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Search of human proteins with 42544174
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42544174 deoxythymidylate kinase (thymidylate kinase) [Homo
sapiens]
(212 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42544174 deoxythymidylate kinase (thymidylate kinase) [Homo s... 422 e-119
gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens] 31 0.89
gi|4502013 adenylate kinase 2 isoform a [Homo sapiens] 31 0.89
gi|7524346 adenylate kinase 2 isoform b [Homo sapiens] 31 0.89
gi|73808268 matrix metalloproteinase 27 [Homo sapiens] 30 1.5
gi|67551265 transcription factor ELYS [Homo sapiens] 29 2.6
gi|54792098 erbB-2 isoform b [Homo sapiens] 28 4.4
gi|54792096 erbB-2 isoform a [Homo sapiens] 28 4.4
gi|57163987 solute carrier family 8 member 2 [Homo sapiens] 28 4.4
gi|169162524 PREDICTED: hypothetical protein [Homo sapiens] 28 5.7
gi|113412620 PREDICTED: hypothetical protein [Homo sapiens] 28 5.7
gi|113411677 PREDICTED: hypothetical protein [Homo sapiens] 28 5.7
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein... 28 5.7
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ... 28 5.7
gi|154426306 kinesin family member 24 [Homo sapiens] 28 5.7
gi|19923979 ADP-ribosylation factor-like 11 [Homo sapiens] 28 7.5
gi|207452735 epiplakin 1 [Homo sapiens] 28 7.5
gi|45593142 kelch repeat and BTB (POZ) domain containing 5 [Homo... 28 7.5
gi|68160947 secretogranin II precursor [Homo sapiens] 27 9.8
gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 ... 27 9.8
gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 K... 27 9.8
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens] 27 9.8
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 27 9.8
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 27 9.8
>gi|42544174 deoxythymidylate kinase (thymidylate kinase) [Homo
sapiens]
Length = 212
Score = 422 bits (1086), Expect = e-119
Identities = 212/212 (100%), Positives = 212/212 (100%)
Query: 1 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK 60
MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
Sbjct: 1 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK 60
Query: 61 SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQP 120
SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQP
Sbjct: 61 SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQP 120
Query: 121 DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA 180
DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA
Sbjct: 121 DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA 180
Query: 181 SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK 212
SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK
Sbjct: 181 SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK 212
>gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens]
Length = 228
Score = 30.8 bits (68), Expect = 0.89
Identities = 45/197 (22%), Positives = 83/197 (42%), Gaps = 26/197 (13%)
Query: 8 LIVLEGVDRAGKSTQSRKLVEALCAAGHRA-ELLRFPERS--TEIGKLLSSYLQKKSDVE 64
++ + G AGK TQ ++VE A ELLR ++ ++ G+L+ Y+++ V
Sbjct: 37 VVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVP 96
Query: 65 DHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQPDVGL 124
V + S L+K ++ Q + + F F ++N W K D G
Sbjct: 97 ---VEITIS--------LLKREMDQTMAANAQKNKFLIDGFPRNQDNLQ-GWNKTMD-GK 143
Query: 125 PKPDLVLFL----QLQLADAAKRGAFGHERYENGAFQERALRCFHQLMK------DTTLN 174
VLF ++ + +RG +N E+ ++ + Q K +
