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Search of human proteins with 42476320
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42476320 sushi domain containing 1 [Homo sapiens]
(747 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42476320 sushi domain containing 1 [Homo sapiens] 1556 0.0
gi|56550049 uromodulin precursor [Homo sapiens] 102 1e-21
gi|59850812 uromodulin precursor [Homo sapiens] 102 1e-21
gi|24430141 fibrillin 1 precursor [Homo sapiens] 99 2e-20
gi|10190748 CEGP1 protein [Homo sapiens] 98 2e-20
gi|66346695 fibrillin 2 precursor [Homo sapiens] 96 9e-20
gi|40807489 egf-like module containing, mucin-like, hormone rece... 94 4e-19
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens] 94 5e-19
gi|23397691 egf-like module containing, mucin-like, hormone rece... 93 1e-18
gi|23397683 egf-like module containing, mucin-like, hormone rece... 93 1e-18
gi|46249414 latent transforming growth factor beta binding prote... 92 2e-18
gi|46249412 latent transforming growth factor beta binding prote... 92 2e-18
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] 92 2e-18
gi|148806925 EGF, latrophilin and seven transmembrane domain con... 91 3e-18
gi|23397681 egf-like module containing, mucin-like, hormone rece... 91 4e-18
gi|23397689 egf-like module containing, mucin-like, hormone rece... 91 4e-18
gi|4557733 latent transforming growth factor beta binding protei... 89 2e-17
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 87 4e-17
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 87 7e-17
gi|56237021 fibrillin 3 precursor [Homo sapiens] 86 1e-16
gi|110347437 latent transforming growth factor beta binding prot... 86 2e-16
gi|110347412 latent transforming growth factor beta binding prot... 86 2e-16
gi|110347431 latent transforming growth factor beta binding prot... 86 2e-16
gi|148886654 polydom [Homo sapiens] 86 2e-16
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 85 3e-16
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens] 83 1e-15
gi|194328809 latent transforming growth factor beta binding prot... 82 2e-15
gi|18497288 latent transforming growth factor beta binding prote... 82 2e-15
gi|23397693 egf-like module containing, mucin-like, hormone rece... 81 3e-15
gi|23397685 egf-like module containing, mucin-like, hormone rece... 81 3e-15
>gi|42476320 sushi domain containing 1 [Homo sapiens]
Length = 747
Score = 1556 bits (4029), Expect = 0.0
Identities = 747/747 (100%), Positives = 747/747 (100%)
Query: 1 MGRGPWDAGPSRRLLPLLLLLGLARGAAGAPGPDGLDVCATCHEHATCQQREGKKICICN 60
MGRGPWDAGPSRRLLPLLLLLGLARGAAGAPGPDGLDVCATCHEHATCQQREGKKICICN
Sbjct: 1 MGRGPWDAGPSRRLLPLLLLLGLARGAAGAPGPDGLDVCATCHEHATCQQREGKKICICN 60
Query: 61 YGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDG 120
YGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDG
Sbjct: 61 YGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDG 120
Query: 121 TFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCG 180
TFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCG
Sbjct: 121 TFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCG 180
Query: 181 TPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCG 240
TPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCG
Sbjct: 181 TPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCG 240
Query: 241 NPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTWRESTLTCTEILTK 300
NPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTWRESTLTCTEILTK
Sbjct: 241 NPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTWRESTLTCTEILTK 300
Query: 301 INDVSLFNDTCVRWQINSRRINPKISYVISIKGQRLDPMESVREETVNLTTDSRTPEVCL 360
INDVSLFNDTCVRWQINSRRINPKISYVISIKGQRLDPMESVREETVNLTTDSRTPEVCL
Sbjct: 301 INDVSLFNDTCVRWQINSRRINPKISYVISIKGQRLDPMESVREETVNLTTDSRTPEVCL 360
Query: 361 ALYPGTNYTVNISTAPPRRSMPAVIGFQTAEVDLLEDDGSFNISIFNETCLKLNRRSRKV 420
ALYPGTNYTVNISTAPPRRSMPAVIGFQTAEVDLLEDDGSFNISIFNETCLKLNRRSRKV
Sbjct: 361 ALYPGTNYTVNISTAPPRRSMPAVIGFQTAEVDLLEDDGSFNISIFNETCLKLNRRSRKV 420
Query: 421 GSEHMYQFTVLGQRWYLANFSHATSFNFTTREQVPVVCLDLYPTTDYTVNVTLLRSPKRH 480
GSEHMYQFTVLGQRWYLANFSHATSFNFTTREQVPVVCLDLYPTTDYTVNVTLLRSPKRH
Sbjct: 421 GSEHMYQFTVLGQRWYLANFSHATSFNFTTREQVPVVCLDLYPTTDYTVNVTLLRSPKRH 480
Query: 481 SVQITIATPPAVKQTISNISGFNETCLRWRSIKTADMEEMYLFHIWGQRWYQKEFAQEMT 540
SVQITIATPPAVKQTISNISGFNETCLRWRSIKTADMEEMYLFHIWGQRWYQKEFAQEMT
Sbjct: 481 SVQITIATPPAVKQTISNISGFNETCLRWRSIKTADMEEMYLFHIWGQRWYQKEFAQEMT 540
Query: 541 FNISSSSRDPEVCLDLRPGTNYNVSLRALSSELPVVISLTTQITEPPLPEVEFFTVHRGP 600
FNISSSSRDPEVCLDLRPGTNYNVSLRALSSELPVVISLTTQITEPPLPEVEFFTVHRGP
Sbjct: 541 FNISSSSRDPEVCLDLRPGTNYNVSLRALSSELPVVISLTTQITEPPLPEVEFFTVHRGP 600
Query: 601 LPRLRLRKAKEKNGPISSYQVLVLPLALQSTFSCDSEGASSFFSNASDADGYVAAELLAK 660
LPRLRLRKAKEKNGPISSYQVLVLPLALQSTFSCDSEGASSFFSNASDADGYVAAELLAK
Sbjct: 601 LPRLRLRKAKEKNGPISSYQVLVLPLALQSTFSCDSEGASSFFSNASDADGYVAAELLAK 660
Query: 661 DVPDDAMEIPIGDRLYYGEYYNAPLKRGSDYCIILRITSEWNKVRRHSCAVWAQVKDSSL 720
DVPDDAMEIPIGDRLYYGEYYNAPLKRGSDYCIILRITSEWNKVRRHSCAVWAQVKDSSL
Sbjct: 661 DVPDDAMEIPIGDRLYYGEYYNAPLKRGSDYCIILRITSEWNKVRRHSCAVWAQVKDSSL 720
Query: 721 MLLQMAGVGLGSLAVVIILTFLSFSAV 747
MLLQMAGVGLGSLAVVIILTFLSFSAV
Sbjct: 721 MLLQMAGVGLGSLAVVIILTFLSFSAV 747
>gi|56550049 uromodulin precursor [Homo sapiens]
Length = 640
Score = 102 bits (254), Expect = 1e-21
Identities = 51/120 (42%), Positives = 63/120 (52%), Gaps = 12/120 (10%)
Query: 39 CATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGF 98
C+ CH +ATC + E C C GF G+G T CVD +EC C ++SC NTPG F
Sbjct: 32 CSECHSNATCTEDEAVTTCTCQEGFTGDGLT-CVDLDECAIPGAHNCSANSSCVNTPGSF 90
Query: 99 YCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL--CRHGGRCVNTHGSFECYCMDGY 156
C+C EG+R + G CTD+DEC GL C CVN GS+ C C GY
Sbjct: 91 SCVCPEGFRL---------SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY 141
>gi|59850812 uromodulin precursor [Homo sapiens]
Length = 640
Score = 102 bits (254), Expect = 1e-21
Identities = 51/120 (42%), Positives = 63/120 (52%), Gaps = 12/120 (10%)
Query: 39 CATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGF 98
C+ CH +ATC + E C C GF G+G T CVD +EC C ++SC NTPG F
Sbjct: 32 CSECHSNATCTEDEAVTTCTCQEGFTGDGLT-CVDLDECAIPGAHNCSANSSCVNTPGSF 90
Query: 99 YCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL--CRHGGRCVNTHGSFECYCMDGY 156
C+C EG+R + G CTD+DEC GL C CVN GS+ C C GY
Sbjct: 91 SCVCPEGFRL---------SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY 141
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 98.6 bits (244), Expect = 2e-20
Identities = 72/238 (30%), Positives = 96/238 (40%), Gaps = 48/238 (20%)
Query: 47 TCQQREGKKICICNYGFVG-NGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEG 105
TC+ +G IC C+ G+ G G+T C D NEC+ GA CG H C NT G F C C G
Sbjct: 1295 TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAH-NCGKHAVCTNTAGSFKCSCSPG 1353
Query: 106 YRATNNNKTFIPNDGTFCTDIDEC-EVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEP 164
+ DG CTD+DEC + +C C NT GS+ C C +GY
Sbjct: 1354 W----------IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY-------- 1395
Query: 165 FHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGL 224
T D +CT++D E + + L + Y C VP +C +
Sbjct: 1396 ---TGDGFTCTDLD-----ECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDI 1447
Query: 225 GTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFE--SPGGKITSV 280
P + C C N P G+ R C+ G+E GG T V
Sbjct: 1448 DECSLPNI-CVFGTCHNLP----------------GLFRCECEIGYELDRSGGNCTDV 1488
Score = 96.7 bits (239), Expect = 7e-20
Identities = 68/224 (30%), Positives = 97/224 (43%), Gaps = 36/224 (16%)
Query: 26 GAAGAPGPDGLDVCA----TCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGA 81
G G G ++ C C +HA C G C C+ G++G+G +C D +EC G
Sbjct: 1313 GKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDG-IKCTDLDECSNG- 1370
Query: 82 TLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLCRHGGR 140
T +C H C NT G + C+C EGY DG CTD+DEC E LC + G+
Sbjct: 1371 THMCSQHADCKNTMGSYRCLCKEGYTG----------DGFTCTDLDECSENLNLCGN-GQ 1419
Query: 141 CVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLG 199
C+N G + C C G++ P+ D +C +ID C P + +L
Sbjct: 1420 CLNAPGGYRCECDMGFV---------PSADGKACEDIDECSLP-----NICVFGTCHNLP 1465
Query: 200 SQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPP 243
R C G+ + + +CT + P C NC N P
Sbjct: 1466 GLFRCECEIGY--ELDRSGGNCTDVNECLDPTT-CISGNCVNTP 1506
Score = 84.3 bits (207), Expect = 4e-16
Identities = 55/167 (32%), Positives = 75/167 (44%), Gaps = 25/167 (14%)
Query: 45 HATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLE 104
+ TC+ G C CN+GF+ + C+D +EC G +C N C NT G F C C E
Sbjct: 1902 NGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRN-GQCINTVGSFQCQCNE 1960
Query: 105 GYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEP 164
GY + DG C DI+EC + G C N GS+ C C GY +N
Sbjct: 1961 GYE--------VAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQN---- 2008
Query: 165 FHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQVRYACREGF 210
C +ID C PE+ +G +++ GS + C EGF
Sbjct: 2009 -------EKCEDIDECVEEPEI---CALGTCSNTEGS-FKCLCPEGF 2044
Score = 82.8 bits (203), Expect = 1e-15
Identities = 61/166 (36%), Positives = 77/166 (46%), Gaps = 26/166 (15%)
Query: 37 DVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPG 96
DVC +H C +G C C +G++ G +CVD +EC G CGN T C N G
Sbjct: 2135 DVC----KHGQCINTDGSYRCECPFGYILAGN-ECVDTDECSVGNP--CGNGT-CKNVIG 2186
Query: 97 GFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL-CRHGGRCVNTHGSFECYCMDG 155
GF C C EG+ P C DI+EC + L C RCVNT+GS+EC C G
Sbjct: 2187 GFECTCEEGFE---------PGPMMTCEDINECAQNPLLCAF--RCVNTYGSYECKCPVG 2235
Query: 156 YLPRNGPEPFHPTTDATSCTE--IDCGTPPEVPDGYIIGNYTSSLG 199
Y+ R E D C E DC T ++ +IG Y G
Sbjct: 2236 YVLR---EDRRMCKDEDECEEGKHDC-TEKQMECKNLIGTYMCICG 2277
Score = 82.8 bits (203), Expect = 1e-15
Identities = 47/124 (37%), Positives = 58/124 (46%), Gaps = 14/124 (11%)
Query: 36 LDVCATCHEHAT--CQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHN 93
LD CAT + C G C C GF + T C+D NEC L CG+ C N
Sbjct: 2486 LDECATKQHNCQFLCVNTIGGFTCKCPPGFTQH-HTSCIDNNECTSDINL-CGSKGICQN 2543
Query: 94 TPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCM 153
TPG F C C G+ + G+ C D+DECE + C+HG C N G + C C
Sbjct: 2544 TPGSFTCECQRGFS--------LDQTGSSCEDVDECEGNHRCQHG--CQNIIGGYRCSCP 2593
Query: 154 DGYL 157
GYL
Sbjct: 2594 QGYL 2597
Score = 80.1 bits (196), Expect = 7e-15
Identities = 58/199 (29%), Positives = 81/199 (40%), Gaps = 30/199 (15%)
Query: 44 EHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICL 103
++ C G C CN GF + R +C+D +EC+ C C N G + C C
Sbjct: 461 QNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNP---CAGG-ECINNQGSYTCQCR 516
Query: 104 EGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPE 163
GY++T T C DIDEC +G + GRC+NT GSF C C G
Sbjct: 517 AGYQSTLTR--------TECRDIDECLQNGRICNNGRCINTDGSFHCVCNAG-------- 560
Query: 164 PFHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCT 222
FH T D +C ++D C +G I + C+ GF + C
Sbjct: 561 -FHVTRDGKNCEDMDECSIRNMCLNGMCINE-----DGSFKCICKPGFQLASDGRY--CK 612
Query: 223 GLGTWESPKLHCQEINCGN 241
+ E+P + C C N
Sbjct: 613 DINECETPGI-CMNGRCVN 630
Score = 80.1 bits (196), Expect = 7e-15
Identities = 42/109 (38%), Positives = 55/109 (50%), Gaps = 13/109 (11%)
Query: 48 CQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C +G C+CN GF V C D +EC + G C N G F CIC G+
Sbjct: 546 CINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNG---MCINEDGSFKCICKPGF 602
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDG 155
+ + +DG +C DI+ECE G+C +G RCVNT GS+ C C G
Sbjct: 603 Q--------LASDGRYCKDINECETPGICMNG-RCVNTDGSYRCECFPG 642
Score = 80.1 bits (196), Expect = 7e-15
Identities = 66/225 (29%), Positives = 89/225 (39%), Gaps = 43/225 (19%)
Query: 48 CQQREGKKICICNYGFVGNGRTQ--CVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEG 105
C G C C+ G+ C+D +ECQ L G CHNT G + C C G
Sbjct: 1086 CVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGG--VCHNTEGSYRCECPPG 1143
Query: 106 YRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPF 165
++ + N C DI+ECE+S GRCVN G ++C C GY
Sbjct: 1144 HQLSPNISA--------CIDINECELSAHLCPNGRCVNLIGKYQCACNPGY--------- 1186
Query: 166 HPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLG 225
H T D C +ID + +G T+S GS +C+ GF +P+ SCT +
Sbjct: 1187 HSTPDRLFCVDID---ECSIMNGGCETFCTNSEGS-YECSCQPGFALMPDQ--RSCTDID 1240
Query: 226 TWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGF 270
E C C N P G R +C +GF
Sbjct: 1241 ECEDNPNICDGGQCTNIP----------------GEYRCLCYDGF 1269
Score = 77.8 bits (190), Expect = 3e-14
Identities = 50/160 (31%), Positives = 71/160 (44%), Gaps = 41/160 (25%)
Query: 34 DGLDVCAT---CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTS 90
+ +D C C +A C G C C G+ QC D+NECQ +C +H
Sbjct: 1807 EDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQ-EIPNIC-SHGQ 1864
Query: 91 CHNTPGGFYCICLEGYRATNNNKT--------------------------------FIPN 118
C +T G FYC+C G++ TN+++T FI +
Sbjct: 1865 CIDTVGSFYCLCHTGFK-TNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILS 1923
Query: 119 DGTFCTDIDECEV--SGLCRHGGRCVNTHGSFECYCMDGY 156
C D+DEC LCR+ G+C+NT GSF+C C +GY
Sbjct: 1924 HNNDCIDVDECASGNGNLCRN-GQCINTVGSFQCQCNEGY 1962
Score = 73.6 bits (179), Expect = 6e-13
Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 57/162 (35%)
Query: 36 LDVCAT----CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSC 91
LD C+ C +HA C+ G C+C G+ G+G T C D +EC L CGN C
Sbjct: 1364 LDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFT-CTDLDECSENLNL-CGNG-QC 1420
Query: 92 HNTPGGFYCICLEGYRATNNNKTFIPN-DGTFCTDIDECEVSGLCRHG------------ 138
N PGG+ C C G F+P+ DG C DIDEC + +C G
Sbjct: 1421 LNAPGGYRCECDMG---------FVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCE 1471
Query: 139 ----------------------------GRCVNTHGSFECYC 152
G CVNT GS+ C C
Sbjct: 1472 CEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDC 1513
Score = 72.8 bits (177), Expect = 1e-12
Identities = 67/266 (25%), Positives = 104/266 (39%), Gaps = 47/266 (17%)
Query: 48 CQQREGKKICICNYGFVGN-GRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C GK C CN G+ R CVD +EC + G T C N+ G + C C G+
Sbjct: 1171 CVNLIGKYQCACNPGYHSTPDRLFCVDIDECSI---MNGGCETFCTNSEGSYECSCQPGF 1227
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFH 166
+ ++ CTDIDECE + GG+C N G + C C DG++
Sbjct: 1228 ALMPDQRS--------CTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFM--------- 1270
Query: 167 PTTDATSCTEI-DCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLG 225
+ D +C ++ +C P + + G ++ GS + + C G+ T CT +
Sbjct: 1271 ASEDMKTCVDVNECDLNPNI---CLSGTCENTKGSFICH-CDMGYSGKKGKT--GCTDIN 1324
Query: 226 TWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKG 285
E NCG +HA+ + G + C G+ G K CT+
Sbjct: 1325 ECE-----IGAHNCG-----KHAV-----CTNTAGSFKCSCSPGWIGDGIK----CTDLD 1365
Query: 286 TWRESTLTCTEILTKINDVSLFNDTC 311
T C++ N + + C
Sbjct: 1366 ECSNGTHMCSQHADCKNTMGSYRCLC 1391
Score = 72.4 bits (176), Expect = 1e-12
Identities = 46/117 (39%), Positives = 57/117 (48%), Gaps = 17/117 (14%)
Query: 37 DVCATCHEHATCQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCHNTP 95
D+C + C+ G CICN G+ V + CVD NEC +L+C N C NTP
Sbjct: 732 DICP----NGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLN-SLLCDN-GQCRNTP 785
Query: 96 GGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYC 152
G F C C +G+ + KT C DIDECE S G C N+ GSF C C
Sbjct: 786 GSFVCTCPKGFIYKPDLKT--------CEDIDECESSPCI--NGVCKNSPGSFICEC 832
Score = 70.9 bits (172), Expect = 4e-12
Identities = 63/212 (29%), Positives = 84/212 (39%), Gaps = 32/212 (15%)
Query: 35 GLDVCATCHEHATCQQREGKKICICNYGF----VGNGRTQCVDKNECQFGATLVCGNHTS 90
G + C C T + E +C GF + NG+ D NEC+ +L H
Sbjct: 989 GTEECEECPMRNTPEYEE---LCPRGPGFATKEITNGKPFFKDINECKMIPSLC--THGK 1043
Query: 91 CHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFEC 150
C NT G F C C G+ + + CTDIDEC +S G+CVNT G FEC
Sbjct: 1044 CRNTIGSFKCRCDSGFALDSEERN--------CTDIDECRISPDLCGRGQCVNTPGDFEC 1095
