Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 42794779

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42794779 myosin 18A isoform b [Homo sapiens]
         (2039 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42794779 myosin 18A isoform b [Homo sapiens]                      3969   0.0  
gi|28416946 myosin 18A isoform a [Homo sapiens]                      3959   0.0  
gi|51317366 myosin XVIIIB [Homo sapiens]                             1385   0.0  
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...   599   e-171
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...   598   e-170
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...   597   e-170
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...   597   e-170
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]    588   e-167
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]   581   e-165
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]          531   e-150
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]          528   e-149
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]          527   e-149
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...   515   e-145
gi|156104908 myosin heavy chain 6 [Homo sapiens]                      513   e-145
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...   511   e-144
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...   507   e-143
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...   506   e-143
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...   506   e-143
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...   506   e-142
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...   502   e-141
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...   502   e-141
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...   501   e-141
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]              494   e-139
gi|153945715 myosin VC [Homo sapiens]                                 302   3e-81
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       295   2e-79
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       294   5e-79
gi|122937345 myosin VB [Homo sapiens]                                 286   1e-76
gi|154354979 myosin X [Homo sapiens]                                  228   4e-59
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     225   3e-58
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     225   3e-58

>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 3969 bits (10294), Expect = 0.0
 Identities = 2039/2039 (100%), Positives = 2039/2039 (100%)

Query: 1    MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRL 60
            MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRL
Sbjct: 1    MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRL 60

Query: 61   EISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKGEEGSFRGSVLQR 120
            EISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKGEEGSFRGSVLQR
Sbjct: 61   EISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKGEEGSFRGSVLQR 120

Query: 121  AAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP 180
            AAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP
Sbjct: 121  AAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP 180

Query: 181  GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTM 240
            GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTM
Sbjct: 181  GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTM 240

Query: 241  LDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSG 300
            LDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSG
Sbjct: 241  LDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSG 300

Query: 301  DSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF 360
            DSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF
Sbjct: 301  DSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF 360

Query: 361  SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESS 420
            SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESS
Sbjct: 361  SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESS 420

Query: 421  VLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQT 480
            VLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQT
Sbjct: 421  VLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQT 480

Query: 481  AYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE 540
            AYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE
Sbjct: 481  AYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE 540

Query: 541  AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYY 600
            AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYY
Sbjct: 541  AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYY 600

Query: 601  LLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQK 660
            LLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQK
Sbjct: 601  LLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQK 660

Query: 661  ACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG 720
            ACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG
Sbjct: 661  ACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG 720

Query: 721  GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQH 780
            GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQH
Sbjct: 721  GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQH 780

Query: 781  SLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENI 840
            SLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENI
Sbjct: 781  SLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENI 840

Query: 841  ELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER 900
            ELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER
Sbjct: 841  ELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER 900

Query: 901  LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR 960
            LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR
Sbjct: 901  LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR 960

Query: 961  LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1020
            LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS
Sbjct: 961  LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1020

Query: 1021 LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC 1080
            LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC
Sbjct: 1021 LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC 1080

Query: 1081 EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY 1140
            EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY
Sbjct: 1081 EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY 1140

Query: 1141 IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR 1200
            IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR
Sbjct: 1141 IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR 1200

Query: 1201 GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD 1260
            GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD
Sbjct: 1201 GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD 1260

Query: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320
            EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL
Sbjct: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320

Query: 1321 RAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVR 1380
            RAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVR
Sbjct: 1321 RAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVR 1380

Query: 1381 EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1440
            EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ
Sbjct: 1381 EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1440

Query: 1441 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1500
            DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ
Sbjct: 1441 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1500

Query: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE 1560
            QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE
Sbjct: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE 1560

Query: 1561 QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE 1620
            QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE
Sbjct: 1561 QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE 1620

Query: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680
            DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP
Sbjct: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680

Query: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
            SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE
Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740

Query: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
            KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL
Sbjct: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800

Query: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
            QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD
Sbjct: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860

Query: 1861 QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA 1920
            QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA
Sbjct: 1861 QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA 1920

Query: 1921 DLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSK 1980
            DLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSK
Sbjct: 1921 DLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSK 1980

Query: 1981 AASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYLSDSDTEAKLTETNA 2039
            AASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYLSDSDTEAKLTETNA
Sbjct: 1981 AASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYLSDSDTEAKLTETNA 2039


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 3959 bits (10268), Expect = 0.0
 Identities = 2039/2054 (99%), Positives = 2039/2054 (99%), Gaps = 15/2054 (0%)

Query: 1    MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRL 60
            MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRL
Sbjct: 1    MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRL 60

Query: 61   EISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKGEEGSFRGSVLQR 120
            EISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKGEEGSFRGSVLQR
Sbjct: 61   EISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKGEEGSFRGSVLQR 120

Query: 121  AAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP 180
            AAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP
Sbjct: 121  AAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP 180

Query: 181  GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTM 240
            GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTM
Sbjct: 181  GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTM 240

Query: 241  LDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSG 300
            LDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSG
Sbjct: 241  LDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSG 300

Query: 301  DSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF 360
            DSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF
Sbjct: 301  DSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF 360

Query: 361  SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESS 420
            SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESS
Sbjct: 361  SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESS 420

Query: 421  VLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQT 480
            VLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQT
Sbjct: 421  VLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQT 480

Query: 481  AYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE 540
            AYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE
Sbjct: 481  AYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE 540

Query: 541  AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYY 600
            AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYY
Sbjct: 541  AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYY 600

Query: 601  LLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQK 660
            LLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQK
Sbjct: 601  LLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQK 660

Query: 661  ACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG 720
            ACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG
Sbjct: 661  ACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG 720

Query: 721  GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQH 780
            GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQH
Sbjct: 721  GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQH 780

Query: 781  SLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENI 840
            SLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENI
Sbjct: 781  SLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENI 840

Query: 841  ELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER 900
            ELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER
Sbjct: 841  ELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER 900

Query: 901  LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR 960
            LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR
Sbjct: 901  LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR 960

Query: 961  LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1020
            LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS
Sbjct: 961  LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1020

Query: 1021 LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC 1080
            LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC
Sbjct: 1021 LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC 1080

Query: 1081 EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY 1140
            EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY
Sbjct: 1081 EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY 1140

Query: 1141 IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR 1200
            IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR
Sbjct: 1141 IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR 1200

Query: 1201 GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD 1260
            GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD
Sbjct: 1201 GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD 1260

Query: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320
            EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL
Sbjct: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320

Query: 1321 RAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVR 1380
            RAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVR
Sbjct: 1321 RAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVR 1380

Query: 1381 EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1440
            EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ
Sbjct: 1381 EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1440

Query: 1441 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1500
            DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ
Sbjct: 1441 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1500

Query: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE 1560
            QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE
Sbjct: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE 1560

Query: 1561 QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE 1620
            QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE
Sbjct: 1561 QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE 1620

Query: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680
            DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP
Sbjct: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680

Query: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
            SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE
Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740

Query: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
            KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL
Sbjct: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800

Query: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
            QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD
Sbjct: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860

Query: 1861 QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA 1920
            QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA
Sbjct: 1861 QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA 1920

Query: 1921 DLKLAFKRIGDLQAAIEDEMESDENEDLINS---------------EGDSDVDSELEDRV 1965
            DLKLAFKRIGDLQAAIEDEMESDENEDLINS               EGDSDVDSELEDRV
Sbjct: 1921 DLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRV 1980

Query: 1966 DGVKSWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYL 2025
            DGVKSWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYL
Sbjct: 1981 DGVKSWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYL 2040

Query: 2026 SDSDTEAKLTETNA 2039
            SDSDTEAKLTETNA
Sbjct: 2041 SDSDTEAKLTETNA 2054


>gi|51317366 myosin XVIIIB [Homo sapiens]
          Length = 2567

 Score = 1385 bits (3584), Expect = 0.0
 Identities = 756/1671 (45%), Positives = 1131/1671 (67%), Gaps = 44/1671 (2%)

Query: 322  RSGEGPRREPSDAKTEEQIAA-EEAWNETEKVWLVHRDGFSLASQLKSEE--LNLPEGKV 378
            + G  P+ E    ++ +   A E+ W E EKVWL  +DGF+LA+ LK +E   +LP G+V
Sbjct: 485  QDGPAPQEEGKGGQSRDSDQAPEDRWYEAEKVWLAQKDGFTLATVLKPDEGTADLPAGRV 544

Query: 379  RVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYA 438
            R+ +D D  I +VDE+ V +AN P  D++EDLASL+ +NESSVL+TL QRY A LLHT  
Sbjct: 545  RLWIDADKTITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCT 604

Query: 439  GPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLG 498
            GP L+VL PRG     + KV    KG RR+ +  HI ++AQ AY A+L  R+DQSI+ LG
Sbjct: 605  GPDLIVLQPRGPSVPSAGKVP---KG-RRDGLPAHIGSMAQRAYWALLNQRRDQSIVALG 660

Query: 499  SSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLEAFGNSPTIINGNATRFSQ 558
             SG+GKTT C+ ++++L  +AG    +V SVEK +A +T+L AFG+     + +ATRFS 
Sbjct: 661  WSGAGKTTCCEQVLEHLVGMAGSVDGRV-SVEKIRATFTVLRAFGSVSMAHSRSATRFSM 719

Query: 559  ILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHL 618
            ++SLDF+  G++ +A +QTMLLEK RVAR+P  E+ F VF  +LA  D  LRTEL+L+ +
Sbjct: 720  VMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQM 779

Query: 619  AENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGAT 678
            A+++ FG+   +KPE+KQKAA  F++LQ AM++LGIS  EQ+A W +LAAIYHLGAAGA 
Sbjct: 780  ADSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGAC 839

Query: 679  KEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGL 738
            K     GRKQF R EWA  AA  LGC  EEL++A FKH H    +Q+ T    GP   GL
Sbjct: 840  K----VGRKQFMRFEWANYAAEALGCEYEELNTATFKH-HLRQIIQQMTF---GPSRWGL 891

Query: 739  GD---GTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQN 795
             D    +G K++ ++C+EGMA+GLY ELF  +VSL+NR+  S   S+ S+M+VD+PGFQN
Sbjct: 892  EDEETSSGLKMTGVDCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQN 951

Query: 796  PEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSV 855
            P   G  R A+FEELCHNY  +RLQ LF++RTFV  L+RY+EE + + FD  +P    +V
Sbjct: 952  PRHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTV 1011

Query: 856  AAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQ 915
            A VDQ   Q  + +     +ARGL W+L+EE  V G+S+  +LERL + +  +    +G 
Sbjct: 1012 AVVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGS 1071

Query: 916  SPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFL 975
            S L    +P    + H  G + V Y++TGWL+  K N +  +AP++L  S+++ + +LF 
Sbjct: 1072 SALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQ 1131

Query: 976  GRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDT 1035
             RA    V   ++AGLEG SQ AL+R+  +R+TF + +AAV++K+ C Q+KLQ+DAL   
Sbjct: 1132 ARAKLPPVCR-AVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSM 1190

Query: 1036 IKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQ 1095
            IK+S+LHF+HC +P       E RS            D P       G L LD+P LR Q
Sbjct: 1191 IKRSRLHFIHCLVPNP---VVESRSGQESPPPPQPGRDKPGA----GGPLALDIPALRVQ 1243

Query: 1096 LRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLEC 1155
            L G  +L+A+R++R GY DHM  + FRR+F VL   L KK       +DER+AVEELLE 
Sbjct: 1244 LAGFHILEALRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLET 1303

Query: 1156 LDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQD 1215
            LDLEK +  +G S+VF +AG ++RLE+QR++  S+++ LFQAAC+G+L+RQ FKK KI+ 
Sbjct: 1304 LDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRR 1363

Query: 1216 LAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEK 1275
            LA +C+QKN+     VKDWPWW+L  +++PL+   +  EQ+R K+EE+  LR KLEK+EK
Sbjct: 1364 LAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEK 1423

Query: 1276 ERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDA 1335
             RNELR N+D LES+I++LTS+L DER  G+ A Q+L++E AERL+A +E++EL+++++ 
Sbjct: 1424 LRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQ 1483

Query: 1336 LKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGG--EWRLKYERAVREVDFTKKRLQQEF 1393
            ++K++  +  ++ EA+  +  ++N +++ +  GG  EW+++++ A  E +F +KRLQQ  
Sbjct: 1484 VQKKLGDVNKQLEEAQ--QKIQLN-DLERNPTGGADEWQMRFDCAQMENEFLRKRLQQ-C 1539

Query: 1394 EDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRN 1453
            E++L+ E   +++LE++LG+LQ+  + +++   QLK+KC  LT +L+DT + LE QQ RN
Sbjct: 1540 EERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRN 1599

Query: 1454 HELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFT 1513
            HELEKKQ++FD +L+QA  E+  EK  REK+ +E   +  E   L+QQL++K+ + +   
Sbjct: 1600 HELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLK 1659

Query: 1514 QKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKL 1573
            Q+V  L+   +++    S  E  +A +K++L  LE+   +Q++   +Q  TI+ LEQ + 
Sbjct: 1660 QQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQ 1719

Query: 1574 RLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633
            R E+E+ERM+Q H K+ E ++EE+E+ RQSCQK+L Q+E+QLE+EYE+KQ VL EK++LE
Sbjct: 1720 RFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLE 1779

Query: 1634 GKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKN--SAPSKREIAQLKNQ 1691
            G + TL DQ+  RDF+ EKRLR+DL+RT ALL+D QL+L  +++  ++ SK E+ ++ +Q
Sbjct: 1780 GLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQ 1839

Query: 1692 LEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEED 1751
            LE+SE  C  A+K +K +  ++E +H +++++ + K+ ++EQL RLQ EK ++  R++ED
Sbjct: 1840 LEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDED 1899

Query: 1752 QEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM 1811
            Q+D+NELM+KHK  +AQ++ D+ QI +LQ QLEEA KEK +LQE+LQ  Q ++E+LEQS 
Sbjct: 1900 QDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQST 1959

Query: 1812 VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871
            VD+++VSRQEA I +LE + EF++ Q+KR E L  RL++++ K+ EE  Q   +E++++E
Sbjct: 1960 VDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRE 2019

Query: 1872 QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGD 1931
             ++  QR+L + K +M EL ++EAEASR+  ELE  +E L A  Q+LQ DL+ + +RI D
Sbjct: 2020 SSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIAD 2079

Query: 1932 LQAAIEDEMESDENEDLI------NSEGDSDVD--SELEDRVDG-VKSWLS 1973
            LQAA+E+   SD + + +       S G  ++D  S L  + +G ++SWLS
Sbjct: 2080 LQAALEEVASSDSDTESVQTAVDCGSSGRKEMDNVSILSSQPEGSLQSWLS 2130


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score =  599 bits (1545), Expect = e-171
 Identities = 497/1750 (28%), Positives = 865/1750 (49%), Gaps = 272/1750 (15%)

Query: 342  AEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400
            A+  W     VW+   + GF  AS +K E+ +    +V V+L  +G  + V +DD++K N
Sbjct: 26   AQADWAAKRLVWVPSEKQGFEAAS-IKEEKGD----EVVVELVENGKKVTVGKDDIQKMN 80

Query: 401  APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460
             P   ++ED+A L  LNE+SVLH LR+RY + L++TY+G   +V+ P     +YSEK++ 
Sbjct: 81   PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140

Query: 461  MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520
            M+KG +R +M PHIYA+A TAYR+ML  R+DQSI+  G SG+GKT + + ++QYLA +A 
Sbjct: 141  MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200

Query: 521  I-SGNKVFSVE---KWQALYT--LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASAS 574
               G K  S+    + Q L    +LEAFGN+ T+ N N++RF + + ++FD  G +  A+
Sbjct: 201  SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260

Query: 575  IQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHL----NHLAENNVFGIVPLA 630
            I+T LLEK R  R+   E TF++FYY++A     +R++L L    N+   +N F  +P A
Sbjct: 261  IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 320

Query: 631  KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
            + +E       F +   AM ++G S +EQ +   +++++  LG     KE     +    
Sbjct: 321  QDDE------MFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKER-NTDQASMP 373

Query: 691  RHEWAQKAAYLLGCSLEELSSAIFKHQHKGG--TLQRSTSFRQGPEESGLGDGTGPKLSA 748
             +  AQK  +L+G ++ + + +I   + K G   +Q++ +  Q                A
Sbjct: 374  DNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQ----------------A 417

Query: 749  LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
               +E +A   Y  LF  +++ VN+AL  +     S + I+D  GF+  E        SF
Sbjct: 418  DFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVN------SF 471

Query: 808  EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
            E+LC NYT ++LQ+LF+   F+ E E Y+ E IE  F D                 Q  +
Sbjct: 472  EQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFG------------LDLQPCI 519

Query: 868  RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
              + R +   G+L LL+EE   P A++ + +E+L +  G      K Q P     K    
Sbjct: 520  ELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHP---KFQKPKQLKDKTEFS 576

Query: 928  LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGS 987
            ++   H    V+YN + WL     +P   N   LL  S  K +++L+             
Sbjct: 577  II---HYAGKVDYNASAWLT-KNMDPLNDNVTSLLNASSDKFVADLWKD--------VDR 624

Query: 988  IAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCF 1047
            I GL+  +++      S  KT   GM     +++    K Q+  L+ T++ +  +FV C 
Sbjct: 625  IVGLDQMAKMTESSLPSASKT-KKGMF----RTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679

Query: 1048 LPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRM 1107
            +P  E  +G+                             LD  L+  QLR + +L+ +R+
Sbjct: 680  IPNHEKRSGK-----------------------------LDAFLVLEQLRCNGVLEGIRI 710

Query: 1108 YRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGL 1167
             RQG+P+ +VF EFR+R+++LA +   K       +D ++A   +++ L+L+ +   +G 
Sbjct: 711  CRQGFPNRIVFQEFRQRYEILAANAIPKG-----FMDGKQACILMIKALELDPNLYRIGQ 765

Query: 1168 SRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKK 1227
            S++FFR G LA LEE+RD + +  +  FQA CRGYLAR+ F KR+ Q  A++ +Q+N   
Sbjct: 766  SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825

Query: 1228 NKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRL 1287
               +++W WW+LFT V+PL++V   EE+++ K++E+Q+ + + +KAE E  EL       
Sbjct: 826  YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKEL------- 878

Query: 1288 ESRISELTSE--LTDERNTGESASQLLDAETAERLRAEK-EMKELQTQYDALKKQMEVME 1344
            E + S+LT E  L  E+   E+       E   RL A+K E++E+  + +A  ++ E   
Sbjct: 879  EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938

Query: 1345 MEVMEARLIRAAE---INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEF---EDKLE 1398
             ++   R   A +   +  ++++++A  + +L+ E+   E     K+L+ E    +D+  
Sbjct: 939  QQLQAERKKMAQQMLDLEEQLEEEEAARQ-KLQLEKVTAEAKI--KKLEDEILVMDDQNN 995

Query: 1399 VEQQNKRQLERRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455
               + ++ LE R+ DL    A+ EE  + L +LK K + + +EL+   + L+ ++    E
Sbjct: 996  KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKKEEKSRQE 1052

Query: 1456 LEKKQRRFDSELSQAHEE-----AQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIA 1510
            LEK +R+ + + S  HE+     AQ  +L+ +  ++E+++  A A  L  ++ +K+  + 
Sbjct: 1053 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA-RLDDEIAQKNNAL- 1110

Query: 1511 GFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDL----EAKVKDQEEELD------- 1559
               +K+  LE  + D+      + A+  K +KQ RDL    EA   + E+ LD       
Sbjct: 1111 ---KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167

Query: 1560 -----EQAGTI--QMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME 1612
                 EQ  T+  + L++     E +++ MRQ H++ +E   E++E+ +++ +  L + +
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA-KANLDKNK 1226

Query: 1613 VQLEEEYED-----------KQKVLREKRELEGKL--------------ATLSDQVNRRD 1647
              LE+E  D           KQ+V  +K++LE ++              A L+D+V++  
Sbjct: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286

Query: 1648 FESEK-------------RLRKDLKRTKALLADAQLML---------------------- 1672
             E E              +L KD+    + L D Q +L                      
Sbjct: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346

Query: 1673 ---DHLKNSAPSKR-----------EIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHL 1718
               D L     +K+           +++  K +L++   T  A  + +K  + EIE+L  
Sbjct: 1347 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406

Query: 1719 QIDDIAKAKTALEEQLSRLQRE----------KNEIQNRLEEDQEDMNELMKKHK----- 1763
            Q ++ A A   LE+  +RLQ+E          + ++ + LE+ Q   ++L+ + K     
Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466

Query: 1764 ------AAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSL- 1816
                   A A+A     +   L   LEEA + K+EL+   + L++++E L  S  D    
Sbjct: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526

Query: 1817 VSRQEAKIRELETRLEFERTQVKRLESLAS-------RLKENMEKLTEERDQRIAAENRE 1869
            V   E   R LET++E  +TQ++ LE           RL+ NM+ L  + ++ + A + +
Sbjct: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1586

Query: 1870 KEQNKR-LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKR 1928
             E+ +R LQRQL + + E+ +  ++ A A+  K +LE DL+ LE    S     + A K+
Sbjct: 1587 NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1646

Query: 1929 IGDLQAAIED 1938
            +  LQA ++D
Sbjct: 1647 LRKLQAQMKD 1656



 Score =  231 bits (589), Expect = 5e-60
 Identities = 189/738 (25%), Positives = 372/738 (50%), Gaps = 61/738 (8%)

Query: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNELRL 1282
            N+ KNK   +     L   +R L + +   E  + K E ++Q+L+SK    E+ R EL  
Sbjct: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1280

Query: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328
               +L++ +  +T  L +                   +   +LL  ET ++L    ++++
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340

Query: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKR 1388
            L+ + ++L+ Q++  EME  +      + +N ++ D                    +KK+
Sbjct: 1341 LEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSD--------------------SKKK 1379

Query: 1389 LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
            LQ +F   +E  ++ K++ ++ + +L    EE   A  +L+K   RL  EL D  + L+ 
Sbjct: 1380 LQ-DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438

Query: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
            Q+     LEKKQR+FD  L++    + +   +R++ + E      +A SL + LEE    
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498

Query: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
                 +    L+AE++D+ S +     ++ +++K  R LE ++++ + +L+E    +Q  
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558

Query: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
            E AKLRLE+ M+ ++    +++++RDE+ EE R+  Q++L + E +LE+E + +      
Sbjct: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618

Query: 1629 KRELEGKLATL---SDQVNRRDFESEKRLRK---DLKRTKALLADAQLMLDHLKNSA-PS 1681
            K++LEG L  L   +D   +   E+ K+LRK    +K  +  L DA+   D +  +A  +
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678

Query: 1682 KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
            +++   L+  L + +   AAA +ARK  ++E E+L  ++      + AL+++  RL+   
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738

Query: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
             +++  LEE+Q +M  +  + + A  QA +   ++   ++  ++    +Q+L+ + + L+
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798

Query: 1802 SQVEFLEQSMVD--KSLVSRQEAKIRELETRLEFE-RTQVKRLESLASRLKENMEKLTEE 1858
            S++  +E ++    KS ++  EAKI +LE ++E E R +    +SL  + K+  E L + 
Sbjct: 1799 SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV 1858

Query: 1859 RDQRIAAENREKEQN------KRLQRQLRDTKEEMGELARKEAEASRKKHELEMD--LES 1910
             D+R  AE  +++        K+L+RQL + +EE      +   A+R+K + E+D   ES
Sbjct: 1859 EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE-----SQRINANRRKLQRELDEATES 1913

Query: 1911 LEAANQSLQADLKLAFKR 1928
             EA  + + A LK   +R
Sbjct: 1914 NEAMGREVNA-LKSKLRR 1930



 Score =  173 bits (438), Expect = 2e-42
 Identities = 185/813 (22%), Positives = 352/813 (43%), Gaps = 137/813 (16%)

Query: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL-- 1311
            EQI +   +I +L+ +L K E+E   L+    RL+  I++  + L   R      S L  
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEE---LQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125

Query: 1312 -LDAETAERLRAEKEMKELQTQYDALKKQME------VMEMEVMEARLIRAAEINGEVDD 1364
             LD+E A R +AEK+ ++L  + +ALK ++E        + E+   R      +   +D+
Sbjct: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185

Query: 1365 DDAGGE-----WRLKYERAVRE--------------VDFTKKRLQQEFED---------- 1395
            +    E      R K+ +AV E              +D  K+ L++E  D          
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1245

Query: 1396 -KLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRL------------------- 1435
             K EVE + K++LE ++ +LQ+   + +RA  +L  K  +L                   
Sbjct: 1246 AKQEVEHK-KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI 1304

Query: 1436 ---------TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQR 1486
                     +++LQDT+  L+ +  +   +  K R+ + E +   ++   E   ++ L+R
Sbjct: 1305 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1364

Query: 1487 EKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1546
                L  +    K++L++    +    +     + E+++++ Q  +  A+  K++K    
Sbjct: 1365 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424

Query: 1547 LEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQK 1606
            L+ ++ D   +LD Q   +  LE+ + + +  +   +   SK  + RD    EAR+   K
Sbjct: 1425 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1484

Query: 1607 KLKQMEVQLEEEYEDKQKVLREKRELEGKLATL---SDQVNRRDFESEKRLR-------- 1655
             L      LEE  E K+++ R  + L+ ++  L    D V +   E EK  R        
Sbjct: 1485 ALSLARA-LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1543

Query: 1656 -----KDLKRTKALLADAQLMLD--------------------HLKNSAPSKREIAQLKN 1690
                 ++L+       DA+L L+                    + +     +R++ + + 
Sbjct: 1544 MKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET 1603

Query: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750
            +LE+     A A  A+K +E +++DL LQ D   K +    +QL +LQ +  + Q  LE+
Sbjct: 1604 ELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663

Query: 1751 DQEDMNELM---KKHKAAVAQASRDLAQINDLQAQLEEANK----EKQELQEKLQALQSQ 1803
             +   +E+    K+++        DL Q+ +  A  E A K    EK+EL E+L +  S 
Sbjct: 1664 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1723

Query: 1804 VEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQR 1862
               L+          R EA+I +LE  LE E+  ++ +     +  +  E+L+ E   +R
Sbjct: 1724 RNALQDEK------RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1777

Query: 1863 IAAENRE--KEQNKRLQRQLRDTKEEM---------GELARKEAEASRKKHELEMDLESL 1911
              A+  E  ++Q +R  ++LR    EM           +A  EA+ ++ + ++E +    
Sbjct: 1778 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREK 1837

Query: 1912 EAANQSLQADLKLAFKRIGDLQAAIEDEMESDE 1944
            +AA +SL    K   K++ ++   +EDE +  E
Sbjct: 1838 QAATKSL----KQKDKKLKEILLQVEDERKMAE 1866


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score =  598 bits (1543), Expect = e-170
 Identities = 462/1684 (27%), Positives = 838/1684 (49%), Gaps = 187/1684 (11%)

Query: 342  AEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400
            A+  W     VW+   + GF  AS +K E+ +    +V V+L  +G  + V +DD++K N
Sbjct: 26   AQADWAAKRLVWVPSEKQGFEAAS-IKEEKGD----EVVVELVENGKKVTVGKDDIQKMN 80

Query: 401  APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460
             P   ++ED+A L  LNE+SVLH LR+RY + L++TY+G   +V+ P     +YSEK++ 
Sbjct: 81   PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140

Query: 461  MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520
            M+KG +R +M PHIYA+A TAYR+ML  R+DQSI+  G SG+GKT + + ++QYLA +A 
Sbjct: 141  MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200

Query: 521  I-SGNKVFSV-----EKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASAS 574
               G K  S+     ++      +LEAFGN+ T+ N N++RF + + ++FD  G +  A+
Sbjct: 201  SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260

Query: 575  IQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHL----NHLAENNVFGIVPLA 630
            I+T LLEK R  R+   E TF++FYY++A     +R++L L    N+   +N F  +P A
Sbjct: 261  IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 320

Query: 631  KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
            + +E       F +   AM ++G S +EQ +   +++++  LG     KE     +    
Sbjct: 321  QDDE------MFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKE-RNTDQASMP 373

Query: 691  RHEWAQKAAYLLGCSLEELSSAIFKHQHKGG--TLQRSTSFRQGPEESGLGDGTGPKLSA 748
             +  AQK  +L+G ++ + + +I   + K G   +Q++ +                K  A
Sbjct: 374  DNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT----------------KEQA 417

Query: 749  LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
               +E +A   Y  LF  +++ VN+AL  +     S + I+D  GF+  E        SF
Sbjct: 418  DFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVN------SF 471

Query: 808  EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
            E+LC NYT ++LQ+LF+   F+ E E Y+ E IE  F D                 Q  +
Sbjct: 472  EQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF------------GLDLQPCI 519

Query: 868  RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
              + R +   G+L LL+EE   P A++ + +E+L +  G      K Q P     K    
Sbjct: 520  ELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG---SHPKFQKPKQLKDKTEFS 576

Query: 928  LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGS 987
            ++   H    V+YN + WL     +P   N   LL  S  K +++L+             
Sbjct: 577  II---HYAGKVDYNASAWLT-KNMDPLNDNVTSLLNASSDKFVADLWKD--------VDR 624

Query: 988  IAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCF 1047
            I GL+  +++      S  KT   GM     +++    K Q+  L+ T++ +  +FV C 
Sbjct: 625  IVGLDQMAKMTESSLPSASKT-KKGMF----RTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679

Query: 1048 LPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRM 1107
            +P  E  +G                             +LD  L+  QLR + +L+ +R+
Sbjct: 680  IPNHEKRSG-----------------------------KLDAFLVLEQLRCNGVLEGIRI 710

Query: 1108 YRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGL 1167
             RQG+P+ +VF EFR+R+++LA +   K       +D ++A   +++ L+L+ +   +G 
Sbjct: 711  CRQGFPNRIVFQEFRQRYEILAANAIPKG-----FMDGKQACILMIKALELDPNLYRIGQ 765

Query: 1168 SRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKK 1227
            S++FFR G LA LEE+RD + +  +  FQA CRGYLAR+ F KR+ Q  A++ +Q+N   
Sbjct: 766  SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825

Query: 1228 NKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRL 1287
               +++W WW+LFT V+PL++V   EE+++ K++E+Q+ + + +KAE E  E       L
Sbjct: 826  YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKE-------L 878

Query: 1288 ESRISELTSE--LTDERNTGESASQLLDAETAERLRAEK-EMKELQTQYDALKKQMEVME 1344
            E + S+LT E  L  E+   E+       E   RL A+K E++E+  + +A  ++ E   
Sbjct: 879  EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938

Query: 1345 MEVMEARLIRA---AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQE---FEDKLE 1398
             ++   R   A    ++  ++++++A  + +L+ E+   E     K+L+ E    +D+  
Sbjct: 939  QQLQAERKKMAQQMLDLEEQLEEEEAARQ-KLQLEKVTAEAKI--KKLEDEILVMDDQNN 995

Query: 1399 VEQQNKRQLERRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455
               + ++ LE R+ DL    A+ EE  + L +LK K + + +EL+   + L+ ++    E
Sbjct: 996  KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKKEEKSRQE 1052

Query: 1456 LEKKQRRFDSELSQAHE-----EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIA 1510
            LEK +R+ + + S  HE     +AQ  +L+ +  ++E+++  A A  L  ++ +K+  + 
Sbjct: 1053 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA-RLDDEIAQKNNAL- 1110

Query: 1511 GFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQ 1570
               +K+  LE  + D+      + A+  K +KQ RDL  +++  + EL++   +    ++
Sbjct: 1111 ---KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167

Query: 1571 AKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY-------EDKQ 1623
             + + E E+  +++   +E  S + +V+E RQ   + ++++  QLE+         ++KQ
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227

Query: 1624 KVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS-K 1682
             + +E  +L G+L  L  Q  +     +K+L   ++  ++  +D +     L +     +
Sbjct: 1228 TLEKENADLAGELRVLG-QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286

Query: 1683 REIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1742
             E+  +   L E+E       K   ++  +++D    + +  + K  +  +L +L+ E+N
Sbjct: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346

Query: 1743 EIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS 1802
             +Q++L+E+ E    L +       Q S    ++ D  + +E   + K+  Q++++ L  
Sbjct: 1347 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406

Query: 1803 QVEFLEQSMVDK--SLVSRQEAKIRELETRLEFERTQVKRLE-------SLASRLKENME 1853
            Q E  + +  DK     +R + ++ +L   L+ +R  V  LE        L +  K    
Sbjct: 1407 QYE-EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISS 1465

Query: 1854 KLTEERDQRIAAENREK---------------EQNKRLQRQLRDTKEEMGELARKEAEAS 1898
            K  +ERD R  AE REK               E  + L+R  +  K EM +L   + +  
Sbjct: 1466 KYADERD-RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1524

Query: 1899 RKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD 1958
            +  HELE    +LE   + ++  L+   +   +LQA  + ++  + N   +  + + D+ 
Sbjct: 1525 KNVHELEKSKRALETQMEEMKTQLE---ELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581

Query: 1959 SELE 1962
            +  E
Sbjct: 1582 ARDE 1585



 Score =  231 bits (588), Expect = 7e-60
 Identities = 187/730 (25%), Positives = 367/730 (50%), Gaps = 60/730 (8%)

Query: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNELRL 1282
            N+ KNK   +     L   +R L + +   E  + K E ++Q+L+SK    E+ R EL  
Sbjct: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1280

Query: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328
               +L++ +  +T  L +                   +   +LL  ET ++L    ++++
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340

Query: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKR 1388
            L+ + ++L+ Q++  EME  +      + +N ++ D                    +KK+
Sbjct: 1341 LEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSD--------------------SKKK 1379

Query: 1389 LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
            LQ +F   +E  ++ K++ ++ + +L    EE   A  +L+K   RL  EL D  + L+ 
Sbjct: 1380 LQ-DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438

Query: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
            Q+     LEKKQR+FD  L++    + +   +R++ + E      +A SL + LEE    
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498

Query: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
                 +    L+AE++D+ S +     ++ +++K  R LE ++++ + +L+E    +Q  
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558

Query: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
            E AKLRLE+ M+ ++    +++++RDE+ EE R+  Q++L + E +LE+E + +      
Sbjct: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618

Query: 1629 KRELEGKLATL---SDQVNRRDFESEKRLRK---DLKRTKALLADAQLMLDHLKNSAPSK 1682
            K++LEG L  L   +D   +   E+ K+LRK    +K  +  L DA+   D +  +A   
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678

Query: 1683 REIAQ-LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
             + A+ L+  L + +   AAA +ARK  ++E E+L  ++      + AL+++  RL+   
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738

Query: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
             +++  LEE+Q +M  +  + + A  QA +   ++   ++  ++    +Q+L+ + + L+
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798

Query: 1802 SQVEFLEQSMVDK--SLVSRQEAKIRELETRLEFE-RTQVKRLESLASRLKENMEKLTEE 1858
            S++  +E ++  K  S ++  EAKI +LE ++E E R +    +SL  + K+  E L + 
Sbjct: 1799 SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV 1858

Query: 1859 RDQRIAAENREKEQNK------RLQRQLRDTKEEMGELARKEAEASRKKHELEMD--LES 1910
             D+R  AE  +++  K      +L+RQL + +EE      +   A+R+K + E+D   ES
Sbjct: 1859 EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE-----SQRINANRRKLQRELDEATES 1913

Query: 1911 LEAANQSLQA 1920
             EA  + + A
Sbjct: 1914 NEAMGREVNA 1923



 Score =  179 bits (455), Expect = 2e-44
 Identities = 197/856 (23%), Positives = 373/856 (43%), Gaps = 62/856 (7%)

Query: 1180 LEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKL 1239
            LEEQ +E+ +    L         A    KK + + L +      + K + + +     L
Sbjct: 955  LEEQLEEEEAARQKL---QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1011

Query: 1240 FTTVRPLIEVQLSEEQIRNKDEE-IQQLRSKLEKAEKERNEL-----RLNSDR------- 1286
             T +    E   +  +++NK E  I +L  +L+K EK R EL     +L  D        
Sbjct: 1012 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI 1071

Query: 1287 --LESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQM---- 1340
              L+++I+EL  +L  +    ++A   LD E A++  A K+++EL+     L++ +    
Sbjct: 1072 ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1131

Query: 1341 ------EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE 1394
                  E  + ++ E       E+   +D      E R K E+   EV   KK L +E  
Sbjct: 1132 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ---EVTVLKKALDEETR 1188

Query: 1395 DKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNH 1454
                  Q+ +++  + + +L    E+ +RA   L K  Q L  E  D    L        
Sbjct: 1189 SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248

Query: 1455 ELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQ 1514
            E+E K+++ ++++ +   +    +  R +L  +   L  E  S+   L E +       +
Sbjct: 1249 EVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308

Query: 1515 KVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLR 1574
             V SL ++LQD      ++      V  +LR LE +    +++LDE+    Q LE+    
Sbjct: 1309 DVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIST 1368

Query: 1575 LEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEG 1634
            L +++   ++   ++  S  E +EE ++  QK+++ +  Q EE+     K+ + K  L+ 
Sbjct: 1369 LNIQLSDSKKK-LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ 1427

Query: 1635 KLATLS-DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLE 1693
            +L  L  D  N+R   S   L K  ++   LLA+ +    ++ +    +R+ A+ + + +
Sbjct: 1428 ELDDLVVDLDNQRQLVSN--LEKKQRKFDQLLAEEK----NISSKYADERDRAEAEAREK 1481

Query: 1694 ESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE 1753
            E++     A+   +A+E  +E           AK  LE     L+ E  ++ +  ++  +
Sbjct: 1482 ETK-----ALSLARALEEALE-----------AKEELERTNKMLKAEMEDLVSSKDDVGK 1525

Query: 1754 DMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD 1813
            +++EL K  +A   Q      Q+ +L+ +L+     K  L+  +QAL+ Q E   Q+  +
Sbjct: 1526 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1585

Query: 1814 KSLVSRQEAK--IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871
            ++   R++ +  + E ET LE ER Q     +   +L+ +++ L  + D  I       +
Sbjct: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645

Query: 1872 QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLA--FKRI 1929
            Q ++LQ Q++D + E+ +      E      E E   +SLEA    LQ DL  A   ++ 
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1705

Query: 1930 GDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLK 1989
             DL+   ++E+  +    L       D    LE R+  ++  L + +G  +A SD     
Sbjct: 1706 ADLE---KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762

Query: 1990 SSSPTSYWKSLAPDRS 2005
            +         LA +RS
Sbjct: 1763 TQQAEQLSNELATERS 1778



 Score =  173 bits (438), Expect = 2e-42
 Identities = 185/813 (22%), Positives = 352/813 (43%), Gaps = 137/813 (16%)

Query: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL-- 1311
            EQI +   +I +L+ +L K E+E   L+    RL+  I++  + L   R      S L  
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEE---LQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125

Query: 1312 -LDAETAERLRAEKEMKELQTQYDALKKQME------VMEMEVMEARLIRAAEINGEVDD 1364
             LD+E A R +AEK+ ++L  + +ALK ++E        + E+   R      +   +D+
Sbjct: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185

Query: 1365 DDAGGE-----WRLKYERAVRE--------------VDFTKKRLQQEFED---------- 1395
            +    E      R K+ +AV E              +D  K+ L++E  D          
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1245

Query: 1396 -KLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRL------------------- 1435
             K EVE + K++LE ++ +LQ+   + +RA  +L  K  +L                   
Sbjct: 1246 AKQEVEHK-KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI 1304

Query: 1436 ---------TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQR 1486
                     +++LQDT+  L+ +  +   +  K R+ + E +   ++   E   ++ L+R
Sbjct: 1305 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1364

Query: 1487 EKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1546
                L  +    K++L++    +    +     + E+++++ Q  +  A+  K++K    
Sbjct: 1365 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424

Query: 1547 LEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQK 1606
            L+ ++ D   +LD Q   +  LE+ + + +  +   +   SK  + RD    EAR+   K
Sbjct: 1425 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1484

Query: 1607 KLKQMEVQLEEEYEDKQKVLREKRELEGKLATL---SDQVNRRDFESEKRLR-------- 1655
             L      LEE  E K+++ R  + L+ ++  L    D V +   E EK  R        
Sbjct: 1485 ALSLARA-LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1543

Query: 1656 -----KDLKRTKALLADAQLMLD--------------------HLKNSAPSKREIAQLKN 1690
                 ++L+       DA+L L+                    + +     +R++ + + 
Sbjct: 1544 MKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET 1603

Query: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750
            +LE+     A A  A+K +E +++DL LQ D   K +    +QL +LQ +  + Q  LE+
Sbjct: 1604 ELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663

Query: 1751 DQEDMNELM---KKHKAAVAQASRDLAQINDLQAQLEEANK----EKQELQEKLQALQSQ 1803
             +   +E+    K+++        DL Q+ +  A  E A K    EK+EL E+L +  S 
Sbjct: 1664 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1723

Query: 1804 VEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQR 1862
               L+          R EA+I +LE  LE E+  ++ +     +  +  E+L+ E   +R
Sbjct: 1724 RNALQDEK------RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1777

Query: 1863 IAAENRE--KEQNKRLQRQLRDTKEEM---------GELARKEAEASRKKHELEMDLESL 1911
              A+  E  ++Q +R  ++LR    EM           +A  EA+ ++ + ++E +    
Sbjct: 1778 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREK 1837

Query: 1912 EAANQSLQADLKLAFKRIGDLQAAIEDEMESDE 1944
            +AA +SL    K   K++ ++   +EDE +  E
Sbjct: 1838 QAATKSL----KQKDKKLKEILLQVEDERKMAE 1866



 Score =  120 bits (301), Expect = 1e-26
 Identities = 132/583 (22%), Positives = 263/583 (45%), Gaps = 60/583 (10%)

Query: 1174 AGTLARLEE--QRDEQTSRNLTL-FQAACRGYLARQHFKKRKIQDLAIRCV----QKNIK 1226
            A T+  LEE  +R ++   NLT  ++     Y   +  K R  Q+L    V    Q+ + 
Sbjct: 1384 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1443

Query: 1227 KNKGVKDWPWWKLFTTVRPLI-----EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELR 1281
             N   K   + +L    + +      E   +E + R K+ +   L   LE+A + + EL 
Sbjct: 1444 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1503

Query: 1282 LNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQME 1341
              +  L++ + +L S   D    G++  +L           EK  + L+TQ + +K Q+E
Sbjct: 1504 RTNKMLKAEMEDLVSSKDD---VGKNVHEL-----------EKSKRALETQMEEMKTQLE 1549

Query: 1342 VMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ 1401
             +E E+                 +DA    +L+ E  ++ +   K + +++ + + E  +
Sbjct: 1550 ELEDELQAT--------------EDA----KLRLEVNMQAL---KGQFERDLQARDEQNE 1588

Query: 1402 QNKRQLERRLGDLQADSEES--QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKK 1459
            + +RQL+R+L + + + E+   QRAL    KK  +L  +L+D +L  +       E  K+
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDLKDLELQADSAIKGREEAIKQ 1646

Query: 1460 QRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL 1519
             R+  +++     E +  +  R+++         +A SL+  L +   D+A   +     
Sbjct: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1706

Query: 1520 EAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEM 1579
            + E ++++ + +   +    ++ + R LEA++   EEEL+E+ G ++ +     +   + 
Sbjct: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766

Query: 1580 ERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE-EYEDKQKVLREKRELEGKLAT 1638
            E++    + E  S  ++ E ARQ  +++ K++  +L E E   K K       LE K+A 
Sbjct: 1767 EQLSNELATE-RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1825

Query: 1639 LSDQVNRRDFESE---KRLRKDLKRTKALL---ADAQLMLDHLKNSA-PSKREIAQLKNQ 1691
            L +QV +   E +   K L++  K+ K +L    D + M +  K  A      + QLK Q
Sbjct: 1826 LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1885

Query: 1692 LEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734
            LEE+E         R+ ++ E+++     + + +   AL+ +L
Sbjct: 1886 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 96/465 (20%), Positives = 190/465 (40%), Gaps = 106/465 (22%)

Query: 1179 RLEEQRDEQTSRNLTLFQAACRGYLARQHFK------KRKIQDLAIRC--VQKNI---KK 1227
            R E +  E+ ++ L+L +A      A++  +      K +++DL      V KN+   +K
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1532

Query: 1228 NKGVKDWPWWKLFTTVRPLI-EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDR 1286
            +K   +    ++ T +  L  E+Q +E+     +  +Q L+ + E+  + R+E      R
Sbjct: 1533 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1592

