Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 4502331

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]
         (418 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]            865   0.0  
gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]            367   e-101
gi|32307152 oxytocin receptor [Homo sapiens]                          360   2e-99
gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]   252   5e-67
gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo sap...   225   7e-59
gi|46395496 G protein-coupled receptor for asthma susceptibility...   152   7e-37
gi|46391085 G protein-coupled receptor for asthma susceptibility...   152   7e-37
gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Ho...   134   2e-31
gi|222080109 orexin receptor 2 [Homo sapiens]                         113   4e-25
gi|4502607 cholecystokinin A receptor [Homo sapiens]                  113   4e-25
gi|157738685 G protein-coupled receptor 103 [Homo sapiens]            107   3e-23
gi|63477962 opioid receptor, delta 1 [Homo sapiens]                   103   3e-22
gi|222080095 orexin receptor 1 [Homo sapiens]                         100   2e-21
gi|149944554 somatostatin receptor 4 [Homo sapiens]                   100   2e-21
gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]       98   1e-20
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]      97   3e-20
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]       96   5e-20
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]        96   5e-20
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]      96   5e-20
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]      96   5e-20
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]      96   5e-20
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]       96   5e-20
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]      96   5e-20
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]       96   5e-20
gi|167000885 galanin receptor 1 [Homo sapiens]                         96   6e-20
gi|4557857 somatostatin receptor 1 [Homo sapiens]                      96   8e-20
gi|4557865 somatostatin receptor 5 [Homo sapiens]                      95   1e-19
gi|4885057 apelin receptor [Homo sapiens]                              94   2e-19
gi|4505513 opiate receptor-like 1 [Homo sapiens]                       94   2e-19
gi|33286424 opiate receptor-like 1 [Homo sapiens]                      94   2e-19

>gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]
          Length = 418

 Score =  865 bits (2234), Expect = 0.0
 Identities = 418/418 (100%), Positives = 418/418 (100%)

Query: 1   MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV 60
           MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
Sbjct: 1   MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV 60

Query: 61  TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP 120
           TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
Sbjct: 61  TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP 120

Query: 121 DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV 180
           DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
Sbjct: 121 DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV 180

Query: 181 LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC 240
           LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
Sbjct: 181 LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC 240

Query: 241 YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY 300
           YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
Sbjct: 241 YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY 300

Query: 301 IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV 360
           IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
Sbjct: 301 IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV 360

Query: 361 QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST 418
           QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
Sbjct: 361 QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST 418


>gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]
          Length = 424

 Score =  367 bits (942), Expect = e-101
 Identities = 190/351 (54%), Positives = 237/351 (67%), Gaps = 12/351 (3%)

Query: 46  RNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQV 105
           R+EELAK+EI VLA    +A  GN +VLL L +  RK SRMHLF+ HL+L DLAVA FQV
Sbjct: 29  RDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQV 88

Query: 106 LPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPAR 165
           LPQ+ WDITYRF+GPD LCR VK+LQV  MFAS YML+ MT DRY+AVCHPL++LQQP +
Sbjct: 89  LPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQ 148

Query: 166 RSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIF 225
            + L+IAA W+L+ + S PQ F+FS+ EV   +   DCWA F  PWG RAY+TW T  IF
Sbjct: 149 STYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIF 208

Query: 226 VAPVVILGTCYGFICYNIWCNVRGKTASRQSKG---------AEQAGVAFQKGFLLAPCV 276
           V PV +L  CY  IC+ I  N++ KT + +  G         +     A  +G  L   V
Sbjct: 209 VLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRG--LPSRV 266

Query: 277 SSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALL 336
           SS+ +ISRAKIRTVKMTFVIV AYI CWAPFF +QMWSVWD  +   +S N   TI+ LL
Sbjct: 267 SSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLL 326

Query: 337 GSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTD-SMSRRQT 386
           G+LNSCCNPWIYM F+ HLL   ++   CC   + +  +  +D S+S R T
Sbjct: 327 GNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHT 377


>gi|32307152 oxytocin receptor [Homo sapiens]
          Length = 389

 Score =  360 bits (923), Expect = 2e-99
 Identities = 185/363 (50%), Positives = 243/363 (66%), Gaps = 15/363 (4%)

Query: 37  EGN---GPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHL 93
           EGN   GPPR  RNE LA++E+AVL +   +A+ GN+ VLLAL  T +K SR+  F++HL
Sbjct: 24  EGNRTAGPPR--RNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHL 81

Query: 94  SLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAV 153
           S+ADL VA FQVLPQ+ WDIT+RF GPD LCR+VK+LQV GMFAS Y+L++M+ DR +A+
Sbjct: 82  SIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAI 141

Query: 154 CHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGS 213
           C PL++L++  R  RL + A W+   V S PQ  +FS+ EV +     DCWA FIQPWG 
Sbjct: 142 CQPLRSLRR--RTDRLAVLATWLGCLVASAPQVHIFSLREVAD--GVFDCWAVFIQPWGP 197

Query: 214 RAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLA 273
           +AY+TW+T  +++ PV++L  CYG I + IW N+R KTA+  +  A +   A   G +  
Sbjct: 198 KAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVAL 257

Query: 274 PCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITIT 333
             VSSVK IS+AKIRTVKMTF+IV A+IVCW PFF +QMWSVWD  +     E     I 
Sbjct: 258 ARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANA---PKEASAFIIV 314

Query: 334 ALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRR---QTFYSN 390
            LL SLNSCCNPWIYM F+GHL  + VQ F CC     K  +    S S++    +F  +
Sbjct: 315 MLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLS 374

Query: 391 NRS 393
           +RS
Sbjct: 375 HRS 377


>gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]
          Length = 371

 Score =  252 bits (643), Expect = 5e-67
 Identities = 136/340 (40%), Positives = 187/340 (55%), Gaps = 40/340 (11%)

Query: 42  PRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKT--SRMHLFIRHLSLADLA 99
           P D R+  LA+ E+A+L++ F    L N  VL AL R  R+   + +H+FI HL LADLA
Sbjct: 28  PLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLA 87

Query: 100 VAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKT 159
           VA FQVLPQ+ W  T RFRGPD LCR VK+LQ+ GM+AS+YM++ MT DR+ A+C P+  
Sbjct: 88  VALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLA 147

Query: 160 LQQPARRS-RLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVT 218
            +  +       +  AW  S +LS PQ F+F+   V   +   DCWA F +PWG R YVT
Sbjct: 148 YRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVT 207