Query: 151 YCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQVRYACREG 209
C +GY +G +C +ID C P + G + N S R C G
Sbjct: 1096 KCDEGY--ESG------FMMMKNCMDIDECQRDPLLCRGGVCHNTEGS----YRCECPPG 1143
Query: 210 FFSVPEDTVSSCTGLGTWESPKLHCQEINCGN 241
P +S+C + E C C N
Sbjct: 1144 HQLSP--NISACIDINECELSAHLCPNGRCVN 1173
Score = 69.7 bits (169), Expect = 9e-12
Identities = 39/111 (35%), Positives = 52/111 (46%), Gaps = 11/111 (9%)
Query: 48 CQQREGKKICICNYGFV-GNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C G C C G+V R C D++EC+ G C N G + CIC GY
Sbjct: 2221 CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGY 2280
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRCVNTHGSFECYCMDGY 156
+ DG C D +EC+ G+C +G RC+NT GS+ C C DG+
Sbjct: 2281 QRRP--------DGEGCVDENECQTKPGICENG-RCLNTRGSYTCECNDGF 2322
Score = 65.9 bits (159), Expect = 1e-10
Identities = 56/181 (30%), Positives = 79/181 (43%), Gaps = 40/181 (22%)
Query: 57 CICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI----CLEGYRATNN- 111
C C YGF G QC + + + G ++ C G C C RA +
Sbjct: 166 CACTYGFTG---PQC--ERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHP 220
Query: 112 -----------NKTFIPNDGT-FCTDIDECE-VSGLCRHGGRCVNTHGSFECYCMDGYLP 158
+ FIPN T C D+DEC+ + GLC+ GG C+NT GSFEC C G
Sbjct: 221 CEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQ-GGNCINTVGSFECKCPAG--- 276
Query: 159 RNGPEPFHPTTDAT-SCTEID-CGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPED 216
H + + C +ID C T P + +G G T+++ S C GF++ P+
Sbjct: 277 -------HKLNEVSQKCEDIDECSTIPGICEG---GECTNTVSSYF-CKCPPGFYTSPDG 325
Query: 217 T 217
T
Sbjct: 326 T 326
Score = 63.9 bits (154), Expect = 5e-10
Identities = 43/127 (33%), Positives = 61/127 (48%), Gaps = 18/127 (14%)
Query: 34 DGLDVCATCH--EHATCQQREGKKICICNYGFVGNGR-TQCVDKNECQFGATLVCGNHTS 90
+ +D C H +H CQ G C C G++ + + QCVD+NEC + +CG S
Sbjct: 2566 EDVDECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECL--SAHICGG-AS 2621
Query: 91 CHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLCRHGGRCVNTHGSFE 149
CHNT G + C+C G++ + C DI+EC C +G C NT G +
Sbjct: 2622 CHNTLGSYKCMCPAGFQYEQFSGG--------CQDINECGSAQAPCSYG--CSNTEGGYL 2671
Query: 150 CYCMDGY 156
C C GY
Sbjct: 2672 CGCPPGY 2678
Score = 63.2 bits (152), Expect = 9e-10
Identities = 61/214 (28%), Positives = 92/214 (42%), Gaps = 41/214 (19%)
Query: 44 EHATCQQREGKKICICNYGFVGN-GRTQCVDKNE-----------CQFGATL---VCGNH 88
E+ C G C CN GF + + +C+D E CQ G++ V +
Sbjct: 2303 ENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSE 2362
Query: 89 TSCHNTPG-GFYC-ICLEGYRATNNNKTFIPNDGTFCT---DIDECEV-SGLCRHGGRCV 142
C G G +C IC ++ T K P+ F T DIDEC+V +CR+G CV
Sbjct: 2363 CCCDGGRGWGPHCEIC--PFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNG-ECV 2419
Query: 143 NTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEI-DCGTPPEVPDGYIIGNYTSSLGSQ 201
N GS+ C C GY P TSC ++ +C P+ P +I N S
Sbjct: 2420 NDRGSYHCICKTGYT---------PDITGTSCVDLNECNQAPK-PCNFICKNTEGS---- 2465
Query: 202 VRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQ 235
+ +C +G+ + ++ SC L + + +CQ
Sbjct: 2466 YQCSCPKGY--ILQEDGRSCKDLDECATKQHNCQ 2497
Score = 59.7 bits (143), Expect = 1e-08
Identities = 40/111 (36%), Positives = 51/111 (45%), Gaps = 12/111 (10%)
Query: 52 EGKKICICNYGFVGNGRTQCV-DKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATN 110
E K +C GF N T + D +ECQ L G C NT G F C C GY
Sbjct: 1584 EYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGG--KCINTFGSFQCRCPTGY---- 1637
Query: 111 NNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNG 161
++ D C D++ECE G+C G C NT G++ C C Y+ NG
Sbjct: 1638 ----YLNEDTRVCDDVNECETPGICGPG-TCYNTVGNYTCICPPDYMQVNG 1683
Score = 59.3 bits (142), Expect = 1e-08
Identities = 41/133 (30%), Positives = 56/133 (42%), Gaps = 24/133 (18%)
Query: 52 EGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNN 111
E + +C G G D NEC +C N C N G + CIC GY +
Sbjct: 706 EYQALCSSGPGMTSAGS----DINECALDPD-ICPNGI-CENLRGTYKCICNSGYEVDST 759
Query: 112 NKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDA 171
K C DI+EC ++ L G+C NT GSF C C G++ + D
Sbjct: 760 GKN--------CVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYK---------PDL 802
Query: 172 TSCTEID-CGTPP 183
+C +ID C + P
Sbjct: 803 KTCEDIDECESSP 815
Score = 55.5 bits (132), Expect = 2e-07
Identities = 45/169 (26%), Positives = 64/169 (37%), Gaps = 62/169 (36%)
Query: 44 EHATCQQREGKKICICNYGFVGNGRTQ-CVDKNECQFGATLVCGNHTSCHNTPGGFYC-- 100
++ C+ G +C C GF+ + C D +EC+ + + C N+PG F C
Sbjct: 777 DNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCI----NGVCKNSPGSFICEC 832
Query: 101 -----------ICLEGYRAT------------NNNKTFIPND------------------ 119
IC+E + T N N + +
Sbjct: 833 SSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQV 892
Query: 120 ------------GTFCTDIDECEV-SGLCRHGGRCVNTHGSFECYCMDG 155
GT C DIDECEV G+C++ G CVNT GSF+C C G
Sbjct: 893 DPICGKGYSRIKGTQCEDIDECEVFPGVCKN-GLCVNTRGSFKCQCPSG 940
Score = 55.1 bits (131), Expect = 2e-07
Identities = 49/170 (28%), Positives = 68/170 (40%), Gaps = 32/170 (18%)
Query: 72 VDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEV 131
VD +EC+ VC N C N G F C C G+ N+K + C DIDEC+
Sbjct: 1765 VDIDECR-EIPGVCENGV-CINMVGSFRCECPVGF--FYNDKLLV------CEDIDECQN 1814
Query: 132 SGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYII 191
+C+ C+NT GS+ C C GY T C D E+P+
Sbjct: 1815 GPVCQRNAECINTAGSYRCDCKPGY----------RFTSTGQCN--DRNECQEIPNICSH 1862
Query: 192 GNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGN 241
G ++GS C GF + + T+ C + C+ CGN
Sbjct: 1863 GQCIDTVGS-FYCLCHTGFKTNDDQTM--CLDIN-------ECERDACGN 1902
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/87 (40%), Positives = 45/87 (51%), Gaps = 16/87 (18%)
Query: 115 FIPNDGT-FCTDIDEC-EVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDAT 172
F PN T DIDEC E+ GLC+ GG+C+NT GSF+C C GY + D
Sbjct: 1595 FRPNPITVILEDIDECQELPGLCQ-GGKCINTFGSFQCRCPTGY---------YLNEDTR 1644
Query: 173 SCTEI-DCGTPPEVPDG---YIIGNYT 195
C ++ +C TP G +GNYT
Sbjct: 1645 VCDDVNECETPGICGPGTCYNTVGNYT 1671
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/142 (26%), Positives = 56/142 (39%), Gaps = 26/142 (18%)
Query: 37 DVCATCHEHATCQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTS--CHN 93
++CA TC EG C+C GF + + +C D A G +S N
Sbjct: 2022 EICAL----GTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRN 2077
Query: 94 TPGGFYCICLEGYR--------ATNNNKTF----------IPNDGTFCTDIDECEVSGLC 135
C L+G T ++ F I D+DEC+ +C
Sbjct: 2078 HSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVC 2137
Query: 136 RHGGRCVNTHGSFECYCMDGYL 157
+H G+C+NT GS+ C C GY+
Sbjct: 2138 KH-GQCINTDGSYRCECPFGYI 2158
Score = 43.9 bits (102), Expect = 5e-04
Identities = 32/110 (29%), Positives = 47/110 (42%), Gaps = 16/110 (14%)
Query: 47 TCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
TCQ +G CIC G+ +C D +EC +C T C NT G F C+C EG+
Sbjct: 1988 TCQNLDGSYRCICPPGYSLQNE-KCEDIDEC-VEEPEICALGT-CSNTEGSFKCLCPEGF 2044
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVN----THGSFECYC 152
+++ + ++C E GG+C + H EC C
Sbjct: 2045 SLSSSGRRCQDLRMSYCYAKFE---------GGKCSSPKSRNHSKQECCC 2085
Score = 40.0 bits (92), Expect = 0.008
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 48 CQQREGKKICICNYGFVGNGRTQ-CVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C G C C G+ N T+ C D NEC+ +CG T C+NT G + CIC Y
Sbjct: 1622 CINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPG--ICGPGT-CYNTVGNYTCICPPDY 1678
Query: 107 RATNNNKTFIPNDGTFC 123
N + + C
Sbjct: 1679 MQVNGGNNCMDMRRSLC 1695
Score = 35.8 bits (81), Expect = 0.15
Identities = 65/261 (24%), Positives = 89/261 (34%), Gaps = 55/261 (21%)
Query: 58 ICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIP 117
IC G+ TQC D +EC+ VC N C NT G F C C G +
Sbjct: 895 ICGKGYSRIKGTQCEDIDECEVFPG-VCKNGL-CVNTRGSFKCQCPSGMT--------LD 944
Query: 118 NDGTFCTDI-----------DEC--EVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGP-- 162
G C DI +EC ++G R C + ++ + RN P
Sbjct: 945 ATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEY 1004
Query: 163 EPFHPTTDATSCTEIDCGTP--------PEVPDGYIIGNYTSSLGSQVRYACREGFFSVP 214
E P + EI G P +P G +++GS + C GF
Sbjct: 1005 EELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGS-FKCRCDSGFALDS 1063
Query: 215 EDTVSSCTGLGTWE-SPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESP 273
E+ +CT + SP L C C N P G C EG+ES
Sbjct: 1064 EE--RNCTDIDECRISPDL-CGRGQCVNTP----------------GDFECKCDEGYES- 1103
Query: 274 GGKITSVCTEKGTWRESTLTC 294
G + C + + L C
Sbjct: 1104 GFMMMKNCMDIDECQRDPLLC 1124
>gi|10190748 CEGP1 protein [Homo sapiens]
Length = 999
Score = 98.2 bits (243), Expect = 2e-20
Identities = 76/209 (36%), Positives = 92/209 (44%), Gaps = 38/209 (18%)
Query: 14 LLPLLLLLGLA---RGAAGAPGPDGLDVCAT----CHEHATCQQREGKKICICNYGFVGN 66
L PLLLL G RG A P D +D CA CH A CQ C C G+ G
Sbjct: 22 LPPLLLLAGAVPPGRGRAAGPQED-VDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGE 80
Query: 67 GRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDI 126
GR QC D +EC G L G C N PG + C C +G+ + +DG C D+
Sbjct: 81 GR-QCEDIDEC--GNELNGGCVHDCLNIPGNYRCTCFDGF--------MLAHDGHNCLDV 129
Query: 127 DEC-EVSGLCRHGGRCVNTHGSFECYCMDG-YLPRNGPEPFHPTTDATSCTEIDCGTP-- 182
DEC E +G C+H CVN GS+EC C +G +L N H + + SC D G
Sbjct: 130 DECLENNGGCQH--TCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHI 187
Query: 183 -PEVPDGYIIGNYTSSLGSQVRYACREGF 210
E P G V CR GF
Sbjct: 188 CKEAPRG------------SVACECRPGF 204
Score = 59.7 bits (143), Expect = 1e-08
Identities = 73/250 (29%), Positives = 93/250 (37%), Gaps = 43/250 (17%)
Query: 41 TCHEHATCQQREG------KKI-----CICNYGF-VGNGRTQCVDKNECQFGATLVCGNH 88
TC + CQ R G K I C C GF + C D +EC T C +
Sbjct: 320 TCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRT--CDH- 376
Query: 89 TSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRCVNTHGS 147
SC N PG F C C GY T C D +EC ++ G C+ CVNT GS
Sbjct: 377 -SCINHPGTFACACNRGYTLYGF---------THCGDTNECSINNGGCQQV--CVNTVGS 424
Query: 148 FECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACR 207
+EC C GY H + C E+ P V + S G C
Sbjct: 425 YECQCHPGY-------KLH--WNKKDCVEVKGLLPTSVSPRVSLHCGKSGGGDGCFLRCH 475
Query: 208 EGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVARYV-- 265
G + D + T + T++ + C N PE L HSS + RYV
Sbjct: 476 SG-IHLSSDVTTIRTSV-TFKLNEGKCSLKNAELFPEGLRPALPEKHSS-VKESFRYVNL 532
Query: 266 -CQEGFESPG 274
C G + PG
Sbjct: 533 TCSSGKQVPG 542
Score = 49.3 bits (116), Expect = 1e-05
Identities = 32/94 (34%), Positives = 42/94 (44%), Gaps = 20/94 (21%)
Query: 86 GNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEV-SGLCRHGGRCVNT 144
G +C +T G +C C G+ + DG C DIDEC+ +G C H C N
Sbjct: 292 GCDRTCKDTSTGVHCSCPVGFT--------LQLDGKTCKDIDECQTRNGGCDH--FCKNI 341
Query: 145 HGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID 178
GSF+C C G F TD SC ++D
Sbjct: 342 VGSFDCGCKKG---------FKLLTDEKSCQDVD 366
Score = 47.0 bits (110), Expect = 6e-05
Identities = 30/94 (31%), Positives = 38/94 (40%), Gaps = 8/94 (8%)
Query: 36 LDVCA---TCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCH 92
+D C+ TC +C G C CN G+ G T C D NEC G C
Sbjct: 365 VDECSLDRTCDH--SCINHPGTFACACNRGYTLYGFTHCGDTNECSINNG---GCQQVCV 419
Query: 93 NTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDI 126
NT G + C C GY+ N K + G T +
Sbjct: 420 NTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSV 453
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 96.3 bits (238), Expect = 9e-20
Identities = 86/288 (29%), Positives = 112/288 (38%), Gaps = 57/288 (19%)
Query: 21 LGLARGAAGAPGP--DGLDVCAT----CHEHAT------CQQREGKKICICNYGFVGNGR 68
+G A AG GP GL + C HA C C CN G+ +
Sbjct: 471 VGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDAN 530
Query: 69 TQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDE 128
C+D +EC C N C NTPG +YC C G++ T + C DIDE
Sbjct: 531 GDCIDVDECTSNP---CTNG-DCVNTPGSYYCKCHAGFQRTPTKQA--------CIDIDE 578
Query: 129 CEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPD 187
C +G+ GRCVNT GSF+C C G F TTD +C + D C T +
Sbjct: 579 CIQNGVLCKNGRCVNTDGSFQCICNAG---------FELTTDGKNCVDHDECTTTNMCLN 629
Query: 188 GYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKL----HC----QEINC 239
G I + C+ GF P CT + ++P + HC C
Sbjct: 630 GMCINE-----DGSFKCICKPGFVLAPNGRY--CTDVDECQTPGICMNGHCINSEGSFRC 682
Query: 240 GNPP----EMRHAILVGNH--SSRLGGVARYVCQEGFESPGGKITSVC 281
PP M + V H S+ GG+ + VC F PG S C
Sbjct: 683 DCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPF--PGAVTKSEC 728
Score = 95.5 bits (236), Expect = 2e-19
Identities = 67/222 (30%), Positives = 99/222 (44%), Gaps = 33/222 (14%)
Query: 25 RGAAGAPGPDGLDVCA-TCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATL 83
+G G D ++ A C HA+C G C C G++GNG +C+D +EC G T
Sbjct: 1360 KGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNG-IKCIDLDECSNG-TH 1417
Query: 84 VCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLCRHGGRCV 142
C + C NTPG + C C EG+ DG C+D+DEC E LC + G+C+
Sbjct: 1418 QCSINAQCVNTPGSYRCACSEGFTG----------DGFTCSDVDECAENINLCEN-GQCL 1466
Query: 143 NTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQ 201
N G++ C C G F P +D+ SC +ID C + ++L
Sbjct: 1467 NVPGAYRCECEMG---------FTPASDSRSCQDIDECSF-----QNICVFGTCNNLPGM 1512
Query: 202 VRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPP 243
C +G+ + T +CT + P ++C C N P
Sbjct: 1513 FHCICDDGY--ELDRTGGNCTDIDECADP-INCVNGLCVNTP 1551
Score = 85.1 bits (209), Expect = 2e-16
Identities = 66/211 (31%), Positives = 90/211 (42%), Gaps = 34/211 (16%)
Query: 36 LDVCATCHEHATCQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCHNT 94
L++ C H C +G CIC+ GF +T C+D +EC+ CGN T C NT
Sbjct: 1897 LEIPNVC-SHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHP---CGNGT-CKNT 1951
Query: 95 PGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECE--VSGLCRHGGRCVNTHGSFECYC 152
G + C+C G+ T+NN C DIDEC +CR+ GRC N GSF+C C
Sbjct: 1952 VGSYNCLCYPGFELTHNND---------CLDIDECSSFFGQVCRN-GRCFNEIGSFKCLC 2001
Query: 153 MDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFS 212
+GY T D +C ID +P G + GS R C G+
Sbjct: 2002 NEGY---------ELTPDGKNC--IDTNECVALPGSCSPGTCQNLEGS-FRCICPPGY-- 2047
Query: 213 VPEDTVSSCTGLGTWESPKLHCQEINCGNPP 243
E +C + + C +C N P
Sbjct: 2048 --EVKSENCIDINECDEDPNICLFGSCTNTP 2076
Score = 84.3 bits (207), Expect = 4e-16
Identities = 77/260 (29%), Positives = 103/260 (39%), Gaps = 65/260 (25%)
Query: 45 HATCQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICL 103
+ C+ G C CN GF + C D +EC+ L CG+ C NTPG F C C
Sbjct: 1086 YGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDL-CGSGI-CVNTPGSFECECF 1143
Query: 104 EGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGY------- 156
EGY + + N C DIDECE + L GG CVNT GSF+C C G+
Sbjct: 1144 EGYES---GFMMMKN----CMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSRE 1196
Query: 157 -------------LPRNGP-------------EPFHPTTDATSCTEIDCGTPPEVPDGYI 190
L RNG + T D CT+ID + +G
Sbjct: 1197 DCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDID---ECMIMNGGC 1253
Query: 191 IGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAIL 250
T+S GS +C EG+ +P+ SC + C N P+ I
Sbjct: 1254 DTQCTNSEGS-YECSCSEGYALMPDG--RSCADID------------ECENNPD----IC 1294
Query: 251 VGNHSSRLGGVARYVCQEGF 270
G + + G R +C +GF
Sbjct: 1295 DGGQCTNIPGEYRCLCYDGF 1314
Score = 76.6 bits (187), Expect = 8e-14
Identities = 62/209 (29%), Positives = 86/209 (41%), Gaps = 32/209 (15%)
Query: 36 LDVCATCHEHAT--CQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHN 93
LD C T + C G C C GF + T C+D NEC +L CG C N
Sbjct: 2533 LDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQH-HTACIDNNECGSQPSL-CGAKGICQN 2590
Query: 94 TPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCM 153
TPG F C C G+ + G C D+DEC+ + C+HG C N G + C C
Sbjct: 2591 TPGSFSCECQRGFS--------LDATGLNCEDVDECDGNHRCQHG--CQNILGGYRCGCP 2640
Query: 154 DGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFS 212
GY+ ++ D C+ + CG+ + ++LGS + AC GF
Sbjct: 2641 QGYIQH---YQWNQCVDENECSNPNACGS----------ASCYNTLGS-YKCACPSGFSF 2686
Query: 213 VPEDTVSSCTGLGTWESPKLHCQEINCGN 241
+ S+C + S K C C N
