BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|126157508 N-acetylated alpha-linked acidic dipeptidase 2 [Homo sapiens] (795 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|126157508 N-acetylated alpha-linked acidic dipeptidase 2 [Hom... 1589 0.0 gi|4758398 folate hydrolase 1 isoform 1 [Homo sapiens] 212 1e-54 gi|4885505 N-acetylated alpha-linked acidic dipeptidase 2 [Homo ... 204 3e-52 gi|62548858 folate hydrolase 1 isoform 2 [Homo sapiens] 200 5e-51 gi|57232740 N-acetylated alpha-linked acidic dipeptidase-like 1 ... 178 2e-44 gi|33589848 transferrin receptor 2 [Homo sapiens] 149 1e-35 gi|24308545 folate hydrolase 1B [Homo sapiens] 135 2e-31 gi|189458819 transferrin receptor [Homo sapiens] 125 2e-28 gi|189458817 transferrin receptor [Homo sapiens] 125 2e-28 gi|239742769 PREDICTED: hypothetical protein XP_002342619 [Homo ... 31 3.9 gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 31 3.9 gi|31982906 cingulin-like 1 [Homo sapiens] 31 3.9 gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens] 31 5.2 gi|153792764 hypothetical protein LOC57624 [Homo sapiens] 31 5.2 gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens] 31 5.2 gi|56699485 ligatin [Homo sapiens] 31 5.2 gi|89276766 trophinin isoform 5 [Homo sapiens] 30 6.7 gi|29540551 trophinin isoform 2 [Homo sapiens] 30 6.7 gi|29540541 trophinin isoform 2 [Homo sapiens] 30 6.7 >gi|126157508 N-acetylated alpha-linked acidic dipeptidase 2 [Homo sapiens] Length = 795 Score = 1589 bits (4114), Expect = 0.0 Identities = 795/795 (100%), Positives = 795/795 (100%) Query: 1 MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESG 60 MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESG Sbjct: 1 MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESG 60 Query: 61 FDQFQLDGAENQNLGHSETIDLNLDSIQPATSPKGRFQRLQEESDYITHYTRSAPKSNRC 120 FDQFQLDGAENQNLGHSETIDLNLDSIQPATSPKGRFQRLQEESDYITHYTRSAPKSNRC Sbjct: 61 FDQFQLDGAENQNLGHSETIDLNLDSIQPATSPKGRFQRLQEESDYITHYTRSAPKSNRC 120 Query: 121 NFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS 180 NFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS Sbjct: 121 NFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKS 180 Query: 181 FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCF 240 FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCF Sbjct: 181 FRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCF 240 Query: 241 HPNGQPCSEEARKDSSQDLLYSYAAYSAKGTLKAEVIDVSYGMADDLKRIRKIKNVTNQI 300 HPNGQPCSEEARKDSSQDLLYSYAAYSAKGTLKAEVIDVSYGMADDLKRIRKIKNVTNQI Sbjct: 241 HPNGQPCSEEARKDSSQDLLYSYAAYSAKGTLKAEVIDVSYGMADDLKRIRKIKNVTNQI 300 Query: 301 ALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY 360 ALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY Sbjct: 301 ALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGY 360 Query: 361 PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQV 420 PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQV Sbjct: 361 PSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQV 420 Query: 421 QTVTKLKTVTNVVGFVMGLTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSK 480 QTVTKLKTVTNVVGFVMGLTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSK Sbjct: 421 QTVTKLKTVTNVVGFVMGLTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSK 480 Query: 481 VKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV 540 VKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV Sbjct: 481 VKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPV 540 Query: 541 ASPSLQQLVVEKNNFNCTRRAQCPETNISSIQIQGDADYFINHLGVPIVQFAYEDIKTLE 600 ASPSLQQLVVEKNNFNCTRRAQCPETNISSIQIQGDADYFINHLGVPIVQFAYEDIKTLE Sbjct: 541 ASPSLQQLVVEKNNFNCTRRAQCPETNISSIQIQGDADYFINHLGVPIVQFAYEDIKTLE 600 Query: 601 GPSFLSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQN 660 GPSFLSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQN Sbjct: 601 GPSFLSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQN 660 Query: 661 NLKGDQPNTHQLLAMALRLRESAELFQSDEMRPANDPKERAPIRIRMLNDILQDMEKSFL 720 NLKGDQPNTHQLLAMALRLRESAELFQSDEMRPANDPKERAPIRIRMLNDILQDMEKSFL Sbjct: 661 NLKGDQPNTHQLLAMALRLRESAELFQSDEMRPANDPKERAPIRIRMLNDILQDMEKSFL 720 Query: 721 VKQAPPGFYRNILYHLDEKTSRFSILIEAWEHCKPLASNETLQEALSEVLNSINSAQVYF 780 VKQAPPGFYRNILYHLDEKTSRFSILIEAWEHCKPLASNETLQEALSEVLNSINSAQVYF Sbjct: 721 VKQAPPGFYRNILYHLDEKTSRFSILIEAWEHCKPLASNETLQEALSEVLNSINSAQVYF 780 Query: 781 KAGLDVFKSVLDGKN 795 KAGLDVFKSVLDGKN Sbjct: 781 KAGLDVFKSVLDGKN 795 >gi|4758398 folate hydrolase 1 isoform 1 [Homo sapiens] Length = 750 Score = 212 bits (540), Expect = 1e-54 Identities = 185/702 (26%), Positives = 319/702 (45%), Gaps = 87/702 (12%) Query: 107 ITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQ 166 + H T SA + R L A F+ G L G+++ S ++ + Sbjct: 4 LLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIK----SSNEATNITPKHNMK 59 Query: 167 EILKTIQAEDIKKSFRNLVQ---LYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDL 223 L ++AE+IKK N Q L E + +++K+I++QW GL+ V+ +Y VLL Sbjct: 60 AFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSY 119 Query: 224 PG---PSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKGTLKAEVIDVS 280 P P+ ++ + F+ + ++ S D++ ++A+S +G + +++ V+ Sbjct: 120 PNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVS-DIVPPFSAFSPQGMPEGDLVYVN 178 Query: 281 YGMADD---LKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCD-LPK 336 Y +D L+R KI N + +I + + GK+ K+ + + AG GV+LY DP D Sbjct: 179 YARTEDFFKLERDMKI-NCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAP 237 Query: 337 TVNPSHDTF-----------MVSLNPGGDPSTPGYPSVDESFRQSRSN---LTSLLVQPI 382 V D + +++LN GDP TPGYP+ + ++R+ + L S+ V PI Sbjct: 238 GVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPI 297 Query: 383 SAPLVAKLISSPKARTKNEAC--SSLELPNN---------EIRVVSMQVQTVTKLKTVTN 431 KL+ ++ SL++P N + V M + + ++ + N Sbjct: 298 GYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYN 357 Query: 432 VVGFVMGLTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTI 491 V+G + G PDRY+I+G H + + G + S A++ +R+ + K GWRP RTI Sbjct: 358 VIGTLRGAVEPDRYVILGGHRDS-WVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTI 416 Query: 492 VFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPVASPSLQQLVVE 551 +F SW FG +GS EW E+ ++LQ+ VAYI+ S I GN +L +P + LV Sbjct: 417 LFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHN 476 Query: 552 KNN---------------FNCTRRAQCPE----TNISSIQIQGDADYFINHLGVPIVQFA 592 + T+++ PE IS + D + F LG+ + Sbjct: 477 LTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRAR 536 Query: 593 YEDIKTLEGPSF----LSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLP 648 Y K E F L + + T + DP F H T+ ++ G ++ ++AN VLP Sbjct: 537 Y--TKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLP 594 Query: 649 FNALD--------------IALEVQNNLKGDQPNTHQLLAMALRLRESAELFQSDEMRPA 694 