Query: 219 WMTGGIFVAPVVILGTCYGFICYNIWCNV------------RGKTASRQSKGAEQAGVAF 266
           W+   +FVAP + +  C   I   I  ++            RG+      +GA       
Sbjct: 208 WIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAH------ 261

Query: 267 QKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESE 326
                          +S A  +TV+MT VIV  Y++CWAPFF++Q+W+ WDP +     E
Sbjct: 262 ---------------VSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA---PLE 303

Query: 327 NPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCC 366
                +  LL SLNSC NPWIY  FS  +  + ++S  CC
Sbjct: 304 GAPFVLLMLLASLNSCTNPWIYASFSSSVSSE-LRSLLCC 342


>gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo
           sapiens]
          Length = 309

 Score =  225 bits (573), Expect = 7e-59
 Identities = 118/292 (40%), Positives = 162/292 (55%), Gaps = 36/292 (12%)

Query: 42  PRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKT--SRMHLFIRHLSLADLA 99
           P D R+  LA+ E+A+L++ F    L N  VL AL R  R+   + +H+FI HL LADLA
Sbjct: 28  PLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLA 87

Query: 100 VAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKT 159
           VA FQVLPQ+ W  T RFRGPD LCR VK+LQ+ GM+AS+YM++ MT DR+ A+C P+  
Sbjct: 88  VALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLA 147

Query: 160 LQQ-PARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVT 218
            +          +  AW  S +LS PQ F+F+   V   +   DCWA F +PWG R YVT
Sbjct: 148 YRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVT 207

Query: 219 WMTGGIFVAPVVILGTCYGFICYNIWCNV------------RGKTASRQSKGAEQAGVAF 266
           W+   +FVAP + +  C   I   I  ++            RG+      +GA       
Sbjct: 208 WIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAH------ 261

Query: 267 QKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDP 318
                          +S A  +TV+MT VIV  Y++CWAPFF++Q+W+ WDP
Sbjct: 262 ---------------VSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDP 298


>gi|46395496 G protein-coupled receptor for asthma susceptibility
           isoform A [Homo sapiens]
          Length = 371

 Score =  152 bits (383), Expect = 7e-37
 Identities = 96/314 (30%), Positives = 159/314 (50%), Gaps = 26/314 (8%)

Query: 54  EIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDI 113
           ++  L V F   ++GNS VL +  R  +K SRM  F+  L++ D       +L  + W  
Sbjct: 52  QLITLWVLFVFTIVGNSVVLFSTWRRKKK-SRMTFFVTQLAITDSFTGLVNILTDINWRF 110

Query: 114 TYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAA 173
           T  F  PD +CRVV++LQV  ++AS Y+LV ++ DRY A+ +P+K L Q  +++R++I  
Sbjct: 111 TGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFL-QGEKQARVLIVI 169

Query: 174 AWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILG 233
           AW LSF+ S P   +F    ++N      CWA +        Y+T +   ++  P+ I+ 
Sbjct: 170 AWSLSFLFSIPTLIIFGKRTLSN--GEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIIS 227

Query: 234 TCYGFICYNIWCNVRGKTASRQSKGAEQAGV--AFQKGFLLAPCVSSVKSISRAKIRTVK 291
             YG +   IW  ++ KT            +  ++ +G            IS+AKI+ +K
Sbjct: 228 IMYGIVIRTIW--IKSKTYETVISNCSDGKLCSSYNRGL-----------ISKAKIKAIK 274

Query: 292 MTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFF 351
            + +I+ A+I CW+P+F+  +   ++ +    E    ++ I   L +LNS  NP IY  F
Sbjct: 275 YSIIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQN-LPALNSAINPLIYCVF 333

Query: 352 SGHLLQDCVQSFPC 365
           S  +      SFPC
Sbjct: 334 SSSI------SFPC 341


>gi|46391085 G protein-coupled receptor for asthma susceptibility
           isoform B [Homo sapiens]
          Length = 377

 Score =  152 bits (383), Expect = 7e-37
 Identities = 96/314 (30%), Positives = 159/314 (50%), Gaps = 26/314 (8%)

Query: 54  EIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDI 113
           ++  L V F   ++GNS VL +  R  +K SRM  F+  L++ D       +L  + W  
Sbjct: 52  QLITLWVLFVFTIVGNSVVLFSTWRRKKK-SRMTFFVTQLAITDSFTGLVNILTDINWRF 110

Query: 114 TYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAA 173
           T  F  PD +CRVV++LQV  ++AS Y+LV ++ DRY A+ +P+K L Q  +++R++I  
Sbjct: 111 TGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFL-QGEKQARVLIVI 169

Query: 174 AWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILG 233
           AW LSF+ S P   +F    ++N      CWA +        Y+T +   ++  P+ I+ 
Sbjct: 170 AWSLSFLFSIPTLIIFGKRTLSN--GEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIIS 227

Query: 234 TCYGFICYNIWCNVRGKTASRQSKGAEQAGV--AFQKGFLLAPCVSSVKSISRAKIRTVK 291
             YG +   IW  ++ KT            +  ++ +G            IS+AKI+ +K
Sbjct: 228 IMYGIVIRTIW--IKSKTYETVISNCSDGKLCSSYNRGL-----------ISKAKIKAIK 274

Query: 292 MTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFF 351
            + +I+ A+I CW+P+F+  +   ++ +    E    ++ I   L +LNS  NP IY  F
Sbjct: 275 YSIIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQN-LPALNSAINPLIYCVF 333

Query: 352 SGHLLQDCVQSFPC 365
           S  +      SFPC
Sbjct: 334 SSSI------SFPC 341


>gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Homo
           sapiens]
          Length = 328

 Score =  134 bits (337), Expect = 2e-31
 Identities = 85/313 (27%), Positives = 153/313 (48%), Gaps = 33/313 (10%)

Query: 52  KLEIAVLAVTFAVAVLGNSSVLLALHRTP------RKTSRMHLFIRHLSLADLAVAFFQV 105
           K+ + V    F ++   N+S LL L +        +K SRM L ++HL+LA+L      +
Sbjct: 36  KIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVM 95

Query: 106 LPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPAR 165
                W+IT ++   + LC+V+ +L++F M+A A+M+VV++ DR +A+  PL  L+  ++
Sbjct: 96  PLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPL-ALKSNSK 154

Query: 166 RSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWA------TFIQPWGSRAYVTW 219
             + M+  AW+LS V + PQ ++F MI + + +     ++      +F Q W    Y  +
Sbjct: 155 VGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFF 214

