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Search of human proteins with 4503123
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503123 connective tissue growth factor [Homo sapiens]
(349 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503123 connective tissue growth factor [Homo sapiens] 762 0.0
gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens] 393 e-109
gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens] 360 1e-99
gi|4507921 WNT1 inducible signaling pathway protein 1 isoform 1 ... 333 2e-91
gi|38202241 WNT1 inducible signaling pathway protein 3 isoform 3... 273 1e-73
gi|4507925 WNT1 inducible signaling pathway protein 3 isoform 1 ... 273 1e-73
gi|4507923 WNT1 inducible signaling pathway protein 2 precursor ... 216 2e-56
gi|18491000 WNT1 inducible signaling pathway protein 1 isoform 2... 165 5e-41
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 55 7e-08
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 55 9e-08
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 54 2e-07
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 54 2e-07
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 53 5e-07
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 53 5e-07
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 53 5e-07
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 53 5e-07
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 53 5e-07
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 51 2e-06
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 51 2e-06
gi|108773804 Fraser syndrome 1 [Homo sapiens] 47 3e-05
gi|5901946 endothelial cell-specific molecule 1 isoform a precur... 45 7e-05
gi|40353769 chordin-like 2 [Homo sapiens] 44 2e-04
gi|161019170 mucin 5AC [Homo sapiens] 44 2e-04
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 44 2e-04
gi|56090548 insulin-like growth factor binding protein-like 1 [H... 44 3e-04
gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] 43 4e-04
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa... 43 5e-04
gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens] 43 5e-04
gi|22129776 HtrA serine peptidase 3 [Homo sapiens] 42 6e-04
gi|208022668 endothelial cell-specific molecule 1 isoform b prec... 42 0.001
>gi|4503123 connective tissue growth factor [Homo sapiens]
Length = 349
Score = 762 bits (1968), Expect = 0.0
Identities = 349/349 (100%), Positives = 349/349 (100%)
Query: 1 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVC 60
MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVC
Sbjct: 1 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVC 60
Query: 61 AKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSC 120
AKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSC
Sbjct: 61 AKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSC 120
Query: 121 KYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALA 180
KYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALA
Sbjct: 121 KYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALA 180
Query: 181 AYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVR 240
AYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVR
Sbjct: 181 AYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVR 240
Query: 241 PCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTT 300
PCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTT
Sbjct: 241 PCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTT 300
Query: 301 LPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA 349
LPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA
Sbjct: 301 LPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA 349
>gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]
Length = 357
Score = 393 bits (1010), Expect = e-109
Identities = 173/325 (53%), Positives = 225/325 (69%), Gaps = 4/325 (1%)
Query: 15 VLLALCSRPAVGQNCSGPC--RCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERD 72
+LL L + A Q C C RCP P P C GV VLDGC CC VCA+Q GE C++ +
Sbjct: 21 LLLHLLGQVAATQRCPPQCPGRCPATP-PTCAPGVRAVLDGCSCCLVCARQRGESCSDLE 79
Query: 73 PCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVG 132
PCD GL+CD + + + G+CTA +G C+F G +YRSGE FQ SCK+QCTC DG +G
Sbjct: 80 PCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRSGEKFQPSCKFQCTCRDGQIG 139
Query: 133 CMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALAAYRLEDTFGPDP 192
C+P C +DV LP P+CP PR+V++PG+CCE+W+C ++ ++ G LAAYR E T G +
Sbjct: 140 CVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDSLGGLTLAAYRPEATLGVEV 199
Query: 193 TMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEE-NIK 251
+ NC+ QTTEW+ACSK+CGMG STRVTN N C + KQ+RLCMVRPCE + E+ K
Sbjct: 200 SDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTDK 259
Query: 252 KGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGE 311
KGKKC+RT K K I + CTS+ TY+ +FCGVC+DGRCCTPH T T+ EF+C G+
Sbjct: 260 KGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQ 319
Query: 312 VMKKNMMFIKTCACHYNCPGDNDIF 336
++KK +M I TC CH NCP +N+ F
Sbjct: 320 IVKKPVMVIGTCTCHTNCPKNNEAF 344
>gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
Length = 381
Score = 360 bits (923), Expect = 1e-99
Identities = 175/373 (46%), Positives = 232/373 (62%), Gaps = 40/373 (10%)
Query: 11 VAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTE 70
+A VV L +R A+ C C CP E AP+C GV LV DGCGCC+VCAKQL E C++
Sbjct: 9 LALVVTLLHLTRLALS-TCPAACHCPLE-APKCAPGVGLVRDGCGCCKVCAKQLNEDCSK 66
Query: 71 RDPCDPHKGLFCDFGSPANRKIGVCTAK-DGAPCIFGGTVYRSGESFQSSCKYQCTCLDG 129
PCD KGL C+FG+ + G+C A+ +G PC + +Y++GESFQ +CK+QCTC+DG
Sbjct: 67 TQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDG 126
Query: 130 AVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEP------KDQT---------- 173
AVGC+PLC ++ LP+ CP PR VK+ G+CCEEWVCDE +DQ
Sbjct: 127 AVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFD 186
Query: 174 -------------VVGPALAAYRLEDTFGPDPTMIR-----ANCLVQTTEWSACSKTCGM 215
VG + RL FG +P ++ C+VQTT WS CSKTCG
Sbjct: 187 ASEVELTRNNELIAVGKGSSLKRLP-VFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGT 245
Query: 216 GISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTS 275
GISTRVTNDN CRL K++R+C VRPC + ++KKGKKC +T K +P++F +GC S
Sbjct: 246 GISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLS 305