Query: 1287 -LESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDA---------- 1335
             L+ ++ E  +EL DER     A+       A + + E ++K+L+ Q D+          
Sbjct: 1593 QLQRQLHEYETELEDERKQRALAA-------AAKKKLEGDLKDLELQADSAIKGREEAIK 1645

Query: 1336 ----LKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGG-----------EWRLKYERAVR 1380
                L+ QM+  + E+ +AR  R  EI     +++              E     ERA +
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRD-EIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1704

Query: 1381 EVDFTKKRLQQEFEDKLEVE---QQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
            + D  K+ L +E    L      Q  KR+LE R+  L+ + EE Q  ++ +  + ++ T 
Sbjct: 1705 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1764

Query: 1438 ELQDT-------------------KLHLEGQQVRN--HELEKKQRR--------FDSELS 1468
            + +                     +L  + +++R+  HE+E   +          +++++
Sbjct: 1765 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1824

Query: 1469 QAHEEAQRE----------------KLQREKLQREKDMLLAEAFS------------LKQ 1500
            Q  E+ ++E                KL+   LQ E +  +AE +             LK+
Sbjct: 1825 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKR 1884

Query: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLR 1545
            QLEE + +          L+ EL + +         +  +K +LR
Sbjct: 1885 QLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 56/280 (20%), Positives = 130/280 (46%), Gaps = 21/280 (7%)

Query: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 1311
            +E++ ++ + ++ QL+  L  AE+ R +  L  + L     EL S L+     G +A Q 
Sbjct: 1678 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE---ELASSLS-----GRNALQ- 1728

Query: 1312 LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEW 1371
                  E+ R E  + +L+ + +  +  ME M   V +A   +A +++ E+  + +  + 
Sbjct: 1729 -----DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ-QAEQLSNELATERSTAQ- 1781

Query: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKK 1431
              K E A ++++   K L+ +     E+E   K + +  +  L+A   + +  ++Q  ++
Sbjct: 1782 --KNESARQQLERQNKELRSKLH---EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1836

Query: 1432 CQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDML 1491
             Q  T  L+     L+   ++  +  K   ++  +  + +   ++ K Q E+ + E   +
Sbjct: 1837 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1896

Query: 1492 LAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQES 1531
             A    L+++L+E         ++V +L+++L+    QE+
Sbjct: 1897 NANRRKLQRELDEATESNEAMGREVNALKSKLRGPPPQET 1936


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score =  597 bits (1540), Expect = e-170
 Identities = 495/1757 (28%), Positives = 864/1757 (49%), Gaps = 279/1757 (15%)

Query: 342  AEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400
            A+  W     VW+   + GF  AS +K E+ +    +V V+L  +G  + V +DD++K N
Sbjct: 26   AQADWAAKRLVWVPSEKQGFEAAS-IKEEKGD----EVVVELVENGKKVTVGKDDIQKMN 80

Query: 401  APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460
             P   ++ED+A L  LNE+SVLH LR+RY + L++TY+G   +V+ P     +YSEK++ 
Sbjct: 81   PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140

Query: 461  MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520
            M+KG +R +M PHIYA+A TAYR+ML  R+DQSI+  G SG+GKT + + ++QYLA +A 
Sbjct: 141  MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200

Query: 521  I-SGNKVFSVEKWQALY------------TLLEAFGNSPTIINGNATRFSQILSLDFDQA 567
               G K  S+ +  +               +LEAFGN+ T+ N N++RF + + ++FD  
Sbjct: 201  SHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVT 260

Query: 568  GQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHL----NHLAENNV 623
            G +  A+I+T LLEK R  R+   E TF++FYY++A     +R++L L    N+   +N 
Sbjct: 261  GYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG 320

Query: 624  FGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAE 683
            F  +P A+ +E       F +   AM ++G S +EQ +   +++++  LG     KE   
Sbjct: 321  FVPIPAAQDDE------MFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKER-N 373

Query: 684  AGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGG--TLQRSTSFRQGPEESGLGDG 741
              +     +  AQK  +L+G ++ + + +I   + K G   +Q++ +  Q          
Sbjct: 374  TDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQ---------- 423

Query: 742  TGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGG 800
                  A   +E +A   Y  LF  +++ VN+AL  +     S + I+D  GF+  E   
Sbjct: 424  ------ADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVN- 476

Query: 801  SARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQ 860
                 SFE+LC NYT ++LQ+LF+   F+ E E Y+ E IE  F D              
Sbjct: 477  -----SFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFG------------ 519

Query: 861  ASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLH 920
               Q  +  + R +   G+L LL+EE   P A++ + +E+L +  G      K Q P   
Sbjct: 520  LDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHP---KFQKPKQL 576

Query: 921  SSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGS 980
              K    ++   H    V+YN + WL     +P   N   LL  S  K +++L+      
Sbjct: 577  KDKTEFSII---HYAGKVDYNASAWLT-KNMDPLNDNVTSLLNASSDKFVADLWKD---- 628

Query: 981  ATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSK 1040
                   I GL+  +++      S  KT   GM     +++    K Q+  L+ T++ + 
Sbjct: 629  ----VDRIVGLDQMAKMTESSLPSASKT-KKGMF----RTVGQLYKEQLGKLMTTLRNTT 679

Query: 1041 LHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSR 1100
             +FV C +P  E  +G+                             LD  L+  QLR + 
Sbjct: 680  PNFVRCIIPNHEKRSGK-----------------------------LDAFLVLEQLRCNG 710

Query: 1101 LLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEK 1160
            +L+ +R+ RQG+P+ +VF EFR+R+++LA +   K       +D ++A   +++ L+L+ 
Sbjct: 711  VLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-----FMDGKQACILMIKALELDP 765

Query: 1161 SSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRC 1220
            +   +G S++FFR G LA LEE+RD + +  +  FQA CRGYLAR+ F KR+ Q  A++ 
Sbjct: 766  NLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKV 825

Query: 1221 VQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNEL 1280
            +Q+N      +++W WW+LFT V+PL++V   EE+++ K++E+Q+ + + +KAE E  EL
Sbjct: 826  IQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKEL 885

Query: 1281 RLNSDRLESRISELTSE--LTDERNTGESASQLLDAETAERLRAEK-EMKELQTQYDALK 1337
                   E + S+LT E  L  E+   E+       E   RL A+K E++E+  + +A  
Sbjct: 886  -------EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARL 938

Query: 1338 KQMEVMEMEVMEARLIRAAE---INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEF- 1393
            ++ E    ++   R   A +   +  ++++++A  + +L+ E+   E     K+L+ E  
Sbjct: 939  EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ-KLQLEKVTAEAKI--KKLEDEIL 995

Query: 1394 --EDKLEVEQQNKRQLERRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
              +D+     + ++ LE R+ DL    A+ EE  + L +LK K + + +EL+   + L+ 
Sbjct: 996  VMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKK 1052

Query: 1449 QQVRNHELEKKQRRFDSELSQAHEE-----AQREKLQREKLQREKDMLLAEAFSLKQQLE 1503
            ++    ELEK +R+ + + S  HE+     AQ  +L+ +  ++E+++  A A  L  ++ 
Sbjct: 1053 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA-RLDDEIA 1111

Query: 1504 EKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDL----EAKVKDQEEELD 1559
            +K+  +    +K+  LE  + D+      + A+  K +KQ RDL    EA   + E+ LD
Sbjct: 1112 QKNNAL----KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1167

Query: 1560 ------------EQAGTI--QMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1605
                        EQ  T+  + L++     E +++ MRQ H++ +E   E++E+ +++ +
Sbjct: 1168 STATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA-K 1226

Query: 1606 KKLKQMEVQLEEEYED-----------KQKVLREKRELEGKL--------------ATLS 1640
              L + +  LE+E  D           KQ+V  +K++LE ++              A L+
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286

Query: 1641 DQVNRRDFESEK-------------RLRKDLKRTKALLADAQLML--------------- 1672
            D+V++   E E              +L KD+    + L D Q +L               
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346

Query: 1673 ----------DHLKNSAPSKR-----------EIAQLKNQLEESEFTCAAAVKARKAMEV 1711
                      D L     +K+           +++  K +L++   T  A  + +K  + 
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1406

Query: 1712 EIEDLHLQIDDIAKAKTALEEQLSRLQRE----------KNEIQNRLEEDQEDMNELMKK 1761
            EIE+L  Q ++ A A   LE+  +RLQ+E          + ++ + LE+ Q   ++L+ +
Sbjct: 1407 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1466

Query: 1762 HK-----------AAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS 1810
             K            A A+A     +   L   LEEA + K+EL+   + L++++E L  S
Sbjct: 1467 EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSS 1526

Query: 1811 MVDKSL-VSRQEAKIRELETRLEFERTQVKRLESLAS-------RLKENMEKLTEERDQR 1862
              D    V   E   R LET++E  +TQ++ LE           RL+ NM+ L  + ++ 
Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1586

Query: 1863 IAAENREKEQNKR-LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQAD 1921
            + A + + E+ +R LQRQL + + E+ +  ++ A A+  K +LE DL+ LE    S    
Sbjct: 1587 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1646

Query: 1922 LKLAFKRIGDLQAAIED 1938
             + A K++  LQA ++D
Sbjct: 1647 REEAIKQLRKLQAQMKD 1663



 Score =  231 bits (589), Expect = 5e-60
 Identities = 189/738 (25%), Positives = 372/738 (50%), Gaps = 61/738 (8%)

Query: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNELRL 1282
            N+ KNK   +     L   +R L + +   E  + K E ++Q+L+SK    E+ R EL  
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1287

Query: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328
               +L++ +  +T  L +                   +   +LL  ET ++L    ++++
Sbjct: 1288 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1347

Query: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKR 1388
            L+ + ++L+ Q++  EME  +      + +N ++ D                    +KK+
Sbjct: 1348 LEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSD--------------------SKKK 1386

Query: 1389 LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
            LQ +F   +E  ++ K++ ++ + +L    EE   A  +L+K   RL  EL D  + L+ 
Sbjct: 1387 LQ-DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1445

Query: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
            Q+     LEKKQR+FD  L++    + +   +R++ + E      +A SL + LEE    
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1505

Query: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
                 +    L+AE++D+ S +     ++ +++K  R LE ++++ + +L+E    +Q  
Sbjct: 1506 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1565

Query: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
            E AKLRLE+ M+ ++    +++++RDE+ EE R+  Q++L + E +LE+E + +      
Sbjct: 1566 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1625

Query: 1629 KRELEGKLATL---SDQVNRRDFESEKRLRK---DLKRTKALLADAQLMLDHLKNSA-PS 1681
            K++LEG L  L   +D   +   E+ K+LRK    +K  +  L DA+   D +  +A  +
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685

Query: 1682 KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
            +++   L+  L + +   AAA +ARK  ++E E+L  ++      + AL+++  RL+   
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745

Query: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
             +++  LEE+Q +M  +  + + A  QA +   ++   ++  ++    +Q+L+ + + L+
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1805

Query: 1802 SQVEFLEQSMVD--KSLVSRQEAKIRELETRLEFE-RTQVKRLESLASRLKENMEKLTEE 1858
            S++  +E ++    KS ++  EAKI +LE ++E E R +    +SL  + K+  E L + 
Sbjct: 1806 SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV 1865

Query: 1859 RDQRIAAENREKEQN------KRLQRQLRDTKEEMGELARKEAEASRKKHELEMD--LES 1910
             D+R  AE  +++        K+L+RQL + +EE      +   A+R+K + E+D   ES
Sbjct: 1866 EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE-----SQRINANRRKLQRELDEATES 1920

Query: 1911 LEAANQSLQADLKLAFKR 1928
             EA  + + A LK   +R
Sbjct: 1921 NEAMGREVNA-LKSKLRR 1937



 Score =  173 bits (438), Expect = 2e-42
 Identities = 185/813 (22%), Positives = 352/813 (43%), Gaps = 137/813 (16%)

Query: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL-- 1311
            EQI +   +I +L+ +L K E+E   L+    RL+  I++  + L   R      S L  
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEE---LQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132

Query: 1312 -LDAETAERLRAEKEMKELQTQYDALKKQME------VMEMEVMEARLIRAAEINGEVDD 1364
             LD+E A R +AEK+ ++L  + +ALK ++E        + E+   R      +   +D+
Sbjct: 1133 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192

Query: 1365 DDAGGE-----WRLKYERAVRE--------------VDFTKKRLQQEFED---------- 1395
            +    E      R K+ +AV E              +D  K+ L++E  D          
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1252

Query: 1396 -KLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRL------------------- 1435
             K EVE + K++LE ++ +LQ+   + +RA  +L  K  +L                   
Sbjct: 1253 AKQEVEHK-KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI 1311

Query: 1436 ---------TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQR 1486
                     +++LQDT+  L+ +  +   +  K R+ + E +   ++   E   ++ L+R
Sbjct: 1312 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1371

Query: 1487 EKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1546
                L  +    K++L++    +    +     + E+++++ Q  +  A+  K++K    
Sbjct: 1372 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431

Query: 1547 LEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQK 1606
            L+ ++ D   +LD Q   +  LE+ + + +  +   +   SK  + RD    EAR+   K
Sbjct: 1432 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1491

Query: 1607 KLKQMEVQLEEEYEDKQKVLREKRELEGKLATL---SDQVNRRDFESEKRLR-------- 1655
             L      LEE  E K+++ R  + L+ ++  L    D V +   E EK  R        
Sbjct: 1492 ALSLARA-LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1550

Query: 1656 -----KDLKRTKALLADAQLMLD--------------------HLKNSAPSKREIAQLKN 1690
                 ++L+       DA+L L+                    + +     +R++ + + 
Sbjct: 1551 MKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET 1610

Query: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750
            +LE+     A A  A+K +E +++DL LQ D   K +    +QL +LQ +  + Q  LE+
Sbjct: 1611 ELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670

Query: 1751 DQEDMNELM---KKHKAAVAQASRDLAQINDLQAQLEEANK----EKQELQEKLQALQSQ 1803
             +   +E+    K+++        DL Q+ +  A  E A K    EK+EL E+L +  S 
Sbjct: 1671 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1730

Query: 1804 VEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQR 1862
               L+          R EA+I +LE  LE E+  ++ +     +  +  E+L+ E   +R
Sbjct: 1731 RNALQDEK------RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1784

Query: 1863 IAAENRE--KEQNKRLQRQLRDTKEEM---------GELARKEAEASRKKHELEMDLESL 1911
              A+  E  ++Q +R  ++LR    EM           +A  EA+ ++ + ++E +    
Sbjct: 1785 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREK 1844

Query: 1912 EAANQSLQADLKLAFKRIGDLQAAIEDEMESDE 1944
            +AA +SL    K   K++ ++   +EDE +  E
Sbjct: 1845 QAATKSL----KQKDKKLKEILLQVEDERKMAE 1873


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score =  597 bits (1538), Expect = e-170
 Identities = 462/1691 (27%), Positives = 838/1691 (49%), Gaps = 194/1691 (11%)

Query: 342  AEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400
            A+  W     VW+   + GF  AS +K E+ +    +V V+L  +G  + V +DD++K N
Sbjct: 26   AQADWAAKRLVWVPSEKQGFEAAS-IKEEKGD----EVVVELVENGKKVTVGKDDIQKMN 80

Query: 401  APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460
             P   ++ED+A L  LNE+SVLH LR+RY + L++TY+G   +V+ P     +YSEK++ 
Sbjct: 81   PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140

Query: 461  MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520
            M+KG +R +M PHIYA+A TAYR+ML  R+DQSI+  G SG+GKT + + ++QYLA +A 
Sbjct: 141  MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200

Query: 521  I-SGNKVFSVEKWQAL------------YTLLEAFGNSPTIINGNATRFSQILSLDFDQA 567
               G K  S+ +  +               +LEAFGN+ T+ N N++RF + + ++FD  
Sbjct: 201  SHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVT 260

Query: 568  GQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHL----NHLAENNV 623
            G +  A+I+T LLEK R  R+   E TF++FYY++A     +R++L L    N+   +N 
Sbjct: 261  GYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG 320

Query: 624  FGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAE 683
            F  +P A+ +E       F +   AM ++G S +EQ +   +++++  LG     KE   
Sbjct: 321  FVPIPAAQDDE------MFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKE-RN 373

Query: 684  AGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGG--TLQRSTSFRQGPEESGLGDG 741
              +     +  AQK  +L+G ++ + + +I   + K G   +Q++ +             
Sbjct: 374  TDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT------------- 420

Query: 742  TGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGG 800
               K  A   +E +A   Y  LF  +++ VN+AL  +     S + I+D  GF+  E   
Sbjct: 421  ---KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVN- 476

Query: 801  SARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQ 860
                 SFE+LC NYT ++LQ+LF+   F+ E E Y+ E IE  F D              
Sbjct: 477  -----SFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF------------G 519

Query: 861  ASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLH 920
               Q  +  + R +   G+L LL+EE   P A++ + +E+L +  G      K Q P   
Sbjct: 520  LDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG---SHPKFQKPKQL 576

Query: 921  SSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGS 980
              K    ++   H    V+YN + WL     +P   N   LL  S  K +++L+      
Sbjct: 577  KDKTEFSII---HYAGKVDYNASAWLT-KNMDPLNDNVTSLLNASSDKFVADLWKD---- 628

Query: 981  ATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSK 1040
                   I GL+  +++      S  KT   GM     +++    K Q+  L+ T++ + 
Sbjct: 629  ----VDRIVGLDQMAKMTESSLPSASKT-KKGMF----RTVGQLYKEQLGKLMTTLRNTT 679

Query: 1041 LHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSR 1100
             +FV C +P  E  +G                             +LD  L+  QLR + 
Sbjct: 680  PNFVRCIIPNHEKRSG-----------------------------KLDAFLVLEQLRCNG 710

Query: 1101 LLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEK 1160
            +L+ +R+ RQG+P+ +VF EFR+R+++LA +   K       +D ++A   +++ L+L+ 
Sbjct: 711  VLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-----FMDGKQACILMIKALELDP 765

Query: 1161 SSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRC 1220
            +   +G S++FFR G LA LEE+RD + +  +  FQA CRGYLAR+ F KR+ Q  A++ 
Sbjct: 766  NLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKV 825

Query: 1221 VQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNEL 1280
            +Q+N      +++W WW+LFT V+PL++V   EE+++ K++E+Q+ + + +KAE E  E 
Sbjct: 826  IQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKE- 884

Query: 1281 RLNSDRLESRISELTSE--LTDERNTGESASQLLDAETAERLRAEK-EMKELQTQYDALK 1337
                  LE + S+LT E  L  E+   E+       E   RL A+K E++E+  + +A  
Sbjct: 885  ------LEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARL 938

Query: 1338 KQMEVMEMEVMEARLIRA---AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQE-- 1392
            ++ E    ++   R   A    ++  ++++++A  + +L+ E+   E     K+L+ E  
Sbjct: 939  EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ-KLQLEKVTAEAKI--KKLEDEIL 995

Query: 1393 -FEDKLEVEQQNKRQLERRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
              +D+     + ++ LE R+ DL    A+ EE  + L +LK K + + +EL+   + L+ 
Sbjct: 996  VMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKK 1052

Query: 1449 QQVRNHELEKKQRRFDSELSQAHE-----EAQREKLQREKLQREKDMLLAEAFSLKQQLE 1503
            ++    ELEK +R+ + + S  HE     +AQ  +L+ +  ++E+++  A A  L  ++ 
Sbjct: 1053 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA-RLDDEIA 1111

Query: 1504 EKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAG 1563
            +K+  +    +K+  LE  + D+      + A+  K +KQ RDL  +++  + EL++   
Sbjct: 1112 QKNNAL----KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1167

Query: 1564 TIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY---- 1619
            +    ++ + + E E+  +++   +E  S + +V+E RQ   + ++++  QLE+      
Sbjct: 1168 STATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA 1227

Query: 1620 ---EDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLK 1676
               ++KQ + +E  +L G+L  L  Q  +     +K+L   ++  ++  +D +     L 
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLG-QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286

Query: 1677 NSAPS-KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1735
            +     + E+  +   L E+E       K   ++  +++D    + +  + K  +  +L 
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346

Query: 1736 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1795
            +L+ E+N +Q++L+E+ E    L +       Q S    ++ D  + +E   + K+  Q+
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1406

Query: 1796 KLQALQSQVEFLEQSMVDK--SLVSRQEAKIRELETRLEFERTQVKRLE-------SLAS 1846
            +++ L  Q E  + +  DK     +R + ++ +L   L+ +R  V  LE        L +
Sbjct: 1407 EIENLTQQYE-EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465

Query: 1847 RLKENMEKLTEERDQRIAAENREK---------------EQNKRLQRQLRDTKEEMGELA 1891
              K    K  +ERD R  AE REK               E  + L+R  +  K EM +L 
Sbjct: 1466 EEKNISSKYADERD-RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLV 1524

Query: 1892 RKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINS 1951
              + +  +  HELE    +LE   + ++  L+   +   +LQA  + ++  + N   +  
Sbjct: 1525 SSKDDVGKNVHELEKSKRALETQMEEMKTQLE---ELEDELQATEDAKLRLEVNMQALKG 1581

Query: 1952 EGDSDVDSELE 1962
            + + D+ +  E
Sbjct: 1582 QFERDLQARDE 1592



 Score =  231 bits (588), Expect = 7e-60
 Identities = 187/730 (25%), Positives = 367/730 (50%), Gaps = 60/730 (8%)

Query: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNELRL 1282
            N+ KNK   +     L   +R L + +   E  + K E ++Q+L+SK    E+ R EL  
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1287

Query: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328
               +L++ +  +T  L +                   +   +LL  ET ++L    ++++
Sbjct: 1288 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1347

Query: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKR 1388
            L+ + ++L+ Q++  EME  +      + +N ++ D                    +KK+
Sbjct: 1348 LEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSD--------------------SKKK 1386

Query: 1389 LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
            LQ +F   +E  ++ K++ ++ + +L    EE   A  +L+K   RL  EL D  + L+ 
Sbjct: 1387 LQ-DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1445

Query: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
            Q+     LEKKQR+FD  L++    + +   +R++ + E      +A SL + LEE    
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1505

Query: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
                 +    L+AE++D+ S +     ++ +++K  R LE ++++ + +L+E    +Q  
Sbjct: 1506 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1565

Query: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
            E AKLRLE+ M+ ++    +++++RDE+ EE R+  Q++L + E +LE+E + +      
Sbjct: 1566 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1625

Query: 1629 KRELEGKLATL---SDQVNRRDFESEKRLRK---DLKRTKALLADAQLMLDHLKNSAPSK 1682
            K++LEG L  L   +D   +   E+ K+LRK    +K  +  L DA+   D +  +A   
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685

Query: 1683 REIAQ-LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
             + A+ L+  L + +   AAA +ARK  ++E E+L  ++      + AL+++  RL+   
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745

Query: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
             +++  LEE+Q +M  +  + + A  QA +   ++   ++  ++    +Q+L+ + + L+
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1805

Query: 1802 SQVEFLEQSMVDK--SLVSRQEAKIRELETRLEFE-RTQVKRLESLASRLKENMEKLTEE 1858
            S++  +E ++  K  S ++  EAKI +LE ++E E R +    +SL  + K+  E L + 
Sbjct: 1806 SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV 1865

Query: 1859 RDQRIAAENREKEQNK------RLQRQLRDTKEEMGELARKEAEASRKKHELEMD--LES 1910
             D+R  AE  +++  K      +L+RQL + +EE      +   A+R+K + E+D   ES
Sbjct: 1866 EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE-----SQRINANRRKLQRELDEATES 1920

Query: 1911 LEAANQSLQA 1920
             EA  + + A
Sbjct: 1921 NEAMGREVNA 1930



 Score =  179 bits (455), Expect = 2e-44
 Identities = 197/856 (23%), Positives = 373/856 (43%), Gaps = 62/856 (7%)

Query: 1180 LEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKL 1239
            LEEQ +E+ +    L         A    KK + + L +      + K + + +     L
Sbjct: 962  LEEQLEEEEAARQKL---QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1018

Query: 1240 FTTVRPLIEVQLSEEQIRNKDEE-IQQLRSKLEKAEKERNEL-----RLNSDR------- 1286
             T +    E   +  +++NK E  I +L  +L+K EK R EL     +L  D        
Sbjct: 1019 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI 1078

Query: 1287 --LESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQM---- 1340
              L+++I+EL  +L  +    ++A   LD E A++  A K+++EL+     L++ +    
Sbjct: 1079 ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1138

Query: 1341 ------EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE 1394
                  E  + ++ E       E+   +D      E R K E+   EV   KK L +E  
Sbjct: 1139 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ---EVTVLKKALDEETR 1195

Query: 1395 DKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNH 1454
                  Q+ +++  + + +L    E+ +RA   L K  Q L  E  D    L        
Sbjct: 1196 SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1255

Query: 1455 ELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQ 1514
            E+E K+++ ++++ +   +    +  R +L  +   L  E  S+   L E +       +
Sbjct: 1256 EVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1315

Query: 1515 KVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLR 1574
             V SL ++LQD      ++      V  +LR LE +    +++LDE+    Q LE+    
Sbjct: 1316 DVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIST 1375

Query: 1575 LEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEG 1634
            L +++   ++   ++  S  E +EE ++  QK+++ +  Q EE+     K+ + K  L+ 
Sbjct: 1376 LNIQLSDSKKK-LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ 1434

Query: 1635 KLATLS-DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLE 1693
            +L  L  D  N+R   S   L K  ++   LLA+ +    ++ +    +R+ A+ + + +
Sbjct: 1435 ELDDLVVDLDNQRQLVSN--LEKKQRKFDQLLAEEK----NISSKYADERDRAEAEAREK 1488

Query: 1694 ESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE 1753
            E++     A+   +A+E  +E           AK  LE     L+ E  ++ +  ++  +
Sbjct: 1489 ETK-----ALSLARALEEALE-----------AKEELERTNKMLKAEMEDLVSSKDDVGK 1532

Query: 1754 DMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD 1813
            +++EL K  +A   Q      Q+ +L+ +L+     K  L+  +QAL+ Q E   Q+  +
Sbjct: 1533 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1592

Query: 1814 KSLVSRQEAK--IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871
            ++   R++ +  + E ET LE ER Q     +   +L+ +++ L  + D  I       +
Sbjct: 1593 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652

Query: 1872 QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLA--FKRI 1929
            Q ++LQ Q++D + E+ +      E      E E   +SLEA    LQ DL  A   ++ 
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1712

Query: 1930 GDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLK 1989
             DL+   ++E+  +    L       D    LE R+  ++  L + +G  +A SD     
Sbjct: 1713 ADLE---KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769

Query: 1990 SSSPTSYWKSLAPDRS 2005
            +         LA +RS
Sbjct: 1770 TQQAEQLSNELATERS 1785



 Score =  173 bits (438), Expect = 2e-42
 Identities = 185/813 (22%), Positives = 352/813 (43%), Gaps = 137/813 (16%)

Query: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL-- 1311
            EQI +   +I +L+ +L K E+E   L+    RL+  I++  + L   R      S L  
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEE---LQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132

Query: 1312 -LDAETAERLRAEKEMKELQTQYDALKKQME------VMEMEVMEARLIRAAEINGEVDD 1364
             LD+E A R +AEK+ ++L  + +ALK ++E        + E+   R      +   +D+
Sbjct: 1133 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192

Query: 1365 DDAGGE-----WRLKYERAVRE--------------VDFTKKRLQQEFED---------- 1395
            +    E      R K+ +AV E              +D  K+ L++E  D          
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1252

Query: 1396 -KLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRL------------------- 1435
             K EVE + K++LE ++ +LQ+   + +RA  +L  K  +L                   
Sbjct: 1253 AKQEVEHK-KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI 1311

Query: 1436 ---------TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQR 1486
                     +++LQDT+  L+ +  +   +  K R+ + E +   ++   E   ++ L+R
Sbjct: 1312 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1371

Query: 1487 EKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1546
                L  +    K++L++    +    +     + E+++++ Q  +  A+  K++K    
Sbjct: 1372 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431

Query: 1547 LEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQK 1606
            L+ ++ D   +LD Q   +  LE+ + + +  +   +   SK  + RD    EAR+   K
Sbjct: 1432 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1491

Query: 1607 KLKQMEVQLEEEYEDKQKVLREKRELEGKLATL---SDQVNRRDFESEKRLR-------- 1655
             L      LEE  E K+++ R  + L+ ++  L    D V +   E EK  R        
Sbjct: 1492 ALSLARA-LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1550

Query: 1656 -----KDLKRTKALLADAQLMLD--------------------HLKNSAPSKREIAQLKN 1690
                 ++L+       DA+L L+                    + +     +R++ + + 
Sbjct: 1551 MKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET 1610

Query: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750
            +LE+     A A  A+K +E +++DL LQ D   K +    +QL +LQ +  + Q  LE+
Sbjct: 1611 ELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670

Query: 1751 DQEDMNELM---KKHKAAVAQASRDLAQINDLQAQLEEANK----EKQELQEKLQALQSQ 1803
             +   +E+    K+++        DL Q+ +  A  E A K    EK+EL E+L +  S 
Sbjct: 1671 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1730

Query: 1804 VEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQR 1862
               L+          R EA+I +LE  LE E+  ++ +     +  +  E+L+ E   +R
Sbjct: 1731 RNALQDEK------RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1784

Query: 1863 IAAENRE--KEQNKRLQRQLRDTKEEM---------GELARKEAEASRKKHELEMDLESL 1911
              A+  E  ++Q +R  ++LR    EM           +A  EA+ ++ + ++E +    
Sbjct: 1785 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREK 1844

Query: 1912 EAANQSLQADLKLAFKRIGDLQAAIEDEMESDE 1944
            +AA +SL    K   K++ ++   +EDE +  E
Sbjct: 1845 QAATKSL----KQKDKKLKEILLQVEDERKMAE 1873



 Score =  120 bits (301), Expect = 1e-26
 Identities = 132/583 (22%), Positives = 263/583 (45%), Gaps = 60/583 (10%)

Query: 1174 AGTLARLEE--QRDEQTSRNLTL-FQAACRGYLARQHFKKRKIQDLAIRCV----QKNIK 1226
            A T+  LEE  +R ++   NLT  ++     Y   +  K R  Q+L    V    Q+ + 
Sbjct: 1391 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1450

Query: 1227 KNKGVKDWPWWKLFTTVRPLI-----EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELR 1281
             N   K   + +L    + +      E   +E + R K+ +   L   LE+A + + EL 
Sbjct: 1451 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1510

Query: 1282 LNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQME 1341
              +  L++ + +L S   D    G++  +L           EK  + L+TQ + +K Q+E
Sbjct: 1511 RTNKMLKAEMEDLVSSKDD---VGKNVHEL-----------EKSKRALETQMEEMKTQLE 1556

Query: 1342 VMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ 1401
             +E E+                 +DA    +L+ E  ++ +   K + +++ + + E  +
Sbjct: 1557 ELEDELQAT--------------EDA----KLRLEVNMQAL---KGQFERDLQARDEQNE 1595

Query: 1402 QNKRQLERRLGDLQADSEES--QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKK 1459
            + +RQL+R+L + + + E+   QRAL    KK  +L  +L+D +L  +       E  K+
Sbjct: 1596 EKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDLKDLELQADSAIKGREEAIKQ 1653

Query: 1460 QRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL 1519
             R+  +++     E +  +  R+++         +A SL+  L +   D+A   +     
Sbjct: 1654 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1713

Query: 1520 EAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEM 1579
            + E ++++ + +   +    ++ + R LEA++   EEEL+E+ G ++ +     +   + 
Sbjct: 1714 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1773

Query: 1580 ERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE-EYEDKQKVLREKRELEGKLAT 1638
            E++    + E  S  ++ E ARQ  +++ K++  +L E E   K K       LE K+A 
Sbjct: 1774 EQLSNELATE-RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1832

Query: 1639 LSDQVNRRDFESE---KRLRKDLKRTKALL---ADAQLMLDHLKNSA-PSKREIAQLKNQ 1691
            L +QV +   E +   K L++  K+ K +L    D + M +  K  A      + QLK Q
Sbjct: 1833 LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1892

Query: 1692 LEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734
            LEE+E         R+ ++ E+++     + + +   AL+ +L
Sbjct: 1893 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 96/465 (20%), Positives = 190/465 (40%), Gaps = 106/465 (22%)

Query: 1179 RLEEQRDEQTSRNLTLFQAACRGYLARQHFK------KRKIQDLAIRC--VQKNI---KK 1227
            R E +  E+ ++ L+L +A      A++  +      K +++DL      V KN+   +K
Sbjct: 1480 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1539

Query: 1228 NKGVKDWPWWKLFTTVRPLI-EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDR 1286
            +K   +    ++ T +  L  E+Q +E+     +  +Q L+ + E+  + R+E      R
Sbjct: 1540 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1599

Query: 1287 -LESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDA---------- 1335
             L+ ++ E  +EL DER     A+       A + + E ++K+L+ Q D+          
Sbjct: 1600 QLQRQLHEYETELEDERKQRALAA-------AAKKKLEGDLKDLELQADSAIKGREEAIK 1652

Query: 1336 ----LKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGG-----------EWRLKYERAVR 1380
                L+ QM+  + E+ +AR  R  EI     +++              E     ERA +
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRD-EIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1711

Query: 1381 EVDFTKKRLQQEFEDKLEVE---QQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
            + D  K+ L +E    L      Q  KR+LE R+  L+ + EE Q  ++ +  + ++ T 
Sbjct: 1712 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1771

Query: 1438 ELQDT-------------------KLHLEGQQVRN--HELEKKQRR--------FDSELS 1468
            + +                     +L  + +++R+  HE+E   +          +++++
Sbjct: 1772 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1831

Query: 1469 QAHEEAQRE----------------KLQREKLQREKDMLLAEAFS------------LKQ 1500
            Q  E+ ++E                KL+   LQ E +  +AE +             LK+
Sbjct: 1832 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKR 1891

Query: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLR 1545
            QLEE + +          L+ EL + +         +  +K +LR
Sbjct: 1892 QLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 56/280 (20%), Positives = 130/280 (46%), Gaps = 21/280 (7%)

Query: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 1311
            +E++ ++ + ++ QL+  L  AE+ R +  L  + L     EL S L+     G +A Q 
Sbjct: 1685 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE---ELASSLS-----GRNALQ- 1735

Query: 1312 LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEW 1371
                  E+ R E  + +L+ + +  +  ME M   V +A   +A +++ E+  + +  + 
Sbjct: 1736 -----DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ-QAEQLSNELATERSTAQ- 1788

Query: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKK 1431
              K E A ++++   K L+ +     E+E   K + +  +  L+A   + +  ++Q  ++
Sbjct: 1789 --KNESARQQLERQNKELRSKLH---EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1843

Query: 1432 CQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDML 1491
             Q  T  L+     L+   ++  +  K   ++  +  + +   ++ K Q E+ + E   +
Sbjct: 1844 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1903

Query: 1492 LAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQES 1531
             A    L+++L+E         ++V +L+++L+    QE+
Sbjct: 1904 NANRRKLQRELDEATESNEAMGREVNALKSKLRGPPPQET 1943


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score =  588 bits (1516), Expect = e-167
 Identities = 457/1719 (26%), Positives = 852/1719 (49%), Gaps = 169/1719 (9%)

Query: 342  AEEAWNETEKVWLVH-RDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400
            A+  W   + VW+   + GF  AS LK E   + E  + V+L  +G  + V++DD++K N
Sbjct: 22   AQADWAAKKLVWVPSDKSGFEPAS-LKEE---VGEEAI-VELVENGKKVKVNKDDIQKMN 76

Query: 401  APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460
             P   ++ED+A L  LNE+SVLH L++RY + L++TY+G   +V+ P     +YSE+++ 
Sbjct: 77   PPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVE 136

Query: 461  MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520
            M+KG +R +M PHIYA+  TAYR+M+  R+DQSI+  G SG+GKT + + ++QYLA +A 
Sbjct: 137  MYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVAS 196

Query: 521  ISGNKVFSVEKWQALYT---LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQT 577
               +K    E  + L     +LEAFGN+ T+ N N++RF + + ++FD  G +  A+I+T
Sbjct: 197  SHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIET 256

Query: 578  MLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQK 637
             LLEK R  R+   E TF++FYYLL+     L+T+L L    +        +  P ++ K
Sbjct: 257  YLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDK 316

Query: 638  AAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQK 697
                F +   AM+++GI  +EQ     +++ +  LG     KE     +     +  AQK
Sbjct: 317  --DMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKER-NTDQASMPDNTAAQK 373

Query: 698  AAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSALECLEGM 755
             ++LLG ++ + +  I   + K G   +Q++ +  Q                A   +E +
Sbjct: 374  VSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQ----------------ADFAIEAL 417

Query: 756  AAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASFEELCHNY 814
            A   Y  +F  LV  +N+AL  ++    S + I+D  GF+  +        SFE+LC NY
Sbjct: 418  AKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLN------SFEQLCINY 471

Query: 815  TQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTD 874
            T ++LQ+LF+   F+ E E Y+ E IE  F D        +  +++ +            
Sbjct: 472  TNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPP--------- 522

Query: 875  EARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHG 934
               G+L LL+EE   P A++ + +E++    G      K Q P     K    ++   H 
Sbjct: 523  ---GILALLDEECWFPKATDKSFVEKVMQEQGTHP---KFQKPKQLKDKADFCII---HY 573

Query: 935  TNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGG 994
               V+Y    WL     +P   N   LL  S  K +S L+  +     +    +AG+   
Sbjct: 574  AGKVDYKADEWL-MKNMDPLNDNIATLLHQSSDKFVSELW--KDVDRIIGLDQVAGM--- 627

Query: 995  SQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGW 1054
            S+ AL  A   RK     +  + K+ L          L+ T++ +  +FV C +P  E  
Sbjct: 628  SETALPGAFKTRKGMFRTVGQLYKEQLA--------KLMATLRNTNPNFVRCIIPNHEKK 679

Query: 1055 AGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPD 1114
            AG+                             LD  L+  QLR + +L+ +R+ RQG+P+
Sbjct: 680  AGK-----------------------------LDPHLVLDQLRCNGVLEGIRICRQGFPN 710

Query: 1115 HMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRA 1174
             +VF EFR+R+++L P+   K       +D ++A   +++ L+L+ +   +G S+VFFRA
Sbjct: 711  RVVFQEFRQRYEILTPNSIPKG-----FMDGKQACVLMIKALELDSNLYRIGQSKVFFRA 765

Query: 1175 GTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDW 1234
            G LA LEE+RD + +  +  FQA CRGYLAR+ F KR+ Q  A++ +Q+N      +++W
Sbjct: 766  GVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNW 825

Query: 1235 PWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISEL 1294
             WW+LFT V+PL++V   EE++  K+EE+ ++R K   AE    E+     +L +   +L
Sbjct: 826  QWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQL 885

Query: 1295 TSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIR 1354
              +L  E      A +L    TA++   E+   +L+ + +  +++ + ++ E  + +   
Sbjct: 886  QEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ-N 944

Query: 1355 AAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN------KRQLE 1408
              E+  +++++++  + +L+ E+       T+ +L++  E+++ +E QN      K+ LE
Sbjct: 945  IQELEEQLEEEESARQ-KLQLEKVT-----TEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998

Query: 1409 RRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDS 1465
             R+ +      + EE  ++L +LK K + +  +L++    L  ++ +  ELEK +R+ + 
Sbjct: 999  DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE---RLRREEKQRQELEKTRRKLEG 1055

Query: 1466 ELSQ-----AHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLE 1520
            + +      A  +AQ  +L+ +  ++E+++  A A  ++++  +K+M +    +K+  LE
Sbjct: 1056 DSTDLSDQIAELQAQIAELKMQLAKKEEELQAALA-RVEEEAAQKNMAL----KKIRELE 1110

Query: 1521 AELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1580
            +++ ++      + AS  K +KQ RDL  +++  + EL++   +    ++ + + E E+ 
Sbjct: 1111 SQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVN 1170

Query: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLS 1640
             +++T  +E ++ + +++E RQ   + ++++  QLE+    K  + + K+ LE +   L+
Sbjct: 1171 ILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELA 1230

Query: 1641 DQV-----NRRDFE-SEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKR-EIAQLKNQLE 1693
            ++V      + D E   K++   L+  +    + + +   L +     + E+  +   L 
Sbjct: 1231 NEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLS 1290

Query: 1694 ESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE 1753
            +S+   +   K   A+E +++D    + +  + K +L  +L +++ EKN  + +LEE++E
Sbjct: 1291 QSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEE 1350

Query: 1754 DMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD 1813
              + L K+     AQ +    ++ D    LE A + K++LQ+ L+ L SQ    + +  D
Sbjct: 1351 AKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGL-SQRHEEKVAAYD 1409

Query: 1814 K--SLVSRQEAKIRELETRLEFERTQV-------KRLESLASRLKENMEKLTEERDQRIA 1864
            K     +R + ++ +L   L+ +R          K+ + L +  K    K  EERD R  
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERD-RAE 1468

Query: 1865 AENREK---------------EQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLE 1909
            AE REK               EQ   L+R  +  + EM +L   + +  +  HELE    
Sbjct: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528

Query: 1910 SLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVK 1969
            +LE   + ++  L+   +   +LQA  + ++  + N   + ++ + D+    +++ +  K
Sbjct: 1529 ALEQQVEEMKTQLE---ELEDELQATEDAKLRLEVNLQAMKAQFERDLQGR-DEQSEEKK 1584

Query: 1970 SWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDE 2008
              L +     +A  +D   + S   +  K L  D  D E
Sbjct: 1585 KQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623



 Score =  213 bits (543), Expect = 1e-54
 Identities = 203/796 (25%), Positives = 388/796 (48%), Gaps = 96/796 (12%)

Query: 1221 VQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNE 1279
            V+ N++K K   +    +L   V+ L++ +   E  R K E ++Q+L+ K  + E+ R E
Sbjct: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270

Query: 1280 LRLNSDRLE--------------SRISELTSELTDERNTGESASQLLDAETAERLRAEKE 1325
            L     +L+              S+ S+LT + +   +  +   +LL  E  ++L    +
Sbjct: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330

Query: 1326 MKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFT 1385
            +K+++ + ++ ++Q+E  E E       + A ++ +V D                     
Sbjct: 1331 LKQVEDEKNSFREQLEEEE-EAKHNLEKQIATLHAQVAD--------------------- 1368

Query: 1386 KKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLH 1445
             K+  ++    LE  ++ KR+L++ L  L    EE   A  +L+K   RL  EL D  + 
Sbjct: 1369 MKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVD 1428

Query: 1446 LEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEK 1505
            L+ Q+     LEKKQ++FD  L++    + +   +R++ + E      +A SL + LEE 
Sbjct: 1429 LDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEA 1488

Query: 1506 DMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTI 1565
                A   +       E++D+ S +     S+ +++K  R LE +V++ + +L+E    +
Sbjct: 1489 MEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDEL 1548

Query: 1566 QMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKV 1625
            Q  E AKLRLE+ ++ M+    ++++ RDE+ EE ++   +++++ME +LE+E + +   
Sbjct: 1549 QATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMA 1608

Query: 1626 LREKRELEGKLATLS---DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDH-------- 1674
            +  +++LE  L  L    D  N+   E+ K+LRK     +A + D    LD         
Sbjct: 1609 VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK----LQAQMKDCMRELDDTRASREEI 1664

Query: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQI-DDIAKAKTALEEQ 1733
            L  +  +++++  ++ ++ + +   AAA +A++  + E ++L  +I +   K   ALEE+
Sbjct: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK 1724

Query: 1734 LSRLQREKNEIQNRLEEDQ---EDMNELMKKHKAAVAQASRDL------AQIND-LQAQL 1783
              RL+    +++  LEE+Q   E +N+ +KK    + Q + DL      AQ N+  + QL
Sbjct: 1725 -RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQL 1783

Query: 1784 EEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFE----RTQVK 1839
            E  NK   EL+ KLQ ++  V+        K+ ++  EAKI +LE +L+ E    +   K
Sbjct: 1784 ERQNK---ELKVKLQEMEGTVK-----SKYKASITALEAKIAQLEEQLDNETKERQAACK 1835

Query: 1840 RLESLASRLKENMEKLTEER---DQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAE 1896
            ++     +LK+ + ++ +ER   +Q     ++   + K+L+RQL + +EE      + A 
Sbjct: 1836 QVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEE-----AQRAN 1890