Query: 220 MTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSV 279
               +F+ P+ I+  C   I + +   +       Q                      S 
Sbjct: 215 TFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLN-------------------QSK 255

Query: 280 KSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSL 339
            +I RA+++T+KMT    T++ VCW P++++ +W  +DP  +     +P      L   L
Sbjct: 256 NNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDP-EMLNRLSDPVNHFFFLFAFL 314

Query: 340 NSCCNPWIYMFFS 352
           N C +P IY +FS
Sbjct: 315 NPCFDPLIYGYFS 327


>gi|222080109 orexin receptor 2 [Homo sapiens]
          Length = 444

 Score =  113 bits (282), Expect = 4e-25
 Identities = 97/382 (25%), Positives = 166/382 (43%), Gaps = 26/382 (6%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           IA   + F VA++GN  V +A+ +     +  + FI +LSLAD+ V    +   +  DIT
Sbjct: 58  IAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDIT 117

Query: 115 YRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAA 174
             +     LC+V+ +LQ   +  S   L  +  DR+ A+CHPL   +  A+R+R  I   
Sbjct: 118 ETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPL-MFKSTAKRARNSIVII 176

Query: 175 WVLSFVLSTPQYFVFSMIEV-----NNVTKARDC---WATFIQPWGSRAYVTWMTGGIFV 226
           W++S ++  PQ  V     V     N  T    C   W   I P   + Y        ++
Sbjct: 177 WIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYP---KMYHICFFLVTYM 233

Query: 227 APVVILGTCYGFICYNIWC-NVRGKTASRQSKGAEQAGVAFQKG------FLLAPCVSSV 279
           AP+ ++   Y  I   +WC  + G ++  Q K      V+  +G        ++   + +
Sbjct: 234 APLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEI 293

Query: 280 KSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPT---ITITALL 336
           K I RA+ +T +M  +++  + +C+ P  I+ +      M   TE         T +  L
Sbjct: 294 KQI-RARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWL 352

Query: 337 GSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTN 396
              NS  NP IY F SG   ++   +F CC       +    D ++R +T   + +S T 
Sbjct: 353 VYANSAANPIIYNFLSGKFREEFKAAFSCC---CLGVHHRQEDRLTRGRTSTESRKSLTT 409

Query: 397 STGMWKDSPKSSKSIKFIPVST 418
               + +  K S+ +    +ST
Sbjct: 410 QISNFDNISKLSEQVVLTSIST 431


>gi|4502607 cholecystokinin A receptor [Homo sapiens]
          Length = 428

 Score =  113 bits (282), Expect = 4e-25
 Identities = 84/351 (23%), Positives = 155/351 (44%), Gaps = 38/351 (10%)

Query: 53  LEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWD 112
           ++I + ++ F ++VLGN+ V+  L R  R  +  ++F+  L+++DL +  F +   +  +
Sbjct: 43  VQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPN 102

Query: 113 ITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKT-LQQPARRSRLMI 171
           +   F     +C+   +     +  S + LV ++ +RY A+C PL++ + Q    +  +I
Sbjct: 103 LLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVI 162

Query: 172 AAAWVLSFVLSTPQYFVFSMI---EVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAP 228
           AA W LSF + TP Y ++S +     NN   A  C          +++ T++   +F+ P
Sbjct: 163 AATWCLSFTIMTP-YPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIP 221

Query: 229 VVILGTCYGFICYNIWCNVRGKTASRQS------------KGAEQAGVAFQKGFLLAPCV 276
            +++   YG I   ++  ++ + + ++S            K  +  G   QK     P  
Sbjct: 222 GIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQK--TRPPRK 279

Query: 277 SSVKSIS-------------------RAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWD 317
             ++ +S                    AK R ++M  VIV  + +CW P F    W  +D
Sbjct: 280 LELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYD 339

Query: 318 PMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQN 368
             S         I+   LL   +SC NP IY F +       + +FPCC N
Sbjct: 340 TASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPN 390


>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
          Length = 431

 Score =  107 bits (266), Expect = 3e-23
 Identities = 86/364 (23%), Positives = 162/364 (44%), Gaps = 37/364 (10%)

Query: 51  AKLEIAVLAVT-FAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQM 109
           AKL + +  V  FA+A+ GN+ V   + R+    +  ++FI  L+L+DL + FF +   M
Sbjct: 44  AKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTM 103

Query: 110 CWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLK-TLQQPARRSR 168
             +I+  + G  ++C++V  +Q   +      +  +  +R+  + HP K   Q   RR+ 
Sbjct: 104 LQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAF 163

Query: 169 LMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARD---CWATFIQPWGSRAYVTWMTGGIF 225
            M+   W+++ ++ +P + V  +    +    ++   C   +  P   + Y T++   +F
Sbjct: 164 TMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILF 223

Query: 226 VAPVVILGTCYGFICYNIWCNVRGKTAS--RQSKGAEQAGVAFQKGFLLAPCVSSVKSIS 283
           + P++++   Y  I Y +W   R    S  R   G E                  +  I+
Sbjct: 224 LLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKE------------------MSKIA 265

Query: 284 RAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTI----TITALLGSL 339
           R K R V M   +V  + VCWAPF ++ M   +       E ++ TI     I  ++G  
Sbjct: 266 RKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFE--KEYDDVTIKMIFAIVQIIGFS 323

Query: 340 NSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTD-----SMSRRQTFYSNNRSP 394
           NS CNP +Y F + +  ++ V S  C   + + F+          +M R++  +S   +P
Sbjct: 324 NSICNPIVYAFMNENFKKN-VLSAVCYCIVNKTFSPAQRHGNSGITMMRKKAKFSLRENP 382

Query: 395 TNST 398
              T
Sbjct: 383 VEET 386


>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
          Length = 372

 Score =  103 bits (257), Expect = 3e-22
 Identities = 105/404 (25%), Positives = 172/404 (42%), Gaps = 68/404 (16%)

Query: 8   DAGPSGNSSPWWPLATGAGNTSREA--EALGEGNGPP--RDVRNEELAKLEIAVLAVTFA 63
           +  PS  +    PL   A +    A   A    +GPP  R   +  LA    A+ +   A
Sbjct: 2   EPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCA 61

Query: 64  VAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWL 123
           V +LGN  V+  + R  +  +  +++I +L+LAD A+A   +  Q    +   +   + L
Sbjct: 62  VGLLGNVLVMFGIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSAKYLMETWPFGELL 120

