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Search of human proteins with 4502053
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo
sapiens]
(701 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens] 1460 0.0
gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens] 808 0.0
gi|85067501 arachidonate 15-lipoxygenase, second type isoform d ... 694 0.0
gi|85067499 arachidonate 15-lipoxygenase, second type isoform a ... 651 0.0
gi|85067503 arachidonate 15-lipoxygenase, second type isoform b ... 578 e-165
gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens] 536 e-152
gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens] 464 e-131
gi|40316937 arachidonate 15-lipoxygenase [Homo sapiens] 423 e-118
gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap... 44 5e-04
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 44 5e-04
gi|5174633 receptor for egg jelly-like protein precursor [Homo s... 34 0.40
gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sap... 33 0.69
gi|150010661 SEC14-like 5 [Homo sapiens] 30 5.8
gi|115298672 neutrophil cytosolic factor 1 [Homo sapiens] 30 7.6
gi|197333811 URB2 ribosome biogenesis 2 homolog [Homo sapiens] 30 7.6
gi|188497630 hypothetical protein LOC55571 [Homo sapiens] 30 7.6
gi|4557727 lipoprotein lipase precursor [Homo sapiens] 30 9.9
gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens] 30 9.9
gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo ... 30 9.9
gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo ... 30 9.9
>gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens]
Length = 701
Score = 1460 bits (3780), Expect = 0.0
Identities = 701/701 (100%), Positives = 701/701 (100%)
Query: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD 60
MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD
Sbjct: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD 60
Query: 61 LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALREATGKT 120
LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALREATGKT
Sbjct: 61 LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALREATGKT 120
Query: 121 TADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEWNGY 180
TADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEWNGY
Sbjct: 121 TADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEWNGY 180
Query: 181 IPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKRLKDIR 240
IPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKRLKDIR
Sbjct: 181 IPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKRLKDIR 240
Query: 241 KIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVAPFLGE 300
KIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVAPFLGE
Sbjct: 241 KIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVAPFLGE 300
Query: 301 GTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGKMMPIAIQLSQ 360
GTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGKMMPIAIQLSQ
Sbjct: 301 GTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGKMMPIAIQLSQ 360
Query: 361 TPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALLRNLPMC 420
TPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALLRNLPMC
Sbjct: 361 TPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALLRNLPMC 420
Query: 421 HPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSELTYDSLY 480
HPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSELTYDSLY
Sbjct: 421 HPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSELTYDSLY 480
Query: 481 LPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQSWVQEI 540
LPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQSWVQEI
Sbjct: 481 LPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQSWVQEI 540
Query: 541 FKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPNFPASMR 600
FKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPNFPASMR
Sbjct: 541 FKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPNFPASMR 600
Query: 601 NPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFVEEAPRR 660
NPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFVEEAPRR
Sbjct: 601 NPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFVEEAPRR 660
Query: 661 SIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701
SIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI
Sbjct: 661 SIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701
>gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens]
Length = 711
Score = 808 bits (2086), Expect = 0.0