Query: 1897 ASRKK--HELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGD 1954
            ASR+K   ELE   E+ +A N+ + + LK   +R GDL   +   M            GD
Sbjct: 1891 ASRRKLQRELEDATETADAMNREV-SSLKNKLRR-GDLPFVVPRRMAR-------KGAGD 1941

Query: 1955 SDVDSELEDRVDGVKS 1970
               D E++ + DG ++
Sbjct: 1942 GS-DEEVDGKADGAEA 1956


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score =  581 bits (1497), Expect = e-165
 Identities = 444/1722 (25%), Positives = 839/1722 (48%), Gaps = 170/1722 (9%)

Query: 341  AAEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKA 399
            A +  W   + VW+   R GF  AS +K E  +    +V V+L  +G    V++DD++K 
Sbjct: 25   ATQADWTAKKLVWIPSERHGFEAAS-IKEERGD----EVMVELAENGKKAMVNKDDIQKM 79

Query: 400  NAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVM 459
            N P   ++ED+A L  LNE+SVLH L+ RY + L++TY+G   +V+ P     +YSE ++
Sbjct: 80   NPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENII 139

Query: 460  HMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIA 519
             M++G +R +M PHIYA++++AYR ML  R+DQSI+  G SG+GKT + + ++QYLA +A
Sbjct: 140  EMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVA 199

Query: 520  GI-SGNKVFSVE---KWQALYT--LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASA 573
                G K  ++    + Q L    +LE+FGN+ T+ N N++RF + + ++FD  G +  A
Sbjct: 200  SSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGA 259

Query: 574  SIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVF--GIVPLAK 631
            +I+T LLEK R  R+   E TF++FY LL+     L+++L L           G +P+  
Sbjct: 260  NIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPG 319

Query: 632  PEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFAR 691
             ++K      F +   AM ++G S +E  +   +++++   G     KE     +     
Sbjct: 320  QQDKDN----FQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKER-NTDQASMPE 374

Query: 692  HEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSAL 749
            +  AQK  +LLG ++ E + AI   + K G   +Q++ +  Q                A 
Sbjct: 375  NTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQ----------------AD 418

Query: 750  ECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASFE 808
              +E +A   Y  LF  LV  +N+AL  ++    S + I+D  GF+  E        SFE
Sbjct: 419  FAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELN------SFE 472

Query: 809  ELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVR 868
            +LC NYT ++LQ+LF+   F+ E E Y+ E IE  F D        +  +++ ++     
Sbjct: 473  QLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPP--- 529

Query: 869  SLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFL 928
                     G+L LL+EE   P A++ T +E+L    G      K Q P     K    +
Sbjct: 530  ---------GVLALLDEECWFPKATDKTFVEKLVQEQGSHS---KFQKPRQLKDKADFCI 577

Query: 929  LGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSI 988
            +   H    V+Y    WL     +P   N   LL  S  + ++ L+             I
Sbjct: 578  I---HYAGKVDYKADEWL-MKNMDPLNDNVATLLHQSSDRFVAELWKD--------VDRI 625

Query: 989  AGLE---GGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVH 1045
             GL+   G ++ A   A   +K     +  + K+SL          L+ T++ +  +FV 
Sbjct: 626  VGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLT--------KLMATLRNTNPNFVR 677

Query: 1046 CFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAM 1105
            C +P  E  AG+                             LD  L+  QLR + +L+ +
Sbjct: 678  CIIPNHEKRAGK-----------------------------LDPHLVLDQLRCNGVLEGI 708

Query: 1106 RMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCM 1165
            R+ RQG+P+ +VF EFR+R+++L P+   K       +D ++A E ++  L+L+ +   +
Sbjct: 709  RICRQGFPNRIVFQEFRQRYEILTPNAIPKG-----FMDGKQACERMIRALELDPNLYRI 763

Query: 1166 GLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNI 1225
            G S++FFRAG LA LEE+RD + +  +  FQA CRGYLAR+ F K++ Q  A++ +Q+N 
Sbjct: 764  GQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNC 823

Query: 1226 KKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSD 1285
                 ++ W WW++FT V+PL++V   EE+++ KDEE+ +++ K  K E E  E+     
Sbjct: 824  AAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQ 883

Query: 1286 RLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEM 1345
            +L    + L  +L  E      A ++     A++   E+ + +L+++ +  +++ ++++ 
Sbjct: 884  QLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQN 943

Query: 1346 EVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQE---FEDKLEVEQQ 1402
            E  + +     ++  ++D+++ G   +L+ E+   E     K++++E    ED+     +
Sbjct: 944  EKKKMQ-AHIQDLEEQLDEEE-GARQKLQLEKVTAEAKI--KKMEEEILLLEDQNSKFIK 999

Query: 1403 NKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRR 1462
             K+ +E R+ +  +   E +   + L K   +    + D +  L+ ++    ELEK +R+
Sbjct: 1000 EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059

Query: 1463 FDSELSQ-----AHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVV 1517
             D E +      A  +AQ ++L+ +  ++E+++  A A    + L + +       + V 
Sbjct: 1060 LDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNA-----LKVVR 1114

Query: 1518 SLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM 1577
             L+A++ ++      ++AS  K +KQ RDL  +++  + EL++   T    ++ + + E 
Sbjct: 1115 ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQ 1174

Query: 1578 EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLA 1637
            E+  +++   +E ++ + ++++ RQ     L+++  QLE+    K  + + K+ LE    
Sbjct: 1175 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234

Query: 1638 TLS------DQVNRRDFESEKRLRKDLKRTKALLADA-QLMLDHLKNSAPSKREIAQLKN 1690
             L+       QV        K+L   ++   A +++  +L ++  + ++  + E+  +  
Sbjct: 1235 ELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVST 1294

Query: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750
             LEE+E       K   ++E +++D    + +  + K  L  ++ +L+ EKN +Q + EE
Sbjct: 1295 LLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354

Query: 1751 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVE--FLE 1808
            ++E    L K+  A  +Q +    +++D    +E   + K++L +  +AL  ++E   L 
Sbjct: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1414

Query: 1809 QSMVDKSLVSRQEAKIRELETRLEFER-------TQVKRLESLASRLKENMEKLTEERDQ 1861
               ++K+  +R + ++ +L   L+ +R        + K+ + L +  K    +  EERD 
Sbjct: 1415 YDKLEKT-KNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD- 1472

Query: 1862 RIAAENREK---------------EQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEM 1906
            R  AE REK               E  +  +RQ +  + +M +L   + +  +  HELE 
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEK 1532

Query: 1907 DLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVD 1966
               +LE   + ++  L+   +   +LQA  + ++  + N   + ++ + D+ +  +++ +
Sbjct: 1533 SKRALEQQVEEMRTQLE---ELEDELQATEDAKLRLEVNMQAMKAQFERDLQTR-DEQNE 1588

Query: 1967 GVKSWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDE 2008
              K  L K     +A  +D   + +   +  K +  D  D E
Sbjct: 1589 EKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLE 1630



 Score =  228 bits (580), Expect = 6e-59
 Identities = 174/736 (23%), Positives = 373/736 (50%), Gaps = 58/736 (7%)

Query: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNK-DEEIQQLRSKLEKAEKERNELRL 1282
            N++KNK   +    +L   V+ L +V+   E  R K D ++Q+L +K+ + ++ R EL  
Sbjct: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE 1280

Query: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328
             + +L++ +  +++ L +    G              +   +LL  ET ++L     +++
Sbjct: 1281 KASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQ 1340

Query: 1329 LQTQYDALKKQMEVME--MEVMEARLI----RAAEINGEVDDDDAGGEWRLKYERAVREV 1382
            L+ + ++L++Q E  E   + +E +++    + A+   +VDDD             +  +
Sbjct: 1341 LEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLG----------TIESL 1390

Query: 1383 DFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 1442
            +  KK+L ++ E            L +RL       EE   A  +L+K   RL  EL D 
Sbjct: 1391 EEAKKKLLKDAE-----------ALSQRL-------EEKALAYDKLEKTKNRLQQELDDL 1432

Query: 1443 KLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQL 1502
             + L+ Q+     LEKKQ++FD  L++    + R   +R++ + E      +A SL + L
Sbjct: 1433 TVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARAL 1492

Query: 1503 EEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQA 1562
            EE       F ++   L A+++D+ S +     ++ +++K  R LE +V++   +L+E  
Sbjct: 1493 EEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELE 1552

Query: 1563 GTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDK 1622
              +Q  E AKLRLE+ M+ M+    +++++RDE+ EE ++   K+++++E +LE+E + +
Sbjct: 1553 DELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQR 1612

Query: 1623 QKVLREKRELEGKLATLSDQV---NRRDFESEKRLRK---DLKRTKALLADAQLMLDHL- 1675
               +  K+++E  L  L  Q+   N+   E  K+LRK    +K  +  L +A+   D + 
Sbjct: 1613 ALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIF 1672

Query: 1676 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1735
              S  S++++  L+ ++ + +   A++ +AR+  E E ++L  +I + A  K+AL ++  
Sbjct: 1673 AQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKR 1732

Query: 1736 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1795
            RL+    +++  LEE+Q +M  L  + +    Q     A++   ++  ++++  +Q+L+ 
Sbjct: 1733 RLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLER 1792

Query: 1796 KLQALQSQVEFLEQSMVD--KSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1853
            + + L+++++ LE ++    K+ +S  EAKI +LE +LE E  +      L  R ++ ++
Sbjct: 1793 QNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLK 1852

Query: 1854 KLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1913
            ++  + +      ++ KEQ ++   +++  K ++ E   +   A+  + +L+ +L+    
Sbjct: 1853 EIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATE 1912

Query: 1914 ANQSLQADLKLAFKRI 1929
            AN+ L  ++     R+
Sbjct: 1913 ANEGLSREVSTLKNRL 1928



 Score =  177 bits (450), Expect = 7e-44
 Identities = 170/792 (21%), Positives = 368/792 (46%), Gaps = 85/792 (10%)

Query: 1209 KKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS--EEQIRNKDEEIQQL 1266
            +K+ ++D    C  +  ++ +  K+         +R   EV +S  EE+++ +++  Q+L
Sbjct: 1000 EKKLMEDRIAECSSQLAEEEEKAKN------LAKIRNKQEVMISDLEERLKKEEKTRQEL 1053

Query: 1267 RSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEM 1326
                 K + E  +L+     L+++I EL  +L  +    + A    D ET  +  A K +
Sbjct: 1054 EKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVV 1113

Query: 1327 KELQTQYDALKKQMEV----------MEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYE 1376
            +ELQ Q   L++  E            + ++ E       E+   +D   A  E R K E
Sbjct: 1114 RELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKRE 1173

Query: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436
            + V E+   KK L++E ++     Q  +++    L +L    E+++R    L+K  Q L 
Sbjct: 1174 QEVAEL---KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLE 1230

Query: 1437 AELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF 1496
             + ++    ++  Q    E E K+++ D+++ + H +       R +L  +   L  E  
Sbjct: 1231 TDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290

Query: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQD----------------------------ISS 1528
            ++   LEE +     F +   SLE++LQD                            +  
Sbjct: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350

Query: 1529 QESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSK 1588
            Q+ ++E +   ++KQ+  L++++ D ++++D+  GTI+ LE+AK +L  + E + Q   +
Sbjct: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410

Query: 1589 EMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDF 1648
            +  + D+ +E+ +   Q++L  + V L+ + +    + +++++ +  LA     ++ R  
Sbjct: 1411 KALAYDK-LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAE-EKSISARYA 1468

Query: 1649 ESEKRLRKDL--KRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKAR 1706
            E   R   +   K TKAL   A+ + + L+     +R+  QL+  +E+            
Sbjct: 1469 EERDRAEAEAREKETKALSL-ARALEEALEAKEEFERQNKQLRADMED------------ 1515

Query: 1707 KAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAV 1766
              +    +D+   + ++ K+K ALE+Q+  ++ +  E+++ L+  ++    L    +A  
Sbjct: 1516 --LMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK 1573

Query: 1767 AQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEF-LEQSMVDKSLVSRQEAKIR 1825
            AQ  RDL      Q + E+  ++K+ L ++++ L++++E   +Q  +  +   + E  ++
Sbjct: 1574 AQFERDL------QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK 1627

Query: 1826 ELETRLEFERTQ----VKRLESLASRLKENMEKLTEERDQR--IAAENREKEQN-KRLQR 1878
            +LE ++E         +K+L  L +++K+   +L E R  R  I A+++E E+  K L+ 
Sbjct: 1628 DLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEA 1687

Query: 1879 QLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED 1938
            ++   +EE+    R    A +++ EL  ++ +  +   +L  + +    RI  L+  +E+
Sbjct: 1688 EILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEE 1747

Query: 1939 EMESDENEDLIN 1950
            E     N +L+N
Sbjct: 1748 E---QSNMELLN 1756



 Score =  115 bits (287), Expect = 6e-25
 Identities = 122/584 (20%), Positives = 261/584 (44%), Gaps = 60/584 (10%)

Query: 1175 GTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRK------IQDLAI-----RCVQK 1223
            GT+  LEE + +       L Q      LA    +K K      + DL +     R V  
Sbjct: 1385 GTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVAS 1444

Query: 1224 NI-KKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRL 1282
            N+ KK K        +   + R   E   +E + R K+ +   L   LE+A + + E   
Sbjct: 1445 NLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFER 1504

Query: 1283 NSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEV 1342
             + +L + + +L S   D    G++  +L  ++ A     E++++E++TQ + L+ +++ 
Sbjct: 1505 QNKQLRADMEDLMSSKDD---VGKNVHELEKSKRA----LEQQVEEMRTQLEELEDELQA 1557

Query: 1343 MEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQ 1402
             E    +A+L    E+N +                        K + +++ + + E  ++
Sbjct: 1558 TE----DAKL--RLEVNMQA----------------------MKAQFERDLQTRDEQNEE 1589

Query: 1403 NKRQLERRLGDLQADSEES--QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQ 1460
             KR L +++ +L+A+ E+   QRAL    KK  ++  +L+D +  +E       E+ K+ 
Sbjct: 1590 KKRLLIKQVRELEAELEDERKQRALAVASKK--KMEIDLKDLEAQIEAANKARDEVIKQL 1647

Query: 1461 RRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLE 1520
            R+  +++     E +  +  R+++  +      +  SL+ ++ +   ++A   +     E
Sbjct: 1648 RKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAE 1707

Query: 1521 AELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1580
             E  +++ + +   +  + +  + R LEA++   EEEL+E+   +++L     +  ++++
Sbjct: 1708 QERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVD 1767

Query: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE-EYEDKQKVLREKRELEGKLATL 1639
             +    + E  S  ++ + ARQ  +++ K+++ +L+E E   K K       LE K+  L
Sbjct: 1768 TLNAELAAE-RSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQL 1826

Query: 1640 SDQVNRRDFESE------KRLRKDLKRTKALLADAQLMLDHLKNSAP-SKREIAQLKNQL 1692
             +Q+ +   E        +R  K LK     + D +   D  K     +   + QLK QL
Sbjct: 1827 EEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQL 1886

Query: 1693 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSR 1736
            EE+E     A  +R+ ++ E++D     + +++  + L+ +L R
Sbjct: 1887 EEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score =  531 bits (1369), Expect = e-150
 Identities = 480/1777 (27%), Positives = 828/1777 (46%), Gaps = 274/1777 (15%)

Query: 346  WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404
            W     VW+     GF  A+ L+ E     E +  V+L   G  L +  D +++ N P  
Sbjct: 50   WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104

Query: 405  DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464
             + ED+A L  LNE+SVLH LR+RY + L++TY+G   +V+ P     +Y+E ++ M++G
Sbjct: 105  SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164

Query: 465  CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523
             +R ++ PH+YAV + AYR+ML  R+DQSI+  G SG+GKT + + ++QYLA +A    G
Sbjct: 165  KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224

Query: 524  NKVFSVE---KWQALYT--LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTM 578
             K   V    + Q L    +LEAFGN+ T+ N N++RF + + ++FD AG +  A+I+T 
Sbjct: 225  RKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETY 284

Query: 579  LLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKA 638
            LLEK R  R+   E +F++FY LL      L+ +L L   +        P + P ++++ 
Sbjct: 285  LLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQEREL 344

Query: 639  AQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKA 698
               F +   +++VLG S +E  +   +++A+   G   A K      +     +  AQK 
Sbjct: 345  ---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMPDNTAAQKL 400

Query: 699  AYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMA 756
              LLG  + + S A+   + K G   +Q++ +  Q                A   LE +A
Sbjct: 401  CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------ADFALEALA 444

Query: 757  AGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASFEELCHNYT 815
               Y  LF  LV  +NRAL  S     S + I+D  GF+  +        SFE+LC NYT
Sbjct: 445  KATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SFEQLCINYT 498

Query: 816  QDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDE 875
             ++LQ+LF+   FV E E Y+ E I   F D        +  +++ ++            
Sbjct: 499  NEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP---------- 548

Query: 876  ARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGT 935
              GLL LL+EE   P A++ + +E++    G   G  K Q P  H      F + H  G 
Sbjct: 549  --GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADFSVLHYAGK 602

Query: 936  NWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGS 995
              V+Y    WL     +P   N   LL  S  ++ + ++    G        I GLE  S
Sbjct: 603  --VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG--------IVGLEQVS 651

Query: 996  QLA--LRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEG 1053
             L          R  F T +  + K+SL          L+ T+  +   FV C +P  E 
Sbjct: 652  SLGDGPPGGRPRRGMFRT-VGQLYKESL--------SRLMATLSNTNPSFVRCIVPNHEK 702

Query: 1054 WAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYP 1113
             AG+                             L+  L+  QLR + +L+ +R+ RQG+P
Sbjct: 703  RAGK-----------------------------LEPRLVLDQLRCNGVLEGIRICRQGFP 733

Query: 1114 DHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFR 1173
            + ++F EFR+R+++L P+   K       +D ++A E++++ L+L+ +   +G S++FFR
Sbjct: 734  NRILFQEFRQRYEILTPNAIPKG-----FMDGKQACEKMIQALELDPNLYRVGQSKIFFR 788

Query: 1174 AGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKD 1233
            AG LA+LEE+RD + +  +  FQAA RGYLAR+ F+KR+ Q  A+R +Q+N      ++ 
Sbjct: 789  AGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRH 848

Query: 1234 WPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQ----------------------------- 1264
            W WW+LFT V+PL++V   +E ++ + +E+Q                             
Sbjct: 849  WQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERAR 908

Query: 1265 ---QLRSKLE---KAEKERNELRLNSDRLESRISELTSELTDERNTGESAS--------- 1309
               QLR++ E   +AE+ R  L      LE  +SEL + + +E                 
Sbjct: 909  LAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQH 968

Query: 1310 -QLLDA--ETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLI--------RAAEI 1358
             Q L+A  E  E  R + +++++ T+    K + +++ +E   ++L         R AE 
Sbjct: 969  IQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEF 1028

Query: 1359 NGEVDDDD----AGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDL 1414
            + +  +++    +  + RLKYE  + +++    RL++E + + E+E+  KR+L+    +L
Sbjct: 1029 SSQAAEEEEKVKSLNKLRLKYEATIADME---DRLRKEEKGRQELEKL-KRRLDGESSEL 1084

Query: 1415 QADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA 1474
            Q    E Q+  ++L+ +  R   ELQ      E +     +L K  R   + L++A E+ 
Sbjct: 1085 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1144

Query: 1475 QREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL--------------- 1519
            + E++ R K ++++  L  E  +L+ +LE+  +D     Q++ S                
Sbjct: 1145 ESERVARTKAEKQRRDLGEELEALRGELED-TLDSTNAQQELRSKREQEVTELKKTLEEE 1203

Query: 1520 ----EAELQDISSQESKDEASLAKVKKQLR-----------DLEAKVKDQEEELDEQAGT 1564
                EA +Q++  +  +    LA+  +Q R            LEA+V +   EL      
Sbjct: 1204 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1263

Query: 1565 IQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEE----YE 1620
             Q  EQ + RLE++++        E++ R  + E AR    +KL++ + +LE       E
Sbjct: 1264 RQEGEQRRRRLELQLQ--------EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1315

Query: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680
             + K +R  +EL    A L D       E+  +L     R +A+ A+A  + + L+  A 
Sbjct: 1316 AESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALG-SRVRAMEAEAAGLREQLEEEAA 1374

Query: 1681 SKR-----------EIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTA 1729
            ++            ++++ + + EE      A  +AR+    E E L  ++ +  +    
Sbjct: 1375 ARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDR 1434

Query: 1730 LEEQLSRLQRE----------KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL------ 1773
            LE    RLQ+E          + ++ + LE+ Q   ++L+ + KAAV +A  +       
Sbjct: 1435 LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAE 1494

Query: 1774 -----AQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM--VDKSL--------VS 1818
                 A+   L   LEE  + ++EL+ + +AL++++E L  S   V KS+        V+
Sbjct: 1495 GREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVA 1554

Query: 1819 RQ-----EAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQN 1873
             Q      A++ ELE  L        RLE     LK   E+  + RD+        +E+ 
Sbjct: 1555 EQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDE------AGEERR 1608

Query: 1874 KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933
            ++L +QLRD + E  E  ++   A   + +LE +LE L+A   S     + A K++  +Q
Sbjct: 1609 RQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQ 1668

Query: 1934 AAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKS 1970
            A ++ E+  +  E   + E     + E E R+ G+++
Sbjct: 1669 AQMK-ELWREVEETRTSREEIFSQNRESEKRLKGLEA 1704



 Score =  192 bits (489), Expect = 2e-48
 Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%)

Query: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301
            R  +E+QL E Q R  D E  +  +  KL++A+ E   +    +  ES+   L+ EL+  
Sbjct: 1271 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1330

Query: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
                  A +LL  ET  +L     ++ ++ +   L++Q+E                    
Sbjct: 1331 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1370

Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420
               ++A    R   E    +   ++ R +QE E   LE  ++ +R+  R    L     E
Sbjct: 1371 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1427

Query: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
                + +L++  +RL  EL D  + LE Q+     LEKKQR+FD  L++      R   +
Sbjct: 1428 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1487

Query: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540
            RE+ + E     A A SL + LEE+        ++  +L AEL+ + S +     S+ ++
Sbjct: 1488 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1547

Query: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
            ++  R  E    D   ++ E    +   E AKLRLE+ ++ ++  H ++++ RDE  EE 
Sbjct: 1548 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1607

Query: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657
            R+   K+L+  EV+ +EE + +   +  +++LEG+L  L  Q+    +   E+ K+LRK 
Sbjct: 1608 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1667

Query: 1658 LKRTKALLADAQLML----DHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713
              + K L  + +       +    +  S++ +  L+ ++   +   AA+ +AR+  + + 
Sbjct: 1668 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1727

Query: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
            +++  ++ +   +K A+ E+  +L+    +++  LEE+Q +   L  +++  + Q     
Sbjct: 1728 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1787

Query: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831
             +++  ++   +A   +Q+L+ ++Q L+ ++  E        K  ++  E+K+ + E +L
Sbjct: 1788 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1847

Query: 1832 EFERTQV----KRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882
            E E  +     K +     RLKE + ++ EER  R+A + R++ +      K+L+RQL +
Sbjct: 1848 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1905

Query: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
             +E   E +R +A   R + ELE   ES E+ N+ +
Sbjct: 1906 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1938



 Score =  156 bits (394), Expect = 2e-37
 Identities = 158/747 (21%), Positives = 329/747 (44%), Gaps = 116/747 (15%)

Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
            +EQ+  + +  ++LR++L + E+E       ++      ++L   L + +     A + L
Sbjct: 1085 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1144

Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
            ++E   R +AEK+ ++L  + +AL+ ++E                    +D  +A  E R
Sbjct: 1145 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1186

Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
             K E+ V E+   KK L++E        Q+ +++  + LG+L    E+++R     +K  
Sbjct: 1187 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243

Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482
              L AE+ + +  L   Q    E E+++RR + +L +    A           EKLQR  
Sbjct: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303

Query: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
                              +L +E     A+    ++ L+E+         +V ++EAE  
Sbjct: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363

Query: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584
             +  Q  ++ A+  +  ++L+  +A++ +     +E+AG ++  E+A+ R   E E + Q
Sbjct: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1423

Query: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626
              +++ E+ D  +E  R+  Q++L    + LE++                   E+K  VL
Sbjct: 1424 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1482

Query: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680
            R     E+ E EG+          R  E E+  R++L+R  +AL A+ + +L        
Sbjct: 1483 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1535

Query: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
            SK ++ +  ++LE          +A +  E    DL  Q+ ++    TA E+   RL+  
Sbjct: 1536 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1585

Query: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
               ++ + E D +  +E  ++ +  +A+      Q+ D + + +E  K++       + L
Sbjct: 1586 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1639

Query: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
            + ++E L+  M       ++EA               VK+L  + +++KE   ++ E R 
Sbjct: 1640 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1683

Query: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
             R  I ++NRE E+  K L+ ++   +EE+    R   +A + + E+  ++ +   +  +
Sbjct: 1684 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1743

Query: 1918 LQADLKLAFKRIGDLQAAIEDEMESDE 1944
            +  + +    R+G L+  +E+E  + E
Sbjct: 1744 ILEEKRQLEGRLGQLEEELEEEQSNSE 1770



 Score =  116 bits (291), Expect = 2e-25
 Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%)

Query: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308
            V   E++ R  D+ + + ++ + +A +ER          E+R   LT  L +E+   E  
Sbjct: 1460 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1519

Query: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
             +   A  AE         ++      L++   V E    + R    A++    D+  A 
Sbjct: 1520 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1575

Query: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426
             + +L+ E  V+ +   K + +++ + + E  ++ +RQL ++L D  ++ D E  QR L 
Sbjct: 1576 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1632

Query: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484
               +K  +L  EL++ K  +        E  K+ R+  +++ +   E +  +  RE++  
Sbjct: 1633 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1690

Query: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
              RE +  L    AE   L+++L   D       +     + +  +++ + +    S A 
Sbjct: 1691 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1743

Query: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
            + ++ R LE ++   EEEL+E+    ++L     +L +++E +    S E  S   + E 
Sbjct: 1744 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1802

Query: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653
             RQ  +++++++  +L EE  D     R K     LE KLA   +Q+ +   E   S K 
Sbjct: 1803 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1860

Query: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709
            +R+  KR K ++   +    + D L++        + QLK QLEE+E   + A   R+ +
Sbjct: 1861 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1920

Query: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736
            + E+ED+    + + +  T L  +L R
Sbjct: 1921 QRELEDVTESAESMNREVTTLRNRLRR 1947


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score =  528 bits (1361), Expect = e-149
 Identities = 478/1785 (26%), Positives = 827/1785 (46%), Gaps = 282/1785 (15%)

Query: 346  WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404
            W     VW+     GF  A+ L+ E     E +  V+L   G  L +  D +++ N P  
Sbjct: 50   WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104

Query: 405  DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464
             + ED+A L  LNE+SVLH LR+RY + L++TY+G   +V+ P     +Y+E ++ M++G
Sbjct: 105  SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164

Query: 465  CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523
             +R ++ PH+YAV + AYR+ML  R+DQSI+  G SG+GKT + + ++QYLA +A    G
Sbjct: 165  KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224

Query: 524  NKVFSVEKWQALYT-------------LLEAFGNSPTIINGNATRFSQILSLDFDQAGQV 570
             K   V    +  +             +LEAFGN+ T+ N N++RF + + ++FD AG +
Sbjct: 225  RKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYI 284

Query: 571  ASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA 630
              A+I+T LLEK R  R+   E +F++FY LL      L+ +L L   +        P +
Sbjct: 285  VGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS 344

Query: 631  KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
             P ++++    F +   +++VLG S +E  +   +++A+   G   A K      +    
Sbjct: 345  SPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMP 400

Query: 691  RHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSA 748
             +  AQK   LLG  + + S A+   + K G   +Q++ +  Q                A
Sbjct: 401  DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------A 444

Query: 749  LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
               LE +A   Y  LF  LV  +NRAL  S     S + I+D  GF+  +        SF
Sbjct: 445  DFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SF 498

Query: 808  EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
            E+LC NYT ++LQ+LF+   FV E E Y+ E I   F D        +  +++ ++    
Sbjct: 499  EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP-- 556

Query: 868  RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
                      GLL LL+EE   P A++ + +E++    G   G  K Q P  H      F
Sbjct: 557  ----------GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADF 602

Query: 928  LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGS 987
             + H  G   V+Y    WL     +P   N   LL  S  ++ + ++    G        
Sbjct: 603  SVLHYAGK--VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG-------- 651

Query: 988  IAGLEGGSQLA--LRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVH 1045
            I GLE  S L          R  F T +  + K+SL          L+ T+  +   FV 
Sbjct: 652  IVGLEQVSSLGDGPPGGRPRRGMFRT-VGQLYKESL--------SRLMATLSNTNPSFVR 702

Query: 1046 CFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAM 1105
            C +P  E  AG+                             L+  L+  QLR + +L+ +
Sbjct: 703  CIVPNHEKRAGK-----------------------------LEPRLVLDQLRCNGVLEGI 733

Query: 1106 RMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCM 1165
            R+ RQG+P+ ++F EFR+R+++L P+   K       +D ++A E++++ L+L+ +   +
Sbjct: 734  RICRQGFPNRILFQEFRQRYEILTPNAIPKG-----FMDGKQACEKMIQALELDPNLYRV 788

Query: 1166 GLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNI 1225
            G S++FFRAG LA+LEE+RD + +  +  FQAA RGYLAR+ F+KR+ Q  A+R +Q+N 
Sbjct: 789  GQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNC 848

Query: 1226 KKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQ--------------------- 1264
                 ++ W WW+LFT V+PL++V   +E ++ + +E+Q                     
Sbjct: 849  AAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVA 908

Query: 1265 -----------QLRSKLE---KAEKERNELRLNSDRLESRISELTSELTDERNTGESAS- 1309
                       QLR++ E   +AE+ R  L      LE  +SEL + + +E         
Sbjct: 909  QLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQT 968

Query: 1310 ---------QLLDA--ETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLI----- 1353
                     Q L+A  E  E  R + +++++ T+    K + +++ +E   ++L      
Sbjct: 969  EKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKL 1028

Query: 1354 ---RAAEINGEVDDDD----AGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQ 1406
               R AE + +  +++    +  + RLKYE  + +++    RL++E + + E+E+  KR+
Sbjct: 1029 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADME---DRLRKEEKGRQELEKL-KRR 1084

Query: 1407 LERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSE 1466
            L+    +LQ    E Q+  ++L+ +  R   ELQ      E +     +L K  R   + 
Sbjct: 1085 LDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAA 1144

Query: 1467 LSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL------- 1519
            L++A E+ + E++ R K ++++  L  E  +L+ +LE+  +D     Q++ S        
Sbjct: 1145 LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED-TLDSTNAQQELRSKREQEVTE 1203

Query: 1520 ------------EAELQDISSQESKDEASLAKVKKQLR-----------DLEAKVKDQEE 1556
                        EA +Q++  +  +    LA+  +Q R            LEA+V +   
Sbjct: 1204 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1263

Query: 1557 ELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLE 1616
            EL       Q  EQ + RLE++++        E++ R  + E AR    +KL++ + +LE
Sbjct: 1264 ELSSLQTARQEGEQRRRRLELQLQ--------EVQGRAGDGERARAEAAEKLQRAQAELE 1315

Query: 1617 EE----YEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML 1672
                   E + K +R  +EL    A L D       E+  +L     R +A+ A+A  + 
Sbjct: 1316 NVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALG-SRVRAMEAEAAGLR 1374

Query: 1673 DHLKNSAPSKR-----------EIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQID 1721
            + L+  A ++            ++++ + + EE      A  +AR+    E E L  ++ 
Sbjct: 1375 EQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLA 1434

Query: 1722 DIAKAKTALEEQLSRLQRE----------KNEIQNRLEEDQEDMNELMKKHKAAVAQASR 1771
            +  +    LE    RLQ+E          + ++ + LE+ Q   ++L+ + KAAV +A  
Sbjct: 1435 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1494

Query: 1772 DL-----------AQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM--VDKSL-- 1816
            +            A+   L   LEE  + ++EL+ + +AL++++E L  S   V KS+  
Sbjct: 1495 ERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHE 1554

Query: 1817 ------VSRQ-----EAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAA 1865
                  V+ Q      A++ ELE  L        RLE     LK   E+  + RD+    
Sbjct: 1555 LERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDE---- 1610

Query: 1866 ENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLA 1925
                +E+ ++L +QLRD + E  E  ++   A   + +LE +LE L+A   S     + A
Sbjct: 1611 --AGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEA 1668

Query: 1926 FKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKS 1970
             K++  +QA ++ E+  +  E   + E     + E E R+ G+++
Sbjct: 1669 VKQLRKMQAQMK-ELWREVEETRTSREEIFSQNRESEKRLKGLEA 1712



 Score =  192 bits (489), Expect = 2e-48
 Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%)

Query: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301
            R  +E+QL E Q R  D E  +  +  KL++A+ E   +    +  ES+   L+ EL+  
Sbjct: 1279 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1338

Query: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
                  A +LL  ET  +L     ++ ++ +   L++Q+E                    
Sbjct: 1339 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1378

Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420
               ++A    R   E    +   ++ R +QE E   LE  ++ +R+  R    L     E
Sbjct: 1379 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1435

Query: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
                + +L++  +RL  EL D  + LE Q+     LEKKQR+FD  L++      R   +
Sbjct: 1436 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1495

Query: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540
            RE+ + E     A A SL + LEE+        ++  +L AEL+ + S +     S+ ++
Sbjct: 1496 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1555

Query: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
            ++  R  E    D   ++ E    +   E AKLRLE+ ++ ++  H ++++ RDE  EE 
Sbjct: 1556 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1615

Query: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657
            R+   K+L+  EV+ +EE + +   +  +++LEG+L  L  Q+    +   E+ K+LRK 
Sbjct: 1616 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1675

Query: 1658 LKRTKALLADAQLML----DHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713
              + K L  + +       +    +  S++ +  L+ ++   +   AA+ +AR+  + + 
Sbjct: 1676 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1735

Query: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
            +++  ++ +   +K A+ E+  +L+    +++  LEE+Q +   L  +++  + Q     
Sbjct: 1736 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1795

Query: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831
             +++  ++   +A   +Q+L+ ++Q L+ ++  E        K  ++  E+K+ + E +L
Sbjct: 1796 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1855

Query: 1832 EFERTQV----KRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882
            E E  +     K +     RLKE + ++ EER  R+A + R++ +      K+L+RQL +
Sbjct: 1856 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1913

Query: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
             +E   E +R +A   R + ELE   ES E+ N+ +
Sbjct: 1914 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1946



 Score =  156 bits (394), Expect = 2e-37
 Identities = 158/747 (21%), Positives = 329/747 (44%), Gaps = 116/747 (15%)

Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
            +EQ+  + +  ++LR++L + E+E       ++      ++L   L + +     A + L
Sbjct: 1093 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1152

Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
            ++E   R +AEK+ ++L  + +AL+ ++E                    +D  +A  E R
Sbjct: 1153 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1194

Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
             K E+ V E+   KK L++E        Q+ +++  + LG+L    E+++R     +K  
Sbjct: 1195 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1251

Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482
              L AE+ + +  L   Q    E E+++RR + +L +    A           EKLQR  
Sbjct: 1252 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1311

Query: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
                              +L +E     A+    ++ L+E+         +V ++EAE  
Sbjct: 1312 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1371

Query: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584
             +  Q  ++ A+  +  ++L+  +A++ +     +E+AG ++  E+A+ R   E E + Q
Sbjct: 1372 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1431

Query: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626
              +++ E+ D  +E  R+  Q++L    + LE++                   E+K  VL
Sbjct: 1432 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1490

Query: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680
            R     E+ E EG+          R  E E+  R++L+R  +AL A+ + +L        
Sbjct: 1491 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1543

Query: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
            SK ++ +  ++LE          +A +  E    DL  Q+ ++    TA E+   RL+  
Sbjct: 1544 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1593

Query: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
               ++ + E D +  +E  ++ +  +A+      Q+ D + + +E  K++       + L
Sbjct: 1594 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1647

Query: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
            + ++E L+  M       ++EA               VK+L  + +++KE   ++ E R 
Sbjct: 1648 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1691

Query: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
             R  I ++NRE E+  K L+ ++   +EE+    R   +A + + E+  ++ +   +  +
Sbjct: 1692 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1751

Query: 1918 LQADLKLAFKRIGDLQAAIEDEMESDE 1944
            +  + +    R+G L+  +E+E  + E
Sbjct: 1752 ILEEKRQLEGRLGQLEEELEEEQSNSE 1778



 Score =  116 bits (291), Expect = 2e-25
 Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%)

Query: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308
            V   E++ R  D+ + + ++ + +A +ER          E+R   LT  L +E+   E  
Sbjct: 1468 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1527

Query: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
             +   A  AE         ++      L++   V E    + R    A++    D+  A 
Sbjct: 1528 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1583

Query: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426
             + +L+ E  V+ +   K + +++ + + E  ++ +RQL ++L D  ++ D E  QR L 
Sbjct: 1584 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1640

Query: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484
               +K  +L  EL++ K  +        E  K+ R+  +++ +   E +  +  RE++  
Sbjct: 1641 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1698

Query: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
              RE +  L    AE   L+++L   D       +     + +  +++ + +    S A 
Sbjct: 1699 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1751

Query: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
            + ++ R LE ++   EEEL+E+    ++L     +L +++E +    S E  S   + E 
Sbjct: 1752 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1810

Query: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653
             RQ  +++++++  +L EE  D     R K     LE KLA   +Q+ +   E   S K 
Sbjct: 1811 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1868

Query: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709
            +R+  KR K ++   +    + D L++        + QLK QLEE+E   + A   R+ +
Sbjct: 1869 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1928

Query: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736
            + E+ED+    + + +  T L  +L R
Sbjct: 1929 QRELEDVTESAESMNREVTTLRNRLRR 1955


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score =  527 bits (1357), Expect = e-149
 Identities = 482/1811 (26%), Positives = 838/1811 (46%), Gaps = 301/1811 (16%)

Query: 346  WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404
            W     VW+     GF  A+ L+ E     E +  V+L   G  L +  D +++ N P  
Sbjct: 50   WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104

Query: 405  DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464
             + ED+A L  LNE+SVLH LR+RY + L++TY+G   +V+ P     +Y+E ++ M++G
Sbjct: 105  SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164

Query: 465  CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523
             +R ++ PH+YAV + AYR+ML  R+DQSI+  G SG+GKT + + ++QYLA +A    G
Sbjct: 165  KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224

Query: 524  NKVFSVEKWQALYT-------------LLEAFGNSPTIINGNATRFSQILSLDFDQAGQV 570
             K   V    +  +             +LEAFGN+ T+ N N++RF + + ++FD AG +
Sbjct: 225  RKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYI 284

Query: 571  ASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA 630
              A+I+T LLEK R  R+   E +F++FY LL      L+ +L L   +        P +
Sbjct: 285  VGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS 344

Query: 631  KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
             P ++++    F +   +++VLG S +E  +   +++A+   G   A K      +    
Sbjct: 345  SPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMP 400

Query: 691  RHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSA 748
             +  AQK   LLG  + + S A+   + K G   +Q++ +  Q                A
Sbjct: 401  DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------A 444

Query: 749  LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
               LE +A   Y  LF  LV  +NRAL  S     S + I+D  GF+  +        SF
Sbjct: 445  DFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SF 498

Query: 808  EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
            E+LC NYT ++LQ+LF+   FV E E Y+ E I   F D        +  +++ ++    
Sbjct: 499  EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP-- 556

Query: 868  RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
                      GLL LL+EE   P A++ + +E++    G   G  K Q P  H      F
Sbjct: 557  ----------GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADF 602

Query: 928  LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNL------------FL 975
             + H  G   V+Y    WL     +P   N   LL  S  ++ + +            FL
Sbjct: 603  SVLHYAGK--VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFL 659

Query: 976  GR-----AGSATVLSGSIA--GLEGGSQLALRRATSM---------RKTFTTGMAAVKKK 1019
            G       GSA   S +I+  G+EG   + L + +S+         R+     +  + K+
Sbjct: 660  GSFPPSPPGSAERCSSAISPPGVEG--IVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKE 717

Query: 1020 SLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDH 1079
            SL          L+ T+  +   FV C +P  E  AG+                      
Sbjct: 718  SL--------SRLMATLSNTNPSFVRCIVPNHEKRAGK---------------------- 747

Query: 1080 CEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRN 1139
                   L+  L+  QLR + +L+ +R+ RQG+P+ ++F EFR+R+++L P+   K    
Sbjct: 748  -------LEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG--- 797

Query: 1140 YIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAAC 1199
               +D ++A E++++ L+L+ +   +G S++FFRAG LA+LEE+RD + +  +  FQAA 
Sbjct: 798  --FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 855

Query: 1200 RGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNK 1259
            RGYLAR+ F+KR+ Q  A+R +Q+N      ++ W WW+LFT V+PL++V   +E ++ +
Sbjct: 856  RGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQAR 915

Query: 1260 DEEIQ--------------------------------QLRSKLE---KAEKERNELRLNS 1284
             +E+Q                                QLR++ E   +AE+ R  L    
Sbjct: 916  AQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARK 975

Query: 1285 DRLESRISELTSELTDERNTGESAS----------QLLDA--ETAERLRAEKEMKELQTQ 1332
              LE  +SEL + + +E                  Q L+A  E  E  R + +++++ T+
Sbjct: 976  QELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTE 1035

Query: 1333 YDALKKQMEVMEMEVMEARLI--------RAAEINGEVDDDD----AGGEWRLKYERAVR 1380
                K + +++ +E   ++L         R AE + +  +++    +  + RLKYE  + 
Sbjct: 1036 AKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIA 1095

Query: 1381 EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1440
            +++    RL++E + + E+E+  KR+L+    +LQ    E Q+  ++L+ +  R   ELQ
Sbjct: 1096 DME---DRLRKEEKGRQELEKL-KRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ 1151

Query: 1441 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1500
                  E +     +L K  R   + L++A E+ + E++ R K ++++  L  E  +L+ 
Sbjct: 1152 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG 1211

Query: 1501 QLEEKDMDIAGFTQKVVSL-------------------EAELQDISSQESKDEASLAKVK 1541
            +LE+  +D     Q++ S                    EA +Q++  +  +    LA+  
Sbjct: 1212 ELED-TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQL 1270

Query: 1542 KQLR-----------DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEM 1590
            +Q R            LEA+V +   EL       Q  EQ + RLE++++        E+
Sbjct: 1271 EQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ--------EV 1322

Query: 1591 ESRDEEVEEARQSCQKKLKQMEVQLEEE----YEDKQKVLREKRELEGKLATLSDQVNRR 1646
            + R  + E AR    +KL++ + +LE       E + K +R  +EL    A L D     
Sbjct: 1323 QGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELL 1382

Query: 1647 DFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKR-----------EIAQLKNQLEES 1695
              E+  +L     R +A+ A+A  + + L+  A ++            ++++ + + EE 
Sbjct: 1383 QEETRAKLALG-SRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE 1441

Query: 1696 EFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE----------KNEIQ 1745
                 A  +AR+    E E L  ++ +  +    LE    RLQ+E          + ++ 
Sbjct: 1442 AGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLV 1501

Query: 1746 NRLEEDQEDMNELMKKHKAAVAQASRDL-----------AQINDLQAQLEEANKEKQELQ 1794
            + LE+ Q   ++L+ + KAAV +A  +            A+   L   LEE  + ++EL+
Sbjct: 1502 STLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELE 1561

Query: 1795 EKLQALQSQVEFLEQSM--VDKSL--------VSRQ-----EAKIRELETRLEFERTQVK 1839
             + +AL++++E L  S   V KS+        V+ Q      A++ ELE  L        
Sbjct: 1562 RQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKL 1621

Query: 1840 RLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASR 1899
            RLE     LK   E+  + RD+        +E+ ++L +QLRD + E  E  ++   A  
Sbjct: 1622 RLEVTVQALKTQHERDLQGRDE------AGEERRRQLAKQLRDAEVERDEERKQRTLAVA 1675

Query: 1900 KKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDS 1959
             + +LE +LE L+A   S     + A K++  +QA ++ E+  +  E   + E     + 
Sbjct: 1676 ARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK-ELWREVEETRTSREEIFSQNR 1734

Query: 1960 ELEDRVDGVKS 1970
            E E R+ G+++
Sbjct: 1735 ESEKRLKGLEA 1745



 Score =  192 bits (489), Expect = 2e-48
 Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%)

Query: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301
            R  +E+QL E Q R  D E  +  +  KL++A+ E   +    +  ES+   L+ EL+  
Sbjct: 1312 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371