Sbjct: 2687 --DQFSSACHDVNECSSSKNPC-NYGCSN 2712
Score = 74.3 bits (181), Expect = 4e-13
Identities = 45/130 (34%), Positives = 60/130 (46%), Gaps = 22/130 (16%)
Query: 34 DGLDVCAT----CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHT 89
+ +D C+ C +A C G C C GF + CVD+NEC VC +H
Sbjct: 1849 EDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNEC-LEIPNVC-SHG 1906
Query: 90 SCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRH---GGRCVNTHG 146
C + G + CIC G++A+ D T C D+DECE RH G C NT G
Sbjct: 1907 LCVDLQGSYQCICHNGFKAS--------QDQTMCMDVDECE-----RHPCGNGTCKNTVG 1953
Query: 147 SFECYCMDGY 156
S+ C C G+
Sbjct: 1954 SYNCLCYPGF 1963
Score = 72.0 bits (175), Expect = 2e-12
Identities = 57/199 (28%), Positives = 86/199 (43%), Gaps = 29/199 (14%)
Query: 48 CQQREGKKICICNYGFVGN-GRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C G C CN G+ R C D +EC + G T C N+ G + C C EGY
Sbjct: 1216 CVNMIGTYQCSCNPGYQATPDRQGCTDIDECMI---MNGGCDTQCTNSEGSYECSCSEGY 1272
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFH 166
+ DG C DIDECE + GG+C N G + C C DG++
Sbjct: 1273 A--------LMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFM--------- 1315
Query: 167 PTTDATSCTEI-DCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLG 225
+ D +C ++ +C + + G ++ GS + + C+ G +SV + T + CT +
Sbjct: 1316 ASMDMKTCIDVNECDLNSNI---CMFGECENTKGSFICH-CQLG-YSVKKGT-TGCTDVD 1369
Query: 226 TWESPKLHC-QEINCGNPP 243
E +C +C N P
Sbjct: 1370 ECEIGAHNCDMHASCLNIP 1388
Score = 70.1 bits (170), Expect = 7e-12
Identities = 42/110 (38%), Positives = 52/110 (47%), Gaps = 13/110 (11%)
Query: 44 EHATCQQREGKKICICNYGFV-GNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCIC 102
E+ C G C C GF + C D +EC F V G +C+N PG F+CIC
Sbjct: 1461 ENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFG---TCNNLPGMFHCIC 1517
Query: 103 LEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYC 152
+GY + G CTDIDEC C +G CVNT G +EC C
Sbjct: 1518 DDGYE--------LDRTGGNCTDIDECADPINCVNG-LCVNTPGRYECNC 1558
Score = 66.6 bits (161), Expect = 8e-11
Identities = 46/140 (32%), Positives = 57/140 (40%), Gaps = 24/140 (17%)
Query: 31 PGPDGLDVCAT---------CHEHATCQQREGKKIC-----ICNYGFVGNGRTQCVDKNE 76
PG +D C C E +E + +C N G V GR D NE
Sbjct: 1017 PGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINE 1076
Query: 77 CQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCR 136
C+ + + C NT G F C C G+ + CTDIDEC +S
Sbjct: 1077 CKAFPGMC--TYGKCRNTIGSFKCRCNSGFALDMEERN--------CTDIDECRISPDLC 1126
Query: 137 HGGRCVNTHGSFECYCMDGY 156
G CVNT GSFEC C +GY
Sbjct: 1127 GSGICVNTPGSFECECFEGY 1146
Score = 65.9 bits (159), Expect = 1e-10
Identities = 50/162 (30%), Positives = 62/162 (38%), Gaps = 40/162 (24%)
Query: 42 CHEH----ATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGG 97
C H TC+ G C+C GF C+D +EC VC N C N G
Sbjct: 1938 CERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGR-CFNEIGS 1996
Query: 98 FYCICLEGYRATNNNKTFIPN------------------DGTF--------------CTD 125
F C+C EGY T + K I +G+F C D
Sbjct: 1997 FKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCID 2056
Query: 126 IDEC-EVSGLCRHGGRCVNTHGSFECYCMDGY-LPRNGPEPF 165
I+EC E +C G C NT G F+C C G+ L NG F
Sbjct: 2057 INECDEDPNICLFGS-CTNTPGGFQCLCPPGFVLSDNGRRCF 2097
Score = 64.3 bits (155), Expect = 4e-10
Identities = 46/133 (34%), Positives = 58/133 (43%), Gaps = 25/133 (18%)
Query: 48 CQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C +G C C G+ + +CVD +EC G CGN T C N G F C C EG+
Sbjct: 2187 CINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP--CGNGT-CTNVIGSFECNCNEGF 2243
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVSGL-CRHGGRCVNTHGSFECYCMDGYLPRNGPEPF 165
P C DI+EC + L C RC+NT GS+EC C GY R
Sbjct: 2244 E---------PGPMMNCEDINECAQNPLLCAF--RCMNTFGSYECTCPIGYALRE----- 2287
Query: 166 HPTTDATSCTEID 178
D C ++D
Sbjct: 2288 ----DQKMCKDLD 2296
Score = 63.9 bits (154), Expect = 5e-10
Identities = 61/214 (28%), Positives = 88/214 (41%), Gaps = 41/214 (19%)
Query: 44 EHATCQQREGKKICICNYGFVGNGR-TQCVDKNECQFGATL---VCGNHTSCHNTPGGFY 99
E+ C G C CN GF + T+C+D + A + +C +S N
Sbjct: 2350 ENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSE 2409
Query: 100 CICLEGYRATNNNKTFIPNDGT-----FCT----------DIDECEVSGLCRHGGRCVNT 144
C C +G R + P GT C DIDEC+V G+C+NT
Sbjct: 2410 CCC-DGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINT 2468
Query: 145 HGSFECYCMDGYLPRNGPEPFHPTTD--ATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQ 201
GSF C+C GY TTD TSC ++D C P+ P YI N S
Sbjct: 2469 MGSFRCFCKVGY-----------TTDISGTSCIDLDECSQSPK-PCNYICKNTEGS---- 2512
Query: 202 VRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQ 235
+ +C G+ V ++ +C L ++ + +CQ
Sbjct: 2513 YQCSCPRGY--VLQEDGKTCKDLDECQTKQHNCQ 2544
Score = 63.5 bits (153), Expect = 7e-10
Identities = 57/177 (32%), Positives = 68/177 (38%), Gaps = 29/177 (16%)
Query: 45 HATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLE 104
+ TC G C CN GF C D NEC L+C C NT G + C C
Sbjct: 2225 NGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQN-PLLCA--FRCMNTFGSYECTCPI 2281
Query: 105 GYRATNNNKTFIPNDGTFCTDIDECEVSGL--CR-HGGRCVNTHGSFECYCMDGYLPRNG 161
GY + K C D+DEC GL C G C N G+F C C G R
Sbjct: 2282 GYALREDQK--------MCKDLDEC-AEGLHDCESRGMMCKNLIGTFMCICPPGMARR-- 2330
Query: 162 PEPFHPTTDATSCT-EIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDT 217
D C E +C T P + + G + +GS R C EGF S T
Sbjct: 2331 -------PDGEGCVDENECRTKPGICEN---GRCVNIIGS-YRCECNEGFQSSSSGT 2376
Score = 62.4 bits (150), Expect = 1e-09
Identities = 41/120 (34%), Positives = 56/120 (46%), Gaps = 22/120 (18%)
Query: 59 CNYGFVGNGRT-QCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIP 117
C GF+ N RT C D +ECQ + G + C NT G F C C G++ + +
Sbjct: 261 CRRGFIPNIRTGACQDVDECQAIPGICQGGN--CINTVGSFECRCPAGHKQSETTQK--- 315
Query: 118 NDGTFCTDIDECE-VSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTE 176
C DIDEC + G+C G C NT GS+ C C GY+ +TD + C +
Sbjct: 316 -----CEDIDECSIIPGIC-ETGECSNTVGSYFCVCPRGYV---------TSTDGSRCID 360
Score = 61.6 bits (148), Expect = 3e-09
Identities = 74/277 (26%), Positives = 109/277 (39%), Gaps = 58/277 (20%)
Query: 56 ICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTF 115
+C G +GR D NEC +C N C N G + C C GY + +
Sbjct: 755 LCSSGVGITVDGR----DINECALDPD-ICANGI-CENLRGSYRCNCNSGYEPDASGRN- 807
Query: 116 IPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCT 175
C DIDEC V+ L G C NT GS+ C C GY+ R T+ +C
Sbjct: 808 -------CIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFR---------TETETCE 851
Query: 176 EI-DCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPK--- 231
+I +C + P + G ++LGS C G + S TGL +S K
Sbjct: 852 DINECESNP-----CVNGACRNNLGS-FNCECSPG-------SKLSSTGLICIDSLKGTC 898
Query: 232 -LHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTWRES 290
L+ Q+ C + A L + LG C+ ++ + C +G R
Sbjct: 899 WLNIQDSRC--EVNINGATLKSECCATLGAAWGSPCER------CELDTAC-PRGLARIK 949
Query: 291 TLTCTEILTKINDVSLFNDTCVRWQINSRRINPKISY 327
+TC + +N+ +F C N R +N K S+
Sbjct: 950 GVTCED----VNECEVFPGVCP----NGRCVNSKGSF 978
Score = 60.5 bits (145), Expect = 6e-09
Identities = 42/127 (33%), Positives = 59/127 (46%), Gaps = 18/127 (14%)
Query: 34 DGLDVCATCH--EHATCQQREGKKICICNYGFVGNGR-TQCVDKNECQFGATLVCGNHTS 90
+ +D C H +H CQ G C C G++ + + QCVD+NEC CG+ S
Sbjct: 2613 EDVDECDGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECS--NPNACGS-AS 2668
Query: 91 CHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRCVNTHGSFE 149
C+NT G + C C G+ + C D++EC S C +G C NT G +
Sbjct: 2669 CYNTLGSYKCACPSGFSFDQFSSA--------CHDVNECSSSKNPCNYG--CSNTEGGYL 2718
Query: 150 CYCMDGY 156
C C GY
Sbjct: 2719 CGCPPGY 2725
Score = 57.8 bits (138), Expect = 4e-08
Identities = 62/264 (23%), Positives = 84/264 (31%), Gaps = 100/264 (37%)
Query: 47 TCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
TCQ EG CIC G+ C+D NEC + SC NTPGGF C+C G+
Sbjct: 2031 TCQNLEGSFRCICPPGYEVKSEN-CIDINECDEDPNICLFG--SCTNTPGGFQCLCPPGF 2087
Query: 107 RATNNNK----------------------------------TFIPNDG-----TFCTDID 127
++N + + +P +G C D
Sbjct: 2088 VLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDD 2147
Query: 128 ECEVSGLCRHG--------------------------GRCVNTHGSFECYCMDGYLPRNG 161
E LC +G G+C+NT GSF C C GY
Sbjct: 2148 EVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGY----- 2202
Query: 162 PEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYT-SSLGSQVRYACREGFFSVPEDTVSS 220
T + C E G GN T +++ C EGF
Sbjct: 2203 ---------NLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGF---------- 2243
Query: 221 CTGLGTWESPKLHCQEIN-CGNPP 243
P ++C++IN C P
Sbjct: 2244 ------EPGPMMNCEDINECAQNP 2261
Score = 57.0 bits (136), Expect = 6e-08
Identities = 56/187 (29%), Positives = 77/187 (41%), Gaps = 43/187 (22%)
Query: 35 GLDVCAT-CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHN 93
G VC C C G C C YGF G QC + + + G N+ C
Sbjct: 176 GQPVCENGCQNGGRCI---GPNRCACVYGFTG---PQC--ERDYRTGPCFTQVNNQMCQG 227
Query: 94 TPGGFYCI----CLEGYRATNN------------NKTFIPNDGT-FCTDIDECE-VSGLC 135
G C C RA + + FIPN T C D+DEC+ + G+C
Sbjct: 228 QLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGIC 287
Query: 136 RHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDAT-SCTEID-CGTPPEVPDGYIIGN 193
+ GG C+NT GSFEC C G H ++ T C +ID C P + + G
Sbjct: 288 Q-GGNCINTVGSFECRCPAG----------HKQSETTQKCEDIDECSIIPGICE---TGE 333
Query: 194 YTSSLGS 200
++++GS
Sbjct: 334 CSNTVGS 340
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/125 (34%), Positives = 54/125 (43%), Gaps = 16/125 (12%)
Query: 39 CATCHEHATCQQREGKKICICNYGFVGNGRTQCV-DKNECQFGATLVCGNHTSCHNTPGG 97
C TC E +C GF N T + D +ECQ L G + C NT G
Sbjct: 1618 CETC---PPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGN--CINTFGS 1672
Query: 98 FYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRCVNTHGSFECYCMDGY 156
F C C +GY ++ D C DIDEC G+C G C NT G++ C C Y
Sbjct: 1673 FQCECPQGY--------YLSEDTRICEDIDECFAHPGVCGPG-TCYNTLGNYTCICPPEY 1723
Query: 157 LPRNG 161
+ NG
Sbjct: 1724 MQVNG 1728
Score = 53.9 bits (128), Expect = 5e-07
Identities = 50/157 (31%), Positives = 65/157 (41%), Gaps = 37/157 (23%)
Query: 57 CICNYGFVGNGRTQC-------VDKNECQFGATLVCGNHTSCHNTPG----GFYCICLEG 105
C +G G+G C V ++ C GN C P +Y +C G
Sbjct: 1579 CYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGN--PCETCPPVNSTEYYTLCPGG 1636
Query: 106 YRATNNNKTFIPNDGTFCT-DIDEC-EVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPE 163
+ F PN T DIDEC E+ GLC+ GG C+NT GSF+C C GY
Sbjct: 1637 -------EGFRPNPITIILEDIDECQELPGLCQ-GGNCINTFGSFQCECPQGY------- 1681
Query: 164 PFHPTTDATSCTEID-CGTPPEVPDG----YIIGNYT 195
+ + D C +ID C P V +GNYT
Sbjct: 1682 --YLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYT 1716
Score = 50.4 bits (119), Expect = 6e-06
Identities = 42/169 (24%), Positives = 63/169 (37%), Gaps = 62/169 (36%)
Query: 44 EHATCQQREGKKICICNYGFVGNGRTQ-CVDKNECQFGATLVCGNHTSCHNTPGGFYC-- 100
++ C+ G C C G+V T+ C D NEC+ + + +C N G F C
Sbjct: 822 DNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCV----NGACRNNLGSFNCEC 877
Query: 101 -----------ICLEGYRAT------------NNNKTFIPND------------------ 119
IC++ + T N N + ++
Sbjct: 878 SPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCEL 937
Query: 120 ------------GTFCTDIDECEV-SGLCRHGGRCVNTHGSFECYCMDG 155
G C D++ECEV G+C +G RCVN+ GSF C C +G
Sbjct: 938 DTACPRGLARIKGVTCEDVNECEVFPGVCPNG-RCVNSKGSFHCECPEG 985
Score = 38.9 bits (89), Expect = 0.018
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Query: 48 CQQREGKKICICNYGFVGNGRTQ-CVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C G C C G+ + T+ C D +EC F VCG T C+NT G + CIC Y
Sbjct: 1666 CINTFGSFQCECPQGYYLSEDTRICEDIDEC-FAHPGVCGPGT-CYNTLGNYTCICPPEY 1723
Query: 107 RATNNNKTFIPNDGTFC 123
N + +FC
Sbjct: 1724 MQVNGGHNCMDMRKSFC 1740
Score = 38.9 bits (89), Expect = 0.018
Identities = 43/142 (30%), Positives = 57/142 (40%), Gaps = 41/142 (28%)
Query: 47 TCQQREGKKICICNYGFVG-NGRTQCVD---------------KNECQFGAT--LVCGNH 88
TC G CIC ++ NG C+D +NE F T + C +
Sbjct: 1707 TCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTY 1766
Query: 89 T-------SCHN--TPG--GFYCIC--LEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGL 134
C TPG F IC + G+ TF + G DIDEC E+ G+
Sbjct: 1767 NVGKAWNKPCEPCPTPGTADFKTICGNIPGF-------TFDIHTGK-AVDIDECKEIPGI 1818
Query: 135 CRHGGRCVNTHGSFECYCMDGY 156
C +G C+N GSF C C G+
Sbjct: 1819 CANGV-CINQIGSFRCECPTGF 1839
Score = 38.5 bits (88), Expect = 0.023
Identities = 33/116 (28%), Positives = 45/116 (38%), Gaps = 22/116 (18%)
Query: 48 CQQREGKKICICNYGFVGNGRTQ-CVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C G C C G + TQ C D +EC +C C NT G ++C+C GY
Sbjct: 292 CINTVGSFECRCPAGHKQSETTQKCEDIDECSI-IPGICETG-ECSNTVGSYFCVCPRGY 349
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVSGLCRHG---GRCV----NTHGSFECYCMDG 155
+ DG+ C D + +G+C G GRC +C C G
Sbjct: 350 VTS--------TDGSRCID----QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
Score = 38.1 bits (87), Expect = 0.030
Identities = 58/252 (23%), Positives = 78/252 (30%), Gaps = 85/252 (33%)
Query: 59 CNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEG------------- 105
C G C D NEC+ VC N C N+ G F+C C EG
Sbjct: 941 CPRGLARIKGVTCEDVNECEVFPG-VCPNGR-CVNSKGSFHCECPEGLTLDGTGRVCLDI 998
Query: 106 -----YRATNNNKTFIPNDGTF----C---------TDIDEC------EVSGLCRHG--- 138
Y + ++ P G F C T+ +EC E LC G
Sbjct: 999 RMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGF 1058
Query: 139 ----------------------------GRCVNTHGSFECYCMDGYLPRNGPEPFHPTTD 170
G+C NT GSF+C C G F +
Sbjct: 1059 ANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSG---------FALDME 1109
Query: 171 ATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWES 229
+CT+ID C P++ I N S + GF + +C + E
Sbjct: 1110 ERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFM-----MMKNCMDIDECER 1164
Query: 230 PKLHCQEINCGN 241
L C+ C N
Sbjct: 1165 NPLLCRGGTCVN 1176
>gi|40807489 egf-like module containing, mucin-like, hormone
receptor-like sequence 1 [Homo sapiens]
Length = 886
Score = 94.4 bits (233), Expect = 4e-19
Identities = 73/290 (25%), Positives = 116/290 (40%), Gaps = 52/290 (17%)
Query: 42 CHEHATCQQREGKKICICNYGFVG-NGRT-------QCVDKNECQFGATLVCGNHTSCHN 93
C +ATC C C GF+ NG+ +C D +EC + CG ++SC N
Sbjct: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECS-QSPQPCGPNSSCKN 99
Query: 94 TPGGFYCICLEGYRATNNNKTFIPNDGTF-CTDIDECEVSGLCRHGGRCVNTHGSFECYC 152
G + C CL+G+ + N G F CTDI+EC S +C CVN+ GS+ C C
Sbjct: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSC 159
Query: 153 MDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPD----GYIIGNYTSSLGSQVRYACR 207
G++ RN ++C ++D C P P+ +GNY+ C
Sbjct: 160 QVGFISRN-----------STCEDVDECADPRACPEHATCNNTVGNYSC--------FCN 200
Query: 208 EGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQ 267
GF S +G +++ K C++I+ E + + + G C
Sbjct: 201 PGF--------ESSSGHLSFQGLKASCEDID-----ECTEMCPINSTCTNTPGSYFCTCH 247
Query: 268 EGFESPGGKITSV-----CTEKGTWRESTLTCTEILTKINDVSLFNDTCV 312
GF G++ C + R+ TC N + ++ C+
Sbjct: 248 PGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCI 297
Score = 92.0 bits (227), Expect = 2e-18
Identities = 60/196 (30%), Positives = 86/196 (43%), Gaps = 25/196 (12%)
Query: 40 ATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFY 99
+ C EH+ C G C C GF+ T C D +EC C H +C+NT G +
Sbjct: 140 SVCPEHSDCVNSMGSYSCSCQVGFISRNST-CEDVDEC--ADPRACPEHATCNNTVGNYS 196
Query: 100 CICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPR 159
C C G+ +++ + +F + C DIDEC + +C C NT GS+ C C G+ P
Sbjct: 197 CFCNPGFESSSGHLSFQGLKAS-CEDIDEC--TEMCPINSTCTNTPGSYFCTCHPGFAPS 253
Query: 160 NGPEPFHPTTDATSCTEID-CGTPPEV--PD------------GYIIGNYTSSLGSQV-- 202
NG F T C +ID C P P+ G I G + + GSQ
Sbjct: 254 NGQLNF--TDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDG 311
Query: 203 RYACREGFFSVPEDTV 218
++C+ F ED +
Sbjct: 312 NFSCQRVLFKCKEDVI 327
Score = 77.0 bits (188), Expect = 6e-14
Identities = 58/206 (28%), Positives = 89/206 (43%), Gaps = 29/206 (14%)
Query: 75 NECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL 134