Query: 124 CRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLMIAAAWVLSFVLS 182
           C+ V  +  + MF S + L +M+ DRYIAVCHP+K L  +   +++L+    WVL+  + 
Sbjct: 121 CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG 180

Query: 183 TPQYFVFSMIEVNNVTKARD----CWATFIQP---WGSRAYVTWMTGGIFVAPVVILGTC 235
            P       I V  VT+ RD    C   F  P   W +   +       FV P++I+  C
Sbjct: 181 VP-------IMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFA-FVVPILIITVC 232

Query: 236 YGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFV 295
           YG +   +  +VR                           +S  K   R+  R  +M  V
Sbjct: 233 YGLMLLRL-RSVR--------------------------LLSGSKEKDRSLRRITRMVLV 265

Query: 296 IVTAYIVCWAPFFI-IQMWSVWDPMSVWTESENPTIT----ITALLGSLNSCCNPWIYMF 350
           +V A++VCWAP  I + +W++ D      +  +P +     +   LG  NS  NP +Y F
Sbjct: 266 VVGAFVVCWAPIHIFVIVWTLVD-----IDRRDPLVVAALHLCIALGYANSSLNPVLYAF 320

Query: 351 FSGHLLQDCVQSFPCC--QNMKEKFNKEDTDSMSRRQTFYSNNR 392
                     ++F  C  Q  ++   + D  S SR +   +  R
Sbjct: 321 LD--------ENFKRCFRQLCRKPCGRPDPSSFSRAREATARER 356


>gi|222080095 orexin receptor 1 [Homo sapiens]
          Length = 425

 Score =  100 bits (250), Expect = 2e-21
 Identities = 87/333 (26%), Positives = 148/333 (44%), Gaps = 27/333 (8%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           IA     F VA++GN+ V LA+ R     +  + FI +LSLAD+ V    +   +  DIT
Sbjct: 50  IAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDIT 109

Query: 115 YRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAA 174
             +     LC+V+ +LQ   +  +   L  +  DR+ A+CHPL   +  ARR+R  I   
Sbjct: 110 ESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPL-LFKSTARRARGSILGI 168

Query: 175 WVLSFVLSTPQYFVFS----MIEVNNVTK----ARDCWATFIQPWGSRAYVTWMTGGIFV 226
           W +S  +  PQ  V      + E+ N T+      + WA  + P   + Y +      ++
Sbjct: 169 WAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYP---KIYHSCFFIVTYL 225

Query: 227 APVVILGTCYGFICYNIW---------CNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVS 277
           AP+ ++   Y  I   +W           VR         G  + G++ +        ++
Sbjct: 226 APLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLA 285

Query: 278 SVKSISRAKIRTVKMTFVIVTAYIVCWAPFFII----QMWSVWDPMSVWTESENPTITIT 333
            VK + RA+ +T KM  V++  + +C+ P  ++    +++ ++   S   E+     T +
Sbjct: 286 EVKQM-RARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASD-REAVYACFTFS 343

Query: 334 ALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCC 366
             L   NS  NP IY F SG   +    +F CC
Sbjct: 344 HWLVYANSAANPIIYNFLSGKFREQFKAAFSCC 376


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score =  100 bits (249), Expect = 2e-21
 Identities = 84/354 (23%), Positives = 160/354 (45%), Gaps = 54/354 (15%)

Query: 7   PDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAV 66
           P  G  G  + W P A  A +   EAE    G   P D R   +  ++  + A+   V +
Sbjct: 8   PPGGEEGLGTAW-PSAANASSAPAEAEEAVAG---PGDARAAGMVAIQ-CIYALVCLVGL 62

Query: 67  LGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDW---- 122
           +GN+ V+  + R  +  +  ++++ +L++AD    F   +P +      R     W    
Sbjct: 63  VGNALVIFVILRYAKMKTATNIYLLNLAVAD--ELFMLSVPFVASSAALRH----WPFGS 116

Query: 123 -LCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLK--TLQQPARRSRLMIAAAWVLSF 179
            LCR V  +    MF S + L V++ DRY+AV HPL+  T ++P+  ++L+    W+ S 
Sbjct: 117 VLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPS-VAKLINLGVWLASL 175

Query: 180 VLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFI 239
           +++ P   +F+        +A  C   +  P  S  +V +     F+ PV+ +G CY  I
Sbjct: 176 LVTLP-IAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLI 234

Query: 240 CYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTA 299
                               +   VA + G+         +   R++ +  ++  ++V  
Sbjct: 235 V------------------GKMRAVALRAGW---------QQRRRSEKKITRLVLMVVVV 267

Query: 300 YIVCWAPFFIIQMWSVWDPMSVWTESENPTIT-ITALLGSLNSCCNPWIYMFFS 352
           +++CW PF+++Q+      ++++  S + T+  ++ +L   NSC NP +Y F S
Sbjct: 268 FVLCWMPFYVVQL------LNLFVTSLDATVNHVSLILSYANSCANPILYGFLS 315


>gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]
          Length = 418

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 92/368 (25%), Positives = 154/368 (41%), Gaps = 68/368 (18%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           +A+ ++   V + GN  V+  + R  +  +  +++I +L+LAD A+A   +  Q    + 
Sbjct: 74  MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLM 132

Query: 115 YRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLMIAA 173
             +     LC++V  +  + MF S + L  M+ DRYIAVCHP+K L  +  R ++++   
Sbjct: 133 GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC 192

Query: 174 AWVLSFVLSTPQYFVFSMIEVNNVTKAR----DCWATFIQPWGSRAYVTWMTGGI----- 224
            W+LS  +  P  F+ +       TK R    DC  TF  P       TW    +     
Sbjct: 193 NWILSSAIGLPVMFMAT-------TKYRQGSIDCTLTFSHP-------TWYWENLLKICV 238

Query: 225 ----FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVK 280
               F+ PV+I+  CYG +   +  +VR                           +S  K
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-KSVR--------------------------MLSGSK 271

Query: 281 SISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTIT--ITALLGS 338
              R   R  +M  V+V  +IVCW P   I ++ +   +    E+   T++      LG 
Sbjct: 272 EKDRNLRRITRMVLVVVAVFIVCWTP---IHIYVIIKALVTIPETTFQTVSWHFCIALGY 328

Query: 339 LNSCCNPWIYMFFSGHLLQDCVQSF--PCCQNMKE----KFNKEDTDSMSRRQTFYSNNR 392
            NSC NP +Y F   +  + C + F  P   N+++    +  +   D  S   T    N 
Sbjct: 329 TNSCLNPVLYAFLDEN-FKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNH 387