Query: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
                  A +LL  ET  +L     ++ ++ +   L++Q+E                    
Sbjct: 1372 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1411

Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420
               ++A    R   E    +   ++ R +QE E   LE  ++ +R+  R    L     E
Sbjct: 1412 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1468

Query: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
                + +L++  +RL  EL D  + LE Q+     LEKKQR+FD  L++      R   +
Sbjct: 1469 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1528

Query: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540
            RE+ + E     A A SL + LEE+        ++  +L AEL+ + S +     S+ ++
Sbjct: 1529 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1588

Query: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
            ++  R  E    D   ++ E    +   E AKLRLE+ ++ ++  H ++++ RDE  EE 
Sbjct: 1589 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1648

Query: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657
            R+   K+L+  EV+ +EE + +   +  +++LEG+L  L  Q+    +   E+ K+LRK 
Sbjct: 1649 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1708

Query: 1658 LKRTKALLADAQLML----DHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713
              + K L  + +       +    +  S++ +  L+ ++   +   AA+ +AR+  + + 
Sbjct: 1709 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1768

Query: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
            +++  ++ +   +K A+ E+  +L+    +++  LEE+Q +   L  +++  + Q     
Sbjct: 1769 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1828

Query: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831
             +++  ++   +A   +Q+L+ ++Q L+ ++  E        K  ++  E+K+ + E +L
Sbjct: 1829 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1888

Query: 1832 EFERTQV----KRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882
            E E  +     K +     RLKE + ++ EER  R+A + R++ +      K+L+RQL +
Sbjct: 1889 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1946

Query: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
             +E   E +R +A   R + ELE   ES E+ N+ +
Sbjct: 1947 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1979



 Score =  156 bits (394), Expect = 2e-37
 Identities = 158/747 (21%), Positives = 329/747 (44%), Gaps = 116/747 (15%)

Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
            +EQ+  + +  ++LR++L + E+E       ++      ++L   L + +     A + L
Sbjct: 1126 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1185

Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
            ++E   R +AEK+ ++L  + +AL+ ++E                    +D  +A  E R
Sbjct: 1186 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1227

Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
             K E+ V E+   KK L++E        Q+ +++  + LG+L    E+++R     +K  
Sbjct: 1228 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1284

Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482
              L AE+ + +  L   Q    E E+++RR + +L +    A           EKLQR  
Sbjct: 1285 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1344

Query: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
                              +L +E     A+    ++ L+E+         +V ++EAE  
Sbjct: 1345 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1404

Query: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584
             +  Q  ++ A+  +  ++L+  +A++ +     +E+AG ++  E+A+ R   E E + Q
Sbjct: 1405 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1464

Query: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626
              +++ E+ D  +E  R+  Q++L    + LE++                   E+K  VL
Sbjct: 1465 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1523

Query: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680
            R     E+ E EG+          R  E E+  R++L+R  +AL A+ + +L        
Sbjct: 1524 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1576

Query: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
            SK ++ +  ++LE          +A +  E    DL  Q+ ++    TA E+   RL+  
Sbjct: 1577 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1626

Query: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
               ++ + E D +  +E  ++ +  +A+      Q+ D + + +E  K++       + L
Sbjct: 1627 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1680

Query: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
            + ++E L+  M       ++EA               VK+L  + +++KE   ++ E R 
Sbjct: 1681 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1724

Query: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
             R  I ++NRE E+  K L+ ++   +EE+    R   +A + + E+  ++ +   +  +
Sbjct: 1725 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1784

Query: 1918 LQADLKLAFKRIGDLQAAIEDEMESDE 1944
            +  + +    R+G L+  +E+E  + E
Sbjct: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSE 1811



 Score =  116 bits (291), Expect = 2e-25
 Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%)

Query: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308
            V   E++ R  D+ + + ++ + +A +ER          E+R   LT  L +E+   E  
Sbjct: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560

Query: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
             +   A  AE         ++      L++   V E    + R    A++    D+  A 
Sbjct: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1616

Query: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426
             + +L+ E  V+ +   K + +++ + + E  ++ +RQL ++L D  ++ D E  QR L 
Sbjct: 1617 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1673

Query: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484
               +K  +L  EL++ K  +        E  K+ R+  +++ +   E +  +  RE++  
Sbjct: 1674 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1731

Query: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
              RE +  L    AE   L+++L   D       +     + +  +++ + +    S A 
Sbjct: 1732 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1784

Query: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
            + ++ R LE ++   EEEL+E+    ++L     +L +++E +    S E  S   + E 
Sbjct: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1843

Query: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653
             RQ  +++++++  +L EE  D     R K     LE KLA   +Q+ +   E   S K 
Sbjct: 1844 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1901

Query: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709
            +R+  KR K ++   +    + D L++        + QLK QLEE+E   + A   R+ +
Sbjct: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961

Query: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736
            + E+ED+    + + +  T L  +L R
Sbjct: 1962 QRELEDVTESAESMNREVTTLRNRLRR 1988


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score =  515 bits (1326), Expect = e-145
 Identities = 420/1668 (25%), Positives = 796/1668 (47%), Gaps = 219/1668 (13%)

Query: 366  LKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTL 425
            +K++ ++   GKV  + ++ G  + V ED V + N P  D++ED+A L +L+E +VL+ L
Sbjct: 47   VKAKIVSREGGKVTAETEY-GKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNL 105

Query: 426  RQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAM 485
            + RYG+ +++TY+G   + + P     VY+ +V+  ++G +R +  PHI++++  AY+ M
Sbjct: 106  KDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYM 165

Query: 486  LMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI--------SGNKVFSVEKWQALYT 537
            L  R++QSI++ G SG+GKT + + ++QY A IA I        S  K    ++      
Sbjct: 166  LTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANP 225

Query: 538  LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNV 597
             LEAFGN+ T+ N N++RF + + + F   G++ASA I+T LLEK RV  +  +E  +++
Sbjct: 226  ALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHI 285

Query: 598  FYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGI 654
            FY +L+      + EL    L  NN +    +++ E    +     +L A   A  VLG 
Sbjct: 286  FYQILS----NKKPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGF 341

Query: 655  SPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIF 714
            + +E+ + + +  AI H G      +  E   +     E A K+AYL+G +  +L   + 
Sbjct: 342  TSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEE-ADKSAYLMGLNSADLLKGLC 400

Query: 715  KHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRA 774
              + K G    +    +G     +   TG           +A  +Y  +F  +V+ +N  
Sbjct: 401  HPRVKVG----NEYVTKGQNVQQVIYATG----------ALAKAVYERMFNWMVTRINAT 446

Query: 775  LKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELER 834
            L++ Q     + ++D  GF+  +        SFE+LC N+T ++LQ+ F+   FV E E 
Sbjct: 447  LETKQPRQYFIGVLDIAGFEIFDFN------SFEQLCINFTNEKLQQFFNHHMFVLEQEE 500

Query: 835  YKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASE 894
            YK+E IE  F D      D  A +D              ++  G++ +LEEE + P A++
Sbjct: 501  YKKEGIEWTFIDFGM---DLQACID------------LIEKPMGIMSILEEECMFPKATD 545

Query: 895  DTLLERLFSYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNP 953
             T   +LF  +  +  +   Q P     KP  HF L H  G   V+YN+ GWL   K +P
Sbjct: 546  MTFKAKLFDNHLGKSAN--FQKPRNIKGKPEAHFSLIHYAGI--VDYNIIGWLQKNK-DP 600

Query: 954  ATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGM 1013
              +    L Q S  K++S LF   AG+   +       + GS            +F T +
Sbjct: 601  LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGS------------SFQT-V 647

Query: 1014 AAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELD 1073
            +A+ +++L        + L+  ++ +  HFV C +P       E +S             
Sbjct: 648  SALHRENL--------NKLMTNLRSTHPHFVRCIIP------NETKSPG----------- 682

Query: 1074 LPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLT 1133
                         +D PL+  QLR + +L+ +R+ R+G+P+ +++ +FR+R+ +L P   
Sbjct: 683  ------------VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAI 730

Query: 1134 KKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLT 1193
             +       +D R+  E+LL  LD++ +    G ++VFF+AG L  LEE RDE+ SR +T
Sbjct: 731  PEGQ----FIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIIT 786

Query: 1194 LFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSE 1253
              QA  RG LAR  +KK   +  ++  +Q NI+   GVK+WPW KL+  ++PL++    E
Sbjct: 787  RIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAERE 846

Query: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLD 1313
            +++ +  EE  +L+  LEK+E  R EL      L    ++L  ++  E++    A +  D
Sbjct: 847  KEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCD 906

Query: 1314 AETAERLRAEKEMKELQTQYDALKKQMEV-MEMEVMEARL-IRAAEINGEVDDDDAGGEW 1371
                 +++ E ++KE+    + L+ + E+  E+   + +L    +E+  ++DD       
Sbjct: 907  QLIKNKIQLEAKVKEMN---ERLEDEEEMNAELTAKKRKLEDECSELKRDIDD------L 957

Query: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQ------QNKRQL----ERRLGDLQADSEES 1421
             L   +  +E   T+ +++   E+   +++      + K+ L    ++ L DLQA+ ++ 
Sbjct: 958  ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK- 1016

Query: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREK 1478
               +  L K   +L  ++ D +  LE ++    +LE+ +R+ + +L    E   + + +K
Sbjct: 1017 ---VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK 1073

Query: 1479 LQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538
             Q ++  ++KD    E  +L  ++E++    +   +K+  L+A ++++  +   +  + A
Sbjct: 1074 QQLDERLKKKDF---ELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130

Query: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTIQM------------------LEQAKLRLEMEME 1580
            KV+K   DL  ++++  E L+E  G   +                  LE+A L+ E    
Sbjct: 1131 KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1190

Query: 1581 RMRQTHSKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLA 1637
             +R+ H+  +    E++   +  +Q  +K+  + +++L++   + +++++ K  LE    
Sbjct: 1191 ALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCR 1250

Query: 1638 TLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1697
            TL DQ+N    ++E+  R               + D     A  + E  +L  QL+E E 
Sbjct: 1251 TLEDQMNEHRSKAEETQRS--------------VNDLTSQRAKLQTENGELSRQLDEKEA 1296

Query: 1698 TCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE---D 1754
              +   + +     ++EDL  Q+++  KAK AL   L   + + + ++ + EE+ E   +
Sbjct: 1297 LISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAE 1356

Query: 1755 MNELMKKHKAAVAQ------------------ASRDLAQ-INDLQAQLEEANKEKQELQE 1795
            +  ++ K  + VAQ                  A + LAQ + + +  +E  N +   L++
Sbjct: 1357 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 1416

Query: 1796 KLQALQSQVEFL----EQSMVDKSLVSRQEAK----IRELETRLEFERTQVKRLESLASR 1847
                LQ+++E L    E+S    + + +++      + E + + E  +++++  +  A  
Sbjct: 1417 TKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS 1476

Query: 1848 LKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMG---------ELARKEAEAS 1898
            L   + KL    ++ +      K +NK LQ ++ D  E++G         E  RK+ EA 
Sbjct: 1477 LSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEA- 1535

Query: 1899 RKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENE 1946
             +K EL+  LE  EA+ +  +  +  A      ++A IE ++   + E
Sbjct: 1536 -EKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE 1582



 Score =  193 bits (490), Expect = 2e-48
 Identities = 177/797 (22%), Positives = 373/797 (46%), Gaps = 39/797 (4%)

Query: 1144 DERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYL 1203
            D  R +EE+ E   LE++    G + V          E Q+  +     TL   A    L
Sbjct: 1138 DLSRELEEISE--RLEEAG---GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAAL 1192

Query: 1204 ARQHFKKRKIQDLA-----IRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS-EEQIR 1257
             ++H     + +L      ++ V++ ++K K         + + +  +I+ + + E+  R
Sbjct: 1193 RKKHADS--VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCR 1250

Query: 1258 NKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETA 1317
              ++++ + RSK E+ ++  N+L     +L++   EL+ +L DE+        L+   T 
Sbjct: 1251 TLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQL-DEKEA------LISQLTR 1303

Query: 1318 ERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYER 1377
             +L   +++++L+ Q +   K    +   +  AR           ++ +A  E +    +
Sbjct: 1304 GKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSK 1363

Query: 1378 AVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
            A  EV   + + + +   + E  ++ K++L +RL + +   E        L+K   RL  
Sbjct: 1364 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQN 1423

Query: 1438 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
            E++D  + +E        L+KKQR FD  L++  ++ +  + + E  Q+E   L  E F 
Sbjct: 1424 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1483

Query: 1498 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1557
            LK   EE    +  F ++  +L+ E+ D++ Q      ++ +++K  + LEA+  + +  
Sbjct: 1484 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543

Query: 1558 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
            L+E   +++  E   LR ++E  +++    +++  +DEE+E+A+++  + +  ++  L+ 
Sbjct: 1544 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1603

Query: 1618 EYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKR---LRKDLKRTKALLADAQLM 1671
            E   + + LR K+++EG L  +  Q+   NR   E++K+   L+  LK T+  L DA   
Sbjct: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663

Query: 1672 LDHLK-NSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTAL 1730
             D LK N A  +R    L+ +LEE         ++RK  E E+ +   ++  +    T+L
Sbjct: 1664 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1723

Query: 1731 EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---SRDLAQINDLQAQLEEAN 1787
              Q  ++  + +++Q  +EE  ++     +K K A+  A   + +L +  D  A LE   
Sbjct: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE--- 1780

Query: 1788 KEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERTQ----VKRL 1841
            + K+ +++ ++ LQ +++  EQ  +   K  + + EA++RELE  LE E+ +    VK +
Sbjct: 1781 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGM 1840

Query: 1842 ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
                 R+KE   +  E+R   +  ++   +   +++   R  +E   +     ++  + +
Sbjct: 1841 RKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 1900

Query: 1902 HELEMDLESLEAANQSL 1918
            HEL+   E  + A   +
Sbjct: 1901 HELDEAEERADIAESQV 1917



 Score =  169 bits (428), Expect = 3e-41
 Identities = 196/849 (23%), Positives = 392/849 (46%), Gaps = 87/849 (10%)

Query: 1176 TLARLEEQRD--EQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKD 1233
            TLA++E+++   E   +NLT   A     +A+   +K+ +Q+      Q+ +   +  +D
Sbjct: 960  TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH----QQALDDLQAEED 1015

Query: 1234 WPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKE-RNELRLNSDR---LES 1289
                K+ T  +  ++++   + +    E+ +++R  LE+A+++   +L+L  +    LE+
Sbjct: 1016 ----KVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEN 1071

Query: 1290 RISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
               +L   L  +     + +  ++ E A   + +K++KELQ + + L++++E       +
Sbjct: 1072 DKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK 1131

Query: 1350 ARLIRAAEINGEVDD-----DDAGGEWRLKYE-RAVREVDFTKKRLQQEFEDKLEVEQQN 1403
               +R+ +++ E+++     ++AGG   ++ E    RE +F K R  ++ E+     +  
Sbjct: 1132 VEKLRS-DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMR--RDLEEATLQHEAT 1188

Query: 1404 KRQLERRLGDLQADSEES----QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKK 1459
               L ++  D  A+  E     QR  Q+L+K+      EL D   ++E        LEK 
Sbjct: 1189 AAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKM 1248

Query: 1460 QRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL 1519
             R  + ++++   +A+  +     L  ++  L  E   L +QL+EK+  I+  T+  ++ 
Sbjct: 1249 CRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTY 1308

Query: 1520 EAELQDISSQ---ESKDEASLAKVKKQLR-DLEAKVKDQEEELDEQAGTIQMLEQAKLRL 1575
              +L+D+  Q   E K + +LA   +  R D +   +  EEE + +A   ++L +A    
Sbjct: 1309 TQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKAN--- 1365

Query: 1576 EMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGK 1635
              E+ + R  +  +   R EE+EEA++   ++L++ E  +E        + + K  L+ +
Sbjct: 1366 -SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNE 1424

Query: 1636 LATLSDQVNRRDF------ESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS-KREIAQL 1688
            +  L   V R +       + ++   K L   K    ++Q  L+  +  A S   E+ +L
Sbjct: 1425 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKL 1484

Query: 1689 KNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1748
            KN  EES        +  K ++ EI DL  Q+    K    LE+   +L+ EK E+Q+ L
Sbjct: 1485 KNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSAL 1544

Query: 1749 EEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLE 1808
            EE                A+AS +  +   L+AQLE  N+ K E++ KL     ++E  +
Sbjct: 1545 EE----------------AEASLEHEEGKILRAQLE-FNQIKAEIERKLAEKDEEMEQAK 1587

Query: 1809 QSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENR 1868
            ++ +           +  L+T L+ E     R  + A R+K+ ME    E + +++  NR
Sbjct: 1588 RNHL---------RVVDSLQTSLDAET----RSRNEALRVKKKMEGDLNEMEIQLSHANR 1634

Query: 1869 ----EKEQNKRLQRQLRDTKEEMGELARKE-------AEASRKKHELEMDLESLEAANQS 1917
                 ++Q K LQ  L+DT+ ++ +  R         A   R+ + L+ +LE L A  + 
Sbjct: 1635 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1694

Query: 1918 LQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD-SELEDRV-DGVKSWLSKN 1975
             +   KLA + +  ++ +   ++   +N  LIN +   D D S+L+  V + V+   +  
Sbjct: 1695 TERSRKLAEQEL--IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752

Query: 1976 KGPSKAASD 1984
            +   KA +D
Sbjct: 1753 EKAKKAITD 1761



 Score =  118 bits (296), Expect = 5e-26
 Identities = 131/594 (22%), Positives = 267/594 (44%), Gaps = 68/594 (11%)

Query: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307
            +  L  EQ   + E   +L+  L KA  E  + R    + E+   + T EL + +   + 
Sbjct: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT---KYETDAIQRTEELEEAKK--KL 1393

Query: 1308 ASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDA 1367
            A +L +AE A       +   L+     L+ ++E + ++V  +    AA    + + D  
Sbjct: 1394 AQRLQEAEEAVEA-VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKI 1452

Query: 1368 GGEWRLKYERAVREVDFTKK----------RLQQEFEDKLEVEQQNKRQ---LERRLGDL 1414
              EW+ KYE +  E++ ++K          +L+  +E+ LE  +  KR+   L+  + DL
Sbjct: 1453 LAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512

Query: 1415 QADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA 1474
                  S + + +L+K  ++L AE  + +  LE  +      E K  R   E +Q   E 
Sbjct: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572

Query: 1475 QREKLQR-EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKD 1533
            +R+  ++ E++++ K   L    SL+  L+ +        +    +E +L ++  Q S  
Sbjct: 1573 ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632

Query: 1534 EASLAKVKKQLRDLEAKVKDQEEELDEQAGT-------IQMLEQAKLRLEMEMERMRQTH 1586
                A+ +KQ++ L++ +KD + +LD+           I ++E+    L+ E+E +R   
Sbjct: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1692

Query: 1587 SKEMESR---DEEVEEARQSCQ----------KKLKQMEVQLEEEYEDKQKVLREKRELE 1633
             +   SR   ++E+ E  +  Q           + K+M+  L +   + ++ ++E R  E
Sbjct: 1693 EQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752

Query: 1634 GKL-------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLMLDHLKNSAPS--- 1681
             K        A +++++ +    S   +R++K++++T   + D Q  LD  +  A     
Sbjct: 1753 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGK 1809

Query: 1682 ------KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1735
                  +  + +L+N+LE  +   A +VK  +  E  I++L  Q ++  K    L++ + 
Sbjct: 1810 KQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1869

Query: 1736 RLQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QINDLQAQ 1782
            +LQ +    + + EE +E  N  + K     H+   A+   D+A  Q+N L+A+
Sbjct: 1870 KLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAK 1923



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 68/319 (21%), Positives = 154/319 (48%), Gaps = 18/319 (5%)

Query: 1247 IEVQLS---------EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSE 1297
            +E+QLS         ++Q+++    ++  + +L+ A +  ++L+ N   +E R + L +E
Sbjct: 1625 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1684

Query: 1298 LTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 1357
            L + R   E   +       E +   + ++ L +Q  +L  Q + M+ ++ + +     E
Sbjct: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ----TE 1740

Query: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417
            +   V +     E   K ++A+ +     + L++E +    +E+  K+ +E+ + DLQ  
Sbjct: 1741 VEEAVQECRNAEE---KAKKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTIKDLQHR 1796

Query: 1418 SEESQR-ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476
             +E+++ AL+  KK+ Q+L A +++ +  LE +Q RN E  K  R+ +  + +   + + 
Sbjct: 1797 LDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEE 1856

Query: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS 1536
            ++    +LQ   D L  +  + K+Q EE +        K   ++ EL +   +    E+ 
Sbjct: 1857 DRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1916

Query: 1537 LAKVKKQLRDLEAKVKDQE 1555
            + K++ + RD+  K  ++E
Sbjct: 1917 VNKLRAKSRDIGTKGLNEE 1935


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score =  513 bits (1322), Expect = e-145
 Identities = 430/1685 (25%), Positives = 810/1685 (48%), Gaps = 224/1685 (13%)

Query: 366  LKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTL 425
            +K++ L+   GKV  + ++ G  + V ED V + N P  D++ED+A L +L+E +VL  L
Sbjct: 47   VKAKILSREGGKVIAETEN-GKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNL 105

Query: 426  RQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAM 485
            ++RY A +++TY+G   + + P     VY+ +V+  ++G +R +  PHI++++  AY+ M
Sbjct: 106  KERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYM 165

Query: 486  LMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI---------SGNKVFSVEKWQALY 536
            L  R++QSI++ G SG+GKT + + ++QY A+IA I         + NK    ++     
Sbjct: 166  LTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQAN 225

Query: 537  TLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFN 596
              LEAFGN+ T+ N N++RF + + + F   G++ASA I+T LLEK RV  +  +E  ++
Sbjct: 226  PALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYH 285

Query: 597  VFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLG 653
            +FY +L+      + EL    L  NN +    +++ E    +     +L A   A  VLG
Sbjct: 286  IFYQILS----NKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLG 341

Query: 654  ISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAI 713
             + +E+   + +  AI H G     ++  E   +     + A K+AYL+G +  +L   +
Sbjct: 342  FTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTED-ADKSAYLMGLNSADLLKGL 400

Query: 714  FKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLV 771
               + K G   + +  S +Q     G                 +A  +Y ++F  +V+ +
Sbjct: 401  CHPRVKVGNEYVTKGQSVQQVYYSIG----------------ALAKAVYEKMFNWMVTRI 444

Query: 772  NRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQE 831
            N  L++ Q     + ++D  GF+  +        SFE+LC N+T ++LQ+ F+   FV E
Sbjct: 445  NATLETKQPRQYFIGVLDIAGFEIFDFN------SFEQLCINFTNEKLQQFFNHHMFVLE 498

Query: 832  LERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPG 891
             E YK+E IE  F D      D  A +D              ++  G++ +LEEE + P 
Sbjct: 499  QEEYKKEGIEWTFIDFGM---DLQACIDLI------------EKPMGIMSILEEECMFPK 543

Query: 892  ASEDTLLERLF-SYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTK 950
            A++ T   +L+ ++ G     +K ++  +   +  HF L H  GT  V+YN+ GWL   K
Sbjct: 544  ATDMTFKAKLYDNHLGKSNNFQKPRN--IKGKQEAHFSLIHYAGT--VDYNILGWLEKNK 599

Query: 951  QNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSG-SIAGLEGGSQLALRRATSMRKTF 1009
             +P  +    L Q S  K+++ LF   A + T  SG S  G + GS            +F
Sbjct: 600  -DPLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGS------------SF 646

Query: 1010 TTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSS 1069
             T ++A+ +++L        + L+  ++ +  HFV C +P                    
Sbjct: 647  QT-VSALHRENL--------NKLMTNLRTTHPHFVRCIIP-------------------- 677

Query: 1070 SELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLA 1129
            +E   P           +D PL+  QLR + +L+ +R+ R+G+P+ +++ +FR+R+ +L 
Sbjct: 678  NERKAPG---------VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILN 728

Query: 1130 PHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTS 1189
            P +    G+    +D R+  E+LL  LD++ +    G ++VFF+AG L  LEE RDE+ S
Sbjct: 729  P-VAIPEGQ---FIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLS 784

Query: 1190 RNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEV 1249
            R +T  QA  RG L R  FKK   +  A+  +Q NI+   GVK+WPW KL+  ++PL++ 
Sbjct: 785  RIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKS 844

Query: 1250 QLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESAS 1309
              +E+++    EE  +++  LEK+E  R EL      L    ++L  ++  E++    A 
Sbjct: 845  AETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAE 904

Query: 1310 QLLDAETAERLRAEKEMKELQTQYDALKKQMEV-MEMEVMEARL-IRAAEINGEVDDDDA 1367
            +  D     +++ E ++KE+    + L+ + E+  E+   + +L    +E+  ++DD   
Sbjct: 905  ERCDQLIKNKIQLEAKVKEMN---ERLEDEEEMNAELTAKKRKLEDECSELKKDIDD--- 958

Query: 1368 GGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ------QNKRQL----ERRLGDLQAD 1417
                 L   +  +E   T+ +++   E+   +++      + K+ L    ++ L DLQ +
Sbjct: 959  ---LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVE 1015

Query: 1418 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQRE 1477
             ++    +  L K   +L  ++ D +  LE ++    +LE+ +R+ + +L    E     
Sbjct: 1016 EDK----VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM-- 1069

Query: 1478 KLQREKLQREKDMLLAEAFSLKQQ---LEEKDMDIAGFTQKVVSLEAELQDISSQESKDE 1534
             L+ +KLQ E + L  + F + QQ   +E++ +      +K+   +A ++++  +   + 
Sbjct: 1070 DLENDKLQLE-EKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAER 1128

Query: 1535 ASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQM------------------LEQAKLRLE 1576
             + AKV+K   DL  ++++  E L+E  G   +                  LE+A L+ E
Sbjct: 1129 TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHE 1188

Query: 1577 MEMERMRQTHSKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633
                 +R+ H+  +    E++   +  +Q  +K+  + +++L++   + +++++ K  LE
Sbjct: 1189 ATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE 1248

Query: 1634 GKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML-DHLKNSAPSKREIAQLKNQL 1692
                TL DQ N      E R++         L +AQ  L D     A  + E  +L  QL
Sbjct: 1249 KVSRTLEDQAN------EYRVK---------LEEAQRSLNDFTTQRAKLQTENGELARQL 1293

Query: 1693 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1752
            EE E   +   + + +   ++EDL  Q+++  KAK AL   L   + + + ++ + EE+ 
Sbjct: 1294 EEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEET 1353

Query: 1753 E---DMNELMKKHKAAVAQ------------------ASRDLAQ-INDLQAQLEEANKEK 1790
            E   ++  ++ K  + VAQ                  A + LAQ + D +  +E  N + 
Sbjct: 1354 EAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKC 1413

Query: 1791 QELQEKLQALQSQVEFL----EQSMVDKSLVSRQEAK----IRELETRLEFERTQVKRLE 1842
              L++    LQ+++E L    E+S    + + +++      + E + + E  +++++  +
Sbjct: 1414 SSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQ 1473

Query: 1843 SLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKH 1902
              A  L   + KL    ++ +      K +NK LQ ++ D  E++GE  +   E  + + 
Sbjct: 1474 KEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRK 1533

Query: 1903 ELEMDLESLEAANQSLQADLK-------LAFKRIGDLQAAIEDEM-ESDENEDLINSEGD 1954
            +LE++   L++A +  +A L+        A      ++A IE ++ E DE  +       
Sbjct: 1534 QLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQ 1593

Query: 1955 SDVDS 1959
              VDS
Sbjct: 1594 RVVDS 1598



 Score =  199 bits (505), Expect = 3e-50
 Identities = 183/818 (22%), Positives = 382/818 (46%), Gaps = 40/818 (4%)

Query: 1144 DERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYL 1203
            D  R +EE+ E   LE++    G + V          E Q+  +     TL   A    L
Sbjct: 1140 DLSRELEEISE--RLEEAG---GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAAL 1194

Query: 1204 ARQHFKKRKIQDLA-----IRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQI-R 1257
             ++H     + +L      ++ V++ ++K K         + + +  +I+ + + E++ R
Sbjct: 1195 RKKHADS--VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSR 1252

Query: 1258 NKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETA 1317
              +++  + R KLE+A++  N+      +L++   EL  +L       E    L+   T 
Sbjct: 1253 TLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQL-------EEKEALISQLTR 1305

Query: 1318 ERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYER 1377
             +L   ++M++L+ Q +   K    +   +  AR           ++ +A  E +    +
Sbjct: 1306 GKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSK 1365

Query: 1378 AVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
            A  EV   + + + +   + E  ++ K++L +RL D +   E        L+K   RL  
Sbjct: 1366 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425

Query: 1438 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
            E++D  + +E        L+KKQR FD  L++  ++ +  + + E  Q+E   L  E F 
Sbjct: 1426 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1485

Query: 1498 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1557
            LK   EE    +  F ++  +L+ E+ D++ Q  +   ++ +++K  + LE +  + +  
Sbjct: 1486 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSA 1545

Query: 1558 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
            L+E   +++  E   LR ++E  +++    +++  +DEE+E+A+++ Q+ +  ++  L+ 
Sbjct: 1546 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA 1605

Query: 1618 EYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKR---LRKDLKRTKALLADAQLM 1671
            E   + +VLR K+++EG L  +  Q+   NR   E++K+   L+  LK T+  L DA   
Sbjct: 1606 ETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1665

Query: 1672 LDHLK-NSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTAL 1730
             D LK N A  +R    L+ +LEE         ++RK  E E+ +   ++  +    T+L
Sbjct: 1666 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1725

Query: 1731 EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---SRDLAQINDLQAQLEEAN 1787
              Q  +++ +  ++Q+ +EE  ++     +K K A+  A   + +L +  D  A LE   
Sbjct: 1726 INQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE--- 1782

Query: 1788 KEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERTQ----VKRL 1841
            + K+ +++ ++ LQ +++  EQ  +   K  + + EA++RELE  LE E+ +    VK +
Sbjct: 1783 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 1842

Query: 1842 ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
                 R+KE   +  E++   +  ++   +   +++   R  +E   +     ++  + +
Sbjct: 1843 RKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 1902

Query: 1902 HELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDE 1939
            HEL+   E  + A   +   L+   + IG  Q   ++E
Sbjct: 1903 HELDEAEERADIAESQVN-KLRAKSRDIGAKQKMHDEE 1939


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score =  511 bits (1315), Expect = e-144
 Identities = 431/1697 (25%), Positives = 811/1697 (47%), Gaps = 218/1697 (12%)

Query: 376  GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
            GKV  K +  GA + V +D V   N P  D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 58   GKVTAKTEA-GATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116

Query: 436  TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
            TY+G   + + P     VY+ +V+  ++G +R++  PHI++++  AY+ ML  R++QSI+
Sbjct: 117  TYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176

Query: 496  LLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYT----------LLEAFGNS 545
            + G SG+GKT + + ++QY ATIA     K   V   +   T          LLEAFGN+
Sbjct: 177  ITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNA 236

Query: 546  PTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACG 605
             T+ N N++RF + + + F   G++ASA I+T LLEK RV  +  +E ++++FY +++  
Sbjct: 237  KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMS-- 294

Query: 606  DGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKAC 662
                + +L    L   N +    +++ E    +     +L A   A+++LG + DE+ + 
Sbjct: 295  --NKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSI 352

Query: 663  WFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT 722
            + +  A+ H G     ++  E   +     E A KAAYL   +  +L  A+   + K G 
Sbjct: 353  YKLTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKAAYLQNLNSADLLKALCYPRVKVG- 410

Query: 723  LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSL 782
               +    +G     + +  G           +A  +Y ++F  +V+ +N+ L + Q   
Sbjct: 411  ---NEYVTKGQTVQQVYNAVG----------ALAKAVYDKMFLWMVTRINQQLDTKQPRQ 457

Query: 783  CSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIEL 842
              + ++D  GF+  +        S E+LC N+T ++LQ+ F+   FV E E YK+E IE 
Sbjct: 458  YFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511

Query: 843  AFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLF 902
             F D           +D A+   L+      ++  G+  +LEEE + P A++ +   +L+
Sbjct: 512  TFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLY 556

Query: 903  SYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRL 961
              +  +  +   Q P     KP  HF L H  GT  V+YN+ GWL+  K +P  +    L
Sbjct: 557  EQHLGKSNN--FQKPKPAKGKPEAHFSLIHYAGT--VDYNIAGWLDKNK-DPLNETVVGL 611

Query: 962  LQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSL 1021
             Q S  K ++ LF+G  G+     G   G +GG +           +F T  A  ++   
Sbjct: 612  YQKSAMKTLALLFVGATGAEAEAGG---GKKGGKKKG--------SSFQTVSALFRE--- 657

Query: 1022 CIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCE 1081
                   ++ L+  ++ +  HFV C +P                    +E   P      
Sbjct: 658  ------NLNKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA---- 687

Query: 1082 AGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYI 1141
                 ++  L+  QLR + +L+ +R+ R+G+P  +++++F++R+ VL      +      
Sbjct: 688  -----MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ---- 738

Query: 1142 VVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRG 1201
             +D ++A E+LL  +D++ +    G ++VFF+AG L  LEE RDE+ ++ +T  QA CRG
Sbjct: 739  FIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRG 798

Query: 1202 YLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261
            +LAR  ++K   +  +I C+Q N++    VK WPW KL+  ++PL++   +E+++ N  E
Sbjct: 799  FLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKE 858

Query: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321
            E ++ + +L K E +R EL      L    ++L  ++  E ++   A +  D     +++
Sbjct: 859  EFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQ 918

Query: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVR 1380
             E ++KE+  +  A  ++    E+   + +L    +E+  ++DD +       K E+   
Sbjct: 919  LEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKH 973

Query: 1381 EVDFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQ 1433
              +   K L +E    ++ +    + K+ L    ++ L DLQA+ ++    +  L K   
Sbjct: 974  ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK----VNTLTKAKI 1029

Query: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
            +L  ++ D +  LE ++    +LE+ +R+ + +L  A E     +  +++L  +      
Sbjct: 1030 KLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEF 1089

Query: 1494 EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKD 1553
            E   L+ ++E++        +K+  L+A ++++  +   + AS AK +KQ  DL  ++++
Sbjct: 1090 EMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149

Query: 1554 QEEELDEQAGT----IQM--------------LEQAKLRLEMEMERMRQTHSKEMESRDE 1595
              E L+E  G     I+M              LE+A L+ E     +R+ H+  +    E
Sbjct: 1150 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGE 1209

Query: 1596 EV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRDFES 1650
            ++   +  +Q  +K+  +M++++++   + + V + K  LE     L DQ++  +   E 
Sbjct: 1210 QIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEE 1269

Query: 1651 EKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAME 1710
            ++RL  DL   +A L                + E  +   QL+E +   +   + ++A  
Sbjct: 1270 QQRLINDLTAQRARL----------------QTESGEYSRQLDEKDTLVSQLSRGKQAFT 1313

Query: 1711 VEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVA 1767
             +IE+L  Q+++  KAK+AL   L   + + + ++ + EE+QE   EL   M K  + VA
Sbjct: 1314 QQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVA 1373

Query: 1768 Q------------------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFL- 1807
            Q                  A + LAQ + D +  +E  N +   L++  Q LQ++VE L 
Sbjct: 1374 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1433

Query: 1808 ---------------EQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852
                           +Q   DK L    E K +  ET  E E +Q K   SL++ L +  
Sbjct: 1434 IDVERTNAACAALDKKQRNFDKILA---EWKQKCEETHAELEASQ-KESRSLSTELFKIK 1489

Query: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLE 1912
                E  DQ        K +NK LQ+++ D  E++ E  ++  E  + K ++E +   L+
Sbjct: 1490 NAYEESLDQL----ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQ 1545

Query: 1913 AANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWL 1972
            AA +  +A L+    +I  +Q  + ++++S+ +  +  +E D ++D    + +  V+S  
Sbjct: 1546 AALEEAEASLEHEEGKILRIQLEL-NQVKSEVDRKI--AEKDEEIDQMKRNHIRIVESMQ 1602

Query: 1973 SKNKGPSKAASDDGSLK 1989
            S      ++ +D   LK
Sbjct: 1603 STLDAEIRSRNDAIRLK 1619



 Score =  194 bits (494), Expect = 6e-49
 Identities = 156/687 (22%), Positives = 334/687 (48%), Gaps = 47/687 (6%)

Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
            E+  R  ++++ ++++K E+ ++  N+L     RL++   E + +L DE++T    SQL 
Sbjct: 1250 EKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL-DEKDT--LVSQLS 1306

Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
              + A   + E+  ++L+ +  A       ++    +  L+R        ++ +A  E +
Sbjct: 1307 RGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQY----EEEQEAKAELQ 1362

Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
                +A  EV   + + + +   + E  ++ K++L +RL D +   E        L+K  
Sbjct: 1363 RAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTK 1422

Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492
            QRL  E++D  + +E        L+KKQR FD  L++  ++ +    + E  Q+E   L 
Sbjct: 1423 QRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLS 1482

Query: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVK 1552
             E F +K   EE    +    ++  +L+ E+ D++ Q ++    + +++K  + +E +  
Sbjct: 1483 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKS 1542

Query: 1553 DQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME 1612
            + +  L+E   +++  E   LR+++E+ +++    +++  +DEE+++ +++  + ++ M+
Sbjct: 1543 ELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQ 1602

Query: 1613 VQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML 1672
              L+ E   +   +R K+++EG L  +  Q+N  +  + + LR + + T+A+L D QL L
Sbjct: 1603 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR-NYRNTQAILKDTQLHL 1661

Query: 1673 DH-LKNSAPSKREIAQ-------LKNQLEESEFTCAAAVKARKAMEVEIED-------LH 1717
            D  L++    K ++A        L+ ++EE   T     ++RK  E E+ D       LH
Sbjct: 1662 DDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLH 1721

Query: 1718 LQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMKKHK---A 1764
             Q   +   K  LE  +S++Q E  +I       +E           M E +KK +   A
Sbjct: 1722 TQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781

Query: 1765 AVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLEQSMVDK- 1814
             + +  ++L Q + DLQ +L+EA         K+ Q+L+ +++ L+ +VE  ++  V+  
Sbjct: 1782 HLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAV 1841

Query: 1815 SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNK 1874
              + + E K++EL  + E +R  + RL+ L  +L+  ++    + ++     N    + +
Sbjct: 1842 KGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFR 1901

Query: 1875 RLQRQLRDTKEEMGELARKEAEASRKK 1901
            R+Q +L +  EE  ++A  +    R K
Sbjct: 1902 RIQHELEEA-EERADIAESQVNKLRVK 1927



 Score =  105 bits (262), Expect = 5e-22
 Identities = 137/611 (22%), Positives = 266/611 (43%), Gaps = 104/611 (17%)

Query: 1256 IRNKDEEIQQLRSKLEKA-EKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314
            +R + EE Q+ +++L++A  K  +E+     + E+   + T EL + +   + A +L DA
Sbjct: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKK--KLAQRLQDA 1404

Query: 1315 ETAERLRA-EKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL 1373
            E  E + A   +   L+     L+ ++E + ++V       AA    + + D    EW+ 
Sbjct: 1405 E--EHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQ 1462

Query: 1374 KYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQ 1433
            K E               E   +LE  Q+  R L   L  ++   EES   L+ LK++ +
Sbjct: 1463 KCE---------------ETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENK 1507

Query: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFD---SELSQAHEEAQ-----------REKL 1479
             L  E+ D    +     R HELEK +++ +   SEL  A EEA+           R +L
Sbjct: 1508 NLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQL 1567

Query: 1480 QREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVS---------------LEAELQ 1524
            +  +++ E D  +AE      Q++   + I    Q  +                +E +L 
Sbjct: 1568 ELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLN 1627

Query: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGT-------IQMLEQAKLRLEM 1577
            ++  Q +      A+  +  R+ +A +KD +  LD+   +       + M+E+    L+ 
Sbjct: 1628 EMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQA 1687

Query: 1578 EMERMRQTHSKEMESR---DEEVEEARQSCQ-------------KKLKQMEVQLEEEYED 1621
            E+E +R T  +   SR   ++E+ +A +  Q             KKL+    Q++ E ED
Sbjct: 1688 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMED 1747

Query: 1622 KQKVLREKRELEGKL-------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLML 1672
               +++E R  E K        A +++++ +    S   +R++K+L++T   + D Q  L
Sbjct: 1748 ---IIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRL 1801

Query: 1673 DHLKNSAPS---------KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723
            D  +  A           +  + +L+ ++E  +     AVK  +  E ++++L  Q ++ 
Sbjct: 1802 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEED 1861

Query: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QI 1776
             K    L++ + +LQ +    + + EE +E  N  + K     H+   A+   D+A  Q+
Sbjct: 1862 RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQV 1921

Query: 1777 NDLQAQLEEAN 1787
            N L+ +  E +
Sbjct: 1922 NKLRVKSREVH 1932



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 68/301 (22%), Positives = 147/301 (48%), Gaps = 11/301 (3%)

Query: 1257 RNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAET 1316
            RN    ++  +  L+ A + + +L+     +E R + L +E+ + R T E   +      
Sbjct: 1648 RNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1707

Query: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLKY 1375
             E L A + ++ L TQ  +L    + +E ++        ++I GE++D          K 
Sbjct: 1708 QELLDASERVQLLHTQNTSLINTKKKLETDI--------SQIQGEMEDIIQEARNAEEKA 1759

Query: 1376 ERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQR 1434
            ++A+ +     + L++E +    +E+  K+ LE+ + DLQ   +E+++ AL+  KK+ Q+
Sbjct: 1760 KKAITDAAMMAEELKKEQDTSAHLERM-KKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1818

Query: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494
            L A +++ +  +E +Q RN E  K  R+ + ++ +   + + ++    +LQ   D L A+
Sbjct: 1819 LEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAK 1878

Query: 1495 AFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ 1554
              S K+Q EE +        K   ++ EL++   +    E+ + K++ + R++  K+  +
Sbjct: 1879 VKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISE 1938

Query: 1555 E 1555
            E
Sbjct: 1939 E 1939



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 68/267 (25%), Positives = 125/267 (46%), Gaps = 44/267 (16%)

Query: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286
            ++ + E +      EI++LR+ LE+ E+ R     EL   S+R                 
Sbjct: 1674 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1733

Query: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340
            LE+ IS++  E+ D     RN  E A + +   A  AE L+ E   ++     + +KK +
Sbjct: 1734 LETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNL 1790

Query: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399
            E   ++ ++ RL  A ++  +      GG+ ++ K E  VRE++      + E E K  V
Sbjct: 1791 E-QTVKDLQHRLDEAEQLALK------GGKKQIQKLEARVRELEG-----EVESEQKRNV 1838

Query: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458
            E  +  R+ ER++ +L   +EE ++ + +L+    +L A+++  K   E  + +++    
Sbjct: 1839 EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLS 1898

Query: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485
            K RR   EL +A E A   + Q  KL+
Sbjct: 1899 KFRRIQHELEEAEERADIAESQVNKLR 1925



 Score = 35.0 bits (79), Expect = 0.75
 Identities = 36/172 (20%), Positives = 79/172 (45%), Gaps = 16/172 (9%)

Query: 1181 EEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLF 1240
            E ++++ TS +L   +      +     +  + + LA++  +K I+K           L 
Sbjct: 1772 ELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK-----------LE 1820

Query: 1241 TTVRPLIEVQLSEEQIRNKDEEIQQLRS---KLEKAEKERNELRLNSDRLESRISELTSE 1297
              VR L E ++  EQ RN  E ++ LR    K+++   +  E R N  RL+  + +L ++
Sbjct: 1821 ARVREL-EGEVESEQKRNV-EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAK 1878

Query: 1298 LTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
            +   +   E A +  +   ++  R + E++E + + D  + Q+  + ++  E
Sbjct: 1879 VKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSRE 1930


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score =  507 bits (1306), Expect = e-143
 Identities = 411/1671 (24%), Positives = 810/1671 (48%), Gaps = 205/1671 (12%)

Query: 385  DGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLV 444
            D  +L ++ D V   N P  D++ED+A + +L+E +VL+ L++RY A +++TY+G   + 
Sbjct: 66   DDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVT 125

Query: 445  LGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGK 504
            + P     VY  +V+  ++G +R++  PHI++++  AY+ ML  R +QSI++ G SG+GK
Sbjct: 126  VNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGK 185

Query: 505  TTSCQHLVQYLATIAGISGNKVFSVEKWQALYT----------LLEAFGNSPTIINGNAT 554
            T + + ++QY ATIA ++G+K    +  +   T          LLEAFGN+ T+ N N++
Sbjct: 186  TVNTKRVIQYFATIA-VTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSS 244

