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Search of human proteins with 4502629
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502629 cyclin T2 isoform a [Homo sapiens]
(663 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502629 cyclin T2 isoform a [Homo sapiens] 1335 0.0
gi|17978469 cyclin T2 isoform b [Homo sapiens] 1293 0.0
gi|17978466 cyclin T1 [Homo sapiens] 528 e-150
gi|150417989 cyclin K isoform 1 [Homo sapiens] 135 2e-31
gi|38176158 cyclin K isoform 2 [Homo sapiens] 135 2e-31
gi|88758580 cyclin L2 isoform A [Homo sapiens] 101 2e-21
gi|9945320 cyclin L1 [Homo sapiens] 100 3e-21
gi|196049382 family with sequence similarity 58, member A isofor... 85 2e-16
gi|221554516 cyclin L2 isoform C [Homo sapiens] 79 2e-14
gi|221554518 cyclin L2 isoform D [Homo sapiens] 78 3e-14
gi|88758578 cyclin L2 isoform B [Homo sapiens] 78 3e-14
gi|157502165 family with sequence similarity 58 member B [Homo s... 78 3e-14
gi|196049384 family with sequence similarity 58, member A isofor... 75 1e-13
gi|61676091 cyclin C isoform a [Homo sapiens] 74 4e-13
gi|60097902 filaggrin [Homo sapiens] 54 4e-07
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 50 5e-06
gi|57864582 hornerin [Homo sapiens] 50 9e-06
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 47 4e-05
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula... 47 4e-05
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula... 47 4e-05
gi|50962882 G patch domain containing 8 [Homo sapiens] 47 7e-05
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 46 1e-04
gi|113415504 PREDICTED: similar to ribonucleic acid binding prot... 46 1e-04
gi|169166499 PREDICTED: similar to ribonucleic acid binding prot... 46 1e-04
gi|113415498 PREDICTED: similar to ribonucleic acid binding prot... 46 1e-04
gi|88973230 PREDICTED: similar to ribonucleic acid binding prote... 46 1e-04
gi|61676093 cyclin C isoform b [Homo sapiens] 46 1e-04
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 45 2e-04
gi|221316599 chromogranin B precursor [Homo sapiens] 45 2e-04
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens] 45 2e-04
>gi|4502629 cyclin T2 isoform a [Homo sapiens]
Length = 663
Score = 1335 bits (3454), Expect = 0.0
Identities = 663/663 (100%), Positives = 663/663 (100%)
Query: 1 MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINT 60
MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINT
Sbjct: 1 MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINT 60
Query: 61 AIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDT 120
AIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDT
Sbjct: 61 AIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDT 120
Query: 121 KCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNS 180
KCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNS
Sbjct: 121 KCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNS 180
Query: 181 LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEF 240
LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEF
Sbjct: 181 LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEF 240
Query: 241 LQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPS 300
LQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPS
Sbjct: 241 LQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPS 300
Query: 301 FQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSART 360
FQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSART
Sbjct: 301 FQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSART 360
Query: 361 EQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHH 420
EQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHH
Sbjct: 361 EQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHH 420
Query: 421 GPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTS 480
GPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTS
Sbjct: 421 GPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTS 480
Query: 481 PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE 540
PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE
Sbjct: 481 PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE 540
Query: 541 GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLR 600
GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLR
Sbjct: 541 GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLR 600
Query: 601 SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGD 660
SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGD
Sbjct: 601 SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGD 660
Query: 661 QRS 663
QRS
Sbjct: 661 QRS 663
>gi|17978469 cyclin T2 isoform b [Homo sapiens]
Length = 730
Score = 1293 bits (3347), Expect = 0.0
Identities = 643/647 (99%), Positives = 644/647 (99%)
Query: 1 MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINT 60
MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINT
Sbjct: 1 MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINT 60
Query: 61 AIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDT 120
AIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDT
Sbjct: 61 AIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDT 120
Query: 121 KCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNS 180
KCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNS
Sbjct: 121 KCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNS 180
Query: 181 LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEF 240
LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEF
Sbjct: 181 LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEF 240
Query: 241 LQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPS 300
LQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPS
Sbjct: 241 LQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPS 300
Query: 301 FQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSART 360
FQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSART
Sbjct: 301 FQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSART 360
Query: 361 EQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHH 420
EQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHH
Sbjct: 361 EQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHH 420
Query: 421 GPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTS 480
GPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTS
Sbjct: 421 GPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTS 480
Query: 481 PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE 540
PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE
Sbjct: 481 PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE 540
Query: 541 GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLR 600
GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLR
Sbjct: 541 GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLR 600
Query: 601 SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTS 647
SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSG +S
Sbjct: 601 SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSS 647
>gi|17978466 cyclin T1 [Homo sapiens]
Length = 726
Score = 528 bits (1361), Expect = e-150
Identities = 318/652 (48%), Positives = 404/652 (61%), Gaps = 80/652 (12%)
Query: 8 SSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHR 67
+ RW+FTREQLEN+PSRR GV+ DKELS RQQAANL+Q+MGQRLNVSQLTINTAIVYMHR
Sbjct: 9 NKRWYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHR 68
Query: 68 FYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQ 127
FYM SFT+F N ++ ALFLAAKVEEQ +KLEHVIKVAH CLHP E L DT+ +AYLQ
Sbjct: 69 FYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQ 128
Query: 128 QTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFC 187
Q Q+LVILE+I+LQTLGFE+TI+HPHT VVKCTQLVRASKDLAQTSYFMATNSLHLTTF
Sbjct: 129 QVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFS 188
Query: 188 LQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKT 247
LQY P V+ACVCIHLACKWSNWEIPVSTDGKHWWEYVD TVTLELLDELTHEFLQILEKT
Sbjct: 189 LQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKT 248
Query: 248 PNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPSFQKPSTS 307
PNRLK+I NWRA +AA+K K D + ++ +++ S T + S +TS
Sbjct: 249 PNRLKRIWNWRACEAAKKTKADDRGTDEKTSEQTILNMISQSSSDTTIAGLMSMSTSTTS 308
Query: 308 AFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQK 367
A P+ +P++ +S NL TS + + W Q S + E +
Sbjct: 309 AVPS-LPVS--------EESSSNL---------TSVEMLPGKRWLSSQPSFKLEPTQGHR 350
Query: 368 QETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTP 427
+L+ +G+ H + ++ + Q+ K+ S
Sbjct: 351 TSENLA----------------LTGVDHSLPQDGSNAFISQKQNSKSVPS---------- 384
Query: 428 GIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIP 487
K+SL +YR K E + + A V+ Q+ S S + +K+P
Sbjct: 385 ----AKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKMP 440
Query: 488 I---ANTEKYMADKKEKSGSLKLRIPIPPTDKSASK--EELKMKIKV-SSSERHSSSDEG 541
I N E+ +K +K+ +LK+RIP+ DK+AS EE+KM+IKV +++++H+S ++
Sbjct: 441 IEGSENPERPFLEKADKT-ALKMRIPVAGGDKAASSKPEEIKMRIKVHAAADKHNSVEDS 499
Query: 542 SGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSS---------SGGSKHSAD 592
K SR+HKEKHK HPS+ HH +H HSH HS S G KHS+
Sbjct: 500 VTK--------SREHKEKHKTHPSNHHHHHNH-HSHKHSHSQLPVGTGNKRPGDPKHSSQ 550
Query: 593 GIPPTVLRSPVGLSSDGISSSSSSSRKR---LHVNDASHNHHSKMSKSSKSS 641
+ LSS SSSSS+RKR A +H +K++KS+KSS
Sbjct: 551 --TSNLAHKTYSLSSS--FSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSS 598
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 135 bits (339), Expect = 2e-31
Identities = 80/258 (31%), Positives = 142/258 (55%), Gaps = 21/258 (8%)
Query: 11 WFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYM 70
W++ ++ L +TPS+ G++ E R++ A I ++G RL + T+ T I+Y HRFYM
Sbjct: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYM 83
Query: 71 HHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQ-T 129
HSF +F + + + LFLA KVEE +K + +IK A + L+ D + +
Sbjct: 84 FHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLN------DVQFGQFGDDPK 137
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMA---TNSLHLTTF 186
+E+++LE I+LQT+ F++ +EHP+ ++K + ++ K+ Q MA N TT
Sbjct: 138 EEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTL 197
Query: 187 CLQYKPTVIACVCIHLACKWSNWEIPVSTDG---KHWWEYVDPTVTLELLDELTHEFL-- 241
LQ++P +IA ++LA + +EI T + WWE V +++L+++ H+ L
Sbjct: 198 SLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDL 257
Query: 242 ------QILEKTPNRLKK 253
Q+ TP++L++
Sbjct: 258 YSQGKQQMPHHTPHQLQQ 275
>gi|38176158 cyclin K isoform 2 [Homo sapiens]
Length = 354
Score = 135 bits (339), Expect = 2e-31
Identities = 80/258 (31%), Positives = 142/258 (55%), Gaps = 21/258 (8%)
Query: 11 WFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYM 70
W++ ++ L +TPS+ G++ E R++ A I ++G RL + T+ T I+Y HRFYM
Sbjct: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYM 83
Query: 71 HHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQ-T 129
HSF +F + + + LFLA KVEE +K + +IK A + L+ D + +
Sbjct: 84 FHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLN------DVQFGQFGDDPK 137
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMA---TNSLHLTTF 186
+E+++LE I+LQT+ F++ +EHP+ ++K + ++ K+ Q MA N TT
Sbjct: 138 EEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTL 197
Query: 187 CLQYKPTVIACVCIHLACKWSNWEIPVSTDG---KHWWEYVDPTVTLELLDELTHEFL-- 241
LQ++P +IA ++LA + +EI T + WWE V +++L+++ H+ L
Sbjct: 198 SLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDL 257
Query: 242 ------QILEKTPNRLKK 253
Q+ TP++L++
Sbjct: 258 YSQGKQQMPHHTPHQLQQ 275
>gi|88758580 cyclin L2 isoform A [Homo sapiens]
Length = 520
Score = 101 bits (252), Expect = 2e-21
Identities = 97/374 (25%), Positives = 162/374 (43%), Gaps = 34/374 (9%)
Query: 16 EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75
++L TPS G++ D E R LIQ G L + Q+ + T V RF+ SF
Sbjct: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
Query: 76 KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129
K + +S + LA+K+EE R++ VI V H P+ LLD Y+
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLD---QDYVNLK 173
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSYFMATNSLHLTTFC 187
+++ E +L+ LGF + ++HPH +V Q++ ++ L QTS+ +SL F
Sbjct: 174 NQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVF- 232
Query: 188 LQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKT 247
++++P IAC CI+LA + EIP+ + HW+ T +E+ L+IL+
Sbjct: 233 VRFQPESIACACIYLAAR--TLEIPL-PNRPHWFLLFGATE-----EEIQEICLKILQLY 284
Query: 248 PNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPSF-QKPST 306
+ + + RK ++ ++ L L + ++D +G P + P
Sbjct: 285 ARKKVDLTHLEGEVEKRKHAIEEAKAQARGL---LPGGTQVLDGTSGFSPAPKLVESPKE 341
Query: 307 SAFPAPVPLNSGNI-----SVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTE 361
P PL+ N + + ++ L G S S S Q + S
Sbjct: 342 GKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSY-----SRSPS 396
Query: 362 QLYSQKQETSLSGS 375
+ S K+ S SGS
Sbjct: 397 RSASPKRRKSDSGS 410
Score = 33.9 bits (76), Expect = 0.49
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 11/127 (8%)
Query: 519 SKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHS 578
S + K +++ + + S G K + S SR ++ + PS ++S K S
