin-associated protein 1-l... 27 4.6
gi|42718015 retinoblastoma binding protein 8 isoform a [Homo sap... 26 6.0
gi|4506441 retinoblastoma binding protein 8 isoform a [Homo sapi... 26 6.0
gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Ho... 26 6.0
gi|118582286 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase... 26 7.8
gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens] 26 7.8
>gi|4503183 cytochrome b-5 isoform 2 [Homo sapiens]
Length = 98
Score = 207 bits (528), Expect = 1e-54
Identities = 98/98 (100%), Positives = 98/98 (100%)
Query: 1 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT 60
MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT
Sbjct: 1 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT 60
Query: 61 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPEP 98
ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPEP
Sbjct: 61 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPEP 98
>gi|41281768 cytochrome b-5 isoform 1 [Homo sapiens]
Length = 134
Score = 205 bits (521), Expect = 7e-54
Identities = 97/97 (100%), Positives = 97/97 (100%)
Query: 1 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT 60
MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT
Sbjct: 1 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT 60
Query: 61 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPE 97
ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPE
Sbjct: 61 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPE 97
>gi|83921614 cytochrome b5 outer mitochondrial membrane precursor
[Homo sapiens]
Length = 150
Score = 119 bits (297), Expect = 7e-28
Identities = 52/86 (60%), Positives = 68/86 (79%)
Query: 3 EQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATEN 62
++ + +V YY LEE+ K N K WL++H +VYD+T+FL EHPGGEEVL EQAG DA+E+
Sbjct: 18 QEVETSVTYYRLEEVAKRNSLKELWLVIHGRVYDVTRFLNEHPGGEEVLLEQAGVDASES 77
Query: 63 FEDVGHSTDAREMSKTFIIGELHPDD 88
FEDVGHS+DAREM K + IG++HP D
Sbjct: 78 FEDVGHSSDAREMLKQYYIGDIHPSD 103
>gi|4758334 fatty acid desaturase 2 [Homo sapiens]
Length = 444
Score = 66.2 bits (160), Expect = 5e-12
Identities = 33/88 (37%), Positives = 52/88 (59%), Gaps = 1/88 (1%)
Query: 2 AEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATE 61
A + + +V ++ EEIQKHN WL++ KVY++TK+ +HPGG+ V+ AG DAT+
Sbjct: 11 AAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVIGHYAGEDATD 70
Query: 62 NFEDVGHSTD-AREMSKTFIIGELHPDD 88
F + + K +IGEL P++
Sbjct: 71 AFRAFHPDLEFVGKFLKPLLIGELAPEE 98
>gi|84875541 cytochrome b5 reductase 4 [Homo sapiens]
Length = 521
Score = 59.3 bits (142), Expect = 6e-10
Identities = 26/72 (36%), Positives = 41/72 (56%)
Query: 13 TLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDA 72
T EE++KHN W+ + VY+++ ++E HPGGE+ L AG D TE F+ V +
Sbjct: 58 TEEELKKHNKKDDCWICIRGFVYNVSPYMEYHPGGEDELMRAAGSDGTELFDQVHRWVNY 117
Query: 73 REMSKTFIIGEL 84
M K ++G +
Sbjct: 118 ESMLKECLVGRM 129
>gi|214831730 fatty acid desaturase 1 [Homo sapiens]
Length = 501
Score = 57.4 bits (137), Expect = 2e-09
Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 4/89 (4%)
Query: 10 KYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHS 69
+Y+T +E+ + + + WL++ KVY++++F HPGG V+ AG DAT+ F +
Sbjct: 75 RYFTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGSRVISHYAGQDATDPFVAFHIN 134
Query: 70 TD-AREMSKTFIIGELHPDD---RPKLNK 94
++ + +IGEL P+ P NK
Sbjct: 135 KGLVKKYMNSLLIGELSPEQPSFEPTKNK 163
>gi|205360949 fatty acid 2-hydroxylase [Homo sapiens]
Length = 372
Score = 54.3 bits (129), Expect = 2e-08
Identities = 25/87 (28%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Query: 12 YTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDV--GHS 69
++ E+Q+ + + W+ ++YDL+ F+ HPGGE++LR +AG D + + + HS
Sbjct: 11 FSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISADLDGPPHRHS 70
Query: 70 TDAREMSKTFIIGELHPDDRPKLNKPP 96
+AR + + +GEL + + + P
Sbjct: 71 ANARRWLEQYYVGELRGEQQGSMENEP 97
>gi|74099704 sulfite oxidase [Homo sapiens]
Length = 545
Score = 53.5 bits (127), Expect = 3e-08