Query: 276 MKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDI 335
+K YR K+CG C DGRCCTP T T+ + F+C DGE KN+M I++C C+YNCP N+
Sbjct: 306 VKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEA 365
Query: 336 FESLYYRKMYGDM 348
Y +++ D+
Sbjct: 366 AFPFY--RLFNDI 376
>gi|4507921 WNT1 inducible signaling pathway protein 1 isoform 1
precursor [Homo sapiens]
Length = 367
Score = 333 bits (853), Expect = 2e-91
Identities = 158/343 (46%), Positives = 210/343 (61%), Gaps = 14/343 (4%)
Query: 2 TAASMGPVRVAFVV--LLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRV 59
TA S P + F L SRP Q C PC CP P PRCP GVSL+ DGC CC++
Sbjct: 23 TALSPAPTTMDFTPAPLEDTSSRP---QFCKWPCECPPSP-PRCPLGVSLITDGCECCKM 78
Query: 60 CAKQLGELCTERDPCDPHKGLFCDFGSPANR-KIGVCTAKDGAPCIFGGTVYRSGESFQS 118
CA+QLG+ CTE CDPH+GL+CD+ R IGVC G C+ G Y +G+SFQ
Sbjct: 79 CAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCAQVVGVGCVLDGVRYNNGQSFQP 138
Query: 119 SCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPA 178
+CKY CTC+DGAVGC PLC + VR P CP PRRV +PG CCE+WVC++ + P
Sbjct: 139 NCKYNCTCIDGAVGCTPLC-LRVRPPRLWCPHPRRVSIPGHCCEQWVCEDDAKR----PR 193
Query: 179 LAAYRLEDTFGP--DPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRL 236
A R F + NC+ T+ WS CS +CG+G+STR++N NA C E++SRL
Sbjct: 194 KTAPRDTGAFDAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRL 253
Query: 237 CMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPH 296
C +RPC+ D+ IK GKKC+ + + F L+GC S ++Y+ K+CGVC D RCC P+
Sbjct: 254 CNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPY 313
Query: 297 RTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESL 339
++ T+ V F+CPDG + +++I C C+ +C NDIF L
Sbjct: 314 KSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIFADL 356
>gi|38202241 WNT1 inducible signaling pathway protein 3 isoform 3
[Homo sapiens]
Length = 372
Score = 273 bits (699), Expect = 1e-73
Identities = 133/326 (40%), Positives = 189/326 (57%), Gaps = 25/326 (7%)
Query: 23 PAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFC 82
P Q C PC+CP + PRCP GVSLV DGCGCC++CAKQ GE+C E D CDPHKGL+C
Sbjct: 60 PQRKQFCHWPCKCPQQK-PRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYC 118
Query: 83 DFGSPANR-KIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDV 141
D+ R + GVC C F Y +G+ FQ + + C C+ GA+GC PL
Sbjct: 119 DYSVDRPRYETGVCAYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPLF---- 174
Query: 142 RLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQT------VVGPALAAYRLEDTFGPDPTMI 195
+P KL G C + DQ+ ++ +Y+ + P +
Sbjct: 175 -IP----------KLAGSHCSGAKGGKKSDQSNCSLEPLLQQLSTSYKTMPAYRNLPLIW 223
Query: 196 RANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIK--KG 253
+ CLVQ T+W+ CS+TCGMGIS RVTN+N++C + K+ RLC ++PC++++ + IK KG
Sbjct: 224 KKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKG 283
Query: 254 KKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVM 313
K C T ++SK KF SGC+S ++Y+ FCG+C D RCC P+++ + ++F CP+
Sbjct: 284 KTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSF 343
Query: 314 KKNMMFIKTCACHYNCPGDNDIFESL 339
K M++I +C C NC DIF L
Sbjct: 344 KWKMLWITSCVCQRNCREPGDIFSEL 369
>gi|4507925 WNT1 inducible signaling pathway protein 3 isoform 1
[Homo sapiens]
Length = 354
Score = 273 bits (699), Expect = 1e-73
Identities = 133/326 (40%), Positives = 189/326 (57%), Gaps = 25/326 (7%)
Query: 23 PAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFC 82
P Q C PC+CP + PRCP GVSLV DGCGCC++CAKQ GE+C E D CDPHKGL+C
Sbjct: 42 PQRKQFCHWPCKCPQQK-PRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYC 100
Query: 83 DFGSPANR-KIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDV 141
D+ R + GVC C F Y +G+ FQ + + C C+ GA+GC PL
Sbjct: 101 DYSVDRPRYETGVCAYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPLF---- 156
Query: 142 RLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQT------VVGPALAAYRLEDTFGPDPTMI 195
+P KL G C + DQ+ ++ +Y+ + P +
Sbjct: 157 -IP----------KLAGSHCSGAKGGKKSDQSNCSLEPLLQQLSTSYKTMPAYRNLPLIW 205
Query: 196 RANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIK--KG 253
+ CLVQ T+W+ CS+TCGMGIS RVTN+N++C + K+ RLC ++PC++++ + IK KG
Sbjct: 206 KKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKG 265
Query: 254 KKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVM 313
K C T ++SK KF SGC+S ++Y+ FCG+C D RCC P+++ + ++F CP+
Sbjct: 266 KTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSF 325
Query: 314 KKNMMFIKTCACHYNCPGDNDIFESL 339
K M++I +C C NC DIF L
Sbjct: 326 KWKMLWITSCVCQRNCREPGDIFSEL 351
>gi|4507923 WNT1 inducible signaling pathway protein 2 precursor
[Homo sapiens]
Length = 250
Score = 216 bits (550), Expect = 2e-56
Identities = 111/233 (47%), Positives = 137/233 (58%), Gaps = 15/233 (6%)
Query: 16 LLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCD 75
LL L S+ Q C PC CP P PRCP GV LVLDGCGCCRVCA++LGE C + CD
Sbjct: 14 LLCLLSKVRT-QLCPTPCTCP-WPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCD 71
Query: 76 PHKGLFCDFGSPANRKIGVCT-AKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCM 134
+GL C G+ + +C A+D + C G +YR GE+FQ C +C C DG C+
Sbjct: 72 ASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCV 131
Query: 135 PLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDE-----PKDQTVVGPALAAYRLEDTFG 189
PLCS DVRLPS DCP PRRV++ GKCC EWVC + + GP + L +
Sbjct: 132 PLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSG--LVSSLP 189
Query: 190 PDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPC 242
P C +T W CS TCG+G++TRV+N N CRLE Q RLC+ RPC
Sbjct: 190 PG-----VPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPC 237
>gi|18491000 WNT1 inducible signaling pathway protein 1 isoform 2
precursor [Homo sapiens]
Length = 280
Score = 165 bits (418), Expect = 5e-41
Identities = 83/226 (36%), Positives = 122/226 (53%), Gaps = 11/226 (4%)
Query: 120 CKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRV--KLPGKCCEEWVCDEPK----DQT 173
CK+ C C P C + V L + C + +L C E +CD + D +
Sbjct: 49 CKWPCECPPSP----PRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYS 104
Query: 174 VVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQ 233
P A G R NC+ T+ WS CS +CG+G+STR++N NA C E++
Sbjct: 105 GDRPRYAIGVCAHAVGEVEAWHR-NCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQE 163