Sbjct: 351 SVKNTKRRLEGAKKAKADSPVNGLPKGRESRSR-SRSREQSYSRSPS---RSASPKRRKS 406
Query: 579 HSGSSSGGSK-----HSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
SGS+SGGSK S PP ++P G S K H S+
Sbjct: 407 DSGSTSGGSKSQSRSRSRSDSPPR--QAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSR 464
Query: 634 MSKSSKS 640
S S+S
Sbjct: 465 SSSRSRS 471
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 100 bits (250), Expect = 3e-21
Identities = 74/243 (30%), Positives = 121/243 (49%), Gaps = 18/243 (7%)
Query: 16 EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75
E+L TPS + G++ E R LIQ G L + Q+ + T V HRF+ SF
Sbjct: 62 ERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFV 121
Query: 76 KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129
K + I++ + LA+K+EE R++ VI V H P +LD Y+
Sbjct: 122 KHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQN---YINTK 178
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSYFMATNSLHLTTFC 187
+++ E +L+ LGF + ++HPH +V Q++ ++ L QT++ +SL F
Sbjct: 179 NQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVF- 237
Query: 188 LQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQI-LEK 246
++++P IAC CI+LA + +IP+ T HW+ T E + E+ E L++ K
Sbjct: 238 VRFQPETIACACIYLAAR--ALQIPLPT-RPHWFLLFG--TTEEEIQEICIETLRLYTRK 292
Query: 247 TPN 249
PN
Sbjct: 293 KPN 295
Score = 33.9 bits (76), Expect = 0.49
Identities = 55/232 (23%), Positives = 84/232 (36%), Gaps = 28/232 (12%)
Query: 440 REKRKLETLDLDVRDHYIAAQVEQQHKQGQSQ----AASSSSVTSPIKMKIPIANTEKYM 495
R+K E L+ +V +A Q + +G + A S+ SP P + E
Sbjct: 291 RKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASK--PSSPREVKA 348
Query: 496 ADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHS--SSDEGSGKSKHSSPHIS 553
+K S ++K P + ASK K S R+S +S S S H
Sbjct: 349 EEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTP 408
Query: 554 RDHKEKHKEHPS---------SRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVG 604
R H + SR H+ S + H+H GS +KH+ D + +
Sbjct: 409 RRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNH-GSPHLKAKHTRDDLKSSNRHGHKR 467
Query: 605 LSSDGISSSSS---SSRKRLHVNDASHNHHSK-------MSKSSKSSGGLRT 646
S S S S S + H ++ H+ + S SK GG R+
Sbjct: 468 KKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRS 519
>gi|196049382 family with sequence similarity 58, member A isoform 1
[Homo sapiens]
Length = 248
Score = 84.7 bits (208), Expect = 2e-16
Identities = 54/216 (25%), Positives = 110/216 (50%), Gaps = 15/216 (6%)
Query: 39 QAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQAR 98
+ A I E G +L + + I TA H+F+ + ++ +I+ ++++LA KVEEQ
Sbjct: 29 RVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHL 88
Query: 99 KLEHVIKVAHACLHPL-EPL-LDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDV 156
+ +I V++ +P EPL LD++ + + +V E +ML+ L F+++ +HPH +
Sbjct: 89 RTRDIINVSNRYFNPSGEPLELDSR---FWELRDSIVQCELLMLRVLRFQVSFQHPHKYL 145
Query: 157 VKCTQLVR--------ASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSN 208
+ ++ +A T++ + +S H CL+++ IA ++LA +
Sbjct: 146 LHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYH-GALCLRFQAQHIAVAVLYLALQVYG 204
Query: 209 WEIPVSTDG-KHWWEYVDPTVTLELLDELTHEFLQI 243
E+P + K WW+ + +T ++D + + +QI
Sbjct: 205 VEVPAEVEAEKPWWQVFNDDLTKPIIDNIVSDLIQI 240
>gi|221554516 cyclin L2 isoform C [Homo sapiens]
Length = 236
Score = 78.6 bits (192), Expect = 2e-14
Identities = 52/174 (29%), Positives = 85/174 (48%), Gaps = 11/174 (6%)
Query: 16 EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75
++L TPS G++ D E R LIQ G L + Q+ + T V RF+ SF
Sbjct: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
Query: 76 KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129
K + +S + LA+K+EE R++ VI V H P+ LLD Y+
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLD---QDYVNLK 173
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSYFMATNSL 181
+++ E +L+ LGF + ++HPH +V Q++ ++ L QTS+ + + L
Sbjct: 174 NQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWVASEDPL 227
>gi|221554518 cyclin L2 isoform D [Homo sapiens]
Length = 227
Score = 77.8 bits (190), Expect = 3e-14
Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 11/167 (6%)
Query: 16 EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75
++L TPS G++ D E R LIQ G L + Q+ + T V RF+ SF
Sbjct: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
Query: 76 KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129
K + +S + LA+K+EE R++ VI V H P+ LLD Y+
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLD---QDYVNLK 173
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSY 174
+++ E +L+ LGF + ++HPH +V Q++ ++ L QTS+
Sbjct: 174 NQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW 220
>gi|88758578 cyclin L2 isoform B [Homo sapiens]
Length = 226
Score = 77.8 bits (190), Expect = 3e-14
Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 11/167 (6%)
Query: 16 EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75
++L TPS G++ D E R LIQ G L + Q+ + T V RF+ SF
Sbjct: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
Query: 76 KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129
K + +S + LA+K+EE R++ VI V H P+ LLD Y+
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLD---QDYVNLK 173
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSY 174
+++ E +L+ LGF + ++HPH +V Q++ ++ L QTS+
Sbjct: 174 NQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW 220
>gi|157502165 family with sequence similarity 58 member B [Homo
sapiens]
Length = 252
Score = 77.8 bits (190), Expect = 3e-14
Identities = 57/218 (26%), Positives = 106/218 (48%), Gaps = 19/218 (8%)
Query: 39 QAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQAR 98
+ A I E G +L + + I TA +F+ F+ +I+ ++++LA KVEEQ
Sbjct: 33 RVARFIMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPL 92
Query: 99 KLEHVIKVAHACLHP-LEPL-LDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPH--- 153
+I V++ +P EPL LD++ + +V E +ML+ L F+++ +HPH
Sbjct: 93 WAHDIISVSNRYFNPSSEPLGLDSR---LWELRDSIVQRELLMLRVLRFQVSFQHPHKYL 149
Query: 154 -------TDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKW 206
+ + C R +A T++ + +S H CL+++ IA V ++LA +
Sbjct: 150 LYYLVSLKNWLNCHSWQRT--PVAVTAWALLRDSYH-GGLCLRFQAQHIAVVVLYLALQV 206
Query: 207 SNWEIPVSTDG-KHWWEYVDPTVTLELLDELTHEFLQI 243
E+P + K WW+ +T ++D + + +QI
Sbjct: 207 YGVEVPAEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQI 244
>gi|196049384 family with sequence similarity 58, member A isoform 2
[Homo sapiens]
Length = 228
Score = 75.5 bits (184), Expect = 1e-13
Identities = 50/195 (25%), Positives = 99/195 (50%), Gaps = 15/195 (7%)
Query: 39 QAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQAR 98
+ A I E G +L + + I TA H+F+ + ++ +I+ ++++LA KVEEQ
Sbjct: 29 RVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHL 88
Query: 99 KLEHVIKVAHACLHPL-EPL-LDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDV 156
+ +I V++ +P EPL LD++ + + +V E +ML+ L F+++ +HPH +
Sbjct: 89 RTRDIINVSNRYFNPSGEPLELDSR---FWELRDSIVQCELLMLRVLRFQVSFQHPHKYL 145
Query: 157 VKCTQLVR--------ASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSN 208
+ ++ +A T++ + +S H CL+++ IA ++LA +
Sbjct: 146 LHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYH-GALCLRFQAQHIAVAVLYLALQVYG 204
Query: 209 WEIPVSTDG-KHWWE 222
E+P + K WW+
Sbjct: 205 VEVPAEVEAEKPWWQ 219
>gi|61676091 cyclin C isoform a [Homo sapiens]
Length = 283
Score = 73.9 bits (180), Expect = 4e-13
Identities = 53/216 (24%), Positives = 98/216 (45%), Gaps = 26/216 (12%)
Query: 42 NLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEE------ 95
N+IQ +G+ L + Q I TA VY RFY +S + +++ T +FLA+KVEE
Sbjct: 46 NVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSN 105
Query: 96 --QARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPH 153
V+K + P E + + ++ E +L+ + + + HP+
Sbjct: 106 TRLIAAATSVLKTRFSYAFPKE---------FPYRMNHILECEFYLLELMDCCLIVYHPY 156
Query: 154 TDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPV 213
+++ Q + +D+ + N + T CL Y P +IA C+H+AC +
Sbjct: 157 RPLLQYVQDM-GQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVAC------VVQ 209
Query: 214 STDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPN 249
D + W + + +V +E + E+ L++ E+ N
Sbjct: 210 QKDARQW--FAELSVDMEKILEIIRVILKLYEQWKN 243
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 54.3 bits (129), Expect = 4e-07
Identities = 75/333 (22%), Positives = 121/333 (36%), Gaps = 25/333 (7%)
Query: 346 SSHQEWPQH-QDSARTEQLYSQKQETSLSGSQYNINFQ-QGPSISLHSGLHHRPDKISDH 403
SS Q +H + S+R + S +Q S +G ++ + Q Q S HSG+ H +
Sbjct: 1973 SSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVR 2032
Query: 404 SSVKQEYT-HKAGSSKHHGPISTTPGIIPQKMS---LDKYREKRKLETLDLDVRDHYIAA 459
S + Y+ +A S+ H S T + Q + ++E + ++ + R
Sbjct: 2033 DSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLY 2092
Query: 460 QVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSAS 519
QV + + S+ S A + +E +++ + S
Sbjct: 2093 QVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGS 2152
Query: 520 KEELKMKIKVSSSERHSS------SDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSH 573
+E + S HS SD G+S S SR +K + SRH S H
Sbjct: 2153 HQEQSVDRSGHSGSHHSHTTSQGRSDASRGQS--GSRSASRKTYDKEQSGDGSRHSGSHH 2210
Query: 574 KHSHSHSGSSSGGSKHSADGIPPTVLR---SPVGLSSDGISSSSSSSRKRLHVNDASHNH 630
+ S + SS P R S V SD S S R+ AS NH
Sbjct: 2211 HEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRS---GSASRNH 2267
Query: 631 HSKMSKSSKSSGGLRTSQHPRETGQEASGDQRS 663
H + S+ S+HPR ++ +G S
Sbjct: 2268 HGSAQEQSRDG-----SRHPRSHHEDRAGHGHS 2295
Score = 51.2 bits (121), Expect = 3e-06
Identities = 77/320 (24%), Positives = 117/320 (36%), Gaps = 46/320 (14%)
Query: 346 SSHQEWPQHQDSARTEQ-LYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHS 404
SS Q H +S+ Q + S +Q S G ++ QQ S HSG+ HR S
Sbjct: 1325 SSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHR-----QAS 1379
Query: 405 SVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQ 464
S ++ H+ S Q + + + E ++ V H A +Q
Sbjct: 1380 SAVRDSGHRGSSGS-------------QVTNSEGHSEDSDTQS----VSAHGQAGPHQQS 1422
Query: 465 HKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELK 524
HK+ + SS S + Y E+S S + + S+ E
Sbjct: 1423 HKESARGQSGESSGRS---------RSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHE-- 1471
Query: 525 MKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKE-KHKEHPSSRHHTSSHKHSHSHSGSS 583
+ +S RHS+S +G + P SR ++ + E R S + HSH+
Sbjct: 1472 ---QARNSSRHSASQDGQDTIR-GHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGR 1527
Query: 584 SGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGG 643
S S H G P + R G S S SR A + HS++ + S G
Sbjct: 1528 SDAS-HGQSG-PRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQG--ESAG 1583
Query: 644 LRTSQHPRETGQEASGDQRS 663
+TS R G S D+ S
Sbjct: 1584 SKTS---RRQGSSVSQDRDS 1600
Score = 50.1 bits (118), Expect = 7e-06
Identities = 71/346 (20%), Positives = 124/346 (35%), Gaps = 29/346 (8%)
Query: 324 DSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQ 383
+ H+ D+ + +G + SHQE + + R+ + S + S + +
Sbjct: 751 EGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWT 810
Query: 384 GPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHG-PISTTPGIIPQKMSLDKYREK 442
GPS + G HH + + S Q+ G G P S+ G + E+
Sbjct: 811 GPSTGVRQGSHHEQARDNSRHSASQD-----GQDTIRGHPGSSRRG------RQGSHHEQ 859
Query: 443 RKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKS 502
+ + +Q +GQS + S+S T + + ++ + ++
Sbjct: 860 SVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS---RDGSRHSGSRHHEA 916
Query: 503 GSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKE 562
S + S+ + + SS + S S+ S S+ S SR+H+ +E
Sbjct: 917 SSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQE 976
Query: 563 -------HPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSS 615
HP S HH H HS S G+ H+ T S + SS
Sbjct: 977 QSRHGSRHPRS-HHEDRAGHGHSADSSRQSGTPHA-----ETSSGGQAASSHEQARSSPG 1030
Query: 616 SSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQ 661
H A + HS + + SS +R S H +G +AS +
Sbjct: 1031 ERHGSRHQQSADSSRHSGIPRRQASS-AVRDSGHWGSSGSQASDSE 1075
Score = 48.5 bits (114), Expect = 2e-05
Identities = 73/356 (20%), Positives = 124/356 (34%), Gaps = 43/356 (12%)
Query: 321 SVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNIN 380
S + H+ D+ + + SH+E + Q + + S + S + +
Sbjct: 2045 SDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTH 2104
Query: 381 FQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYR 440
Q PS G H+ + S S QE H GP Q+ S+D+
Sbjct: 2105 GQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRG--HPGPSRGGRQGSHQEQSVDRSG 2162
Query: 441 EKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKE 500
+ + +Q +GQS + S+S T K + ++
Sbjct: 2163 HSGSHHS--------HTTSQGRSDASRGQSGSRSASRKTYD---KEQSGDGSRHSGSHHH 2211
Query: 501 KSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKH 560
++ S + S + + SS + S S+ S S+ S SR+H
Sbjct: 2212 EASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSA 2271
Query: 561 KE-------HPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSS 613
+E HP S HH H HS S G+ H+ +S G ++
Sbjct: 2272 QEQSRDGSRHPRS-HHEDRAGHGHSAESSRQSGTHHAE--------------NSSGGQAA 2316
Query: 614 SSSSRKRLHVNDASHNHHSKMSKSSKSSG--------GLRTSQHPRETGQEASGDQ 661
SS + R + +HH + + SS+ SG +R S H +G +AS +