F+ D I+++ +K + L + E A F S+ ++ Sbjct: 595 FDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKF-SERLQ-- 651 Query: 695 NDPKERAPIRIRMLNDILQDMEKSFLVKQAPPG--FYRNILY 734 D + PI +RM+ND L +E++F+ P FYR+++Y Sbjct: 652 -DFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIY 692 >gi|4885505 N-acetylated alpha-linked acidic dipeptidase 2 [Homo sapiens] Length = 740 Score = 204 bits (519), Expect = 3e-52 Identities = 174/682 (25%), Positives = 310/682 (45%), Gaps = 89/682 (13%) Query: 129 LCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIK---KSFRNLV 185 L A F+ G ++G+++ + +S + +++ ++AE+IK +SF L Sbjct: 14 LAAALASFLMGFMVGWFIKPL--KETTTSVRYHQSIRWKLVSEMKAENIKSFLRSFTKLP 71 Query: 186 QLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPS---TVTLSSSGQCFHP 242 L E + ++KKI+TQW GL+ + V+Y VLL P + + ++ + F Sbjct: 72 HLAGTEQNFLLAKKIQTQWKKFGLDSAKLVHYDVLLSYPNETNANYISIVDEHETEIFKT 131 Query: 243 NGQPCSEEARKDSSQDLLYSYAAYSAKGTLKAEVIDVSYGMADDLKRIRKIK--NVTNQI 300 + + ++ + +++ Y A+SA+G + +++ V+Y +D ++ + N T +I Sbjct: 132 SYLEPPPDGYENVT-NIVPPYNAFSAQGMPEGDLVYVNYARTEDFFKLEREMGINCTGKI 190 Query: 301 ALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDL--------PKTVN----PSHDTFMVS 348 + + GK+ K+ + AG G++LY DP D PK N + +++ Sbjct: 191 VIARYGKIFRGNKVKNAMLAGAIGIILYSDPADYFAPEVQPYPKGWNLPGTAAQRGNVLN 250 Query: 349 LNPGGDPSTPGYPSVDESFR---QSRSNLTSLLVQPIS---APLVAKL---ISSPKARTK 399 LN GDP TPGYP+ + +FR + + + V PI A ++ + I+ P K Sbjct: 251 LNGAGDPLTPGYPAKEYTFRLDVEEGVGIPRIPVHPIGYNDAEILLRYLGGIAPPDKSWK 310 Query: 400 NEACSSLELP-----NNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGSHHHT 454 S + ++ R V M V + K+ + NVVG + G PDRY+I+G H + Sbjct: 311 GALNVSYSIGPGFTGSDSFRKVRMHVYNINKITRIYNVVGTIRGSVEPDRYVILGGHRDS 370 Query: 455 AHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFK 514 + + S A++ R+ + +GWRP RTI+F SW FG +GS EW E+ Sbjct: 371 -WVFGAIDPTSGVAVLQEIARSFGKLMSKGWRPRRTIIFASWDAEEFGLLGSTEWAEENV 429 Query: 515 KVLQKNVVAYISLHSPIRGNSSLYPVASPSLQQLVVEKNNFNCTRRAQCPETNISSIQIQ 574 K+LQ+ +AYI+ S I GN +L +P L QLV + T+ P+ S + Sbjct: 430 KILQERSIAYINSDSSIEGNYTLRVDCTPLLYQLV-----YKLTKEIPSPDDGFESKSLY 484 Query: 575 ------------------------GDADYFINHLGVPIVQFAY-EDIKTLEGPSF-LSEA 608 D + + LG+ + Y ++ KT + S+ + Sbjct: 485 ESWLEKDPSPENKNLPRINKLGSGSDFEAYFQRLGIASGRARYTKNKKTDKYSSYPVYHT 544 Query: 609 RFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQN-------- 660 + T + DP+F ++ +L G ++ ++ + ++PFN D A ++N Sbjct: 545 IYETFELVEKFYDPTFKKQLSVAQLRGALVYELVDSKIIPFNIQDYAEALKNYAASIYNL 604 Query: 661 NLKGDQPNT------HQLLAMALRLRESAELFQSDEMRPANDPKERAPIRIRMLNDILQD 714 + K DQ T L + E+A SD + PI +RM+ND L Sbjct: 605 SKKHDQQLTDHGVSFDSLFSAVKNFSEAA----SDFHKRLIQVDLNNPIAVRMMNDQLML 660 Query: 715 MEKSFLVKQAPPG--FYRNILY 734 +E++F+ PG FYR+I++ Sbjct: 661 LERAFIDPLGLPGKLFYRHIIF 682 >gi|62548858 folate hydrolase 1 isoform 2 [Homo sapiens] Length = 719 Score = 200 bits (508), Expect = 5e-51 Identities = 164/608 (26%), Positives = 280/608 (46%), Gaps = 67/608 (11%) Query: 107 ITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQ 166 + H T SA + R L A F+ G L G+++ S ++ + Sbjct: 4 LLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIK----SSNEATNITPKHNMK 59 Query: 167 EILKTIQAEDIKKSFRNLVQ---LYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDL 223 L ++AE+IKK N Q L E + +++K+I++QW GL+ V+ +Y VLL Sbjct: 60 AFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSY 119 