Query: 234 SRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCC 293
SRLC +RPC+ D+ IK GKKC+ + + F L+GC S ++Y+ K+CGVC D RCC
Sbjct: 164 SRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCC 223
Query: 294 TPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESL 339
P+++ T+ V F+CPDG + +++I C C+ +C NDIF L
Sbjct: 224 IPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIFADL 269
Score = 97.8 bits (242), Expect = 1e-20
Identities = 50/97 (51%), Positives = 59/97 (60%), Gaps = 7/97 (7%)
Query: 2 TAASMGPVRVAFVV--LLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRV 59
TA S P + F L SRP Q C PC CP P PRCP GVSL+ DGC CC++
Sbjct: 23 TALSPAPTTMDFTPAPLEDTSSRP---QFCKWPCECPPSP-PRCPLGVSLITDGCECCKM 78
Query: 60 CAKQLGELCTERDPCDPHKGLFCDF-GSPANRKIGVC 95
CA+QLG+ CTE CDPH+GL+CD+ G IGVC
Sbjct: 79 CAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVC 115
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 55.5 bits (132), Expect = 7e-08
Identities = 64/195 (32%), Positives = 77/195 (39%), Gaps = 44/195 (22%)
Query: 20 CSRPAVGQNCSGPCRCPDEPAPRCPAGV---SLVLDGCGC------CRVCAKQLGELCTE 70
C+RP SGP +C PRCP + + +DG C+ C Q G +
Sbjct: 467 CARPQ-----SGPGQC----CPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQ 517
Query: 71 RDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESF---QSSCKYQCTCL 127
PC C P G C D + C FGG Y SG F C+ C CL
Sbjct: 518 PRPCPRAP---CAHPLP-----GTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRL-CRCL 568
Query: 128 DGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALAAYRLEDT 187
G V C L V LP CP P V LPG+CC + C P P A R ++
Sbjct: 569 SGNVQC--LARRCVPLP---CPEP--VLLPGECCPQ--CPAPAG--CPRPGAAHARHQEY 617
Query: 188 FGP--DPTMIRANCL 200
F P DP R CL
Sbjct: 618 FSPPGDPCR-RCLCL 631
Score = 53.5 bits (127), Expect = 3e-07
Identities = 68/242 (28%), Positives = 87/242 (35%), Gaps = 50/242 (20%)
Query: 20 CSRPAVGQ-NCSGPCRCPDEPAPRCPA--------GVSLVLDGCGCCRVCAKQLGELCTE 70
C P+ + NC C P E P C G G CR+C G +
Sbjct: 168 CQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPG-DPCRICRCLEGHIQCR 226
Query: 71 RDPCDPHKGLFCDFGSPANRKIGVCTAK-DGAPCIFGGTVYRSGESFQSS--CKYQCTCL 127
+ C C + PA G C DG C G +RSGE S C + C C
Sbjct: 227 QREC----ASLCPY--PARPLPGTCCPVCDG--CFLNGREHRSGEPVGSGDPCSH-CRCA 277
Query: 128 DGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALAAYRLEDT 187
+G+V C PL P P P K+PG+CC VCD + Q Y+ ++T
Sbjct: 278 NGSVQCEPL-------PCPPVPCRHPGKIPGQCCP--VCDGCEYQG------HQYQSQET 322
Query: 188 FGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSR-LCMVRPCEADL 246
F + C Q E S + C + C L R LC CE D
Sbjct: 323 FRLQERGLCVRCSCQAGEVSCEEQECPV----------TPCALPASGRQLCPA--CELDG 370
Query: 247 EE 248
EE
Sbjct: 371 EE 372
Score = 52.4 bits (124), Expect = 6e-07
Identities = 48/163 (29%), Positives = 64/163 (39%), Gaps = 37/163 (22%)
Query: 21 SRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGC-------------CRVCAKQLGEL 67
+R V C P P E P+CPA G CR C G +
Sbjct: 576 ARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSV 635
Query: 68 CTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQS--SCKYQCT 125
+R PC P P R+ C + DG C++ G + SGE F S + + C
Sbjct: 636 SCQRLPCPP-----APCAHP--RQGPCCPSCDG--CLYQGKEFASGERFPSPTAACHLCL 686
Query: 126 CLDGAVGCMP-LCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCD 167
C +G+V C P C+ + CPFP R G CC + CD
Sbjct: 687 CWEGSVSCEPKACAPAL------CPFPAR----GDCCPD--CD 717
Score = 46.2 bits (108), Expect = 4e-05
Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 19/108 (17%)
Query: 57 CRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESF 116
C +C Q G + ++ PC P C SP VC + C+ G ++ GE F
Sbjct: 799 CSLCTCQEGSMRCQKKPCPP---ALCPHPSPGPCFCPVCHS-----CLSQGREHQDGEEF 850
Query: 117 QS---SCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCC 161
+ SC++ C C G V C VRL P P +V G CC
Sbjct: 851 EGPAGSCEW-CRCQAGQVSC-------VRLQCPPLPCKLQVTERGSCC 890
Score = 34.7 bits (78), Expect = 0.13
Identities = 44/163 (26%), Positives = 57/163 (34%), Gaps = 40/163 (24%)
Query: 31 GPCRCPDEPAPRCPAGVSL----VLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGS 86
G C P PR P L + C C K+ P DP + C G+
Sbjct: 512 GHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGN 571
Query: 87 P---ANRKI-----------GVCTAKDGAP--CIFGGTVYRSGESFQSS----CKYQCTC 126
A R + G C + AP C G + + + S C+ +C C
Sbjct: 572 VQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCR-RCLC 630
Query: 127 LDGAVGCMPLCSMDVRLPSP--DCPFPRRVKLPGKCCEEWVCD 167
LDG+V C RLP P C PR+ G CC CD
Sbjct: 631 LDGSVSCQ-------RLPCPPAPCAHPRQ----GPCCPS--CD 660
Score = 34.3 bits (77), Expect = 0.17
Identities = 26/81 (32%), Positives = 30/81 (37%), Gaps = 22/81 (27%)
Query: 95 CTAKDGAP-------------CIFGGTVYRSGESFQSSCKYQCTCLDGAVGCM-PLCSMD 140
C +DGA C G Y +GE+F C CL GAV C P CS
Sbjct: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSEL 176
Query: 141 VRLPSPDCPFPRRVKLPGKCC 161
L S PG+CC
Sbjct: 177 NCLES--------CTPPGECC 189
Score = 32.0 bits (71), Expect = 0.85
Identities = 42/161 (26%), Positives = 53/161 (32%), Gaps = 34/161 (21%)
Query: 34 RCPDEPAPR---CPAGVSLVLDGCGCCRVCAKQL-----GELCTERDPCDPHKGLFC--- 82
RC P CP L CC CA+ L G L +E P DP C
Sbjct: 990 RCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDL 1049
Query: 83 ----------DFGSPANRKI---GVCTAKDGAP---CIFGGTVYRSGESFQSSCKYQCTC 126
+ P + + G C AP C+ G SGE + C+C
Sbjct: 1050 TWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSC 1109
Query: 127 LDGAVGCM-----PLCSMDVRLP--SPDCPFPRRVKLPGKC 160
+ G V C PL + P SP PR + P C
Sbjct: 1110 MAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASC 1150
Score = 30.4 bits (67), Expect = 2.5
Identities = 39/143 (27%), Positives = 50/143 (34%), Gaps = 43/143 (30%)
Query: 32 PCRCPDEPAPRCPAGVSLVLDGC-----------------GCCRVCAKQLGELCTERDPC 74
PC P + P CP+ DGC C +C G + E C
Sbjct: 646 PCAHPRQ-GPCCPS-----CDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKAC 699
Query: 75 DPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESF---QSSCKYQCTCLDGAV 131
P C F + + C DG C + G Y S + F + C CTCL G V
Sbjct: 700 AP---ALCPFPARGD----CCPDCDG--CEYLGESYLSNQEFPDPREPCNL-CTCLGGFV 749
Query: 132 GC------MPLCSMDVRLPSPDC 148
C P CS + +PS C
Sbjct: 750 TCGRRPCEPPGCSHPL-IPSGHC 771
Score = 30.0 bits (66), Expect = 3.2
Identities = 38/146 (26%), Positives = 51/146 (34%), Gaps = 29/146 (19%)