Identities = 385/711 (54%), Positives = 508/711 (71%), Gaps = 10/711 (1%)
Query: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD 60
MA Y++ V TG L +GT D+IS+T+VGT GES KQ L+ GRDFA G+V +Y V+C +
Sbjct: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE 60
Query: 61 LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALREATGKT 120
LGEL+++R+HKERYAFF KD WYC+ + + P+G + HFP YQW++GY T+ LR T +T
Sbjct: 61 LGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRPGTART 120
Query: 121 TADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHR---------- 170
DSLP+LL+HR E+RA+Q+ Y W+++ PG P V + S++ +
Sbjct: 121 ICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTKTTTCV 180
Query: 171 NPNRPEWNGYIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCK 230
+ N Y+PGFP+ I+ + ++ N+RYS KT S P +L K+RGLLD K
Sbjct: 181 DQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRGLLDRK 240
Query: 231 HSWKRLKDIRKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVT 290
SWK+L D++ IF K+ ++YV EHW ED FFGYQYLNGVNP ++ + +P K PVT
Sbjct: 241 GSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPSKLPVT 300
Query: 291 DDMVAPFLGEGTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGK 350
+DMVAP LG+ TCLQ ELE+GNI+LADY I+ PT L+GR+Q+ APLCLL P+G
Sbjct: 301 NDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWLSPQGA 360
Query: 351 MMPIAIQLSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFC 410
++P+AIQLSQTPGPD PIFLP+DSEWDWLLAKTWVR +EF HE H L THL+ EAF
Sbjct: 361 LVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHLLCEAFA 420
Query: 411 LALLRNLPMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRA 470
+A LR LP+CHP+YKLL+PHTRYT+Q+N+I RA LLN GL + S+G +G +M
Sbjct: 421 MATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLIYLMSTG 480
Query: 471 LSELTYDSLYLPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGD 530
L+ TY + LP+ RGV +P Y+YRDD L +W A+E +V+EI+ YYYPSDA+V+ D
Sbjct: 481 LAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSDASVQQD 540
Query: 531 PELQSWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTA 590
ELQ+W EIF + LGRESSGFP L T E+++++T +I+ CSA+HAAVN+GQ +F A
Sbjct: 541 SELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSGQHDFGA 600
Query: 591 WMPNFPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPD 650
WMPN P+SMR PP QTKG TTL+T++DTLP+V +C LL+ W +S+EP D+RPLG +PD
Sbjct: 601 WMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRPLGTYPD 660
Query: 651 IHFVEEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701
HF EEAPRRSI AF+ RL QIS DI++RN+ L +PY YLDP LIENS+SI
Sbjct: 661 EHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711
>gi|85067501 arachidonate 15-lipoxygenase, second type isoform d
[Homo sapiens]
Length = 676
Score = 694 bits (1792), Expect = 0.0
Identities = 342/707 (48%), Positives = 468/707 (66%), Gaps = 37/707 (5%)
Query: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD 60
MA ++VRV+TG +GT D +S++IVGT+GES L++ G++F GA + V P+D
Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
Query: 61 LGELIIIRLHKERYAF-----FPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALRE 115
+G ++++R+HK D W+C + Q+ P G FP YQW++G TL L+E
Sbjct: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120
Query: 116 ATGKTTADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRP 175
T K + D PVL + R+EE++A+Q+ Y W+
Sbjct: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKA--------------------------- 153
Query: 176 EWNGYIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKR 235
Y PG+P ++ K + L LN++YS K A+F+++ G K++GLLD K W+
Sbjct: 154 ----YNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRS 209
Query: 236 LKDIRKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVA 295
L ++++IF +++ +E+ EHW ED FF Q+LNG+NP LIRRC +P FPVTD MVA
Sbjct: 210 LNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVA 269
Query: 296 PFLGEGTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPE-GKMMPI 354
LG GT LQAELEKG+++L D+ I+ GI T ++G+ Q AP+ LL+ P G ++P+
Sbjct: 270 SVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPL 329
Query: 355 AIQLSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALL 414
AIQLSQTPGP+ PIFLP+D +WDWLLAKTWVR AEF HEA+ HLL +HL+ E F LA L
Sbjct: 330 AIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATL 389
Query: 415 RNLPMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSEL 474
R LP CHPL+KLLIPHTRYT+ IN++ R +L+ G + + +G+EGF+ ++ R + +L
Sbjct: 390 RQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQL 449