Query: 555  RFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELH 614
            RF + + + F   G++ASA I+T LLEK RV  + +SE ++++FY +++      + EL 
Sbjct: 245  RFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMS----NKKPELI 300

Query: 615  LNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKACWFILAAIYH 671
               L   N F    +++ E    +     +L A   A+ +LG S +E+   + +  A+ H
Sbjct: 301  DLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMH 360

Query: 672  LGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQ 731
             G     ++  E   +     E A KA YL+G +  E+   +   + K G    +    +
Sbjct: 361  YGNMKFKQKQREEQAEPDGT-EVADKAGYLMGLNSAEMLKGLCCPRVKVG----NEYVTK 415

Query: 732  GPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTP 791
            G     + +  G           +A  +Y ++F  +V+ +N+ L + Q     + ++D  
Sbjct: 416  GQNVQQVTNSVG----------ALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIA 465

Query: 792  GFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPT 851
            GF+  +        S E+LC N+T ++LQ+ F+   FV E E YK+E IE  F D     
Sbjct: 466  GFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDF---- 515

Query: 852  DDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGD 911
                  +D A+   L+      ++  G+  +LEEE + P A++ +   +L+  +  +  +
Sbjct: 516  -----GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 564

Query: 912  KKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIIS 971
             +   P    ++  HF L H  GT  V+YN+ GWL+  K +P  +    L Q S  K++S
Sbjct: 565  FQKPKPAKGKAEA-HFSLVHYAGT--VDYNIAGWLDKNK-DPLNETVVGLYQKSSLKLLS 620

Query: 972  NLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDA 1031
             LF   AG+ T       G  GGS+   ++  S  +T    ++AV +++L        + 
Sbjct: 621  FLFSNYAGAET-------GDSGGSKKGGKKKGSSFQT----VSAVFRENL--------NK 661

Query: 1032 LIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPL 1091
            L+  ++ +  HFV C +P                    +E   P           +D  L
Sbjct: 662  LMTNLRSTHPHFVRCLIP--------------------NETKTPG---------VMDHYL 692

Query: 1092 LRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEE 1151
            +  QLR + +L+ +R+ R+G+P  +++++F++R+ +L      +       +D + A E+
Sbjct: 693  VMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQ----FIDSKNASEK 748

Query: 1152 LLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKR 1211
            LL  +D+++     G ++VFF+AG L  LEE RDE+    +T  QA CRGYL R  FKK 
Sbjct: 749  LLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKM 808

Query: 1212 KIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLE 1271
              +  +I C+Q NI+    VK WPW  LF  ++PL++   +E+++    E+ ++ + +L 
Sbjct: 809  MERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELA 868

Query: 1272 KAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQT 1331
            ++E  R EL      L    ++L  ++  E      A +  +     ++  E ++KEL  
Sbjct: 869  RSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELT- 927

Query: 1332 QYDALKKQMEVMEMEVMEARLI--RAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRL 1389
              + L+++ E+    V + R +  + + +  ++DD +       K E+     +   K L
Sbjct: 928  --ERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLEL---TLTKVEKEKHATENKVKNL 982

Query: 1390 QQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 1442
             +E    E+ +    + K+ L    ++ L DLQ + E+    L ++  K ++ T +L+ +
Sbjct: 983  SEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVE-EDKVNGLIKINAKLEQQTDDLEGS 1041

Query: 1443 KLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDMLLAEAFSLK 1499
               LE ++    +LE+ +R+ + +L  + E   + + +K Q E+  ++K+  L++   L+
Sbjct: 1042 ---LEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQ---LQ 1095

Query: 1500 QQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELD 1559
             +++++ +    F +K+  L+A ++++  +   +    AK++KQ  DL  ++++  E L+
Sbjct: 1096 AKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLE 1155

Query: 1560 EQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY 1619
            E +G      +   + E E ++MR    +++E    + E    + +KK      +L E+ 
Sbjct: 1156 EASGATSAQIEMNKKREAEFQKMR----RDLEEATLQHEATAATLRKKQADSVAELGEQI 1211

Query: 1620 ED----KQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLAD-------- 1667
            ++    KQK+ +EK EL+ ++  ++  +     E+  + + +++RT   + D        
Sbjct: 1212 DNLQRVKQKLEKEKSELKMEIDDMASNI-----EALSKSKSNIERTCRTVEDQFSEIKAK 1266

Query: 1668 ----AQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723
                 QL+ D     A  + +  +L +++EE E   +   K+++A+  ++E+L  Q+++ 
Sbjct: 1267 DEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEE 1326

Query: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVAQ------------ 1768
             KAK A+   L   + + + ++ + EE+QE   EL   + K  + VAQ            
Sbjct: 1327 TKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQR 1386

Query: 1769 ------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVE----FLEQSMVDKSLV 1817
                  A + LAQ + + +   E AN +   L++  Q LQ +VE     LE+S    + +
Sbjct: 1387 TEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATL 1446

Query: 1818 SRQEAK----IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQN 1873
             +++      + E + +L+  + +++  +  +  L   + K+    ++ +      + +N
Sbjct: 1447 DKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRREN 1506

Query: 1874 KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933
            K LQ ++ D  E++ E  +   EA + K  +E +   L+ A + ++  L+    +I  +Q
Sbjct: 1507 KNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQ 1566

Query: 1934 ---AAIEDEM-----ESDENEDLINSEG-------DSDVDSELEDRVDGVK 1969
               + ++ E+     E DE  + +            S +D+E+  R D ++
Sbjct: 1567 LELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALR 1617



 Score =  190 bits (483), Expect = 1e-47
 Identities = 171/701 (24%), Positives = 332/701 (47%), Gaps = 64/701 (9%)

Query: 1247 IEVQLSEEQIRNKDEE----IQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDER 1302
            +E Q SE  I+ KDE+    I  L  +  + + +  EL    +  ES IS+LT       
Sbjct: 1256 VEDQFSE--IKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALT 1313

Query: 1303 NTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AEINGE 1361
               E   + ++ ET  +      ++  +   D L++Q E  E +  +A L RA ++ N E
Sbjct: 1314 QQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYE--EEQEAKAELQRALSKANSE 1371

Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
            V       +WR KYE    +              + E  ++ K++L +RL + + ++E +
Sbjct: 1372 V------AQWRTKYETDAIQ--------------RTEELEEAKKKLAQRLQEAEENTETA 1411

Query: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
                  L+K  QRL  E++D    LE        L+KKQR FD  L++  ++    + + 
Sbjct: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471

Query: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1541
            E  Q+E   L  E F ++   EE    +    ++  +L+ E+ D++ Q ++   +L + +
Sbjct: 1472 EAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAE 1531

Query: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601
            K  + +E +  D +  L+E  G+++  E   LR+++E+ +++    +++  +DEE+E+ +
Sbjct: 1532 KTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLK 1591

Query: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKDL 1658
            ++ Q+  + ++  L+ E   +   LR K+++EG L  +  Q+   NR+  E++K LR   
Sbjct: 1592 RNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLR--- 1648

Query: 1659 KRTKALLADAQLMLDH-LKNSAPSKREIA-------QLKNQLEESEFTCAAAVKARKAME 1710
               +  L D+QL LD  L+++   K ++A        L  +LEE +       + R+  E
Sbjct: 1649 -TVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSE 1707

Query: 1711 VEIED-------LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHK 1763
             E+ D       LH Q   +   K  LE  +++ Q    E++N ++E + +  E  KK  
Sbjct: 1708 QELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQA---EVENSIQESR-NAEEKAKKAI 1763

Query: 1764 AAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQE 1821
               A  + +L +  D  A LE   + K+ L++ ++ LQ +++  EQ  +   K  + + E
Sbjct: 1764 TDAAMMAEELKKEQDTSAHLE---RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820

Query: 1822 AKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLR 1881
             ++RELE  L+ E+ +       A + +  ++++T + ++      R ++   +LQ +++
Sbjct: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880

Query: 1882 DTK---EEMGELARKEAEASRK-KHELEMDLESLEAANQSL 1918
              K   EE  E A  +    R+ +HELE   E  + A   +
Sbjct: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQV 1921



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 60/304 (19%), Positives = 145/304 (47%), Gaps = 9/304 (2%)

Query: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 1311
            +++ +R    +++  +  L+ A +   +L+     +E R   L  EL + +   E   + 
Sbjct: 1643 TQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERT 1702

Query: 1312 LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEW 1371
                  E L A   ++ L +Q  +L    + +E ++ + +    AE+   + +     E 
Sbjct: 1703 RRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQ----AEVENSIQESRNAEE- 1757

Query: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKK 1430
              K ++A+ +     + L++E +    +E+  K+ LE+ + DLQ   +E+++ AL+  KK
Sbjct: 1758 --KAKKAITDAAMMAEELKKEQDTSAHLERM-KKNLEQTVKDLQHRLDEAEQLALKGGKK 1814

Query: 1431 KCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDM 1490
            + Q+L   +++ +  L+ +Q R  E  K   +++ ++ +   +A+ +     +LQ   D 
Sbjct: 1815 QIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDK 1874

Query: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550
            L A+  S K+Q EE +        +   ++ EL++ + +    E+ + K++ + RD+ ++
Sbjct: 1875 LQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQ 1934

Query: 1551 VKDQ 1554
              ++
Sbjct: 1935 KMEE 1938



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 109/534 (20%), Positives = 222/534 (41%), Gaps = 63/534 (11%)

Query: 1103 DAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSS 1162
            D MR   + +       + +R FD +     +K   +     E  A ++    L  E   
Sbjct: 1431 DLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQA---ELEAAQKESRSLSTELFK 1487

Query: 1163 CCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQ 1222
                   V  +  TL R  +   E+ S +LT  Q A  G   ++  K +K+ +     +Q
Sbjct: 1488 MRNAYEEVVDQLETLRRENKNLQEEIS-DLTE-QIAETGKNLQEAEKTKKLVEQEKSDLQ 1545

Query: 1223 KNIKKNKGVKDWPWWKLFTTVRPLIEVQLS-EEQIRNKDEEIQQLRSKLEKAEKERN--- 1278
              +++ +G  +    K+      L +V+   + ++  KDEEI+QL+   ++A +      
Sbjct: 1546 VALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVL 1605

Query: 1279 --ELRLNSDRLESRISELTSELTD-ERNTGESASQLLDAETAERLRA-EKEMKELQTQYD 1334
              E+R  +D L  +  ++  +L + E   G S  Q+  AET + LR  + ++K+ Q   D
Sbjct: 1606 DAEIRSRNDALRLK-KKMEGDLNEMEIQLGHSNRQM--AETQKHLRTVQGQLKDSQLHLD 1662

Query: 1335 A-------LKKQMEVME---------MEVMEARLIRAAEINGEVDDD--DAGGEWRLKYE 1376
                    LK+Q+ ++E         +E M+  L +        + +  DA    +L + 
Sbjct: 1663 DALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHS 1722

Query: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436
            +    ++ TKK+L+ +         Q + ++E  + + +   E++++A+       + L 
Sbjct: 1723 QNTSLIN-TKKKLEADIA-------QCQAEVENSIQESRNAEEKAKKAITDAAMMAEELK 1774

Query: 1437 AELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF 1496
             E QDT  HLE        ++K   +   +L    +EA++  L+  K Q +K  L     
Sbjct: 1775 KE-QDTSAHLE-------RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK--LENRVR 1824

Query: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASL-----------AKVKKQLR 1545
             L+ +L+ +    A   +     E ++++++ Q  +D  ++           AKVK   R
Sbjct: 1825 ELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKR 1884

Query: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
              E   +    +L         LE+A  R ++   ++ +  +K  +   +++EE
Sbjct: 1885 QAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score =  506 bits (1304), Expect = e-143
 Identities = 428/1678 (25%), Positives = 814/1678 (48%), Gaps = 226/1678 (13%)

Query: 376  GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
            GKV VK +  GA L V +D V   N P  D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 58   GKVTVKTE-GGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116

Query: 436  TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
            TY+G   + + P     VY  +V+  ++G +R++  PHI++++  AY+ ML  R++QSI+
Sbjct: 117  TYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176

Query: 496  LLGSSGSGKTTSCQHLVQYLATIA--------GISGNKVFSVEKWQALYT--LLEAFGNS 545
            + G SG+GKT + + ++QY ATIA         I+  K+    + Q +    LLEAFGN+
Sbjct: 177  ITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNA 236

Query: 546  PTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACG 605
             T+ N N++RF + + + F   G++ASA I+T LLEK RV  +  +E ++++FY + +  
Sbjct: 237  KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITS-- 294

Query: 606  DGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKAC 662
                + EL    L   N +    +++ E    +     +L A   A+ +LG + +E+ + 
Sbjct: 295  --NKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSI 352

Query: 663  WFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT 722
            + +  A+ H G     ++  E   +     E A KAAYL   +  +L  A+   + K G 
Sbjct: 353  YKLTGAVMHYGNLKFKQKQREEQAEPDGT-EVADKAAYLQSLNSADLLKALCYPRVKVG- 410

Query: 723  LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSL 782
               +    +G     + +  G           +A  +Y ++F  +V+ +N+ L + Q   
Sbjct: 411  ---NEYVTKGQTVEQVSNAVG----------ALAKAVYEKMFLWMVARINQQLDTKQPRQ 457

Query: 783  CSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIEL 842
              + ++D  GF+  +        S E+LC N+T ++LQ+ F+   FV E E YK+E IE 
Sbjct: 458  YFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511

Query: 843  AFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLF 902
             F D           +D A+   L+      ++  G+  +LEEE + P A++ +   +L+
Sbjct: 512  TFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLY 556

Query: 903  SYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRL 961
              +  +  +   Q P +   K   HF L H  G   V+YN+TGWL   K +P  +    L
Sbjct: 557  DQHLGKSAN--FQKPKVVKGKAEAHFALIHYAGV--VDYNITGWLEKNK-DPLNETVVGL 611

Query: 962  LQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSL 1021
             Q S  K ++ LF G    A    G  AG  GG++   ++  S  +T    ++A+ +++L
Sbjct: 612  YQKSAMKTLAQLFSG----AQTAEGEGAG--GGAKKGGKKKGSSFQT----VSALFRENL 661

Query: 1022 CIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCE 1081
                    + L+  ++ +  HFV C +P                    +E   P      
Sbjct: 662  --------NKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA---- 689

Query: 1082 AGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYI 1141
                 ++  L+  QLR + +L+ +R+ R+G+P  +++++F++R+ VL      +      
Sbjct: 690  -----MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ---- 740

Query: 1142 VVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRG 1201
             +D ++A E+LL  +D++ +    G ++VFF+AG L  LEE RD++ ++ +T  QA CRG
Sbjct: 741  FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800

Query: 1202 YLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261
            +LAR  +++   +  AI C+Q NI+    VK WPW KLF  ++PL++   +E+++    E
Sbjct: 801  FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860

Query: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321
            E Q+++ +L K+E +R EL      L    ++L  ++  E      A +  D     +++
Sbjct: 861  EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920

Query: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVR 1380
             E ++KE+  +  A  ++    E+   + +L    +E+  ++DD +       K E+   
Sbjct: 921  LEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKH 975

Query: 1381 EVDFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQ 1433
              +   K L +E    ++ +    + K+ L    ++ L DLQA+ ++    +  L K   
Sbjct: 976  ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK----VNTLTKAKI 1031

Query: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDM 1490
            +L  ++ D +  LE ++    +LE+ +R+ + +L  A E   + + EK Q ++  ++K+ 
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091

Query: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550
               E  +L+ ++E++        +K+  L+A ++++  +   + AS AK +KQ  DL  +
Sbjct: 1092 ---EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1148

Query: 1551 VKDQEEELDEQAGT----IQM--------------LEQAKLRLEMEMERMRQTHSKEMES 1592
            +++  E L+E  G     I+M              LE+A L+ E     +R+ H+  +  
Sbjct: 1149 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAE 1208

Query: 1593 RDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRD 1647
              E++   +  +Q  +K+  +M++++++   + + V + K  LE    TL DQ++  +  
Sbjct: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSK 1268

Query: 1648 FESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARK 1707
             E ++RL  DL   +  L                + E  +   QL+E E   +   + ++
Sbjct: 1269 EEEQQRLINDLTAQRGRL----------------QTESGEFSRQLDEKEALVSQLSRGKQ 1312

Query: 1708 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVA 1767
            A   +IE+L  Q+++  KAK AL   L   + + + ++ + EE+QE   EL +    A++
Sbjct: 1313 AFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQR----ALS 1368

Query: 1768 QASRDLAQ-----INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEA 1822
            +A+ ++AQ       D   + EE  + K++L ++LQA +  VE      V+    S ++ 
Sbjct: 1369 KANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE-----AVNAKCASLEKT 1423

Query: 1823 KIRELETRLEFERTQVKRLESLASRL---KENMEKLTEERDQRIAAENREKEQNKR---- 1875
            K R L+  +E     V+R  +  + L   + N +K+  E  Q+    + E E +++    
Sbjct: 1424 KQR-LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARS 1482

Query: 1876 ---------------------LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA 1914
                                 L+R+ ++ ++E+ +L  + AE  ++ HELE   + +E  
Sbjct: 1483 LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE 1542

Query: 1915 NQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD---SELEDRVDGVK 1969
               LQA L+       + +A++E E        L  ++  S+VD   +E ++ +D +K
Sbjct: 1543 KCELQAALE-------EAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLK 1593



 Score =  186 bits (471), Expect = 3e-46
 Identities = 158/694 (22%), Positives = 330/694 (47%), Gaps = 61/694 (8%)

Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
            E+  R  ++++ +L+SK E+ ++  N+L     RL++   E + +L DE+      SQL 
Sbjct: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL-DEKEA--LVSQLS 1308

Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
              + A   + E+  ++L+ +  A       ++    +  L+R        ++ ++  E +
Sbjct: 1309 RGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQY----EEEQESKAELQ 1364

Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
                +A  EV   + + + +   + E  ++ K++L +RL   +   E        L+K  
Sbjct: 1365 RALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK 1424

Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492
            QRL  E++D  L +E        L+KKQR FD  L++  ++ +    + E  Q+E   L 
Sbjct: 1425 QRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLG 1484

Query: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDEASLAKVKKQLR---- 1545
             E F +K   EE    +    ++  +L+ E+ D++ Q     K    L K+KKQ+     
Sbjct: 1485 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKC 1544

Query: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1605
            +L+A +++ E  L+ + G I       LR+++E+ +++    +++  +DEE+++ +++  
Sbjct: 1545 ELQAALEEAEASLEHEEGKI-------LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597

Query: 1606 KKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665
            + ++ M+  L+ E   +   +R K+++EG L  +  Q+N  +  + + LR + + T+ +L
Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR-NYRNTQGIL 1656

Query: 1666 ADAQLMLDH-LKNSAPSKREIAQ-------LKNQLEESEFTCAAAVKARKAMEVEIED-- 1715
             D Q+ LD  L++    K ++A        L+ ++EE   T     ++RK  E E+ D  
Sbjct: 1657 KDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDAS 1716

Query: 1716 -----LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMK 1760
                 LH Q   +   K  LE  +S++Q E  +I       +E           M E +K
Sbjct: 1717 ERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELK 1776

Query: 1761 KHK---AAVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLE 1808
            K +   A + +  +++ Q + DLQ +L+EA         K+ Q+L+ +++ L+ +VE  +
Sbjct: 1777 KEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836

Query: 1809 QSMVDK-SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAEN 1867
            +   +    + + E +++EL  + E +R  + RL+ L  +L+  ++    + ++     N
Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896

Query: 1868 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
                + ++LQ +L +  EE  ++A  +    R K
Sbjct: 1897 TNLAKFRKLQHELEEA-EERADIAESQVNKLRVK 1929



 Score =  103 bits (257), Expect = 2e-21
 Identities = 124/598 (20%), Positives = 260/598 (43%), Gaps = 78/598 (13%)

Query: 1256 IRNKDEEIQQLRSKLEKA-EKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314
            +R + EE Q+ +++L++A  K   E+     + E+   + T EL + +   +  +Q L A
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK---KKLAQRLQA 1405

Query: 1315 ETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLK 1374
                      +   L+     L+ ++E + ++V       AA    + + D    EW+ K
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465

Query: 1375 YERAVREVDFTKKRLQ-------------QEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
             E    E++ ++K  +             +E  D+LE  ++  + L++ + DL     E 
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525

Query: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
             + + +L+K  +++  E  + +  LE  +      E K  R   EL+Q   E  R+  ++
Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1585

Query: 1482 EKLQREKDMLLAEAFSLKQQLEEK-DMDIAGFTQKV---VSLEAELQDISSQESKDEASL 1537
            ++   E D L      + + ++   D +I      +     +E +L ++  Q +      
Sbjct: 1586 DE---EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642

Query: 1538 AKVKKQLRDLEAKVKDQEEELDEQAGT-------IQMLEQAKLRLEMEMERMRQTHSKEM 1590
            A+  +  R+ +  +KD +  LD+   +       + M+E+    L+ E+E +R T  +  
Sbjct: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1702

Query: 1591 ESR---DEEVEEARQSCQ-------------KKLKQMEVQLEEEYEDKQKVLREKRELEG 1634
             SR   ++E+ +A +  Q             KKL+    Q++ E ED   +L+E R  E 
Sbjct: 1703 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMED---ILQEARNAEE 1759

Query: 1635 KL-------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLMLDHLKNSAPS---- 1681
            K        A +++++ +    S   +R++K++++T   + D QL LD  +  A      
Sbjct: 1760 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---VKDLQLRLDEAEQLALKGGKK 1816

Query: 1682 -----KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSR 1736
                 +  + +L+ ++E  +   A AVK  +  E  +++L  Q ++  K    L++ + +
Sbjct: 1817 QIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDK 1876

Query: 1737 LQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QINDLQAQLEEAN 1787
            LQ +    + + EE +E  N  + K     H+   A+   D+A  Q+N L+ +  E +
Sbjct: 1877 LQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVH 1934



 Score = 81.6 bits (200), Expect = 7e-15
 Identities = 68/301 (22%), Positives = 146/301 (48%), Gaps = 11/301 (3%)

Query: 1257 RNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAET 1316
            RN    ++  +  L+ A + + +L+     +E R + L +E+ + R T E   +      
Sbjct: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709

Query: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLKY 1375
             E L A + ++ L TQ  +L    + +E ++        +++ GE++D          K 
Sbjct: 1710 QELLDASERVQLLHTQNTSLINTKKKLETDI--------SQMQGEMEDILQEARNAEEKA 1761

Query: 1376 ERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQR 1434
            ++A+ +     + L++E +    +E+  K+ +E+ + DLQ   +E+++ AL+  KK+ Q+
Sbjct: 1762 KKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820

Query: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494
            L A +++ +  +E +Q RN E  K  R+ +  + +   + + ++    +LQ   D L A+
Sbjct: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880

Query: 1495 AFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ 1554
              S K+Q EE +        K   L+ EL++   +    E+ + K++ + R++  KV  +
Sbjct: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISE 1940

Query: 1555 E 1555
            E
Sbjct: 1941 E 1941



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 68/267 (25%), Positives = 124/267 (46%), Gaps = 44/267 (16%)

Query: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286
            ++ + E +      EI++LR+ LE+ E+ R     EL   S+R                 
Sbjct: 1676 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735

Query: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340
            LE+ IS++  E+ D     RN  E A + +   A  AE L+ E   ++     + +KK M
Sbjct: 1736 LETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNM 1792

Query: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399
            E   ++ ++ RL  A ++  +      GG+ ++ K E  VRE++      + E E K   
Sbjct: 1793 E-QTVKDLQLRLDEAEQLALK------GGKKQIQKLEARVRELEG-----EVESEQKRNA 1840

Query: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458
            E  +  R+ ERR+ +L   +EE ++ + +L+    +L A+++  K   E  + +++    
Sbjct: 1841 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLA 1900

Query: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485
            K R+   EL +A E A   + Q  KL+
Sbjct: 1901 KFRKLQHELEEAEERADIAESQVNKLR 1927



 Score = 34.7 bits (78), Expect = 0.98
 Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 6/143 (4%)

Query: 1210 KRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRS- 1268
            ++ ++DL +R  +      KG K     KL   VR L E ++  EQ RN  E ++ LR  
Sbjct: 1793 EQTVKDLQLRLDEAEQLALKGGKK-QIQKLEARVREL-EGEVESEQKRNA-EAVKGLRKH 1849

Query: 1269 --KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEM 1326
              ++++   +  E R N  RL+  + +L +++   +   E A +  +   A+  + + E+
Sbjct: 1850 ERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909

Query: 1327 KELQTQYDALKKQMEVMEMEVME 1349
            +E + + D  + Q+  + ++  E
Sbjct: 1910 EEAEERADIAESQVNKLRVKSRE 1932


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score =  506 bits (1304), Expect = e-143
 Identities = 428/1678 (25%), Positives = 814/1678 (48%), Gaps = 226/1678 (13%)

Query: 376  GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
            GKV VK +  GA L V +D V   N P  D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 58   GKVTVKTE-GGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116

Query: 436  TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
            TY+G   + + P     VY  +V+  ++G +R++  PHI++++  AY+ ML  R++QSI+
Sbjct: 117  TYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176

Query: 496  LLGSSGSGKTTSCQHLVQYLATIA--------GISGNKVFSVEKWQALYT--LLEAFGNS 545
            + G SG+GKT + + ++QY ATIA         I+  K+    + Q +    LLEAFGN+
Sbjct: 177  ITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNA 236

Query: 546  PTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACG 605
             T+ N N++RF + + + F   G++ASA I+T LLEK RV  +  +E ++++FY + +  
Sbjct: 237  KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITS-- 294

Query: 606  DGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKAC 662
                + EL    L   N +    +++ E    +     +L A   A+ +LG + +E+ + 
Sbjct: 295  --NKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSI 352

Query: 663  WFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT 722
            + +  A+ H G     ++  E   +     E A KAAYL   +  +L  A+   + K G 
Sbjct: 353  YKLTGAVMHYGNLKFKQKQREEQAEPDGT-EVADKAAYLQSLNSADLLKALCYPRVKVG- 410

Query: 723  LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSL 782
               +    +G     + +  G           +A  +Y ++F  +V+ +N+ L + Q   
Sbjct: 411  ---NEYVTKGQTVEQVSNAVG----------ALAKAVYEKMFLWMVARINQQLDTKQPRQ 457

Query: 783  CSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIEL 842
              + ++D  GF+  +        S E+LC N+T ++LQ+ F+   FV E E YK+E IE 
Sbjct: 458  YFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511

Query: 843  AFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLF 902
             F D           +D A+   L+      ++  G+  +LEEE + P A++ +   +L+
Sbjct: 512  TFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLY 556

Query: 903  SYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRL 961
              +  +  +   Q P +   K   HF L H  G   V+YN+TGWL   K +P  +    L
Sbjct: 557  DQHLGKSAN--FQKPKVVKGKAEAHFALIHYAGV--VDYNITGWLEKNK-DPLNETVVGL 611

Query: 962  LQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSL 1021
             Q S  K ++ LF G    A    G  AG  GG++   ++  S  +T    ++A+ +++L
Sbjct: 612  YQKSAMKTLAQLFSG----AQTAEGEGAG--GGAKKGGKKKGSSFQT----VSALFRENL 661

Query: 1022 CIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCE 1081
                    + L+  ++ +  HFV C +P                    +E   P      
Sbjct: 662  --------NKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA---- 689

Query: 1082 AGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYI 1141
                 ++  L+  QLR + +L+ +R+ R+G+P  +++++F++R+ VL      +      
Sbjct: 690  -----MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ---- 740

Query: 1142 VVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRG 1201
             +D ++A E+LL  +D++ +    G ++VFF+AG L  LEE RD++ ++ +T  QA CRG
Sbjct: 741  FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800

Query: 1202 YLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261
            +LAR  +++   +  AI C+Q NI+    VK WPW KLF  ++PL++   +E+++    E
Sbjct: 801  FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860

Query: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321
            E Q+++ +L K+E +R EL      L    ++L  ++  E      A +  D     +++
Sbjct: 861  EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920

Query: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVR 1380
             E ++KE+  +  A  ++    E+   + +L    +E+  ++DD +       K E+   
Sbjct: 921  LEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKH 975

Query: 1381 EVDFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQ 1433
              +   K L +E    ++ +    + K+ L    ++ L DLQA+ ++    +  L K   
Sbjct: 976  ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK----VNTLTKAKI 1031

Query: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDM 1490
            +L  ++ D +  LE ++    +LE+ +R+ + +L  A E   + + EK Q ++  ++K+ 
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091

Query: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550
               E  +L+ ++E++        +K+  L+A ++++  +   + AS AK +KQ  DL  +
Sbjct: 1092 ---EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1148

Query: 1551 VKDQEEELDEQAGT----IQM--------------LEQAKLRLEMEMERMRQTHSKEMES 1592
            +++  E L+E  G     I+M              LE+A L+ E     +R+ H+  +  
Sbjct: 1149 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAE 1208

Query: 1593 RDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRD 1647
              E++   +  +Q  +K+  +M++++++   + + V + K  LE    TL DQ++  +  
Sbjct: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSK 1268

Query: 1648 FESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARK 1707
             E ++RL  DL   +  L                + E  +   QL+E E   +   + ++
Sbjct: 1269 EEEQQRLINDLTAQRGRL----------------QTESGEFSRQLDEKEALVSQLSRGKQ 1312

Query: 1708 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVA 1767
            A   +IE+L  Q+++  KAK AL   L   + + + ++ + EE+QE   EL +    A++
Sbjct: 1313 AFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQR----ALS 1368

Query: 1768 QASRDLAQ-----INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEA 1822
            +A+ ++AQ       D   + EE  + K++L ++LQA +  VE      V+    S ++ 
Sbjct: 1369 KANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE-----AVNAKCASLEKT 1423

Query: 1823 KIRELETRLEFERTQVKRLESLASRL---KENMEKLTEERDQRIAAENREKEQNKR---- 1875
            K R L+  +E     V+R  +  + L   + N +K+  E  Q+    + E E +++    
Sbjct: 1424 KQR-LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARS 1482

Query: 1876 ---------------------LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA 1914
                                 L+R+ ++ ++E+ +L  + AE  ++ HELE   + +E  
Sbjct: 1483 LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE 1542

Query: 1915 NQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD---SELEDRVDGVK 1969
               LQA L+       + +A++E E        L  ++  S+VD   +E ++ +D +K
Sbjct: 1543 KCELQAALE-------EAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLK 1593



 Score =  186 bits (471), Expect = 3e-46
 Identities = 158/694 (22%), Positives = 330/694 (47%), Gaps = 61/694 (8%)

Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
            E+  R  ++++ +L+SK E+ ++  N+L     RL++   E + +L DE+      SQL 
Sbjct: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL-DEKEA--LVSQLS 1308

Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
              + A   + E+  ++L+ +  A       ++    +  L+R        ++ ++  E +
Sbjct: 1309 RGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQY----EEEQESKAELQ 1364

Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
                +A  EV   + + + +   + E  ++ K++L +RL   +   E        L+K  
Sbjct: 1365 RALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK 1424

Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492
            QRL  E++D  L +E        L+KKQR FD  L++  ++ +    + E  Q+E   L 
Sbjct: 1425 QRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLG 1484

Query: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDEASLAKVKKQLR---- 1545
             E F +K   EE    +    ++  +L+ E+ D++ Q     K    L K+KKQ+     
Sbjct: 1485 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKC 1544

Query: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1605
            +L+A +++ E  L+ + G I       LR+++E+ +++    +++  +DEE+++ +++  
Sbjct: 1545 ELQAALEEAEASLEHEEGKI-------LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597

Query: 1606 KKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665
            + ++ M+  L+ E   +   +R K+++EG L  +  Q+N  +  + + LR + + T+ +L
Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR-NYRNTQGIL 1656

Query: 1666 ADAQLMLDH-LKNSAPSKREIAQ-------LKNQLEESEFTCAAAVKARKAMEVEIED-- 1715
             D Q+ LD  L++    K ++A        L+ ++EE   T     ++RK  E E+ D  
Sbjct: 1657 KDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDAS 1716

Query: 1716 -----LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMK 1760
                 LH Q   +   K  LE  +S++Q E  +I       +E           M E +K
Sbjct: 1717 ERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELK 1776

Query: 1761 KHK---AAVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLE 1808
            K +   A + +  +++ Q + DLQ +L+EA         K+ Q+L+ +++ L+ +VE  +
Sbjct: 1777 KEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836

Query: 1809 QSMVDK-SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAEN 1867
            +   +    + + E +++EL  + E +R  + RL+ L  +L+  ++    + ++     N
Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896

Query: 1868 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
                + ++LQ +L +  EE  ++A  +    R K
Sbjct: 1897 TNLAKFRKLQHELEEA-EERADIAESQVNKLRVK 1929



 Score =  103 bits (257), Expect = 2e-21
 Identities = 124/598 (20%), Positives = 260/598 (43%), Gaps = 78/598 (13%)

Query: 1256 IRNKDEEIQQLRSKLEKA-EKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314
            +R + EE Q+ +++L++A  K   E+     + E+   + T EL + +   +  +Q L A
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK---KKLAQRLQA 1405

Query: 1315 ETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLK 1374
                      +   L+     L+ ++E + ++V       AA    + + D    EW+ K
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465

Query: 1375 YERAVREVDFTKKRLQ-------------QEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
             E    E++ ++K  +             +E  D+LE  ++  + L++ + DL     E 
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525

Query: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
             + + +L+K  +++  E  + +  LE  +      E K  R   EL+Q   E  R+  ++
Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1585

Query: 1482 EKLQREKDMLLAEAFSLKQQLEEK-DMDIAGFTQKV---VSLEAELQDISSQESKDEASL 1537
            ++   E D L      + + ++   D +I      +     +E +L ++  Q +      
Sbjct: 1586 DE---EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642

Query: 1538 AKVKKQLRDLEAKVKDQEEELDEQAGT-------IQMLEQAKLRLEMEMERMRQTHSKEM 1590
            A+  +  R+ +  +KD +  LD+   +       + M+E+    L+ E+E +R T  +  
Sbjct: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1702

Query: 1591 ESR---DEEVEEARQSCQ-------------KKLKQMEVQLEEEYEDKQKVLREKRELEG 1634
             SR   ++E+ +A +  Q             KKL+    Q++ E ED   +L+E R  E 
Sbjct: 1703 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMED---ILQEARNAEE 1759

Query: 1635 KL-------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLMLDHLKNSAPS---- 1681
            K        A +++++ +    S   +R++K++++T   + D QL LD  +  A      
Sbjct: 1760 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---VKDLQLRLDEAEQLALKGGKK 1816

Query: 1682 -----KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSR 1736
                 +  + +L+ ++E  +   A AVK  +  E  +++L  Q ++  K    L++ + +
Sbjct: 1817 QIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDK 1876

Query: 1737 LQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QINDLQAQLEEAN 1787
            LQ +    + + EE +E  N  + K     H+   A+   D+A  Q+N L+ +  E +
Sbjct: 1877 LQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVH 1934



 Score = 81.6 bits (200), Expect = 7e-15
 Identities = 68/301 (22%), Positives = 146/301 (48%), Gaps = 11/301 (3%)

Query: 1257 RNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAET 1316
            RN    ++  +  L+ A + + +L+     +E R + L +E+ + R T E   +      
Sbjct: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709

Query: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLKY 1375
             E L A + ++ L TQ  +L    + +E ++        +++ GE++D          K 
Sbjct: 1710 QELLDASERVQLLHTQNTSLINTKKKLETDI--------SQMQGEMEDILQEARNAEEKA 1761

Query: 1376 ERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQR 1434
            ++A+ +     + L++E +    +E+  K+ +E+ + DLQ   +E+++ AL+  KK+ Q+
Sbjct: 1762 KKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820

Query: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494
            L A +++ +  +E +Q RN E  K  R+ +  + +   + + ++    +LQ   D L A+
Sbjct: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880

Query: 1495 AFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ 1554
              S K+Q EE +        K   L+ EL++   +    E+ + K++ + R++  KV  +
Sbjct: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISE 1940

Query: 1555 E 1555
            E
Sbjct: 1941 E 1941



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 68/267 (25%), Positives = 124/267 (46%), Gaps = 44/267 (16%)

Query: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286
            ++ + E +      EI++LR+ LE+ E+ R     EL   S+R                 
Sbjct: 1676 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735

Query: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340
            LE+ IS++  E+ D     RN  E A + +   A  AE L+ E   ++     + +KK M
Sbjct: 1736 LETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNM 1792

Query: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399
            E   ++ ++ RL  A ++  +      GG+ ++ K E  VRE++      + E E K   
Sbjct: 1793 E-QTVKDLQLRLDEAEQLALK------GGKKQIQKLEARVRELEG-----EVESEQKRNA 1840

Query: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458
            E  +  R+ ERR+ +L   +EE ++ + +L+    +L A+++  K   E  + +++    
Sbjct: 1841 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLA 1900

Query: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485
            K R+   EL +A E A   + Q  KL+
Sbjct: 1901 KFRKLQHELEEAEERADIAESQVNKLR 1927



 Score = 34.7 bits (78), Expect = 0.98
 Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 6/143 (4%)

Query: 1210 KRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRS- 1268
            ++ ++DL +R  +      KG K     KL   VR L E ++  EQ RN  E ++ LR  
Sbjct: 1793 EQTVKDLQLRLDEAEQLALKGGKK-QIQKLEARVREL-EGEVESEQKRNA-EAVKGLRKH 1849

Query: 1269 --KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEM 1326
              ++++   +  E R N  RL+  + +L +++   +   E A +  +   A+  + + E+
Sbjct: 1850 ERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909

Query: 1327 KELQTQYDALKKQMEVMEMEVME 1349
            +E + + D  + Q+  + ++  E
Sbjct: 1910 EEAEERADIAESQVNKLRVKSRE 1932


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score =  506 bits (1302), Expect = e-142
 Identities = 432/1676 (25%), Positives = 787/1676 (46%), Gaps = 206/1676 (12%)

Query: 346  WNETEKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCD 405
            W+  ++VW+       + +++KSE      G+V V+   D  +L V E +++  N P  D
Sbjct: 71   WDGKKRVWVPDEQDAYVEAEVKSEATG---GRVTVETK-DQKVLMVREAELQPMNPPRFD 126

Query: 406  RLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGC 465
             LED+A + +LNE+SVLH LRQRY   +++TY+G   + + P     VY+  V+  +KG 
Sbjct: 127  LLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGK 186

Query: 466  RREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNK 525
            RR D  PHIYAVA  AY  ML +R +QS+++ G SG+GKT + + ++QY A +A +    
Sbjct: 187  RRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDG- 245

Query: 526  VFSVEKWQALYT---------------LLEAFGNSPTIINGNATRFSQILSLDFDQAGQV 570
                +K Q L T                +EAFGN+ T+ N N++RF + + + F  +G++
Sbjct: 246  --PGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKL 303

Query: 571  ASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLN------HLAENNVF 624
            ASA I + LLEK RV  +   E +++V+Y +L+     L+  L L+      H     V 
Sbjct: 304  ASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVI 363

Query: 625  GIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEA 684
             +       +     ++      AM +LG S DE+ AC+ I+ A+ H G     K+    
Sbjct: 364  TV-------DNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNM-KFKQKQRE 415

Query: 685  GRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGP 744
             + +    E A KAAYL+G S  +L   +   +            R G E    G     
Sbjct: 416  EQAEADGTESADKAAYLMGVSSGDLLKGLLHPR-----------VRVGNEYVTKGQSVEQ 464

Query: 745  KLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARG 804
             + A+  L   A   Y  LF  LVS +N+ L +       + ++D  GF+  E       
Sbjct: 465  VVFAVGAL---AKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFN----- 516

Query: 805  ASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQ 864
             SFE+LC N+T ++LQ+ F++  FV E E YK E I+  F D        +  +      
Sbjct: 517  -SFEQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLI------ 569

Query: 865  SLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKP 924
                     ++  G+L +LEEE + P AS+ +   +L+  +  +  + +   P       
Sbjct: 570  ---------EKPLGILSILEEECMFPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQ 620

Query: 925  HHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVL 984
             HF + H  G   V Y++ GWL   K +P  +    + Q SQ ++++ L+   AGS    
Sbjct: 621  AHFEVVHYAGV--VPYSIVGWLEKNK-DPLNETVVPIFQKSQNRLLATLYENYAGSC--- 674

Query: 985  SGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFV 1044
              S    + G +   ++A S +      ++ + K++L        + L+  ++ ++ HFV
Sbjct: 675  --STEPPKSGVKEKRKKAASFQT-----VSQLHKENL--------NKLMTNLRATQPHFV 719

Query: 1045 HCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDA 1104
             C +P      G                              +D  L+  QLR + +L+ 
Sbjct: 720  RCIVPNENKTPG-----------------------------VMDAFLVLHQLRCNGVLEG 750

Query: 1105 MRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCC 1164
            +R+ RQG+P+ +++++FR+R+ +L P        +   +D R+A E+LL  LDL+ +   
Sbjct: 751  IRICRQGFPNRLLYTDFRQRYRILNPSAIP----DDTFMDSRKATEKLLGSLDLDHTQYQ 806

Query: 1165 MGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKN 1224
             G ++VFF+AG L  LEE RD++ ++ LTL QA  RG L R  +++      A+  +Q N
Sbjct: 807  FGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWN 866

Query: 1225 IKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNS 1284
            I+    VK+W W KLF  ++PL+    +EE++     E++ LR  L  AE +R EL    
Sbjct: 867  IRAFNAVKNWSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETH 926

Query: 1285 DRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVME 1344
              +    ++L  +L  E++    A +        +++ E ++KEL    + L+ + EV  
Sbjct: 927  VSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELS---ERLEDEEEVNA 983

Query: 1345 MEVMEARLI--RAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ- 1401
                  R +     E+  ++DD       +L   +A +E   T+ +++   E+   +++ 
Sbjct: 984  DLAARRRKLEDECTELKKDIDD------LKLTLAKAEKEKQATENKVKNLTEEMAALDES 1037

Query: 1402 -----QNKRQL----ERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVR 1452
                 + K+ L    ++ LGDLQA+ +     +  L K   RL  +++D +  LE ++  
Sbjct: 1038 VARLTKEKKALQEAHQQALGDLQAEEDR----VSALTKAKLRLEQQVEDLECSLEQEKKL 1093

Query: 1453 NHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDI 1509
              + E+ +R+ + +L    E   +A ++K Q E+  ++KD   +E   L  ++E++ +  
Sbjct: 1094 RMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKD---SELSQLSLRVEDEQLLG 1150

Query: 1510 AGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTI---- 1565
            A   +K+  L+A  +++  +   + A+ A+V+KQ  +   ++++  E L+E  G      
Sbjct: 1151 AQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQR 1210

Query: 1566 --------------QMLEQAKLRLEMEMERMRQTHSK---EMESRDEEVEEARQSCQKKL 1608
                          + LE+A LR E  +  +R+  ++   E+  + + ++  RQ  +K+ 
Sbjct: 1211 EGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEK 1270

Query: 1609 KQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADA 1668
             ++ +++++   + + + R K   E    T  DQ++    + E+  R+        LADA
Sbjct: 1271 SELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQ--------LADA 1322

Query: 1669 QLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKT 1728
                  L+       E  +L   LEE E   +   + +      +E+L  Q+++ +KAK+
Sbjct: 1323 STQRGRLQT------ESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKS 1376

Query: 1729 ALEEQLSRLQREKNEIQNRLEED---QEDMNELMKKHKAAVAQASRDLAQINDLQAQLEE 1785
            AL   +  L+ + + ++ + EE+   Q ++  L+ K  A VAQ  R   + + +Q + EE
Sbjct: 1377 ALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQ-WRSKYEADAIQ-RTEE 1434

Query: 1786 ANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLA 1845
              + K++L  +LQ  +  VE       +    S ++AK+R L+T  E    +++R  S A
Sbjct: 1435 LEEAKKKLALRLQEAEEGVE-----AANAKCSSLEKAKLR-LQTESEDVTLELERATSAA 1488

Query: 1846 SRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELE 1905
            + L +    L    ++R   E   + + +  QR+ R    E+  L     EA      L+
Sbjct: 1489 AALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLK 1548

Query: 1906 MDLESLEAANQSLQADLKLAFKRIGDLQ---AAIEDEMESDENEDLINSEGDSDVD 1958
             + ++L+     L   + L+ K I +L+    A+E E +S+    L  +EG  +++
Sbjct: 1549 RENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGE-KSEIQAALEEAEGALELE 1603