Sbjct: 2317 SSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSE 2372
Score = 47.8 bits (112), Expect = 3e-05
Identities = 80/356 (22%), Positives = 133/356 (37%), Gaps = 53/356 (14%)
Query: 325 SHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQG 384
S SD S+ A G SHQE + + + R+ + S + S + + + G
Sbjct: 2375 SEDSDTQSVSAHGQAGPHQ--QSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTG 2432
Query: 385 PSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHG-PISTTPGIIPQKMSLDKYREKR 443
S G HH+ + S S QE G HG P S++ G R+
Sbjct: 2433 TSTGGRQGSHHKQARDSSRHSTSQE-----GQDTIHGHPGSSSGG-----------RQGS 2476
Query: 444 KLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSG 503
E L +D R + + QG+S A+ S + + ++ D SG
Sbjct: 2477 HYEQL-VD-RSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQ---TRNDEQSGDGSRHSG 2531
Query: 504 SLKLRIPIPPTDKSASKEELKMKIKVSSSERH---SSSDEGSGKSKHSSPHISRDHKEKH 560
S +++S+ + +V + +S + GS S+ S + E+
Sbjct: 2532 SRH--------HEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERW 2583
Query: 561 KEHPSSRHHTSSH-------KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSS 613
S HH S+ +H SH G HSAD + R +S G ++
Sbjct: 2584 SGSASRNHHGSAQEQLRDGSRHPRSHQ-EDRAGHGHSADSSRQSGTRHT--QTSSGGQAA 2640
Query: 614 SSSSRKRLHVNDASHNHHSKMSKSSKSSG--------GLRTSQHPRETGQEASGDQ 661
SS + R + +HH + + SS+ SG +R S H +G +AS ++
Sbjct: 2641 SSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNE 2696
Score = 47.4 bits (111), Expect = 4e-05
Identities = 82/380 (21%), Positives = 132/380 (34%), Gaps = 72/380 (18%)
Query: 346 SSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGL-HHRPDK---IS 401
S H + + + S Q S S+ N +Q S HSG HH P S
Sbjct: 1512 SGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSS 1571
Query: 402 DHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYRE--KRKLETLDLDVRDHYIAA 459
HS V Q + + +S+ G + Q + + E +R+ E+ R+HY +A
Sbjct: 1572 RHSQVGQGESAGSKTSRRQG------SSVSQDRDSEGHSEDSERRSESAS---RNHYGSA 1622
Query: 460 QVEQQH-------------KQGQSQAASSSSVTSPIKMKI---PIANTEKYMADKKEKSG 503
+ + +H G S +S S T + ++ E+ + E+ G
Sbjct: 1623 REQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHG 1682
Query: 504 SLKLRIPIPPTDKSASKEELKMKI-----------KVSSSERHSSSDEGSGKSKH--SSP 550
S + TD + + + + S SE HS + S H + P
Sbjct: 1683 SRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGP 1742
Query: 551 HISRDHKEKHKEHPSSR--------HHTSSHKHS---HSHSGSSSGG------------S 587
H + H+E + R + S+H+ S H +G S+GG S
Sbjct: 1743 H-QQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSS 1801
Query: 588 KHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSK----SSGG 643
+HSA +R G S G S + SH+ H+ + S SG
Sbjct: 1802 RHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGS 1861
Query: 644 LRTSQHPRETGQEASGDQRS 663
S+ R Q G + S
Sbjct: 1862 RSVSRQTRNEKQSGDGSRHS 1881
Score = 47.0 bits (110), Expect = 6e-05
Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 36/338 (10%)
Query: 346 SSHQEWPQH-QDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHS 404
SS Q H ++S+ + S +Q S +G ++ + QQ S HSG+ H S
Sbjct: 2298 SSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH-----GQAS 2352
Query: 405 SVKQEYTHKAGS------SKHHGPISTTPGIIPQKMS---LDKYREKRKLETLDLDVRDH 455
S ++ H+ S S+ H S T + + ++E + + R
Sbjct: 2353 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 2412
Query: 456 YIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTD 515
QV H+Q +S + + T + + K D S S + + I
Sbjct: 2413 SFLYQVST-HEQSESAHGRTGTSTGGRQ-----GSHHKQARDSSRHSTSQEGQDTIHGHP 2466
Query: 516 KSASK-------EELKMKIKVSSSERHSSSDEGSGKSKHS---SPHISRDHKEKHKEHPS 565
S+S E+L + S S ++ +G + H S SR + +
Sbjct: 2467 GSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDG 2526
Query: 566 SRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVND 625
SRH S H + S + SS P R+ S S S
Sbjct: 2527 SRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGS 2586
Query: 626 ASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQRS 663
AS NHH + + S+HPR ++ +G S
Sbjct: 2587 ASRNHHGSAQEQLRDG-----SRHPRSHQEDRAGHGHS 2619
Score = 47.0 bits (110), Expect = 6e-05
Identities = 76/356 (21%), Positives = 133/356 (37%), Gaps = 26/356 (7%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG+ S SDN S + +S+H + HQ S + + + SGS
Sbjct: 3005 DSGHRGYSGSQASDNEGH---SEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGS 3061
Query: 376 -QYNIN-FQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQK 433
Y ++ +Q S +G R + S H + H A S I PG +
Sbjct: 3062 FLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSA-SQYGQDTIRGHPG--SSR 3118
Query: 434 MSLDKYREKRKLETLDLDVRDH-YIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTE 492
Y + +++ H + +Q +GQS + S+S T + ++
Sbjct: 3119 GGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS---GDSS 3175
Query: 493 KYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHI 552
++ + ++ + + S+ + + + SS + S S+ S S+ S
Sbjct: 3176 RHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSA 3235
Query: 553 SRDHKEKHKE-------HPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGL 605
SR+H+ +E HP S HH H HS S G++H+ T
Sbjct: 3236 SRNHRGSVQEQSRHGSRHPRS-HHEDRAGHGHSADRSRQSGTRHA-----ETSSGGQAAS 3289
Query: 606 SSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQ 661
S + SS H A + HS + + SS +R S+H +G +AS +
Sbjct: 3290 SHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASS-AVRDSRHWGSSGSQASDSE 3344
Score = 46.6 bits (109), Expect = 7e-05
Identities = 79/371 (21%), Positives = 131/371 (35%), Gaps = 56/371 (15%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG+ S SDN S + +S+H + HQ S + + + SGS
Sbjct: 2681 DSGHRGYSGSQASDNEGH---SEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGS 2737
Query: 376 -QYNIN-FQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQK 433
Y ++ +Q S +G R + S H + H A S I PG +
Sbjct: 2738 FLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSA-SQDGQDTIRGHPG--SSR 2794
Query: 434 MSLDKYREKRKLETLDLDVRDH-YIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTE 492
Y + +++ H + +Q +GQS + S+S T E
Sbjct: 2795 GGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTT----------RNE 2844
Query: 493 KYMADKKEKSGS----------LKLRIPIPPTDKSASKEELKMKIKVSS---SERHS-SS 538
+ D SGS + S+ + VS SE HS S
Sbjct: 2845 EQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDS 2904
Query: 539 DEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTV 598
+ SG + + +++ HP S H H HS S G++H+
Sbjct: 2905 ERWSGSASRNHHGSAQEQLRDGSRHPRS-HQEDRAGHGHSADSSRQSGTRHTQ------- 2956
Query: 599 LRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSG--------GLRTSQHP 650
+S G ++SS + R + +HH + + SS+ SG +R S H
Sbjct: 2957 -------TSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHR 3009
Query: 651 RETGQEASGDQ 661
+G +AS ++
Sbjct: 3010 GYSGSQASDNE 3020
Score = 46.6 bits (109), Expect = 7e-05
Identities = 75/341 (21%), Positives = 120/341 (35%), Gaps = 49/341 (14%)
Query: 325 SHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQG 384
S SD S+ A G SHQE + + + R+ + S + S + + + G
Sbjct: 3671 SEDSDTQSVSAHGQAGPHQ--QSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAG 3728
Query: 385 PSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRK 444
PS G H + S S QE G G + G Y E+
Sbjct: 3729 PSTGGRQGSRHEQARDSSRHSASQE-----GQDTIRGHPGSRRG-----GRQGSYHEQSV 3778
Query: 445 LETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGS 504
+ + +Q GQS + S+S T E+ D SGS
Sbjct: 3779 DRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRET----------RNEEQSGDGSRHSGS 3828
Query: 505 LKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHP 564
R T +S+ + + + S R S +GS S+ S + E+ E
Sbjct: 3829 ---RHHEASTQADSSRHSQSGQGESAGSRR--SRRQGSSVSQDSDSEAYPEDSERRSESA 3883
Query: 565 SSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVN 624
S HH SS + S GS GS H + + S + S SS++++
Sbjct: 3884 SRNHHGSSRE--QSRDGSRHPGSSHR---------DTASHVQSSPVQSDSSTAKE----- 3927
Query: 625 DASHNHHSKMSKSSKSSGGLRTSQHPRETGQ---EASGDQR 662
H H S +S+ S G+++ P + ++ G +R
Sbjct: 3928 ---HGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTER 3965
Score = 46.2 bits (108), Expect = 1e-04
Identities = 79/346 (22%), Positives = 114/346 (32%), Gaps = 47/346 (13%)
Query: 340 STSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLH-HRPD 398
S+ + +S H E H D +R Q + E S + QG S+S S H D
Sbjct: 3174 SSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRR------QGSSVSQDSDSEGHSED 3227
Query: 399 KISDHSSVKQEYTHKAGSSKHHG---PISTTPGIIPQKMSLDKYREK--RKLETLDLDVR 453
S + + HG P S S D+ R+ R ET
Sbjct: 3228 SERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSS---- 3283
Query: 454 DHYIAAQVEQQHKQGQSQAAS------SSSVTSPIKMKIPIANTEKYMADKKE--KSGSL 505
Q H+Q +S S S IP + D + SGS
Sbjct: 3284 ----GGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGS- 3338
Query: 506 KLRIPIPPTDKSASKEELKMKIKVSS---------SERHSSSDEGSGKSKHSSPHISRDH 556
+D EE + VS S + S+ D G+S S + +
Sbjct: 3339 ------QASDSEGHSEESDTQ-SVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVS 3391
Query: 557 KEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSS-S 615
+ E R TS+ + SH + S+HSA +R G S G S
Sbjct: 3392 THEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYE 3451
Query: 616 SSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRET-GQEASGD 660
S R + + H+H + +S S G + R+T E SGD
Sbjct: 3452 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGD 3497
Score = 46.2 bits (108), Expect = 1e-04
Identities = 35/141 (24%), Positives = 58/141 (41%), Gaps = 24/141 (17%)
Query: 530 SSSERHSS-SDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSK 588
S S+ HS S+ SG + + +++ HP+S HH H HS S G+
Sbjct: 3543 SDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTS-HHEDRAGHGHSAESSRQSGTH 3601
Query: 589 HSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSG------ 642
H+ +S G ++SS + R + +HH + + SS+ SG
Sbjct: 3602 HAE--------------NSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQA 3647
Query: 643 --GLRTSQHPRETGQEASGDQ 661
+R S H +G +AS +
Sbjct: 3648 SSAVRDSGHRGSSGSQASDSE 3668
Score = 43.9 bits (102), Expect = 5e-04
Identities = 65/324 (20%), Positives = 107/324 (33%), Gaps = 9/324 (2%)
Query: 346 SSHQEWPQHQDSARTEQLYS-QKQETSLSGSQYNINFQQGPSISLHSGLHHRPDK-ISDH 403
SS Q +H +++ Q S Q+Q S G ++ QQ S SG R D +
Sbjct: 1649 SSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGD 1708
Query: 404 SSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS---LDKYREKRKLETLDLDVRDHYIAAQ 460
S + +A S+ H S T + + ++E + ++ + R Q
Sbjct: 1709 SGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQ 1768
Query: 461 VEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASK 520
V + + + S + + A + +E +++ + S
Sbjct: 1769 VSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH 1828
Query: 521 EELKMKIKVSSSERHS--SSDEGSGKSK--HSSPHISRDHKEKHKEHPSSRHHTSSHKHS 576
E + S HS +S E S S+ S +SR + + + SRH S H +
Sbjct: 1829 YEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEA 1888
Query: 577 HSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSK 636
S + SS P R+ S S S AS NH +
Sbjct: 1889 SSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWE 1948
Query: 637 SSKSSGGLRTSQHPRETGQEASGD 660
S+ S H G S D
Sbjct: 1949 QSRDGSRHPGSHHEDRAGHGHSAD 1972
Score = 43.1 bits (100), Expect = 8e-04
Identities = 92/391 (23%), Positives = 128/391 (32%), Gaps = 64/391 (16%)
Query: 317 SGNISVQDSHTSDNLSMLATGMPSTSYGLS-----SHQEWPQHQDSARTEQLYSQKQETS 371
SG+ SHT+ G S+G S S Q + Q T S+ E S
Sbjct: 539 SGHSGSHHSHTTSQ------GRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEAS 592
Query: 372 LSG-----SQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTT 426
SQ GP S + G D S S E + S HHG
Sbjct: 593 SQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSA--- 649
Query: 427 PGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQ----HKQGQS--QAASSSSVTS 480
Q+ S D R R D H +A ++ H Q S QAASS
Sbjct: 650 -----QEQSRDGSRHPRSHHE---DRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQAR 701
Query: 481 PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE 540
+ + + AD SG+ + D S + + SE HS +
Sbjct: 702 SSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRD---SGHRGSSGSQATDSEGHSEDSD 758
Query: 541 GSGKSKHSSP-HISRDHKEKHKEHPSSR--------HHTSSHKHS---HSHSGSSSG--- 585
S H H + H+E ++ R + S+HK S H +G S+G
Sbjct: 759 TQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQ 818
Query: 586 ---------GSKHSADGIPPTVLRSPVGLSSDGISSS-SSSSRKRLHVNDASHNHHSKMS 635
S+HSA +R G S G S S R + + H+H +
Sbjct: 819 GSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQG 878
Query: 636 KSSKS---SGGLRTSQHPRETGQEASGDQRS 663
+S S SG S+ R Q G + S
Sbjct: 879 RSDASRGQSGSRSASRTTRNEEQSRDGSRHS 909
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/136 (25%), Positives = 53/136 (38%), Gaps = 4/136 (2%)
Query: 532 SERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSA 591
S + S+ D G+S S I + + E R TS+ + SH + S+HSA
Sbjct: 1098 SHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSA 1157
Query: 592 DGIPPTVLRSPVGLSSDGISSS-SSSSRKRLHVNDASHNHHSKMSKSSKS---SGGLRTS 647
+R+ G G S S R + + H+H + +S S SG S
Sbjct: 1158 SQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSAS 1217
Query: 648 QHPRETGQEASGDQRS 663
+ R+ Q G + S
Sbjct: 1218 RQTRKDKQSGDGSRHS 1233
Score = 40.4 bits (93), Expect = 0.005