Query: 18 ALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDG------CGCCRVCAKQLGELCTER 71
ALC P+ GPC CP C + DG G C C Q G++ R
Sbjct: 819 ALCPHPS-----PGPCFCP--VCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVR 871
Query: 72 DPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESF---QSSCKYQCTCLD 128
C P L C + C G C+ G + G + S+C C C +
Sbjct: 872 LQCPP---LPCKL--QVTERGSCCPRCRG--CLAHGEEHPEGSRWVPPDSACS-SCVCHE 923
Query: 129 GAVGCMPL-----CSMDVRLPSPDCP 149
G V C + C+ + P CP
Sbjct: 924 GVVTCARIQCISSCAQPRQGPHDCCP 949
>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
Length = 814
Score = 55.1 bits (131), Expect = 9e-08
Identities = 63/195 (32%), Positives = 76/195 (38%), Gaps = 41/195 (21%)
Query: 20 CSRPAVGQNCSGPCRCPDEPAPRCPAGV---SLVLDGCGC------CRVCAKQLGELCTE 70
C+RP SGP +C PRCP + + +DG C+ C Q G +
Sbjct: 525 CARPQ-----SGPGQC----CPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQ 575
Query: 71 RDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESF---QSSCKYQCTCL 127
PC C P G C D + C FGG Y SG F C+ C CL
Sbjct: 576 PRPCPRAP---CAHPLP-----GTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRL-CRCL 626
Query: 128 DGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALAAYRLEDT 187
G V C L V LP CP P V LPG+CC + P P A R ++
Sbjct: 627 SGNVQC--LARRCVPLP---CPEP--VLLPGECCPQCPA-APAPAGCPRPGAAHARHQEY 678
Query: 188 FGP--DPTMIRANCL 200
F P DP R CL
Sbjct: 679 FSPPGDPCR-RCLCL 692
Score = 50.8 bits (120), Expect = 2e-06
Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 34/163 (20%)
Query: 21 SRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGL 80
+R V C P P E P+CPA + GC R A P DP +
Sbjct: 634 ARRCVPLPCPEPVLLPGECCPQCPAAPA----PAGCPRPGAAHARHQEYFSPPGDPCRRC 689
Query: 81 FCDFGSPANRKIGV-------------CTAKDGAPCIFGGTVYRSGESFQS--SCKYQCT 125
C GS + +++ C + DG C++ G + SGE F S + + C
Sbjct: 690 LCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDG--CLYQGKEFASGERFPSPTAACHLCL 747
Query: 126 CLDGAVGCMP-LCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCD 167
C +G+V C P C+ + CPFP R G CC + CD
Sbjct: 748 CWEGSVSCEPKACAPAL------CPFPAR----GDCCPD--CD 778
Score = 50.4 bits (119), Expect = 2e-06
Identities = 57/196 (29%), Positives = 74/196 (37%), Gaps = 40/196 (20%)
Query: 57 CRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAK-DGAPCIFGGTVYRSGES 115
CR+C G + + C C + PA G C DG C G +RSGE
Sbjct: 271 CRICRCLEGHIQCRQREC----ASLCPY--PARPLPGTCCPVCDG--CFLNGREHRSGEP 322
Query: 116 FQSS--CKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQT 173
S C + C C +G+V C PL P P P K+PG+CC VCD + Q
Sbjct: 323 VGSGDPCSH-CRCANGSVQCEPL-------PCPPVPCRHPGKIPGQCCP--VCDGCEYQG 372
Query: 174 VVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQ 233
Y+ ++TF + C Q E S + C + C L
Sbjct: 373 ------HQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPV----------TPCALPAS 416
Query: 234 SR-LCMVRPCEADLEE 248
R LC CE D EE
Sbjct: 417 GRQLCPA--CELDGEE 430
Score = 45.4 bits (106), Expect = 7e-05
Identities = 37/116 (31%), Positives = 44/116 (37%), Gaps = 30/116 (25%)
Query: 52 DGCGCCRVCAKQLGELCTERDPCD----PHKGLFCDFGSPANRKIGVCTAKDGAPCIFGG 107
D C CR C + G + + PC P G C P C + G
Sbjct: 154 DACTTCR-CLE--GTITCNQKPCPRGPCPEPGACCPHCKPG--------------CDYEG 196
Query: 108 TVYRSGESFQSSCK--YQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCC 161
+Y G +F SS QCTCL V CM L + P CP P V PG CC
Sbjct: 197 QLYEEGVTFLSSSNPCLQCTCLRSRVRCMAL-----KCPPSPCPEP--VLRPGHCC 245
Score = 36.6 bits (83), Expect = 0.034
Identities = 49/200 (24%), Positives = 61/200 (30%), Gaps = 83/200 (41%)
Query: 32 PCRCPDE-PAPRCPAGVSLVLDGC------------------GCCRVCAKQLGELCTERD 72
PCR P + P CP V DGC G C C+ Q GE+ E
Sbjct: 350 PCRHPGKIPGQCCP-----VCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQ 404
Query: 73 PCD------PHKGL----FCDFG----------SPANRKIGVCTAKDGAP---------- 102
C P G C+ P R C +DG P
Sbjct: 405 ECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPA 464
Query: 103 ------------------CIFGGTVYRSGESF---QSSCKYQCTCLDGAVGCMPLCSMDV 141
C + VY +G++F S C + C C DG V C V
Sbjct: 465 PCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPC-HACHCQDGTVTCSL-----V 518
Query: 142 RLPSPDCPFPRRVKLPGKCC 161
P C P+ PG+CC
Sbjct: 519 DCPPTTCARPQ--SGPGQCC 536
Score = 35.4 bits (80), Expect = 0.077
Identities = 23/80 (28%), Positives = 29/80 (36%), Gaps = 24/80 (30%)
Query: 95 CTAKDGAP-------------CIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDV 141
C +DGA C G Y +GE+F C CL+G + C
Sbjct: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCN------- 169
Query: 142 RLPSPDCPFPRRVKLPGKCC 161
+ P P P P PG CC
Sbjct: 170 QKPCPRGPCPE----PGACC 185
Score = 32.0 bits (71), Expect = 0.85
Identities = 44/166 (26%), Positives = 56/166 (33%), Gaps = 43/166 (25%)
Query: 31 GPCRCPDEPAPRCPAGVSL----VLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGS 86
G C P PR P L + C C K+ P DP + C G+
Sbjct: 570 GHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGN 629
Query: 87 P---ANRKI-----------GVC-----TAKDGAPCIFGGTVYRSGESFQSS----CKYQ 123
A R + G C A A C G + + + S C+ +
Sbjct: 630 VQCLARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCR-R 688
Query: 124 CTCLDGAVGCMPLCSMDVRLPSP--DCPFPRRVKLPGKCCEEWVCD 167
C CLDG+V C RLP P C PR+ G CC CD
Sbjct: 689 CLCLDGSVSCQ-------RLPCPPAPCAHPRQ----GPCCPS--CD 721
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 54.3 bits (129), Expect = 2e-07
Identities = 45/147 (30%), Positives = 65/147 (44%), Gaps = 26/147 (17%)
Query: 26 GQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCD---PHKGLFC 82
G +CSG C P E + V + + C VC+ + G++ R CD P LFC
Sbjct: 580 GPSCSGDC--PHEGGLKHNGQVWTLKEDR--CSVCSCKDGKIFCRRTACDCQNPSADLFC 635
Query: 83 DFGSPANRKIGVCTAKDGAPCIF--GGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMD 140
C + + C+ G +YRSG+++ SC+ QC CL+G V C PL
Sbjct: 636 ---------CPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQ-QCRCLEGEVDCWPL---- 681
Query: 141 VRLPSPDCPFPRRVKLPGKCCEEWVCD 167
P+ C + L G+CC V D
Sbjct: 682 -TCPNLSCEY--TAILEGECCPRCVSD 705
Score = 31.2 bits (69), Expect = 1.4
Identities = 61/264 (23%), Positives = 89/264 (33%), Gaps = 56/264 (21%)
Query: 57 CRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESF 116
CR C + G + R C P L C S G C CI+GG V G+
Sbjct: 292 CRNCTCKSGAVECRRMSCPP---LNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRI 348