 Score =  181 bits (460), Expect = 5e-45
 Identities = 185/814 (22%), Positives = 366/814 (44%), Gaps = 72/814 (8%)

Query: 1147 RAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQ 1206
            R +EEL E L+    +          R   L RL  + +E   R+     A  R      
Sbjct: 1190 RELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGA 1249

Query: 1207 HFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQI-RNKDEEIQQ 1265
                 ++  L  + V++ ++K K         L   V  L   + S E++ R  ++++ +
Sbjct: 1250 AELGEQVDSL--QRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSE 1307

Query: 1266 LRSKLEKAEKERNELRLNSDRLESRISELTSELTDERN---TGESASQLLDAETAERLRA 1322
             + K+E+ +++  +      RL++   EL S L +E+    +  S  + L A++ E LR 
Sbjct: 1308 AKIKVEELQRQLADASTQRGRLQTESGEL-SRLLEEKECLISQLSRGKALAAQSLEELRR 1366

Query: 1323 EKE------------MKELQTQYDALKKQMEVMEMEVMEARLIRA-AEINGEVDDDDAGG 1369
            + E            ++ L+   D L++Q E  E    +A L R  ++ N EV       
Sbjct: 1367 QLEEESKAKSALAHAVQALRHDCDLLREQHE--EEAEAQAELQRLLSKANAEV------A 1418

Query: 1370 EWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLK 1429
            +WR KYE    +              + E  ++ K++L  RL + +   E +      L+
Sbjct: 1419 QWRSKYEADAIQ--------------RTEELEEAKKKLALRLQEAEEGVEAANAKCSSLE 1464

Query: 1430 KKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKD 1489
            K   RL  E +D  L LE        L+KKQR  +  L +   + +  + + E  QRE  
Sbjct: 1465 KAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESR 1524

Query: 1490 MLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEA 1549
             L  E F L+   EE    +    ++  +L+ E+ D++ Q S    S+ +++K  + LE 
Sbjct: 1525 GLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEG 1584

Query: 1550 KVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLK 1609
            +  + +  L+E  G +++ E   LR+++E+ +++    +++  +DEE    R++ Q+ ++
Sbjct: 1585 EKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVE 1644

Query: 1610 QMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESE---KRLRKDLKRTKA 1663
             ++  L+ E   + + LR K+++EG L  L  Q+    R+  E++   + ++  LK  +A
Sbjct: 1645 SLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQA 1704

Query: 1664 LLADAQLMLDHLKNSAPS-KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDD 1722
               + Q +   L   A + +R  + L  +LEE         ++R+  E E+ +   +++ 
Sbjct: 1705 GRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNL 1764

Query: 1723 IAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---SRDLAQINDL 1779
            +    T L  Q  +L+ +  ++   +EE  ++  E  +K K A+  A   + +L +  D 
Sbjct: 1765 LHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDT 1824

Query: 1780 QAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFE--- 1834
             A LE   + K+ L++ ++ LQ+++E  EQ+ +   K  V + EAK+RELE  L+ E   
Sbjct: 1825 SAHLE---RMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKK 1881

Query: 1835 --------RTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEE 1886
                    R   +R++ LA + +E+ + L   +D      ++ + + K  +RQ  + +++
Sbjct: 1882 HAEALKGVRKHERRVKELAYQAEEDRKNLARMQD----LVDKLQSKVKSYKRQFEEAEQQ 1937

Query: 1887 MGELARKEAEASRKKHELEMDLESLEAANQSLQA 1920
                  K  +A  +  + E   +  E     L+A
Sbjct: 1938 ANTNLAKYRKAQHELDDAEERADMAETQANKLRA 1971



 Score =  146 bits (368), Expect = 2e-34
 Identities = 207/894 (23%), Positives = 381/894 (42%), Gaps = 136/894 (15%)

Query: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307
            +++L++E + +  ++ QQL  KL+K + E ++L L  +  +   +++  ++ + +   E 
Sbjct: 1107 DLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEE 1166

Query: 1308 ASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDA 1367
              + L+AE A R R EK+  E   + + L +++E                        +A
Sbjct: 1167 LEEELEAERAARARVEKQRAEAARELEELSERLE------------------------EA 1202

Query: 1368 GGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES----QR 1423
            GG    + E   R+ +    RL++E E+     +     L R+  +  A+  E     QR
Sbjct: 1203 GGASAGQRE-GCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQR 1261

Query: 1424 ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREK 1483
              Q+L+K+   L  E+ D   ++E         EK  R ++ +LS+A  + +  + Q   
Sbjct: 1262 VRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLAD 1321

Query: 1484 LQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDEASLAKV 1540
               ++  L  E+  L + LEEK+  I+  ++        L+++  Q   ESK +++LA  
Sbjct: 1322 ASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHA 1381

Query: 1541 KKQLR-DLEAKVKDQEEELDEQAGTIQML-----EQAKLRLEMEMERMRQTHSKE----- 1589
             + LR D +   +  EEE + QA   ++L     E A+ R + E + +++T   E     
Sbjct: 1382 VQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKK 1441

Query: 1590 ----MESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVL-----------REKRELEG 1634
                ++  +E VE A   C   L++ +++L+ E ED    L           +++R LE 
Sbjct: 1442 LALRLQEAEEGVEAANAKCSS-LEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLER 1500

Query: 1635 KLATLSDQVN--RRDFESEKR----LRKDLKRTKALLADAQLMLDHLKNSAPS-KREIAQ 1687
             L     Q    +R+ E+ +R    L  +L R +    +A   L+ LK    + + EI+ 
Sbjct: 1501 ALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISD 1560

Query: 1688 LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE----KNE 1743
            L +Q+  S  +     K +KA+E E  ++   +++   A    E +  R+Q E    K E
Sbjct: 1561 LTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAE 1620

Query: 1744 IQNRLEEDQEDMNELMKKHKAAVA--QASRDL----------------AQINDLQAQLEE 1785
            +  +L E  E+   L + H+ AV   QAS D                   +NDL+ QL  
Sbjct: 1621 VDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGH 1680

Query: 1786 ANKEKQELQEKLQALQSQV---------------EFLEQSMVDKSLVSRQEAKIRELETR 1830
            A ++  E Q   + +Q+Q+               E  EQ+   +   S   A++ EL   
Sbjct: 1681 ATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAA 1740

Query: 1831 LEFERTQVKRLESLASR-LKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGE 1889
            LE    Q +R   LA + L E  E+L     Q     N    Q K+L+  L     E+ E
Sbjct: 1741 LE----QGERSRRLAEQELLEATERLNLLHSQNTGLLN----QKKKLEADLAQLSGEVEE 1792

Query: 1890 LA--RKEAEASRKK---------HELEMDLES---LEAANQSLQADLKLAFKRIGDL-QA 1934
             A  R+EAE   KK          EL+ + ++   LE   ++L+  ++    R+ +  QA
Sbjct: 1793 AAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQA 1852

Query: 1935 AIEDEMESDENEDLINSEGDSDVDSELE---DRVDGVKSWLSKNKGPSKAASDDGSLKS- 1990
            A+    +  +  +    E ++++D+E +   + + GV+    + K  +  A +D    + 
Sbjct: 1853 ALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLAR 1912

Query: 1991 -----SSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYLSDSDTEAKLTETNA 2039
                     S  KS      + E     N ++ R +   L D++  A + ET A
Sbjct: 1913 MQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQA 1966



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 77/303 (25%), Positives = 146/303 (48%), Gaps = 23/303 (7%)

Query: 1246 LIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTG 1305
            L++ QL EEQ   +DEE Q+L ++L +           +  LE R S L +EL + R   
Sbjct: 1694 LMQAQLKEEQA-GRDEE-QRLAAELHE----------QAQALERRASLLAAELEELRAAL 1741

Query: 1306 ESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD 1365
            E   +       E L A + +  L +Q   L  Q + +E ++        A+++GEV++ 
Sbjct: 1742 EQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADL--------AQLSGEVEEA 1793

Query: 1366 -DAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES-QR 1423
                 E   K ++A+ +     + L++E +    +E+  K+ LE+ + +LQA  EE+ Q 
Sbjct: 1794 AQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERM-KKTLEQTVRELQARLEEAEQA 1852

Query: 1424 ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREK 1483
            AL+  KK+ Q+L A++++ +  L+ +Q ++ E  K  R+ +  + +   +A+ ++    +
Sbjct: 1853 ALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLAR 1912

Query: 1484 LQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQ 1543
            +Q   D L ++  S K+Q EE +        K    + EL D   +    E    K++ +
Sbjct: 1913 MQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRAR 1972

Query: 1544 LRD 1546
             RD
Sbjct: 1973 TRD 1975


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score =  502 bits (1293), Expect = e-141
 Identities = 434/1724 (25%), Positives = 813/1724 (47%), Gaps = 239/1724 (13%)

Query: 320  WLRSGEGPRRE----PSDAKTEEQIAAEEAWNETEKVWLVHRDGFSLASQLKSEELNLPE 375
            +LR  E  R E    P DAKT   +A  +                   S +KS   +   
Sbjct: 18   YLRKSEKERIEAQNKPFDAKTSVFVAEPKE------------------SYVKSTIQSKEG 59

Query: 376  GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
            GKV VK +  GA L V ED V   N P  D++ED+A + +L+E  VL+ L++RY A +++
Sbjct: 60   GKVTVKTE-GGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIY 118

Query: 436  TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
            TY+G   + + P     VY  +V+  ++G +R++  PHI++++  AY+ ML  R++QSI+
Sbjct: 119  TYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 178

Query: 496  LLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQ--------ALYTLLEAFGNSPT 547
            + G SG+GKT + + ++QY ATIA     K     K Q        +   LLEAFGN+ T
Sbjct: 179  ITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKT 238

Query: 548  IINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDG 607
            + N N++RF + + + F   G++ASA I+T LLEK RV  +  +E ++++FY + +    
Sbjct: 239  VRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITS---- 294

Query: 608  TLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKACWF 664
              + +L    L   N +    +++ E    +     +L A   A+ +LG +P+E+ + + 
Sbjct: 295  NKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYK 354

Query: 665  ILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQ 724
            +  A+ H G     ++  E   +     E A KAAYL   +  +L  A+   + K G   
Sbjct: 355  LTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKAAYLQSLNSADLLKALCYPRVKVG--- 410

Query: 725  RSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCS 784
             +    +G     + +  G           +A  +Y ++F  +V+ +N+ L + Q     
Sbjct: 411  -NEYVTKGQTVQQVYNAVG----------ALAKAVYEKMFLWMVTRINQQLDTKQPRQYF 459

Query: 785  MMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAF 844
            + ++D  GF+  +        S E+LC N+T ++LQ+ F+   FV E E YK+E IE  F
Sbjct: 460  IGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTF 513

Query: 845  DDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSY 904
             D           +D A+   L+      ++  G+  +LEEE + P A++ +   +L+  
Sbjct: 514  IDF---------GMDLAACIELI------EKPLGIFSILEEECMFPKATDTSFKNKLYDQ 558

Query: 905  YGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQ 963
            +  +  +   Q P +   K   HF L H  GT  V+YN+TGWL+  K +P       L Q
Sbjct: 559  HLGKSAN--FQKPKVVKGKAEAHFSLIHYAGT--VDYNITGWLDKNK-DPLNDTVVGLYQ 613

Query: 964  DSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCI 1023
             S  K +++LF            + A  E  S  A + A     +F T  A  ++     
Sbjct: 614  KSAMKTLASLF-----------STYASAEADSS-AKKGAKKKGSSFQTVSALFRE----- 656

Query: 1024 QMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAG 1083
                 ++ L+  ++ +  HFV C +P                    +E   P        
Sbjct: 657  ----NLNKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA------ 686

Query: 1084 LLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVV 1143
               ++  L+  QLR + +L+ +R+ R+G+P  +++ +F++R+ VL      +       +
Sbjct: 687  ---MEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQ----FI 739

Query: 1144 DERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYL 1203
            D ++A E+LL  +D++ +    G ++VFF+AG L  LEE RDE+ ++ +T  QA CRG+L
Sbjct: 740  DSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFL 799

Query: 1204 ARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEI 1263
             R  ++K   +  A+ C+Q N++    VK WPW KLF  ++PL++   +E+++    EE 
Sbjct: 800  MRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 859

Query: 1264 QQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAE 1323
            Q+ + +L K+E +R EL      L    ++L  ++  E ++   A +  +     +++ E
Sbjct: 860  QKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLE 919

Query: 1324 KEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVREV 1382
             ++KE+  +  A +++    E+   + +L    +E+  ++DD +       K E+     
Sbjct: 920  AKIKEVTER--AEEEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKHAT 974

Query: 1383 DFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQRL 1435
            +   K L +E    ++ +    + K+ L    ++ L DLQA+ ++    +  L K   +L
Sbjct: 975  ENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDK----VNILTKAKTKL 1030

Query: 1436 TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEA 1495
              ++ D +  LE ++    +LE+ +R+ + +L  A E     +  +++L  + +    E 
Sbjct: 1031 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEI 1090

Query: 1496 FSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQE 1555
             +L  ++E++        +K+  L+A ++++  +   + AS AK +KQ  DL  ++++  
Sbjct: 1091 SNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEIS 1150

Query: 1556 EELDEQAGTIQM------------------LEQAKLRLEMEMERMRQTHSKEMESRDEEV 1597
            E L+E  G                      LE+A L+ E  +  +R+ H+  M    E++
Sbjct: 1151 ERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQI 1210

Query: 1598 ---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRDFESEK 1652
               +  +Q  +K+  +++++ ++   + + + + K  LE    +L DQV+  +   E ++
Sbjct: 1211 DNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQ 1270

Query: 1653 RLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVE 1712
            RL  DL   +A L                + E  +   QL+E +   +   ++++A   +
Sbjct: 1271 RLINDLTAQRARL----------------QTEAGEYSRQLDEKDALVSQLSRSKQASTQQ 1314

Query: 1713 IEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVAQ- 1768
            IE+L  Q+++  KAK AL   L   + + + ++ + EE+QE   EL   + K  + VAQ 
Sbjct: 1315 IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQW 1374

Query: 1769 -----------------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFL--- 1807
                             A + LAQ + + +  +E  N +   L++  Q LQ++VE L   
Sbjct: 1375 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD 1434

Query: 1808 -------------EQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEK 1854
                         +Q   DK L    E K +  ET+ E E +Q K   SL++ L +    
Sbjct: 1435 VERSNAACAALDKKQRNFDKVL---SEWKQKYEETQAELEASQ-KESRSLSTELFKVKNV 1490

Query: 1855 LTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA 1914
              E  DQ        + +NK LQ+++ D  E++ E  ++  E  + K ++E +   ++AA
Sbjct: 1491 YEESLDQL----ETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAA 1546

Query: 1915 NQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD 1958
             +  +A L+    +I  +Q  + ++++S+ +  +  +E D ++D
Sbjct: 1547 LEEAEASLEHEEGKILRIQLEL-NQVKSEVDRKI--AEKDEEID 1587



 Score =  189 bits (479), Expect = 3e-47
 Identities = 171/709 (24%), Positives = 338/709 (47%), Gaps = 91/709 (12%)

Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDE--------RNT 1304
            E+  R+ ++++ +L++K E+ ++  N+L     RL++   E + +L ++        R+ 
Sbjct: 1249 EKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSK 1308

Query: 1305 GESASQL------LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AE 1357
              S  Q+      L+ ET  +      ++  +   D L++Q E  E +  +A L RA ++
Sbjct: 1309 QASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYE--EEQEGKAELQRALSK 1366

Query: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417
             N EV       +WR KYE    +              + E  ++ K++L +RL + +  
Sbjct: 1367 ANSEV------AQWRTKYETDAIQ--------------RTEELEEAKKKLAQRLQEAEEH 1406

Query: 1418 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQRE 1477
             E        L+K  QRL  E++D  L +E        L+KKQR FD  LS+  ++ +  
Sbjct: 1407 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEET 1466

Query: 1478 KLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDE 1534
            + + E  Q+E   L  E F +K   EE    +    ++  +L+ E+ D++ Q     K  
Sbjct: 1467 QAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQI 1526

Query: 1535 ASLAKVKKQLR----DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEM 1590
              L K+KKQ+     +++A +++ E  L+ + G I       LR+++E+ +++    +++
Sbjct: 1527 HELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKI-------LRIQLELNQVKSEVDRKI 1579

Query: 1591 ESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFES 1650
              +DEE+++ +++  + ++ M+  L+ E   +   LR K+++EG L  +  Q+N  +  +
Sbjct: 1580 AEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLA 1639

Query: 1651 EKRLRKDLKRTKALLADAQLMLDH-LKNSAPSKREIA-------QLKNQLEESEFTCAAA 1702
             + LR + + T+ +L + QL LD  L+     K ++A        L+ ++EE   T    
Sbjct: 1640 AESLR-NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQT 1698

Query: 1703 VKARKAMEVEIED-------LHLQIDDIAKAKTALEEQLSRLQREKNEI--QNRLEE--- 1750
             ++RK  E E+ D       LH Q   +   K  LE  +S+LQ E  E+  ++R  E   
Sbjct: 1699 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKA 1758

Query: 1751 -----DQEDMNELMKKHK---AAVAQASRDLAQ-INDLQAQLEEA--------NKEKQEL 1793
                 D   M E +KK +   A + +  ++L Q + DLQ +L+EA         K+ Q+L
Sbjct: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1818

Query: 1794 QEKLQALQSQVEFLEQSMVDK-SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852
            + +++ L+ +VE  ++   +    + + E +++EL  + E +R  V RL+ L  +L+  +
Sbjct: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878

Query: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
            +    + ++     N    + ++LQ +L +  EE  ++A  +    R K
Sbjct: 1879 KSYKRQAEEAEEQSNANLSKFRKLQHELEEA-EERADIAESQVNKLRVK 1926



 Score = 99.0 bits (245), Expect = 4e-20
 Identities = 124/596 (20%), Positives = 263/596 (44%), Gaps = 74/596 (12%)

Query: 1256 IRNKDEEIQQLRSKLEKA-EKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314
            +R + EE Q+ +++L++A  K  +E+     + E+   + T EL + +   + A +L +A
Sbjct: 1346 LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK--KLAQRLQEA 1403

Query: 1315 ETAERLRA-EKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL 1373
            E  E + A   +   L+     L+ ++E + ++V  +    AA    + + D    EW+ 
Sbjct: 1404 E--EHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQ 1461

Query: 1374 KYERAVREVD-------------FTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEE 1420
            KYE    E++             F  K + +E  D+LE  ++  + L++ + DL     E
Sbjct: 1462 KYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE 1521

Query: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
              + + +L+K  +++  E  + +  LE  +      E K  R   EL+Q   E  R+  +
Sbjct: 1522 GGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1581

Query: 1481 R-EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
            + E++ + K        +++  L+ +        +    +E +L ++  Q +      A+
Sbjct: 1582 KDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAE 1641

Query: 1540 VKKQLRDLEAKVKDQEEELDEQAG-------TIQMLEQAKLRLEMEMERMRQTHSKEMES 1592
              +  R+ +  +K+ +  LD+           + ++E+    L+ E+E +  T  +   S
Sbjct: 1642 SLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERS 1701

Query: 1593 R---DEEVEEARQSCQ-------------KKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1636
            R   ++E+ +A +  Q             KKL+    QL+ E E+   V++E R  E K 
Sbjct: 1702 RKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEE---VIQESRNAEEKA 1758

Query: 1637 -------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLMLDHLKNSAPS------ 1681
                   A +++++ +    S   +R++K+L++T   + D Q  LD  +  A        
Sbjct: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRLDEAEQLALKGGKKQI 1815

Query: 1682 ---KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQ 1738
               +  + +L+ ++E  +   A AVK  +  E  +++L  Q ++  K    L++ + +LQ
Sbjct: 1816 QKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQ 1875

Query: 1739 REKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QINDLQAQLEEAN 1787
             +    + + EE +E  N  + K     H+   A+   D+A  Q+N L+ +  E +
Sbjct: 1876 AKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVH 1931



 Score = 88.2 bits (217), Expect = 7e-17
 Identities = 133/648 (20%), Positives = 277/648 (42%), Gaps = 107/648 (16%)

Query: 1158 LEKSSCCMGLSRVFFRAGTLARLEE---------QRDEQTSRNLTLFQAACRGYLARQHF 1208
            L K++  +   R  +    + R EE         QR ++   ++    A C      +  
Sbjct: 1364 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQR 1423

Query: 1209 KKRKIQDLAI-------RCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261
             + +++DL +        C   + K+    K    WK         E++ S+++ R+   
Sbjct: 1424 LQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQ-KYEETQAELEASQKESRSLST 1482

Query: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321
            E+ ++++  E++  +   LR  +  L+  IS+LT ++       E   Q+ + E  ++ +
Sbjct: 1483 ELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIA------EGGKQIHELEKIKK-Q 1535

Query: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVD-----DDDAGGEWRLKYE 1376
             E+E  E+Q   +  +  +E  E +++  +L    ++  EVD      D+   + +  + 
Sbjct: 1536 VEQEKCEIQAALEEAEASLEHEEGKILRIQL-ELNQVKSEVDRKIAEKDEEIDQLKRNHT 1594

Query: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436
            R V  +  T     +   D L V    K+++E  L +++     + R   +  +  +   
Sbjct: 1595 RVVETMQSTLDAEIRSRNDALRV----KKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650

Query: 1437 AELQDTKLHLE----GQQVRNHELEKKQRRFDSELSQAHEE---AQREKLQREKLQREKD 1489
              L++T+LHL+    GQ+    +L   +RR  + L QA  E   A  E+ +R +   E++
Sbjct: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERR--ANLLQAEIEELWATLEQTERSRKIAEQE 1708

Query: 1490 MLLAEAFSLKQQLEEKDMDIAGFTQK----VVSLEAELQDISSQESKDEASLAKVKKQLR 1545
            +L  +A    Q L  ++  +    +K    V  L++E++++  QES++     K KK + 
Sbjct: 1709 LL--DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVI-QESRNAEE--KAKKAIT 1763

Query: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE-ARQSC 1604
            D         EEL ++  T   LE+ K  LE  +        K+++ R +E E+ A +  
Sbjct: 1764 DAAMMA----EELKKEQDTSAHLERMKKNLEQTV--------KDLQHRLDEAEQLALKGG 1811

Query: 1605 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKAL 1664
            +K+++++E ++              RELEG++    +   +R+ E+ K LRK  +R K L
Sbjct: 1812 KKQIQKLEARV--------------RELEGEV----ENEQKRNAEAVKGLRKHERRVKEL 1853

Query: 1665 LADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIA 1724
                +            ++ + +L++ +++ +    A VK+ K    E E+         
Sbjct: 1854 TYQTE----------EDRKNVLRLQDLVDKLQ----AKVKSYKRQAEEAEE--------- 1890

Query: 1725 KAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRD 1772
                A   +  +LQ E  E + R +  +  +N+L  K +    + S +
Sbjct: 1891 -QSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score =  502 bits (1292), Expect = e-141
 Identities = 430/1673 (25%), Positives = 815/1673 (48%), Gaps = 222/1673 (13%)

Query: 375  EGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLL 434
            +GKV V+ + D   L V  +DV   N P  DR+ED+A L +LNE +VL+ L+ RY + ++
Sbjct: 57   DGKVTVETE-DNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMI 115

Query: 435  HTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSI 494
            +TY+G   + + P     VY+ +V+  ++G +R++  PHI++++  AY+ ML  R++QSI
Sbjct: 116  YTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSI 175

Query: 495  ILLGSSGSGKTTSCQHLVQYLATIAGISG------NKVFSVEKWQALYT--LLEAFGNSP 546
            ++ G SG+GKT + + ++QY ATIA          +K+    + Q +    LLEAFGN+ 
Sbjct: 176  LITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAK 235

Query: 547  TIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGD 606
            T+ N N++RF + + + F   G++ASA I+T LLEK RV  +  +E ++++FY +L+   
Sbjct: 236  TVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILS--- 292

Query: 607  GTLRTELHLNHLAENNVFGIVPLAKPEEKQKA---AQQFSKLQAAMKVLGISPDEQKACW 663
               + EL    L   N +    +++ E    +   A++     +A+ +LG +P+E+   +
Sbjct: 293  -NKKPELIELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLY 351

Query: 664  FILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTL 723
             +  A+ H G     ++  E   +     E A K AYL+G +  +L  A+   + K G  
Sbjct: 352  KLTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKTAYLMGLNSSDLLKALCFPRVKVGN- 409

Query: 724  QRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLC 783
                      E    G        A+  L   +  +Y +LF  +V+ +N+ L +      
Sbjct: 410  ----------EYVTKGQTVDQVHHAVNAL---SKSVYEKLFLWMVTRINQQLDTKLPRQH 456

Query: 784  SMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELA 843
             + ++D  GF+  E        S E+LC N+T ++LQ+ F+   FV E E YK+E IE  
Sbjct: 457  FIGVLDIAGFEIFEYN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 510

Query: 844  FDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFS 903
            F D           +D A+   L+      ++  G+  +LEEE + P A++ +   +L+ 
Sbjct: 511  FIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLYD 555

Query: 904  YY-GPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLL 962
             + G     +K +  ++      HF L H  GT  V+Y+V+GWL   K +P  +    L 
Sbjct: 556  QHLGKSNNFQKPK--VVKGRAEAHFSLIHYAGT--VDYSVSGWLEKNK-DPLNETVVGLY 610

Query: 963  QDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLC 1022
            Q S  +++++L+   A  AT  + S     G  ++A ++ +S +      ++A+ +++L 
Sbjct: 611  QKSSNRLLAHLY---ATFATADADS-----GKKKVAKKKGSSFQT-----VSALFRENL- 656

Query: 1023 IQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEA 1082
                   + L+  ++ +  HFV C +P                    +E   P       
Sbjct: 657  -------NKLMSNLRTTHPHFVRCIIP--------------------NETKTPGA----- 684

Query: 1083 GLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIV 1142
                ++  L+  QLR + +L+ +R+ R+G+P+ +++ +F++R+ VL      +       
Sbjct: 685  ----MEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQ----F 736

Query: 1143 VDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGY 1202
            +D ++A E+LL  +D++ +    G ++VFF+AG L  LEE RD++ ++ +T  QA CRG+
Sbjct: 737  IDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGF 796

Query: 1203 LARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE 1262
            L R  F+K   +  +I C+Q NI+    VK WPW KLF  ++PL++   +E+++    EE
Sbjct: 797  LMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEE 856

Query: 1263 IQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDER----NTGESASQLLDA---- 1314
             Q+ + +L K+E +R EL      L    ++L  ++  E     +  E   QL+ A    
Sbjct: 857  FQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQL 916

Query: 1315 -----ETAERLRAEKEMK-ELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
                 E  ER   E+E+  EL  +   L+ +   ++ ++ +  L  A     +V+ +   
Sbjct: 917  EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA-----KVEKEKHA 971

Query: 1369 GEWRLK-YERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQ 1427
             E ++K     +  +D T  +L +E +   E  QQ        L DLQA+ ++    +  
Sbjct: 972  TENKVKNLTEELSGLDETIAKLTREKKALQEAHQQ-------ALDDLQAEEDK----VNS 1020

Query: 1428 LKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKL 1484
            L K   +L  +++D +  LE ++    +LE+ +R+ + +L  A E   + + +K Q ++ 
Sbjct: 1021 LNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER 1080

Query: 1485 QREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQL 1544
             ++KD    E   L+ ++E++      F +K+  L+A ++++  +   + A+ AK +KQ 
Sbjct: 1081 LKKKDF---EYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQR 1137

Query: 1545 RDLEAKVKDQEEELDEQAGTIQM------------------LEQAKLRLEMEMERMRQTH 1586
             D   ++++  E L+E  G                      LE+A L+ E  +  +R+ H
Sbjct: 1138 SDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKH 1197

Query: 1587 SKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV 1643
            +  +    E++   +  +Q  +K+  + ++++++     + V + K  LE    TL DQ+
Sbjct: 1198 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQL 1257

Query: 1644 NRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAV 1703
            +    ++E     +++R+ + L   +  L         + E  +L  QLEE E   +   
Sbjct: 1258 SEARGKNE-----EIQRSLSELTTQKSRL---------QTEAGELSRQLEEKESIVSQLS 1303

Query: 1704 KARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MK 1760
            ++++A   + E+L  Q+++  KAK AL   L   + + + ++ + EE+QE   EL   + 
Sbjct: 1304 RSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALS 1363

Query: 1761 KHKAAVAQ------------------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQ 1801
            K  + VAQ                  A + LAQ + D + Q+E  N +   L++  Q LQ
Sbjct: 1364 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQ 1423

Query: 1802 SQVEFLEQSMVD----KSLVSRQEAKIRELETRLEFERTQVKRLES-LASRLKENMEKLT 1856
             +VE L   MVD     SL +  + K R  +  L   +T+ +  ++ L + LKE+    T
Sbjct: 1424 GEVEDL---MVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLST 1480

Query: 1857 EERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQ 1916
            E    + A E    +Q + ++R+ ++ ++E+ +L  + AE  +  HELE   + +E    
Sbjct: 1481 ELFKLKNAYE-EALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELE-- 1537

Query: 1917 SLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVK 1969
              +AD++LA +   + +AA+E E        L  ++  S++D ++ ++ + ++
Sbjct: 1538 --KADIQLALE---EAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIE 1585



 Score =  196 bits (497), Expect = 3e-49
 Identities = 174/695 (25%), Positives = 330/695 (47%), Gaps = 52/695 (7%)

Query: 1247 IEVQLSEEQIRNKDEEIQQLRSKL----EKAEKERNELRLNSDRLESRISELTSELTDER 1302
            +E QLSE   R K+EEIQ+  S+L     + + E  EL    +  ES +S+L+       
Sbjct: 1253 LEDQLSEA--RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFT 1310

Query: 1303 NTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AEINGE 1361
               E   + L+ E   +      ++  +   D L++Q E  E +  +A L RA ++ N E
Sbjct: 1311 QQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYE--EEQEGKAELQRALSKANSE 1368

Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
            V       +WR KYE    +              + E  ++ K++L +RL D +   E  
Sbjct: 1369 V------AQWRTKYETDAIQ--------------RTEELEEAKKKLAQRLQDSEEQVEAV 1408

Query: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
                  L+K  QRL  E++D  + +E        L+KKQR FD  L++   + +  + + 
Sbjct: 1409 NAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAEL 1468

Query: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1541
            E   +E   L  E F LK   EE    +    ++  +LE E+ D++ Q +++  ++ +++
Sbjct: 1469 EASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELE 1528

Query: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601
            K  + +E +  D +  L+E    ++  E   LR+++E+ +++    +++  +DEE+E+ +
Sbjct: 1529 KSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLK 1588

Query: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1661
            ++ Q+ ++ M+  L+ E   + + +R K+++EG L  +  Q++  + ++ + L K L+  
Sbjct: 1589 RNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETL-KHLRSV 1647

Query: 1662 KALLADAQLMLDH-LKNSAPSKREIA-------QLKNQLEESEFTCAAAVKARKAMEVEI 1713
            +  L D QL LD  L+     K ++A        L+ ++EE   T     +ARK  E E+
Sbjct: 1648 QGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQEL 1707

Query: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---S 1770
             D + ++  +    T+L     +L+ +  ++Q+ +E+   D     +K K A+  A   +
Sbjct: 1708 LDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMA 1767

Query: 1771 RDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELE 1828
             +L +  D  A LE   + K+ L++ ++ LQ +++  EQ  +   K  + + E +IRELE
Sbjct: 1768 EELKKEQDTSAHLE---RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELE 1824

Query: 1829 TRLEFERTQ----VKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTK 1884
              LE E+ +    VK L     R+KE   +  E+R   +  ++   +   +++   R   
Sbjct: 1825 FELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQA- 1883

Query: 1885 EEMGELARKEAEASRK-KHELEMDLESLEAANQSL 1918
            EE  E A       RK +HELE   E  + A   +
Sbjct: 1884 EEADEQANAHLTKFRKAQHELEEAEERADIAESQV 1918



 Score =  165 bits (418), Expect = 4e-40
 Identities = 194/811 (23%), Positives = 364/811 (44%), Gaps = 102/811 (12%)

Query: 1246 LIEVQLSEEQIR--NK-----DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSEL 1298
            L ++Q  E+++   NK     +++++ L S LE+ +K R +L  N  +LE  +      +
Sbjct: 1008 LDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESI 1067

Query: 1299 TDERNTGESASQLLDAETAERLRAEKEMKELQT-------QYDALKKQMEVMEMEVMEAR 1351
             D  N  +   + L  +  E  + + ++++ QT       +   L+ ++E +E E+   R
Sbjct: 1068 LDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 1127

Query: 1352 LIRA------AEINGEVDD-----DDAGGEWRLKYE-RAVREVDFTKKRLQQEFEDKLEV 1399
              RA      ++   E+++     ++AGG    + E    RE +F K  L+++ E+    
Sbjct: 1128 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLK--LRRDLEEATLQ 1185

Query: 1400 EQQNKRQLERRLGDLQADSEES----QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455
             +     L ++  D  A+  E     QR  Q+L+K+      E+ D    +E        
Sbjct: 1186 HEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKAN 1245

Query: 1456 LEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIA----- 1510
            LEK  R  + +LS+A  + +  +    +L  +K  L  EA  L +QLEEK+  ++     
Sbjct: 1246 LEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRS 1305

Query: 1511 --GFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
               FTQ+   L+ +L++    E+K + +LA   +  R     +++Q EE  EQ G  + L
Sbjct: 1306 KQAFTQQTEELKRQLEE----ENKAKNALAHALQSSRHDCDLLREQYEE--EQEGKAE-L 1358

Query: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
            ++A  +   E+ + R  +  +   R EE+EEA++   ++L+  E Q+E        + + 
Sbjct: 1359 QRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKT 1418

Query: 1629 KRELEGKLATLSDQVNRRDF------ESEKRLRKDLKRTKALLADAQLMLD-HLKNSAPS 1681
            K+ L+G++  L   V R +       + ++   K L   K    ++Q  L+  LK S   
Sbjct: 1419 KQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSL 1478

Query: 1682 KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
              E+ +LKN  EE+        +  K +E EI DL  QI +  K    LE+   +++ EK
Sbjct: 1479 STELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEK 1538

Query: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
             +IQ  LEE                A+A+ +  +   L+ QLE   + K E+  K+    
Sbjct: 1539 ADIQLALEE----------------AEAALEHEEAKILRIQLE-LTQVKSEIDRKIAEKD 1581

Query: 1802 SQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQ 1861
             ++E L+++   +++ + Q A   E+ +R E            A RLK+ ME    E + 
Sbjct: 1582 EEIEQLKRNY-QRTVETMQSALDAEVRSRNE------------AIRLKKKMEGDLNEIEI 1628

Query: 1862 RIAAENREKEQN----KRLQRQLRDTKEEMGELARKE-------AEASRKKHELEMDLES 1910
            +++  NR+  +     + +Q QL+DT+  + +  R +       A   R+ + L+ ++E 
Sbjct: 1629 QLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEE 1688

Query: 1911 LEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD-----SELEDRV 1965
            L A  +  +   KLA + + D    +  ++   +N  LI+++   + D     SE+ED  
Sbjct: 1689 LRATLEQTERARKLAEQELLDSNERV--QLLHTQNTSLIHTKKKLETDLMQLQSEVEDAS 1746

Query: 1966 DGVKSWLSK-NKGPSKAASDDGSLKSSSPTS 1995
               ++   K  K  + AA     LK    TS
Sbjct: 1747 RDARNAEEKAKKAITDAAMMAEELKKEQDTS 1777



 Score = 84.7 bits (208), Expect = 8e-16
 Identities = 79/327 (24%), Positives = 155/327 (47%), Gaps = 29/327 (8%)

Query: 1247 IEVQLSEEQIRNKDEEIQQLRS----------KLEKAEKERNELRLNSDRLESRISELTS 1296
            IE+QLS    R   E ++ LRS           L+ A + + +L+     +E R + L +
Sbjct: 1626 IEIQLSHAN-RQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQA 1684

Query: 1297 ELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAA 1356
            E+ + R T E   +       E L + + ++ L TQ  +L    + +E ++M+       
Sbjct: 1685 EVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQ------- 1737

Query: 1357 EINGEVDD---DDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD 1413
             +  EV+D   D    E + K  +A+ +     + L++E +    +E+  K+ LE+ + D
Sbjct: 1738 -LQSEVEDASRDARNAEEKAK--KAITDAAMMAEELKKEQDTSAHLERM-KKNLEQTVKD 1793

Query: 1414 LQADSEESQR-ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE 1472
            LQ   +E+++ AL+  KK+ Q+L   +++ +  LEG+Q +N E  K  R+++  + +   
Sbjct: 1794 LQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTY 1853

Query: 1473 EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESK 1532
            +++ ++    +LQ   D L  +  S K+Q EE D        K    + EL++   +   
Sbjct: 1854 QSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1913

Query: 1533 DEASLAKVKKQLRDLEAK---VKDQEE 1556
             E+ + K++ + RD  +    V + EE
Sbjct: 1914 AESQVNKLRAKTRDFTSSRMVVHESEE 1940


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score =  501 bits (1290), Expect = e-141
 Identities = 420/1673 (25%), Positives = 789/1673 (47%), Gaps = 192/1673 (11%)

Query: 376  GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
            GKV  K +  GA + V ED V   N P  D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 58   GKVTAKTEA-GATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116

Query: 436  TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
            TY+G   + + P     VY+ +V+  ++G +R++  PHI++++  AY+ ML  R++QSI+
Sbjct: 117  TYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176

Query: 496  LLGSSGSGKTTSCQHLVQYLATIAGISGNKVFS-----------VEKWQALYTLLEAFGN 544
            + G SG+GKT + + ++QY ATIA ++G K               ++  +   LLEAFGN
Sbjct: 177  ITGESGAGKTVNTKRVIQYFATIA-VTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGN 235

Query: 545  SPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLAC 604
            + T+ N N++RF + + + F   G++ASA I+T LLEK RV  +  +E ++++FY +L+ 
Sbjct: 236  AKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILS- 294

Query: 605  GDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKA 661
                 + EL    L   N +    +++ E    +     +L A   A+ +LG + DE+ A
Sbjct: 295  ---NKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVA 351

Query: 662  CWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGG 721
             + +  A+ H G     ++  E   +     E A KAAYL   +  +L  ++   + K G
Sbjct: 352  IYKLTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKAAYLTSLNSADLLKSLCYPRVKVG 410

Query: 722  TLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHS 781
                +    +G     + +  G           +A  +Y ++F  +V+ +N+ L + Q  
Sbjct: 411  ----NEFVTKGQTVQQVYNAVG----------ALAKAIYEKMFLWMVTRINQQLDTKQPR 456

Query: 782  LCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIE 841
               + ++D  GF+  +        S E+LC N+T ++LQ+ F+   FV E E YK+E IE
Sbjct: 457  QYFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510

Query: 842  LAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERL 901
              F D           +D A+   L+      ++  G+  +LEEE + P A++ +   +L
Sbjct: 511  WEFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKL 555

Query: 902  FSYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR 960
            +  +  +  +   Q P     KP  HF L H  GT  V+YN+ GWL+  K +P  +    
Sbjct: 556  YEQHLGKSNN--FQKPKPAKGKPEAHFSLVHYAGT--VDYNIAGWLDKNK-DPLNETVVG 610

Query: 961  LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1020
            L Q S  K ++ LF   +G+ T  +    G +GG +           +F T  A  ++  
Sbjct: 611  LYQKSAMKTLAFLF---SGAQTAEAEGGGGKKGGKKKG--------SSFQTVSALFRE-- 657

Query: 1021 LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC 1080
                    ++ L+  ++ +  HFV C +P                    +E   P     
Sbjct: 658  -------NLNKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA--- 687

Query: 1081 EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY 1140
                  ++  L+  QLR + +L+ +R+ R+G+P  +++++F++R+ VL      +     
Sbjct: 688  ------MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ--- 738

Query: 1141 IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR 1200
              +D ++A E+LL  ++++ +    G ++VFF+AG L  LEE RDE+ ++ +T  QA CR
Sbjct: 739  -FIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICR 797

Query: 1201 GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD 1260
            G+L R  F+K   +  +I C+Q NI+    VK WPW KL+  ++PL++   +E+++ N  
Sbjct: 798  GFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMK 857

Query: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320
            EE ++ + +L K E +R EL      L    ++L  ++  E +    A +  D     ++
Sbjct: 858  EEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKI 917

Query: 1321 RAEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAV 1379
            + E ++KE+  +  A  ++    E+   + +L    +E+  ++DD +       K E+  
Sbjct: 918  QLEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEK 972

Query: 1380 REVDFTKKRLQQE---FEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436
               +   K L +E    ++ +    + K+ L+        D +  +  +  L K   +L 
Sbjct: 973  HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLE 1032

Query: 1437 AELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF 1496
             ++ D +  LE ++    +LE+ +R+ + +L  A E     +  +++L  +      E  
Sbjct: 1033 QQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMS 1092

Query: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEE 1556
            +L+ ++E++        +K+  L+A ++++  +   + AS AK +KQ  DL  ++++  E
Sbjct: 1093 NLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE 1152

Query: 1557 ELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLE 1616
             L+E  G      +   + E E ++MR+   +     +      R+     + ++  Q++
Sbjct: 1153 RLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQID 1212

Query: 1617 EEYEDKQKVLREKRELEGKLATLSDQVN-----RRDFESEKRLRKD-LKRTKALLADAQL 1670
                 KQK+ +EK EL+ ++  L+  +      + +FE   R  +D L   K    + Q 
Sbjct: 1213 SLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQR 1272

Query: 1671 MLDHLK-NSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTA 1729
            +++ L    A    E  +   QL+E +   +   + ++A   +IE+L  Q+++  KAK+ 
Sbjct: 1273 LINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKST 1332

Query: 1730 LEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVAQ------------------ 1768
            L   L   + + + ++ + EE+QE   EL   M K  + VAQ                  
Sbjct: 1333 LAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE 1392

Query: 1769 ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFL----------------EQSM 1811
            A + LAQ + D +  +E  N +   L++  Q LQ++VE L                +Q  
Sbjct: 1393 AKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRN 1452

Query: 1812 VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871
             DK L    E K +  ET+ E E +Q K   SL++ L +      E  D         K 
Sbjct: 1453 FDKVLA---EWKQKYEETQAELEASQ-KESRSLSTELFKVKNAYEESLDHL----ETLKR 1504

Query: 1872 QNKRLQRQLRDTKEEMG-------ELARKEAEASRKKHELEMDLESLEAANQSLQADLKL 1924
            +NK LQ+++ D  E++        EL + + +   +K EL+  LE  EA+ +  +  +  
Sbjct: 1505 ENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILR 1564

Query: 1925 AFKRIGDLQAAIEDEM-ESDENEDLIN-------SEGDSDVDSELEDRVDGVK 1969
                +  +++ I+ ++ E DE  D +            S +D+E+  R D ++
Sbjct: 1565 IQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALR 1617



 Score =  192 bits (487), Expect = 4e-48
 Identities = 153/687 (22%), Positives = 333/687 (48%), Gaps = 47/687 (6%)

Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
            E+  R  ++++ ++++K E+ ++  NEL     RL +   E + +L DE++     SQL 
Sbjct: 1250 EKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQL-DEKDA--MVSQLS 1306

Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
              + A   + E+  ++L+ +  A       ++    +  L+R        ++ +A  E +
Sbjct: 1307 RGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQY----EEEQEAKAELQ 1362

Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
                +A  EV   + + + +   + E  ++ K++L +RL D +   E        L+K  
Sbjct: 1363 RGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTK 1422

Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492
            QRL  E++D  + +E        L+KKQR FD  L++  ++ +  + + E  Q+E   L 
Sbjct: 1423 QRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLS 1482

Query: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVK 1552
             E F +K   EE    +    ++  +L+ E+ D++ Q ++    + +++K  + L+ +  
Sbjct: 1483 TELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKS 1542

Query: 1553 DQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME 1612
            + +  L+E   +++  E   LR+++E+ +++    +++  +DEE+++ +++  + ++ M+
Sbjct: 1543 ELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQ 1602

Query: 1613 VQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML 1672
              L+ E   +   LR K+++EG L  +  Q+N  + ++ + LR +L+ T+ +L D QL L
Sbjct: 1603 STLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALR-NLRNTQGILKDTQLHL 1661