Query: 393 SPTNSTGM 400
            P  +  M
Sbjct: 388 QPPLAVSM 395


>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
          Length = 403

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 65/363 (17%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           +A+ ++   V + GN  V+  + R  +  +  +++I +L+LAD A+A   +  Q    + 
Sbjct: 74  MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLM 132

Query: 115 YRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLMIAA 173
             +     LC++V  +  + MF S + L  M+ DRYIAVCHP+K L  +  R ++++   
Sbjct: 133 GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC 192

Query: 174 AWVLSFVLSTPQYFVFSMIEVNNVTKAR----DCWATFIQPWGSRAYVTWMTGGI----- 224
            W+LS  +  P  F+ +       TK R    DC  TF  P       TW    +     
Sbjct: 193 NWILSSAIGLPVMFMAT-------TKYRQGSIDCTLTFSHP-------TWYWENLLKICV 238

Query: 225 ----FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVK 280
               F+ PV+I+  CYG +   +  +VR                           +S  K
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-KSVR--------------------------MLSGSK 271

Query: 281 SISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTIT--ITALLGS 338
              R   R  +M  V+V  +IVCW P   I ++ +   +    E+   T++      LG 
Sbjct: 272 EKDRNLRRITRMVLVVVAVFIVCWTP---IHIYVIIKALVTIPETTFQTVSWHFCIALGY 328

Query: 339 LNSCCNPWIYMFFSGHLLQDCVQSF--PCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTN 396
            NSC NP +Y F   +  + C + F  P   N++++ N       +R     +N    TN
Sbjct: 329 TNSCLNPVLYAFLDEN-FKRCFREFCIPTSSNIEQQ-NSTRIRQNTRDHPSTANTVDRTN 386

Query: 397 STG 399
             G
Sbjct: 387 HQG 389


>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
          Length = 493

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 86/336 (25%), Positives = 146/336 (43%), Gaps = 64/336 (19%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           +A+ ++   V + GN  V+  + R  +  +  +++I +L+LAD A+A   +  Q    + 
Sbjct: 167 MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLM 225

Query: 115 YRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLMIAA 173
             +     LC++V  +  + MF S + L  M+ DRYIAVCHP+K L  +  R ++++   
Sbjct: 226 GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC 285

Query: 174 AWVLSFVLSTPQYFVFSMIEVNNVTKAR----DCWATFIQPWGSRAYVTWMTGGI----- 224
            W+LS  +  P  F+ +       TK R    DC  TF  P       TW    +     
Sbjct: 286 NWILSSAIGLPVMFMAT-------TKYRQGSIDCTLTFSHP-------TWYWENLLKICV 331

Query: 225 ----FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVK 280
               F+ PV+I+  CYG +   +  +VR                           +S  K
Sbjct: 332 FIFAFIMPVLIITVCYGLMILRL-KSVR--------------------------MLSGSK 364

Query: 281 SISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTIT--ITALLGS 338
              R   R  +M  V+V  +IVCW P   I ++ +   +    E+   T++      LG 
Sbjct: 365 EKDRNLRRITRMVLVVVAVFIVCWTP---IHIYVIIKALVTIPETTFQTVSWHFCIALGY 421

Query: 339 LNSCCNPWIYMFFSGHLLQDCVQSF--PCCQNMKEK 372
            NSC NP +Y F   +  + C + F  P   N++++
Sbjct: 422 TNSCLNPVLYAFLDEN-FKRCFREFCIPTSSNIEQQ 456


>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
          Length = 400

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 86/336 (25%), Positives = 146/336 (43%), Gaps = 64/336 (19%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           +A+ ++   V + GN  V+  + R  +  +  +++I +L+LAD A+A   +  Q    + 
Sbjct: 74  MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLM 132

Query: 115 YRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLMIAA 173
             +     LC++V  +  + MF S + L  M+ DRYIAVCHP+K L  +  R ++++   
Sbjct: 133 GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC 192

Query: 174 AWVLSFVLSTPQYFVFSMIEVNNVTKAR----DCWATFIQPWGSRAYVTWMTGGI----- 224
            W+LS  +  P  F+ +       TK R    DC  TF  P       TW    +     
Sbjct: 193 NWILSSAIGLPVMFMAT-------TKYRQGSIDCTLTFSHP-------TWYWENLLKICV 238

Query: 225 ----FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVK 280
               F+ PV+I+  CYG +   +  +VR                           +S  K
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-KSVR--------------------------MLSGSK 271

Query: 281 SISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTIT--ITALLGS 338
              R   R  +M  V+V  +IVCW P   I ++ +   +    E+   T++      LG 
Sbjct: 272 EKDRNLRRITRMVLVVVAVFIVCWTP---IHIYVIIKALVTIPETTFQTVSWHFCIALGY 328

Query: 339 LNSCCNPWIYMFFSGHLLQDCVQSF--PCCQNMKEK 372
            NSC NP +Y F   +  + C + F  P   N++++
Sbjct: 329 TNSCLNPVLYAFLDEN-FKRCFREFCIPTSSNIEQQ 363


>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
          Length = 420

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 86/336 (25%), Positives = 146/336 (43%), Gaps = 64/336 (19%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           +A+ ++   V + GN  V+  + R  +  +  +++I +L+LAD A+A   +  Q    + 
Sbjct: 74  MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLM 132

Query: 115 YRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLMIAA 173
             +     LC++V  +  + MF S + L  M+ DRYIAVCHP+K L  +  R ++++   
Sbjct: 133 GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC 192

Query: 174 AWVLSFVLSTPQYFVFSMIEVNNVTKAR----DCWATFIQPWGSRAYVTWMTGGI----- 224
            W+LS  +  P  F+ +       TK R    DC  TF  P       TW    +     
Sbjct: 193 NWILSSAIGLPVMFMAT-------TKYRQGSIDCTLTFSHP-------TWYWENLLKICV 238

Query: 225 ----FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVK 280
               F+ PV+I+  CYG +   +  +VR                           +S  K
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-KSVR--------------------------MLSGSK 271

Query: 281 SISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTIT--ITALLGS 338
              R   R  +M  V+V  +IVCW P   I ++ +   +    E+   T++      LG 
Sbjct: 272 EKDRNLRRITRMVLVVVAVFIVCWTP---IHIYVIIKALVTIPETTFQTVSWHFCIALGY 328