Query: 475 TYDSLYLPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQ 534
Y L LP D RGV+D+PGYYYRDD + +W A+E++V+EII YYPSD +V+ D ELQ
Sbjct: 450 NYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQ 509
Query: 535 SWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPN 594
+WV+EIF + L +ESSG P L T L++YVT+VI+TCSAKHAAV+ GQ + AWMPN
Sbjct: 510 AWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPN 569
Query: 595 FPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFV 654
P SM+ PP +KGL T E F+ TLP V TC +L LW LS+EP D+RPLG +PD HF
Sbjct: 570 LPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFT 629
Query: 655 EEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701
EEAPRRSI F+ RL QIS I++RN+ L +PY YLDP LIENS+SI
Sbjct: 630 EEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 676
>gi|85067499 arachidonate 15-lipoxygenase, second type isoform a
[Homo sapiens]
Length = 647
Score = 651 bits (1679), Expect = 0.0
Identities = 328/707 (46%), Positives = 447/707 (63%), Gaps = 66/707 (9%)
Query: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD 60
MA ++VRV+TG +GT D +S++IVGT+GES L++ G++F GA + V P+D
Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
Query: 61 LGELIIIRLHKERYAF-----FPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALRE 115
+G ++++R+HK D W+C + Q+ P G FP YQW++G TL L+E
Sbjct: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120
Query: 116 ATGKTTADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRP 175
T K + D PVL + R+EE++A+Q+ Y W+
Sbjct: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKA--------------------------- 153
Query: 176 EWNGYIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKR 235
Y PG+P ++ K + L LN++YS K A+F+++ G K++GLLD K W+
Sbjct: 154 ----YNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRS 209
Query: 236 LKDIRKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVA 295
L ++++IF +++ +E+ EHW ED FF Q+LNG+NP LIRRC +P FPVTD MVA
Sbjct: 210 LNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVA 269
Query: 296 PFLGEGTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPE-GKMMPI 354
LG GT LQAELEKG+++L D+ I+ GI T ++G+ Q AP+ LL+ P G ++P+
Sbjct: 270 SVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPL 329
Query: 355 AIQLSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALL 414
AIQLSQTPGP+ PIFLP+D +WDWLLAKTWVR AEF HEA+ HLL +HL+ E F LA L
Sbjct: 330 AIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATL 389
Query: 415 RNLPMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSEL 474
R LP CHPL+K +G+EGF+ ++ R + +L
Sbjct: 390 RQLPHCHPLFK-----------------------------STGIGIEGFSELIQRNMKQL 420
Query: 475 TYDSLYLPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQ 534
Y L LP D RGV+D+PGYYYRDD + +W A+E++V+EII YYPSD +V+ D ELQ
Sbjct: 421 NYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQ 480
Query: 535 SWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPN 594
+WV+EIF + L +ESSG P L T L++YVT+VI+TCSAKHAAV+ GQ + AWMPN
Sbjct: 481 AWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPN 540
Query: 595 FPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFV 654
P SM+ PP +KGL T E F+ TLP V TC +L LW LS+EP D+RPLG +PD HF
Sbjct: 541 LPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFT 600
Query: 655 EEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701
EEAPRRSI F+ RL QIS I++RN+ L +PY YLDP LIENS+SI
Sbjct: 601 EEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 647
>gi|85067503 arachidonate 15-lipoxygenase, second type isoform b
[Homo sapiens]
Length = 602
Score = 578 bits (1491), Expect = e-165
Identities = 303/707 (42%), Positives = 412/707 (58%), Gaps = 111/707 (15%)
Query: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD 60
MA ++VRV+TG +GT D +S++IVGT+GES L++ G++F GA + V P+D
Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
Query: 61 LGELIIIRLHKERYAF-----FPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALRE 115
+G ++++R+HK D W+C + Q+ P G FP YQW++G TL L+E
Sbjct: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120
Query: 116 ATGKTTADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRP 175
T K + D PVL + R+EE++A+Q+ Y W+
Sbjct: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKA--------------------------- 153
Query: 176 EWNGYIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKR 235
Y PG+P ++ K + L LN++YS K A+F+++ G K++GLLD K W+
Sbjct: 154 ----YNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRS 209