Sbjct: 144 ADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGK 203
Query: 175 WKMVDASKSIEAVHEDI 191
K +DASKS++ V +++
Sbjct: 204 VKKIDASKSVDEVFDEV 220
>gi|4502013 adenylate kinase 2 isoform a [Homo sapiens]
Length = 239
Score = 30.8 bits (68), Expect = 0.89
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 5 RGALIVLEGVDRAGKSTQSRKLVEALCAAGHRA--ELLRFPERS-TEIGKLLSSYLQKKS 61
+G VL G AGK TQ+ +L E C H A ++LR S +E+GK L + +
Sbjct: 14 KGIRAVLLGPPGAGKGTQAPRLAENFCVC-HLATGDMLRAMVASGSELGKKLKATMDAGK 72
Query: 62 DVEDHSVHLLFSANRWEQVPLIK 84
V D V L N + PL K
Sbjct: 73 LVSDEMVVELIEKNL--ETPLCK 93
>gi|7524346 adenylate kinase 2 isoform b [Homo sapiens]
Length = 232
Score = 30.8 bits (68), Expect = 0.89
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 5 RGALIVLEGVDRAGKSTQSRKLVEALCAAGHRA--ELLRFPERS-TEIGKLLSSYLQKKS 61
+G VL G AGK TQ+ +L E C H A ++LR S +E+GK L + +
Sbjct: 14 KGIRAVLLGPPGAGKGTQAPRLAENFCVC-HLATGDMLRAMVASGSELGKKLKATMDAGK 72
Query: 62 DVEDHSVHLLFSANRWEQVPLIK 84
V D V L N + PL K
Sbjct: 73 LVSDEMVVELIEKNL--ETPLCK 93
>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
Length = 513
Score = 30.0 bits (66), Expect = 1.5
Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 12/87 (13%)
Query: 39 LLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRY 98
L+R E + +L +YL + +E HL+ S NR LI +K+ +
Sbjct: 20 LVRMTENEENM-QLAQAYLNQFYSLEIEGNHLVQSKNR----SLIDDKIRE-------MQ 67
Query: 99 AFSGVAFTGAKENFSLDWCKQPDVGLP 125
AF G+ TG ++ +L+ K P G+P
Sbjct: 68 AFFGLTVTGKLDSNTLEIMKTPRCGVP 94
>gi|67551265 transcription factor ELYS [Homo sapiens]
Length = 2266
Score = 29.3 bits (64), Expect = 2.6
Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 24 RKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSANRWEQVPLI 83
+ + E G +LL+ P TE + L +LQ + V++H L+ R VP +
Sbjct: 910 KHMYEVCQEMGLMEDLLKLPFTDTE-QECLVKFLQSSASVQNHEFLLVHHLQRANYVPAL 968
Query: 84 KEKLSQGVTLVVDR 97
K + + ++ DR
Sbjct: 969 KLNQTLKINVMNDR 982
>gi|54792098 erbB-2 isoform b [Homo sapiens]
Length = 1225
Score = 28.5 bits (62), Expect = 4.4
Identities = 15/47 (31%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
Query: 55 SYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFS 101
S+LQ D+++ ++L + N+ QVPL + ++ +G L D YA +
Sbjct: 42 SFLQ---DIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALA 85
>gi|54792096 erbB-2 isoform a [Homo sapiens]
Length = 1255
Score = 28.5 bits (62), Expect = 4.4
Identities = 15/47 (31%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
Query: 55 SYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFS 101
S+LQ D+++ ++L + N+ QVPL + ++ +G L D YA +
Sbjct: 72 SFLQ---DIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALA 115
>gi|57163987 solute carrier family 8 member 2 [Homo sapiens]
Length = 921
Score = 28.5 bits (62), Expect = 4.4
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 5/73 (6%)
Query: 113 SLDWCKQPDVGLPKPDLVLFL-----QLQLADAAKRGAFGHERYENGAFQERALRCFHQL 167
S D+ D + K +L L + + Q +A A E E+G+ +ER CF +
Sbjct: 666 SYDFKNTVDKLIKKTNLALVIGTHSWREQFLEAITVSAGDEEEEEDGSREERLPSCFDYV 725
Query: 168 MKDTTLNWKMVDA 180
M T+ WK++ A
Sbjct: 726 MHFLTVFWKVLFA 738
>gi|169162524 PREDICTED: hypothetical protein [Homo sapiens]
Length = 109
Score = 28.1 bits (61), Expect = 5.7
Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 34 GHRAELLRFPERSTEIGKLLSSYLQKKSDV--EDHSVHLLFSANRWEQVPLIKEK 86
G EL FPERSTE K+ +K++ ED++ HL+ S V + EK
Sbjct: 42 GFSEELQYFPERSTEKLKVFEWEEEKQTTATSEDNTKHLVHSVYTRGAVNFLVEK 96
>gi|113412620 PREDICTED: hypothetical protein [Homo sapiens]