N C+ + +C + +C NT +YC C +G+ ++N F + G C DIDEC S
Sbjct: 33 NNCR--DSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHF-KDPGVRCKDIDECSQSPQ 89
Query: 135 -CRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEI-DCGTPPEVPDGYIIG 192
C C N G ++C C+DG+ G + SCT+I +C T P+
Sbjct: 90 PCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEH---S 146
Query: 193 NYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVG 252
+ +S+GS +C+ GF S S+C + P+ + C N VG
Sbjct: 147 DCVNSMGS-YSCSCQVGFIS----RNSTCEDVDECADPRACPEHATCNN--------TVG 193
Query: 253 NHSSRLGGVARYVCQEGFESPGGKIT 278
N+S C GFES G ++
Sbjct: 194 NYSC--------FCNPGFESSSGHLS 211
>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
Length = 786
Score = 94.0 bits (232), Expect = 5e-19
Identities = 66/222 (29%), Positives = 95/222 (42%), Gaps = 23/222 (10%)
Query: 29 GAPGPDGLDVCATCHEHATCQQREGKKICICNYGF------VGNGRTQCVDKNECQFGAT 82
GA D C ++++C C CN GF + C D NEC +
Sbjct: 17 GAETQDSRGCARWCPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSK 73
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRC 141
+ CG + C NT G + C+C GY + KTF C D+DEC+ + LC+ G C
Sbjct: 74 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTC 133
Query: 142 VNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPD-GYIIGNYTSSLG 199
VNT GS+ C C+ G+ F P D CT++D C + D + N S
Sbjct: 134 VNTLGSYTCQCLPGF-------KFIP-EDPKVCTDVDECSSGQHQCDSSTVCFNTVGSYS 185
Query: 200 SQVR--YACREGFFSVPEDTVSSCTGLGTWESPK-LHCQEIN 238
+ R + R G + +DTV TW P +H Q ++
Sbjct: 186 CRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLS 227
>gi|23397691 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform f [Homo sapiens]
Length = 763
Score = 92.8 bits (229), Expect = 1e-18
Identities = 66/222 (29%), Positives = 95/222 (42%), Gaps = 23/222 (10%)
Query: 29 GAPGPDGLDVCATCHEHATCQQREGKKICICNYGF------VGNGRTQCVDKNECQFGAT 82
GA D C + ++C C CN GF + C D NEC +
Sbjct: 20 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 76
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRC 141
+ CG + C NT G + C+C GY + KTF C D+DEC+ + LC+ G C
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTC 136
Query: 142 VNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPD-GYIIGNYTSSLG 199
VNT GS+ C C+ G+ + PE D CT++D C + D + N S
Sbjct: 137 VNTLGSYTCQCLPGF--KLKPE------DPKLCTDVDECSSGQHQCDSSTVCFNTVGSYS 188
Query: 200 SQVR--YACREGFFSVPEDTVSSCTGLGTWESPK-LHCQEIN 238
+ R + R G + +DTV TW P +H Q ++
Sbjct: 189 CRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLS 230
>gi|23397683 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform b [Homo sapiens]
Length = 774
Score = 92.8 bits (229), Expect = 1e-18
Identities = 66/222 (29%), Positives = 95/222 (42%), Gaps = 23/222 (10%)
Query: 29 GAPGPDGLDVCATCHEHATCQQREGKKICICNYGF------VGNGRTQCVDKNECQFGAT 82
GA D C + ++C C CN GF + C D NEC +
Sbjct: 20 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 76
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRC 141
+ CG + C NT G + C+C GY + KTF C D+DEC+ + LC+ G C
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTC 136
Query: 142 VNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPD-GYIIGNYTSSLG 199
VNT GS+ C C+ G+ + PE D CT++D C + D + N S
Sbjct: 137 VNTLGSYTCQCLPGF--KLKPE------DPKLCTDVDECSSGQHQCDSSTVCFNTVGSYS 188
Query: 200 SQVR--YACREGFFSVPEDTVSSCTGLGTWESPK-LHCQEIN 238
+ R + R G + +DTV TW P +H Q ++
Sbjct: 189 CRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLS 230
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 92.0 bits (227), Expect = 2e-18
Identities = 66/211 (31%), Positives = 91/211 (43%), Gaps = 28/211 (13%)
Query: 34 DGLDVCATCH--EHATCQQREGKKICICNYGFVGNGR-TQCVDKNECQFGATLVCGNHTS 90
+ +D C H H C+ EG C+C+ G+ +G C D NEC + VC
Sbjct: 1120 EDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKS-VC-QRGD 1177
Query: 91 CHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFEC 150
C NT G + C C +G++ ++NKT C DI+ECE GLC G C+NT GSF C
Sbjct: 1178 CINTAGSYDCTCPDGFQL-DDNKT--------CQDINECEHPGLCGPQGECLNTEGSFHC 1228
Query: 151 YCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGF 210
C G F + D +C +ID V D + + + R C +G
Sbjct: 1229 VCQQG---------FSISADGRTCEDIDECVNNTVCDSH---GFCDNTAGSFRCLCYQG- 1275
Query: 211 FSVPEDTVSSCTGLGTWESPKLHCQEINCGN 241
F P+D C + E C E C N
Sbjct: 1276 FQAPQDG-QGCVDVNECELLSGVCGEAFCEN 1305
Score = 85.9 bits (211), Expect = 1e-16
Identities = 73/254 (28%), Positives = 102/254 (40%), Gaps = 50/254 (19%)
Query: 42 CHEHATCQQREGKKICICNYGFV--GNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFY 99
C C EG C+C GF +GRT C D +EC VC +H C NT G F
Sbjct: 1213 CGPQGECLNTEGSFHCVCQQGFSISADGRT-CEDIDECVNNT--VCDSHGFCDNTAGSFR 1269
Query: 100 CICLEGYRATNNNKTFIPNDGTFCTDIDECEV-SGLCRHGGRCVNTHGSFECYCMD---G 155
C+C +G++A P DG C D++ECE+ SG+C C N GSF C C D
Sbjct: 1270 CLCYQGFQA--------PQDGQGCVDVNECELLSGVCGEAF-CENVEGSFLCVCADENQE 1320
Query: 156 YLPRNGPEPFHPTTDATSCTEIDCGTPPE--------VPDGYIIGNYTSSLGSQVRYACR 207
Y P G +TD ++D P E + D + N + ++ C
Sbjct: 1321 YSPMTGQCRSRTSTD----LDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCT 1376
Query: 208 EGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGG------- 260
G + C LGT E ++ C P+ + + G SS GG
Sbjct: 1377 SGAGWGDNCEIFPCPVLGTAEFTEM-C--------PKGKGFVPAGESSSEAGGENYKDAD 1427
Query: 261 ----VARYVCQEGF 270
+ +C+ GF
Sbjct: 1428 ECLLFGQEICKNGF 1441
Score = 78.6 bits (192), Expect = 2e-14
Identities = 46/121 (38%), Positives = 58/121 (47%), Gaps = 17/121 (14%)
Query: 37 DVCATCHEHATCQQREGKKICICNYGFVGN-GRTQCVDKNECQFGATLVCGNHTSCHNTP 95
+VCA + C EG +C C+ G+ C D +ECQ G V G C NT
Sbjct: 1047 NVCA----NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQ---CKNTE 1099
Query: 96 GGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDG 155
G F C C +GY+ + C DIDEC+ LC H G+C NT GSF+C C G
Sbjct: 1100 GSFRCTCGQGYQLSAAKDQ--------CEDIDECQHRHLCAH-GQCRNTEGSFQCVCDQG 1150
Query: 156 Y 156
Y
Sbjct: 1151 Y 1151
Score = 72.8 bits (177), Expect = 1e-12
Identities = 49/128 (38%), Positives = 63/128 (49%), Gaps = 20/128 (15%)
Query: 34 DGLDVC---ATCHEHATCQQREGKKICI-CNYGFVG-NGRTQCVDKNECQFGATLVCGNH 88
+ +D C +TC + C G C+ C GF G NG QC+D +EC VC N
Sbjct: 998 EDIDECLNPSTCPDEQ-CVNSPGSYQCVPCTEGFRGWNG--QCLDVDECL--EPNVCANG 1052
Query: 89 TSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSF 148
C N G + C C +GY T ++K C DIDEC+ LC +G +C NT GSF
Sbjct: 1053 -DCSNLEGSYMCSCHKGYTRTPDHK--------HCRDIDECQQGNLCVNG-QCKNTEGSF 1102
Query: 149 ECYCMDGY 156
C C GY
Sbjct: 1103 RCTCGQGY 1110
Score = 71.2 bits (173), Expect = 3e-12
Identities = 63/233 (27%), Positives = 91/233 (39%), Gaps = 52/233 (22%)
Query: 48 CQQREGKKICICNYGFVGNGR-TQCVDKNECQFGATLVCGNHTSCHNTPGGFYC-ICLEG 105
C+ EG +CIC GF+ + T C+D +EC VCG C NT G F C C G
Sbjct: 932 CENTEGSFLCICPAGFMASEEGTNCIDVDECL--RPDVCG-EGHCVNTVGAFRCEYCDSG 988
Query: 106 YRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECY-CMDGYLPRNGPEP 164
YR T + C DIDEC C +CVN+ GS++C C +G+ NG
Sbjct: 989 YRMTQRGR---------CEDIDECLNPSTC-PDEQCVNSPGSYQCVPCTEGFRGWNG--- 1035
Query: 165 FHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGL 224
C ++D P V S+L +C +G+ P+
Sbjct: 1036 --------QCLDVDECLEPNV----CANGDCSNLEGSYMCSCHKGYTRTPDHK------- 1076
Query: 225 GTWESPKLHCQEIN-CGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGK 276
HC++I+ C + + V G R C +G++ K
Sbjct: 1077 --------HCRDIDEC-----QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAK 1116
Score = 68.9 bits (167), Expect = 2e-11
Identities = 59/217 (27%), Positives = 82/217 (37%), Gaps = 51/217 (23%)
Query: 69 TQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDE 128
TQ + NEC + H C N P + CIC EGYR + + C DIDE
Sbjct: 870 TQVTEINECTVNPDICGAGH--CINLPVRYTCICYEGYRFSEQQRK--------CVDIDE 919
Query: 129 C-EVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVP 186
C +V LC G RC NT GSF C C P F + + T+C ++D C P
Sbjct: 920 CTQVQHLCSQG-RCENTEGSFLCIC---------PAGFMASEEGTNCIDVDECLRPDVCG 969
Query: 187 DGYIIGNYTSSLGSQVRYACREGFFSVPE---DTVSSCTGLGTWESPKLHCQEINCGNPP 243
+G+ + +++G+ C G+ + + C T C + C N P
Sbjct: 970 EGHCV----NTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPST-------CPDEQCVNSP 1018
Query: 244 EMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSV 280
G C EGF G+ V
Sbjct: 1019 ---------------GSYQCVPCTEGFRGWNGQCLDV 1040
Score = 56.2 bits (134), Expect = 1e-07
Identities = 27/63 (42%), Positives = 37/63 (58%), Gaps = 14/63 (22%)
Query: 102 CLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNG 161
CL GY+ NN TFC DI+EC++ G+C + G C+NT GS+ C C G+ G
Sbjct: 612 CLPGYKRVNN---------TFCQDINECQLQGVCPN-GECLNTMGSYRCTCKIGF----G 657
Query: 162 PEP 164
P+P
Sbjct: 658 PDP 660
Score = 53.9 bits (128), Expect = 5e-07
Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 18/96 (18%)
Query: 85 CGNHTSCHN-----TPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEV----SGLC 135
CG C N G+ C C +GY T C D++EC+ LC
Sbjct: 1626 CGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMT--------CVDVNECDELNNRMSLC 1677
Query: 136 RHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDA 171
++ +C+NT GS++C C+ GY+P + P P A
Sbjct: 1678 KNA-KCINTDGSYKCLCLPGYVPSDKPNYCTPLNTA 1712
Score = 50.8 bits (120), Expect = 4e-06
Identities = 34/108 (31%), Positives = 47/108 (43%), Gaps = 17/108 (15%)
Query: 52 EGKKICICNYGFVGNGRTQCV-------DKNECQFGATLVCGNHTSCHNTPGGFYCICLE 104
E ++C GFV G + D +EC +C N C NT G+ C C +
Sbjct: 1397 EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGF-CLNTRPGYECYCKQ 1455
Query: 105 GYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYC 152
G T+ C D+DEC+ C G +CVNT GS+ C+C
Sbjct: 1456 G--------TYYDPVKLQCFDMDECQDPSSCIDG-QCVNTEGSYNCFC 1494
Score = 36.6 bits (83), Expect = 0.087
Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 5/95 (5%)
Query: 35 GLDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNT 94
G + C C + + C+ Y V N T C D NECQ VC N C NT
Sbjct: 590 GFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN--TFCQDINECQLQG--VCPNG-ECLNT 644
Query: 95 PGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDEC 129
G + C C G+ + +P+ + C
Sbjct: 645 MGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 679
Score = 35.8 bits (81), Expect = 0.15
Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 10/116 (8%)
Query: 49 QQREGKKICICNYG---FVGNGRTQCVDKNECQFGATLVCGNHTSCHNTP----GGFYCI 101
Q +E KK C N N V K EC + G++ P F +
Sbjct: 1342 QPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM 1401
Query: 102 CLEGYRATNNNKTFIPNDGTFCTDIDECEVSG--LCRHGGRCVNTHGSFECYCMDG 155
C +G ++ G D DEC + G +C++G C+NT +ECYC G
Sbjct: 1402 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGF-CLNTRPGYECYCKQG 1456
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 92.0 bits (227), Expect = 2e-18
Identities = 66/211 (31%), Positives = 91/211 (43%), Gaps = 28/211 (13%)
Query: 34 DGLDVCATCH--EHATCQQREGKKICICNYGFVGNGR-TQCVDKNECQFGATLVCGNHTS 90
+ +D C H H C+ EG C+C+ G+ +G C D NEC + VC
Sbjct: 794 EDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKS-VC-QRGD 851
Query: 91 CHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFEC 150
C NT G + C C +G++ ++NKT C DI+ECE GLC G C+NT GSF C
Sbjct: 852 CINTAGSYDCTCPDGFQL-DDNKT--------CQDINECEHPGLCGPQGECLNTEGSFHC 902
Query: 151 YCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGF 210
C G F + D +C +ID V D + + + R C +G
Sbjct: 903 VCQQG---------FSISADGRTCEDIDECVNNTVCDSH---GFCDNTAGSFRCLCYQG- 949
Query: 211 FSVPEDTVSSCTGLGTWESPKLHCQEINCGN 241
F P+D C + E C E C N
Sbjct: 950 FQAPQDG-QGCVDVNECELLSGVCGEAFCEN 979
Score = 85.9 bits (211), Expect = 1e-16
Identities = 73/254 (28%), Positives = 102/254 (40%), Gaps = 50/254 (19%)
Query: 42 CHEHATCQQREGKKICICNYGFV--GNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFY 99
C C EG C+C GF +GRT C D +EC VC +H C NT G F
Sbjct: 887 CGPQGECLNTEGSFHCVCQQGFSISADGRT-CEDIDECVNNT--VCDSHGFCDNTAGSFR 943
Query: 100 CICLEGYRATNNNKTFIPNDGTFCTDIDECEV-SGLCRHGGRCVNTHGSFECYCMD---G 155
C+C +G++A P DG C D++ECE+ SG+C C N GSF C C D
Sbjct: 944 CLCYQGFQA--------PQDGQGCVDVNECELLSGVCGEAF-CENVEGSFLCVCADENQE 994
Query: 156 YLPRNGPEPFHPTTDATSCTEIDCGTPPE--------VPDGYIIGNYTSSLGSQVRYACR 207
Y P G +TD ++D P E + D + N + ++ C
Sbjct: 995 YSPMTGQCRSRTSTD----LDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCT 1050
Query: 208 EGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGG------- 260
G + C LGT E ++ C P+ + + G SS GG
Sbjct: 1051 SGAGWGDNCEIFPCPVLGTAEFTEM-C--------PKGKGFVPAGESSSEAGGENYKDAD 1101
Query: 261 ----VARYVCQEGF 270
+ +C+ GF
Sbjct: 1102 ECLLFGQEICKNGF 1115
Score = 78.6 bits (192), Expect = 2e-14
Identities = 46/121 (38%), Positives = 58/121 (47%), Gaps = 17/121 (14%)
Query: 37 DVCATCHEHATCQQREGKKICICNYGFVGN-GRTQCVDKNECQFGATLVCGNHTSCHNTP 95
+VCA + C EG +C C+ G+ C D +ECQ G V G C NT
Sbjct: 721 NVCA----NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQ---CKNTE 773
Query: 96 GGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDG 155
G F C C +GY+ + C DIDEC+ LC H G+C NT GSF+C C G
Sbjct: 774 GSFRCTCGQGYQLSAAKDQ--------CEDIDECQHRHLCAH-GQCRNTEGSFQCVCDQG 824
Query: 156 Y 156
Y
Sbjct: 825 Y 825
Score = 72.8 bits (177), Expect = 1e-12
Identities = 49/128 (38%), Positives = 63/128 (49%), Gaps = 20/128 (15%)
Query: 34 DGLDVC---ATCHEHATCQQREGKKICI-CNYGFVG-NGRTQCVDKNECQFGATLVCGNH 88
+ +D C +TC + C G C+ C GF G NG QC+D +EC VC N
Sbjct: 672 EDIDECLNPSTCPDEQ-CVNSPGSYQCVPCTEGFRGWNG--QCLDVDECL--EPNVCANG 726
Query: 89 TSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSF 148
C N G + C C +GY T ++K C DIDEC+ LC +G +C NT GSF
Sbjct: 727 -DCSNLEGSYMCSCHKGYTRTPDHK--------HCRDIDECQQGNLCVNG-QCKNTEGSF 776
Query: 149 ECYCMDGY 156
C C GY
Sbjct: 777 RCTCGQGY 784
Score = 71.2 bits (173), Expect = 3e-12
Identities = 63/233 (27%), Positives = 91/233 (39%), Gaps = 52/233 (22%)
Query: 48 CQQREGKKICICNYGFVGNGR-TQCVDKNECQFGATLVCGNHTSCHNTPGGFYC-ICLEG 105
C+ EG +CIC GF+ + T C+D +EC VCG C NT G F C C G
Sbjct: 606 CENTEGSFLCICPAGFMASEEGTNCIDVDECL--RPDVCG-EGHCVNTVGAFRCEYCDSG 662
Query: 106 YRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECY-CMDGYLPRNGPEP 164
YR T + C DIDEC C +CVN+ GS++C C +G+ NG
Sbjct: 663 YRMTQRGR---------CEDIDECLNPSTC-PDEQCVNSPGSYQCVPCTEGFRGWNG--- 709
Query: 165 FHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGL 224
C ++D P V S+L +C +G+ P+
Sbjct: 710 --------QCLDVDECLEPNV----CANGDCSNLEGSYMCSCHKGYTRTPDHK------- 750
Query: 225 GTWESPKLHCQEIN-CGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGK 276
HC++I+ C + + V G R C +G++ K
Sbjct: 751 --------HCRDIDEC-----QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAK 790
Score = 68.9 bits (167), Expect = 2e-11
Identities = 59/217 (27%), Positives = 82/217 (37%), Gaps = 51/217 (23%)
Query: 69 TQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDE 128
TQ + NEC + H C N P + CIC EGYR + + C DIDE
Sbjct: 544 TQVTEINECTVNPDICGAGH--CINLPVRYTCICYEGYRFSEQQRK--------CVDIDE 593
Query: 129 C-EVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVP 186
C +V LC G RC NT GSF C C P F + + T+C ++D C P
Sbjct: 594 CTQVQHLCSQG-RCENTEGSFLCIC---------PAGFMASEEGTNCIDVDECLRPDVCG 643
Query: 187 DGYIIGNYTSSLGSQVRYACREGFFSVPE---DTVSSCTGLGTWESPKLHCQEINCGNPP 243
+G+ + +++G+ C G+ + + C T C + C N P
Sbjct: 644 EGHCV----NTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPST-------CPDEQCVNSP 692
Query: 244 EMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSV 280
G C EGF G+ V
Sbjct: 693 ---------------GSYQCVPCTEGFRGWNGQCLDV 714
Score = 56.2 bits (134), Expect = 1e-07
Identities = 27/63 (42%), Positives = 37/63 (58%), Gaps = 14/63 (22%)
Query: 102 CLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNG 161
CL GY+ NN TFC DI+EC++ G+C + G C+NT GS+ C C G+ G
Sbjct: 286 CLPGYKRVNN---------TFCQDINECQLQGVCPN-GECLNTMGSYRCTCKIGF----G 331
Query: 162 PEP 164
P+P
Sbjct: 332 PDP 334
Score = 53.9 bits (128), Expect = 5e-07
Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 18/96 (18%)
Query: 85 CGNHTSCHN-----TPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEV----SGLC 135
CG C N G+ C C +GY T C D++EC+ LC
Sbjct: 1300 CGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMT--------CVDVNECDELNNRMSLC 1351