Identities = 39/141 (27%), Positives = 55/141 (39%), Gaps = 19/141 (13%)
Query: 530 SSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHP--SSRHHTSSHK----HSHSHSGSS 583
SS + S S S S+ S SR+H+ +E SRH TS H+ H HS S
Sbjct: 3537 SSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSR 3596
Query: 584 SGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGG 643
G+ H+ + S +SS +R SH+ S S G
Sbjct: 3597 QSGTHHAENS------------SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 3644
Query: 644 LRTSQHPRETGQE-ASGDQRS 663
+ S R++G +SG Q S
Sbjct: 3645 GQASSAVRDSGHRGSSGSQAS 3665
Score = 39.7 bits (91), Expect = 0.009
Identities = 84/352 (23%), Positives = 127/352 (36%), Gaps = 56/352 (15%)
Query: 317 SGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQET------ 370
SG+ Q S + S PST S E Q +DS+R + Q+T
Sbjct: 1762 SGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHE--QARDSSR-HSASQEGQDTIRGHPG 1818
Query: 371 SLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGII 430
S G + +++Q S HSG HH + S V + G S G S +
Sbjct: 1819 SSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSR------GQS---GSRSVSRQTR 1869
Query: 431 PQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQ-QHKQ-GQSQAASSSSVTSPIKMKIPI 488
+K S D R R H +++ + +H Q GQ Q++ + +
Sbjct: 1870 NEKQSGDGSRHSGS--------RHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQD 1921
Query: 489 ANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVS-SSERHSSSDEGSGKSKH 547
++++ + D + SGS AS+ L + S RH S
Sbjct: 1922 SDSQGHSEDSERWSGS-------------ASRNHLGSAWEQSRDGSRHPGSHHEDRAGHG 1968
Query: 548 SSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSS 607
S SR +H E S SSH+ + S +G GS H L+S
Sbjct: 1969 HSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERH-GSHHQ--------LQSADSSRH 2019
Query: 608 DGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASG 659
GI +SS V D+ H +S S++S S G S + Q +G
Sbjct: 2020 SGIGHGQASSA----VRDSGHRGYSG-SQASDSEGHSEDSDTQSVSAQGKAG 2066
Score = 39.7 bits (91), Expect = 0.009
Identities = 81/363 (22%), Positives = 115/363 (31%), Gaps = 73/363 (20%)
Query: 346 SSHQEWPQHQDSA-RTEQLYSQKQETSLSGSQYNINFQQGPSI--SLHSGLHHRPDKISD 402
S H++ H SA R+ Q ++ ETS SG Q + +Q S H H + S
Sbjct: 3256 SHHEDRAGHGHSADRSRQSGTRHAETS-SGGQAASSHEQARSSPGERHGSRHQQSADSSR 3314
Query: 403 HSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVE 462
HS + + A H S + Q + + E+ ++ V H A +
Sbjct: 3315 HSGIPRGQASSAVRDSRHWGSSGS-----QASDSEGHSEESDTQS----VSGHGQAGPHQ 3365
Query: 463 QQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEE 522
Q H++ + S S + Y E+S S R + S E
Sbjct: 3366 QSHQESARDRSGGRSGRS---------GSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHE 3416
Query: 523 LKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHS---- 578
+ S RHS+S EG + R + H E R S HSH+
Sbjct: 3417 -----QARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQG 3471
Query: 579 -------HSGSSSG------------GSKHS----------ADGI------------PPT 597
SGS S GS+HS AD P T
Sbjct: 3472 RSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRT 3531
Query: 598 VLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEA 657
+S D S S +R AS NH + S+ TS H G
Sbjct: 3532 SRNQGSSVSQDSDSQGHSEDSERWS-GSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGH 3590
Query: 658 SGD 660
S +
Sbjct: 3591 SAE 3593
Score = 39.3 bits (90), Expect = 0.012
Identities = 40/159 (25%), Positives = 64/159 (40%), Gaps = 26/159 (16%)
Query: 528 KVSSSERHSSSDEGSGKSKHSSPHI-SRDHKEKHKEHP--------SSRHHTSSHKH--- 575
+ S SE HS + + S H + + H+E + SS + S+H+
Sbjct: 421 QASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDS 480
Query: 576 SHSHSGSSSGG------------SKHSADGIPPTVLRSPVGLSSDGISSS-SSSSRKRLH 622
+H +G+S+GG S+HSA +R G S G S S R
Sbjct: 481 AHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSG 540
Query: 623 VNDASHNHHSKMSKSSKSSGGLRTSQHPRET-GQEASGD 660
+ + H+H + +S S G + R+T +E SGD
Sbjct: 541 HSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGD 579
Score = 39.3 bits (90), Expect = 0.012
Identities = 33/133 (24%), Positives = 47/133 (35%), Gaps = 8/133 (6%)
Query: 530 SSSERHSSSDEG-SGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSK 588
S SERHS E SG + + SR+ HP H H HS S G+
Sbjct: 1274 SDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGF-HQEDRASHGHSADSSRQSGTH 1332
Query: 589 HSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQ 648
H+ + S + SS H A + HS + SS +R S
Sbjct: 1333 HTESSSHGQAVS-----SHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASS-AVRDSG 1386
Query: 649 HPRETGQEASGDQ 661
H +G + + +
Sbjct: 1387 HRGSSGSQVTNSE 1399
Score = 38.9 bits (89), Expect = 0.015
Identities = 77/343 (22%), Positives = 122/343 (35%), Gaps = 45/343 (13%)
Query: 346 SSHQEWPQH-QDSARTEQLYSQKQETSLSGSQYNINFQ-QGPSISLHSGLHHRPDKISDH 403
SS + +H Q+S+ + S +Q S +G ++ Q Q S HSG H
Sbjct: 676 SSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGH-----GQA 730
Query: 404 SSVKQEYTHKAGS------SKHHGPISTTPGIIPQKMS---LDKYREKRKLETLDLDVRD 454
SS ++ H+ S S+ H S T + + ++E + + + R
Sbjct: 731 SSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRS 790
Query: 455 HYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPI--- 511
QV HKQ +S + T + + + D S S + I
Sbjct: 791 GSFLYQVST-HKQSESSHGWTGPSTG-----VRQGSHHEQARDNSRHSASQDGQDTIRGH 844
Query: 512 ---PPTDKSASKEELKMKIKVSSSERHSS------SDEGSGKSKHSSPHISRDHKEKHKE 562
+ S E + S HS SD G+S S SR + + +
Sbjct: 845 PGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQS--GSRSASRTTRNEEQS 902
Query: 563 HPSSRHHTSSHKHSHSHSGSS--SGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKR 620
SRH S H + SH+ S S + ++G T R +S D S S +R
Sbjct: 903 RDGSRHSGSRHHEASSHADISRHSQAGQGQSEG-SRTSRRQGSSVSQDSDSEGHSEDSER 961
Query: 621 LHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQRS 663
AS NH + S+ S+HPR ++ +G S
Sbjct: 962 WS-GSASRNHRGSAQEQSRHG-----SRHPRSHHEDRAGHGHS 998
Score = 37.4 bits (85), Expect = 0.045
Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 13/133 (9%)
Query: 530 SSSERHSS----SDEGSGKSKHSSPHISRD-HKEKHKEHPSSRHHTSSHKHSHSHSGSSS 584
+ S RHS GS S+H +S+D E+H + ++S H S S
Sbjct: 1244 ADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSR 1303
Query: 585 GGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGL 644
GS+H +S G S+ SS H +SH + ++SS G
Sbjct: 1304 DGSRHPG--------FHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGE 1355
Query: 645 RTSQHPRETGQEA 657
R +++ +
Sbjct: 1356 RHGSRHQQSADSS 1368
Score = 37.0 bits (84), Expect = 0.058
Identities = 63/299 (21%), Positives = 117/299 (39%), Gaps = 49/299 (16%)
Query: 373 SGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQ 432
SG+ + G + S H P + H S Q+ A SS+H G IP+
Sbjct: 1005 SGTPHAETSSGGQAASSHEQARSSPGE--RHGSRHQQ---SADSSRHSG--------IPR 1051
Query: 433 KMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIK----MKIPI 488
+ + R+ H+ ++ + +G S+ + + SV+ + +
Sbjct: 1052 RQASSAVRDS-----------GHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQ 1100
Query: 489 ANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGS-GKSKH 547
+ + + +SGS ++ +SA + + S+ R S E + S+H
Sbjct: 1101 ESARDWSGGRSGRSGSFIYQVSTHEQSESAHG-----RTRTSTGRRQGSHHEQARDSSRH 1155
Query: 548 SSPHISRDHKEKHKEHPSSRH---HTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVG 604
S+ S++ ++ + HP SR S H+ S SG S H+ + RS
Sbjct: 1156 SA---SQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTT-----SQGRSD-- 1205
Query: 605 LSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQRS 663
+S G S S S+SR+ + S+ +++ +S+H + GQE S R+
Sbjct: 1206 -ASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRH-SQVGQEQSSGSRT 1262
Score = 36.6 bits (83), Expect = 0.076
Identities = 33/130 (25%), Positives = 48/130 (36%), Gaps = 13/130 (10%)
Query: 532 SERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSA 591
SERHS S + ++ H S + + HP S H H HS S G++H+
Sbjct: 310 SERHSGS---ASRNHHGS---AWEQSRDGSRHPRS-HDEDRASHGHSADSSRQSGTRHA- 361
Query: 592 DGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPR 651
T R S + SS H A + HS + SS + H
Sbjct: 362 ----ETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASS-AVSDRGHRG 416
Query: 652 ETGQEASGDQ 661
+G +AS +
Sbjct: 417 SSGSQASDSE 426
Score = 33.9 bits (76), Expect = 0.49
Identities = 43/149 (28%), Positives = 58/149 (38%), Gaps = 25/149 (16%)
Query: 531 SSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHT-----SSHKHSHSHSGSS-- 583
S+ R + D+ SG S H H E SSRH SS + H GSS
Sbjct: 1215 SASRQTRKDKQSGDG---SRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVS 1271
Query: 584 --SGGSKHSADG--IPPTVLRSPVGLSSDGISSSSSSSRKRLHVND-ASHNHHSKMSKSS 638
S +HS D + + R+ G S + S S H D ASH H + S+ S
Sbjct: 1272 QDSDSERHSDDSERLSGSASRNHHGSSRE--QSRDGSRHPGFHQEDRASHGHSADSSRQS 1329
Query: 639 ------KSSGGLRTSQHPRETGQEASGDQ 661
SS G S H E + + G++
Sbjct: 1330 GTHHTESSSHGQAVSSH--EQARSSPGER 1356
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 50.4 bits (119), Expect = 5e-06
Identities = 53/154 (34%), Positives = 64/154 (41%), Gaps = 35/154 (22%)
Query: 506 KLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPS 565
K RI IP +S+ +MK SS +R SS S S HSS RD + K+ S
Sbjct: 456 KRRILIPSDIESSKSSTRRMK---SSCDRERSSRSSSLSSHHSS---KRDWSKSDKDVQS 509
Query: 566 SRHHTSSHKH-SHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVN 624
S H+S + S SHS S S GS S S SSS SR R
Sbjct: 510 SLTHSSRDSYRSKSHSQSYSRGSSRSRTA-----------------SKSSSHSRSR---- 548
Query: 625 DASHNHHSKMSKSSKSSGGLRTSQHPRETGQEAS 658
SK SSKS R S+ PR+T + S
Sbjct: 549 -------SKSRSSSKSGHRKRASKSPRKTASQLS 575
Score = 41.2 bits (95), Expect = 0.003
Identities = 70/321 (21%), Positives = 119/321 (37%), Gaps = 41/321 (12%)
Query: 340 STSYGLSSH----QEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHH 395
S S LSSH ++W + ++ +S + S ++ ++ +G S S
Sbjct: 485 SRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRD--SYRSKSHSQSYSRGSSRS------R 536
Query: 396 RPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDH 455
K S HS + + + + S H S +P ++S +K V+
Sbjct: 537 TASKSSSHSRSRSK-SRSSSKSGHRKRASKSPRKTASQLSENK------------PVKTE 583
Query: 456 YIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANT---EKYMADKKEKSGSLKLR---- 508
+ A + Q + + P+ P + +K E+ +K +
Sbjct: 584 PLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHL 643
Query: 509 IPIPPTDKSASKEELKMKIKVSSSERHSSSDEG-----SGKSKHSSPHI-SRDHKEKH-- 560
+PI T A+ +E E++S SD+ S +S SSP SR + +
Sbjct: 644 LPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYS 703
Query: 561 KEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKR 620
+ + SR SSH S S S S +K+S D + S +SSD + R
Sbjct: 704 RSYTRSRSLASSHSRSRSPSSRSHSRNKYS-DHSQCSRSSSYTSISSDDGRRAKRRLRSS 762
Query: 621 LHVNDASHNHHSKMSKSSKSS 641
N SH HS S+ + S
Sbjct: 763 GKKNSVSHKKHSSSSEKTLHS 783
Score = 39.3 bits (90), Expect = 0.012
Identities = 50/230 (21%), Positives = 79/230 (34%), Gaps = 22/230 (9%)
Query: 453 RDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRI--P 510
+D A+ G+ + A S + K P+ A S ++++++
Sbjct: 1194 QDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTT 1253
Query: 511 IPPTDKSASKEELKMKIKVSSSE-----------------RHSSSDEGSGKSKHSSPHIS 553
+P + E+K K KV + SSSDE + S+
Sbjct: 1254 VPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQT-PSRDDDSQSR 1312
Query: 554 RDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSS 613
+ + K SRH T S +SHS S S S S + + + R SS
Sbjct: 1313 SPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSS 1372
Query: 614 SSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQRS 663
S S K + S + S S+S S + R + S QRS
Sbjct: 1373 SYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRS--QRS 1420
Score = 35.8 bits (81), Expect = 0.13
Identities = 75/338 (22%), Positives = 133/338 (39%), Gaps = 44/338 (13%)
Query: 279 GSSLVQNSILVDSVTGVPTNPSFQKPSTSAFPAPVPLNSGNISVQDSHT-SDNLSMLATG 337
GSS + +S + T + S+ + P +S + S S+T S +L+ +
Sbjct: 659 GSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSR 718
Query: 338 MPSTSYGLSSHQEWPQHQDSARTEQLYS--------QKQETSLSGSQYNINFQQGPSISL 389
S S S ++ H +R+ S K+ SG + +++ ++ S S
Sbjct: 719 SRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSS- 777
Query: 390 HSGLHHRPDKISDHSSVKQEY--------------------THKAGSSKHHGPISTTPGI 429
LH + K D SS ++Y T A + G + T
Sbjct: 778 EKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNK 837
Query: 430 IPQKMSLDKYREKR-----KLETLDLDVRDHYI-AAQVEQQHKQGQ---SQAASSSSVTS 480
+ +K + +R K TL ++ DH ++ ++++ G S++ S VT
Sbjct: 838 QEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTK 897
Query: 481 PIKMKI-PIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKV--SSSERHSS 537
K P ++ E+ A +S ++ I + PT KS++ L SS +R S+
Sbjct: 898 NSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTST 957
Query: 538 SD-EGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHK 574
SD EGS + ++ + HK KE+ R HT K
Sbjct: 958 SDSEGSCSNSENNRGKPQKHKHGSKEN-LKREHTKKVK 994
Score = 33.9 bits (76), Expect = 0.49
Identities = 64/288 (22%), Positives = 110/288 (38%), Gaps = 43/288 (14%)
Query: 391 SGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDL 450
S +H+ +K S+ S + Y+ + S P S + + S Y R L +
Sbjct: 661 SSSYHKREKNSE--SDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRS-YTRSRSLASSHS 717
Query: 451 DVRDHYIAAQVEQQHKQGQSQAASSSSVTS-------PIKMKIPIANTEKYMADKKEKSG 503