Query: 117 QS-SCKYQCTCLDGAVG-----CMPL-CS-MDVRLPSPDCPFPRRVKLPGKCCEEWVCDE 168
+ SC+ C G + C PL CS D LP C R + C E C E
Sbjct: 349 LTKSCR---ECRGGVLVKITEMCPPLNCSEKDHILPENQCC--RVCRGHNFCAEGPKCGE 403
Query: 169 PKDQ----------------TVVGPALAAYRLEDTFGPD------------PTMIRANCL 200
+ +V G + +++ P + R +C+
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCV 463
Query: 201 ---VQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRP--------CEADLEEN 249
++ ++S C++ G ++NA C Q C +P C A EE
Sbjct: 464 PGYIRVDDFS-CTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEG 522
Query: 250 IKKGKKCIRTPKISKPIKFELSGC 273
+ G C+ K P F S C
Sbjct: 523 CRYGGTCVAPNKCVCPSGFTGSHC 546
Score = 30.0 bits (66), Expect = 3.2
Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 7/62 (11%)
Query: 103 CIFGGTVYRSGESFQSS--CKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKC 160
C G +YR +S+ C+ CTC GAV C + + P V + G+C
Sbjct: 273 CQVSGLLYRDQDSWVDGDHCR-NCTCKSGAVECRRMSCPPLNCSPDSLP----VHIAGQC 327
Query: 161 CE 162
C+
Sbjct: 328 CK 329
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 54.3 bits (129), Expect = 2e-07
Identities = 45/147 (30%), Positives = 65/147 (44%), Gaps = 26/147 (17%)
Query: 26 GQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCD---PHKGLFC 82
G +CSG C P E + V + + C VC+ + G++ R CD P LFC
Sbjct: 627 GPSCSGDC--PHEGGLKHNGQVWTLKEDR--CSVCSCKDGKIFCRRTACDCQNPSADLFC 682
Query: 83 DFGSPANRKIGVCTAKDGAPCIF--GGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMD 140
C + + C+ G +YRSG+++ SC+ QC CL+G V C PL
Sbjct: 683 ---------CPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQ-QCRCLEGEVDCWPL---- 728
Query: 141 VRLPSPDCPFPRRVKLPGKCCEEWVCD 167
P+ C + L G+CC V D
Sbjct: 729 -TCPNLSCEY--TAILEGECCPRCVSD 752
Score = 33.9 bits (76), Expect = 0.22
Identities = 69/300 (23%), Positives = 100/300 (33%), Gaps = 65/300 (21%)
Query: 57 CRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESF 116
CR C + G + R C P L C S G C CI+GG V G+
Sbjct: 292 CRNCTCKSGAVECRRMSCPP---LNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRI 348
Query: 117 QS-SCKYQCTCLDGAVG-----CMPL-CS-MDVRLPSPDCPFPRRVKLPGKCCEEWVCDE 168
+ SC+ C G + C PL CS D LP C R + C E C E
Sbjct: 349 LTKSCR---ECRGGVLVKITEMCPPLNCSEKDHILPENQCC--RVCRGHNFCAEGPKCGE 403
Query: 169 PKDQ----------------TVVGPALAAYRLEDTFGPD------------PTMIRANCL 200
+ +V G + +++ P + R +C+
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCV 463
Query: 201 ---VQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRP--------CEADLEEN 249
++ ++S C++ G ++NA C Q C +P C A EE
Sbjct: 464 PGYIRVDDFS-CTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEG 522
Query: 250 IKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDG--RCCTPHRTTTLPVEFKC 307
+ G C+ K P F S C K C++G C R LP + C
Sbjct: 523 CRYGGTCVAPNKCVCPSGFTGSHC-------EKDIDECSEGIIECHNHSRCVNLPGWYHC 575
Score = 30.0 bits (66), Expect = 3.2
Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 7/62 (11%)
Query: 103 CIFGGTVYRSGESFQSS--CKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKC 160
C G +YR +S+ C+ CTC GAV C + + P V + G+C
Sbjct: 273 CQVSGLLYRDQDSWVDGDHCR-NCTCKSGAVECRRMSCPPLNCSPDSLP----VHIAGQC 327
Query: 161 CE 162
C+
Sbjct: 328 CK 329
>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
Length = 839
Score = 52.8 bits (125), Expect = 5e-07
Identities = 45/154 (29%), Positives = 64/154 (41%), Gaps = 26/154 (16%)
Query: 26 GQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCD---PHKGLFC 82
G+NC+G C + G VL+ C VC+ Q G + R CD P LFC
Sbjct: 656 GKNCTGDCIHDGKVKHN---GQIWVLEN-DRCSVCSCQNGFVMCRRMVCDCENPTVDLFC 711
Query: 83 DFGSPANRKIGVCTAKDGAPCIF--GGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMD 140
C + + C+ G T+Y SG+++ +C+ QC CL G V C P
Sbjct: 712 ---------CPECDPRLSSQCLHQNGETLYNSGDTWVQNCQ-QCRCLQGEVDCWP----- 756
Query: 141 VRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTV 174
LP PD + +CC V D + T+
Sbjct: 757 --LPCPDVECEFSILPENECCPRCVTDPCQADTI 788
Score = 50.4 bits (119), Expect = 2e-06
Identities = 26/62 (41%), Positives = 33/62 (53%), Gaps = 7/62 (11%)
Query: 103 CIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVK-LPGKCC 161
C GT YR ES+ CK CTCL+G + C L P+PDCP + + GKCC
Sbjct: 297 CTMKGTTYREFESWIDGCK-NCTCLNGTIQCETLI-----CPNPDCPLKSALAYVDGKCC 350
Query: 162 EE 163
+E
Sbjct: 351 KE 352
Score = 28.5 bits (62), Expect = 9.4
Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 20/80 (25%)
Query: 93 GVCTAKDGAPCIFGGTVYRSGES---FQSS-------CKYQCTCLDGAVGCMPLCSMDVR 142
G C + + C F G Y GE + SS CK Q L + GC
Sbjct: 347 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGC--------- 397
Query: 143 LPSPDCPFPRRVKLPGKCCE 162
P+ DCP ++ L CC+
Sbjct: 398 -PALDCPESHQITLSHSCCK 416
>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
Length = 815
Score = 52.8 bits (125), Expect = 5e-07
Identities = 45/154 (29%), Positives = 64/154 (41%), Gaps = 26/154 (16%)
Query: 26 GQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCD---PHKGLFC 82
G+NC+G C + G VL+ C VC+ Q G + R CD P LFC
Sbjct: 632 GKNCTGDCIHDGKVKHN---GQIWVLEN-DRCSVCSCQNGFVMCRRMVCDCENPTVDLFC 687
Query: 83 DFGSPANRKIGVCTAKDGAPCIF--GGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMD 140
C + + C+ G T+Y SG+++ +C+ QC CL G V C P
Sbjct: 688 ---------CPECDPRLSSQCLHQNGETLYNSGDTWVQNCQ-QCRCLQGEVDCWP----- 732
Query: 141 VRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTV 174
LP PD + +CC V D + T+
Sbjct: 733 --LPCPDVECEFSILPENECCPRCVTDPCQADTI 764
Score = 50.4 bits (119), Expect = 2e-06
Identities = 26/62 (41%), Positives = 33/62 (53%), Gaps = 7/62 (11%)
Query: 103 CIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVK-LPGKCC 161
C GT YR ES+ CK CTCL+G + C L P+PDCP + + GKCC
Sbjct: 273 CTMKGTTYREFESWIDGCK-NCTCLNGTIQCETLI-----CPNPDCPLKSALAYVDGKCC 326
Query: 162 EE 163
+E
Sbjct: 327 KE 328
Score = 28.5 bits (62), Expect = 9.4
Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 20/80 (25%)
Query: 93 GVCTAKDGAPCIFGGTVYRSGES---FQSS-------CKYQCTCLDGAVGCMPLCSMDVR 142
G C + + C F G Y GE + SS CK Q L + GC
Sbjct: 323 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGC--------- 373
Query: 143 LPSPDCPFPRRVKLPGKCCE 162
P+ DCP ++ L CC+
Sbjct: 374 -PALDCPESHQITLSHSCCK 392
>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 52.8 bits (125), Expect = 5e-07