Query: 136 RHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDA 171
++ +C+NT GS++C C+ GY+P + P P A
Sbjct: 1352 KNA-KCINTDGSYKCLCLPGYVPSDKPNYCTPLNTA 1386
Score = 50.8 bits (120), Expect = 4e-06
Identities = 34/108 (31%), Positives = 47/108 (43%), Gaps = 17/108 (15%)
Query: 52 EGKKICICNYGFVGNGRTQCV-------DKNECQFGATLVCGNHTSCHNTPGGFYCICLE 104
E ++C GFV G + D +EC +C N C NT G+ C C +
Sbjct: 1071 EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGF-CLNTRPGYECYCKQ 1129
Query: 105 GYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYC 152
G T+ C D+DEC+ C G +CVNT GS+ C+C
Sbjct: 1130 G--------TYYDPVKLQCFDMDECQDPSSCIDG-QCVNTEGSYNCFC 1168
Score = 36.6 bits (83), Expect = 0.087
Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 5/95 (5%)
Query: 35 GLDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNT 94
G + C C + + C+ Y V N T C D NECQ VC N C NT
Sbjct: 264 GFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN--TFCQDINECQLQG--VCPNG-ECLNT 318
Query: 95 PGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDEC 129
G + C C G+ + +P+ + C
Sbjct: 319 MGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 353
Score = 35.8 bits (81), Expect = 0.15
Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 10/116 (8%)
Query: 49 QQREGKKICICNYG---FVGNGRTQCVDKNECQFGATLVCGNHTSCHNTP----GGFYCI 101
Q +E KK C N N V K EC + G++ P F +
Sbjct: 1016 QPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM 1075
Query: 102 CLEGYRATNNNKTFIPNDGTFCTDIDECEVSG--LCRHGGRCVNTHGSFECYCMDG 155
C +G ++ G D DEC + G +C++G C+NT +ECYC G
Sbjct: 1076 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGF-CLNTRPGYECYCKQG 1130
>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
Length = 835
Score = 92.0 bits (227), Expect = 2e-18
Identities = 59/193 (30%), Positives = 83/193 (43%), Gaps = 20/193 (10%)
Query: 29 GAPGPDGLDVCATCHEHATCQQREGKKICICNYGF------VGNGRTQCVDKNECQFGAT 82
GA D C ++++C C CN GF + C D NEC +
Sbjct: 17 GAETQDSRGCARWCPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSK 73
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRC 141
+ CG + C NT G + C+C GY + KTF C D+DEC+ + LC+ G C
Sbjct: 74 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTC 133
Query: 142 VNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQ 201
VNT GS+ C C+ G+ + PE TD CT G P + + N S
Sbjct: 134 VNTLGSYTCQCLPGF--KFIPEDPKVCTDVNECTS---GQNPCHSSTHCLNNVGS----- 183
Query: 202 VRYACREGFFSVP 214
+ CR G+ +P
Sbjct: 184 YQCRCRPGWQPIP 196
Score = 70.9 bits (172), Expect = 4e-12
Identities = 43/124 (34%), Positives = 56/124 (45%), Gaps = 8/124 (6%)
Query: 42 CHEHATCQQREGKKICIC--NYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFY 99
C + TC G C C + F+ C D NEC G C + T C N G +
Sbjct: 127 CKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQN-PCHSSTHCLNNVGSYQ 185
Query: 100 CICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL--CRHGGRCVNTHGSFECYCMDGYL 157
C C G++ + PN+ T C D+DEC SG C C NT GS+ C C G+
Sbjct: 186 CRCRPGWQPIPGSPNG-PNN-TVCEDVDECS-SGQHQCDSSTVCFNTVGSYSCRCRPGWK 242
Query: 158 PRNG 161
PR+G
Sbjct: 243 PRHG 246
>gi|148806925 EGF, latrophilin and seven transmembrane domain
containing 1 [Homo sapiens]
Length = 690
Score = 91.3 bits (225), Expect = 3e-18
Identities = 41/96 (42%), Positives = 56/96 (58%), Gaps = 3/96 (3%)
Query: 42 CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI 101
C +A C+ R G + C CN GF GNG T C D NEC T CG + +C NT G +YC+
Sbjct: 27 CLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECG-NLTQSCGENANCTNTEGSYYCM 85
Query: 102 CLEGYRATNNNKTFIPNDGTFCTD--IDECEVSGLC 135
C+ G+R+++N FI NDGT C + C + +C
Sbjct: 86 CVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNVC 121
Score = 50.4 bits (119), Expect = 6e-06
Identities = 32/101 (31%), Positives = 41/101 (40%), Gaps = 4/101 (3%)
Query: 79 FGATLVCGNHTSCHNTP--GGFYCICLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLC 135
F L C +C TP C G A N F N T C D +EC ++ C
Sbjct: 10 FSTLLNCSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECGNLTQSC 69
Query: 136 RHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTE 176
C NT GS+ C C+ G+ + + F T D T C E
Sbjct: 70 GENANCTNTEGSYYCMCVPGFRSSSNQDRF-ITNDGTVCIE 109
>gi|23397681 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform a [Homo sapiens]
Length = 823
Score = 90.9 bits (224), Expect = 4e-18
Identities = 59/193 (30%), Positives = 82/193 (42%), Gaps = 20/193 (10%)
Query: 29 GAPGPDGLDVCATCHEHATCQQREGKKICICNYGF------VGNGRTQCVDKNECQFGAT 82
GA D C + ++C C CN GF + C D NEC +
Sbjct: 20 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 76
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRC 141
+ CG + C NT G + C+C GY + KTF C D+DEC+ + LC+ G C
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTC 136
Query: 142 VNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQ 201
VNT GS+ C C+ G+ + PE TD CT G P + + N S
Sbjct: 137 VNTLGSYTCQCLPGF--KLKPEDPKLCTDVNECTS---GQNPCHSSTHCLNNVGS----- 186
Query: 202 VRYACREGFFSVP 214
+ CR G+ +P
Sbjct: 187 YQCRCRPGWQPIP 199
Score = 68.6 bits (166), Expect = 2e-11
Identities = 44/124 (35%), Positives = 55/124 (44%), Gaps = 8/124 (6%)
Query: 42 CHEHATCQQREGKKICICNYGFVGNGRTQ--CVDKNECQFGATLVCGNHTSCHNTPGGFY 99
C + TC G C C GF C D NEC G C + T C N G +
Sbjct: 130 CKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQN-PCHSSTHCLNNVGSYQ 188
Query: 100 CICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL--CRHGGRCVNTHGSFECYCMDGYL 157
C C G++ + PN+ T C D+DEC SG C C NT GS+ C C G+
Sbjct: 189 CRCRPGWQPIPGSPNG-PNN-TVCEDVDECS-SGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Query: 158 PRNG 161
PR+G
Sbjct: 246 PRHG 249
>gi|23397689 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform e [Homo sapiens]
Length = 812
Score = 90.9 bits (224), Expect = 4e-18
Identities = 59/193 (30%), Positives = 82/193 (42%), Gaps = 20/193 (10%)
Query: 29 GAPGPDGLDVCATCHEHATCQQREGKKICICNYGF------VGNGRTQCVDKNECQFGAT 82
GA D C + ++C C CN GF + C D NEC +
Sbjct: 20 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 76
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRC 141
+ CG + C NT G + C+C GY + KTF C D+DEC+ + LC+ G C
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTC 136
Query: 142 VNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQ 201
VNT GS+ C C+ G+ + PE TD CT G P + + N S
Sbjct: 137 VNTLGSYTCQCLPGF--KLKPEDPKLCTDVNECTS---GQNPCHSSTHCLNNVGS----- 186
Query: 202 VRYACREGFFSVP 214
+ CR G+ +P
Sbjct: 187 YQCRCRPGWQPIP 199
Score = 68.6 bits (166), Expect = 2e-11
Identities = 44/124 (35%), Positives = 55/124 (44%), Gaps = 8/124 (6%)
Query: 42 CHEHATCQQREGKKICICNYGFVGNGRTQ--CVDKNECQFGATLVCGNHTSCHNTPGGFY 99
C + TC G C C GF C D NEC G C + T C N G +
Sbjct: 130 CKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQN-PCHSSTHCLNNVGSYQ 188
Query: 100 CICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL--CRHGGRCVNTHGSFECYCMDGYL 157
C C G++ + PN+ T C D+DEC SG C C NT GS+ C C G+
Sbjct: 189 CRCRPGWQPIPGSPNG-PNN-TVCEDVDECS-SGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Query: 158 PRNG 161
PR+G
Sbjct: 246 PRHG 249
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 88.6 bits (218), Expect = 2e-17
Identities = 66/256 (25%), Positives = 104/256 (40%), Gaps = 53/256 (20%)
Query: 48 CQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI-CLEGY 106
C EG C C+ G++ + C D NEC+ T G C N+PG + C+ C EGY
Sbjct: 945 CTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGR---CVNSPGSYTCLACEEGY 1001
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFH 166
R + + C D++EC G+C H G+C N GSF C C GY
Sbjct: 1002 RGQSGS----------CVDVNECLTPGVCAH-GKCTNLEGSFRCSCEQGY---------E 1041
Query: 167 PTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDT----VSSC 221
T+D C ++D C + P G + ++ GS AC G++ + T + C
Sbjct: 1042 VTSDEKGCQDVDECASRASCPTGLCL----NTEGSFACSACENGYWVNEDGTACEDLDEC 1097
Query: 222 -------TGLGTWESPKLHCQEINCGNPP-------------EMRHAILVGNHSSRLGGV 261
+G+ T + C++ + G P E + +G G
Sbjct: 1098 AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGS 1157
Query: 262 ARYVCQEGFESPGGKI 277
+ +C +GF+ G +
Sbjct: 1158 YQCLCPQGFQLANGTV 1173
Score = 80.1 bits (196), Expect = 7e-15
Identities = 66/233 (28%), Positives = 93/233 (39%), Gaps = 53/233 (22%)
Query: 71 CVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECE 130
C D +EC+ + G C NT G + C+C +G++ N GT C D++EC
Sbjct: 1133 CEDVDECEDPQSSCLGGE--CKNTVGSYQCLCPQGFQLAN---------GTVCEDVNECM 1181
Query: 131 VSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPDGY 189
C G C+N+HGSF C C G++ G TSC ++D C T G+
Sbjct: 1182 GEEHCAPHGECLNSHGSFFCLCAPGFVSAEG---------GTSCQDVDECATTDPCVGGH 1232
Query: 190 IIGNYTSSLGSQVRYACREGFFSVPED----TVSSCTG-----LGTWE---SP-----KL 232
+ S C GF PE + C GTW+ SP L
Sbjct: 1233 CVNTEGS-----FNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVL 1287
Query: 233 HCQ-------EINCGNPPEMRHAILVGNHS--SRLGGVARYVCQEGFE-SPGG 275
CQ +C + E + + G+H G R +C +GFE SP G
Sbjct: 1288 GCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSG 1340
Score = 75.5 bits (184), Expect = 2e-13
Identities = 46/135 (34%), Positives = 59/135 (43%), Gaps = 15/135 (11%)
Query: 27 AAGAPGPDGLDVCATCHE--HATCQQREGKKICICNYGFVGNGRT-QCVDKNECQFGATL 83
A G +D CAT C EG C+C GF + + +CVD +EC+
Sbjct: 1210 AEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDP 1269
Query: 84 VCGNHTSCHNTPGGFYCI--CLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRC 141
VCG C N+PG + C+ C G+ N C DIDEC +C G C
Sbjct: 1270 VCGT-WKCENSPGSYRCVLGCQPGFHMAPNGD---------CIDIDECANDTMCGSHGFC 1319
Query: 142 VNTHGSFECYCMDGY 156
NT GSF C C G+
Sbjct: 1320 DNTDGSFRCLCDQGF 1334
Score = 74.3 bits (181), Expect = 4e-13
Identities = 62/208 (29%), Positives = 86/208 (41%), Gaps = 44/208 (21%)
Query: 75 NECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL 134
+ C GAT VCG T C N P G+ C+C GY+ + +CTD +EC +
Sbjct: 846 DRCAAGATNVCGPGT-CVNLPDGYRCVCSPGYQLHPSQ--------AYCTDDNEC-LRDP 895
Query: 135 CRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDAT-SCTEIDCGTPPEVPDGYIIGN 193
C+ GRC+N GS+ C+C GY T+ AT C +I+ P V G G
Sbjct: 896 CKGKGRCINRVGSYSCFCYPGYT--------LATSGATQECQDINECEQPGVCSG---GQ 944
Query: 194 YTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEIN-CGNPPEMRHAILVG 252
T++ GS C +G+ V K HCQ+IN C +P V
Sbjct: 945 CTNTEGS-YHCECDQGYIMV----------------RKGHCQDINECRHPGTCPDGRCVN 987
Query: 253 NHSSRLGGVARYVCQEGFESPGGKITSV 280
+ G C+EG+ G V
Sbjct: 988 SP----GSYTCLACEEGYRGQSGSCVDV 1011
Score = 66.2 bits (160), Expect = 1e-10
Identities = 57/193 (29%), Positives = 78/193 (40%), Gaps = 36/193 (18%)
Query: 35 GLDVCATCHEHATCQQREGKKICI--CNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCH 92
G VC T C+ G C+ C GF C+D +EC +CG+H C
Sbjct: 1267 GDPVCGTWK----CENSPGSYRCVLGCQPGFHMAPNGDCIDIDEC--ANDTMCGSHGFCD 1320
Query: 93 NTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYC 152
NT G F C+C +G+ I G C D++ECE+ C N GSF C C
Sbjct: 1321 NTDGSFRCLCDQGFE--------ISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLC 1372
Query: 153 ---------MDGYL-PRN-GPEPFH--PTTD-ATSCTEIDC--GTPPEVPDGYIIGNYTS 196
+G+ PR G + PT D A + T +DC G P ++G T
Sbjct: 1373 ASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNT- 1431
Query: 197 SLGSQVRYACREG 209
+Q C +G
Sbjct: 1432 ---TQAECCCTQG 1441
Score = 57.8 bits (138), Expect = 4e-08
Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 20/122 (16%)
Query: 37 DVCATCHEHATCQQREGKKICICNYGFVGN------GRTQCVDKNECQFGATLVCGNHTS 90
D C C + + E IC G++ G+T D +EC +C N
Sbjct: 1446 DACDLCPSEDSAEFSE---ICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGR- 1501
Query: 91 CHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFEC 150
C NT G+ C+C G+ ++K C D DEC+ L G CVNT GSF C
Sbjct: 1502 CLNTVPGYVCLCNPGFHYDASHKK--------CEDHDECQ--DLACENGECVNTEGSFHC 1551
Query: 151 YC 152
+C
Sbjct: 1552 FC 1553
Score = 52.0 bits (123), Expect = 2e-06
Identities = 33/105 (31%), Positives = 47/105 (44%), Gaps = 22/105 (20%)
Query: 62 GFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGT 121
GF G +C N C+ G C G+ C C EG++ +
Sbjct: 1728 GFEGLQAEECGILNGCENGR---------CVRVREGYTCDCFEGFQLDAAHMA------- 1771
Query: 122 FCTDIDECE-VSG---LCRHGGRCVNTHGSFECYCMDGYLPRNGP 162
C D++EC+ ++G LC HG C NT GS+ C+C GY+ GP
Sbjct: 1772 -CVDVNECDDLNGPAVLCVHG-YCENTEGSYRCHCSPGYVAEAGP 1814
Score = 42.7 bits (99), Expect = 0.001
Identities = 22/56 (39%), Positives = 28/56 (50%), Gaps = 10/56 (17%)
Query: 102 CLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYL 157
C +GY+ N T C DI+EC GLC+ CVNT GS+ C C G +
Sbjct: 608 CPQGYKRLNL---------THCQDINECLTLGLCKDA-ECVNTRGSYLCTCRPGLM 653
Score = 40.4 bits (93), Expect = 0.006
Identities = 38/134 (28%), Positives = 52/134 (38%), Gaps = 28/134 (20%)
Query: 30 APGPDGLDVCATCHEHATCQQREGKKI----CICNYGFV-GNGRTQCVDKNECQFGATLV 84
AP P +D + HA C G+ C C G G+ C ++ +F +
Sbjct: 1405 APAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSE--I 1462
Query: 85 CGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEV--SGLCRHGGRCV 142
C P G +GY TF T TD DEC + GLC +G RC+
Sbjct: 1463 C---------PSG------KGYIPVEGAWTF---GQTMYTDADECVIFGPGLCPNG-RCL 1503
Query: 143 NTHGSFECYCMDGY 156
NT + C C G+
Sbjct: 1504 NTVPGYVCLCNPGF 1517
Score = 34.7 bits (78), Expect = 0.33
Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 4/71 (5%)
Query: 35 GLDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNT 94
G+ +CA C E ++ C G+ T C D NEC TL C NT
Sbjct: 585 GVTLCAPCPPRPASPVIENGQL-ECPQGYKRLNLTHCQDINEC---LTLGLCKDAECVNT 640
Query: 95 PGGFYCICLEG 105
G + C C G
Sbjct: 641 RGSYLCTCRPG 651
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 87.4 bits (215), Expect = 4e-17
Identities = 52/147 (35%), Positives = 73/147 (49%), Gaps = 18/147 (12%)
Query: 15 LPLLLLLGLARGAAGAPGPDGLDVCA----TCHEHATCQQREGKKICICNYGFVGNGRTQ 70
L LL+LL AR A + +D C CH A CQ CIC G+ G+G+
Sbjct: 9 LCLLVLLVHARAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGK-H 67
Query: 71 CVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDEC- 129
C D +EC+ C + C N PG + C C +G+ + +DG C D+DEC
Sbjct: 68 CKDVDECEREDNAGCVH--DCVNIPGNYRCTCYDGFH--------LAHDGHNCLDVDECA 117
Query: 130 EVSGLCRHGGRCVNTHGSFECYCMDGY 156
E +G C+ CVN GS+EC+C +G+
Sbjct: 118 EGNGGCQQS--CVNMMGSYECHCREGF 142
Score = 69.3 bits (168), Expect = 1e-11
Identities = 44/117 (37%), Positives = 52/117 (44%), Gaps = 20/117 (17%)
Query: 42 CHEHATCQQREGKKICICNYGFVGN-GRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYC 100
CH+ AT C C GF+ R C D +EC+ G C NT G F C
Sbjct: 251 CHDAATGVH------CTCPVGFMLQPDRKTCKDIDECRLNNG---GCDHICRNTVGSFEC 301
Query: 101 ICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYL 157
C +GY+ N + C DIDEC C H CVNT GSF+C C GYL
Sbjct: 302 SCKKGYKLLINERN--------CQDIDECSFDRTCDH--ICVNTPGSFQCLCHRGYL 348
Score = 65.5 bits (158), Expect = 2e-10
Identities = 46/125 (36%), Positives = 59/125 (47%), Gaps = 21/125 (16%)
Query: 48 CQQREGKKICICNYGF--VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEG 105
C+ G C C G+ + N R C D +EC F T +H C NTPG F C+C G
Sbjct: 292 CRNTVGSFECSCKKGYKLLINERN-CQDIDECSFDRTC---DHI-CVNTPGSFQCLCHRG 346
Query: 106 YRATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRCVNTHGSFECYCM--DGYLPRNGP 162
Y T C D+DEC ++ G CR G C+NT GS++C C G L NG
Sbjct: 347 YLLYGI---------THCGDVDECSINRGGCRFG--CINTPGSYQCTCPAGQGRLHWNGK 395
Query: 163 EPFHP 167
+ P
Sbjct: 396 DCTEP 400
Score = 62.4 bits (150), Expect = 1e-09
Identities = 68/228 (29%), Positives = 89/228 (39%), Gaps = 34/228 (14%)
Query: 47 TCQQREGKKICICNYGFV--GNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLE 104
TC E C C+ FV +G+T C++ G G + CH+ G +C C
Sbjct: 211 TCDDTEQGPRCGCHIKFVLHTDGKT-CIETCAVNNG-----GCDSKCHDAATGVHCTCPV 264
Query: 105 GYRATNNNKTFIPNDGTFCTDIDECEV-SGLCRHGGRCVNTHGSFECYCMDGYL----PR 159
G+ + KT C DIDEC + +G C H C NT GSFEC C GY R
Sbjct: 265 GFMLQPDRKT--------CKDIDECRLNNGGCDH--ICRNTVGSFECSCKKGYKLLINER 314
Query: 160 NGPEPFHPTTDATSCTEIDCGTPPEVP----DGYIIGNYTS----SLGSQVRYACREGFF 211
N + + D T C I TP GY++ T S R CR G
Sbjct: 315 NCQDIDECSFDRT-CDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCI 373