Query: 224 PG---PSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKGTLKAEVIDVS 280 P P+ ++ + F+ + ++ S D++ ++A+S +G + +++ V+ Sbjct: 120 PNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVS-DIVPPFSAFSPQGMPEGDLVYVN 178 Query: 281 YGMADD---LKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCD-LPK 336 Y +D L+R KI N + +I + + GK+ K+ + + AG GV+LY DP D Sbjct: 179 YARTEDFFKLERDMKI-NCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAP 237 Query: 337 TVNPSHDTF-----------MVSLNPGGDPSTPGYPSVDESFRQSRSN---LTSLLVQPI 382 V D + +++LN GDP TPGYP+ + ++R+ + L S+ V PI Sbjct: 238 GVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPI 297 Query: 383 SAPLVAKLISSPKARTKNEAC--SSLELPNN---------EIRVVSMQVQTVTKLKTVTN 431 KL+ ++ SL++P N + V M + + ++ + N Sbjct: 298 GYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYN 357 Query: 432 VVGFVMGLTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTI 491 V+G + G PDRY+I+G H + + G + S A++ +R+ + K GWRP RTI Sbjct: 358 VIGTLRGAVEPDRYVILGGHRDS-WVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTI 416 Query: 492 VFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPVASPSLQQLVVE 551 +F SW FG +GS EW E+ ++LQ+ VAYI+ S I GN +L +P + LV Sbjct: 417 LFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHN 476 Query: 552 KNN---------------FNCTRRAQCPE----TNISSIQIQGDADYFINHLGVPIVQFA 592 + T+++ PE IS + D + F LG+ + Sbjct: 477 LTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRAR 536 Query: 593 YEDIKTLEGPSF----LSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLP 648 Y K E F L + + T + DP F H T+ ++ G ++ ++AN VLP Sbjct: 537 Y--TKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLP 594 Query: 649 FNALDIAL 656 F+ D A+ Sbjct: 595 FDCRDYAV 602 >gi|57232740 N-acetylated alpha-linked acidic dipeptidase-like 1 [Homo sapiens] Length = 740 Score = 178 bits (452), Expect = 2e-44 Identities = 177/690 (25%), Positives = 307/690 (44%), Gaps = 92/690 (13%) Query: 125 VLKILCTATILFIFGILIGYY-VHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKSFRN 183 VL + A L GI++G++ + S AP +D ++ + ++ + A I+++ R Sbjct: 6 VLGLGLGAAALLGLGIILGHFAIPKKANSLAPQD--LDLEILETVMGQLDAHRIRENLRE 63 Query: 184 LVQ---LYKNEDDMEISKKIKTQWTS--LGLEDVQFVNYSVLLDLPGPSPSTVT--LSSS 236 L + L + D ++ + + +W GL+ + Y VLL P V + + Sbjct: 64 LSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIVGPT 123 Query: 237 GQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKGTLKAEVIDVSYGMADDLKRIRK--IK 294 G H + + D++ YAAY+ GT + ++ + G +D K ++ IK Sbjct: 124 GGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQGIK 183 Query: 295 NVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVS--LNPG 352 + IAL + G + K + K G GVL+Y DP D+ ++ +TF S L P Sbjct: 184 -LEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLPPS 242 Query: 353 G-----------DPSTPGYPSVDESFRQSRSNLTS---LLVQPI----SAPLVAKLISSP 394 G DP TP P+V SFR +N++ + QPI + L+ L + Sbjct: 243 GVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNGTL 302 Query: 395 KARTKNEACSSLEL------PNNEIRV---VSMQVQTVTKLKTVTNVVGFVMGLTSPDRY 445 T A P+ + V++ V +L+ +NV+G + G PDRY Sbjct: 303 APATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPDRY 362 Query: 446 IIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSKVKRG-WRPDRTIVFCSWGGTAFGNI 504 ++ G+H + + + +S TA++ R L + +K+G WRP R+IVF SWG FG I Sbjct: 363 VLYGNHRDS-WVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGLI 421 Query: 