Length = 109
Score = 28.1 bits (61), Expect = 5.7
Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 34 GHRAELLRFPERSTEIGKLLSSYLQKKSDV--EDHSVHLLFSANRWEQVPLIKEK 86
G EL FPERSTE K+ +K++ ED++ HL+ S V + EK
Sbjct: 42 GFSEELQYFPERSTEKLKVFEWEEEKQTTATSEDNTKHLVHSVYTRGAVNFLVEK 96
>gi|113411677 PREDICTED: hypothetical protein [Homo sapiens]
Length = 109
Score = 28.1 bits (61), Expect = 5.7
Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 34 GHRAELLRFPERSTEIGKLLSSYLQKKSDV--EDHSVHLLFSANRWEQVPLIKEK 86
G EL FPERSTE K+ +K++ ED++ HL+ S V + EK
Sbjct: 42 GFSEELQYFPERSTEKLKVFEWEEEKQTTATSEDNTKHLVHSVYTRGAVNFLVEK 96
>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
[Homo sapiens]
Length = 457
Score = 28.1 bits (61), Expect = 5.7
Identities = 10/26 (38%), Positives = 16/26 (61%)
Query: 100 FSGVAFTGAKENFSLDWCKQPDVGLP 125
F G+ TG + ++DW K+P G+P
Sbjct: 79 FYGINMTGKVDRNTIDWMKKPRCGVP 104
>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
[Homo sapiens]
Length = 607
Score = 28.1 bits (61), Expect = 5.7
Identities = 10/26 (38%), Positives = 16/26 (61%)
Query: 100 FSGVAFTGAKENFSLDWCKQPDVGLP 125
F G+ TG + ++DW K+P G+P
Sbjct: 79 FYGINMTGKVDRNTIDWMKKPRCGVP 104
>gi|154426306 kinesin family member 24 [Homo sapiens]
Length = 1368
Score = 28.1 bits (61), Expect = 5.7
Identities = 15/55 (27%), Positives = 27/55 (49%)
Query: 33 AGHRAELLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKL 87
A HRAE + +R T ++ ++ HL F +++Q PL+++KL
Sbjct: 727 AHHRAEYSQDSQRGTPARPASEAWTNIPPHQKEREEHLRFYHQQFQQPPLLQQKL 781
>gi|19923979 ADP-ribosylation factor-like 11 [Homo sapiens]
Length = 196
Score = 27.7 bits (60), Expect = 7.5
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 5/42 (11%)
Query: 7 ALIVLEGVDRAGKST-----QSRKLVEALCAAGHRAELLRFP 43
A +V+ G+D AGK+T + +LVE L G E L+ P
Sbjct: 13 AQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAP 54
>gi|207452735 epiplakin 1 [Homo sapiens]
Length = 5090
Score = 27.7 bits (60), Expect = 7.5
Identities = 45/174 (25%), Positives = 68/174 (39%), Gaps = 43/174 (24%)
Query: 16 RAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSAN 75
R+G++ R++V A+ A AE R P ++T G L+K+ D LF A
Sbjct: 1491 RSGRAAALRQVVSAVTALVEAAE--RQPLQATFRG------LRKQVSARD-----LFRAQ 1537
Query: 76 RWEQVPLIKEKLSQGVTLVVDRYAF-------------SGVAFTGAKENFSLDWCKQPDV 122
+ L ++LSQG T V + +GV G +E S+ + +
Sbjct: 1538 LISRKTL--DELSQGTTTVKEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHI 1595
Query: 123 GLPKPDLVLF---------------LQLQLADAAKRGAFGHERYENGAFQERAL 161
P LVL +L + +A K G FG E Y ERA+
Sbjct: 1596 LRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFKAGMFGKETYVKLLSAERAV 1649
>gi|45593142 kelch repeat and BTB (POZ) domain containing 5 [Homo
sapiens]
Length = 621
Score = 27.7 bits (60), Expect = 7.5
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 11/84 (13%)
Query: 11 LEGVDRAG-KSTQSRKLVEALCAAGHRAELLRFPERSTE----------IGKLLSSYLQK 59
L+ V RAG + +LV A C+ RA L PER+ E + ++L
Sbjct: 33 LDCVVRAGEREFPCHRLVLAACSPYFRARFLAEPERAGELHLEEVSPDVVAQVLHYLYTS 92
Query: 60 KSDVEDHSVHLLFSANRWEQVPLI 83
+ +++ SV LF+A Q+P I
Sbjct: 93 EIALDEASVQDLFAAAHRFQIPSI 116
>gi|68160947 secretogranin II precursor [Homo sapiens]
Length = 617
Score = 27.3 bits (59), Expect = 9.8
Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 15/98 (15%)
Query: 122 VGLPKPDLVLFLQLQLADAAKR---------GAFGHERYENGAFQERALRCFHQLMKDTT 172
+G+ + DL + QL+D + A G R +NG ERA R F + + D+
Sbjct: 288 LGIQEEDLRKESKDQLSDDVSKVIAYLKRLVNAAGSGRLQNGQNGERATRLFEKPL-DSQ 346