Query: 1673 DH-LKNSAPSKREIAQLKN-------QLEESEFTCAAAVKARKAMEVEIED-------LH 1717
            D  ++     K ++A ++        ++EE   +     + RK  E E+ D       LH
Sbjct: 1662 DDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLH 1721

Query: 1718 LQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMKKHK---A 1764
             Q   +   K  LE  +S++Q E  +I       +E           M E +KK +   A
Sbjct: 1722 TQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781

Query: 1765 AVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLEQSMVDK- 1814
             + +  +++ Q + DLQ +L+EA         K+ Q+L+ +++ L+S+VE  ++  V+  
Sbjct: 1782 HLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAV 1841

Query: 1815 SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNK 1874
              + + E +++EL  + E +R  + RL+ L  +L+  ++    + ++     N    + +
Sbjct: 1842 KGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFR 1901

Query: 1875 RLQRQLRDTKEEMGELARKEAEASRKK 1901
            +LQ +L + KE   ++A  +    R K
Sbjct: 1902 KLQHELEEAKER-ADIAESQVNKLRVK 1927



 Score = 74.7 bits (182), Expect = 9e-13
 Identities = 64/302 (21%), Positives = 146/302 (48%), Gaps = 11/302 (3%)

Query: 1256 IRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAE 1315
            +RN    ++  +  L+ A + +++L+     +E R + + +E+ + R + E   +     
Sbjct: 1647 LRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMA 1706

Query: 1316 TAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLK 1374
              E L A + ++ L TQ  +L    + +E ++        ++I GE++D          K
Sbjct: 1707 EQELLDASERVQLLHTQNTSLINTKKKLETDI--------SQIQGEMEDIVQEARNAEEK 1758

Query: 1375 YERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQ 1433
             ++A+ +     + L++E +    +E+  K+ +E+ + DLQ   +E+++ AL+  KK+ Q
Sbjct: 1759 AKKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQ 1817

Query: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
            +L A +++ +  +E +Q  N E  K  R+ +  + +   + + ++    +LQ   D L  
Sbjct: 1818 KLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQT 1877

Query: 1494 EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKD 1553
            +  + K+Q EE +        K   L+ EL++   +    E+ + K++ + R++  KV  
Sbjct: 1878 KVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTKVIS 1937

Query: 1554 QE 1555
            +E
Sbjct: 1938 EE 1939



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 67/267 (25%), Positives = 124/267 (46%), Gaps = 44/267 (16%)

Query: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286
            ++ + E +      E+++LR+ LE+ E+ R     EL   S+R                 
Sbjct: 1674 QLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKK 1733

Query: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340
            LE+ IS++  E+ D     RN  E A + +   A  AE L+ E   ++     + +KK M
Sbjct: 1734 LETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNM 1790

Query: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399
            E   ++ ++ RL  A ++  +      GG+ ++ K E  VRE++      + E E K  V
Sbjct: 1791 E-QTVKDLQLRLDEAEQLALK------GGKKQIQKLEARVRELE-----SEVESEQKHNV 1838

Query: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458
            E  +  R+ ERR+ +L   +EE ++ + +L+    +L  +++  K   E  + +++    
Sbjct: 1839 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLA 1898

Query: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485
            K R+   EL +A E A   + Q  KL+
Sbjct: 1899 KFRKLQHELEEAKERADIAESQVNKLR 1925



 Score = 32.7 bits (73), Expect = 3.7
 Identities = 57/280 (20%), Positives = 118/280 (42%), Gaps = 43/280 (15%)

Query: 1082 AGLLQLDVPLLRTQL----RGSR-----LLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHL 1132
            A L+Q +V  LR  L    RG +     LLDA    +  +  +      +++ +     +
Sbjct: 1682 ANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLET---DI 1738

Query: 1133 TKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNL 1192
            ++  G    +V E R  EE  +    + +     L +    +  L R+++   EQT ++L
Sbjct: 1739 SQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM-EQTVKDL 1797

Query: 1193 TLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS 1252
             L              +  + + LA++  +K I+K           L   VR L E ++ 
Sbjct: 1798 QL--------------RLDEAEQLALKGGKKQIQK-----------LEARVREL-ESEVE 1831

Query: 1253 EEQIRNKDEEIQQLRS---KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESAS 1309
             EQ  N  E ++ LR    ++++   +  E R N  RL+  + +L +++   +   E A 
Sbjct: 1832 SEQKHNV-EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAE 1890

Query: 1310 QLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
            +  +   A+  + + E++E + + D  + Q+  + ++  E
Sbjct: 1891 EQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSRE 1930


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score =  494 bits (1272), Expect = e-139
 Identities = 421/1641 (25%), Positives = 756/1641 (46%), Gaps = 190/1641 (11%)

Query: 350  EKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLED 409
            +K W+   +   + +++K  E    +G V V+   DG  L + ED +++ N P  + +ED
Sbjct: 52   KKCWIPDGENAYIEAEVKGSE---DDGTVIVETA-DGESLSIKEDKIQQMNPPEFEMIED 107

Query: 410  LASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRRED 469
            +A L +LNE+SVLHTL++RYG  +++TY+G   + + P     VY ++VM  +KG RR +
Sbjct: 108  MAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSE 167

Query: 470  MAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI--SGNKVF 527
              PHI+AVA  A++ ML +R++QSI+  G SG+GKT + +H++QY ATIA +  S  K  
Sbjct: 168  APPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQG 227

Query: 528  SVE-KWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVA 586
            ++E +     T+LEAFGN+ T+ N N++RF + + + F   G ++S  I   LLEK RV 
Sbjct: 228  ALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVI 287

Query: 587  RRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNV--FGIVPL-AKPEEKQKAAQQFS 643
             + A E  +++FY +L+      + ELH   L   N   F      A   E    A++  
Sbjct: 288  FQQAGERNYHIFYQILSG-----QKELHDLLLVSANPSDFHFCSCGAVTVESLDDAEELL 342

Query: 644  KLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLG 703
              + AM +LG  PDE+  C+ +  AI H G     ++  E  + +    E A KAA+L+G
Sbjct: 343  ATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREE-QLEADGTENADKAAFLMG 401

Query: 704  CSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEG-MAAGLYSE 762
             +  EL   +   + K G    +                G  +  + C  G ++  +Y  
Sbjct: 402  INSSELVKCLIHPRIKVGNEYVTR---------------GQTIEQVTCAVGALSKSMYER 446

Query: 763  LFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRL 822
            +F  LV+ +NRAL +       + I+D  GF+  E        S E+LC N+T ++LQ+ 
Sbjct: 447  MFKWLVARINRALDAKLSRQFFIGILDITGFEILEYN------SLEQLCINFTNEKLQQF 500

Query: 823  FHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWL 882
            F+   FV E E YK+E+IE                V       L   +   ++  G+L +
Sbjct: 501  FNWHMFVLEQEEYKKESIEW---------------VSIGFGLDLQACIDLIEKPMGILSI 545

Query: 883  LEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPH------HFLLGHSHGTN 936
            LEEE + P A++ T   +LF  +        G+S  L   KP       HF L H  G  
Sbjct: 546  LEEECMFPKATDLTFKTKLFDNHF-------GKSVHLQKPKPDKKKFEAHFELVHYAGV- 597

Query: 937  WVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQ 996
             V YN++GWL   K +   +    + Q S  +++++LF     + + +       + G+ 
Sbjct: 598  -VPYNISGWLEKNK-DLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGA- 654

Query: 997  LALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAG 1056
                       +F T +A++ K++L        + L+  +K +  HFV C  P      G
Sbjct: 655  -----------SFQT-VASLHKENL--------NKLMTNLKSTAPHFVRCINPNVNKIPG 694

Query: 1057 EPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHM 1116
                                          LD  L+  QLR + +L+  R+ R+G+P+ +
Sbjct: 695  I-----------------------------LDPYLVLQQLRCNGVLEGTRICREGFPNRL 725

Query: 1117 VFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGT 1176
             +++F++R+ +L P    K       V  R+A EELL  L+++ +    G+++VFF+AG 
Sbjct: 726  QYADFKQRYCILNPRTFPKSK----FVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGF 781

Query: 1177 LARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPW 1236
            L +LE  RDE+ S+  TLFQA  +G L R  F+K   +  A+  +Q NI+    VK+WPW
Sbjct: 782  LGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPW 841

Query: 1237 WKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTS 1296
             +LF  ++PL++     E++    EE  QL+  LEK+E +R EL+     L    ++L  
Sbjct: 842  MRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLIL 901

Query: 1297 ELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAA 1356
            +L  E+ T  +  +  +     +++ E  +KEL                     R+    
Sbjct: 902  QLQAEQETLANVEEQCEWLIKSKIQLEARVKEL-------------------SERVEEEE 942

Query: 1357 EINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQA 1416
            EIN E+    A G       R + +  F  K+   + E  L   ++ KR  E ++ +L  
Sbjct: 943  EINSEL---TARG-------RKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTE 992

Query: 1417 DSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476
            + E     + +L +  + +    Q T   L  ++ +   L K   + + ++ +     ++
Sbjct: 993  EVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQ 1052

Query: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS 1536
            E+  R   +RE   L       ++ +E  +       +++   E EL  ++S+   ++  
Sbjct: 1053 ERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGL 1112

Query: 1537 LAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEE 1596
            +A+++K +++L+ ++KD +E+L+ +  T             +MER R   ++++   +E 
Sbjct: 1113 VAQLQKTVKELQTQIKDLKEKLEAERTT-----------RAKMERERADLTQDLADLNER 1161

Query: 1597 VEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRK 1656
            +EE   S    L Q+E+  ++E +  QK+ R+  E      T S  + +R  +S   L  
Sbjct: 1162 LEEVGGS---SLAQLEITKKQETK-FQKLHRDMEEATLHFETTSASLKKRHADSLAELEG 1217

Query: 1657 DLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1716
             ++  + +    +      K+ +  + E+  L  ++E+     A A K     E  + + 
Sbjct: 1218 QVENLQQVKQKLE------KDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEA 1271

Query: 1717 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1776
              ++D + +    L  Q ++L  E  E   RLEE +  +N+L +       + S    QI
Sbjct: 1272 TAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSR-------EKSNFTRQI 1324

Query: 1777 NDLQAQLEEANKEKQELQEKLQALQSQVEFL----EQSMVDKSLVSRQEAKIRE--LETR 1830
             DL+ QLE+  K +  L   LQ  Q   + L    E+    K+ + R  +K+    ++ R
Sbjct: 1325 EDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWR 1384

Query: 1831 LEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENRE---KEQNKRLQRQLRDTKEEM 1887
            +++E   ++R E L    KE   +L E  +    A  R    +    +LQ +L D   ++
Sbjct: 1385 MKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDL 1444

Query: 1888 GELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENED 1947
            G++    A   +K+ +    L   +  ++  QA L  + K +  L   +  ++++   E 
Sbjct: 1445 GKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELL-KLKNTYEES 1503

Query: 1948 LINSEGDSDVDSELEDRVDGV 1968
            ++  E     +  L++ +  +
Sbjct: 1504 IVGQETLRRENKNLQEEISNL 1524



 Score =  154 bits (389), Expect = 8e-37
 Identities = 174/803 (21%), Positives = 363/803 (45%), Gaps = 79/803 (9%)

Query: 1176 TLARLEEQRDEQTS---RNLTLFQAACRGYLARQHFKKRKIQDLA--------IRCVQKN 1224
            +LA+LE  + ++T     +  + +A           KKR    LA        ++ V++ 
Sbjct: 1169 SLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQK 1228

Query: 1225 IKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE-IQQLRSKLEKAEKERNELRLN 1283
            ++K+K         L T V  +   + + E++    EE + +  +KL+K  +  N+L   
Sbjct: 1229 LEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQ 1288

Query: 1284 SDRL--------------ESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKEL 1329
              +L              E+ I++L+ E ++     E     L+ ET  +      +++ 
Sbjct: 1289 KTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKA 1348

Query: 1330 QTQYDALKKQMEVMEMEVMEARLIRA-AEINGEVDDDDAGGEWRLKYERAV----REVDF 1384
            Q   D L++Q E  E + ++A L R  +++N E+       +WR+KYE  V     +++ 
Sbjct: 1349 QRDCDLLREQYE--EEQEVKAELHRTLSKVNAEMV------QWRMKYENNVIQRTEDLED 1400

Query: 1385 TKKRLQ---QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQD 1441
             KK L    QE  + + V       LER    LQ +  ++   L +++    RL     D
Sbjct: 1401 AKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARL-----D 1455

Query: 1442 TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQ 1501
             K    G+ +             ++  Q HEE+Q      +  Q+E   L  E   LK  
Sbjct: 1456 QKQLQSGKAL-------------ADWKQKHEESQA---LLDASQKEVQALSTELLKLKNT 1499

Query: 1502 LEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQ 1561
             EE  +      ++  +L+ E+ ++++Q  +   +L +++K  + +E +  + +  L+E 
Sbjct: 1500 YEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEET 1559

Query: 1562 AGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYED 1621
             G ++  E   L  ++E+   +    +++  +DEE+E  R+  Q  +  ++  L+ E + 
Sbjct: 1560 EGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKS 1619

Query: 1622 KQKVLREKRELEGKLATLSDQV---NRRDFESEK---RLRKDLKRTKALLADA-QLMLDH 1674
            + +V R K+++E  L  +  Q+   NR+  E+ K   +L+  +K  +  L D+ QL  D 
Sbjct: 1620 RIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDL 1679

Query: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734
             +  A ++R  + L+++LE+         + R+  E E+ +   +I+      T+L  Q 
Sbjct: 1680 KEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQK 1739

Query: 1735 SRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQ 1794
             +L+ +   +Q   EE  ++     +K K A  +A+    ++   Q  +    + ++ ++
Sbjct: 1740 KKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENME 1799

Query: 1795 EKLQALQSQVEFLEQS--MVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852
            + +  LQ ++   EQ   M  +  + + E+++RELE  LE E  +    +  A RL+  +
Sbjct: 1800 QTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCI 1859

Query: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEA-----EASRKKHELEMD 1907
            ++LT + ++     +R + Q  +LQ ++++ K+++ E+A  +A     +  +++HEL   
Sbjct: 1860 KELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQV-EVAETQANQYLSKYKKQQHELNEV 1918

Query: 1908 LESLEAANQSLQADLKLAFKRIG 1930
             E  E A   +   LK+  +  G
Sbjct: 1919 KERAEVAESQVN-KLKIKAREFG 1940



 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 78/318 (24%), Positives = 156/318 (49%), Gaps = 18/318 (5%)

Query: 1247 IEVQLS--EEQIRNKDEEIQQLRSKLEKAEKERNE-LRLNSDRLES------RISELTSE 1297
            +E+QLS    Q+    + + QL+ +++  + + ++  +LNSD  E       R S L SE
Sbjct: 1637 MELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSE 1696

Query: 1298 LTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 1357
            L D R+  E   +       E L A + +    TQ  +L  Q + +E +V  AR+ + AE
Sbjct: 1697 LEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADV--ARMQKEAE 1754

Query: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417
               EV  +    E + K  +A  E     + L+++ +D +   ++ +  +E+ + DLQ  
Sbjct: 1755 ---EVVQECQNAEEKAK--KAAIEAANLSEELKKK-QDTIAHLERTRENMEQTITDLQKR 1808

Query: 1418 -SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476
             +E  Q AL   +K+ Q+L + +++ +  LEG+  R+ E ++  RR +  + +   +A+ 
Sbjct: 1809 LAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEE 1868

Query: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS 1536
            +K    ++Q + D L  +  + KQQ+E  +     +  K    + EL ++  +    E+ 
Sbjct: 1869 DKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQ 1928

Query: 1537 LAKVKKQLRDLEAKVKDQ 1554
            + K+K + R+   KV+++
Sbjct: 1929 VNKLKIKAREFGKKVQEE 1946


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  302 bits (773), Expect = 3e-81
 Identities = 344/1470 (23%), Positives = 654/1470 (44%), Gaps = 197/1470 (13%)

Query: 340  IAAEEAWNETEKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKA 399
            +A  E + +  +VW+   +    ++++ +++  + +  +R+ L+ DG  LD   +     
Sbjct: 1    MAVAELYTQYNRVWIPDPEEVWKSAEI-AKDYRVGDKVLRLLLE-DGTELDYSVNPESLP 58

Query: 400  NAPSCDRL---EDLASLVYLNESSVLHTLRQRYGAS-LLHTYAGPSLLVLGPRGAPAVYS 455
               + D L    DL +L YL+E +VLH LR R+  S L++TY+G  L+ + P     +Y 
Sbjct: 59   PLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYG 118

Query: 456  EKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYL 515
            + ++H + G    DM PHI+AVA+ AY+ M  + ++QSII+ G SG+GKT S ++ ++Y 
Sbjct: 119  DAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYF 178

Query: 516  ATIAGISGNKVFSVEKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASI 575
            AT++  SG+     +K  A   + EA GN+ T  N N++RF +   + FD+  Q+  A++
Sbjct: 179  ATVSK-SGSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANM 237

Query: 576  QTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEK 635
             T LLEK RV  +  +E  +++FY L A    +    L L    E N   +      E  
Sbjct: 238  STYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGV 297

Query: 636  QKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWA 695
               A+   + Q    +LG   D Q   + ILAAI HLG    T    E       R   +
Sbjct: 298  NDRAEMV-ETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNE-------RSSVS 349

Query: 696  QKAAYL-LGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEG 754
            +  ++L + C L  L S           +  S+       E+ +   T P+  A+   + 
Sbjct: 350  EDDSHLKVFCELLGLESGRVAQWLCNRKIVTSS-------ETVVKPMTRPQ--AVNARDA 400

Query: 755  MAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNY 814
            +A  +Y+ LF  +V  +N+AL+ S      + ++D  GF+  +        SFE+ C NY
Sbjct: 401  LAKKIYAHLFDFIVERINQALQFSGKQHTFIGVLDIYGFETFDVN------SFEQFCINY 454

Query: 815  TQDRLQRLFHERTFVQELERYKEENIE---LAFDDLEPPTDDSVAAVDQASHQSLVRSLA 871
              ++LQ+ F+   F  E E Y +E+I    + F D +P  D                   
Sbjct: 455  ANEKLQQQFNMHVFKLEQEEYMKEDIPWTLIDFYDNQPVID------------------- 495

Query: 872  RTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGH 931
              +   G+L LL+EE L+P  +++  L++L++ +         ++PL    +  +     
Sbjct: 496  LIEAKMGILELLDEECLLPHGTDENWLQKLYNNF-------VNRNPLFEKPRMSNTSFVI 548

Query: 932  SHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGL 991
             H  + VEY   G+L    ++        +L+ S+  + +N F       +   GS+  +
Sbjct: 549  QHFADKVEYKCEGFLE-KNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPF-GSMITV 606

Query: 992  EGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVA 1051
            +   Q+    +    K F T + +  + SL +        L++T+  +  H+V C  P  
Sbjct: 607  KSAKQVIKPNS----KHFRTTVGSKFRSSLYL--------LMETLNATTPHYVRCIKP-- 652

Query: 1052 EGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQG 1111
                              ++  LP          + D   +  QLR   +L+ +R+  Q 
Sbjct: 653  ------------------NDEKLP---------FEFDSKRIVQQLRACGVLETIRISAQS 685

Query: 1112 YPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVF 1171
            YP    + EF  R+ +L   +TK   +     D++   + +L  L  + +    G +++F
Sbjct: 686  YPSRWTYIEFYSRYGIL---MTK---QELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIF 739

Query: 1172 FRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCV---QKNIKK- 1227
            FRAG +A LE+ R ++  ++  + Q   RG+L R+ F + +   L I+     Q+ ++K 
Sbjct: 740  FRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKA 799

Query: 1228 ---------------NKGVKDWPWWKLFTTVR-PLIEVQ------LSEEQIRNKDEE--- 1262
                            K  + +    L+  +R   I +Q      L+  + R   EE   
Sbjct: 800  ITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKA 859

Query: 1263 -IQQLRSKLEKAEKERNELR--LNSDRLESRISELTSELTD---------ERNTGESASQ 1310
             I Q  ++   A +    +R  + + +L  R+  L  +L D         E+ T  +A +
Sbjct: 860  VILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALR 919

Query: 1311 LLDAETAERLRAEKEMKEL-QTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGG 1369
              D E  ++L AE E     +  Y+   K+      + +E +L +  + N E++      
Sbjct: 920  AGDVEKIQKLEAELEKAATHRRNYEEKGKRYR----DAVEEKLAKLQKHNSELETQKE-- 973

Query: 1370 EWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLK 1429
            + +LK +    E+      L ++  D ++ E++ +  LE+     +  +++ ++ +Q LK
Sbjct: 974  QIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEK---SFELKTQDYEKQIQSLK 1030

Query: 1430 KKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE-EAQREKLQREKLQREK 1488
            ++ + L  E    +  +EG+ V +  L+ +  R   ++    E E + E LQ +K+  EK
Sbjct: 1031 EEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEK 1090

Query: 1489 DMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEA-----------SL 1537
             +      S K+++ EK  +I     K +    +++D+ S+ S ++            + 
Sbjct: 1091 HVQ-----SQKREMREKMSEIT----KQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAY 1141

Query: 1538 AKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEV 1597
              +KK  R LE+  + Q++  +++   I+ L    + L  E+  +++   +E +  +   
Sbjct: 1142 EGLKKATRVLESHFQSQKDCYEKE---IEALNFKVVHLSQEINHLQKLFREENDINESIR 1198

Query: 1598 EEARQSCQKKL-----KQMEVQLEEEYEDKQKVLREKRE-LEGKLATLSDQVNRRDFESE 1651
             E  +   + +     KQ   +LE++ +D +  L E+ E ++GKL  LS+Q++R   E E
Sbjct: 1199 HEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQ-EEE 1257

Query: 1652 KRLRKDLKRTKAL-LADAQLMLDHLKNSAPSKREIAQLKNQLE-ESEFTCAAAVKARKAM 1709
               RK L+    +   + + ++D ++    +      LK Q E ESE  C    +A + +
Sbjct: 1258 GTQRKALEAQNEIHTKEKEKLIDKIQEMQEAS---DHLKKQFETESEVKCNFRQEASR-L 1313

Query: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSRLQR 1739
             +E  DL  ++D   +    L++Q+  L +
Sbjct: 1314 TLENRDLEEELDMKDRVIKKLQDQVKTLSK 1343



 Score = 91.3 bits (225), Expect = 9e-18
 Identities = 113/489 (23%), Positives = 212/489 (43%), Gaps = 74/489 (15%)

Query: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ----ESKD---- 1533
            ++LQ++ +    E   L ++L       AG  +K+  LEAEL+  ++     E K     
Sbjct: 892  QRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYR 951

Query: 1534 ---EASLAKVKKQLRDLEA-------KVKDQEEELDEQAGT--------IQMLEQAKLRL 1575
               E  LAK++K   +LE        K++++ EEL E+           +Q  E+ ++ L
Sbjct: 952  DAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLL 1011

Query: 1576 EMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGK 1635
            E   E   Q + K+++S  EE+    ++ + +  Q++  +E E+     +  E   L  +
Sbjct: 1012 EKSFELKTQDYEKQIQSLKEEI----KALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQ 1067

Query: 1636 LATLSD--------QVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQ 1687
            + T+S+        Q  + D E   + +K   R K      QL+  +      S+  +  
Sbjct: 1068 VKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVED 1127

Query: 1688 LKNQLEESE--FTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQ 1745
            L++  E+ E  F      KA + +E   +    Q D   K   AL  ++  L +E N +Q
Sbjct: 1128 LEHLNEDGELWFAYEGLKKATRVLESHFQS---QKDCYEKEIEALNFKVVHLSQEINHLQ 1184

Query: 1746 NRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVE 1805
             +L  ++ D+NE ++     V + + +   I D + Q+ E  K+KQ+L+ +L        
Sbjct: 1185 -KLFREENDINESIRHE---VTRLTSENMMIPDFKQQISELEKQKQDLEIRLN------- 1233

Query: 1806 FLEQSMVDKSLVSRQEAKIRELETRL----EFERTQVKRLESLASRLKENMEKLTEERDQ 1861
              EQ+        + + K+ EL  +L    E E TQ K LE+         E  T+E+++
Sbjct: 1234 --EQA-------EKMKGKLEELSNQLHRSQEEEGTQRKALEA-------QNEIHTKEKEK 1277

Query: 1862 RIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQAD 1921
             I      +E +  L++Q     E      ++ +  + +  +LE +L+  +   + LQ  
Sbjct: 1278 LIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQ 1337

Query: 1922 LKLAFKRIG 1930
            +K   K IG
Sbjct: 1338 VKTLSKTIG 1346



 Score = 85.1 bits (209), Expect = 6e-16
 Identities = 128/541 (23%), Positives = 239/541 (44%), Gaps = 94/541 (17%)

Query: 1498 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1557
            L+++LE+++ +  G  +K+ SL A       +  K EA L K     R+ E K K   + 
Sbjct: 894  LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDA 953

Query: 1558 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQ-MEVQLE 1616
            ++E+         AKL          Q H+ E+E++ E+++   Q   ++LK+ M+   +
Sbjct: 954  VEEKL--------AKL----------QKHNSELETQKEQIQLKLQEKTEELKEKMDNLTK 995

Query: 1617 EEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE-KRLRKDLKRTKALLADAQLMLDHL 1675
            + ++D QK  R++  LE      S ++  +D+E + + L++++K  K    D ++ L HL
Sbjct: 996  QLFDDVQKEERQRMLLEK-----SFELKTQDYEKQIQSLKEEIKALK----DEKMQLQHL 1046

Query: 1676 KN-----SAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAK----A 1726
                   S   K E+A+L  Q           VK     E EIE L  Q  D+ K     
Sbjct: 1047 VEGEHVTSDGLKAEVARLSKQ-----------VKTISEFEKEIELLQAQKIDVEKHVQSQ 1095

Query: 1727 KTALEEQLSRLQREKNE------IQNRLE-EDQEDMNELMKKHKA--AVAQASRDLAQIN 1777
            K  + E++S + ++  E      +++RL  ED E +NE  +   A   + +A+R L   +
Sbjct: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLE--S 1153

Query: 1778 DLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQ 1837
              Q+Q +   KE + L  K+  L  ++  L++       + R+E  I E        R +
Sbjct: 1154 HFQSQKDCYEKEIEALNFKVVHLSQEINHLQK-------LFREENDINESI------RHE 1200

Query: 1838 VKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEA 1897
            V RL S    + +  ++++E   Q+   E R  EQ ++++ +L +   ++     +E E 
Sbjct: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHR--SQEEEG 1258

Query: 1898 SRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSE----- 1952
            +++K        +LEA N+    + +    +I ++Q A +   +  E E  +        
Sbjct: 1259 TQRK--------ALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEA 1310

Query: 1953 -----GDSDVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLKSSS-PTSYWKSLAPDRSD 2006
                  + D++ EL+ +   +K    + K  SK       + SSS P  Y   L   R D
Sbjct: 1311 SRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKRED 1370

Query: 2007 D 2007
            +
Sbjct: 1371 E 1371



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 76/353 (21%), Positives = 161/353 (45%), Gaps = 28/353 (7%)

Query: 1247 IEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGE 1306
            ++ Q  E+QI++  EEI+ L+ +  + +       + SD L++ ++ L+ ++       E
Sbjct: 1017 LKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEF-E 1075

Query: 1307 SASQLLDAETAE-RLRAEKEMKELQTQYDALKKQM-EVMEMEVMEARLIRAAEINGEVDD 1364
               +LL A+  +     + + +E++ +   + KQ+ E  ++E + +RL  + E    +++
Sbjct: 1076 KEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRL--SVEDLEHLNE 1133

Query: 1365 DDAGGEWRLKYERAVREVDFTKKRLQQE---FEDKLEVEQQNKRQLERRLGDLQADSEES 1421
            D   GE    YE   +     +   Q +   +E ++E        L + +  LQ    E 
Sbjct: 1134 D---GELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREE 1190

Query: 1422 QRALQQLKKKCQRLTAE---LQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREK 1478
                + ++ +  RLT+E   + D K     QQ+   ELEK+++  +  L+   E+A++ K
Sbjct: 1191 NDINESIRHEVTRLTSENMMIPDFK-----QQIS--ELEKQKQDLEIRLN---EQAEKMK 1240

Query: 1479 LQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538
             + E+L  +      E  + ++ LE ++       +K++    E+Q+ S    K   + +
Sbjct: 1241 GKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETES 1300

Query: 1539 KVKKQLRDLEAKV----KDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHS 1587
            +VK   R   +++    +D EEELD +   I+ L+     L   + +    HS
Sbjct: 1301 EVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHS 1353



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 46/208 (22%), Positives = 105/208 (50%), Gaps = 20/208 (9%)

Query: 1736 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1795
            R+QR    +Q +LE+  ++ + L++K  +  A  + D+ +I  L+A+LE+A   ++  +E
Sbjct: 890  RVQR----LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEE 945

Query: 1796 KLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVK-RLESLASRLKENMEK 1854
            K +  +  VE              + AK+++  + LE ++ Q++ +L+     LKE M+ 
Sbjct: 946  KGKRYRDAVE-------------EKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDN 992

Query: 1855 LTEERDQRIAAENREKE-QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1913
            LT++    +  E R++    K  + + +D ++++  L  +      +K +L+  +E    
Sbjct: 993  LTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHV 1052

Query: 1914 ANQSLQADLKLAFKRIGDLQAAIEDEME 1941
             +  L+A++    K++  + +  E E+E
Sbjct: 1053 TSDGLKAEVARLSKQVKTI-SEFEKEIE 1079



 Score = 35.8 bits (81), Expect = 0.44
 Identities = 33/152 (21%), Positives = 74/152 (48%), Gaps = 16/152 (10%)

Query: 1823 KIRELETRLEFERTQ----VKRLESLASRLKENMEKLTE-ERDQRIAAENREKEQNKRLQ 1877
            +++ L+ +LE +  +    V++L SLA+    ++EK+ + E +   AA +R   + K   
Sbjct: 890  RVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEK--G 947

Query: 1878 RQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIE 1937
            ++ RD  EE      K A+  +   ELE   E ++   Q    +LK   +++ +L   + 
Sbjct: 948  KRYRDAVEE------KLAKLQKHNSELETQKEQIQLKLQEKTEELK---EKMDNLTKQLF 998

Query: 1938 DEMESDENEDLINSEGDSDVDSELEDRVDGVK 1969
            D+++ +E + ++  +       + E ++  +K
Sbjct: 999  DDVQKEERQRMLLEKSFELKTQDYEKQIQSLK 1030


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  295 bits (756), Expect = 2e-79
 Identities = 352/1534 (22%), Positives = 670/1534 (43%), Gaps = 237/1534 (15%)

Query: 340  IAAEEAWNETEKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILD--VDEDDVE 397
            +AA E + +  +VW+   +    +++L  +    P  KV +    +G  L+  +D    E
Sbjct: 1    MAASELYTKFARVWIPDPEEVWKSAELLKDYK--PGDKVLLLHLEEGKDLEYHLDPKTKE 58

Query: 398  KANAPSCDRL---EDLASLVYLNESSVLHTLRQRY-GASLLHTYAGPSLLVLGPRGAPAV 453
              +  + D L    DL +L YL+E +VLH LR R+  + L++TY G  L+ + P     +
Sbjct: 59   LPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPI 118

Query: 454  YSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQ 513
            Y E +++ + G    DM PHI+AVA+ AY+ M    ++QSII+ G SG+GKT S ++ ++
Sbjct: 119  YGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMR 178

Query: 514  YLATIAGISGNKVFSVEKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASA 573
            Y AT++G S ++    EK  A   ++E+ GN+ T  N N++RF + + + FD+  ++  A
Sbjct: 179  YFATVSG-SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGA 237

Query: 574  SIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPE 633
            +++T LLEK RV  +   E  +++FY L A         L L + A+N  +     +   
Sbjct: 238  NMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGN-ADNFNYTKQGGSPVI 296

Query: 634  EKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHE 693
            E    A++ +  + A  +LGIS   Q   + ILA I HLG  G T   A++      +HE
Sbjct: 297  EGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIP-PKHE 355

Query: 694  WAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLE 753
                   L+G   EE+   +   +     L  +T     P           KL A    +
Sbjct: 356  PLCIFCDLMGVDYEEMCHWLCHRK-----LATATETYIKPIS---------KLQATNARD 401

Query: 754  GMAAGLYSELFTLLVSLVNRALKSS--QHSLCSMMIVDTPGFQNPEQGGSARGASFEELC 811
             +A  +Y++LF  +V  VN+AL S+  QHS     ++D  GF+  E        SFE+ C
Sbjct: 402  ALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIG--VLDIYGFETFEIN------SFEQFC 453

Query: 812  HNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLA 871
             NY  ++LQ+ F+   F  E E Y +E I                 +D   +Q  +  + 
Sbjct: 454  INYANEKLQQQFNMHVFKLEQEEYMKEQIPWTL-------------IDFYDNQPCINLI- 499

Query: 872  RTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGH 931
              +   G+L LL+EE  +P  ++DT  ++L++ +         +  L    +  +     
Sbjct: 500  --ESKLGILDLLDEECKMPKGTDDTWAQKLYNTH-------LNKCALFEKPRLSNKAFII 550

Query: 932  SHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGL 991
             H  + VEY   G+L   K +   +   ++L+ S+ K++  LF         +S + A  
Sbjct: 551  QHFADKVEYQCEGFLEKNK-DTVFEEQIKVLKSSKFKMLPELF---QDDEKAISPTSATS 606

Query: 992  EGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVA 1051
             G + L  R      K     MA   KK++  Q +  +  L++T+  +  H+V C  P  
Sbjct: 607  SGRTPLT-RTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKP-- 663

Query: 1052 EGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQG 1111
                              ++   P            D      QLR   +L+ +R+   G
Sbjct: 664  ------------------NDFKFP---------FTFDEKRAVQQLRACGVLETIRISAAG 696

Query: 1112 YPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVF 1171
            +P    + EF  R+ VL         +  ++ D ++  + +LE L L+K     G +++F
Sbjct: 697  FPSRWTYQEFFSRYRVLMK-------QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIF 749

Query: 1172 FRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHF---------KKRKIQDLAIRCVQ 1222
            FRAG +A LE+ R ++        Q   RG+L R+ +          +R ++    RC  
Sbjct: 750  FRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYA 809

Query: 1223 KNIKKNKGVK-DWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELR 1281
            K +++ K       +W+++  VR   +++ +   +          R++  K  +E   + 
Sbjct: 810  KFLRRTKAATIIQKYWRMY-VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAV- 867

Query: 1282 LNSDRLESRISELTSELTDERNTGESASQLLDAETA-ERLRAEKEMKELQTQYDALKKQM 1340
                 ++ R+    +    +R    S   ++  +    R+ A++E+K+L+ +  ++++  
Sbjct: 868  ----IIQKRVRGWLARTHYKR----SMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYK 919

Query: 1341 EV---MEMEVMEARLIRAAEINGEVDDDDAGGEWRLK--------YERAVREVDFTKKRL 1389
            ++   ME ++M        ++  +VD+ +   +  ++        Y     ++    +RL
Sbjct: 920  KLHIGMENKIM--------QLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERL 971

Query: 1390 QQEFEDKLEVEQQNKRQLERRLGDLQADSEES-------QRALQQLKKKCQRLTAEL-QD 1441
            Q   E++ +V       L+  +  L+ D E++       +    + K++ ++L + L ++
Sbjct: 972  QLS-EEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEE 1030

Query: 1442 TKLHLEGQQVRNHEL--------EKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
              L  + ++  NH +        E  +++   E  Q   +   E+L+ + L  E   L  
Sbjct: 1031 NTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEE 1090

Query: 1494 EAFSLKQQL------------EEKDMDIAGFTQKVVSLE-AELQDISSQESK-------- 1532
                LK+++                   +  ++ + S E AE++DI S+  +        
Sbjct: 1091 RYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPL 1150

Query: 1533 DEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMES 1592
            D +   K++K++ +LE + +  ++ELD +       E+  LR + + E   Q    E+E 
Sbjct: 1151 DMSLFLKLQKRVTELEQEKQVMQDELDRK-------EEQVLRSKAKEEERPQIRGAELEY 1203

Query: 1593 RDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREK-------------RELEGKLATL 1639
               + +E  +S  KKLK        E  + +K L EK             R L  +L ++
Sbjct: 1204 ESLKRQEL-ESENKKLK-------NELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSV 1255

Query: 1640 SDQVNRRDFESEKRLRKDL---------KRTKALLADAQLMLDHLKNSAPSKREIAQLKN 1690
            S++++ R  E    LR  L         K  K  + D+ ++L+ ++     K EIAQ   
Sbjct: 1256 SEELDVRK-EEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQ-KMKDKGEIAQAYI 1313

Query: 1691 QLEESEFTCAAAVKARK--------AMEVEIEDL-------------HLQIDDIAKAKTA 1729
             L+E+     + ++++K        A+  EI+ L             +LQ+   A+ + +
Sbjct: 1314 GLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEAS 1373

Query: 1730 LEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHK 1763
            L+ +++RL  E  ++  +LE+  + + +L K+ K
Sbjct: 1374 LQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLK 1407



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 122/576 (21%), Positives = 243/576 (42%), Gaps = 102/576 (17%)

Query: 1419 EESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE-----LEKKQRRFDSELSQAHEE 1473
            + S  A+  L+   +R+ A+ +  KL +E + V  ++     +E K  +   ++ + +++
Sbjct: 883  KRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKD 942

Query: 1474 AQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD----------IAGFTQKVVSLEAEL 1523
                K   EKL   + +  +E   L+  LE   +           +    +++  L  +L
Sbjct: 943  Y---KCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDL 999

Query: 1524 QDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTI--QMLEQAKLRLE-MEME 1580
            +   S++   E    + K++   L + +K++   L ++   +  ++++QAK   E ME +
Sbjct: 1000 EQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKK 1059

Query: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLR---------EKRE 1631
             + +T   E++  DE     R   Q  L +   +LEE Y+D ++ +           KR 
Sbjct: 1060 LVEETKQLELDLNDE-----RLRYQNLLNEFS-RLEERYDDLKEEMTLMVHVPKPGHKRT 1113

Query: 1632 ------------LEGKLATLSDQVNRRDFESEKRLRKDL-------KRTKALLADAQLML 1672
                           ++A + D  +R +  SEK++  D+       KR   L  + Q+M 
Sbjct: 1114 DSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQ 1173

Query: 1673 DHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEE 1732
            D L      ++E   L+++ +E E          +  E+E E L  Q          LE 
Sbjct: 1174 DEL-----DRKEEQVLRSKAKEEERPQI------RGAELEYESLKRQ---------ELES 1213

Query: 1733 QLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQIND-LQAQLEEANKEKQ 1791
            +  +L+ E NE++  L E  +   E+      A       L  +++ L  + EE    + 
Sbjct: 1214 ENKKLKNELNELRKALSE--KSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRS 1271

Query: 1792 ELQEKLQALQSQVE---------FLE--QSMVDKSLVSRQEAKIRELETRLEFERTQVKR 1840
            +L  + +A+Q + +          LE  Q M DK  +++    ++E    LE +    KR
Sbjct: 1272 QLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKR 1331

Query: 1841 L-ESLASRLKENMEKLTEE--RDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEA 1897
              E+ A  L+  ++ L EE  R Q++ A+N +     R++  L+       E+ R     
Sbjct: 1332 SHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQH------EITR----L 1381

Query: 1898 SRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933
            + +  +L   LE  +   + L+  LK+  K+IG+L+
Sbjct: 1382 TNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1417



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 92/417 (22%), Positives = 170/417 (40%), Gaps = 65/417 (15%)

Query: 1625 VLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQ----LMLDHLKNSAP 1680
            V+R + ++  + AT+  Q   R F +  R RK L+  KA++   +    L   H K S  
Sbjct: 829  VVRRRYKIR-RAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887

Query: 1681 S-------------KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAK 1727
            +             KRE+ +LK +    E       K    ME +I  L  ++D+  K  
Sbjct: 888  AIIYLQCCFRRMMAKRELKKLKIEARSVE----RYKKLHIGMENKIMQLQRKVDEQNKDY 943

Query: 1728 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN 1787
              L E+L+ L+   N    +L  D E +    ++ K A  +      +I  L+  LE+  
Sbjct: 944  KCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTR 1003

Query: 1788 KEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQE------------------------AK 1823
             EK+ ++E     + + E L  ++ +++ + +QE                         +
Sbjct: 1004 SEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063

Query: 1824 IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRI----AAENREKEQNKRLQRQ 1879
             ++LE  L  ER + + L +  SRL+E  + L EE    +        R    +   + +
Sbjct: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE 1123

Query: 1880 LRDTKE--EMGELARKEAEASRKKHELEMDL--------ESLEAANQSLQADLKLAFKRI 1929
               + E  EM ++  +  E S KK  L+M L          LE   Q +Q +L    +++
Sbjct: 1124 YIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQV 1183

Query: 1930 GDLQAAIEDEME----SDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAA 1982
               +A  E+  +      E E L   E +S+ + +L++ ++ ++  LS+   P   A
Sbjct: 1184 LRSKAKEEERPQIRGAELEYESLKRQELESE-NKKLKNELNELRKALSEKSAPEVTA 1239



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 145/675 (21%), Positives = 247/675 (36%), Gaps = 219/675 (32%)

Query: 1091 LLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDE---RR 1147
            L +  LR  +    M+ Y +GY     +++F RR    A  + +K+ R Y+V      RR
Sbjct: 782  LRKKYLRMRKAAITMQRYVRGYQARC-YAKFLRR--TKAATIIQKYWRMYVVRRRYKIRR 838

Query: 1148 AVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQH 1207
            A   +L+                 +  G LAR    R         + Q   RG+LAR H
Sbjct: 839  AATIVLQS----------------YLRGFLAR-NRYRKILREHKAVIIQKRVRGWLARTH 881

Query: 1208 FK------------------KRKIQDLAI------------------------------- 1218
            +K                  KR+++ L I                               
Sbjct: 882  YKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNK 941

Query: 1219 --RCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIR-------NKDEEIQQLRSK 1269
              +C+ + +   +G+ +    KL + +  L   QLSEE+ +       +  EEI +LR  
Sbjct: 942  DYKCLVEKLTNLEGIYNSETEKLRSDLERL---QLSEEEAKVATGRVLSLQEEIAKLRKD 998

Query: 1270 LEKAEKERNELRLNSDRLESRISELTSELTDE-------------------RNTGESASQ 1310
            LE+   E+  +  ++DR +    +L S L +E                   +   E+  +
Sbjct: 999  LEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEK 1058

Query: 1311 LLDAETA--------ERLRAEK---EMKELQTQYDALKKQMEVM-------------EME 1346
             L  ET         ERLR +    E   L+ +YD LK++M +M                
Sbjct: 1059 KLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHS 1118

Query: 1347 VMEARLIRAAEINGEVDDDDAGGEWR------------LKYERAVREVDFTKKRLQQEFE 1394
              E+  I ++EI  E++D  +  E              LK ++ V E++  K+ +Q E +
Sbjct: 1119 SNESEYIFSSEI-AEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELD 1177

Query: 1395 DK---------------------LEVEQQNKRQLERRLGDLQADSEESQRALQQ------ 1427
             K                     LE E   +++LE     L+ +  E ++AL +      
Sbjct: 1178 RKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEV 1237

Query: 1428 ----------LKKKCQRLTAELQDTK---LHLEGQQVRNHE-----------------LE 1457
                      L ++   ++ EL   K   L L  Q V   E                 LE
Sbjct: 1238 TAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLE 1297

Query: 1458 KKQRRFDS-ELSQAH---EEAQR---EKLQREKL--QREKDMLLAEAFSLK------QQL 1502
              Q+  D  E++QA+   +E  R    +LQ +K   + E + L  E  SLK      QQL
Sbjct: 1298 DVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQL 1357

Query: 1503 EEKDMDI-------AGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQE 1555
              +++ +       A    ++  L  E  D+  Q  K + ++ K+KKQL+    K+ + E
Sbjct: 1358 LAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1417

Query: 1556 EELDEQAGTIQMLEQ 1570
                E     Q++++
Sbjct: 1418 VGQMENISPGQIIDE 1432


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  294 bits (753), Expect = 5e-79
 Identities = 364/1580 (23%), Positives = 684/1580 (43%), Gaps = 237/1580 (15%)

Query: 340  IAAEEAWNETEKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILD--VDEDDVE 397
            +AA E + +  +VW+   +    +++L  +    P  KV +    +G  L+  +D    E
Sbjct: 1    MAASELYTKFARVWIPDPEEVWKSAELLKDYK--PGDKVLLLHLEEGKDLEYHLDPKTKE 58