R + ++ SQ + SSS TS K ++ + + ++ KK S
Sbjct: 718 RSRSPSSRSHSRNKYSD-HSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSS 776
Query: 504 SLKLRIPIPPTDKSASKEELKMKIKVSSSERHS---SSDEGSGKSKHSSPHISRDHKEKH 560
S +K+ + +K + + S ++S SS + S S+ SS ++ +EK
Sbjct: 777 S----------EKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKE 826
Query: 561 KEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKR 620
K+ R H K+ S HS R+ SD + + S RK
Sbjct: 827 KQGQMERTHNKQEKNRGEEKSKSERECPHSKK-------RTLKENLSDHLRNGSKPKRKN 879
Query: 621 LHVN--DASHNHHSKMSKSSKSSGGLRTSQHP---RETGQEASGDQRS 663
+ D+ N ++K+SK+ HP +E G EA+ D S
Sbjct: 880 YAGSKWDSESNSERDVTKNSKN------DSHPSSDKEEG-EATSDSES 920
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 49.7 bits (117), Expect = 9e-06
Identities = 91/364 (25%), Positives = 124/364 (34%), Gaps = 61/364 (16%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG+ S H S + L G + G S +H + YS SGS
Sbjct: 1446 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYG----SGS 1501
Query: 376 QYNINFQQGPSISLHS-GLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKM 434
++ + S S HS GL HR + S SS ++ +G S HG +T G Q
Sbjct: 1502 GWSSSRGPYESGSSHSSGLGHRESR-SGQSSGYGQHGSSSGHSSTHGQHGSTSG---QSS 1557
Query: 435 SLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY 494
S ++ A Q GQ + SS S
Sbjct: 1558 SCGQH------------------GASSGQSSSHGQHGSGSSQS----------------- 1582
Query: 495 MADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE---GSGKSKHSSPH 551
+ GS + P S S++ S S R SSS + G G+S H
Sbjct: 1583 --SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 1640
Query: 552 -ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSAD-------GIPPTVLRSPV 603
S + +H S H+S + S SG SS G +H + G + R
Sbjct: 1641 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSS 1700
Query: 604 GLSSDGISSSSSSSRKRLHV---NDASHNHHSKMSKSSKSSGGLRT-SQHPRETGQEASG 659
G G S S SR R + +SH H S S S G + S H GQ SG
Sbjct: 1701 GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 1760
Query: 660 DQRS 663
S
Sbjct: 1761 SGHS 1764
Score = 48.1 bits (113), Expect = 3e-05
Identities = 90/364 (24%), Positives = 124/364 (34%), Gaps = 61/364 (16%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG+ S H S + L G + G S +H + Y + SGS
Sbjct: 976 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYR----SGS 1031
Query: 376 QYNINFQQGPSISLHS-GLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKM 434
++ + S S HS GL HR + S SS ++ +G S HG +T G Q
Sbjct: 1032 GWSSSRGPYESGSGHSSGLGHRESR-SGQSSGYGQHGSSSGHSSTHGQHGSTSG---QSS 1087
Query: 435 SLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY 494
S ++ A Q GQ + SS S
Sbjct: 1088 SCGQH------------------GASSGQSSSHGQHGSGSSQS----------------- 1112
Query: 495 MADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE---GSGKSKHSSPH 551
+ GS + P S S++ S S R SSS + G G+S H
Sbjct: 1113 --SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 1170
Query: 552 -ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSAD-------GIPPTVLRSPV 603
S + +H S H+S + S SG SS G +H + G + R
Sbjct: 1171 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 1230
Query: 604 GLSSDGISSSSSSSRKRLHV---NDASHNHHSKMSKSSKSSGGLRT-SQHPRETGQEASG 659
G G S S SR R + +SH H S S S G + S H GQ SG
Sbjct: 1231 GHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 1290
Query: 660 DQRS 663
S
Sbjct: 1291 SGHS 1294
Score = 47.0 bits (110), Expect = 6e-05
Identities = 90/364 (24%), Positives = 123/364 (33%), Gaps = 61/364 (16%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG+ S H S + L G + G S +H + YS SGS
Sbjct: 2386 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYG----SGS 2441
Query: 376 QYNINFQQGPSISLHS-GLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKM 434
++ + S S HS GL HR + S SS ++ +G S HG +T G Q
Sbjct: 2442 GWSSSRGPYESGSGHSSGLGHRESR-SGQSSGYGQHGSSSGHSSTHGQHGSTSG---QSS 2497
Query: 435 SLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY 494
S ++ A Q GQ + SS S
Sbjct: 2498 SCGQH------------------GASSGQSSSHGQHGSGSSQS----------------- 2522
Query: 495 MADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE---GSGKSKHSSPH 551
+ GS + P S S++ S S R SSS + G G+S H
Sbjct: 2523 --SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 2580
Query: 552 -ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSAD-------GIPPTVLRSPV 603
S + +H S H+S + S SG SS G +H + G + R
Sbjct: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 2640
Query: 604 GLSSDGISSSSSSSRKRLHV---NDASHNHHSKMSKSSKSSGGLRTS-QHPRETGQEASG 659
G G S S SR R + +SH H S S S G + H GQ SG
Sbjct: 2641 GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESG 2700
Query: 660 DQRS 663
S
Sbjct: 2701 SGHS 2704
Score = 45.1 bits (105), Expect = 2e-04
Identities = 43/150 (28%), Positives = 58/150 (38%), Gaps = 21/150 (14%)
Query: 530 SSSERHSSSDEGSGKSKHSSPHISRD-HKEKHKEHPSSRHHTSSHKHSHSHSGSSSG-GS 587
SS RH S+ SG+S S H S + +H S+ HH S S SG S G G
Sbjct: 839 SSQGRHGST---SGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQ 895
Query: 588 KHSADGIPPTVLRSPVGLS--------------SDGISSSSSSSRKRLHVNDASHNHHSK 633
+ S G P+ R G S G SSS + + S + HS
Sbjct: 896 RGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSS 955
Query: 634 MSKS--SKSSGGLRTSQHPRETGQEASGDQ 661
+ S+S R+ QH +G +S Q
Sbjct: 956 SYEQHGSRSGQSSRSEQHGSSSGSSSSYGQ 985
Score = 44.3 bits (103), Expect = 4e-04
Identities = 78/339 (23%), Positives = 116/339 (34%), Gaps = 31/339 (9%)
Query: 342 SYGLSSHQEWPQHQDSAR---TEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPD 398
S G S H H R + S + E S S + ++ Q S S S H R
Sbjct: 710 SSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQG 769
Query: 399 KISDHSSVKQEYTHKAGSSKHHGP------ISTTPGIIP----QKMSLDKYREKRKLETL 448
S HS + + +G S HG S++ G Q ++
Sbjct: 770 SGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYS 829
Query: 449 DLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLR 508
+ ++Q GQS ++ +S + + A + + GS +
Sbjct: 830 QHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQ 889
Query: 509 IPIPPTDKSASKEELKMKIKVSSSERHSSSDE---GSGKSKHSSPHISRDHKEKHKEHPS 565
P S S + S S R SSS GSG+S S + +H S
Sbjct: 890 SPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGS 949
Query: 566 SRHHTSSHKHSHSHSGSSSGGSKH-------SADGIPPTVLRSPVGLSSDGISSSSSSSR 618
H+SS++ S SG SS +H S+ G + R +G G S S S
Sbjct: 950 GSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1009
Query: 619 KRLHVNDASHNHHSKMSKS---SKSSGGLRTSQHPRETG 654
R H S S S +S G +S+ P E+G
Sbjct: 1010 SR-----GRHGSGSGQSSSYGPYRSGSGWSSSRGPYESG 1043
Score = 43.9 bits (102), Expect = 5e-04
Identities = 40/137 (29%), Positives = 52/137 (37%), Gaps = 13/137 (9%)
Query: 532 SERHSSSDEGSGKSKHSSPH-ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHS 590
S H GSG S H S H H +H S +SS H S SG +SG +H
Sbjct: 762 SSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHE 821
Query: 591 ADGIPPTVLRSPVGLSSDGISSSSSSSRKR----LHVNDASHNHHSKMSKSSKSSGGLRT 646
+ S G S G +S SS+ R + +S H S +SS
Sbjct: 822 SG--------SGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESA 873
Query: 647 SQHPRETGQEASGDQRS 663
S H G+ SG +S
Sbjct: 874 SHHASGRGRHGSGSGQS 890
Score = 43.5 bits (101), Expect = 6e-04
Identities = 84/356 (23%), Positives = 122/356 (34%), Gaps = 32/356 (8%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG S H S + G + G SS E +H S+ + Y Q SGS
Sbjct: 2113 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE--RHGSSSGSSSRYGQHG----SGS 2166
Query: 376 QYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPG---IIPQ 432
+ + + S S HS R S HSS ++ +G S GP + G + Q
Sbjct: 2167 RQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ 2226
Query: 433 KMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTE 492
S + + +Q + GQS ++ +
Sbjct: 2227 HESGSGHSSAYSQH----GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG 2282
Query: 493 KYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSS---DEGSGKSKHSS 549
+ + GS + P S S S S SSS GSG+S
Sbjct: 2283 SSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG 2342
Query: 550 PHISRDHKEK-HKEHPSSRHHTSSHKHSHSHSGSSSGGSKH-------SADGIPPTVLRS 601
H S + + +H S H+SS++ S SG SS G +H S+ G + R
Sbjct: 2343 HHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQ 2402
Query: 602 PVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSK---SSGGLRTSQHPRETG 654
+G G S S S R H S S S S G +S+ P E+G
Sbjct: 2403 SLGHGQHGSGSGQSPSPSR-----GRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG 2453
Score = 43.1 bits (100), Expect = 8e-04
Identities = 38/132 (28%), Positives = 56/132 (42%), Gaps = 15/132 (11%)
Query: 540 EGSGKSKHSSPHISRD----HKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIP 595
+GSG S+ S H+ H H +H S ++ S H S SG +SG +H +
Sbjct: 299 QGSG-SRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQ 357
Query: 596 PTVLRSPVGLSSDGISSSSSSSRKRLHVND---ASHNHHSKMSKSSKSSGGLRT-SQHPR 651
+ G S G S SSS+ + +S H S+ S S G + S+H
Sbjct: 358 SS------GYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSS 411
Query: 652 ETGQEASGDQRS 663
GQ +SG +S
Sbjct: 412 GRGQHSSGSGQS 423
Score = 42.0 bits (97), Expect = 0.002
Identities = 92/385 (23%), Positives = 137/385 (35%), Gaps = 85/385 (22%)
Query: 317 SGNISVQDSHTSDNLSMLATGM------PSTSYGLSSHQEWPQH-----QDSARTEQLYS 365
SG+ S Q H S + ++G S+SYG H+ +H Q S+ + Q
Sbjct: 368 SGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYG--QHESASRHSSGRGQHSSGSGQSPG 425
Query: 366 QKQETSLSGS-----QYNINF----QQGPSIS---LHSGLHHRPDKISDHSSVKQEYTHK 413
Q S SG Q+ F GP +S SG H + S+HSS ++
Sbjct: 426 HGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHH-ESSSEHSSGYTQHGSG 484
Query: 414 AGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAA 473
+G S HG + G Q + +QG S +
Sbjct: 485 SGHSSGHGQHGSRSG-------------------------------QSSRGERQGSSAGS 513
Query: 474 SSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSE 533
SSS + + + + + SGS + P +S S++ S
Sbjct: 514 SSSYGQHG-------SGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSG 566
Query: 534 RHSSS---DEGSGKSKHSSPHISRDHKEK-HKEHPSSRHHTSSHKHSHSHSGSSSGGSKH 589
R SS + GSG S SR + + +H SS H+S+H S SG SS +H
Sbjct: 567 RSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH 626
Query: 590 -------SADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVND----ASHNHHSKMSKSS 638
S+ G + G S S SR R H +D +S+ H S S
Sbjct: 627 GATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGR-HGSDFGHSSSYGQHGSGSGWS 685
Query: 639 KSSGGLRTSQHPRETGQEASGDQRS 663
S+G H +GQ + +S
Sbjct: 686 SSNG-----PHGSVSGQSSGFGHKS 705
Score = 40.4 bits (93), Expect = 0.005
Identities = 43/134 (32%), Positives = 52/134 (38%), Gaps = 16/134 (11%)
Query: 535 HSSS----DEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHS 590
HSSS GSG S + PH S + H S +S + S S SSG KH
Sbjct: 671 HSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHG 730
Query: 591 ADGIPPTVLRSPVGLSSDGISSS-----SSSSRKRLHVNDASHNHHSKMSKSSKSSGGLR 645
+ + RS SS G+SSS S S + H S + HS SS G
Sbjct: 731 SRSGQSS--RSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSG-- 786
Query: 646 TSQHPRETGQEASG 659
H GQ SG
Sbjct: 787 ---HSSSHGQHGSG 797
Score = 40.4 bits (93), Expect = 0.005
Identities = 41/141 (29%), Positives = 51/141 (36%), Gaps = 16/141 (11%)
Query: 532 SERHSSSDEGSGKSKHSSPHISR-DHKEKHKEHPSSRHHTSSHKHSHSHSG--------- 581
S H GSG+S P+ SR H +H S H+S++ S SG
Sbjct: 2665 SSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 2724
Query: 582 SSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDA-SHNHHSKMSKSSKS 640
S+SG S T S G G S SS R + SH H S S S
Sbjct: 2725 STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSS 2784
Query: 641 SGGLRTSQHPRETGQEASGDQ 661
G QH +GQ + Q
Sbjct: 2785 YG-----QHGSGSGQSSGYSQ 2800
Score = 39.3 bits (90), Expect = 0.012
Identities = 47/141 (33%), Positives = 58/141 (41%), Gaps = 26/141 (18%)
Query: 527 IKVSSSERHSSS--DEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSS 584
++ S HSSS GSG SS SR H E S TS S SG SS
Sbjct: 310 VRHGSGSGHSSSHGQHGSG----SSYSYSRGHYE------SGSGQTSGFGQHESGSGQSS 359
Query: 585 GGSKHSADGIPPTVLRSPVGLSSDGISSS---SSSSRKRLHVNDASHNHHSKMSKSSKSS 641
G SKH + G + + G +S SSS SSSR+ +S+ H S+ S
Sbjct: 360 GYSKHGS-GSGHSSSQGQHGSTSGQASSSGQHGSSSRQ-----SSSYGQHESASRHSSGR 413
Query: 642 GGLRTSQHPRETGQEASGDQR 662
G QH +GQ QR
Sbjct: 414 G-----QHSSGSGQSPGHGQR 429
Score = 39.3 bits (90), Expect = 0.012
Identities = 45/138 (32%), Positives = 52/138 (37%), Gaps = 20/138 (14%)
Query: 534 RHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADG 593
RH S S S P + H H SS +SS+ S SG SSG +H
Sbjct: 2083 RHGSGSGRSSSSGQHGPGLGESSGFGH--HESSSGQSSSYSQHGSGSGHSSGYGQHG--- 2137
Query: 594 IPPTVLRSPVGLSSDGI---SSSSSSSRKRLHVN----DASHNHHSKMSKSSKSSGGLRT 646
S G SS G SSS SSSR H + + H S S S G +
Sbjct: 2138 -------SRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS 2190
Query: 647 -SQHPRETGQEASGDQRS 663
S H GQ SG RS
Sbjct: 2191 GSGHSSSHGQHGSGSGRS 2208
Score = 37.7 bits (86), Expect = 0.034
Identities = 85/368 (23%), Positives = 129/368 (35%), Gaps = 56/368 (15%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG S H S + G + G SS E +H+ S+ + Y Q SGS
Sbjct: 237 SSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGE--RHRSSSGSSSSYGQHG----SGS 290
Query: 376 QYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS 435