Query: 212 SVPEDTVSSC-TGLGTWESPKLHCQE-INCGNPPEMRHAILVGNHSSR 257
+ P +C G G C E + C P A+L N S +
Sbjct: 374 NTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPGASKAMLSCNRSGK 421
Score = 43.5 bits (101), Expect = 7e-04
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 15/100 (15%)
Query: 36 LDVCA---TCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCH 92
+D C+ TC C G C+C+ G++ G T C D +EC G C
Sbjct: 319 IDECSFDRTCDH--ICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRG---GCRFGCI 373
Query: 93 NTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS 132
NTPG + C C G + N G CT+ +C+ S
Sbjct: 374 NTPGSYQCTCPAGQGRLHWN-------GKDCTEPLKCQGS 406
Score = 32.7 bits (73), Expect = 1.3
Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 11/91 (12%)
Query: 32 GPDGLDVCATCHEHATCQQR----EGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCG 86
G + LDV + CQQ G C C GF + + + C+ + E G +
Sbjct: 107 GHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPE--EGMNCMNK 164
Query: 87 NHTS---CHNTP-GGFYCICLEGYRATNNNK 113
NH C TP GG C C G+ T N +
Sbjct: 165 NHGCAHICRETPKGGIACECRPGFELTKNQR 195
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 86.7 bits (213), Expect = 7e-17
Identities = 68/216 (31%), Positives = 88/216 (40%), Gaps = 45/216 (20%)
Query: 41 TCHEHATCQQR----EGKKICIC--NYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNT 94
TC ++ C+Q G IC C Y + +G C D++EC GA C C NT
Sbjct: 682 TCKDNGPCKQVCSTVGGSAICSCFPGYAIMADG-VSCEDQDECLMGAH-DCSRRQFCVNT 739
Query: 95 PGGFYCI-----CLEGYRATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRCVNTHGSF 148
G FYC+ C +GY + K C DI+EC C G CVNT GSF
Sbjct: 740 LGSFYCVNHTVLCADGYILNAHRK---------CVDINECVTDLHTCSRGEHCVNTLGSF 790
Query: 149 ECY----CMDGYLPRNGPEPFHPTTDATSCTEID---CGTPPEVPDGYIIGNYTSSLGSQ 201
CY C GY ++G C ++D GT P G++ N S Q
Sbjct: 791 HCYKALTCEPGYALKDG-----------ECEDVDECAMGTHTCQP-GFLCQNTKGSFYCQ 838
Query: 202 VRYACREGFFSVPEDT---VSSCTGLGTWESPKLHC 234
R C +GF PE ++ CT L P C
Sbjct: 839 ARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSC 874
Score = 75.9 bits (185), Expect = 1e-13
Identities = 48/140 (34%), Positives = 60/140 (42%), Gaps = 25/140 (17%)
Query: 42 CHEHATCQQREGKKICICNYGF----VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGG 97
C E C G C C GF G G C+D NEC +C HT C NT G
Sbjct: 916 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRG---CIDVNECWASPGRLC-QHT-CENTLGS 970
Query: 98 FYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGY- 156
+ C C G+ + DG C D++ECE R C N +GS++CYC GY
Sbjct: 971 YRCSCASGF--------LLAADGKRCEDVNECEAQ---RCSQECANIYGSYQCYCRQGYQ 1019
Query: 157 LPRNGPEPFHPTTDATSCTE 176
L +G H TD C +
Sbjct: 1020 LAEDG----HTCTDIDECAQ 1035
Score = 65.1 bits (157), Expect = 2e-10
Identities = 43/134 (32%), Positives = 60/134 (44%), Gaps = 24/134 (17%)
Query: 47 TCQQREGKKICICNYGFV--GNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLE 104
TC+ G C C GF+ +G+ +C D NEC+ C C N G + C C +
Sbjct: 963 TCENTLGSYRCSCASGFLLAADGK-RCEDVNECEAQR---CSQE--CANIYGSYQCYCRQ 1016
Query: 105 GYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEP 164
GY+ + DG CTDIDEC RC+N GS++C C P G
Sbjct: 1017 GYQ--------LAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCAC-----PEQG--- 1060
Query: 165 FHPTTDATSCTEID 178
+ T + SC ++D
Sbjct: 1061 YTMTANGRSCKDVD 1074
Score = 62.8 bits (151), Expect = 1e-09
Identities = 58/188 (30%), Positives = 76/188 (40%), Gaps = 45/188 (23%)
Query: 70 QCVDKNECQFGATLVCGNHTSCHNTPGGFYCI----CLEGYRATNNNKTFIPNDGTFCTD 125
+C D +EC G T C C NT G FYC C++G F+ + C D
Sbjct: 808 ECEDVDECAMG-THTCQPGFLCQNTKGSFYCQARQRCMDG---------FLQDPEGNCVD 857
Query: 126 IDEC-EVSGLCRHGGRCVNTHGSFEC-----YCMDGYLPRNGPEPFHPTTDATSCTEI-D 178
I+EC +S CR G C+NT GS+ C C GY H + D T C ++ +
Sbjct: 858 INECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGY---------HASDDGTKCVDVNE 908
Query: 179 CGT-PPEVPDGYIIGNYTSSLGSQVRYACREGF----FSVPEDTVSSCTGLGTWESPKLH 233
C T +G + N L R C+ GF F V+ C W SP
Sbjct: 909 CETGVHRCGEGQVCHN----LPGSYRCDCKAGFQRDAFGRGCIDVNEC-----WASPGRL 959
Query: 234 CQEINCGN 241
CQ C N
Sbjct: 960 CQH-TCEN 966
Score = 60.1 bits (144), Expect = 7e-09
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 18/141 (12%)
Query: 48 CQQREGKKICICNYGF--VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLE- 104
C G C C G+ +G T C D +EC GA ++C C N PG + C C E
Sbjct: 1003 CANIYGSYQCYCRQGYQLAEDGHT-CTDIDECAQGAGILCTFR--CLNVPGSYQCACPEQ 1059
Query: 105 GYRATNNNKTFIPNDGTFCTDIDECEV-SGLCRHGGRCVNTHGSFECYCMDGYLPRNGPE 163
GY T N ++ C D+DEC + + C C N GSF C + P N +
Sbjct: 1060 GYTMTANGRS--------CKDVDECALGTHNCSEAETCHNIQGSFRCLRFE--CPPNYVQ 1109
Query: 164 PFHPTTDATSCTE-IDCGTPP 183
+ T+C + ++C P
Sbjct: 1110 VSKTKCERTTCHDFLECQNSP 1130
Score = 31.6 bits (70), Expect = 2.8
Identities = 15/34 (44%), Positives = 20/34 (58%), Gaps = 4/34 (11%)
Query: 125 DIDECEV--SGLCRHGGRCVNTHGSFECYCMDGY 156
D DEC + LC+H C+NT GS+ C C G+
Sbjct: 604 DQDECLLLPGELCQH--LCINTVGSYHCACFPGF 635
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 85.9 bits (211), Expect = 1e-16
Identities = 55/186 (29%), Positives = 80/186 (43%), Gaps = 30/186 (16%)
Query: 57 CICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFI 116
C CN G+ + R +C+D +EC +H C N PG ++C C G++AT +
Sbjct: 433 CECNVGYTQDVRGECIDVDECTSSPC----HHGDCVNIPGTYHCRCYPGFQATPTRQA-- 486
Query: 117 PNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTE 176
C D+DEC VSG H GRCVNT GSF+C C G F + D +C +
Sbjct: 487 ------CVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAG---------FELSPDGKNCVD 531
Query: 177 -IDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQ 235
+C T +G + C+ GF P C + ++P + C
Sbjct: 532 HNECATSTMCVNGVCLNE-----DGSFSCLCKPGFLLAPGG--HYCMDIDECQTPGI-CV 583
Query: 236 EINCGN 241
+C N
Sbjct: 584 NGHCTN 589
Score = 85.9 bits (211), Expect = 1e-16
Identities = 67/237 (28%), Positives = 99/237 (41%), Gaps = 49/237 (20%)
Query: 42 CHEHATCQQREGKKICICNYGF--VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFY 99
C H C EG C C G+ + +GR C D +EC+ + H C N PGG
Sbjct: 1166 CDVH--CINTEGSYRCSCGQGYSLMPDGRA-CADVDECEENPRVCDQGH--CTNMPGGHR 1220
Query: 100 CICLEGYRATNNNKTFIPNDGTFCTDIDECEVSG-LCRHGGRCVNTHGSFECYCMDGYLP 158
C+C +G+ AT + +T C D+DEC+++ +C HG C NT GSF C+C GY+
Sbjct: 1221 CLCYDGFMATPDMRT--------CVDVDECDLNPHICLHGD-CENTKGSFVCHCQLGYMV 1271
Query: 159 RNGPEPFHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDT 217
R G AT C+++D C G+ ++ S L ++CR
Sbjct: 1272 RKG---------ATGCSDVDECEV-----GGHNCDSHASCLNIPGSFSCR---------- 1307
Query: 218 VSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPG 274
C L W C +++ H + G R C++GF G
Sbjct: 1308 ---C--LPGWVGDGFECHDLD--ECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDG 1357
Score = 85.5 bits (210), Expect = 2e-16
Identities = 76/264 (28%), Positives = 108/264 (40%), Gaps = 73/264 (27%)
Query: 45 HATCQQREGKKICICNYGFVGNGRTQ-CVDKNECQFGATLVCGNHTSCHNTPGGFYCICL 103
H TC+ G C C GF + + + C D +EC+ L CG T C NTPG F C C
Sbjct: 999 HGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDL-CGQGT-CVNTPGSFECECF 1056
Query: 104 EGYRA--------------------------TNNNKTF---------IPNDGTFCTDIDE 128
GY + TN + ++ + GT C DIDE
Sbjct: 1057 PGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDE 1116
Query: 129 CEVS-GLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEI-DCGTPPEVP 186
C +S GLC H G+CVN G+F+C C G F T D C +I +C V
Sbjct: 1117 CSLSDGLCPH-GQCVNVIGAFQCSCHAG---------FQSTPDRQGCVDINEC----RVQ 1162
Query: 187 DGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMR 246
+G + ++ GS R +C +G+ +P+ +C + E C + +C N P
Sbjct: 1163 NGGCDVHCINTEGS-YRCSCGQGYSLMPDG--RACADVDECEENPRVCDQGHCTNMP--- 1216
Query: 247 HAILVGNHSSRLGGVARYVCQEGF 270
G H R +C +GF
Sbjct: 1217 -----GGH--------RCLCYDGF 1227
Score = 82.0 bits (201), Expect = 2e-15
Identities = 48/135 (35%), Positives = 63/135 (46%), Gaps = 26/135 (19%)
Query: 45 HATCQQREGKKICICNYGFVGNG-RTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICL 103
H C EG +C+C+ GF + +T C+D +EC CGN T C N G + C+C
Sbjct: 1818 HGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECD---RQPCGNGT-CKNIIGSYNCLCF 1873
Query: 104 EGYRATNNNKTFIPNDGTFCTDIDECE--VSGLCRHGGRCVNTHGSFECYCMDGYLPRNG 161
G+ T+N C D DEC V +CR G C+NT GSF C C DG
Sbjct: 1874 PGFVVTHNGD---------CVDFDECTTLVGQVCRFG-HCLNTAGSFHCLCQDG------ 1917
Query: 162 PEPFHPTTDATSCTE 176
F T D +C +
Sbjct: 1918 ---FELTADGKNCVD 1929
Score = 80.1 bits (196), Expect = 7e-15
Identities = 44/115 (38%), Positives = 54/115 (46%), Gaps = 14/115 (12%)
Query: 42 CHEHATCQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYC 100
CH C EG C+CN GF + CVD NEC V G C N G F C
Sbjct: 500 CHL-GRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNG---VCLNEDGSFSC 555
Query: 101 ICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDG 155
+C G+ + G +C DIDEC+ G+C +G C NT GSF C C+ G
Sbjct: 556 LCKPGF--------LLAPGGHYCMDIDECQTPGICVNG-HCTNTEGSFRCQCLGG 601
Score = 79.3 bits (194), Expect = 1e-14
Identities = 52/155 (33%), Positives = 67/155 (43%), Gaps = 27/155 (17%)
Query: 29 GAPGPDGLDVCAT----CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLV 84
GA G +D C C HA+C G C C G+VG+G +C D +EC
Sbjct: 1274 GATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDG-FECHDLDEC-VSQEHR 1331
Query: 85 CGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLCRHGGRCVN 143
C C N PG + C C +G+ DG FC D DEC E LC G+C+N
Sbjct: 1332 CSPRGDCLNVPGSYRCTCRQGFAG----------DGFFCEDRDECAENVDLC-DNGQCLN 1380
Query: 144 THGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID 178
G + C C G F PT D +C ++D
Sbjct: 1381 APGGYRCECEMG---------FDPTEDHRACQDVD 1406
Score = 71.6 bits (174), Expect = 2e-12
Identities = 47/139 (33%), Positives = 57/139 (41%), Gaps = 23/139 (16%)
Query: 31 PGPDGLDVCAT---------CHEHATCQQREGKKICICNYGFVG----NGRTQCVDKNEC 77
PG +DVC C + E +C GF +GR D NEC
Sbjct: 931 PGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNEC 990
Query: 78 QFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRH 137
+ L H +C NT G F+C C G+ + CTDIDEC +S
Sbjct: 991 KVFPGLC--THGTCRNTVGSFHCACAGGFALDAQERN--------CTDIDECRISPDLCG 1040
Query: 138 GGRCVNTHGSFECYCMDGY 156
G CVNT GSFEC C GY
Sbjct: 1041 QGTCVNTPGSFECECFPGY 1059
Score = 71.6 bits (174), Expect = 2e-12
Identities = 44/134 (32%), Positives = 54/134 (40%), Gaps = 17/134 (12%)
Query: 48 CQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C EG +C C G+ + C D +EC G C N G F C+C G
Sbjct: 2181 CHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGM 2240
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFH 166
R +P G CTD +EC GRCVNT GSF C C +G F
Sbjct: 2241 RP-------LPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEG---------FQ 2284
Query: 167 PTTDATSCTEIDCG 180
P+ T C +I G
Sbjct: 2285 PSPTLTECHDIRQG 2298
Score = 71.2 bits (173), Expect = 3e-12
Identities = 72/257 (28%), Positives = 95/257 (36%), Gaps = 54/257 (21%)
Query: 26 GAAGAPGPDG----LDVCA----TCHEHATCQQREGKKICICNYGF-VGNGRTQCVDKNE 76
G PGPD ++ CA C + C +G C C +G+ + CVD +E
Sbjct: 2071 GHGAVPGPDDSREDVNECAENPGVC-TNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDE 2129
Query: 77 CQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL-C 135
C G CG T C N GGF C C +G+ P C DIDEC ++ L C
Sbjct: 2130 CSVGHP--CGQGT-CTNVIGGFECACADGFE---------PGLMMTCEDIDECSLNPLLC 2177
Query: 136 RHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPDGYIIGNY 194
RC NT GS+ C C GY R D C ++D C + D + G
Sbjct: 2178 AF--RCHNTEGSYLCTCPAGYTLRE---------DGAMCRDVDECADGQQ--DCHARGME 2224
Query: 195 TSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNH 254
+L C G +P +G G + + H Q C V
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPG------SGEGCTDDNECHAQPDLC-----------VNGR 2267
Query: 255 SSRLGGVARYVCQEGFE 271
G R C EGF+
Sbjct: 2268 CVNTAGSFRCDCDEGFQ 2284
Score = 70.1 bits (170), Expect = 7e-12
Identities = 40/123 (32%), Positives = 55/123 (44%), Gaps = 14/123 (11%)
Query: 36 LDVCATCHEHAT--CQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHN 93
LD C + + C G C C GF + + C D +EC CG H CHN
Sbjct: 2447 LDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQA-CFDNDECS-AQPGPCGAHGHCHN 2504
Query: 94 TPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCM 153
TPG F C C +G+ + + G C D++EC+ C+HG C N G + C C
Sbjct: 2505 TPGSFRCECHQGFT--------LVSSGHGCEDVNECDGPHRCQHG--CQNQLGGYRCSCP 2554
Query: 154 DGY 156
G+
Sbjct: 2555 QGF 2557
Score = 69.7 bits (169), Expect = 9e-12
Identities = 50/169 (29%), Positives = 69/169 (40%), Gaps = 35/169 (20%)
Query: 45 HATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLE 104
+ TC+ G C+C GFV CVD +EC VC C NT G F+C+C +
Sbjct: 1858 NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVC-RFGHCLNTAGSFHCLCQD 1916
Query: 105 GYRATNNNK-------------TFIPN-----DGTF--------------CTDIDEC-EV 131
G+ T + K T +P +G+F C DIDEC E
Sbjct: 1917 GFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEE 1976
Query: 132 SGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCG 180
LC G C N+ GSF+C C G++ + T + T + G
Sbjct: 1977 PNLCLFG-TCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAG 2024
Score = 68.2 bits (165), Expect = 3e-11
Identities = 40/128 (31%), Positives = 60/128 (46%), Gaps = 16/128 (12%)
Query: 34 DGLDVCAT----CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHT 89
+ +D C + C ++A C G C C G+ + CV +NEC+ VC +H
Sbjct: 1762 EDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECR-EIPNVC-SHG 1819
Query: 90 SCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFE 149
C +T G + C+C G++A+ D T C DIDEC+ G C N GS+
Sbjct: 1820 DCMDTEGSYMCLCHRGFQAS--------ADQTLCMDIDECDRQPC--GNGTCKNIIGSYN 1869
Query: 150 CYCMDGYL 157
C C G++
Sbjct: 1870 CLCFPGFV 1877
Score = 66.2 bits (160), Expect = 1e-10
Identities = 48/151 (31%), Positives = 64/151 (42%), Gaps = 26/151 (17%)
Query: 52 EGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNN 111
E + +C G +GR D NEC VC N C N G + C+C GY A +
Sbjct: 665 EFQALCSSGLGITTDGR----DINECALDPE-VCANGV-CENLRGSYRCVCNLGYEAGAS 718
Query: 112 NKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDA 171
K CTD+DEC ++ L G C N+ GS+ C C P FH D
Sbjct: 719 GKD--------CTDVDECALNSLLCDNGWCQNSPGSYSCSC---------PPGFHFWQDT 761
Query: 172 TSCTEID-CGTPPEVPD--GYIIGNYTSSLG 199
C ++D C + P V + G+YT G
Sbjct: 762 EICKDVDECLSSPCVSGVCRNLAGSYTCKCG 792
Score = 66.2 bits (160), Expect = 1e-10
Identities = 43/111 (38%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 48 CQQREGKKICICNYGFVGNGR-TQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
CQ + G C C GF + + QCVD+NEC CG+ SC NT GGF C+C G+
Sbjct: 2542 CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPP-TCGS-ASCRNTLGGFRCVCPSGF 2599
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRCVNTHGSFECYCMDGY 156
F G C ++DEC G C + C NT G F C C GY
Sbjct: 2600 -------DFDQALGG-CQEVDECAGRRGPCSYS--CANTPGGFLCGCPQGY 2640
Score = 63.5 bits (153), Expect = 7e-10
Identities = 41/124 (33%), Positives = 55/124 (44%), Gaps = 25/124 (20%)
Query: 37 DVCATCHEHATCQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCHNTP 95
+VCA + C+ G C+CN G+ G C D +EC +L+C N C N+P
Sbjct: 691 EVCA----NGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALN-SLLCDNGW-CQNSP 744
Query: 96 GGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECE----VSGLCRHGGRCVNTHGSFECY 151
G + C C G+ D C D+DEC VSG+CR N GS+ C
Sbjct: 745 GSYSCSCPPGFH--------FWQDTEICKDVDECLSSPCVSGVCR------NLAGSYTCK 790
Query: 152 CMDG 155
C G
Sbjct: 791 CGPG 794
Score = 63.2 bits (152), Expect = 9e-10
Identities = 45/148 (30%), Positives = 58/148 (39%), Gaps = 26/148 (17%)
Query: 34 DGLDVCATCHEHATCQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCH 92
+ +D+C ++ C G C C GF C D +EC G G SC
Sbjct: 1368 ENVDLC----DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG---SCE 1420
Query: 93 NTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYC 152
N PG F CIC GY + G CTDI+EC C + G C+NT GS+ C C
Sbjct: 1421 NLPGMFRCICNGGYE--------LDRGGGNCTDINECADPVNCIN-GVCINTPGSYLCSC 1471
Query: 153 MDGYLPRNGPEPFHPTTDATSCTEIDCG 180
P+ F C + G
Sbjct: 1472 ---------PQDFELNPSGVGCVDTRAG 1490
Score = 62.4 bits (150), Expect = 1e-09