Query: 398  KANAPSCDRL---EDLASLVYLNESSVLHTLRQRY-GASLLHTYAGPSLLVLGPRGAPAV 453
              +  + D L    DL +L YL+E +VLH LR R+  + L++TY G  L+ + P     +
Sbjct: 59   LPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPI 118

Query: 454  YSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQ 513
            Y E +++ + G    DM PHI+AVA+ AY+ M    ++QSII+ G SG+GKT S ++ ++
Sbjct: 119  YGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMR 178

Query: 514  YLATIAGISGNKVFSVEKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASA 573
            Y AT++G S ++    EK  A   ++E+ GN+ T  N N++RF + + + FD+  ++  A
Sbjct: 179  YFATVSG-SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGA 237

Query: 574  SIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPE 633
            +++T LLEK RV  +   E  +++FY L A         L L + A+N  +     +   
Sbjct: 238  NMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGN-ADNFNYTKQGGSPVI 296

Query: 634  EKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHE 693
            E    A++ +  + A  +LGIS   Q   + ILA I HLG  G T   A++      +HE
Sbjct: 297  EGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIP-PKHE 355

Query: 694  WAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLE 753
                   L+G   EE+   +   +     L  +T     P           KL A    +
Sbjct: 356  PLCIFCDLMGVDYEEMCHWLCHRK-----LATATETYIKPIS---------KLQATNARD 401

Query: 754  GMAAGLYSELFTLLVSLVNRALKSS--QHSLCSMMIVDTPGFQNPEQGGSARGASFEELC 811
             +A  +Y++LF  +V  VN+AL S+  QHS     ++D  GF+  E        SFE+ C
Sbjct: 402  ALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIG--VLDIYGFETFEIN------SFEQFC 453

Query: 812  HNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLA 871
             NY  ++LQ+ F+   F  E E Y +E I                 +D   +Q  +  + 
Sbjct: 454  INYANEKLQQQFNMHVFKLEQEEYMKEQIPWTL-------------IDFYDNQPCINLI- 499

Query: 872  RTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGH 931
              +   G+L LL+EE  +P  ++DT  ++L++ +         +  L    +  +     
Sbjct: 500  --ESKLGILDLLDEECKMPKGTDDTWAQKLYNTH-------LNKCALFEKPRLSNKAFII 550

Query: 932  SHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGL 991
             H  + VEY   G+L   K +   +   ++L+ S+ K++  LF         +S + A  
Sbjct: 551  QHFADKVEYQCEGFLEKNK-DTVFEEQIKVLKSSKFKMLPELF---QDDEKAISPTSATS 606

Query: 992  EGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVA 1051
             G + L  R      K     MA   KK++  Q +  +  L++T+  +  H+V C  P  
Sbjct: 607  SGRTPLT-RTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKP-- 663

Query: 1052 EGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQG 1111
                              ++   P            D      QLR   +L+ +R+   G
Sbjct: 664  ------------------NDFKFP---------FTFDEKRAVQQLRACGVLETIRISAAG 696

Query: 1112 YPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVF 1171
            +P    + EF  R+ VL         +  ++ D ++  + +LE L L+K     G +++F
Sbjct: 697  FPSRWTYQEFFSRYRVLMK-------QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIF 749

Query: 1172 FRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHF---------KKRKIQDLAIRCVQ 1222
            FRAG +A LE+ R ++        Q   RG+L R+ +          +R ++    RC  
Sbjct: 750  FRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYA 809

Query: 1223 KNIKKNKGVK-DWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELR 1281
            K +++ K       +W+++  VR   +++ +   +          R++  K  +E   + 
Sbjct: 810  KFLRRTKAATIIQKYWRMY-VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAV- 867

Query: 1282 LNSDRLESRISELTSELTDERNTGESASQLLDAETA-ERLRAEKEMKELQTQYDALKKQM 1340
                 ++ R+    +    +R    S   ++  +    R+ A++E+K+L+ +  ++++  
Sbjct: 868  ----IIQKRVRGWLARTHYKR----SMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYK 919

Query: 1341 EV---MEMEVMEARLIRAAEINGEVDDDDAGGEWRLK--------YERAVREVDFTKKRL 1389
            ++   ME ++M        ++  +VD+ +   +  ++        Y     ++    +RL
Sbjct: 920  KLHIGMENKIM--------QLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERL 971

Query: 1390 QQEFEDKLEVEQQNKRQLERRLGDLQADSEES-------QRALQQLKKKCQRLTAEL-QD 1441
            Q   E++ +V       L+  +  L+ D E++       +    + K++ ++L + L ++
Sbjct: 972  QLS-EEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEE 1030

Query: 1442 TKLHLEGQQVRNHEL--------EKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
              L  + ++  NH +        E  +++   E  Q   +   E+L+ + L  E   L  
Sbjct: 1031 NTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEE 1090

Query: 1494 EAFSLKQQL------------EEKDMDIAGFTQKVVSLE-AELQDISSQESK-------- 1532
                LK+++                   +  ++ + S E AE++DI S+  +        
Sbjct: 1091 RYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPL 1150

Query: 1533 DEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMES 1592
            D +   K++K++ +LE + +  ++ELD +       E+  LR + + E   Q    E+E 
Sbjct: 1151 DMSLFLKLQKRVTELEQEKQVMQDELDRK-------EEQVLRSKAKEEERPQIRGAELEY 1203

Query: 1593 RDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREK-------------RELEGKLATL 1639
               + +E  +S  KKLK        E  + +K L EK             R L  +L ++
Sbjct: 1204 ESLKRQEL-ESENKKLK-------NELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSV 1255

Query: 1640 SDQVNRRDFESEKRLRKDL---------KRTKALLADAQLMLDHLKNSAPSKREIAQLKN 1690
            S++++ R  E    LR  L         K  K  + D+ ++L+ ++     K EIAQ   
Sbjct: 1256 SEELDVRK-EEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQ-KMKDKGEIAQAYI 1313

Query: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE--------KN 1742
             L+E+  + A           E  +L L  + + +A   LE QL   +R         + 
Sbjct: 1314 GLKETNRSSALDYHELN----EDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRG 1369

Query: 1743 EIQNRLEEDQEDMNELMK--------KHKAAVAQASRDLAQIN-DLQAQLEEANKEKQEL 1793
            EIQ+  EE+      L +        + +A++      L   N DL  QLE+ +K  ++L
Sbjct: 1370 EIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKL 1429

Query: 1794 QEKLQALQSQVEFLEQSMVD 1813
            +++L+    ++  LE   ++
Sbjct: 1430 KKQLKVFAKKIGELEVGQME 1449



 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 121/590 (20%), Positives = 246/590 (41%), Gaps = 103/590 (17%)

Query: 1419 EESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE-----LEKKQRRFDSELSQAHEE 1473
            + S  A+  L+   +R+ A+ +  KL +E + V  ++     +E K  +   ++ + +++
Sbjct: 883  KRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKD 942

Query: 1474 AQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD----------IAGFTQKVVSLEAEL 1523
                K   EKL   + +  +E   L+  LE   +           +    +++  L  +L
Sbjct: 943  Y---KCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDL 999

Query: 1524 QDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTI--QMLEQAKLRLE-MEME 1580
            +   S++   E    + K++   L + +K++   L ++   +  ++++QAK   E ME +
Sbjct: 1000 EQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKK 1059

Query: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLR---------EKRE 1631
             + +T   E++  DE     R   Q  L +   +LEE Y+D ++ +           KR 
Sbjct: 1060 LVEETKQLELDLNDE-----RLRYQNLLNEFS-RLEERYDDLKEEMTLMVHVPKPGHKRT 1113

Query: 1632 ------------LEGKLATLSDQVNRRDFESEKRLRKDL-------KRTKALLADAQLML 1672
                           ++A + D  +R +  SEK++  D+       KR   L  + Q+M 
Sbjct: 1114 DSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQ 1173

Query: 1673 DHLKNSAPSKREIAQLKNQLEESEFTCAAAVK----ARKAMEVEIEDLHLQIDDIAKAKT 1728
            D L      + ++ + K + EE      A ++     R+ +E E + L  +++++ KA +
Sbjct: 1174 DELDRK---EEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALS 1230

Query: 1729 -------------ALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQ 1775
                         A    + +L     E+  R EE     ++L+ + +A   Q   D   
Sbjct: 1231 EKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAI--QPKDDKNT 1288

Query: 1776 INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ----------EAKIR 1825
            + D    LE+  K K +  E  QA     E    S +D   ++            +   R
Sbjct: 1289 MTDSTILLEDVQKMKDK-GEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANR 1347

Query: 1826 ELETRLEFERTQVKRLESLASRLKENMEKLTEE--RDQRIAAENREKEQNKRLQRQLRDT 1883
             LE++L+   +Q +  E+ A  L+  ++ L EE  R Q++ A+N +     R++  L+  
Sbjct: 1348 LLESQLQ---SQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQH- 1403

Query: 1884 KEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933
                 E+ R     + +  +L   LE  +   + L+  LK+  K+IG+L+
Sbjct: 1404 -----EITR----LTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 92/417 (22%), Positives = 170/417 (40%), Gaps = 65/417 (15%)

Query: 1625 VLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQ----LMLDHLKNSAP 1680
            V+R + ++  + AT+  Q   R F +  R RK L+  KA++   +    L   H K S  
Sbjct: 829  VVRRRYKIR-RAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887

Query: 1681 S-------------KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAK 1727
            +             KRE+ +LK +    E       K    ME +I  L  ++D+  K  
Sbjct: 888  AIIYLQCCFRRMMAKRELKKLKIEARSVE----RYKKLHIGMENKIMQLQRKVDEQNKDY 943

Query: 1728 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN 1787
              L E+L+ L+   N    +L  D E +    ++ K A  +      +I  L+  LE+  
Sbjct: 944  KCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTR 1003

Query: 1788 KEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQE------------------------AK 1823
             EK+ ++E     + + E L  ++ +++ + +QE                         +
Sbjct: 1004 SEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063

Query: 1824 IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRI----AAENREKEQNKRLQRQ 1879
             ++LE  L  ER + + L +  SRL+E  + L EE    +        R    +   + +
Sbjct: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE 1123

Query: 1880 LRDTKE--EMGELARKEAEASRKKHELEMDL--------ESLEAANQSLQADLKLAFKRI 1929
               + E  EM ++  +  E S KK  L+M L          LE   Q +Q +L    +++
Sbjct: 1124 YIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQV 1183

Query: 1930 GDLQAAIEDEME----SDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAA 1982
               +A  E+  +      E E L   E +S+ + +L++ ++ ++  LS+   P   A
Sbjct: 1184 LRSKAKEEERPQIRGAELEYESLKRQELESE-NKKLKNELNELRKALSEKSAPEVTA 1239



 Score = 48.1 bits (113), Expect = 9e-05
 Identities = 76/335 (22%), Positives = 143/335 (42%), Gaps = 62/335 (18%)

Query: 1248 EVQLSEEQI---RNKDEEIQQLR-SKLEKAEKERNELRLNSDRLESRISELTSELTDERN 1303
            E+   EEQ+   + K+EE  Q+R ++LE    +R EL   + +L++ ++EL   L+++  
Sbjct: 1175 ELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEK-- 1232

Query: 1304 TGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVM--EARLIRAAEINGE 1361
               SA ++    TA    A + + E   Q  ++ ++++V + EV+   ++L+   E    
Sbjct: 1233 ---SAPEV----TAPGAPAYRVLME---QLTSVSEELDVRKEEVLILRSQLVSQKEAIQP 1282

Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ------QNKRQLERRLGDLQ 1415
             DD +   +  +  E              Q+ +DK E+ Q      +  R       +L 
Sbjct: 1283 KDDKNTMTDSTILLEDV------------QKMKDKGEIAQAYIGLKETNRSSALDYHELN 1330

Query: 1416 ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQ 1475
             D E      + LK+  + L ++LQ  K        R+HE E +  R   E+    EE  
Sbjct: 1331 EDGE-LWLVYEGLKQANRLLESQLQSQK--------RSHENEAEALR--GEIQSLKEENN 1379

Query: 1476 REKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEA 1535
            R++            LLA+   L  +   +    A    ++  L  E  D+  Q  K + 
Sbjct: 1380 RQQ-----------QLLAQNLQLPPEARIE----ASLQHEITRLTNENLDLMEQLEKQDK 1424

Query: 1536 SLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQ 1570
            ++ K+KKQL+    K+ + E    E     Q++++
Sbjct: 1425 TVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDE 1459


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  286 bits (732), Expect = 1e-76
 Identities = 366/1618 (22%), Positives = 682/1618 (42%), Gaps = 226/1618 (13%)

Query: 344  EAWNETEKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAI---LDVDEDDVEKAN 400
            E +++  +VW+   D    +++L +++    +  ++++L+ +  +   +DV  + +    
Sbjct: 5    ELYSQCTRVWIPDPDEVWRSAEL-TKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLR 63

Query: 401  APSCDRLE-DLASLVYLNESSVLHTLRQRY-GASLLHTYAGPSLLVLGPRGAPAVYSEKV 458
             P     E DL +L YL+E +VLH L+ R+  ++ ++TY G  L+ + P     +Y + V
Sbjct: 64   NPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDV 123

Query: 459  MHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATI 518
            ++ + G    DM PHI+AVA+ AY+ M    ++QSII+ G SG+GKT S ++ ++Y AT+
Sbjct: 124  IYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATV 183

Query: 519  AGISGNKVFSVEKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTM 578
             G S ++    EK  A   ++EA GN+ T  N N++RF + + + FD+   +  A+++T 
Sbjct: 184  GG-SASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTY 242

Query: 579  LLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKA 638
            LLEK RV  +   E  +++FY L A        EL L   AE+  +         E    
Sbjct: 243  LLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTS-AEDFFYTSQGGDTSIEGVDD 301

Query: 639  AQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKA 698
            A+ F K + A  +LG+    Q + + I+A+I HLG+     E          +  +    
Sbjct: 302  AEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNF 361

Query: 699  AYLLGCSLEELSSAIF--KHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMA 756
              LLG    ++   +   K      T  ++ S +Q                 +     +A
Sbjct: 362  CRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQ----------------VINARNALA 405

Query: 757  AGLYSELFTLLVSLVNRALKSS--QHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNY 814
              +Y++LF  +V  +N+AL +S  QHS     ++D  GF+  E        SFE+ C NY
Sbjct: 406  KHIYAQLFGWIVEHINKALHTSLKQHSFIG--VLDIYGFETFEVN------SFEQFCINY 457

Query: 815  TQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTD 874
              ++LQ+ F+   F  E E Y +E I     D      D+   +D              +
Sbjct: 458  ANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFY----DNQPCID------------LIE 501

Query: 875  EARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHG 934
               G+L LL+EE  VP  ++    ++L   Y      +  Q P + ++    F++   H 
Sbjct: 502  AKLGILDLLDEECKVPKGTDQNWAQKL---YDRHSSSQHFQKPRMSNTA---FII--VHF 553

Query: 935  TNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGG 994
             + VEY   G+L    ++   +    +L+ S+  ++++LF         +  +  G    
Sbjct: 554  ADKVEYLSDGFLE-KNRDTVYEEQINILKASKFPLVADLF---HDDKDPVPATTPGKGSS 609

Query: 995  SQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGW 1054
            S++++R A    K          KK++  Q +  +  L++T+  +  H+V C  P     
Sbjct: 610  SKISVRSARPPMKVSN----KEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKP----- 660

Query: 1055 AGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPD 1114
                           ++  LP            D      QLR   +L+ +R+   GYP 
Sbjct: 661  ---------------NDEKLP---------FHFDPKRAVQQLRACGVLETIRISAAGYPS 696

Query: 1115 HMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRA 1174
               + +F  R+ V    L KK  R     D++     +LE L  +      G +++FFRA
Sbjct: 697  RWAYHDFFNRYRV----LVKK--RELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRA 750

Query: 1175 GTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDW 1234
            G +A LE+ R ++      + Q   RG+L +  + + K   L ++               
Sbjct: 751  GQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQ--------------- 795

Query: 1235 PWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISEL 1294
                     R  +  +L+E   R +   + Q   ++++A +    +R    R    I   
Sbjct: 796  ------RYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVR----RAAVVIQAF 845

Query: 1295 TSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDA------------LKKQMEV 1342
            T  +   R   +   +       + +R     +  Q   DA             +++++ 
Sbjct: 846  TRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKA 905

Query: 1343 MEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQ 1402
            + +E   A  ++   +  E           ++ +R + E +   K L ++          
Sbjct: 906  LRIEARSAEHLKRLNVGME--------NKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTM 957

Query: 1403 NKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRN-HELEK--- 1458
               +L++ L   Q    E      +L+++ + L  ELQ  + H E + + + H  EK   
Sbjct: 958  EVERLKKELVHYQQSPGEDTSL--RLQEEVESLRTELQ--RAHSERKILEDAHSREKDEL 1013

Query: 1459 KQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS---LKQQLEEKDMDIAGFTQK 1515
            ++R  D E   A  + ++E+L  + L + KD     +     +K++LEE+        ++
Sbjct: 1014 RKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKE 1073

Query: 1516 VVSLEAELQDISSQES--KDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKL 1573
               LE    ++  + +  K      +       LE+          E   T   L+Q + 
Sbjct: 1074 YSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVE- 1132

Query: 1574 RLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE-EYEDKQKVLREKREL 1632
             + +E   M  T   +++ R  E+E+ R       K+++VQLE+ E +D +KV  E  + 
Sbjct: 1133 EIGLEKAAMDMTVFLKLQKRVRELEQER-------KKLQVQLEKREQQDSKKVQAEPPQT 1185

Query: 1633 EGKLATLSD----QVNRRDFESE-KRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQ 1687
            +  L   +D     + R++ ESE K+L+ DL   +  +AD Q   ++  + +P    +  
Sbjct: 1186 DIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVAD-QATQNNSSHGSPDSYSL-- 1242

Query: 1688 LKNQLEESEFTCAAAVKARKAMEVEIED---LHLQIDDIAKAKTALEEQLSRLQREKNEI 1744
            L NQL+           A + +EV  E+   L  QI    + + A       +    +  
Sbjct: 1243 LLNQLK----------LAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWP 1292

Query: 1745 QNRLEEDQEDMNELMK---------------KHKAAVAQASRDLAQINDLQAQLEEANKE 1789
             +    DQED  E                       +  A + L Q+    A+L EA  +
Sbjct: 1293 NSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQV----ARLLEAQLQ 1348

Query: 1790 KQEL--QEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEF-ERTQVKRLESLAS 1846
             Q L  +E+++ L++Q+E L++ M DK   +  +  +   E ++EF  + ++ RL +   
Sbjct: 1349 AQSLEHEEEVEHLKAQLEALKEEM-DKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENL 1407

Query: 1847 RLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHEL 1904
             LKE +EKL          E  E++  K+L+  ++  K +  E A+  A++ RK+HEL
Sbjct: 1408 DLKELVEKL----------EKNERKLKKQLKIYMK--KAQDLEAAQALAQSERKRHEL 1453



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 136/666 (20%), Positives = 280/666 (42%), Gaps = 87/666 (13%)

Query: 1193 TLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS 1252
            T  Q   RG++AR+HF++ +   + I+C  + +K  + +K          +R  IE + +
Sbjct: 865  TTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELK---------ALR--IEARSA 913

Query: 1253 EEQIR---NKDEEIQQLRSKLEKAEKE----RNELRLNSDRLESRISELTSELTD-ERNT 1304
            E   R     + ++ QL+ K+++  KE      +L + +      +  L  EL   +++ 
Sbjct: 914  EHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSP 973

Query: 1305 GESASQLLDAET----AERLRAEKEMKELQTQYDALKKQM--EVMEMEVMEARLIRAAE- 1357
            GE  S  L  E      E  RA  E K L+  +   K ++   V ++E   A L    E 
Sbjct: 974  GEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQ 1033

Query: 1358 INGEV--DDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQ--NKRQ----LER 1409
            +N ++     D   +  +K     +E++  + R Q   ++  ++EQ+  N R     +++
Sbjct: 1034 LNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQ 1093

Query: 1410 RLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQR------RF 1463
              G  +  S +S  +L+         T+E+ DT+  L  QQV    LEK         + 
Sbjct: 1094 TPGHRRNPSNQS--SLESDSNYPSISTSEIGDTEDAL--QQVEEIGLEKAAMDMTVFLKL 1149

Query: 1464 DSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAEL 1523
               + +  +E ++ ++Q EK +++         S K Q E    DI       +   A+L
Sbjct: 1150 QKRVRELEQERKKLQVQLEKREQQD--------SKKVQAEPPQTDID------LDPNADL 1195

Query: 1524 QDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMR 1583
               S +  + E+   K+K  L +L   V DQ  + +   G+         +L++  E + 
Sbjct: 1196 AYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELE 1255

Query: 1584 QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV 1643
                + +  R + V   ++    +  +  +     + + +K + ++  +E          
Sbjct: 1256 VRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNS 1315

Query: 1644 NRRDF-----ESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFT 1698
               D+     + E  L     +  A L +AQL    L++    + E+  LK QLE     
Sbjct: 1316 KTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEH----EEEVEHLKAQLE----- 1366

Query: 1699 CAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL 1758
               A+K     + +     L +   A+ +  +++++SRL  E  +++  +E+ +++  +L
Sbjct: 1367 ---ALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKL 1423

Query: 1759 MKKHKAAVAQASRDLAQINDLQA--QLEEANKEKQELQEKLQALQSQVEF---LEQSMVD 1813
             K+ K  + +A        DL+A   L ++ +++ EL  ++   + + +F   LE    D
Sbjct: 1424 KKQLKIYMKKA-------QDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKED 1476

Query: 1814 KSLVSR 1819
            ++L+ R
Sbjct: 1477 EALLIR 1482


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  228 bits (582), Expect = 4e-59
 Identities = 254/1035 (24%), Positives = 445/1035 (42%), Gaps = 168/1035 (16%)

Query: 407  LEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGP-RGAPAVYSEKVMHMFKGC 465
            ++D+ASL  L+  S+++ L QRY  + ++TY G  L  + P +    +Y    M  +   
Sbjct: 65   VDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRR 124

Query: 466  RREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGIS--- 522
               ++ PHI+A+A   YR +     +Q I++ G SG+GKT S + ++++L+ I+  S   
Sbjct: 125  HLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSLEL 184

Query: 523  --GNKVFSVEKWQALYT-LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTML 579
                K   VE+     + ++EAFGN+ T+ N N++RF + + L+  Q G +    I   L
Sbjct: 185  SLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYL 244

Query: 580  LEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAA 639
            LEK RV R+   E  +++FY LLA  +   R E +L+     N   +      E+K  + 
Sbjct: 245  LEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLS--TPENYHYLNQSGCVEDKTISD 302

Query: 640  QQ-FSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKA 698
            Q+ F ++  AM V+  S +E +    +LA I HLG      E   AG  Q +      ++
Sbjct: 303  QESFREVITAMDVMQFSKEEVREVSRLLAGILHLG----NIEFITAGGAQVSFKTALGRS 358

Query: 699  AYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAG 758
            A LLG    +L+ A+          QRS   R     + L         A++  + +A  
Sbjct: 359  AELLGLDPTQLTDAL---------TQRSMFLRGEEILTPLN-----VQQAVDSRDSLAMA 404

Query: 759  LYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDR 818
            LY+  F  ++  +N  +K ++    S+ I+D  GF+N E         FE+   NY  ++
Sbjct: 405  LYACCFEWVIKKINSRIKGNE-DFKSIGILDIFGFENFEVN------HFEQFNINYANEK 457

Query: 819  LQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARG 878
            LQ  F++  F  E   Y  E   L ++D++         +D      L+      ++  G
Sbjct: 458  LQEYFNKHIFSLEQLEYSREG--LVWEDID--------WIDNGECLDLI------EKKLG 501

Query: 879  LLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWV 938
            LL L+ EE+  P A++ TLLE+L S +       K +  + +         G  H    V
Sbjct: 502  LLALINEESHFPQATDSTLLEKLHSQHANNHFYVKPRVAVNN--------FGVKHYAGEV 553

Query: 939  EYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLF---LGRAGSATVLSGSIAGLEGGS 995
            +Y+V G L    ++    +   LL++S+   I +LF     R    T+  GS        
Sbjct: 554  QYDVRGILE-KNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGS-------- 604

Query: 996  QLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWA 1055
                                 ++ ++  Q K  + +L+ T+  S   FV C  P  +   
Sbjct: 605  -------------------KHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQ--- 642

Query: 1056 GEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDH 1115
                              +P          Q D  ++  QLR S +L+ +R+ + GY   
Sbjct: 643  -----------------KMPD---------QFDQAVVLNQLRYSGMLETVRIRKAGYAVR 676

Query: 1116 MVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAG 1175
              F +F +R+ VL  +L        +  D R     LL+  D   S   +G ++VF R  
Sbjct: 677  RPFQDFYKRYKVLMRNLA-------LPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRES 729

Query: 1176 TLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKK---------RKIQDLAIRCVQKNIK 1226
               +LE++R+E+ S    + +A   G+LAR+ ++K         +  +   +R    ++K
Sbjct: 730  LEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLK 789

Query: 1227 KNKGV--KDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEK-AEKERNELRLN 1283
            K   V  K           R L+  +  +E+ + ++EE ++ R + E+  E+ER E  L 
Sbjct: 790  KAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELR 849

Query: 1284 SD-----RLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKK 1338
            +      R +  +  L     +   T E   Q  + +  E LR EKE+++LQ       +
Sbjct: 850  AQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ-------R 902

Query: 1339 QMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLE 1398
              E  E+ + EA L +  E                + ++ +R ++    R  QEF + L 
Sbjct: 903  MKEQQELSLTEASLQKLQE----------------RRDQELRRLEEEACRAAQEFLESLN 946

Query: 1399 VEQQNK--RQLERRL 1411
             ++ ++  R +ER L
Sbjct: 947  FDEIDECVRNIERSL 961



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 57/263 (21%), Positives = 118/263 (44%), Gaps = 31/263 (11%)

Query: 1365 DDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERR--LGDLQADS---- 1418
            D +  EW+L   +      F ++ L+Q+ E + E E  +   + R   LG L        
Sbjct: 711  DASNSEWQLGKTKV-----FLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKV 765

Query: 1419 -------EESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAH 1471
                   +++ RA   L+++   L       +  L GQ  R    +    + + E  +  
Sbjct: 766  LYCVVIIQKNYRAFL-LRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQ 824

Query: 1472 EEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGF--TQKVVSLEAELQDISSQ 1529
            EE +++K + E+ +RE++   AE  + +++   K  ++     +QK   L  EL+    +
Sbjct: 825  EEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELE--KQK 882

Query: 1530 ESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAK----LRLEMEMERMRQT 1585
            E+K    + +++K++ DL+   + QE  L E   ++Q L++ +     RLE E  R  Q 
Sbjct: 883  ENKQVEEILRLEKEIEDLQRMKEQQELSLTE--ASLQKLQERRDQELRRLEEEACRAAQE 940

Query: 1586 HSKEMESRDEEVEEARQSCQKKL 1608
              + +    +E++E  ++ ++ L
Sbjct: 941  FLESLNF--DEIDECVRNIERSL 961



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 66/277 (23%), Positives = 114/277 (41%), Gaps = 36/277 (12%)

Query: 1733 QLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQE 1792
            QL   +RE+ E + + EE+++   E  ++ +    +A        +L+AQ EE  +++QE
Sbjct: 810  QLLAEKREQEEKKKQEEEEKKKREEEERERERERREA--------ELRAQQEEETRKQQE 861

Query: 1793 LQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852
            L E LQ  Q + E   +  ++K   ++Q  +I  LE  +E +  ++K  + L S  + ++
Sbjct: 862  L-EALQKSQKEAELTRE--LEKQKENKQVEEILRLEKEIE-DLQRMKEQQEL-SLTEASL 916

Query: 1853 EKLTEERDQRIAAENRE-----------------KEQNKRLQRQLRDTKEEMGELARKEA 1895
            +KL E RDQ +     E                  E  + ++R L    E   ELA    
Sbjct: 917  QKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESAC 976

Query: 1896 EASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDS 1955
            E     +  +   E  E  ++  +AD   AFK   D     E          +  S+  S
Sbjct: 977  EEKPNFNFSQPYPE--EEVDEGFEAD-DDAFK---DSPNPSEHGHSDQRTSGIRTSDDSS 1030

Query: 1956 DVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLKSSS 1992
            + D  + D V             + +  D GSL +SS
Sbjct: 1031 EEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSS 1067



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 31/100 (31%), Positives = 57/100 (57%), Gaps = 13/100 (13%)

Query: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
            ++  R L A+ ++QEE+  ++       E+ K R E E ER R+    E+ ++ EE    
Sbjct: 805  RRVYRQLLAEKREQEEKKKQEE------EEKKKREEEERERERERREAELRAQQEEETRK 858

Query: 1601 RQ---SCQKKLKQMEV--QLEEEYEDKQ--KVLREKRELE 1633
            +Q   + QK  K+ E+  +LE++ E+KQ  ++LR ++E+E
Sbjct: 859  QQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIE 898



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 67/281 (23%), Positives = 123/281 (43%), Gaps = 34/281 (12%)

Query: 1531 SKDEASLAKVKKQLRD-LEAKV-KDQEEELDEQAGTIQ-----MLEQAKLRLEMEMERMR 1583
            S  E  L K K  LR+ LE K+ K +EEE+   A  I+      L + + R  +    + 
Sbjct: 713  SNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVII 772

Query: 1584 QTHSKE--MESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSD 1641
            Q + +   +  R   +++A    QK+L+    +        +++L EKRE E K     +
Sbjct: 773  QKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIAR-----RVYRQLLAEKREQEEKKKQEEE 827

Query: 1642 QVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAA 1701
            +  +R+ E  +R R+   R +A L   Q      +     ++E+  L+   +E+E T   
Sbjct: 828  EKKKREEEERERERE---RREAELRAQQ------EEETRKQQELEALQKSQKEAELTREL 878

Query: 1702 AVKARKAMEVEIEDLHLQIDDIAKAK-----TALEEQLSRLQREKNEIQNRLEED----- 1751
              +       EI  L  +I+D+ + K     +  E  L +LQ  +++   RLEE+     
Sbjct: 879  EKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAA 938

Query: 1752 QEDMNEL-MKKHKAAVAQASRDLAQINDLQAQLEEANKEKQ 1791
            QE +  L   +    V    R L+  ++  ++L E+  E++
Sbjct: 939  QEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEK 979



 Score = 36.2 bits (82), Expect = 0.34
 Identities = 21/103 (20%), Positives = 52/103 (50%), Gaps = 12/103 (11%)

Query: 1861 QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA 1920
            +++ AE RE+E+ K+ + + +  +EE      +E E  R++ E E+  +  E   +  + 
Sbjct: 809  RQLLAEKREQEEKKKQEEEEKKKREE------EERERERERREAELRAQQEEETRKQQEL 862

Query: 1921 DLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELED 1963
            +     ++  +L   +E + E+ + E+++       ++ E+ED
Sbjct: 863  EALQKSQKEAELTRELEKQKENKQVEEILR------LEKEIED 899


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  225 bits (574), Expect = 3e-58
 Identities = 267/1053 (25%), Positives = 446/1053 (42%), Gaps = 167/1053 (15%)

Query: 369  EELNLPEGKVRVKLDHDGAILDVDEDDVEKANAP------------SCDRLEDLASLVYL 416
            +E ++P G V VKL   G +  VD++D E   +P            S   +ED+  L  L
Sbjct: 18   QEFDVPIGAV-VKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDL 76

Query: 417  NESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYA 476
            NE+ +L  L  RY   L++TY G  L+ + P    ++YS + +  +   +  +M PHI+A
Sbjct: 77   NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFA 136

Query: 477  VAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALY 536
            +A   Y  M  + +DQ  I+ G SG+GKT S + ++Q+L   A ISG   +  ++     
Sbjct: 137  IADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFL---AAISGQHSWIEQQVLEAT 193

Query: 537  TLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFN 596
             +LEAFGN+ TI N N++RF + + + F++ G +  A I+  LLEK RV R+   E  ++
Sbjct: 194  PILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYH 253

Query: 597  VFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISP 656
            VFY +L       + +L L   ++ N   +      E +   +Q+++ +++AMKVL  + 
Sbjct: 254  VFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVD-SQEYANIRSAMKVLMFTD 312

Query: 657  DEQKACWFILAAIYHLG---AAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAI 713
             E      +LAAI HLG       T E  +A    F+       AA LL  +  +L S +
Sbjct: 313  TENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPS--LATAASLLEVNPPDLMSCL 370

Query: 714  FKHQ--HKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLV 771
                   +G T+    S  Q                AL+  +    G+Y  LF  +V  +
Sbjct: 371  TSRTLITRGETVSTPLSREQ----------------ALDVRDAFVKGIYGRLFVWIVDKI 414

Query: 772  NRAL-----KSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHER 826
            N A+     +  ++S  S+ ++D  GF+N          SFE+LC N+  + LQ+ F   
Sbjct: 415  NAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVN------SFEQLCINFANEHLQQFFVRH 468

Query: 827  TFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEE 886
             F  E E Y  E+I    D L     D+  A+D  +++ +            ++ L++EE
Sbjct: 469  VFKLEQEEYDLESI----DWLHIEFTDNQDALDMIANKPM-----------NIISLIDEE 513

Query: 887  ALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWL 946
            +  P  ++ T+L +L S +       K  +  +     H    G +H    V Y   G+L
Sbjct: 514  SKFPKGTDTTMLHKLNSQH-------KLNANYIPPKNNHETQFGINHFAGIVYYETQGFL 566

Query: 947  NYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMR 1006
                ++    +  +L+  S+ K I  +F                     Q  +      R
Sbjct: 567  E-KNRDTLHGDIIQLVHSSRNKFIKQIF---------------------QADVAMGAETR 604

Query: 1007 KTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRV 1066
            K         +  +L  Q K  ++ L+ T+   +  FV C  P                 
Sbjct: 605  K---------RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKP----------------- 638

Query: 1067 SSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFD 1126
               +E   P         +  D  L   QLR S +++ +R+ R GYP    F EF  R+ 
Sbjct: 639  ---NEFKKP---------MLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYR 686

Query: 1127 VLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDE 1186
            VL P +   + +     D R   + + E +        +G +++F +      LE +RD+
Sbjct: 687  VLLPGVKPAYKQG----DLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDK 742

Query: 1187 QTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKL-FTTVRP 1245
              +  + L Q   RG+  R +F K K    A   +Q++ + +   K++   +L F  ++ 
Sbjct: 743  AITDRVILLQKVIRGFKDRSNFLKLK---NAATLIQRHWRGHNCRKNYGLMRLGFLRLQA 799

Query: 1246 LIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTG 1305
            L   +   +Q R   + I Q +++  +A   R   R          + LT +        
Sbjct: 800  LHRSRKLHQQYRLARQRIIQFQARC-RAYLVRKAFR------HRLWAVLTVQAYARGMIA 852

Query: 1306 ESASQLLDAETAERLRAEK----EMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
                Q L AE   RL AEK    E ++L+ +  A KK  E  E +  E RL + A     
Sbjct: 853  RRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSA-KKAKEEAERKHQE-RLAQLAR---- 906

Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE 1394
               +DA  E  LK + A R     KK L ++ E
Sbjct: 907  ---EDA--ERELKEKEAARR----KKELLEQME 930



 Score = 34.7 bits (78), Expect = 0.98
 Identities = 37/111 (33%), Positives = 49/111 (44%), Gaps = 23/111 (20%)

Query: 1825 RELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTK 1884
            R L  RL  E   + RLE+   RL E  EKL +E   + A E  E++  +RL        
Sbjct: 853  RRLHQRLRAE--YLWRLEAEKMRLAEE-EKLRKEMSAKKAKEEAERKHQERL-------- 901

Query: 1885 EEMGELAR-------KEAEASRKKHEL--EMDLESLEAANQSLQADLKLAF 1926
                +LAR       KE EA+R+K EL  +M+    E  N S   D    F
Sbjct: 902  ---AQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGF 949



 Score = 32.0 bits (71), Expect = 6.3
 Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 7/81 (8%)

Query: 1568 LEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQM-EVQLEEEYEDKQKVL 1626
            LE  K+RL  E E++R    KEM ++  + EEA +  Q++L Q+     E E ++K+   
Sbjct: 867  LEAEKMRLAEE-EKLR----KEMSAKKAK-EEAERKHQERLAQLAREDAERELKEKEAAR 920

Query: 1627 REKRELEGKLATLSDQVNRRD 1647
            R+K  LE       + VN  D
Sbjct: 921  RKKELLEQMERARHEPVNHSD 941



 Score = 31.6 bits (70), Expect = 8.3
 Identities = 37/139 (26%), Positives = 64/139 (46%), Gaps = 15/139 (10%)

Query: 1433 QRLTAE----LQDTKLHLEGQQVRNHEL------EKKQRRFDSELSQ-AHEEAQREKLQR 1481
            QRL AE    L+  K+ L  ++    E+      E+ +R+    L+Q A E+A+RE  ++
Sbjct: 857  QRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEK 916

Query: 1482 EKLQREKDMLLAEAFSLKQQLEEKDM--DIAGFTQKVVSLEA-ELQDISSQESKDEASLA 1538
            E  +R+K++L     +  + +   DM   + GF      L   E Q  S  E  +     
Sbjct: 917  EAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRRE 976

Query: 1539 KVKKQLRDLEAKVKDQEEE 1557
             V++ L D    + D++EE
Sbjct: 977  MVEEDL-DAALPLPDEDEE 994


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  225 bits (574), Expect = 3e-58
 Identities = 267/1053 (25%), Positives = 446/1053 (42%), Gaps = 167/1053 (15%)

Query: 369  EELNLPEGKVRVKLDHDGAILDVDEDDVEKANAP------------SCDRLEDLASLVYL 416
            +E ++P G V VKL   G +  VD++D E   +P            S   +ED+  L  L
Sbjct: 18   QEFDVPIGAV-VKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDL 76

Query: 417  NESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYA 476
            NE+ +L  L  RY   L++TY G  L+ + P    ++YS + +  +   +  +M PHI+A
Sbjct: 77   NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFA 136

Query: 477  VAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALY 536
            +A   Y  M  + +DQ  I+ G SG+GKT S + ++Q+L   A ISG   +  ++     
Sbjct: 137  IADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFL---AAISGQHSWIEQQVLEAT 193

Query: 537  TLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFN 596
             +LEAFGN+ TI N N++RF + + + F++ G +  A I+  LLEK RV R+   E  ++
Sbjct: 194  PILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYH 253

Query: 597  VFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISP 656
            VFY +L       + +L L   ++ N   +      E +   +Q+++ +++AMKVL  + 
Sbjct: 254  VFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVD-SQEYANIRSAMKVLMFTD 312

Query: 657  DEQKACWFILAAIYHLG---AAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAI 713
             E      +LAAI HLG       T E  +A    F+       AA LL  +  +L S +
Sbjct: 313  TENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPS--LATAASLLEVNPPDLMSCL 370

Query: 714  FKHQ--HKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLV 771
                   +G T+    S  Q                AL+  +    G+Y  LF  +V  +
Sbjct: 371  TSRTLITRGETVSTPLSREQ----------------ALDVRDAFVKGIYGRLFVWIVDKI 414

Query: 772  NRAL-----KSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHER 826
            N A+     +  ++S  S+ ++D  GF+N          SFE+LC N+  + LQ+ F   
Sbjct: 415  NAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVN------SFEQLCINFANEHLQQFFVRH 468

Query: 827  TFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEE 886
             F  E E Y  E+I    D L     D+  A+D  +++ +            ++ L++EE
Sbjct: 469  VFKLEQEEYDLESI----DWLHIEFTDNQDALDMIANKPM-----------NIISLIDEE 513

Query: 887  ALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWL 946
            +  P  ++ T+L +L S +       K  +  +     H    G +H    V Y   G+L
Sbjct: 514  SKFPKGTDTTMLHKLNSQH-------KLNANYIPPKNNHETQFGINHFAGIVYYETQGFL 566

Query: 947  NYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMR 1006
                ++    +  +L+  S+ K I  +F                     Q  +      R
Sbjct: 567  E-KNRDTLHGDIIQLVHSSRNKFIKQIF---------------------QADVAMGAETR 604

Query: 1007 KTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRV 1066
            K         +  +L  Q K  ++ L+ T+   +  FV C  P                 
Sbjct: 605  K---------RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKP----------------- 638

Query: 1067 SSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFD 1126
               +E   P         +  D  L   QLR S +++ +R+ R GYP    F EF  R+ 
Sbjct: 639  ---NEFKKP---------MLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYR 686

Query: 1127 VLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDE 1186
            VL P +   + +     D R   + + E +        +G +++F +      LE +RD+
Sbjct: 687  VLLPGVKPAYKQG----DLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDK 742

Query: 1187 QTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKL-FTTVRP 1245
              +  + L Q   RG+  R +F K K    A   +Q++ + +   K++   +L F  ++ 
Sbjct: 743  AITDRVILLQKVIRGFKDRSNFLKLK---NAATLIQRHWRGHNCRKNYGLMRLGFLRLQA 799

Query: 1246 LIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTG 1305
            L   +   +Q R   + I Q +++  +A   R   R          + LT +        
Sbjct: 800  LHRSRKLHQQYRLARQRIIQFQARC-RAYLVRKAFR------HRLWAVLTVQAYARGMIA 852

Query: 1306 ESASQLLDAETAERLRAEK----EMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
                Q L AE   RL AEK    E ++L+ +  A KK  E  E +  E RL + A     
Sbjct: 853  RRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSA-KKAKEEAERKHQE-RLAQLAR---- 906

Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE 1394
               +DA  E  LK + A R     KK L ++ E
Sbjct: 907  ---EDA--ERELKEKEAARR----KKELLEQME 930



 Score = 34.7 bits (78), Expect = 0.98
 Identities = 37/111 (33%), Positives = 49/111 (44%), Gaps = 23/111 (20%)

Query: 1825 RELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTK 1884
            R L  RL  E   + RLE+   RL E  EKL +E   + A E  E++  +RL        
Sbjct: 853  RRLHQRLRAE--YLWRLEAEKMRLAEE-EKLRKEMSAKKAKEEAERKHQERL-------- 901

Query: 1885 EEMGELAR-------KEAEASRKKHEL--EMDLESLEAANQSLQADLKLAF 1926
                +LAR       KE EA+R+K EL  +M+    E  N S   D    F
Sbjct: 902  ---AQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGF 949



 Score = 32.0 bits (71), Expect = 6.3
 Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 7/81 (8%)

Query: 1568 LEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQM-EVQLEEEYEDKQKVL 1626
            LE  K+RL  E E++R    KEM ++  + EEA +  Q++L Q+     E E ++K+   
Sbjct: 867  LEAEKMRLAEE-EKLR----KEMSAKKAK-EEAERKHQERLAQLAREDAERELKEKEAAR 920

Query: 1627 REKRELEGKLATLSDQVNRRD 1647
            R+K  LE       + VN  D
Sbjct: 921  RKKELLEQMERARHEPVNHSD 941



 Score = 31.6 bits (70), Expect = 8.3
 Identities = 37/139 (26%), Positives = 64/139 (46%), Gaps = 15/139 (10%)

Query: 1433 QRLTAE----LQDTKLHLEGQQVRNHEL------EKKQRRFDSELSQ-AHEEAQREKLQR 1481
            QRL AE    L+  K+ L  ++    E+      E+ +R+    L+Q A E+A+RE  ++
Sbjct: 857  QRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEK 916

Query: 1482 EKLQREKDMLLAEAFSLKQQLEEKDM--DIAGFTQKVVSLEA-ELQDISSQESKDEASLA 1538
            E  +R+K++L     +  + +   DM   + GF      L   E Q  S  E  +     
Sbjct: 917  EAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRRE 976

Query: 1539 KVKKQLRDLEAKVKDQEEE 1557
             V++ L D    + D++EE
Sbjct: 977  MVEEDL-DAALPLPDEDEE 994


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.128    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,388,484
Number of Sequences: 37866
Number of extensions: 3530450
Number of successful extensions: 55306
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 855
Number of HSP's successfully gapped in prelim test: 1468
Number of HSP's that attempted gapping in prelim test: 16400
Number of HSP's gapped (non-prelim): 15156
length of query: 2039
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1921
effective length of database: 13,779,330
effective search space: 26470092930
effective search space used: 26470092930
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press