+ ++ + S S S H R S HSS ++ + S G + G Q
Sbjct: 291 RQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSG---QTSG 347
Query: 436 LDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYM 495
++ + + + QH QA+SS S + E
Sbjct: 348 FGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHE--- 404
Query: 496 ADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE---GSGKSKHSSPHI 552
+ + SG + S S + + S S + SS + G G+S S P++
Sbjct: 405 SASRHSSGRGQ--------HSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYV 456
Query: 553 S--------------RDHKEKHKEHPSSRHHTSSHKHSHSHSG---------SSSGGSKH 589
S +H + +H S H+S H S SG SS+G S
Sbjct: 457 SGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSS-- 514
Query: 590 SADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSG---GLRT 646
S+ G + R +G S G S S S R H S+ S S G G +
Sbjct: 515 SSYGQHGSGSRQSLGHSRHGSGSGQSPSPSR-----GRHESGSRQSSSYGPHGYGSGRSS 569
Query: 647 SQHPRETG 654
S+ P E+G
Sbjct: 570 SRGPYESG 577
Score = 37.7 bits (86), Expect = 0.034
Identities = 41/156 (26%), Positives = 55/156 (35%), Gaps = 26/156 (16%)
Query: 532 SERHSSSDEGSGKSKHSSPHISRDHKEKHK----------EHPSSRHHTSSHKHSHSHSG 581
S+ S S SG KH S E+H +H S H +S H S SG
Sbjct: 714 SQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSG 773
Query: 582 ---------SSSGGSKHSADGIPPTVLRSPVGLSSDGISSSS------SSSRKRLHVNDA 626
SSSG S T S G G +S S S + + +
Sbjct: 774 HSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGS 833
Query: 627 SHNHHSKMSKSSKSSGGLRTS-QHPRETGQEASGDQ 661
+ H S + +SG +S QH +GQ +S Q
Sbjct: 834 ASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQ 869
Score = 37.4 bits (85), Expect = 0.045
Identities = 36/126 (28%), Positives = 50/126 (39%), Gaps = 17/126 (13%)
Query: 536 SSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIP 595
SSS + SG ++H S H +++H S +S + S SGSSS +H +
Sbjct: 1406 SSSWQSSGCTQHGS---GSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGS-- 1460
Query: 596 PTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSK---SSGGLRTSQHPRE 652
R +G G S S S R H S S S S G +S+ P E
Sbjct: 1461 ----RQSLGHGQHGSGSGQSPSPSR-----GRHGSGSGQSSSYSPYGSGSGWSSSRGPYE 1511
Query: 653 TGQEAS 658
+G S
Sbjct: 1512 SGSSHS 1517
Score = 37.0 bits (84), Expect = 0.058
Identities = 37/140 (26%), Positives = 47/140 (33%), Gaps = 26/140 (18%)
Query: 530 SSSERHSSSDEGSGK-------SKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGS 582
S ERH SS S + S+ SS H + H S H SH GS
Sbjct: 2144 SRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGS 2203
Query: 583 SSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSG 642
SG S SS G S S +++ H S S+ SG
Sbjct: 2204 GSGRS------------------SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG 2245
Query: 643 GL-RTSQHPRETGQEASGDQ 661
QH +GQ ++ DQ
Sbjct: 2246 HFCSQGQHGSTSGQSSTFDQ 2265
Score = 36.6 bits (83), Expect = 0.076
Identities = 84/357 (23%), Positives = 128/357 (35%), Gaps = 33/357 (9%)
Query: 317 SGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQ 376
SG+ S H S + + G ++ G SS + Q+ + T Q S Q S GS
Sbjct: 1761 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD----QEGSSTGQSSSHGQHGS--GSS 1814
Query: 377 YNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAG----SSKHHGPISTTPGIIPQ 432
+ ++ Q S S S R S HSS ++ +G S +H + G
Sbjct: 1815 QSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1874
Query: 433 KMSL---DKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIA 489
+ S Y + H + + +Q S + SSSS +
Sbjct: 1875 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHG------S 1928
Query: 490 NTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSS---DEGSGKSK 546
+ + + + SGS + P S S + S S SS + GSG S
Sbjct: 1929 GSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSS 1988
Query: 547 HSSPHISRDHKEK-HKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGL 605
SR + + +H SS H+S+H S SG SS +H A + S G
Sbjct: 1989 GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGAS----SGQSSSHGQ 2044
Query: 606 SSDGISSSSSSSRKRLHVNDA-SHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQ 661
G S SS R+ + H S+ S S G +H +G+ +S Q
Sbjct: 2045 HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG-----RHGSGSGRSSSSGQ 2096
Score = 35.8 bits (81), Expect = 0.13
Identities = 40/138 (28%), Positives = 47/138 (34%), Gaps = 21/138 (15%)
Query: 532 SERHSSSDEGSGKSKHSSPHISRD-HKEKHKEHPSSRHHTSSHKHSHSHSG--------- 581
S H GSG+S P+ SR H +H S H+S++ S SG
Sbjct: 1255 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 1314
Query: 582 SSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSS 641
S+SG S T S G G S SS R H S S S
Sbjct: 1315 STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGR---------HGAGSGQSPSRGRH 1365
Query: 642 GGLRTSQHPRETGQEASG 659
G S H GQ SG
Sbjct: 1366 GS--GSGHSSSYGQHGSG 1381
Score = 35.8 bits (81), Expect = 0.13
Identities = 42/141 (29%), Positives = 53/141 (37%), Gaps = 15/141 (10%)
Query: 530 SSSERHSSSDEGSGK-------SKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGS 582
S ERH SS S + S+ SS H + + PS H S HS SH
Sbjct: 1674 SRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSG--QSPSRGRHGSGLGHSSSHGQH 1731
Query: 583 SSGGSKHSADGIPPTVLRSPVGLSS-DGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSS 641
SG + S+ G P RS G SS G S S + + H + +S
Sbjct: 1732 GSGSGRSSSRG--PYESRS--GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 1787
Query: 642 GGLRT-SQHPRETGQEASGDQ 661
G T Q TGQ +S Q
Sbjct: 1788 GQSSTFDQEGSSTGQSSSHGQ 1808
Score = 35.4 bits (80), Expect = 0.17
Identities = 45/147 (30%), Positives = 54/147 (36%), Gaps = 25/147 (17%)
Query: 530 SSSERHSSSD--------EGSGKSKHSSPH----ISRDHKEKHKEHPSSRHHTSSHKHSH 577
S ERH SS GSG S+ SS H H H S H+SSH
Sbjct: 1204 SRGERHGSSSGSSSHYGQHGSG-SRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHG 1262
Query: 578 SHSG-SSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSK 636
S SG SSS G S G S G G SS+ S+ + + H +
Sbjct: 1263 SGSGRSSSRGPYESRSG-----HSSVFGQHESGSGHSSAYSQ-----HGSGSGHFCSQGQ 1312
Query: 637 SSKSSGGLRT-SQHPRETGQEASGDQR 662
+SG T Q TGQ +S R
Sbjct: 1313 HGSTSGQSSTFDQEGSSTGQSSSYGHR 1339
Score = 35.4 bits (80), Expect = 0.17
Identities = 39/138 (28%), Positives = 51/138 (36%), Gaps = 16/138 (11%)
Query: 532 SERHSSSDEGSGKSKHSSPHISRD-HKEKHKEHPSSRHHTSSHKHSHSHSG--------- 581
S H GSG+S P+ SR H +H S H+S++ S SG
Sbjct: 1725 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 1784
Query: 582 SSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDA-SHNHHSKMSKSSKS 640
S+SG S T S G G S SSS ++ + S H S S S
Sbjct: 1785 STSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSS 1844
Query: 641 SGGLRTSQHPRETGQEAS 658
G QH +G +S
Sbjct: 1845 YG-----QHGSGSGWSSS 1857
Score = 35.4 bits (80), Expect = 0.17
Identities = 39/138 (28%), Positives = 51/138 (36%), Gaps = 16/138 (11%)
Query: 532 SERHSSSDEGSGKSKHSSPHISRD-HKEKHKEHPSSRHHTSSHKHSHSHSG--------- 581
S H GSG+S P+ SR H +H S H+S++ S SG
Sbjct: 2195 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 2254
Query: 582 SSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDA-SHNHHSKMSKSSKS 640
S+SG S T S G G S SSS ++ + S H S S S
Sbjct: 2255 STSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSS 2314
Query: 641 SGGLRTSQHPRETGQEAS 658
G QH +G +S
Sbjct: 2315 YG-----QHGSGSGWSSS 2327
Score = 34.3 bits (77), Expect = 0.38
Identities = 39/135 (28%), Positives = 51/135 (37%), Gaps = 14/135 (10%)
Query: 530 SSSERHSSSDEGSGKSKHSSPHIS-RDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSK 588
SS H S GSG+S S H S H +++H S +S + S SG SS +
Sbjct: 698 SSGFGHKS---GSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQ 754
Query: 589 HSADGIPPTVLRSPVGLSSDGISSSSSSSRKR---LHVNDASHNHHSKMSKSSKSSGGLR 645
H + G G S S SR R + +SH H + S S G
Sbjct: 755 HGSGS------HQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYE 808
Query: 646 T-SQHPRETGQEASG 659
+ S GQ SG
Sbjct: 809 SGSGQASGFGQHESG 823
Score = 33.9 bits (76), Expect = 0.49
Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 3/85 (3%)
Query: 530 SSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKH 589
S R S S + SG +H + H H S +SS+ S SG SSG S+H
Sbjct: 2745 SYGHRGSGSSQSSGYGRHGA---GSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQH 2801
Query: 590 SADGIPPTVLRSPVGLSSDGISSSS 614
+ G + DG SS S
Sbjct: 2802 GSGSGQDGYSYCKGGSNHDGGSSGS 2826
Score = 33.5 bits (75), Expect = 0.64
Identities = 43/150 (28%), Positives = 58/150 (38%), Gaps = 23/150 (15%)
Query: 530 SSSERHSS-SDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSG--- 585
SS++ H S S + SG S+H S S + +H S S H + GS SG
Sbjct: 216 SSNDTHGSGSGQSSGFSQHKS---SSGQSSGYSQHGSG----SGHSSGYGQHGSRSGQSS 268
Query: 586 -GSKH-------SADGIPPTVLRSPVGLSSDGISSSSSSSRKRL---HVNDASHNHHSKM 634
G +H S+ G + R +G G S S S R + +SH H
Sbjct: 269 RGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSG 328
Query: 635 SKSSKSSGGLRT-SQHPRETGQEASGDQRS 663
S S S G + S GQ SG +S
Sbjct: 329 SSYSYSRGHYESGSGQTSGFGQHESGSGQS 358
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 47.4 bits (111), Expect = 4e-05
Identities = 74/344 (21%), Positives = 116/344 (33%), Gaps = 26/344 (7%)
Query: 317 SGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQ 376
+GN D+ SD+ + S S S+ + DS ++ S ++S S S
Sbjct: 529 NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS 588
Query: 377 YNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSL 436
+ + S S +S SD S K+ SSK S +
Sbjct: 589 DSSDSDS--SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS-------- 638
Query: 437 DKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMA 496
K ++ D + D + S +S SS +S +N+ +
Sbjct: 639 -------KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD-SS 690
Query: 497 DKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH 556
D + S S + +D +S S S +SSD S S SS +
Sbjct: 691 DSSDSSNSSESSDSSDSSDSDSSDS--------SDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Query: 557 KEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSS 616
+ +S + S S+S S S S S+D + S SS+SS
Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802
Query: 617 SRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGD 660
S +D+S + S S SS SS +S + S D
Sbjct: 803 SSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD 846
Score = 45.4 bits (106), Expect = 2e-04
Identities = 72/348 (20%), Positives = 111/348 (31%), Gaps = 11/348 (3%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+S + DS S N S + S++ SS DS+ + + S S
Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS 997
Query: 376 QYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS 435
+ N S S + D + S + + S S + S
Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057
Query: 436 LDKYREKRKLETLDL-DVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY 494
D ++ D D D +++ S +S SS +S ++
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD-------SSDSSD 1110
Query: 495 MADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSD--EGSGKSKHSSPHI 552
+D + S S +D S S + SSE SSD + S S S
Sbjct: 1111 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170
Query: 553 SRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISS 612
S D + SS SS S S S S S S+D + S SS
Sbjct: 1171 SSDSSDSSNSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229
Query: 613 SSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGD 660
S+ S +D+S + +S S S S + + Q SG+
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/349 (22%), Positives = 120/349 (34%), Gaps = 26/349 (7%)
Query: 318 GNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQY 377
G DS +SD+ + + S S S+ DS ++ S ++ S S
Sbjct: 545 GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS----SDSDSSDSDSSDSSDSDSSDSSN 600
Query: 378 NINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLD 437
+ + S S D SD S K E SK S + S D
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSS--KSESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658
Query: 438 KYREKRKLETLDL-DVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMA 496
++ D D D ++ S +S+SS +S +++ +
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD--------SSDSSDS 710
Query: 497 DKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH 556
D + S S + S+ + S S S+S + S S S+ S D
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Query: 557 KEKHKEHPSSRHHTS--SHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSS 614
+ SS S S S S S+S S +S+D S SSD SS+S
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS-------SDSSDSSDSDSSNS 823
Query: 615 SSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQRS 663
S S +D+S++ S S SS SS G + R +S S
Sbjct: 824 SDSSNSSDSSDSSNS--SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDS 870
Score = 44.3 bits (103), Expect = 4e-04
Identities = 66/344 (19%), Positives = 114/344 (33%), Gaps = 5/344 (1%)
Query: 321 SVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNIN 380
S S +SD+ + + S S S + DS+ + ++ S S + N
Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799
Query: 381 FQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYR 440
+ S S D S +SS + + SS S + D
Sbjct: 800 SSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS----SDSSDSSDSSDGSDSDS 855
Query: 441 EKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY-MADKK 499