Identities = 45/154 (29%), Positives = 64/154 (41%), Gaps = 26/154 (16%)
Query: 26 GQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCD---PHKGLFC 82
G+NC+G C + G VL+ C VC+ Q G + R CD P LFC
Sbjct: 633 GKNCTGDCIHDGKVKHN---GQIWVLEN-DRCSVCSCQNGFVMCRRMVCDCENPTVDLFC 688
Query: 83 DFGSPANRKIGVCTAKDGAPCIF--GGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMD 140
C + + C+ G T+Y SG+++ +C+ QC CL G V C P
Sbjct: 689 ---------CPECDPRLSSQCLHQNGETLYNSGDTWVQNCQ-QCRCLQGEVDCWP----- 733
Query: 141 VRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTV 174
LP PD + +CC V D + T+
Sbjct: 734 --LPCPDVECEFSILPENECCPRCVTDPCQADTI 765
Score = 50.4 bits (119), Expect = 2e-06
Identities = 26/62 (41%), Positives = 33/62 (53%), Gaps = 7/62 (11%)
Query: 103 CIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVK-LPGKCC 161
C GT YR ES+ CK CTCL+G + C L P+PDCP + + GKCC
Sbjct: 274 CTMKGTTYREFESWIDGCK-NCTCLNGTIQCETLI-----CPNPDCPLKSALAYVDGKCC 327
Query: 162 EE 163
+E
Sbjct: 328 KE 329
Score = 28.5 bits (62), Expect = 9.4
Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 20/80 (25%)
Query: 93 GVCTAKDGAPCIFGGTVYRSGES---FQSS-------CKYQCTCLDGAVGCMPLCSMDVR 142
G C + + C F G Y GE + SS CK Q L + GC
Sbjct: 324 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGC--------- 374
Query: 143 LPSPDCPFPRRVKLPGKCCE 162
P+ DCP ++ L CC+
Sbjct: 375 -PALDCPESHQITLSHSCCK 393
>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
Length = 866
Score = 52.8 bits (125), Expect = 5e-07
Identities = 45/154 (29%), Positives = 64/154 (41%), Gaps = 26/154 (16%)
Query: 26 GQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCD---PHKGLFC 82
G+NC+G C + G VL+ C VC+ Q G + R CD P LFC
Sbjct: 683 GKNCTGDCIHDGKVKHN---GQIWVLEN-DRCSVCSCQNGFVMCRRMVCDCENPTVDLFC 738
Query: 83 DFGSPANRKIGVCTAKDGAPCIF--GGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMD 140
C + + C+ G T+Y SG+++ +C+ QC CL G V C P
Sbjct: 739 ---------CPECDPRLSSQCLHQNGETLYNSGDTWVQNCQ-QCRCLQGEVDCWP----- 783
Query: 141 VRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTV 174
LP PD + +CC V D + T+
Sbjct: 784 --LPCPDVECEFSILPENECCPRCVTDPCQADTI 815
Score = 50.4 bits (119), Expect = 2e-06
Identities = 26/62 (41%), Positives = 33/62 (53%), Gaps = 7/62 (11%)
Query: 103 CIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVK-LPGKCC 161
C GT YR ES+ CK CTCL+G + C L P+PDCP + + GKCC
Sbjct: 324 CTMKGTTYREFESWIDGCK-NCTCLNGTIQCETLI-----CPNPDCPLKSALAYVDGKCC 377
Query: 162 EE 163
+E
Sbjct: 378 KE 379
Score = 28.5 bits (62), Expect = 9.4
Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 20/80 (25%)
Query: 93 GVCTAKDGAPCIFGGTVYRSGES---FQSS-------CKYQCTCLDGAVGCMPLCSMDVR 142
G C + + C F G Y GE + SS CK Q L + GC
Sbjct: 374 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGC--------- 424
Query: 143 LPSPDCPFPRRVKLPGKCCE 162
P+ DCP ++ L CC+
Sbjct: 425 -PALDCPESHQITLSHSCCK 443
>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 52.8 bits (125), Expect = 5e-07
Identities = 45/154 (29%), Positives = 64/154 (41%), Gaps = 26/154 (16%)
Query: 26 GQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCD---PHKGLFC 82
G+NC+G C + G VL+ C VC+ Q G + R CD P LFC
Sbjct: 633 GKNCTGDCIHDGKVKHN---GQIWVLEN-DRCSVCSCQNGFVMCRRMVCDCENPTVDLFC 688
Query: 83 DFGSPANRKIGVCTAKDGAPCIF--GGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMD 140
C + + C+ G T+Y SG+++ +C+ QC CL G V C P
Sbjct: 689 ---------CPECDPRLSSQCLHQNGETLYNSGDTWVQNCQ-QCRCLQGEVDCWP----- 733
Query: 141 VRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTV 174
LP PD + +CC V D + T+
Sbjct: 734 --LPCPDVECEFSILPENECCPRCVTDPCQADTI 765
Score = 50.4 bits (119), Expect = 2e-06
Identities = 26/62 (41%), Positives = 33/62 (53%), Gaps = 7/62 (11%)
Query: 103 CIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVK-LPGKCC 161
C GT YR ES+ CK CTCL+G + C L P+PDCP + + GKCC
Sbjct: 274 CTMKGTTYREFESWIDGCK-NCTCLNGTIQCETLI-----CPNPDCPLKSALAYVDGKCC 327
Query: 162 EE 163
+E
Sbjct: 328 KE 329
Score = 28.5 bits (62), Expect = 9.4
Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 20/80 (25%)
Query: 93 GVCTAKDGAPCIFGGTVYRSGES---FQSS-------CKYQCTCLDGAVGCMPLCSMDVR 142
G C + + C F G Y GE + SS CK Q L + GC
Sbjct: 324 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGC--------- 374
Query: 143 LPSPDCPFPRRVKLPGKCCE 162
P+ DCP ++ L CC+
Sbjct: 375 -PALDCPESHQITLSHSCCK 393
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 50.8 bits (120), Expect = 2e-06
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 13/107 (12%)
Query: 27 QNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGS 86
QNCSG D P+ + R C+ + + E PC +G FC G
Sbjct: 1215 QNCSGGAEYVDCSDPKAQRRTN---------RTCSTRNIPVFDENLPCK--RGCFCPEGM 1263
Query: 87 PANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGC 133
N K G+C + PC FGG Y G C +CTC+ G+ C
Sbjct: 1264 VRNSK-GICVFPNDCPCSFGGREYDEGSVTSVGCN-ECTCIKGSWSC 1308
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/98 (33%), Positives = 36/98 (36%), Gaps = 15/98 (15%)
Query: 42 RCPAGVSLVLDGCG------CCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVC 95
RCP + CG C V Q E C C P L D G G C
Sbjct: 761 RCPE--QHIYKECGPSNPATCSNVAPFQDSE-CVSGCTC-PEGYLLDDIGEK-----GKC 811
Query: 96 TAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGC 133
K PC GTVY+ GE + C QCTC D C
Sbjct: 812 VLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSC 849
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 50.8 bits (120), Expect = 2e-06
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 13/107 (12%)
Query: 27 QNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGS 86
QNCSG D P+ + R C+ + + E PC +G FC G
Sbjct: 1215 QNCSGGAEYVDCSDPKAQRRTN---------RTCSTRNIPVFDENLPCK--RGCFCPEGM 1263
Query: 87 PANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGC 133
N K G+C + PC FGG Y G C +CTC+ G+ C
Sbjct: 1264 VRNSK-GICVFPNDCPCSFGGREYDEGSVTSVGCN-ECTCIKGSWSC 1308
Score = 42.4 bits (98), Expect = 6e-04
Identities = 36/108 (33%), Positives = 39/108 (36%), Gaps = 21/108 (19%)
Query: 31 GPCRCPD-----EPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFG 85
G RCP+ E P PA C V Q E C C P L D G
Sbjct: 758 GTQRCPEQHIYKECGPSNPAT---------CSNVAPFQDSE-CVSGCTC-PEGYLLDDIG 806
Query: 86 SPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGC 133
G C K PC GTVY+ GE + C QCTC D C