Identities = 66/231 (28%), Positives = 90/231 (38%), Gaps = 54/231 (23%)
Query: 45 HATCQQREGKKICICNYGFVGNGR-TQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICL 103
H C G C C G+ + T C+D +EC C C NT G F C C
Sbjct: 2376 HGECINSLGSFRCHCQAGYTPDATATTCLDMDECS-QVPKPCT--FLCKNTKGSFLCSCP 2432
Query: 104 EGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGR--CVNTHGSFECYCMDGYLPRNG 161
GY + DG C D+DEC +H + CVNT G+F C C G+
Sbjct: 2433 RGY--------LLEEDGRTCKDLDECTSR---QHNCQFLCVNTVGAFTCRCPPGF----- 2476
Query: 162 PEPFHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSS 220
T +C + D C P + G+ ++ GS R C +GF VSS
Sbjct: 2477 ------TQHHQACFDNDECSAQPGPCGAH--GHCHNTPGS-FRCECHQGF-----TLVSS 2522
Query: 221 CTGLGTWESPKLHCQEIN-CGNPPEMRHAILVGNHSSRLGGVARYVCQEGF 270
G C+++N C P +H ++LGG R C +GF
Sbjct: 2523 GHG----------CEDVNECDGPHRCQHGC-----QNQLGGY-RCSCPQGF 2557
Score = 62.0 bits (149), Expect = 2e-09
Identities = 44/128 (34%), Positives = 51/128 (39%), Gaps = 14/128 (10%)
Query: 31 PGPDGLDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTS 90
PG D C C + + +E +C +G V D NEC VC N
Sbjct: 2045 PGEGWGDPCELCPQEGSAAFQE---LCPFGHGAVPGPDDSREDVNECAENPG-VCTNGV- 2099
Query: 91 CHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFEC 150
C NT G F C C GY + G C D DEC V C G C N G FEC
Sbjct: 2100 CVNTDGSFRCECPFGYS--------LDFTGINCVDTDECSVGHPCGQG-TCTNVIGGFEC 2150
Query: 151 YCMDGYLP 158
C DG+ P
Sbjct: 2151 ACADGFEP 2158
Score = 56.6 bits (135), Expect = 8e-08
Identities = 41/112 (36%), Positives = 51/112 (45%), Gaps = 13/112 (11%)
Query: 52 EGKKICICNYGFVGNGRTQCV-DKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATN 110
E + +C GF N T + D +ECQ L G C NT G F C C GY +
Sbjct: 1541 EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGG--DCVNTFGSFQCECPPGYHLSE 1598
Query: 111 NNKTFIPNDGTFCTDIDECEV-SGLCRHGGRCVNTHGSFECYCMDGYLPRNG 161
+ + C DIDEC SG+C G C NT G++ C C YL NG
Sbjct: 1599 HTR--------ICEDIDECSTHSGIC-GPGTCYNTLGNYTCVCPAEYLQVNG 1641
Score = 54.3 bits (129), Expect = 4e-07
Identities = 46/131 (35%), Positives = 56/131 (42%), Gaps = 23/131 (17%)
Query: 42 CHEHATCQQREGKKICICNYGFVGNGRTQC------------VDKNECQFGATLVCGNHT 89
CH C G C C YGF+G QC V CQ T +
Sbjct: 155 CHNGGRCI---GPNRCACVYGFMG---PQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKA 208
Query: 90 SCHNTPGGFYCICLEGYRATNN--NKTFIPNDGT-FCTDIDECE-VSGLCRHGGRCVNTH 145
C T G + + E A + + FIPN T C D+DEC+ V GLC+ GG CVN
Sbjct: 209 LCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQ-GGSCVNMV 267
Query: 146 GSFECYCMDGY 156
GSF C C G+
Sbjct: 268 GSFHCRCPVGH 278
Score = 48.1 bits (113), Expect = 3e-05
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 19/113 (16%)
Query: 125 DIDECEV-SGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTP 182
D+DEC + + LC HG C+N+ GSF C+C GY P AT+C ++D C
Sbjct: 2363 DVDECRMLAHLCAHG-ECINSLGSFRCHCQAGYT---------PDATATTCLDMDECSQV 2412
Query: 183 PEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQ 235
P+ P ++ N S +C G+ + E+ +C L S + +CQ
Sbjct: 2413 PK-PCTFLCKNTKGSF----LCSCPRGY--LLEEDGRTCKDLDECTSRQHNCQ 2458
Score = 47.8 bits (112), Expect = 4e-05
Identities = 32/70 (45%), Positives = 37/70 (52%), Gaps = 13/70 (18%)
Query: 115 FIPNDGT-FCTDIDEC-EVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDAT 172
F PN T DIDEC E+ GLC+ GG CVNT GSF+C C GY H +
Sbjct: 1552 FQPNRITVILEDIDECQELPGLCQ-GGDCVNTFGSFQCECPPGY---------HLSEHTR 1601
Query: 173 SCTEID-CGT 181
C +ID C T
Sbjct: 1602 ICEDIDECST 1611
Score = 44.7 bits (104), Expect = 3e-04
Identities = 52/192 (27%), Positives = 66/192 (34%), Gaps = 67/192 (34%)
Query: 28 AGAPGPDGLDV--CATCH---EHATCQQREGKKICICNYGFVGNGRTQ-CVDKNECQFGA 81
AGA G D DV CA ++ CQ G C C GF T+ C D +EC +
Sbjct: 715 AGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSS 773
Query: 82 TLVCGNHTSCHNTPGGFYC-------------ICLEGYRATNNNKT-------------- 114
V G C N G + C CL+ + T K
Sbjct: 774 PCVSG---VCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASL 830
Query: 115 ----------------------------FIPNDGTFCTDIDECE-VSGLCRHGGRCVNTH 145
F G C D++ECE G+C +G RCVNT
Sbjct: 831 RSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNG-RCVNTA 889
Query: 146 GSFECYCMDGYL 157
GSF C C +G +
Sbjct: 890 GSFRCECPEGLM 901
Score = 41.2 bits (95), Expect = 0.004
Identities = 53/189 (28%), Positives = 69/189 (36%), Gaps = 41/189 (21%)
Query: 47 TCQQREGKKICICNYGFV--GNGRTQCVDKNECQFGATLVCGN------------HTSCH 92
TC G C+C GFV NG +C D + G C
Sbjct: 1984 TCTNSPGSFQCLCPPGFVLSDNGH-RCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCS 2042
Query: 93 NTPG---GFYC-IC-LEGYRATNNNKTF----IPNDGTFCTDIDEC-EVSGLCRHGGRCV 142
PG G C +C EG A F +P D++EC E G+C +G CV
Sbjct: 2043 KRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGV-CV 2101
Query: 143 NTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYT-SSLGSQ 201
NT GSF C C GY + T I+C E G+ G T +++
Sbjct: 2102 NTDGSFRCECPFGY--------------SLDFTGINCVDTDECSVGHPCGQGTCTNVIGG 2147
Query: 202 VRYACREGF 210
AC +GF
Sbjct: 2148 FECACADGF 2156
Score = 39.7 bits (91), Expect = 0.010
Identities = 24/62 (38%), Positives = 30/62 (48%), Gaps = 4/62 (6%)
Query: 46 ATCQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLE 104
A+C+ G C+C GF C + +EC G C SC NTPGGF C C +
Sbjct: 2582 ASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECA-GRRGPCSY--SCANTPGGFLCGCPQ 2638
Query: 105 GY 106
GY
Sbjct: 2639 GY 2640
Score = 39.3 bits (90), Expect = 0.013
Identities = 35/114 (30%), Positives = 46/114 (40%), Gaps = 22/114 (19%)
Query: 59 CNYGFVGNGRT-QCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIP 117
C GF+ N T C D +ECQ L G SC N G F+C C G+R ++++
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGG--SCVNMVGSFHCRCPVGHRLSDSSAA--- 286
Query: 118 NDGTFCTDIDECEVSGLC---RHGGRCVNT----HGSFECYCMDGYLPRNGPEP 164
C D +G C GGRC + +C C G GP P
Sbjct: 287 -----CEDYR----AGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVP 331
Score = 35.8 bits (81), Expect = 0.15
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 12/59 (20%)
Query: 125 DIDEC-EVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGT 181
DIDEC E+ +C +G C+N GSF C C P F+ + +C ++D CG+
Sbjct: 1721 DIDECGEIPAICANG-ICINQIGSFRCEC---------PAGFNYNSILLACEDVDECGS 1769
Score = 33.5 bits (75), Expect = 0.74
Identities = 27/85 (31%), Positives = 31/85 (36%), Gaps = 21/85 (24%)
Query: 59 CNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPN 118
C GF C D NEC+ VC N C NT G F C C EG +
Sbjct: 855 CARGFARMTGVTCDDVNECE-SFPGVCPNGR-CVNTAGSFRCECPEG--------LMLDA 904
Query: 119 DGTFCTDI-----------DECEVS 132
G C D+ DEC V+
Sbjct: 905 SGRLCVDVRLEPCFLRWDEDECGVT 929
Score = 33.5 bits (75), Expect = 0.74
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 3/77 (3%)
Query: 48 CQQREGKKICICNYGFVGNGRTQ-CVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C G C C G+ + T+ C D +EC + +CG T C+NT G + C+C Y
Sbjct: 1579 CVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSG-ICGPGT-CYNTLGNYTCVCPAEY 1636
Query: 107 RATNNNKTFIPNDGTFC 123
N + + C
Sbjct: 1637 LQVNGGNNCMDMRKSVC 1653
Score = 32.7 bits (73), Expect = 1.3
Identities = 24/81 (29%), Positives = 29/81 (35%), Gaps = 12/81 (14%)
Query: 134 LCRH------GGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDC--GTPPEV 185
+CRH GRC+ T S+ C C GY E D CT C G +
Sbjct: 411 ICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE----CIDVDECTSSPCHHGDCVNI 466
Query: 186 PDGYIIGNYTSSLGSQVRYAC 206
P Y Y + R AC
Sbjct: 467 PGTYHCRCYPGFQATPTRQAC 487
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 85.5 bits (210), Expect = 2e-16
Identities = 56/149 (37%), Positives = 66/149 (44%), Gaps = 26/149 (17%)
Query: 36 LDVCAT----CHEHATCQQREGKKICICNYGF-VGNGRT-QCVDKNECQFGATLVCGNHT 89
+D C++ C H C EG C C G+ +GR C D NEC G C H
Sbjct: 768 VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD--FCFPHG 825
Query: 90 SCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFE 149
C NT G F C C GYR G C D+DEC LC+ G C NT GSFE
Sbjct: 826 ECLNTDGSFACTCAPGYRPGPR--------GASCLDVDECSEEDLCQ-SGICTNTDGSFE 876
Query: 150 CYCMDGYLPRNGPEPFHPTTDATSCTEID 178
C C G+ R GP D SC ++D
Sbjct: 877 CICPPGH--RAGP-------DLASCLDVD 896
Score = 79.0 bits (193), Expect = 2e-14
Identities = 61/201 (30%), Positives = 72/201 (35%), Gaps = 62/201 (30%)
Query: 22 GLARGAAGAPGPDGLDVCATCHEHAT---CQQREGKKICICNYGFVGNG----------- 67
G GAP D +D CA T C+ EG C+C GF N
Sbjct: 673 GFRSRGPGAPCQD-VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC 731
Query: 68 ------------------------------RTQCVDKNECQFGATLVCGNHTSCHNTPGG 97
R +C D +EC GA CG H C NT G
Sbjct: 732 ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAP-PCGPHGHCTNTEGS 790
Query: 98 FYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYL 157
F C C GYRA + P C D++EC C G C+NT GSF C C GY
Sbjct: 791 FRCSCAPGYRAPSGR----PGP---CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYR 843
Query: 158 PRNGPEPFHPTTDATSCTEID 178
P GP SC ++D
Sbjct: 844 P--GPR-------GASCLDVD 855
Score = 75.1 bits (183), Expect = 2e-13
Identities = 52/163 (31%), Positives = 66/163 (40%), Gaps = 28/163 (17%)
Query: 32 GPDGL-DVCATCHEHAT-------CQQREGKKICI--CNYGFVGNGRTQCVDKNECQFGA 81
GP+G D C E+ C+ G C C+ G+ C D +EC+ +
Sbjct: 931 GPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRS 990
Query: 82 TLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECE-VSGLCRHGGR 140
CG H C N PG F C+C +GY DG C D++ECE + G+C
Sbjct: 991 --FCGAHAVCQNLPGSFQCLCDQGYEGAR--------DGRHCVDVNECETLQGVCG-AAL 1039
Query: 141 CVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPP 183
C N GSF C C N PE F P T GT P
Sbjct: 1040 CENVEGSFLCVC------PNSPEEFDPMTGRCVPPRTSAGTFP 1076
Score = 71.2 bits (173), Expect = 3e-12
Identities = 42/111 (37%), Positives = 53/111 (47%), Gaps = 13/111 (11%)
Query: 48 CQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C+ G C+C GF G +C+D +EC C + C NTPG F C+C GY
Sbjct: 536 CENSPGSFRCVCGPGFRAGPRAAECLDVDECH-RVPPPC-DLGRCENTPGSFLCVCPAGY 593
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRCVNTHGSFECYCMDGY 156
+A + G C D+DEC S GLC G C N GSF C C G+
Sbjct: 594 QAAPH--------GASCQDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGF 635
Score = 69.7 bits (169), Expect = 9e-12
Identities = 69/224 (30%), Positives = 88/224 (39%), Gaps = 38/224 (16%)
Query: 28 AGAPGPDGLDVCATCH------EHATCQQREGKKICICNYGFVGNGR-TQCVDKNECQFG 80
AG + LDV CH + C+ G +C+C G+ C D +EC
Sbjct: 553 AGPRAAECLDV-DECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQS 611
Query: 81 ATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFC-TDIDECEVSGLCRHGG 139
L CG +C N PG F C+C G+R G+ C D+DEC G
Sbjct: 612 PGL-CGRG-ACKNLPGSFRCVCPAGFR------------GSACEEDVDECAQEPPPCGPG 657
Query: 140 RCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLG 199
RC NT GSF C C G+ R P P D C +PP P Y G ++ G
Sbjct: 658 RCDNTAGSFHCACPAGFRSRG---PGAPCQDVDECAR----SPP--PCTY--GRCENTEG 706
Query: 200 SQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPP 243
S + C GF P S C + E+ L C C N P
Sbjct: 707 S-FQCVCPMGF--QPNTAGSECEDVDECEN-HLACPGQECVNSP 746
Score = 67.4 bits (163), Expect = 5e-11
Identities = 43/139 (30%), Positives = 54/139 (38%), Gaps = 19/139 (13%)
Query: 48 CQQREGKKICI--CNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI--CL 103
C+ G C+ C+ G+ C D +ECQ +CG C NTPG + C C
Sbjct: 911 CENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR-CENTPGSYRCTPACD 969
Query: 104 EGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPE 163
GY+ P G C D+DEC C C N GSF+C C GY G
Sbjct: 970 PGYQ---------PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGY---EGAR 1017
Query: 164 PFHPTTDATSCTEID--CG 180
D C + CG
Sbjct: 1018 DGRHCVDVNECETLQGVCG 1036
Score = 66.6 bits (161), Expect = 8e-11
Identities = 53/146 (36%), Positives = 67/146 (45%), Gaps = 27/146 (18%)
Query: 31 PGPDG---LDVCATCHEHATCQQ-----REGKKICICNYGF-VGNGRTQCVDKNECQFGA 81
PGP G LDV C E CQ +G CIC G G C+D +EC+
Sbjct: 844 PGPRGASCLDV-DECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERG 902
Query: 82 TLVCGNHTSCHNTPGGFYCI--CLEGYRATNNNKTFIPNDGTFCTDIDECEVSG--LCRH 137
+CG+ C N+PG + C+ C GY A +GT C D+DEC+ G +C
Sbjct: 903 PALCGSQ-RCENSPGSYRCVRDCDPGYHA--------GPEGT-CDDVDECQEYGPEIC-G 951
Query: 138 GGRCVNTHGSFEC--YCMDGYLPRNG 161
RC NT GS+ C C GY P G
Sbjct: 952 AQRCENTPGSYRCTPACDPGYQPTPG 977
Score = 66.2 bits (160), Expect = 1e-10
Identities = 60/195 (30%), Positives = 80/195 (41%), Gaps = 39/195 (20%)
Query: 26 GAAGAPGPDGLDVCAT----CHEHATCQQREGKKICICNYGFVGNGR-TQCVDKNECQFG 80
G G+ + +D CA C C G C C GF G C D +EC
Sbjct: 634 GFRGSACEEDVDECAQEPPPCGP-GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARS 692
Query: 81 ATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPND-GTFCTDIDECEVSGLCRHGG 139
+ C NT G F C+C G++ PN G+ C D+DECE C G
Sbjct: 693 PPPC--TYGRCENTEGSFQCVCPMGFQ---------PNTAGSECEDVDECENHLACP-GQ 740
Query: 140 RCVNTHGSFEC-YCMDGYLPRNGPEPFHPTTDATSCTEID---CGTPPEVPDGYIIGNYT 195
CVN+ GSF+C C G+ G CT++D G PP P G+ T
Sbjct: 741 ECVNSPGSFQCRTCPSGHHLHRG-----------RCTDVDECSSGAPPCGPHGHC----T 785
Query: 196 SSLGSQVRYACREGF 210
++ GS R +C G+
Sbjct: 786 NTEGS-FRCSCAPGY 799
Score = 56.2 bits (134), Expect = 1e-07
Identities = 58/192 (30%), Positives = 74/192 (38%), Gaps = 49/192 (25%)
Query: 84 VCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVN 143
VCG C + P G+ C C G+R + GT C D+DEC GRC N
Sbjct: 488 VCGPGR-CISRPSGYTCACDSGFR--------LSPQGTRCIDVDECRRVPPPCAPGRCEN 538
Query: 144 THGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQV 202
+ GSF C C G+ R GP A C ++D C P D +G ++ GS +
Sbjct: 539 SPGSFRCVCGPGF--RAGPR-------AAECLDVDECHRVPPPCD---LGRCENTPGSFL 586
Query: 203 RYACREGFFSVPE----DTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRL 258
C G+ + P V CT +SP L C C N P
Sbjct: 587 -CVCPAGYQAAPHGASCQDVDECT-----QSPGL-CGRGACKNLP--------------- 624
Query: 259 GGVARYVCQEGF 270
G R VC GF
Sbjct: 625 -GSFRCVCPAGF 635
Score = 55.1 bits (131), Expect = 2e-07
Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 13/81 (16%)
Query: 91 CHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECE----VSGLCRHGGRCVNTHG 146
C P GF C C +GYR C DI+EC+ S LC + RC+NT G
Sbjct: 1481 CVRVPEGFTCRCFDGYRLDMTRMA--------CVDINECDEAEAASPLCVNA-RCLNTDG 1531
Query: 147 SFECYCMDGYLPRNGPEPFHP 167
SF C C G+ P + P P
Sbjct: 1532 SFRCICRPGFAPTHQPHHCAP 1552
Score = 52.8 bits (125), Expect = 1e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 9/80 (11%)
Query: 73 DKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS 132
D +ECQ VC + C NT G+ C C GY + C D DEC
Sbjct: 1186 DVDECQLFRDQVCKSGV-CVNTAPGYSCYCSNGY--------YYHTQRLECIDNDECADE 1236
Query: 133 GLCRHGGRCVNTHGSFECYC 152
GGRCVNT GS+ C C
Sbjct: 1237 EPACEGGRCVNTVGSYHCTC 1256
Score = 48.5 bits (114), Expect = 2e-05
Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 123 CTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYL 157
C D+DEC G C+HG C NT G + C C DG+L
Sbjct: 288 CEDVDECATGGRCQHG-ECANTRGGYTCVCPDGFL 321
Score = 38.9 bits (89), Expect = 0.018
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 6/83 (7%)
Query: 35 GLDVCATCHEHATCQQREGKKICICNYGFVG-NGRTQCVDKNECQFGATLVCGNHTSCHN 93
G+ C C E +R C GF NG C D +EC G H C N
Sbjct: 253 GVHDCQLCSERLGNSERVSAPDGPCPTGFERVNG--SCEDVDECATGGRC---QHGECAN 307
Query: 94 TPGGFYCICLEGYRATNNNKTFI 116
T GG+ C+C +G+ ++ + I
Sbjct: 308 TRGGYTCVCPDGFLLDSSRSSCI 330
Score = 35.8 bits (81), Expect = 0.15
Identities = 15/34 (44%), Positives = 22/34 (64%), Gaps = 3/34 (8%)
Query: 125 DIDECEV--SGLCRHGGRCVNTHGSFECYCMDGY 156
D+DEC++ +C+ G CVNT + CYC +GY
Sbjct: 1186 DVDECQLFRDQVCK-SGVCVNTAPGYSCYCSNGY 1218
Score = 31.2 bits (69), Expect = 3.7
Identities = 23/88 (26%), Positives = 32/88 (36%), Gaps = 14/88 (15%)
Query: 125 DIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDAT--SCTEIDCGTP 182
+ +EC + C +G RCV F C C DGY D T +C +I+
Sbjct: 1466 EAEECGILDGCTNG-RCVRVPEGFTCRCFDGY-----------RLDMTRMACVDINECDE 1513
Query: 183 PEVPDGYIIGNYTSSLGSQVRYACREGF 210
E + + R CR GF
Sbjct: 1514 AEAASPLCVNARCLNTDGSFRCICRPGF 1541
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 85.5 bits (210), Expect = 2e-16