Query: 236 LKDIRKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVA 295
L ++++IF +++ +E+ EHW ED FF Q+LNG+NP LIRRC +P FPVTD MVA
Sbjct: 210 LNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVA 269
Query: 296 PFLGEGTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPE-GKMMPI 354
LG GT LQAELEKG+++L D+ I+ GI T ++G+ Q AP+ LL+ P G ++P+
Sbjct: 270 SVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPL 329
Query: 355 AIQLSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALL 414
AIQLSQTPGP+ PIFLP+D +WDWLLAKTWVR AEF HEA+ HLL +HL+ E F LA L
Sbjct: 330 AIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATL 389
Query: 415 RNLPMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSEL 474
R LP CHPL+K +G+EGF+ ++ R + +L
Sbjct: 390 RQLPHCHPLFK-----------------------------STGIGIEGFSELIQRNMKQL 420
Query: 475 TYDSLYLPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQ 534
Y L LP D RGV+D+PGYYYRDD + +W
Sbjct: 421 NYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIW---------------------------- 452
Query: 535 SWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPN 594
G P L T L++YVT+VI+TCSAKHAAV+ GQ + AWMPN
Sbjct: 453 -----------------GIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPN 495
Query: 595 FPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFV 654
P SM+ PP +KGL T E F+ TLP V TC +L LW LS+EP D+RPLG +PD HF
Sbjct: 496 LPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFT 555
Query: 655 EEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701
EEAPRRSI F+ RL QIS I++RN+ L +PY YLDP LIENS+SI
Sbjct: 556 EEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 602
>gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens]
Length = 674
Score = 536 bits (1381), Expect = e-152
Identities = 282/707 (39%), Positives = 414/707 (58%), Gaps = 39/707 (5%)
Query: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNH-FGRDFATGAVGQYTVQCPQ 59
M +Y V VATG+ +GT D I L++VG+ G S K LL+ F DF GAV Y V +
Sbjct: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
Query: 60 DLGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALREATGK 119
+LGE+ ++R+ K +Y + D WY Y+ + P+G FP Y+W+ G + LR+ K
Sbjct: 61 ELGEIQLVRIEKRKY--WLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAK 118
Query: 120 TTADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEWNG 179
DD + +L +HR++E+ +Q Y W EWN
Sbjct: 119 LARDDQIHILKQHRRKELETRQKQYRWM----------------------------EWN- 149
Query: 180 YIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLG-PMALAFKVRGLLDCKHSWKRLKD 238
PGFP+ I+ K K L ++++ K F + M F R + + SW D
Sbjct: 150 --PGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFAD 207
Query: 239 IRKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVAPFL 298
KIF + +SE V HW ED FGYQ+LNG NP LIRRCT +P+K PVT +MV L
Sbjct: 208 FEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSL 267
Query: 299 GEGTCLQAELEKGNIYLADYRIMEGIPTVELSG-RKQHHCAPLCLLHFGPEGKMMPIAIQ 357
L+ E+++GNI++ D+ +++GI + Q AP+CLL+ K++PIAIQ
Sbjct: 268 ERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQ 327
Query: 358 LSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALLRNL 417
L+Q PG + PIFLPSD+++DWLLAK WVR ++F+ H+ I HLL THL++E F +A+ R L
Sbjct: 328 LNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQL 387
Query: 418 PMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSELTYD 477
P HP++KLL+ H R+T+ IN+ R L+ E GL K + G G ++ RA+ +LTY
Sbjct: 388 PAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYA 447
Query: 478 SLYLPNDFVERGV---QDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQ 534
SL P RG+ +D+P Y+YRDD L VW A+ + E++ YY D VE DPELQ
Sbjct: 448 SLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQ 507
Query: 535 SWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPN 594
+V +++ + GR+SSGFP+ +++ +L Y+T+VI+T SA+HAAVN GQ ++ +W+PN
Sbjct: 508 DFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPN 567
Query: 595 FPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFV 654
P +MR PP KG+ T+E +DTLPD +C L +W LS+ ++ LG +P+ HF+
Sbjct: 568 APPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFI 627
Query: 655 EEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701
E+ + ++ FR+ L I I +RNK +PYYYL P I NS++I
Sbjct: 628 EKPVKEAMARFRKNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI 674
>gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens]
Length = 663
Score = 464 bits (1195), Expect = e-131