Sbjct: 807 EK-----GKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSC 849
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 47.0 bits (110), Expect = 3e-05
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 26/118 (22%)
Query: 57 CRVCAKQLGELCTERDPCDP----HKGL-FCDFGSPANRKIGVCTAKDGAPCIFGGTVYR 111
C VC+ GE+ PC P H+ L F GS +G+ G PC + G V++
Sbjct: 113 CSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGL-----GKPCSYEGHVFQ 167
Query: 112 SGESFQSSCKYQCTCLDG-----AVGCMPL-CSMDVRLPSPDCPFPRRVKLPGKCCEE 163
GE ++ S +C C +G C PL C+ D + V++PGKCC +
Sbjct: 168 DGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQDETV----------VRVPGKCCPQ 215
Score = 41.6 bits (96), Expect = 0.001
Identities = 45/179 (25%), Positives = 62/179 (34%), Gaps = 43/179 (24%)
Query: 21 SRPAVGQNCS-GPCRCPDEPAPRCPAG---VSLVLDGCGCCRVCAKQLGELCTERD---- 72
S P +C+ G RC +P P G ++ + +G CC VC LG+ C+
Sbjct: 110 SSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEG-SCCPVCVG-LGKPCSYEGHVFQ 167
Query: 73 -------------------------PCDPHKGLFCDFGSPANRKIGVCTAKDGA-PCIFG 106
C P LFC+ R G C + A C
Sbjct: 168 DGEDWRLSRCAKCLCRNGVAQCFTAQCQP---LFCNQDETVVRVPGKCCPQCSARSCSAA 224
Query: 107 GTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWV 165
G VY GE + + C C G V C + +R R + G+CCEE V
Sbjct: 225 GQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQ----SRARRHGQCCEECV 279
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/159 (25%), Positives = 55/159 (34%), Gaps = 27/159 (16%)
Query: 20 CSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGC----GCCRVCAKQLGELCTERDPCD 75
C++ G C CP A C A + G C C GE+ + C
Sbjct: 199 CNQDETVVRVPGKC-CPQCSARSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACL 257
Query: 76 PHKGLFCDFGSPANRKIGVCTAKDGAP---CIFGGTVYRSGESFQSSCKYQCTCLDGAVG 132
P L C G R+ G C + +P C + G V E ++ S C C G V
Sbjct: 258 P---LRCGKGQSRARRHGQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVT 314
Query: 133 CMP------LCSMDVRLPSPDCPFPRRVKLPGKCCEEWV 165
C C+ D L + L GKCC E +
Sbjct: 315 CQTGECAKVECARDEEL----------IHLDGKCCPECI 343
>gi|5901946 endothelial cell-specific molecule 1 isoform a precursor
[Homo sapiens]
Length = 184
Score = 45.4 bits (106), Expect = 7e-05
Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 24/107 (22%)
Query: 32 PCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELC------TERDPCDPHKGLFCDFG 85
P C P VLD CGCCRVCA GE C + C P GL C
Sbjct: 29 PQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGP--GLRCQPS 86
Query: 86 S---PANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDG 129
+ P + G+C KD C +G +F C+ C C G
Sbjct: 87 NGEDPFGEEFGIC--KD---CPYG--------TFGMDCRETCNCQSG 120
>gi|40353769 chordin-like 2 [Homo sapiens]
Length = 451
Score = 44.3 bits (103), Expect = 2e-04
Identities = 52/212 (24%), Positives = 73/212 (34%), Gaps = 61/212 (28%)
Query: 2 TAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCA 61
+A + P R+ +L C+ GQ G CP+ P CPA + L CC+ C
Sbjct: 125 SAHELFPSRLPNQCVLCSCTE---GQIYCGLTTCPE---PGCPAPLPL---PDSCCQACK 175
Query: 62 KQLGELCTE-------------RDPCDPHKGLFCDFGSPANRKIG--------------- 93
+ E E +DPC G G+PA +
Sbjct: 176 DEASEQSDEEDSVQSLHGVRHPQDPCSSDAGRKRGPGTPAPTGLSAPLSFIPRHFRPKGA 235
Query: 94 -------VCTAKDGAPCIFGGTVYRSGESFQSSCK-------YQCTCLDGAVGCMPLCSM 139
V K C+ GG Y GE + + + CTC DG C
Sbjct: 236 GSTTVKIVLKEKHKKACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQ----- 290
Query: 140 DVRLPSP-DCPFPRRVKLPGKCCEEWVCDEPK 170
R+ P + P K+ GKCC+ +C E K
Sbjct: 291 --RVTCPTEYPCRHPEKVAGKCCK--ICPEDK 318
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 43.9 bits (102), Expect = 2e-04
Identities = 33/108 (30%), Positives = 40/108 (37%), Gaps = 10/108 (9%)
Query: 34 RCPDEPAPRCPAGVSLVLDGCGCCRVCAK-QLGELCTERDPCDPHKGLFCDFGSPANRKI 92
RCP+ CP + G C C+ Q +LC D C G FC G
Sbjct: 976 RCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLC--EDHCVD--GCFCPPGRSCTVLD 1031
Query: 93 GV----CTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPL 136
+ C PC GG Y G SF ++C CTC G C L
Sbjct: 1032 DITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCS-SCTCSGGLWQCQDL 1078
Score = 35.8 bits (81), Expect = 0.059
Identities = 50/223 (22%), Positives = 74/223 (33%), Gaps = 32/223 (14%)
Query: 103 CIFGGTVYRSGESFQSSCK-YQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVK-LPGKC 160
C + GT Y G +F + + CTCL G + + + CP K + G+C
Sbjct: 5860 CSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQC 5919
Query: 161 CEEWV---CDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGI 217
C E V C P Q V +L +T+ N V C G+ +
Sbjct: 5920 CGECVQTACLTPDGQPV--------QLNETW--------VNSHVDNCTVYLCEAEGGVHL 5963
Query: 218 ST---RVTNDNASCRLEKQSRLCMVR----PCEADLEENIKKGKKCIRTPKISKPIKFEL 270
T D +SCR + C C+ + I + C + I F
Sbjct: 5964 LTPQPASCPDVSSCRGSLRKTGCCYSCEEDSCQVRINTTILWHQGC----ETEVNITFCE 6019
Query: 271 SGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVM 313
C Y A+ + CC R V CP+G +
Sbjct: 6020 GSCPGASKYSAEAQAMQHQCTCCQERRVHEETVPLHCPNGSAI 6062
Score = 32.7 bits (73), Expect = 0.50
Identities = 29/107 (27%), Positives = 38/107 (35%), Gaps = 21/107 (19%)
Query: 20 CSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKG 79
C+ P V +CS P C + GC C C P G
Sbjct: 1453 CAAPMVYLDCSNSSA--GTPGAECLRSCHTLDVGC---------FSTHCVSGCVCPP--G 1499
Query: 80 LFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTC 126
L D GS G C A++ PC+ Y+ GE+ + C CTC
Sbjct: 1500 LVSD-GS------GGCIAEEDCPCVHNEATYKPGETIRVDCN-TCTC 1538
Score = 29.6 bits (65), Expect = 4.2
Identities = 18/59 (30%), Positives = 22/59 (37%), Gaps = 2/59 (3%)
Query: 76 PHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCM 134
P G C G+ N G C PC GTV GE C+C G + C+
Sbjct: 1387 PVDGCTCPAGTFLN-DAGACVPAQECPCYAHGTVLAPGEVVHDEGAV-CSCTGGKLSCL 1443
Score = 28.9 bits (63), Expect = 7.2
Identities = 41/161 (25%), Positives = 61/161 (37%), Gaps = 30/161 (18%)
Query: 144 PSPDCPFPRRVKLPGKCC--EEWVCDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLV 201
P+ CP P + LP C EE +C +T++GPA A E D T A C
Sbjct: 896 PTEQCPDP--LPLPAGNCTDEEGICH----RTLLGPAFA----ECHALVDSTAYLAACAQ 945
Query: 202 QTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPK 261
C + S + + R + LC R C +++ + G C T
Sbjct: 946 DLCRCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCP-RTCPLNMQHQ-ECGSPCTDT-- 1001
Query: 262 ISKPIKFELSGCTSMKTYRAKFC-GVCTDGRCCTPHRTTTL 301