505 GSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPVASPSLQQLVVEKNNFNCTRRAQCP 564 GS E+ E+F LQ+ VAYI++ + N++L +P +Q +V F+ T+ + P Sbjct: 422 GSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVV-----FSATKEIRSP 476 Query: 565 ETNISSI----------------------QIQGDADY--FINHLGVPI--VQFAYEDIKT 598 SI + +DY F++ LG+ + + Y+ KT Sbjct: 477 GPGDLSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKT 536 Query: 599 LEGPSFLSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLPFNALDIALEV 658 F T + +DP F+ H+ + + +G VIL++++ LP D + + Sbjct: 537 SARIYPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETL 596 Query: 659 QNNLKGDQPNTHQLL------------AMALRLRESAELFQSDEMRPANDPKERAPIRIR 706 ++ L+ Q + LL A+ E+A L Q P P+++R Sbjct: 597 RSFLQAAQQDLGALLEQHSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPD---PLQVR 653 Query: 707 MLNDILQDMEKSFLVKQAPP--GFYRNILY 734 MLND L +E++FL +A P +Y ++L+ Sbjct: 654 MLNDQLMLLERTFLNPRAFPEERYYSHVLW 683 >gi|33589848 transferrin receptor 2 [Homo sapiens] Length = 801 Score = 149 bits (376), Expect = 1e-35 Identities = 118/442 (26%), Positives = 206/442 (46%), Gaps = 38/442 (8%) Query: 241 HPNGQPCSEEARKDSSQDLLYS---YAAYSAKGTLKAEVIDVSYGMADDLKRIR-KIKNV 296 HPN +EA K Q L Y YSA G + E++ YG +DL+ +R + + Sbjct: 207 HPNTLHWVDEAGKVGEQLPLEDPDVYCPYSAIGNVTGELVYAHYGRPEDLQDLRARGVDP 266 Query: 297 TNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDL----PKTVNPSHDTFMVSLNPG 352 ++ L+++G + K+++ + G GVL+Y +P D PK S ++ G Sbjct: 267 VGRLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEPADFSQDPPKPSLSSQQAVYGHVHLG 326 Query: 353 -GDPSTPGYPSVDESFRQ--SRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLEL- 408 GDP TPG+PS +++ + S L S+ QPISA + ++L+ K + L Sbjct: 327 TGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASRLLRKLKGPVAPQEWQGSLLG 386 Query: 409 ------PNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGSHHHTAHSYNGQE 462 P +R+V +T T + N+ G + G + PD Y+++G+ A + Sbjct: 387 SPYHLGPGPRLRLVVNNHRTSTP---INNIFGCIEGRSEPDHYVVIGAQRD-AWGPGAAK 442 Query: 463 WASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVV 522 A TAI+ +R S V G+RP R+++F SW G FG++GS EW E + VL V Sbjct: 443 SAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAV 502 Query: 523 AYISLHSPIRGNSSLYPVASPSLQQL-------VVEKNNFNCTRRAQCPETN-------I 568 Y+SL + + G+ + SP L L V N+ T Q TN I Sbjct: 503 VYVSLDNAVLGDDKFHAKTSPLLTSLIESVLKQVDSPNHSGQTLYEQVVFTNPSWDAEVI 562 Query: 569 SSIQIQGDADYFINHLGVPIVQFAYEDIKTLEGPSFLSEARFSTRATKIEEMDPSFNLHE 628 + + A F +GVP V+F++ + E + ++ P+ + + Sbjct: 563 RPLPMDSSAYSFTAFVGVPAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPA--VAQ 620 Query: 629 TITKLSGEVILQIANEPVLPFN 650 + +L+G+++++++++ +LP + Sbjct: 621 AVAQLAGQLLIRLSHDRLLPLD 642 >gi|24308545 folate hydrolase 1B [Homo sapiens] Length = 442 Score = 135 bits (339), Expect = 2e-31 Identities = 99/366 (27%), Positives = 166/366 (45%), Gaps = 50/366 (13%) Query: 410 NNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGSHHHTAHSYNGQEWASSTAI 469 N + V M + + ++ + NV+G + G PDRY+I+G H + + G + S A+ Sbjct: 28 NFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDS-WVFGGIDPQSGAAV 86 Query: 470 ITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHS 529 + +R+ + K GWRP RTI+F SW FG +GS EW ED ++LQ+ VAYI+ S Sbjct: 87 VHETVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEDNSRLLQERGVAYINADS 146 Query: 530 PIRGNSSLYPVASPSLQQLVVEKNNFNCTRRAQCPE------------------------ 