Identities = 29/88 (32%), Positives = 49/88 (55%), Gaps = 3/88 (3%)
Query: 5 SDEAVKYYTLEEIQKHNHSKS-TWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENF 63
+ E+ YT EE+ H ++ W+ L +V+D+T+F++ HPGG L AGG +
Sbjct: 78 AQESTHIYTKEEVSSHTSPETGIWVTLGSEVFDVTEFVDLHPGGPSKLMLAAGGPLEPFW 137
Query: 64 E--DVGHSTDAREMSKTFIIGELHPDDR 89
V + + RE+ + IGEL+P+D+
Sbjct: 138 ALYAVHNQSHVRELLAQYKIGELNPEDK 165
>gi|74099702 sulfite oxidase [Homo sapiens]
Length = 545
Score = 53.5 bits (127), Expect = 3e-08
Identities = 29/88 (32%), Positives = 49/88 (55%), Gaps = 3/88 (3%)
Query: 5 SDEAVKYYTLEEIQKHNHSKS-TWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENF 63
+ E+ YT EE+ H ++ W+ L +V+D+T+F++ HPGG L AGG +
Sbjct: 78 AQESTHIYTKEEVSSHTSPETGIWVTLGSEVFDVTEFVDLHPGGPSKLMLAAGGPLEPFW 137
Query: 64 E--DVGHSTDAREMSKTFIIGELHPDDR 89
V + + RE+ + IGEL+P+D+
Sbjct: 138 ALYAVHNQSHVRELLAQYKIGELNPEDK 165
>gi|74099694 sulfite oxidase [Homo sapiens]
Length = 545
Score = 53.5 bits (127), Expect = 3e-08
Identities = 29/88 (32%), Positives = 49/88 (55%), Gaps = 3/88 (3%)
Query: 5 SDEAVKYYTLEEIQKHNHSKS-TWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENF 63
+ E+ YT EE+ H ++ W+ L +V+D+T+F++ HPGG L AGG +
Sbjct: 78 AQESTHIYTKEEVSSHTSPETGIWVTLGSEVFDVTEFVDLHPGGPSKLMLAAGGPLEPFW 137
Query: 64 E--DVGHSTDAREMSKTFIIGELHPDDR 89
V + + RE+ + IGEL+P+D+
Sbjct: 138 ALYAVHNQSHVRELLAQYKIGELNPEDK 165
>gi|13375616 fatty acid desaturase 3 [Homo sapiens]
Length = 445
Score = 53.1 bits (126), Expect = 5e-08
Identities = 22/75 (29%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
Query: 15 EEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTD-AR 73
E+I+ H+ WL++ +VYD++++ + HPGG ++ DAT+ F + R
Sbjct: 26 EQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDATDAFRAFHQDLNFVR 85
Query: 74 EMSKTFIIGELHPDD 88
+ + +IGEL P++
Sbjct: 86 KFLQPLLIGELAPEE 100
>gi|126032348 hect domain and RLD 2 [Homo sapiens]
Length = 4834
Score = 43.9 bits (102), Expect = 3e-05
Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 1/85 (1%)
Query: 4 QSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENF 63
+++E V +++ HN W ++ KVYD+ F + G +L + AG D
Sbjct: 1202 RNNEEVTLIRKADLENHNKDGGFWTVIDGKVYDIKDFQTQSLTGNSILAQFAGEDPVVAL 1261
Query: 64 EDVGHSTDAREMSKTFIIGE-LHPD 87
E D RE F +G+ L PD
Sbjct: 1262 EAALQFEDTRESMHAFCVGQYLEPD 1286
>gi|40255060 cytochrome b5 domain containing 1 [Homo sapiens]
Length = 228
Score = 36.2 bits (82), Expect = 0.006
Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 10 KYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGG--EEVLREQAGGDATENFE 64
+Y+T E+ +HN + W+ +VYDLT +E+ G + + E AG D + F+
Sbjct: 18 RYFTPAEVAQHNRPEDLWVSYLGRVYDLTSLAQEYKGNLLLKPIVEVAGQDISHWFD 74
>gi|156104862 ankyrin repeat domain 38 [Homo sapiens]
Length = 995
Score = 30.0 bits (66), Expect = 0.41
Identities = 14/43 (32%), Positives = 22/43 (51%)
Query: 17 IQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDA 59
+Q H+ S + + HH DL + L HP + L ++AG A
Sbjct: 924 LQDHDGSSALMVACHHGNVDLVRLLLAHPACDSSLTDKAGRTA 966
>gi|4501879 acrosomal vesicle protein 1 isoform a precursor [Homo
sapiens]
Length = 265
Score = 29.3 bits (64), Expect = 0.70
Identities = 20/83 (24%), Positives = 30/83 (36%), Gaps = 2/83 (2%)
Query: 13 TLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDA 72
TL E H S + H + + EH GE E A G+ T + G
Sbjct: 64 TLSEHGSSEHGSSKHTVAEHTSGEHAE--SEHASGEPAATEHAEGEHTVGEQPSGEQPSG 121
Query: 73 REMSKTFIIGELHPDDRPKLNKP 95
+S + EL ++P +P
Sbjct: 122 EHLSGEQPLSELESGEQPSDEQP 144
>gi|9955927 acrosomal vesicle protein 1 isoform b precursor [Homo
sapiens]
Length = 246
Score = 29.3 bits (64), Expect = 0.70
Identities = 20/83 (24%), Positives = 30/83 (36%), Gaps = 2/83 (2%)
Query: 13 TLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDA 72
TL E H S + H + + EH GE E A G+ T + G
Sbjct: 64 TLSEHGSSEHGSSKHTVAEHTSGEHAE--SEHASGEPAATEHAEGEHTVGEQPSGEQPSG 121
Query: 73 REMSKTFIIGELHPDDRPKLNKP 95
+S + EL ++P +P
Sbjct: 122 EHLSGEQPLSELESGEQPSDEQP 144
>gi|41281996 HEAT repeat containing 3 [Homo sapiens]
Length = 680