Query: 339 LNSCCNPWIYMFFSGHLLQDCVQSF--PCCQNMKEK 372
            NSC NP +Y F   +  + C + F  P   N++++
Sbjct: 329 TNSCLNPVLYAFLDEN-FKRCFREFCIPTSSNIEQQ 363


>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
          Length = 397

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 86/336 (25%), Positives = 146/336 (43%), Gaps = 64/336 (19%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           +A+ ++   V + GN  V+  + R  +  +  +++I +L+LAD A+A   +  Q    + 
Sbjct: 74  MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLM 132

Query: 115 YRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLMIAA 173
             +     LC++V  +  + MF S + L  M+ DRYIAVCHP+K L  +  R ++++   
Sbjct: 133 GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC 192

Query: 174 AWVLSFVLSTPQYFVFSMIEVNNVTKAR----DCWATFIQPWGSRAYVTWMTGGI----- 224
            W+LS  +  P  F+ +       TK R    DC  TF  P       TW    +     
Sbjct: 193 NWILSSAIGLPVMFMAT-------TKYRQGSIDCTLTFSHP-------TWYWENLLKICV 238

Query: 225 ----FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVK 280
               F+ PV+I+  CYG +   +  +VR                           +S  K
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-KSVR--------------------------MLSGSK 271

Query: 281 SISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTIT--ITALLGS 338
              R   R  +M  V+V  +IVCW P   I ++ +   +    E+   T++      LG 
Sbjct: 272 EKDRNLRRITRMVLVVVAVFIVCWTP---IHIYVIIKALVTIPETTFQTVSWHFCIALGY 328

Query: 339 LNSCCNPWIYMFFSGHLLQDCVQSF--PCCQNMKEK 372
            NSC NP +Y F   +  + C + F  P   N++++
Sbjct: 329 TNSCLNPVLYAFLDEN-FKRCFREFCIPTSSNIEQQ 363


>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
          Length = 406

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 86/336 (25%), Positives = 146/336 (43%), Gaps = 64/336 (19%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           +A+ ++   V + GN  V+  + R  +  +  +++I +L+LAD A+A   +  Q    + 
Sbjct: 74  MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLM 132

Query: 115 YRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLMIAA 173
             +     LC++V  +  + MF S + L  M+ DRYIAVCHP+K L  +  R ++++   
Sbjct: 133 GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC 192

Query: 174 AWVLSFVLSTPQYFVFSMIEVNNVTKAR----DCWATFIQPWGSRAYVTWMTGGI----- 224
            W+LS  +  P  F+ +       TK R    DC  TF  P       TW    +     
Sbjct: 193 NWILSSAIGLPVMFMAT-------TKYRQGSIDCTLTFSHP-------TWYWENLLKICV 238

Query: 225 ----FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVK 280
               F+ PV+I+  CYG +   +  +VR                           +S  K
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-KSVR--------------------------MLSGSK 271

Query: 281 SISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTIT--ITALLGS 338
              R   R  +M  V+V  +IVCW P   I ++ +   +    E+   T++      LG 
Sbjct: 272 EKDRNLRRITRMVLVVVAVFIVCWTP---IHIYVIIKALVTIPETTFQTVSWHFCIALGY 328

Query: 339 LNSCCNPWIYMFFSGHLLQDCVQSF--PCCQNMKEK 372
            NSC NP +Y F   +  + C + F  P   N++++
Sbjct: 329 TNSCLNPVLYAFLDEN-FKRCFREFCIPTSSNIEQQ 363


>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
          Length = 392

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 86/336 (25%), Positives = 146/336 (43%), Gaps = 64/336 (19%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           +A+ ++   V + GN  V+  + R  +  +  +++I +L+LAD A+A   +  Q    + 
Sbjct: 74  MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLM 132

Query: 115 YRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLMIAA 173
             +     LC++V  +  + MF S + L  M+ DRYIAVCHP+K L  +  R ++++   
Sbjct: 133 GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC 192

Query: 174 AWVLSFVLSTPQYFVFSMIEVNNVTKAR----DCWATFIQPWGSRAYVTWMTGGI----- 224
            W+LS  +  P  F+ +       TK R    DC  TF  P       TW    +     
Sbjct: 193 NWILSSAIGLPVMFMAT-------TKYRQGSIDCTLTFSHP-------TWYWENLLKICV 238

Query: 225 ----FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVK 280
               F+ PV+I+  CYG +   +  +VR                           +S  K
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-KSVR--------------------------MLSGSK 271

Query: 281 SISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTIT--ITALLGS 338
              R   R  +M  V+V  +IVCW P   I ++ +   +    E+   T++      LG 
Sbjct: 272 EKDRNLRRITRMVLVVVAVFIVCWTP---IHIYVIIKALVTIPETTFQTVSWHFCIALGY 328

Query: 339 LNSCCNPWIYMFFSGHLLQDCVQSF--PCCQNMKEK 372
            NSC NP +Y F   +  + C + F  P   N++++
Sbjct: 329 TNSCLNPVLYAFLDEN-FKRCFREFCIPTSSNIEQQ 363


>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
          Length = 389

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 86/336 (25%), Positives = 146/336 (43%), Gaps = 64/336 (19%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           +A+ ++   V + GN  V+  + R  +  +  +++I +L+LAD A+A   +  Q    + 
Sbjct: 74  MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLM 132

Query: 115 YRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLMIAA 173
             +     LC++V  +  + MF S + L  M+ DRYIAVCHP+K L  +  R ++++   
Sbjct: 133 GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC 192

Query: 174 AWVLSFVLSTPQYFVFSMIEVNNVTKAR----DCWATFIQPWGSRAYVTWMTGGI----- 224
            W+LS  +  P  F+ +       TK R    DC  TF  P       TW    +     
Sbjct: 193 NWILSSAIGLPVMFMAT-------TKYRQGSIDCTLTFSHP-------TWYWENLLKICV 238

Query: 225 ----FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVK 280
               F+ PV+I+  CYG +   +  +VR                           +S  K
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-KSVR--------------------------MLSGSK 271

Query: 281 SISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTIT--ITALLGS 338
              R   R  +M  V+V  +IVCW P   I ++ +   +    E+   T++      LG 
Sbjct: 272 EKDRNLRRITRMVLVVVAVFIVCWTP---IHIYVIIKALVTIPETTFQTVSWHFCIALGY 328

Query: 339 LNSCCNPWIYMFFSGHLLQDCVQSF--PCCQNMKEK 372
            NSC NP +Y F   +  + C + F  P   N++++
Sbjct: 329 TNSCLNPVLYAFLDEN-FKRCFREFCIPTSSNIEQQ 363