565 I GN +L +P + LV +N T+ + P+ Sbjct: 147 SIEGNYTLRVDCTPLMYSLV-----YNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGM 201 Query: 566 TNISSIQIQGDADYFINHLGVPIVQFAYEDIKTLEGPSF----LSEARFSTRATKIEEMD 621 IS + D + F LG+ + Y K E F L + + T + D Sbjct: 202 PRISKLGSGNDFEVFFQRLGIASGRARY--TKNWETNKFSGYPLYHSVYETYELVEKFYD 259 Query: 622 PSFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQN------NLKGDQPNTHQLLAM 675 P F H T+ ++ G ++ ++AN VLPF+ D A+ ++ N+ P + ++ Sbjct: 260 PMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYNISMKHPQEMKTYSL 319 Query: 676 AL-----RLRESAELFQSDEMRPANDPKERAPIRIRMLNDILQDMEKSFLVKQAPPG--F 728 + ++ E+ R D + PI +RM+ND L +E++F+ P F Sbjct: 320 SFDSLFSAVKNFTEIASKFSER-LQDFDKSNPILLRMMNDQLMFLERAFIDPLGLPDRPF 378 Query: 729 YRNILY 734 YR+++Y Sbjct: 379 YRHVIY 384 >gi|189458819 transferrin receptor [Homo sapiens] Length = 760 Score = 125 bits (313), Expect = 2e-28 Identities = 95/344 (27%), Positives = 160/344 (46%), Gaps = 18/344 (5%) Query: 263 YAAYSAKGTLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGF 322 Y AYS T+ +++ ++G D + + V I +++ GK+ K+++ E Sbjct: 219 YVAYSKAATVTGKLVHANFGTKKDFEDL--YTPVNGSIVIVRAGKITFAEKVANAESLNA 276 Query: 323 GGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGYPSVDES-FRQSRSN-LTSLLVQ 380 GVL+Y+D P VN F + GDP TPG+PS + + F SRS+ L ++ VQ Sbjct: 277 IGVLIYMDQTKFP-IVNAELSFFGHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQ 335 Query: 381 PISAPLVAKLISSPKARTKNE--ACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMG 438 IS KL + + ++ S+ + +E + V + V V K + N+ G + G Sbjct: 336 TISRAAAEKLFGNMEGDCPSDWKTDSTCRMVTSESKNVKLTVSNVLKEIKILNIFGVIKG 395 Query: 439 LTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSKV-KRGWRPDRTIVFCSWG 497 PD Y++VG+ A + TA++ + V K G++P R+I+F SW Sbjct: 396 FVEPDHYVVVGAQRD-AWGPGAAKSGVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWS 454 Query: 498 GTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPVASPSLQQLVVEKNNFN- 556 FG++G+ EW E + L YI+L + G S+ ASP L L +EK N Sbjct: 455 AGDFGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTL-IEKTMQNV 513 Query: 557 ---CTRRAQCPETN----ISSIQIQGDADYFINHLGVPIVQFAY 593 T + ++N + + + A F+ + G+P V F + Sbjct: 514 KHPVTGQFLYQDSNWASKVEKLTLDNAAFPFLAYSGIPAVSFCF 557 >gi|189458817 transferrin receptor [Homo sapiens] Length = 760 Score = 125 bits (313), Expect = 2e-28 Identities = 95/344 (27%), Positives = 160/344 (46%), Gaps = 18/344 (5%) Query: 263 YAAYSAKGTLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGF 322 Y AYS T+ +++ ++G D + + V I +++ GK+ K+++ E Sbjct: 219 YVAYSKAATVTGKLVHANFGTKKDFEDL--YTPVNGSIVIVRAGKITFAEKVANAESLNA 276 Query: 323 GGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGYPSVDES-FRQSRSN-LTSLLVQ 380 GVL+Y+D P VN F + GDP TPG+PS + + F SRS+ L ++ VQ Sbjct: 277 IGVLIYMDQTKFP-IVNAELSFFGHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQ 335 Query: 381 PISAPLVAKLISSPKARTKNE--ACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMG 438 IS KL + + ++ S+ + +E + V + V V K + N+ G + G Sbjct: 336 TISRAAAEKLFGNMEGDCPSDWKTDSTCRMVTSESKNVKLTVSNVLKEIKILNIFGVIKG 395 Query: 439 LTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSKV-KRGWRPDRTIVFCSWG 497 PD Y++VG+ A + TA++ + V K G++P R+I+F SW Sbjct: 396 FVEPDHYVVVGAQRD-AWGPGAAKSGVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWS 454 Query: 498 GTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPVASPSLQQLVVEKNNFN- 556 FG++G+ EW E + L YI+L + G S+ ASP L L +EK N Sbjct: 455 AGDFGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTL-IEKTMQNV 513 Query: 557 ---CTRRAQCPETN----ISSIQIQGDADYFINHLGVPIVQFAY 593 T + ++N + + + A F+ + G+P V F + Sbjct: 514 KHPVTGQFLYQDSNWASKVEKLTLDNAAFPFLAYSGIPAVSFCF 557 >gi|239742769 PREDICTED: hypothetical protein XP_002342619 [Homo sapiens] Length = 351 Score = 31.2 bits (69), Expect = 3.9 Identities = 18/86 (20%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Query: 186 QLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQ 245 Q + N+D+ +S+ + +W +LG ++Q N + + + + GQ P Sbjct: 112 QGHPNQDNRTVSQMLSERWYTLGPNEMQKYNLAFQVKVAHLQQGPKEVQLRGQAHKPG-- 169 Query: 246 PCSEEARKDSSQDLLYSYAAYSAKGT 271 + + D+ + LL+ A ++GT Sbjct: 170 --ASRSSSDTKEQLLWGRTAAHSQGT 193 >gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] Length = 4374 Score = 31.2 bits (69), Expect = 3.9 Identities = 28/113 (24%), Positives = 45/113 (39%), Gaps = 3/113 (2%) Query: 1 MGENEASLPNTS-LQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEES 59 M E ++L S LQ + + + H+Q D+ D + + E+E E+ Sbjct: 2383 MDEAPSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDE 2442 Query: 60 GFDQFQLDGAENQNLGHSETIDLNLDSIQPA--TSPKGRFQRLQEESDYITHY 110 DQ +G E + ++ LD P SP RF+R E D I + Sbjct: 2443 EDDQEDDEGEEGDEDDDDDGSEMELDEDYPDMNASPLVRFERFDREDDLIIEF 2495 >gi|31982906 cingulin-like 1 [Homo sapiens] Length = 1302 Score = 31.2 bits (69), Expect = 3.9 Identities = 38/182 (20%), Positives = 78/182 (42%), Gaps = 18/182 (9%) Query: 606 SEARFSTRATKIEEMDPSFNLHETITKLSGEV--ILQIANEPVLPF-NALDI-------- 654 SE + R K E + ++L +TI KL E+ I++ + L N LD Sbjct: 926 SEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRE 985 Query: 655 ALEVQNNLKGDQPNTHQLLAMALRLRESAELFQSDEMRPANDPKERAPIRIRMLNDILQD 714 E+Q LK + A+++++ L + +E+R ++ A + ++L L+D Sbjct: 986 LAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLME-EELRDYQRAQDEALTKRQLLEQTLKD 1044 Query: 715 MEKSFLVKQAPPGFYRNILYHLDEKTSRFSILIEAWEHCKPL------ASNETLQEALSE 768 +E K ++ +++K S+ + +E + L S E +++ +E Sbjct: 1045 LEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNE 1104 Query: 769 VL 770 +L Sbjct: 1105 LL 1106 >gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens] Length = 828 Score = 30.8 bits (68), Expect = 5.2 Identities = 38/147 (25%), Positives = 64/147 (43%), Gaps = 26/147 (17%) Query: 617 IEEMDPSFN-LHETITKLSGEVILQIANEPVLPFNALDIALEVQNNLKGDQPNTHQLLAM 675 IE D FN L + K G I+ A + P E+Q NL N +++L Sbjct: 309 IELNDQKFNELIKNCNKHDGRGIIVDARQLPSPEPC-----EIQKNL-----NDNEMLFH 358 Query: 676 ALRLRESAELFQSDEMRPANDPKERAPIRIRMLNDILQDMEKSFLVKQAPPGFYRNILYH 735 + ++ E E + +E++P I + +I+Q+ EK QA P F+ Sbjct: 359 SCQMVE--ESHEEEELKPPEQ-------EIEIDRNIIQEEEK-----QAIPEFFEGRQAK 404 Query: 736 LDEKTSRF-SILIEAWEHCKPLASNET 761 E+ + + +++ WE CKP N+T Sbjct: 405 TPERYLKIRNYILDQWEICKPKYLNKT 431 >gi|153792764 hypothetical protein LOC57624 [Homo sapiens] Length = 653 Score = 30.8 bits (68), Expect = 5.2 Identities = 12/25 (48%), Positives = 17/25 (68%) Query: 693 PANDPKERAPIRIRMLNDILQDMEK 717 PA DP+E P+ I M+ +IL+D K Sbjct: 234 PAGDPEEEEPVYIEMVGNILRDFRK 258 >gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens] Length = 669 Score = 30.8 bits (68), Expect = 5.2 Identities = 12/25 (48%), Positives = 17/25 (68%) Query: 693 PANDPKERAPIRIRMLNDILQDMEK 717 PA DP+E P+ I M+ +IL+D K Sbjct: 234 PAGDPEEEEPVYIEMVGNILRDFRK 