Identities = 258/709 (36%), Positives = 391/709 (55%), Gaps = 54/709 (7%)
Query: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD 60
M Y++RVATG L SG+ + + L +VGT+GE+ +L R G ++ +D
Sbjct: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPAR----GEEEEFDHDVAED 56
Query: 61 LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRI-YHFPAYQWMDGYETLALREATGK 119
LG L +RL K + D W+C+ + + P FP Y+W+ G + L+L E T +
Sbjct: 57 LGLLQFVRLRKHHWLV--DDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTAR 114
Query: 120 TTADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEWNG 179
D++L + +HR++E++ +Q Y W + GLP + R + P
Sbjct: 115 LPGDNALDMFQKHREKELKDRQQIYCWATWKEGLPL---------TIAADRKDDLPP--- 162
Query: 180 YIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKRLKDI 239
N+R+ K F L AL ++ + SW L+D
Sbjct: 163 -------------------NMRFHEEKRLDFEWTLKAGALEMALKRVYTLLSSWNCLEDF 203
Query: 240 RKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVAPFLG 299
+IF G+KS ++E V + W +D F YQ+LNG NP L+RR T +P + + M
Sbjct: 204 DQIFWGQKSALAEKVRQCWQDDELFSYQFLNGANPMLLRRSTSLPSRLVLPSGMEE---- 259
Query: 300 EGTCLQAELEK----GNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGKMMPIA 355
LQA+LEK G+++ AD+ +++GIP + G KQ+ APL +L P GK+ P+
Sbjct: 260 ----LQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPLVMLKMEPNGKLQPMV 315
Query: 356 IQLSQTPGPDCP---IFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLA 412
IQ+ Q P P P +FLPSD WLLAK+WVR ++F HE HLL THL+AE +A
Sbjct: 316 IQI-QPPNPSSPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHEIQYHLLNTHLVAEVIAVA 374
Query: 413 LLRNLPMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALS 472
+R LP HP++K LIPH RYT++IN+ R L+++GG+ K +S G G ++ RA +
Sbjct: 375 TMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLISDGGIFDKAVSTGGGGHVQLLRRAAA 434
Query: 473 ELTYDSLYLPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPE 532
+LTY SL P+D +RG+ LPG Y D+L +W + +YV I+ +Y D V+GDPE
Sbjct: 435 QLTYCSLCPPDDLADRGLLGLPGALYAHDALRLWEIIARYVEGIVHLFYQRDDIVKGDPE 494
Query: 533 LQSWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWM 592
LQ+W +EI + L + GFP ++ +L ++T+ ++TC+A+HAA+N GQ+++ AW+
Sbjct: 495 LQAWCREITEVGLCQAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQHAAINQGQLDWYAWV 554
Query: 593 PNFPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIH 652
PN P +MR PP TK T+ T M +LPDV+ C+ + + W LSR D PLGH + +
Sbjct: 555 PNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISWHLSRRQPDMVPLGHHKEKY 614
Query: 653 FVEEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701
F P+ + FR L ++ +I RN+ L PY YL P IENS++I
Sbjct: 615 FSGPKPKAVLNQFRTDLEKLEKEITARNEQLDWPYEYLKPSCIENSVTI 663
>gi|40316937 arachidonate 15-lipoxygenase [Homo sapiens]
Length = 662
Score = 423 bits (1088), Expect = e-118
Identities = 239/711 (33%), Positives = 381/711 (53%), Gaps = 59/711 (8%)
Query: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDF--ATGAVGQYTVQCP 58
M Y++RV+TG L +G+ + + L +VG GE+ G+ A G + V+ P
Sbjct: 1 MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAA------LGKRLWPARGKETELKVEVP 54
Query: 59 QDLGELIIIRLHKERYAFFPKDPWYCNYVQICAPN-GRIYHFPAYQWMDGYETLALREAT 117
+ LG L+ ++L K D W+CN++ + P G FP Y+W++G L+L E T
Sbjct: 55 EYLGPLLFVKLRKRH--LLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLSLPEGT 112
Query: 118 GKTTADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEW 177
G+T +D + +HR+EE+ ++ Y W + GL
Sbjct: 113 GRTVGEDPQGLFQKHREEELEERRKLYRWGNWKDGL------------------------ 148
Query: 178 NGYIPGFPILINFKATKFLNLNLRYSFL--KTASFFVRLGPMALAFKVRGLLDCKHSWKR 235
++N K +L + FL K F V L ++ L+ WK
Sbjct: 149 ---------ILNMAGAKLYDLPVDERFLEDKRVDFEVSLAKGLADLAIKDSLNVLTCWKD 199
Query: 236 LKDIRKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKF---PVTDD 292
L D +IF +S ++E V + W ED FGYQ+LNG NP ++RR +P + P ++
Sbjct: 200 LDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPVVLRRSAHLPARLVFPPGMEE 259
Query: 293 MVAPFLGEGTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGKMM 352
+ A L+ ELE G ++ AD+ +++GI + +QH APL +L P+GK++
Sbjct: 260 LQAQ-------LEKELEGGTLFEADFSLLDGIKANVILCSQQHLAAPLVMLKLQPDGKLL 312
Query: 353 PIAIQLS--QTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFC 410
P+ IQL +T P P+FLP+D WLLAK WVR ++F HE +HLL HL+AE
Sbjct: 313 PMVIQLQLPRTGSPPPPLFLPTDPPMAWLLAKCWVRSSDFQLHELQSHLLRGHLMAEVIV 372
Query: 411 LALLRNLPMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRA 470
+A +R LP HP++KL+IPH RYT++IN R L+++ G+ + MS G G ++ +A