Query: 173 LNWKMVDASKSIEAVHEDIRVLSEDAIRTATEKPLGEL 210
+++++ S++++ ED+ + ++T EKP G +
Sbjct: 347 SIYQLIEISRNLQIPPEDL----IEMLKTG-EKPNGSV 379
>gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 1 [Homo sapiens]
Length = 953
Score = 27.3 bits (59), Expect = 9.8
Identities = 41/207 (19%), Positives = 80/207 (38%), Gaps = 40/207 (19%)
Query: 15 DRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKKSD--------VEDH 66
+R G+ T++ ++A+ LL ER E+ + L KK+ +E+
Sbjct: 100 ERVGQMTKTYNDIDAV------TRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQ 153
Query: 67 SVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKEN---------FSLDWC 117
H+ ++ +K++L Q T + V T K N F LD
Sbjct: 154 VEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSL 213
Query: 118 KQPDVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKM 177
++ L + ++VL R + E ++E+ + + +K+ +
Sbjct: 214 QKKLKDLEEENVVL-----------RSEASQLKTETITYEEKEQQLVNDCVKE------L 256
Query: 178 VDASKSIEAVHEDIRVLSEDAIRTATE 204
DA+ I ++ E++ +EDA R E
Sbjct: 257 RDANVQIASISEELAKKTEDAARQQEE 283
>gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 2 [Homo sapiens]
Length = 686
Score = 27.3 bits (59), Expect = 9.8
Identities = 41/207 (19%), Positives = 80/207 (38%), Gaps = 40/207 (19%)
Query: 15 DRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKKSD--------VEDH 66
+R G+ T++ ++A+ LL ER E+ + L KK+ +E+
Sbjct: 42 ERVGQMTKTYNDIDAV------TRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQ 95
Query: 67 SVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKEN---------FSLDWC 117
H+ ++ +K++L Q T + V T K N F LD
Sbjct: 96 VEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSL 155
Query: 118 KQPDVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKM 177
++ L + ++VL R + E ++E+ + + +K+ +
Sbjct: 156 QKKLKDLEEENVVL-----------RSEASQLKTETITYEEKEQQLVNDCVKE------L 198
Query: 178 VDASKSIEAVHEDIRVLSEDAIRTATE 204
DA+ I ++ E++ +EDA R E
Sbjct: 199 RDANVQIASISEELAKKTEDAARQQEE 225
>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
Length = 645
Score = 27.3 bits (59), Expect = 9.8
Identities = 9/26 (34%), Positives = 16/26 (61%)
Query: 100 FSGVAFTGAKENFSLDWCKQPDVGLP 125
F G+ TG + +++W K+P G+P
Sbjct: 117 FYGIPVTGVLDQTTIEWMKKPRCGVP 142
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 27.3 bits (59), Expect = 9.8
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 12/63 (19%)
Query: 11 LEGVDRAGKSTQSRKLVEALCAAGHR-----AELLRFPERSTEIGKLLS-------SYLQ 58
+ + R+ ++ L+E CAAG + E L PE TE + SYLQ
Sbjct: 426 VHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQ 485
Query: 59 KKS 61
+KS
Sbjct: 486 EKS 488
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 27.3 bits (59), Expect = 9.8
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 12/63 (19%)
Query: 11 LEGVDRAGKSTQSRKLVEALCAAGHR-----AELLRFPERSTEIGKLLS-------SYLQ 58
+ + R+ ++ L+E CAAG + E L PE TE + SYLQ
Sbjct: 426 VHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQ 485
Query: 59 KKS 61
+KS
Sbjct: 486 EKS 488
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,317,513
Number of Sequences: 37866
Number of extensions: 289912
Number of successful extensions: 737
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 728
Number of HSP's gapped (non-prelim): 26
length of query: 212
length of database: 18,247,518
effective HSP length: 98
effective length of query: 114
effective length of database: 14,536,650
effective search space: 1657178100
effective search space used: 1657178100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.