>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
          Length = 446

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 86/336 (25%), Positives = 146/336 (43%), Gaps = 64/336 (19%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           +A+ ++   V + GN  V+  + R  +  +  +++I +L+LAD A+A   +  Q    + 
Sbjct: 74  MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLM 132

Query: 115 YRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLMIAA 173
             +     LC++V  +  + MF S + L  M+ DRYIAVCHP+K L  +  R ++++   
Sbjct: 133 GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC 192

Query: 174 AWVLSFVLSTPQYFVFSMIEVNNVTKAR----DCWATFIQPWGSRAYVTWMTGGI----- 224
            W+LS  +  P  F+ +       TK R    DC  TF  P       TW    +     
Sbjct: 193 NWILSSAIGLPVMFMAT-------TKYRQGSIDCTLTFSHP-------TWYWENLLKICV 238

Query: 225 ----FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVK 280
               F+ PV+I+  CYG +   +  +VR                           +S  K
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-KSVR--------------------------MLSGSK 271

Query: 281 SISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTIT--ITALLGS 338
              R   R  +M  V+V  +IVCW P   I ++ +   +    E+   T++      LG 
Sbjct: 272 EKDRNLRRITRMVLVVVAVFIVCWTP---IHIYVIIKALVTIPETTFQTVSWHFCIALGY 328

Query: 339 LNSCCNPWIYMFFSGHLLQDCVQSF--PCCQNMKEK 372
            NSC NP +Y F   +  + C + F  P   N++++
Sbjct: 329 TNSCLNPVLYAFLDEN-FKRCFREFCIPTSSNIEQQ 363


>gi|167000885 galanin receptor 1 [Homo sapiens]
          Length = 349

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 89/347 (25%), Positives = 144/347 (41%), Gaps = 48/347 (13%)

Query: 55  IAVLAVTFAVAVLGNSSVLLALHRT----PRKTSRMHLFIRHLSLADLAVAFFQVLPQMC 110
           + V  + FA+ VLGNS V+  L R+    PR T+  +LFI +LS+ADLA   F +  Q  
Sbjct: 37  LVVFGLIFALGVLGNSLVITVLARSKPGKPRSTT--NLFILNLSIADLAYLLFCIPFQAT 94

Query: 111 WDITYRFRGPDW-----LCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPAR 165
                 +  P W     +C+ + +     M  S + L  M+ DRY+A+ H  ++      
Sbjct: 95  V-----YALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVS 149

Query: 166 RSRLM-IAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGI 224
           R+ L+ +   W LS  +++P  +   +      +    CW  +  P   +AYV       
Sbjct: 150 RNALLGVGCIWALSIAMASPVAYHQGLFH-PRASNQTFCWEQWPDPRHKKAYVVCTFVFG 208

Query: 225 FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISR 284
           ++ P++++  CY  +      N   K     SK +E                        
Sbjct: 209 YLLPLLLICFCYAKV-----LNHLHKKLKNMSKKSE-----------------------A 240

Query: 285 AKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCN 344
           +K +T +   V+V  + + W P  II +W+ +    +   S    IT   L  S NS  N
Sbjct: 241 SKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYS-NSSVN 299

Query: 345 PWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNN 391
           P IY F S +  +   Q F  C   K+    +  +S SR  T  S N
Sbjct: 300 PIIYAFLSENFRKAYKQVFK-CHIRKDSHLSDTKESKSRIDTPPSTN 345


>gi|4557857 somatostatin receptor 1 [Homo sapiens]
          Length = 391

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 92/370 (24%), Positives = 170/370 (45%), Gaps = 70/370 (18%)

Query: 6   GPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNG---PPRDV-RNEELAKLEIAVLAVT 61
           G  + PS + SP  P + G G  SR   A G  +G   P R+  +N  L++ + + + ++
Sbjct: 5   GTASSPSSSPSPS-PGSCGEGGGSRGPGA-GAADGMEEPGRNASQNGTLSEGQGSAILIS 62

Query: 62  FAVAVL------GNSSVLLALHRTPRKTSRMHLFIRHLSLAD----LAVAFFQVLPQMCW 111
           F  +V+      GNS V+  + R  +  +  +++I +L++AD    L+V F      +  
Sbjct: 63  FIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFL-----VTS 117

Query: 112 DITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLM 170
            +   +     LCR+V  +    MF S Y L V++ DRY+AV HP+K  + +    ++++
Sbjct: 118 TLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVV 177

Query: 171 IAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGI------ 224
               WVLS ++  P   VFS    N+           + P  ++    W+ G +      
Sbjct: 178 NLGVWVLSLLVILP-IVVFSRTAANSDGTVA---CNMLMPEPAQ---RWLVGFVLYTFLM 230

Query: 225 -FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSIS 283
            F+ PV  +  CY  I                   A+   VA + G+         +   
Sbjct: 231 GFLLPVGAICLCYVLII------------------AKMRMVALKAGW---------QQRK 263

Query: 284 RAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTIT-ITALLGSLNSC 342
           R++ +   M  ++V  +++CW PF+++Q+      ++V+ E ++ T++ ++ +LG  NSC
Sbjct: 264 RSERKITLMVMMVVMVFVICWMPFYVVQL------VNVFAEQDDATVSQLSVILGYANSC 317

Query: 343 CNPWIYMFFS 352
            NP +Y F S
Sbjct: 318 ANPILYGFLS 327


>gi|4557865 somatostatin receptor 5 [Homo sapiens]
          Length = 364

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 98/375 (26%), Positives = 159/375 (42%), Gaps = 48/375 (12%)

Query: 17  PWWPLATGAGNTSREAEALGEGNGP----PRDVRNEELAKLEIAVLAVTFAVAVLGNSSV 72
           P +P +T + N S    A G G+      P          + +  L V  A  + GN+ V
Sbjct: 3   PLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVC-AAGLGGNTLV 61

Query: 73  LLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFR--GPDWLCRVVKHL 130
           +  + R  +  +  +++I +L++AD  V +   LP +       F   GP  LCR+V  L
Sbjct: 62  IYVVLRFAKMKTVTNIYILNLAVAD--VLYMLGLPFLATQNAASFWPFGPV-LCRLVMTL 118

Query: 131 QVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QPARRSRLMIAAAWVLSFVLSTPQYFVF 189
                F S + L VM+ DRY+AV HPL + + +  R ++L  AAAWVLS  +S P   VF
Sbjct: 119 DGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLP-LLVF 177