Sbjct: 373 VATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGIFDQIMSTGGGGHVQLLKQA 432
Query: 471 LSELTYDSLYLPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGD 530
+ LTY S P+D +RG+ + +Y D+L +W + +YV I++ +Y +D AV+ D
Sbjct: 433 GAFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIYRYVEGIVSLHYKTDVAVKDD 492
Query: 531 PELQSWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTA 590
PELQ+W +EI + L G + GFP L+ ++ +VT+ I+TC+ +HA+V+ GQ+++ +
Sbjct: 493 PELQTWCREITEIGLQGAQDRGFPVSLQARDQVCHFVTMCIFTCTGQHASVHLGQLDWYS 552
Query: 591 WMPNFPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPD 650
W+PN P +MR PP TK TLET M TLP+ + + + W L R +G +
Sbjct: 553 WVPNAPCTMRLPPPTTKD-ATLETVMATLPNFHQASLQMSITWQLGRRQPVMVAVGQHEE 611
Query: 651 IHFVEEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701
+F P+ ++ FR+ L + +I RN L +PY YL P ++ENS++I
Sbjct: 612 EYFSGPEPKAVLKKFREELAALDKEIEIRNAKLDMPYEYLRPSVVENSVAI 662
>gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo
sapiens]
Length = 1114
Score = 43.9 bits (102), Expect = 5e-04
Identities = 30/107 (28%), Positives = 56/107 (52%), Gaps = 7/107 (6%)
Query: 3 TYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRD---FATGAVGQYTVQCPQ 59
T+ V + TG +GT ++ +T+ GTQ ++ LL + F ++ +TV+
Sbjct: 65 TFSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVE-TL 123
Query: 60 DLGELIIIRLHKERYAFFPKDPWYCNYVQICAPN-GRIYHFPAYQWM 105
DLG+L +RL + P W+ ++V++ AP+ G+ FP +W+
Sbjct: 124 DLGDLWKVRLGHDNTGKAP--GWFVDWVEVDAPSLGKCMTFPCGRWL 168
Score = 32.0 bits (71), Expect = 2.0
Identities = 32/125 (25%), Positives = 48/125 (38%), Gaps = 13/125 (10%)
Query: 3 TYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFG--RDFATGAVGQYTVQCPQD 60
+Y V V T L +GT ++ + I G G+S L F +
Sbjct: 775 SYTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLS 834
Query: 61 LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGR--IYHFPAYQWMDGYETLALREATG 118
LG L +R+ + FP W+ +YV + N R +HF W L+ E G
Sbjct: 835 LGHLCKLRVWHDNKGIFP--GWHLSYVDV-KDNSRDETFHFQCDCW------LSKSEGDG 885
Query: 119 KTTAD 123
+T D
Sbjct: 886 QTVRD 890
>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens]
Length = 2211
Score = 43.9 bits (102), Expect = 5e-04
Identities = 30/107 (28%), Positives = 56/107 (52%), Gaps = 7/107 (6%)
Query: 3 TYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRD---FATGAVGQYTVQCPQ 59
T+ V + TG +GT ++ +T+ GTQ ++ LL + F ++ +TV+
Sbjct: 1176 TFSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVE-TL 1234
Query: 60 DLGELIIIRLHKERYAFFPKDPWYCNYVQICAPN-GRIYHFPAYQWM 105
DLG+L +RL + P W+ ++V++ AP+ G+ FP +W+
Sbjct: 1235 DLGDLWKVRLGHDNTGKAP--GWFVDWVEVDAPSLGKCMTFPCGRWL 1279
Score = 43.1 bits (100), Expect = 9e-04
Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 12/122 (9%)
Query: 4 YKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQDLGE 63
Y+V+V TG + +GT + + I G G++ ++ L + +F GA ++ + P DLG+
Sbjct: 174 YEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRLENEKDNFEKGAEDRFILDAP-DLGQ 232
Query: 64 LIIIRL-HKERYAFFPKDPWYCNYVQI-CAPNGRIYHFPAYQWMDGYETLALREATGKTT 121
L+ I + H + W+ + + I N R Y FP +W LAL E GK
Sbjct: 233 LMKINVGHNNKGG---SAGWFLSQIVIEDIGNKRKYDFPLNRW------LALDEDDGKIQ 283
Query: 122 AD 123
D
Sbjct: 284 RD 285
Score = 41.2 bits (95), Expect = 0.003
Identities = 38/130 (29%), Positives = 63/130 (48%), Gaps = 14/130 (10%)
Query: 3 TYKVRVATGTDLLSGTRDSISLTIVGTQ-GESHKQLLNHFGRD--FATGAVGQYTVQCPQ 59
TY+V+V TG +GT ++ LTI G + G++ ++ L + F G +T+
Sbjct: 1023 TYEVQVVTGNVPKAGTDANVYLTIYGEEYGDTGERPLKKSDKSNKFEQGQTDTFTIYA-I 1081
Query: 60 DLGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRI-YHFPAYQWMDGYETLALREATG 118
DLG L IR+ + + W+ + + I N I Y+FP +W LA+ E G
Sbjct: 1082 DLGALTKIRIRHDNTG--NRAGWFLDRIDITDMNNEITYYFPCQRW------LAVEEDDG 1133
Query: 119 KTTADDSLPV 128
+ + + LPV
Sbjct: 1134 QLSR-ELLPV 1142
Score = 35.4 bits (80), Expect = 0.18
Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 12/110 (10%)
Query: 4 YKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLL----NHFGRDFATGAVGQYTVQCPQ 59
Y + + TG + T + + + G + ++ KQ+L N+ F G V ++T++
Sbjct: 686 YHISLKTGDVSGASTDSRVYIKLYGDKSDTIKQVLLVSDNNLKDYFERGRVDEFTLETLN 745
Query: 60 --DLGELIIIRLHKERYAFFPKDPWYCNYVQICAPN-GRIYHFPAYQWMD 106
++ L+I +A W+ VQI P G+ Y FPA +W+D
Sbjct: 746 IGNINRLVIGHDSTGMHA-----SWFLGSVQIRVPRQGKQYTFPANRWLD 790
Score = 35.0 bits (79), Expect = 0.24
Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 5/100 (5%)
Query: 12 TDLL-SGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQDLGELIIIRLH 70