R + D D ++ S +S+SS +S +++ +D
Sbjct: 856 SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915
Query: 500 EKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEK 559
+ S S +D S S + SS+ +SSD + +S S +
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975
Query: 560 HKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRK 619
+ +S + S S S S S S S+D + + S+ SS+SS S
Sbjct: 976 SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 1035
Query: 620 RLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQRS 663
+D+S + S S S +S S ++ + S
Sbjct: 1036 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079
Score = 42.0 bits (97), Expect = 0.002
Identities = 73/376 (19%), Positives = 116/376 (30%), Gaps = 9/376 (2%)
Query: 290 DSVTGVPTNPSFQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQ 349
DS G ++ S + S+++ + +S N S + N S ++ +S S
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905
Query: 350 EWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQE 409
+ + S E+S S N + S S S S+ S
Sbjct: 906 SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS 965
Query: 410 YTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDL-DVRDHYIAAQVEQQHKQG 468
+S S + S D + D D D ++
Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025
Query: 469 QSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIK 528
S +S SS +S ++ +D + S S +D S S +
Sbjct: 1026 DSSNSSDSSDSSD-------SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078
Query: 529 VSSSERHSSSDEG-SGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGS 587
SSE SSD S S SS + S ++S S S S S S
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138
Query: 588 KHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTS 647
+S+D + S SS SS S +D+S++ S S S S S
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Query: 648 QHPRETGQEASGDQRS 663
++ + S
Sbjct: 1199 SDSSDSSDSSDSSDSS 1214
Score = 40.4 bits (93), Expect = 0.005
Identities = 70/346 (20%), Positives = 112/346 (32%), Gaps = 15/346 (4%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+S + + DS+ S N S + S S S+ + DS+ ++ S S S
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDS--SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 376 QYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS 435
+ + S G SD S+ S+ S+ S
Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD-----SNES 888
Query: 436 LDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYM 495
+ + D D D ++ S +S+SS S ++
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN-------SSDSSNS 941
Query: 496 ADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRD 555
+D + S S +D S S + SS +SS S S SS
Sbjct: 942 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001
Query: 556 HKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSS 615
+ + S ++S S+S S+S S S+D + S SS SS
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 616 SSRKRLHVNDASHNHHSK-MSKSSKSSGGLRTSQHPRETGQEASGD 660
S +D+S + S S+SS SS +S + S D
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107
Score = 40.4 bits (93), Expect = 0.005
Identities = 71/350 (20%), Positives = 108/350 (30%), Gaps = 3/350 (0%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+S N S DS S N S + S+ SS+ + + S ++S S
Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955
Query: 376 QYNINFQQGPSISLHSGLHHRPDKI-SDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKM 434
N + S S S D S SS + + + SS ++
Sbjct: 956 SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015
Query: 435 SLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY 494
S + D D ++ S +S+SS +S +++
Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD- 1074
Query: 495 MADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEG-SGKSKHSSPHIS 553
+D + S S +D S S + SS+ SSD S S SS
Sbjct: 1075 SSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134
Query: 554 RDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSS 613
+ S + S S S S S S S+D + S SS
Sbjct: 1135 SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194
Query: 614 SSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQRS 663
SS S +D+S + S S S S S E+ + S
Sbjct: 1195 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS 1244
Score = 38.5 bits (88), Expect = 0.020
Identities = 66/348 (18%), Positives = 110/348 (31%), Gaps = 4/348 (1%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+S + D SD+ + + S S S DS+ + + S ++S S +
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES-SNSSDSSDSSN 899
Query: 376 QYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS 435
+ + + S S + D +S + + +S S + S
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959
Query: 436 LDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYM 495
D ++ D D ++ S +S SS +S +++
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN-S 1018
Query: 496 ADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRD 555
+D S S +D S S + SS SSD S S SS
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD--SSDSSDSSDSSDSS 1076
Query: 556 HKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSS 615
E S ++S S S S S S S+D + + S SS SS
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136
Query: 616 SSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQRS 663
S +D+S + S S S S S ++ ++ S
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184
Score = 36.6 bits (83), Expect = 0.076
Identities = 37/136 (27%), Positives = 51/136 (37%), Gaps = 7/136 (5%)
Query: 530 SSSERHSSSDEGSGKSKHSSPHISRDHKEKH--KEHPSSRHHTSSHKHSHSHSGSSSGGS 587
S+S+ ++S G+G + + S K K + SS SS S S SS S
Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS 576
Query: 588 KHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTS 647
+D S SSD +SS SS +D+S + S S SKS S
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS-----SDSSDSSDSSDSSDSKSDSSKSES 631
Query: 648 QHPRETGQEASGDQRS 663
+ S D S
Sbjct: 632 DSSDSDSKSDSSDSNS 647
Score = 34.7 bits (78), Expect = 0.29
Identities = 67/343 (19%), Positives = 105/343 (30%), Gaps = 19/343 (5%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+S + S +SD+ + + S S S + DS+ + + S S
Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024
Query: 376 QYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS 435
+ N S S D S + + S S + S
Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSES 1084
Query: 436 LDKYREKRKLETLDL-DVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY 494
D ++ D D D ++ S +S SS +S +N+
Sbjct: 1085 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD- 1143
Query: 495 MADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEG----------SGK 544
+D E S S +D S S + +SS+ SSD S
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203
Query: 545 SKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVG 604
S SS + S + S++ S S S S S +S+D S
Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDS-------SDSS 1256
Query: 605 LSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTS 647
SSD S S+ S + + ++N S S S TS
Sbjct: 1257 DSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299
>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 2 [Homo sapiens]
Length = 754
Score = 47.4 bits (111), Expect = 4e-05
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 17/107 (15%)
Query: 551 HISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGI 610
H++ H H +S HH H H H H G + G++ P V SP
Sbjct: 581 HVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNR-----TRPRVYNSP-------- 627
Query: 611 SSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEA 657
++SSS++ + V H+HHS S SS ++ +S G +A
Sbjct: 628 -TNSSSTQDSMEV---GHSHHSMTSLSSSTTSSSTSSSSTGNQGNQA 670
>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 1 [Homo sapiens]
Length = 763
Score = 47.4 bits (111), Expect = 4e-05
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 17/107 (15%)
Query: 551 HISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGI 610
H++ H H +S HH H H H H G + G++ P V SP
Sbjct: 590 HVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNR-----TRPRVYNSP-------- 636
Query: 611 SSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEA 657
++SSS++ + V H+HHS S SS ++ +S G +A
Sbjct: 637 -TNSSSTQDSMEV---GHSHHSMTSLSSSTTSSSTSSSSTGNQGNQA 679
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 46.6 bits (109), Expect = 7e-05
Identities = 38/122 (31%), Positives = 50/122 (40%), Gaps = 4/122 (3%)
Query: 531 SSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHS 590
S +R S D S S S H R H ++ SS+H + HK+S S S S+
Sbjct: 884 SRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSR 943
Query: 591 ADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHP 650
+ T RS S G S SSS SR R S HS S S R+++ P
Sbjct: 944 SRSRSHTRERS----RSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSP 999
Query: 651 RE 652
+
Sbjct: 1000 SQ 1001
Score = 45.4 bits (106), Expect = 2e-04
Identities = 49/225 (21%), Positives = 81/225 (36%), Gaps = 19/225 (8%)
Query: 438 KYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMAD 497
++++K+K + R H A E++ + +S S K A +
Sbjct: 674 RHKKKKKHKKSSKHKRKH--KADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGP 731
Query: 498 KKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHK 557
K E GS P PP + ++++ + + + DEG G S S H R HK
Sbjct: 732 KPEPPGSGS---PAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSS-SQDHGGRKHK 787
Query: 558 EKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSS 617
+ R + SH S G + S D SS + S S
Sbjct: 788 GELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDA------------SSHRLHQKSPSQ 835
Query: 618 RKRLHVNDASHNHHSK-MSKSSKSSGGLRTSQHPRETGQEASGDQ 661
+ S + HS+ S+S + R+S+ + +AS DQ
Sbjct: 836 YSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQ 880
Score = 35.0 bits (79), Expect = 0.22
Identities = 78/343 (22%), Positives = 104/343 (30%), Gaps = 72/343 (20%)
Query: 367 KQETSLS-GSQYNINFQQGPSISLHSGLHHRPDKISDHS-SVKQEYTHKAGS-------- 416
KQE S GS+ + PS SG HR K H S K + HKA +
Sbjct: 644 KQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAE 703
Query: 417 ---------------SKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQV 461
+K P + G P+ R+ D + + A+
Sbjct: 704 SGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEE 763
Query: 462 EQQHKQGQSQAASSSSVTSPIKMK--IPIANTEKYMADKKEKSGSLKLRIPIPPTDKS-A 518
K+ + SSS K K +P ++ ++ K+ S + + D A
Sbjct: 764 GSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDA 823
Query: 519 SKEELKMKIKVSSSERHSSSDEGSGKSK--------HSSPHISR---------------- 554
S L K SE D GS S+ HSS SR
Sbjct: 824 SSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCY 883
Query: 555 -------DHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSS 607
D S RH SH S SS SK R S
Sbjct: 884 SRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSK-----------RHKYSSSD 932
Query: 608 D--GISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQ 648
D +S S S SR R H + S + S S S R S+
Sbjct: 933 DDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSR 975
Score = 29.6 bits (65), Expect = 9.3
Identities = 45/191 (23%), Positives = 62/191 (32%), Gaps = 27/191 (14%)
Query: 499 KEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKS---KHSSPHISRD 555
KE G +R D AS K H S E +G+S K S
Sbjct: 615 KEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHR 674
Query: 556 HKEKHKEHPSSRHH-----TSSHKHSHSHSGSSS-----GGSKHSADGIPPTVLRSPVGL 605
HK+K K SS+H + K S + SG S K + P R P
Sbjct: 675 HKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKP- 733
Query: 606 SSDGISSSSSSSRKRLHVNDASHN----HHSKMSKSSKSSGGLRTSQH---------PRE 652
G S + R+R +D+ K + GG + H P
Sbjct: 734 EPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPS 793
Query: 653 TGQEASGDQRS 663
+ Q +G +RS
Sbjct: 794 SCQRRAGTKRS 804
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 46.2 bits (108), Expect = 1e-04
Identities = 54/217 (24%), Positives = 85/217 (39%), Gaps = 37/217 (17%)
Query: 463 QQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEE 522
++H +G+ + + P K EK A K E+ +PP+ K +
Sbjct: 961 RRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPER---------LPPSMKG----K 1007
Query: 523 LKMKIKVSSSERHSSSDE----GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHS 578
+K K +SSS+ S D+ G ++S+ + D E+ K+ SS S + +
Sbjct: 1008 IKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSE---SDSDENQN 1064
Query: 579 HSGSSSGG--------SKHSADGIPPTVLRSPVGL-SSDGISSSSSSSRKRLHVND---- 625
SGS +G S +D P+ R P G SD S S S + ND
Sbjct: 1065 KSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPA 1124
Query: 626 ---ASHNHHSKMSKSSKSSG-GLRTSQHPRETGQEAS 658
A +H S+ ++ SG G P + EAS
Sbjct: 1125 SPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEAS 1161
>gi|113415504 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 1/124 (0%)
Query: 516 KSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKH 575
KS+++ K K S E+ + G +K SS R + K H +S +S+
Sbjct: 20 KSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEK-DRGRDKTRKRHSASSGSSSTRSR 78
Query: 576 SHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMS 635
S S S S S S S+ G + S G SS SSSSSSS + H++ +
Sbjct: 79 SSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSR 138
Query: 636 KSSK 639
SK
Sbjct: 139 SKSK 142
Score = 40.4 bits (93), Expect = 0.005