Query: 190 SMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRG 249
           + ++      A   W   +  WG+  ++ +     F AP++++  CY  I   +      
Sbjct: 178 ADVQEGGTCNA--SWPEPVGLWGA-VFIIYTAVLGFFAPLLVICLCYLLIVVKV------ 228

Query: 250 KTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFI 309
                       AGV           V  V+  S  K+   +M  V+V  +  CW PFF 
Sbjct: 229 ----------RAAGVR----------VGCVRRRSERKV--TRMVLVVVLVFAGCWLPFFT 266

Query: 310 IQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNM 369
           + + ++   +     S         +L   NSC NP +Y F S +      QSF     +
Sbjct: 267 VNIVNLAVALPQEPASAG-LYFFVVILSYANSCANPVLYGFLSDNFR----QSFQKVLCL 321

Query: 370 KEKFNKEDTDSMSRR 384
           ++    +D D+   R
Sbjct: 322 RKGSGAKDADATEPR 336


>gi|4885057 apelin receptor [Homo sapiens]
          Length = 380

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 92/380 (24%), Positives = 152/380 (40%), Gaps = 57/380 (15%)

Query: 56  AVLAVTFAVAVLGNSSVLLALHRTPRKTSRM-HLFIRHLSLADLAVAFFQVLPQMCWDIT 114
           A+  + F +   GN  VL  + R+ R+  R   +FI  L++ADL   F   LP   W  T
Sbjct: 33  AIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLT--FVVTLP--LW-AT 87

Query: 115 YRFRGPDW-----LCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRS-R 168
           Y +R  DW      C++  +L    M+AS + L  ++ DRY+A+  P+   +   R S  
Sbjct: 88  YTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGA 147

Query: 169 LMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTG-GI--- 224
           +  A  WVL+ +L+ P   + +  ++ N TK + C+  +       +   W  G G+   
Sbjct: 148 VATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ-CYMDYSMVATVSSEWAWEVGLGVSST 206

Query: 225 ---FVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKS 281
              FV P  I+ TCY FI   I     G     + +G                       
Sbjct: 207 TVGFVVPFTIMLTCYFFIAQTI----AGHFRKERIEGL---------------------- 240

Query: 282 ISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESEN----PTITITALLG 337
             R + R + +  V+V  + +CW P+ +++   +   +  W    +            + 
Sbjct: 241 --RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCIS 298

Query: 338 SLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNS 397
            +NSC NP++Y FF     Q C     C Q+   +       S   +   YS+  S    
Sbjct: 299 YVNSCLNPFLYAFFDPRFRQACTSMLCCGQS---RCAGTSHSSSGEKSASYSSGHSQGPG 355

Query: 398 TGMWKDSPKSSKSIKFIPVS 417
             M K   +  +  K IP S
Sbjct: 356 PNMGKGGEQMHE--KSIPYS 373


>gi|4505513 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 80/340 (23%), Positives = 144/340 (42%), Gaps = 57/340 (16%)

Query: 53  LEIAVLAVTFAVAV---LGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQM 109
           L++ ++ +  AV V   LGN  V+  + R  +  +  +++I +L+LAD  V     LP  
Sbjct: 50  LKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL--TLPFQ 107

Query: 110 CWDITYRFRGPDW-----LCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QP 163
             DI   F    W     LC+ V  +  + MF S + L  M+ DRY+A+CHP++ L  + 
Sbjct: 108 GTDILLGF----WPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRT 163

Query: 164 ARRSRLMIAAAWVLSFVLSTPQYFVFS-MIEVNNVTKARDCWATFIQP---WGSRAYVTW 219
           + +++ +  A W L+ V+  P   + S  +E   +    +C      P   WG   +   
Sbjct: 164 SSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEI----ECLVEIPTPQDYWGP-VFAIC 218

Query: 220 MTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSV 279
           +    F+ PV+++  CY  +              R+ +G                 +S  
Sbjct: 219 IFLFSFIVPVLVISVCYSLMI-------------RRLRGVR--------------LLSGS 251

Query: 280 KSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPT--ITITALLG 337
           +   R   R  ++  V+V  ++ CW P   +Q++ +   + V   SE     +     LG
Sbjct: 252 REKDRNLRRITRLVLVVVAVFVGCWTP---VQVFVLAQGLGVQPSSETAVAILRFCTALG 308

Query: 338 SLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKED 377
            +NSC NP +Y F   +  + C + F C   ++      D
Sbjct: 309 YVNSCLNPILYAFLDEN-FKACFRKFCCASALRRDVQVSD 347


>gi|33286424 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 80/340 (23%), Positives = 144/340 (42%), Gaps = 57/340 (16%)

Query: 53  LEIAVLAVTFAVAV---LGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQM 109
           L++ ++ +  AV V   LGN  V+  + R  +  +  +++I +L+LAD  V     LP  
Sbjct: 50  LKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL--TLPFQ 107

Query: 110 CWDITYRFRGPDW-----LCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQ-QP 163
             DI   F    W     LC+ V  +  + MF S + L  M+ DRY+A+CHP++ L  + 
Sbjct: 108 GTDILLGF----WPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRT 163

Query: 164 ARRSRLMIAAAWVLSFVLSTPQYFVFS-MIEVNNVTKARDCWATFIQP---WGSRAYVTW 219
           + +++ +  A W L+ V+  P   + S  +E   +    +C      P   WG   +   
Sbjct: 164 SSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEI----ECLVEIPTPQDYWGP-VFAIC 218

Query: 220 MTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSV 279
           +    F+ PV+++  CY  +              R+ +G                 +S  
Sbjct: 219 IFLFSFIVPVLVISVCYSLMI-------------RRLRGVR--------------LLSGS 251

Query: 280 KSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPT--ITITALLG 337
           +   R   R  ++  V+V  ++ CW P   +Q++ +   + V   SE     +     LG
Sbjct: 252 REKDRNLRRITRLVLVVVAVFVGCWTP---VQVFVLAQGLGVQPSSETAVAILRFCTALG 308

Query: 338 SLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKED 377
            +NSC NP +Y F   +  + C + F C   ++      D
Sbjct: 309 YVNSCLNPILYAFLDEN-FKACFRKFCCASALRRDVQVSD 347


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.134    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,673,841
Number of Sequences: 37866
Number of extensions: 670291
Number of successful extensions: 3882
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 425
Number of HSP's successfully gapped in prelim test: 315
Number of HSP's that attempted gapping in prelim test: 2499
Number of HSP's gapped (non-prelim): 971
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press