TDL +GT I + I G +G + + LLN + F G + ++ ++ P DLG IR+
Sbjct: 434 TDLKKAGTNSPIFIQIYGQKGRTDEILLNPNNKWFKPGIIEKFRIELP-DLGRFYKIRVW 492
Query: 71 KERYAFFPKDPWYCNYVQIC-APNGRIYHFPAYQWMDGYE 109
++ + W+ + + N Y+F +W+D E
Sbjct: 493 HDKRS--SGSGWHLERMTLMNTLNKDKYNFNCNRWLDANE 530
Score = 33.5 bits (75), Expect = 0.69
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 5/105 (4%)
Query: 4 YKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRD-FATGAVGQYTVQCPQDLG 62
Y+V V TG + +GT ++ +TI G G++ K+ L R+ F G+ ++ ++ +LG
Sbjct: 2094 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLE-TLELG 2152
Query: 63 ELIIIRLHKERYAFFPKDPWYCNYVQIC-APNGRIYHFPAYQWMD 106
EL +RL + + W V++ G F +W+D
Sbjct: 2153 ELRKVRLEHDSSGYC--SGWLVEKVEVTNTSTGVATIFNCGRWLD 2195
Score = 32.0 bits (71), Expect = 2.0
Identities = 32/125 (25%), Positives = 48/125 (38%), Gaps = 13/125 (10%)
Query: 3 TYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFG--RDFATGAVGQYTVQCPQD 60
+Y V V T L +GT ++ + I G G+S L F +
Sbjct: 1824 SYTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLS 1883
Query: 61 LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGR--IYHFPAYQWMDGYETLALREATG 118
LG L +R+ + FP W+ +YV + N R +HF W L+ E G
Sbjct: 1884 LGHLCKLRVWHDNKGIFP--GWHLSYVDV-KDNSRDETFHFQCDCW------LSKSEGDG 1934
Query: 119 KTTAD 123
+T D
Sbjct: 1935 QTVRD 1939
Score = 31.6 bits (70), Expect = 2.6
Identities = 27/105 (25%), Positives = 40/105 (38%), Gaps = 3/105 (2%)
Query: 3 TYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQDLG 62
TY V V TG +GT+ I L + G +G + + G F G + ++ L
Sbjct: 297 TYIVTVFTGDVRGAGTKSKIYLVMYGARGNKNSGKIFLEGGVFDRGRTDIFHIELAVLLS 356
Query: 63 ELIIIRLHKERYAFFPKDPWYCNYVQICAP-NGRIYHFPAYQWMD 106
L + + W+C V I P G FP W+D
Sbjct: 357 PLSRVSVGHGNVGV--NRGWFCEKVVILCPFTGIQQTFPCSNWLD 399
Score = 30.0 bits (66), Expect = 7.6
Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
Query: 4 YKVRVATGTDLLSGTRDSISLTIVGTQGESHK-QLLNHFGRDFATGAVGQYTVQCPQDLG 62
Y+V ATG +GT ++ +T+ G G S K QL + F G V + V+ ++G
Sbjct: 45 YEVVTATGDVRGAGTDANVFITLFGENGLSPKLQLTSKSKSAFEKGNVDVFRVR-TNNVG 103
Query: 63 ELIIIRLHKERYAFFPKDPWYCNYVQIC---APNGRIYHFPAYQWMDGYE 109
+ +R+ + WY ++V + P+ R Y+F W+ E
Sbjct: 104 LIYKVRIEHDNTGL--NASWYLDHVIVTDMKRPHLR-YYFNCNNWLSKVE 150
>gi|5174633 receptor for egg jelly-like protein precursor [Homo
sapiens]
Length = 2253
Score = 34.3 bits (77), Expect = 0.40
Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 8/112 (7%)
Query: 4 YKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFAT---GAVGQYTVQCPQD 60
Y V + TG+ SGTR ++ + + GT S L+H F T G++ + + D
Sbjct: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSH--PHFTTLYRGSINTFLLTTKSD 1289
Query: 61 LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGR-IYHFPAYQWMDGYETL 111
LG++ IR+ P WY + +++ R I+ F +W+ TL
Sbjct: 1290 LGDIHSIRVWHNNEGRSPS--WYLSRIKVENLFSRHIWLFICQKWLSVDTTL 1339
>gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo
sapiens]
Length = 512
Score = 33.5 bits (75), Expect = 0.69
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 5/105 (4%)
Query: 4 YKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRD-FATGAVGQYTVQCPQDLG 62
Y+V V TG + +GT ++ +TI G G++ K+ L R+ F G+ ++ ++ +LG
Sbjct: 395 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLE-TLELG 453
Query: 63 ELIIIRLHKERYAFFPKDPWYCNYVQIC-APNGRIYHFPAYQWMD 106
EL +RL + + W V++ G F +W+D
Sbjct: 454 ELRKVRLEHDSSGYC--SGWLVEKVEVTNTSTGVATIFNCGRWLD 496
Score = 32.0 bits (71), Expect = 2.0
Identities = 32/125 (25%), Positives = 48/125 (38%), Gaps = 13/125 (10%)
Query: 3 TYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFG--RDFATGAVGQYTVQCPQD 60
+Y V V T L +GT ++ + I G G+S L F +
Sbjct: 125 SYTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLS 184
Query: 61 LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGR--IYHFPAYQWMDGYETLALREATG 118
LG L +R+ + FP W+ +YV + N R +HF W L+ E G
Sbjct: 185 LGHLCKLRVWHDNKGIFP--GWHLSYVDV-KDNSRDETFHFQCDCW------LSKSEGDG 235
Query: 119 KTTAD 123
+T D
Sbjct: 236 QTVRD 240
>gi|150010661 SEC14-like 5 [Homo sapiens]
Length = 696
Score = 30.4 bits (67), Expect = 5.8
Identities = 31/125 (24%), Positives = 49/125 (39%), Gaps = 21/125 (16%)
Query: 282 RIPDKFPVTDDMVAPFLGEGTCLQAELEKGNIY-----LADYRIMEGIPTVELSGRKQHH 336
R P FPV +++PF+ E T + + G+ Y L DY E IP L G
Sbjct: 423 RAPRVFPVLWTLISPFINENTRRKFLIYSGSNYQGPGGLVDYLDREVIPDF-LGGES--- 478
Query: 337 CAPLCLLHFGPEGKMMPIAIQLSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAI 396