Score = 28.1 bits (61), Expect = 1.6
Identities = 18/52 (34%), Positives = 24/52 (46%)
Query: 38 TKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPDDR 89
T+ L+ EE+L G D E+ E G S R KTF+ L P D+
Sbjct: 300 TQRLKTAAEAEEILENTNGDDLIEDDEMEGISHKRRVRRKTFVSDLLPPTDK 351
>gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo
sapiens]
Length = 460
Score = 27.7 bits (60), Expect = 2.1
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 3/53 (5%)
Query: 44 HPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPP 96
HP G+ V+ G E+FED G ++A +T G+L D L P
Sbjct: 78 HPHGQSVITVIGG---EEHFEDYGEGSEAELSPETLCNGQLGCSDPAFLTPSP 127
>gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo
sapiens]
Length = 756
Score = 27.7 bits (60), Expect = 2.1
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 3/53 (5%)
Query: 44 HPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPP 96
HP G+ V+ G E+FED G ++A +T G+L D L P
Sbjct: 374 HPHGQSVITVIGG---EEHFEDYGEGSEAELSPETLCNGQLGCSDPAFLTPSP 423
>gi|4758876 poly(A) binding protein, nuclear 1 [Homo sapiens]
Length = 306
Score = 26.6 bits (57), Expect = 4.6
Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 5/58 (8%)
Query: 45 PGGEEVLREQAGGDATENFE----DVGHSTDAREMSKTFIIGELHPDDRPKLNKPPEP 98
PG L AGG+A E D G+ ++ E+ ++ E P+ P+ +PP P
Sbjct: 21 PGRRRHLVPGAGGEAGEGAPGGAGDYGNGLESEELEPEELLLEPEPEPEPE-EEPPRP 77
>gi|44955929 calmodulin regulated spectrin-associated protein
1-like 1 [Homo sapiens]
Length = 1478
Score = 26.6 bits (57), Expect = 4.6
Identities = 11/23 (47%), Positives = 15/23 (65%)
Query: 66 VGHSTDAREMSKTFIIGELHPDD 88
+G + D REM KTFI+ + P D
Sbjct: 1 MGDAADPREMRKTFIVPAIKPFD 23
>gi|42718015 retinoblastoma binding protein 8 isoform a [Homo
sapiens]
Length = 897
Score = 26.2 bits (56), Expect = 6.0
Identities = 13/35 (37%), Positives = 19/35 (54%)
Query: 61 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKP 95
ENF +VG + M + +I +L P RPK +P
Sbjct: 849 ENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQP 883
>gi|4506441 retinoblastoma binding protein 8 isoform a [Homo
sapiens]
Length = 897
Score = 26.2 bits (56), Expect = 6.0
Identities = 13/35 (37%), Positives = 19/35 (54%)
Query: 61 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKP 95
ENF +VG + M + +I +L P RPK +P
Sbjct: 849 ENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQP 883
>gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Homo
sapiens]
Length = 3549
Score = 26.2 bits (56), Expect = 6.0
Identities = 16/72 (22%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 7 EAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDV 66
E +K T E++QK + ++ WL ++ +D +E H G ++ +E+ + +
Sbjct: 1472 ENIKTVTQEDVQKGDVKQAVWL-FENRTFD--SIMEAHKGITKMTKEEIPPSDVKTTTWL 1528
Query: 67 GHSTDAREMSKT 78
+T E ++T
Sbjct: 1529 FETTPLHEFNET 1540
>gi|118582286 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
[Homo sapiens]
Length = 471
Score = 25.8 bits (55), Expect = 7.8
Identities = 12/48 (25%), Positives = 25/48 (52%)
Query: 12 YTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDA 59
Y + +Q H S++ + +++ V + +L H E +R + GGD+
Sbjct: 227 YMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDS 274
>gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]
Length = 451
Score = 25.8 bits (55), Expect = 7.8
Identities = 10/27 (37%), Positives = 19/27 (70%), Gaps = 1/27 (3%)
Query: 22 HSKSTWLILHHKVY-DLTKFLEEHPGG 47
H+K T ++ V+ DL +++++HPGG
Sbjct: 183 HTKETLTLVFEYVHTDLCQYMDKHPGG 209
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.131 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,581,240
Number of Sequences: 37866
Number of extensions: 185936
Number of successful extensions: 341
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 315
Number of HSP's gapped (non-prelim): 28
length of query: 98
length of database: 18,247,518
effective HSP length: 69
effective length of query: 29
effective length of database: 15,634,764
effective search space: 453408156
effective search space used: 453408156
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.