Identities = 44/163 (26%), Positives = 61/163 (37%), Gaps = 10/163 (6%)
Query: 492 EKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPH 551
+K + KE + R P P K S E+ K + K + + SS ++ G+ K H
Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESS-EKDRGRDKTRKRH 66
Query: 552 ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSG-GSKHSADGIPPTVLRSPVGLSSDGI 610
+ + SS + S + S SGSSS S S S SS
Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSS-------STSRSSSSSS 119
Query: 611 SSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRET 653
SS S S +R H N SK K + R S P+ T
Sbjct: 120 SSGSPSPSRRRHDNRRRSRSKSKPPKRDEKE-RKRRSPSPKPT 161
Score = 31.6 bits (70), Expect = 2.5
Identities = 37/149 (24%), Positives = 55/149 (36%), Gaps = 21/149 (14%)
Query: 515 DKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH-KEKHKEHPSSRHHTSSH 573
D S K++ + +K ++++ S+ K K S S+D K+K SS
Sbjct: 2 DLSGVKKKSLLGVK-ENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 574 KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
K HS SS S S SSS+SSS +S + S
Sbjct: 61 KTRKRHSASSGSSSTRSR-------------------SSSTSSSGSSTSTGSSSGSSSSS 101
Query: 634 MSKSSKSSGGLRTSQHPRETGQEASGDQR 662
S S SS R+S +G + +R
Sbjct: 102 ASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
>gi|169166499 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 1/124 (0%)
Query: 516 KSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKH 575
KS+++ K K S E+ + G +K SS R + K H +S +S+
Sbjct: 20 KSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEK-DRGRDKTRKRHSASSGSSSTRSR 78
Query: 576 SHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMS 635
S S S S S S S+ G + S G SS SSSSSSS + H++ +
Sbjct: 79 SSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSR 138
Query: 636 KSSK 639
SK
Sbjct: 139 SKSK 142
Score = 40.4 bits (93), Expect = 0.005
Identities = 44/163 (26%), Positives = 61/163 (37%), Gaps = 10/163 (6%)
Query: 492 EKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPH 551
+K + KE + R P P K S E+ K + K + + SS ++ G+ K H
Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESS-EKDRGRDKTRKRH 66
Query: 552 ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSG-GSKHSADGIPPTVLRSPVGLSSDGI 610
+ + SS + S + S SGSSS S S S SS
Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSS-------STSRSSSSSS 119
Query: 611 SSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRET 653
SS S S +R H N SK K + R S P+ T
Sbjct: 120 SSGSPSPSRRRHDNRRRSRSKSKPPKRDEKE-RKRRSPSPKPT 161
Score = 31.6 bits (70), Expect = 2.5
Identities = 37/149 (24%), Positives = 55/149 (36%), Gaps = 21/149 (14%)
Query: 515 DKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH-KEKHKEHPSSRHHTSSH 573
D S K++ + +K ++++ S+ K K S S+D K+K SS
Sbjct: 2 DLSGVKKKSLLGVK-ENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 574 KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
K HS SS S S SSS+SSS +S + S
Sbjct: 61 KTRKRHSASSGSSSTRSR-------------------SSSTSSSGSSTSTGSSSGSSSSS 101
Query: 634 MSKSSKSSGGLRTSQHPRETGQEASGDQR 662
S S SS R+S +G + +R
Sbjct: 102 ASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
>gi|113415498 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 1/124 (0%)
Query: 516 KSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKH 575
KS+++ K K S E+ + G +K SS R + K H +S +S+
Sbjct: 20 KSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEK-DRGRDKTRKRHSASSGSSSTRSR 78
Query: 576 SHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMS 635
S S S S S S S+ G + S G SS SSSSSSS + H++ +
Sbjct: 79 SSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSR 138
Query: 636 KSSK 639
SK
Sbjct: 139 SKSK 142
Score = 40.4 bits (93), Expect = 0.005
Identities = 44/163 (26%), Positives = 61/163 (37%), Gaps = 10/163 (6%)
Query: 492 EKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPH 551
+K + KE + R P P K S E+ K + K + + SS ++ G+ K H
Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESS-EKDRGRDKTRKRH 66
Query: 552 ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSG-GSKHSADGIPPTVLRSPVGLSSDGI 610
+ + SS + S + S SGSSS S S S SS
Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSS-------STSRSSSSSS 119
Query: 611 SSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRET 653
SS S S +R H N SK K + R S P+ T
Sbjct: 120 SSGSPSPSRRRHDNRRRSRSKSKPPKRDEKE-RKRRSPSPKPT 161
Score = 31.6 bits (70), Expect = 2.5
Identities = 37/149 (24%), Positives = 55/149 (36%), Gaps = 21/149 (14%)
Query: 515 DKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH-KEKHKEHPSSRHHTSSH 573
D S K++ + +K ++++ S+ K K S S+D K+K SS
Sbjct: 2 DLSGVKKKSLLGVK-ENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 574 KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
K HS SS S S SSS+SSS +S + S
Sbjct: 61 KTRKRHSASSGSSSTRSR-------------------SSSTSSSGSSTSTGSSSGSSSSS 101
Query: 634 MSKSSKSSGGLRTSQHPRETGQEASGDQR 662
S S SS R+S +G + +R
Sbjct: 102 ASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
>gi|88973230 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 3 [Homo sapiens]
Length = 305
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 1/124 (0%)
Query: 516 KSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKH 575
KS+++ K K S E+ + G +K SS R + K H +S +S+
Sbjct: 20 KSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEK-DRGRDKTRKRHSASSGSSSTRSR 78
Query: 576 SHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMS 635
S S S S S S S+ G + S G SS SSSSSSS + H++ +
Sbjct: 79 SSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSR 138
Query: 636 KSSK 639
SK
Sbjct: 139 SKSK 142
Score = 40.4 bits (93), Expect = 0.005
Identities = 44/163 (26%), Positives = 61/163 (37%), Gaps = 10/163 (6%)
Query: 492 EKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPH 551
+K + KE + R P P K S E+ K + K + + SS ++ G+ K H
Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESS-EKDRGRDKTRKRH 66
Query: 552 ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSG-GSKHSADGIPPTVLRSPVGLSSDGI 610
+ + SS + S + S SGSSS S S S SS
Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSS-------STSRSSSSSS 119
Query: 611 SSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRET 653
SS S S +R H N SK K + R S P+ T
Sbjct: 120 SSGSPSPSRRRHDNRRRSRSKSKPPKRDEKE-RKRRSPSPKPT 161
Score = 31.6 bits (70), Expect = 2.5
Identities = 37/149 (24%), Positives = 55/149 (36%), Gaps = 21/149 (14%)
Query: 515 DKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH-KEKHKEHPSSRHHTSSH 573
D S K++ + +K ++++ S+ K K S S+D K+K SS
Sbjct: 2 DLSGVKKKSLLGVK-ENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 574 KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
K HS SS S S SSS+SSS +S + S
Sbjct: 61 KTRKRHSASSGSSSTRSR-------------------SSSTSSSGSSTSTGSSSGSSSSS 101
Query: 634 MSKSSKSSGGLRTSQHPRETGQEASGDQR 662
S S SS R+S +G + +R
Sbjct: 102 ASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
>gi|61676093 cyclin C isoform b [Homo sapiens]
Length = 198
Score = 45.8 bits (107), Expect = 1e-04
Identities = 38/176 (21%), Positives = 76/176 (43%), Gaps = 26/176 (14%)
Query: 82 ISSTALFLAAKVEEQA--------RKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELV 133
++ T +FLA+KVEE V+K + P E + + ++
Sbjct: 1 MAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKE---------FPYRMNHIL 51
Query: 134 ILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPT 193
E +L+ + + + HP+ +++ Q + +D+ + N + T CL Y P
Sbjct: 52 ECEFYLLELMDCCLIVYHPYRPLLQYVQDM-GQEDMLLPLAWRIVNDTYRTDLCLLYPPF 110
Query: 194 VIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPN 249
+IA C+H+AC + D + W + + +V +E + E+ L++ E+ N
Sbjct: 111 MIALACLHVAC------VVQQKDARQW--FAELSVDMEKILEIIRVILKLYEQWKN 158
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 45.4 bits (106), Expect = 2e-04
Identities = 53/231 (22%), Positives = 85/231 (36%), Gaps = 45/231 (19%)
Query: 436 LDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYM 495
LD+ +K+K + D + + ++HK S ++SSSS +S TE
Sbjct: 228 LDRLEKKKKKK--DRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSS----------TETSE 275
Query: 496 ADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRD 555
+ + +S + + +I K+ K K ++ D+ + H S
Sbjct: 276 SSSESESNNKEKKI--------QRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHH 327
Query: 556 HKEKHKEHPSSRHHTSSH---KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISS 612
++EK KE P H SS K SHS S S KHS + G
Sbjct: 328 NREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPE--------------KRGSER 373
Query: 613 SSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQRS 663
SSR SH + +S S G + R+ Q G+++S
Sbjct: 374 KEGSSR--------SHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQS 416
Score = 32.0 bits (71), Expect = 1.9
Identities = 56/267 (20%), Positives = 90/267 (33%), Gaps = 40/267 (14%)
Query: 410 YTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQ----- 464
Y G+ K + T G K K + K D+++RD QV
Sbjct: 72 YEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKC 131
Query: 465 HKQGQSQA-----------ASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLK------- 506
HK G ++SSV P P + + +A+ + +LK
Sbjct: 132 HKWGHVNTDRECPLFGLSGINASSV--PTDGSGPSMHPSELIAEMRNSGFALKRNVLGRN 189
Query: 507 LRIPIPPTDKSASKEELKMKIKVSSSERHSSSD---------EGSGKSKHSSPHISRDHK 557
L P + AS+ E +++ S E K K + +
Sbjct: 190 LTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSR 249
Query: 558 EKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSS-- 615
KHK+H SS +SS S S S S S + + G ++S S
Sbjct: 250 SKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEE 309
Query: 616 ---SSRKRLHVNDASHNHHSKMSKSSK 639
S +++LH + S +HH++ K
Sbjct: 310 KDKSKKRKLH-EELSSSHHNREKAKEK 335
Score = 30.4 bits (67), Expect = 5.5
Identities = 35/173 (20%), Positives = 57/173 (32%), Gaps = 20/173 (11%)
Query: 499 KEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRD--- 555
K+K L+ + K +++ K + S ++H SS S S SS + +
Sbjct: 219 KQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSS 278
Query: 556 -----------HKEKHKEHPSSRHHTS------SHKHSHSHSGSSSGGSKHSADGIPPTV 598
++K K++ S H+ S K H SS P
Sbjct: 279 ESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRF 338
Query: 599 LRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTSQHPR 651
L+ S S S + R H + + SS+S G S+ R
Sbjct: 339 LKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSR 391
>gi|221316599 chromogranin B precursor [Homo sapiens]
Length = 677
Score = 45.1 bits (105), Expect = 2e-04
Identities = 61/280 (21%), Positives = 97/280 (34%), Gaps = 57/280 (20%)
Query: 424 STTPGIIPQ-----KMSLDKYREKRKLETLDLD-----VRDHYIAAQVEQQHKQGQSQAA 473
S+ P I P+ K S ++K E + +RD A++ + +G++ A
Sbjct: 48 SSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAP 107
Query: 474 SSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSE 533
+ P K A+TEK+ E G + R P S ++ ++K SE
Sbjct: 108 GEEDIQGPTK-----ADTEKWA----EGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSE 158
Query: 534 RHSSSDEGS--GKSKHSSPHISRDHKEKHKEHPS------------------------SR 567
+ DE G++ +EKH E P S
Sbjct: 159 KSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSE 218
Query: 568 HHTSSHK----HSHSHSGSSSGGSKHSADGIPPTVLRSPVGL--SSDGISSSSSSSRKRL 621
H + H HS S SG S + P P S +G ++S KR
Sbjct: 219 THAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKR- 277
Query: 622 HVNDASHNHHSKMSKSSKSSGGLRTSQ---HPRETGQEAS 658
+HH + S GG S+ HP+E +E++
Sbjct: 278 --RTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESN 315
>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
Length = 951
Score = 45.1 bits (105), Expect = 2e-04
Identities = 63/281 (22%), Positives = 107/281 (38%), Gaps = 36/281 (12%)
Query: 398 DKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS-------LDKYREKRKLET-LD 449
D SD +E + S+ + P P ++ ++ L+ + K+KLE L
Sbjct: 601 DDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLA 660
Query: 450 LDVRDHYIAAQVEQQHKQGQSQAASSSSV-TSPIKMKIPIANTEKYMADKKEKSGSLKLR 508
R+ A E + KQ Q++ +++ +K +P A K S
Sbjct: 661 AAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTP 720
Query: 509 IPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSS-R 567
P+ + E+K + SS + +E K K + HK++ + S +
Sbjct: 721 CPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKK-------KKHKKRSRTRSRSPK 773
Query: 568 HHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDAS 627
+H+SS S SHS +KHS TV RS S S S R+R H +
Sbjct: 774 YHSSSKSRSRSHS-----KAKHSLPSAYRTVRRS---------RSRSRSPRRRAHSPERR 819
Query: 628 HNHHS-----KMSKSSKSSGGLRTSQHPRETGQEASGDQRS 663
S ++S+S +S S+ P E ++ R+
Sbjct: 820 REERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRT 860
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.124 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,934,002
Number of Sequences: 37866
Number of extensions: 1220300
Number of successful extensions: 7925
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 338
Number of HSP's that attempted gapping in prelim test: 5402
Number of HSP's gapped (non-prelim): 1655
length of query: 663
length of database: 18,247,518
effective HSP length: 109
effective length of query: 554
effective length of database: 14,120,124
effective search space: 7822548696
effective search space used: 7822548696
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.