+C + PEG ++P ++ +++ +D W W HE
Sbjct: 479 ---VCNV---PEGGLVPKSLYMTEEEQEH------TDQLWQWSETYHSASVLRGAPHEVA 526
Query: 397 AHLLE 401
+LE
Sbjct: 527 VEILE 531
>gi|115298672 neutrophil cytosolic factor 1 [Homo sapiens]
Length = 390
Score = 30.0 bits (66), Expect = 7.6
Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 59 QDLGELIIIRLHKERYAFFP--KDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALREA 116
QDL E ++ R E Y F K+ + I N I H PA +W DG R+
Sbjct: 33 QDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENRQG 92
Query: 117 T 117
T
Sbjct: 93 T 93
>gi|197333811 URB2 ribosome biogenesis 2 homolog [Homo sapiens]
Length = 1524
Score = 30.0 bits (66), Expect = 7.6
Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 10/106 (9%)
Query: 341 CLLHFGPEGKMMPIAIQLSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIA-HL 399
C++ + P+ L TPGP+ ++L S+ LL+ TW + +S H
Sbjct: 570 CMMERMMRELVQPLLALLPDTPGPEPELWLQKVSDSVLLLSYTWAQVDAMFSLNCSQYHS 629
Query: 400 LETHLIAEAFCLALLRNLPMCHPLYKLLIPH----TRYTVQINSIG 441
+ LI A ++ NLP P K H ++T Q +S+G
Sbjct: 630 MSGPLIGVALEIS---NLPSLLPGVK--TQHWKKIEKFTAQFSSLG 670
>gi|188497630 hypothetical protein LOC55571 [Homo sapiens]
Length = 510
Score = 30.0 bits (66), Expect = 7.6
Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 151 PGLPSYVHIPSYRPPVRRHRNPNRPEWNGYIPGFPILINFKATKFLNLNLRYSFLKTAS- 209
P S+ H+ + PP R + P+RP +G++P F ++ + R F KT
Sbjct: 144 PFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPPRELFKKTPRQ 203
Query: 210 -FFVRLGPMALAFKVRGL 226
+ +G M + + GL
Sbjct: 204 IALMDVGNMGQSVDISGL 221
>gi|4557727 lipoprotein lipase precursor [Homo sapiens]
Length = 475
Score = 29.6 bits (65), Expect = 9.9
Identities = 17/81 (20%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 4 YKVRVA-TGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQDLG 62
Y+V++ +GT+ + T + +++ GT ES + + +T + + D+G
Sbjct: 343 YQVKIHFSGTESETHTNQAFEISLYGTVAESEN--IPFTLPEVSTNKTYSFLIYTEVDIG 400
Query: 63 ELIIIRLHKERYAFFPKDPWY 83
EL++++L + ++F W+
Sbjct: 401 ELLMLKLKWKSDSYFSWSDWW 421
>gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens]
Length = 1029
Score = 29.6 bits (65), Expect = 9.9
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 6/106 (5%)
Query: 4 YKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLL--NHFGRDFATGAVGQYTVQCPQDL 61
Y+V VATG +GT ++ ++I G +G++ + L + +F G + ++ L
Sbjct: 43 YEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEAVH-L 101
Query: 62 GELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRI-YHFPAYQWMD 106
G+L I + + P + W+ + V I P Y F ++W+D
Sbjct: 102 GDLCKIVIGHD--GLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLD 145
>gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo
sapiens]
Length = 1029
Score = 29.6 bits (65), Expect = 9.9
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 6/106 (5%)
Query: 4 YKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLL--NHFGRDFATGAVGQYTVQCPQDL 61
Y+V VATG +GT ++ ++I G +G++ + L + +F G + ++ L
Sbjct: 43 YEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEAVH-L 101
Query: 62 GELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRI-YHFPAYQWMD 106
G+L I + + P + W+ + V I P Y F ++W+D
Sbjct: 102 GDLCKIVIGHD--GLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLD 145
>gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo
sapiens]
Length = 1029
Score = 29.6 bits (65), Expect = 9.9
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 6/106 (5%)
Query: 4 YKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLL--NHFGRDFATGAVGQYTVQCPQDL 61
Y+V VATG +GT ++ ++I G +G++ + L + +F G + ++ L
Sbjct: 43 YEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEAVH-L 101
Query: 62 GELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRI-YHFPAYQWMD 106
G+L I + + P + W+ + V I P Y F ++W+D
Sbjct: 102 GDLCKIVIGHD--GLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLD 145
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.140 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,871,799
Number of Sequences: 37866
Number of extensions: 1370612
Number of successful extensions: 2526
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2471
Number of HSP's gapped (non-prelim): 40
length of query: 701
length of database: 18,247,518
effective HSP length: 109
effective length of query: 592
effective length of database: 14,120,124
effective search space: 8359113408
effective search space used: 8359113408
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.