258 >gi|56699485 ligatin [Homo sapiens] Length = 584 Score = 30.8 bits (68), Expect = 5.2 Identities = 44/184 (23%), Positives = 73/184 (39%), Gaps = 32/184 (17%) Query: 66 LDGAENQNLGHSETIDLNLDSIQPATSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHV 125 L+G E H D +L TS +G Q + +D T + +C F H Sbjct: 220 LEGEEENGEVHQAREDKSLSEAPEDTSTRGLNQ---DSTDSKTLQEQMDELLQQC-FLHA 275 Query: 126 LKI-LCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKSFRNL 184 LK + A + + +G ++ + CP QL DIKKS + Sbjct: 276 LKCRVKKADLPLLTSTFLGSHMFSCCPEGR--------QL-----------DIKKS--SY 314 Query: 185 VQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNY------SVLLDLPGPSPSTVTLSSSGQ 238 +L K M+ + I+ + S G+E + V++ S ++ P P+ T+ S Q Sbjct: 315 KKLSKFLQQMQQEQIIQVKELSKGVESIVAVDWKHPRITSFVIPEPSPTSQTIQEGSREQ 374 Query: 239 CFHP 242 +HP Sbjct: 375 PYHP 378 >gi|89276766 trophinin isoform 5 [Homo sapiens] Length = 1431 Score = 30.4 bits (67), Expect = 6.7 Identities = 31/140 (22%), Positives = 58/140 (41%), Gaps = 24/140 (17%) Query: 355 PSTPGYPSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIR 414 P+ P P+ +E +N + Q ++ P++ ++ ++A + E+ N + Sbjct: 84 PAAPPVPAANEI----ATNKPKITWQALNLPVITQI---------SQALPTTEVTNTQAS 130 Query: 415 VVSMQVQTVTKLKTVTNVV-----------GFVMGLTSPDRYIIVGSHHHTAHSYNGQEW 463 V+ Q + K+K VT G + L SP + + + H+ E Sbjct: 131 SVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNIHAPIANES 190 Query: 464 ASSTAIITAFIRALMSKVKR 483 ASS A+IT+ SK K+ Sbjct: 191 ASSQALITSIKPKKASKAKK 210 >gi|29540551 trophinin isoform 2 [Homo sapiens] Length = 706 Score = 30.4 bits (67), Expect = 6.7 Identities = 31/140 (22%), Positives = 58/140 (41%), Gaps = 24/140 (17%) Query: 355 PSTPGYPSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIR 414 P+ P P+ +E +N + Q ++ P++ ++ ++A + E+ N + Sbjct: 84 PAAPPVPAANEI----ATNKPKITWQALNLPVITQI---------SQALPTTEVTNTQAS 130 Query: 415 VVSMQVQTVTKLKTVTNVV-----------GFVMGLTSPDRYIIVGSHHHTAHSYNGQEW 463 V+ Q + K+K VT G + L SP + + + H+ E Sbjct: 131 SVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNIHAPIANES 190 Query: 464 ASSTAIITAFIRALMSKVKR 483 ASS A+IT+ SK K+ Sbjct: 191 ASSQALITSIKPKKASKAKK 210 >gi|29540541 trophinin isoform 2 [Homo sapiens] Length = 706 Score = 30.4 bits (67), Expect = 6.7 Identities = 31/140 (22%), Positives = 58/140 (41%), Gaps = 24/140 (17%) Query: 355 PSTPGYPSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIR 414 P+ P P+ +E +N + Q ++ P++ ++ ++A + E+ N + Sbjct: 84 PAAPPVPAANEI----ATNKPKITWQALNLPVITQI---------SQALPTTEVTNTQAS 130 Query: 415 VVSMQVQTVTKLKTVTNVV-----------GFVMGLTSPDRYIIVGSHHHTAHSYNGQEW 463 V+ Q + K+K VT G + L SP + + + H+ E Sbjct: 131 SVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNIHAPIANES 190 Query: 464 ASSTAIITAFIRALMSKVKR 483 ASS A+IT+ SK K+ Sbjct: 191 ASSQALITSIKPKKASKAKK 210 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,775,440 Number of Sequences: 37866 Number of extensions: 1339334 Number of successful extensions: 3753 Number of sequences better than 10.0: 19 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 3700 Number of HSP's gapped (non-prelim): 21 length of query: 795 length of database: 18,247,518 effective HSP length: 110 effective length of query: 685 effective length of database: 14,082,258 effective search space: 9646346730 effective search space used: 9646346730 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.