C++ + RA+ C C DG C P R+ T+
Sbjct: 1002 -----------CSNPQ--RAQLCEDHCVDGCFCPPGRSCTV 1029
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 43.9 bits (102), Expect = 2e-04
Identities = 33/108 (30%), Positives = 40/108 (37%), Gaps = 10/108 (9%)
Query: 34 RCPDEPAPRCPAGVSLVLDGCGCCRVCAK-QLGELCTERDPCDPHKGLFCDFGSPANRKI 92
RCP+ CP + G C C+ Q +LC D C G FC G
Sbjct: 320 RCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLC--EDHCVD--GCFCPPGRSCTVLD 375
Query: 93 GV----CTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPL 136
+ C PC GG Y G SF ++C CTC G C L
Sbjct: 376 DITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCS-SCTCSGGLWQCQDL 422
Score = 41.2 bits (95), Expect = 0.001
Identities = 53/239 (22%), Positives = 78/239 (32%), Gaps = 32/239 (13%)
Query: 103 CIFGGTVYRSGESFQSSCK-YQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVK-LPGKC 160
C + GT Y G +F + + CTCL G + + + CP K + G+C
Sbjct: 5526 CSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQC 5585
Query: 161 CEEWV---CDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGI 217
C E V C P Q V +L +T+ N V C G+ +
Sbjct: 5586 CGECVQTACLTPDGQPV--------QLNETW--------VNSHVDNCTVYLCEAEGGVHL 5629
Query: 218 ST---RVTNDNASCRLEKQSRLCMVR----PCEADLEENIKKGKKCIRTPKISKPIKFEL 270
T D +SCR + C C+ + I + C + I F
Sbjct: 5630 LTPQPASCPDVSSCRGSLRKTGCCYSCEEDSCQVRINTTILWHQGC----ETEVNITFCE 5685
Query: 271 SGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNC 329
C Y A+ + CC R V CP+G + + C C C
Sbjct: 5686 GSCPGASKYSAEAQAMQHQCTCCQERRVHEETVPLHCPNGSAILHTYTHVDECGCTPFC 5744
Score = 32.7 bits (73), Expect = 0.50
Identities = 29/107 (27%), Positives = 38/107 (35%), Gaps = 21/107 (19%)
Query: 20 CSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKG 79
C+ P V +CS P C + GC C C P G
Sbjct: 797 CAAPMVYLDCSNSSA--GTPGAECLRSCHTLDVGC---------FSTHCVSGCVCPP--G 843
Query: 80 LFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTC 126
L D GS G C A++ PC+ Y+ GE+ + C CTC
Sbjct: 844 LVSD-GS------GGCIAEEDCPCVHNEATYKPGETIRVDCN-TCTC 882
Score = 29.6 bits (65), Expect = 4.2
Identities = 18/59 (30%), Positives = 22/59 (37%), Gaps = 2/59 (3%)
Query: 76 PHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCM 134
P G C G+ N G C PC GTV GE C+C G + C+
Sbjct: 731 PVDGCTCPAGTFLN-DAGACVPAQECPCYAHGTVLAPGEVVHDEGAV-CSCTGGKLSCL 787
Score = 28.9 bits (63), Expect = 7.2
Identities = 41/161 (25%), Positives = 61/161 (37%), Gaps = 30/161 (18%)
Query: 144 PSPDCPFPRRVKLPGKCC--EEWVCDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLV 201
P+ CP P + LP C EE +C +T++GPA A E D T A C
Sbjct: 240 PTEQCPDP--LPLPAGNCTDEEGICH----RTLLGPAFA----ECHALVDSTAYLAACAQ 289
Query: 202 QTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPK 261
C + S + + R + LC R C +++ + G C T
Sbjct: 290 DLCRCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCP-RTCPLNMQHQ-ECGSPCTDT-- 345
Query: 262 ISKPIKFELSGCTSMKTYRAKFC-GVCTDGRCCTPHRTTTL 301
C++ + RA+ C C DG C P R+ T+
Sbjct: 346 -----------CSNPQ--RAQLCEDHCVDGCFCPPGRSCTV 373
>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
sapiens]
Length = 278
Score = 43.5 bits (101), Expect = 3e-04
Identities = 37/96 (38%), Positives = 39/96 (40%), Gaps = 14/96 (14%)
Query: 31 GPCRCPDEPAPR-CPAGVSLVLDGCGCCRVCAKQLGELCTER--DPCDPHKGLFC--DFG 85
GPCR PAP CPA LD CGCC C G C R C P GL C
Sbjct: 39 GPCRPEGCPAPAPCPAPGISALDECGCCARCLGAEGASCGGRAGGRCGP--GLVCASQAA 96
Query: 86 SPANRKIGVCTAKDGAPCIFGGTVYRS-GESFQSSC 120
A G+C C GTV S G S+ S C
Sbjct: 97 GAAPEGTGLCV------CAQRGTVCGSDGRSYPSVC 126
>gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]
Length = 480
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 14/80 (17%)
Query: 32 PCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELC-TERDPCDPHKGLFC--DFGSPA 88
P RCP +P C G + D CGCC VC G C + PC +GL C FG PA
Sbjct: 43 PARCPPQPE-HCEGGRAR--DACGCCEVCGAPEGAACGLQEGPCG--EGLQCVVPFGVPA 97
Query: 89 NRKI------GVCTAKDGAP 102
+ + G+C P
Sbjct: 98 SATVRRRAQAGLCVCASSEP 117
>gi|4504619 insulin-like growth factor binding protein 7 [Homo
sapiens]
Length = 282
Score = 42.7 bits (99), Expect = 5e-04
Identities = 41/122 (33%), Positives = 49/122 (40%), Gaps = 25/122 (20%)
Query: 12 AFVVLLALCSRPAVGQNCSGPCR---CPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELC 68
A ++LL L + + GPC CP P C G + D CGCC +CA+ GE C
Sbjct: 14 AGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETR--DACGCCPMCARGEGEPC 71
Query: 69 ----TERDPCDPHKGLFCDFGSPANRK------------IGVCTAKDGAP-CIFGGTVYR 111
R C P G+ C S RK GVC K P C GT Y
Sbjct: 72 GGGGAGRGYCAP--GMEC-VKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYP 128
Query: 112 SG 113
SG
Sbjct: 129 SG 130
>gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens]
Length = 476
Score = 42.7 bits (99), Expect = 5e-04
Identities = 28/64 (43%), Positives = 31/64 (48%), Gaps = 10/64 (15%)
Query: 21 SRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELC--TERDPCDPHK 78
S PAV Q P RCP P C G + V D C CCRVC E+C + PC P
Sbjct: 39 SCPAVCQ----PTRCP--ALPTCALGTTPVFDLCRCCRVCPAAEREVCGGAQGQPCAP-- 90
Query: 79 GLFC 82
GL C
Sbjct: 91 GLQC 94
>gi|22129776 HtrA serine peptidase 3 [Homo sapiens]
Length = 453
Score = 42.4 bits (98), Expect = 6e-04
Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 11 VAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELC 68
+A + LAL P C C P+PRCP G V D C CC VCA GE C
Sbjct: 8 LAALAALALAREPPAAP-CPARCDVSRCPSPRCPGGY--VPDLCNCCLVCAASEGEPC 62
>gi|208022668 endothelial cell-specific molecule 1 isoform b
precursor [Homo sapiens]
Length = 134
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/79 (34%), Positives = 31/79 (39%), Gaps = 11/79 (13%)
Query: 32 PCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELC------TERDPCDPHKGLFCDFG 85
P C P VLD CGCCRVCA GE C + C P GL C
Sbjct: 29 PQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGP--GLRCQPS 86
Query: 86 S---PANRKIGVCTAKDGA 101
+ P + G+C D A
Sbjct: 87 NGEDPFGEEFGICKEHDMA 105
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.139 0.475
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,737,047
Number of Sequences: 37866
Number of extensions: 901461
Number of successful extensions: 3355
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 2783
Number of HSP's gapped (non-prelim): 624
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.