Identities = 56/149 (37%), Positives = 66/149 (44%), Gaps = 26/149 (17%)
Query: 36 LDVCAT----CHEHATCQQREGKKICICNYGF-VGNGRT-QCVDKNECQFGATLVCGNHT 89
+D C++ C H C EG C C G+ +GR C D NEC G C H
Sbjct: 798 VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD--FCFPHG 855
Query: 90 SCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFE 149
C NT G F C C GYR G C D+DEC LC+ G C NT GSFE
Sbjct: 856 ECLNTDGSFACTCAPGYRPGPR--------GASCLDVDECSEEDLCQ-SGICTNTDGSFE 906
Query: 150 CYCMDGYLPRNGPEPFHPTTDATSCTEID 178
C C G+ R GP D SC ++D
Sbjct: 907 CICPPGH--RAGP-------DLASCLDVD 926
Score = 79.0 bits (193), Expect = 2e-14
Identities = 61/201 (30%), Positives = 72/201 (35%), Gaps = 62/201 (30%)
Query: 22 GLARGAAGAPGPDGLDVCATCHEHAT---CQQREGKKICICNYGFVGNG----------- 67
G GAP D +D CA T C+ EG C+C GF N
Sbjct: 703 GFRSRGPGAPCQD-VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC 761
Query: 68 ------------------------------RTQCVDKNECQFGATLVCGNHTSCHNTPGG 97
R +C D +EC GA CG H C NT G
Sbjct: 762 ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAP-PCGPHGHCTNTEGS 820
Query: 98 FYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYL 157
F C C GYRA + P C D++EC C G C+NT GSF C C GY
Sbjct: 821 FRCSCAPGYRAPSGR----PGP---CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYR 873
Query: 158 PRNGPEPFHPTTDATSCTEID 178
P GP SC ++D
Sbjct: 874 P--GPR-------GASCLDVD 885
Score = 75.1 bits (183), Expect = 2e-13
Identities = 52/163 (31%), Positives = 66/163 (40%), Gaps = 28/163 (17%)
Query: 32 GPDGL-DVCATCHEHAT-------CQQREGKKICI--CNYGFVGNGRTQCVDKNECQFGA 81
GP+G D C E+ C+ G C C+ G+ C D +EC+ +
Sbjct: 961 GPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRS 1020
Query: 82 TLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECE-VSGLCRHGGR 140
CG H C N PG F C+C +GY DG C D++ECE + G+C
Sbjct: 1021 --FCGAHAVCQNLPGSFQCLCDQGYEGAR--------DGRHCVDVNECETLQGVCG-AAL 1069
Query: 141 CVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPP 183
C N GSF C C N PE F P T GT P
Sbjct: 1070 CENVEGSFLCVC------PNSPEEFDPMTGRCVPPRTSAGTFP 1106
Score = 71.2 bits (173), Expect = 3e-12
Identities = 42/111 (37%), Positives = 53/111 (47%), Gaps = 13/111 (11%)
Query: 48 CQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C+ G C+C GF G +C+D +EC C + C NTPG F C+C GY
Sbjct: 566 CENSPGSFRCVCGPGFRAGPRAAECLDVDECH-RVPPPC-DLGRCENTPGSFLCVCPAGY 623
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRCVNTHGSFECYCMDGY 156
+A + G C D+DEC S GLC G C N GSF C C G+
Sbjct: 624 QAAPH--------GASCQDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGF 665
Score = 69.7 bits (169), Expect = 9e-12
Identities = 69/224 (30%), Positives = 88/224 (39%), Gaps = 38/224 (16%)
Query: 28 AGAPGPDGLDVCATCH------EHATCQQREGKKICICNYGFVGNGR-TQCVDKNECQFG 80
AG + LDV CH + C+ G +C+C G+ C D +EC
Sbjct: 583 AGPRAAECLDV-DECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQS 641
Query: 81 ATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFC-TDIDECEVSGLCRHGG 139
L CG +C N PG F C+C G+R G+ C D+DEC G
Sbjct: 642 PGL-CGRG-ACKNLPGSFRCVCPAGFR------------GSACEEDVDECAQEPPPCGPG 687
Query: 140 RCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLG 199
RC NT GSF C C G+ R P P D C +PP P Y G ++ G
Sbjct: 688 RCDNTAGSFHCACPAGFRSRG---PGAPCQDVDECAR----SPP--PCTY--GRCENTEG 736
Query: 200 SQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPP 243
S + C GF P S C + E+ L C C N P
Sbjct: 737 S-FQCVCPMGF--QPNTAGSECEDVDECEN-HLACPGQECVNSP 776
Score = 67.4 bits (163), Expect = 5e-11
Identities = 43/139 (30%), Positives = 54/139 (38%), Gaps = 19/139 (13%)
Query: 48 CQQREGKKICI--CNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI--CL 103
C+ G C+ C+ G+ C D +ECQ +CG C NTPG + C C
Sbjct: 941 CENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR-CENTPGSYRCTPACD 999
Query: 104 EGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPE 163
GY+ P G C D+DEC C C N GSF+C C GY G
Sbjct: 1000 PGYQ---------PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGY---EGAR 1047
Query: 164 PFHPTTDATSCTEID--CG 180
D C + CG
Sbjct: 1048 DGRHCVDVNECETLQGVCG 1066
Score = 66.6 bits (161), Expect = 8e-11
Identities = 53/146 (36%), Positives = 67/146 (45%), Gaps = 27/146 (18%)
Query: 31 PGPDG---LDVCATCHEHATCQQ-----REGKKICICNYGF-VGNGRTQCVDKNECQFGA 81
PGP G LDV C E CQ +G CIC G G C+D +EC+
Sbjct: 874 PGPRGASCLDV-DECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERG 932
Query: 82 TLVCGNHTSCHNTPGGFYCI--CLEGYRATNNNKTFIPNDGTFCTDIDECEVSG--LCRH 137
+CG+ C N+PG + C+ C GY A +GT C D+DEC+ G +C
Sbjct: 933 PALCGSQ-RCENSPGSYRCVRDCDPGYHA--------GPEGT-CDDVDECQEYGPEIC-G 981
Query: 138 GGRCVNTHGSFEC--YCMDGYLPRNG 161
RC NT GS+ C C GY P G
Sbjct: 982 AQRCENTPGSYRCTPACDPGYQPTPG 1007
Score = 66.2 bits (160), Expect = 1e-10
Identities = 60/195 (30%), Positives = 80/195 (41%), Gaps = 39/195 (20%)
Query: 26 GAAGAPGPDGLDVCAT----CHEHATCQQREGKKICICNYGFVGNGR-TQCVDKNECQFG 80
G G+ + +D CA C C G C C GF G C D +EC
Sbjct: 664 GFRGSACEEDVDECAQEPPPCGP-GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARS 722
Query: 81 ATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPND-GTFCTDIDECEVSGLCRHGG 139
+ C NT G F C+C G++ PN G+ C D+DECE C G
Sbjct: 723 PPPC--TYGRCENTEGSFQCVCPMGFQ---------PNTAGSECEDVDECENHLACP-GQ 770
Query: 140 RCVNTHGSFEC-YCMDGYLPRNGPEPFHPTTDATSCTEID---CGTPPEVPDGYIIGNYT 195
CVN+ GSF+C C G+ G CT++D G PP P G+ T
Sbjct: 771 ECVNSPGSFQCRTCPSGHHLHRG-----------RCTDVDECSSGAPPCGPHGHC----T 815
Query: 196 SSLGSQVRYACREGF 210
++ GS R +C G+
Sbjct: 816 NTEGS-FRCSCAPGY 829
Score = 56.2 bits (134), Expect = 1e-07
Identities = 58/192 (30%), Positives = 74/192 (38%), Gaps = 49/192 (25%)
Query: 84 VCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVN 143
VCG C + P G+ C C G+R + GT C D+DEC GRC N
Sbjct: 518 VCGPGR-CISRPSGYTCACDSGFR--------LSPQGTRCIDVDECRRVPPPCAPGRCEN 568
Query: 144 THGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQV 202
+ GSF C C G+ R GP A C ++D C P D +G ++ GS +
Sbjct: 569 SPGSFRCVCGPGF--RAGPR-------AAECLDVDECHRVPPPCD---LGRCENTPGSFL 616
Query: 203 RYACREGFFSVPE----DTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRL 258
C G+ + P V CT +SP L C C N P
Sbjct: 617 -CVCPAGYQAAPHGASCQDVDECT-----QSPGL-CGRGACKNLP--------------- 654
Query: 259 GGVARYVCQEGF 270
G R VC GF
Sbjct: 655 -GSFRCVCPAGF 665
Score = 55.1 bits (131), Expect = 2e-07
Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 13/81 (16%)
Query: 91 CHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECE----VSGLCRHGGRCVNTHG 146
C P GF C C +GYR C DI+EC+ S LC + RC+NT G
Sbjct: 1511 CVRVPEGFTCRCFDGYRLDMTRMA--------CVDINECDEAEAASPLCVNA-RCLNTDG 1561
Query: 147 SFECYCMDGYLPRNGPEPFHP 167
SF C C G+ P + P P
Sbjct: 1562 SFRCICRPGFAPTHQPHHCAP 1582
Score = 52.8 bits (125), Expect = 1e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 9/80 (11%)
Query: 73 DKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS 132
D +ECQ VC + C NT G+ C C GY + C D DEC
Sbjct: 1216 DVDECQLFRDQVCKSGV-CVNTAPGYSCYCSNGY--------YYHTQRLECIDNDECADE 1266
Query: 133 GLCRHGGRCVNTHGSFECYC 152
GGRCVNT GS+ C C
Sbjct: 1267 EPACEGGRCVNTVGSYHCTC 1286
Score = 48.5 bits (114), Expect = 2e-05
Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 123 CTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYL 157
C D+DEC G C+HG C NT G + C C DG+L
Sbjct: 318 CEDVDECATGGRCQHG-ECANTRGGYTCVCPDGFL 351
Score = 38.9 bits (89), Expect = 0.018
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 6/83 (7%)
Query: 35 GLDVCATCHEHATCQQREGKKICICNYGFVG-NGRTQCVDKNECQFGATLVCGNHTSCHN 93
G+ C C E +R C GF NG C D +EC G H C N
Sbjct: 283 GVHDCQLCSERLGNSERVSAPDGPCPTGFERVNG--SCEDVDECATGGRC---QHGECAN 337
Query: 94 TPGGFYCICLEGYRATNNNKTFI 116
T GG+ C+C +G+ ++ + I
Sbjct: 338 TRGGYTCVCPDGFLLDSSRSSCI 360
Score = 35.8 bits (81), Expect = 0.15
Identities = 15/34 (44%), Positives = 22/34 (64%), Gaps = 3/34 (8%)
Query: 125 DIDECEV--SGLCRHGGRCVNTHGSFECYCMDGY 156
D+DEC++ +C+ G CVNT + CYC +GY
Sbjct: 1216 DVDECQLFRDQVCK-SGVCVNTAPGYSCYCSNGY 1248
Score = 31.2 bits (69), Expect = 3.7
Identities = 23/88 (26%), Positives = 32/88 (36%), Gaps = 14/88 (15%)
Query: 125 DIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDAT--SCTEIDCGTP 182
+ +EC + C +G RCV F C C DGY D T +C +I+
Sbjct: 1496 EAEECGILDGCTNG-RCVRVPEGFTCRCFDGY-----------RLDMTRMACVDINECDE 1543
Query: 183 PEVPDGYIIGNYTSSLGSQVRYACREGF 210
E + + R CR GF
Sbjct: 1544 AEAASPLCVNARCLNTDGSFRCICRPGF 1571
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 85.5 bits (210), Expect = 2e-16
Identities = 56/149 (37%), Positives = 66/149 (44%), Gaps = 26/149 (17%)
Query: 36 LDVCAT----CHEHATCQQREGKKICICNYGF-VGNGRT-QCVDKNECQFGATLVCGNHT 89
+D C++ C H C EG C C G+ +GR C D NEC G C H
Sbjct: 835 VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD--FCFPHG 892
Query: 90 SCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFE 149
C NT G F C C GYR G C D+DEC LC+ G C NT GSFE
Sbjct: 893 ECLNTDGSFACTCAPGYRPGPR--------GASCLDVDECSEEDLCQ-SGICTNTDGSFE 943
Query: 150 CYCMDGYLPRNGPEPFHPTTDATSCTEID 178
C C G+ R GP D SC ++D
Sbjct: 944 CICPPGH--RAGP-------DLASCLDVD 963
Score = 79.0 bits (193), Expect = 2e-14
Identities = 61/201 (30%), Positives = 72/201 (35%), Gaps = 62/201 (30%)
Query: 22 GLARGAAGAPGPDGLDVCATCHEHAT---CQQREGKKICICNYGFVGNG----------- 67
G GAP D +D CA T C+ EG C+C GF N
Sbjct: 740 GFRSRGPGAPCQD-VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC 798
Query: 68 ------------------------------RTQCVDKNECQFGATLVCGNHTSCHNTPGG 97
R +C D +EC GA CG H C NT G
Sbjct: 799 ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAP-PCGPHGHCTNTEGS 857
Query: 98 FYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYL 157
F C C GYRA + P C D++EC C G C+NT GSF C C GY
Sbjct: 858 FRCSCAPGYRAPSGR----PGP---CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYR 910
Query: 158 PRNGPEPFHPTTDATSCTEID 178
P GP SC ++D
Sbjct: 911 P--GPR-------GASCLDVD 922
Score = 75.1 bits (183), Expect = 2e-13
Identities = 52/163 (31%), Positives = 66/163 (40%), Gaps = 28/163 (17%)
Query: 32 GPDGL-DVCATCHEHAT-------CQQREGKKICI--CNYGFVGNGRTQCVDKNECQFGA 81
GP+G D C E+ C+ G C C+ G+ C D +EC+ +
Sbjct: 998 GPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRS 1057
Query: 82 TLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECE-VSGLCRHGGR 140
CG H C N PG F C+C +GY DG C D++ECE + G+C
Sbjct: 1058 --FCGAHAVCQNLPGSFQCLCDQGYEGAR--------DGRHCVDVNECETLQGVCG-AAL 1106
Query: 141 CVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPP 183
C N GSF C C N PE F P T GT P
Sbjct: 1107 CENVEGSFLCVC------PNSPEEFDPMTGRCVPPRTSAGTFP 1143
Score = 71.2 bits (173), Expect = 3e-12
Identities = 42/111 (37%), Positives = 53/111 (47%), Gaps = 13/111 (11%)
Query: 48 CQQREGKKICICNYGF-VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C+ G C+C GF G +C+D +EC C + C NTPG F C+C GY
Sbjct: 603 CENSPGSFRCVCGPGFRAGPRAAECLDVDECH-RVPPPC-DLGRCENTPGSFLCVCPAGY 660
Query: 107 RATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRCVNTHGSFECYCMDGY 156
+A + G C D+DEC S GLC G C N GSF C C G+
Sbjct: 661 QAAPH--------GASCQDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGF 702
Score = 69.7 bits (169), Expect = 9e-12
Identities = 69/224 (30%), Positives = 88/224 (39%), Gaps = 38/224 (16%)
Query: 28 AGAPGPDGLDVCATCH------EHATCQQREGKKICICNYGFVGNGR-TQCVDKNECQFG 80
AG + LDV CH + C+ G +C+C G+ C D +EC
Sbjct: 620 AGPRAAECLDV-DECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQS 678
Query: 81 ATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFC-TDIDECEVSGLCRHGG 139
L CG +C N PG F C+C G+R G+ C D+DEC G
Sbjct: 679 PGL-CGRG-ACKNLPGSFRCVCPAGFR------------GSACEEDVDECAQEPPPCGPG 724
Query: 140 RCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLG 199
RC NT GSF C C G+ R P P D C +PP P Y G ++ G
Sbjct: 725 RCDNTAGSFHCACPAGFRSRG---PGAPCQDVDECAR----SPP--PCTY--GRCENTEG 773
Query: 200 SQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPP 243
S + C GF P S C + E+ L C C N P
Sbjct: 774 S-FQCVCPMGF--QPNTAGSECEDVDECEN-HLACPGQECVNSP 813
Score = 67.4 bits (163), Expect = 5e-11
Identities = 43/139 (30%), Positives = 54/139 (38%), Gaps = 19/139 (13%)
Query: 48 CQQREGKKICI--CNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI--CL 103
C+ G C+ C+ G+ C D +ECQ +CG C NTPG + C C
Sbjct: 978 CENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR-CENTPGSYRCTPACD 1036
Query: 104 EGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPE 163
GY+ P G C D+DEC C C N GSF+C C GY G
Sbjct: 1037 PGYQ---------PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGY---EGAR 1084
Query: 164 PFHPTTDATSCTEID--CG 180
D C + CG
Sbjct: 1085 DGRHCVDVNECETLQGVCG 1103
Score = 66.6 bits (161), Expect = 8e-11
Identities = 53/146 (36%), Positives = 67/146 (45%), Gaps = 27/146 (18%)
Query: 31 PGPDG---LDVCATCHEHATCQQ-----REGKKICICNYGF-VGNGRTQCVDKNECQFGA 81
PGP G LDV C E CQ +G CIC G G C+D +EC+
Sbjct: 911 PGPRGASCLDV-DECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERG 969
Query: 82 TLVCGNHTSCHNTPGGFYCI--CLEGYRATNNNKTFIPNDGTFCTDIDECEVSG--LCRH 137
+CG+ C N+PG + C+ C GY A +GT C D+DEC+ G +C
Sbjct: 970 PALCGSQ-RCENSPGSYRCVRDCDPGYHA--------GPEGT-CDDVDECQEYGPEIC-G 1018
Query: 138 GGRCVNTHGSFEC--YCMDGYLPRNG 161
RC NT GS+ C C GY P G
Sbjct: 1019 AQRCENTPGSYRCTPACDPGYQPTPG 1044
Score = 66.2 bits (160), Expect = 1e-10
Identities = 60/195 (30%), Positives = 80/195 (41%), Gaps = 39/195 (20%)
Query: 26 GAAGAPGPDGLDVCAT----CHEHATCQQREGKKICICNYGFVGNGR-TQCVDKNECQFG 80
G G+ + +D CA C C G C C GF G C D +EC
Sbjct: 701 GFRGSACEEDVDECAQEPPPCGP-GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARS 759
Query: 81 ATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPND-GTFCTDIDECEVSGLCRHGG 139
+ C NT G F C+C G++ PN G+ C D+DECE C G
Sbjct: 760 PPPC--TYGRCENTEGSFQCVCPMGFQ---------PNTAGSECEDVDECENHLACP-GQ 807
Query: 140 RCVNTHGSFEC-YCMDGYLPRNGPEPFHPTTDATSCTEID---CGTPPEVPDGYIIGNYT 195
CVN+ GSF+C C G+ G CT++D G PP P G+ T
Sbjct: 808 ECVNSPGSFQCRTCPSGHHLHRG-----------RCTDVDECSSGAPPCGPHGHC----T 852
Query: 196 SSLGSQVRYACREGF 210
++ GS R +C G+
Sbjct: 853 NTEGS-FRCSCAPGY 866
Score = 56.2 bits (134), Expect = 1e-07
Identities = 58/192 (30%), Positives = 74/192 (38%), Gaps = 49/192 (25%)
Query: 84 VCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVN 143
VCG C + P G+ C C G+R + GT C D+DEC GRC N
Sbjct: 555 VCGPGR-CISRPSGYTCACDSGFR--------LSPQGTRCIDVDECRRVPPPCAPGRCEN 605
Query: 144 THGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQV 202
+ GSF C C G+ R GP A C ++D C P D +G ++ GS +
Sbjct: 606 SPGSFRCVCGPGF--RAGPR-------AAECLDVDECHRVPPPCD---LGRCENTPGSFL 653
Query: 203 RYACREGFFSVPE----DTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRL 258
C G+ + P V CT +SP L C C N P
Sbjct: 654 -CVCPAGYQAAPHGASCQDVDECT-----QSPGL-CGRGACKNLP--------------- 691
Query: 259 GGVARYVCQEGF 270
G R VC GF
Sbjct: 692 -GSFRCVCPAGF 702
Score = 55.1 bits (131), Expect = 2e-07
Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 13/81 (16%)
Query: 91 CHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECE----VSGLCRHGGRCVNTHG 146
C P GF C C +GYR C DI+EC+ S LC + RC+NT G
Sbjct: 1548 CVRVPEGFTCRCFDGYRLDMTRMA--------CVDINECDEAEAASPLCVNA-RCLNTDG 1598
Query: 147 SFECYCMDGYLPRNGPEPFHP 167
SF C C G+ P + P P
Sbjct: 1599 SFRCICRPGFAPTHQPHHCAP 1619
Score = 52.8 bits (125), Expect = 1e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 9/80 (11%)
Query: 73 DKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS 132
D +ECQ VC + C NT G+ C C GY + C D DEC
Sbjct: 1253 DVDECQLFRDQVCKSGV-CVNTAPGYSCYCSNGY--------YYHTQRLECIDNDECADE 1303
Query: 133 GLCRHGGRCVNTHGSFECYC 152
GGRCVNT GS+ C C
Sbjct: 1304 EPACEGGRCVNTVGSYHCTC 1323
Score = 48.5 bits (114), Expect = 2e-05
Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 123 CTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYL 157
C D+DEC G C+HG C NT G + C C DG+L
Sbjct: 355 CEDVDECATGGRCQHG-ECANTRGGYTCVCPDGFL 388
Score = 38.9 bits (89), Expect = 0.018
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 6/83 (7%)
Query: 35 GLDVCATCHEHATCQQREGKKICICNYGFVG-NGRTQCVDKNECQFGATLVCGNHTSCHN 93
G+ C C E +R C GF NG C D +EC G H C N
Sbjct: 320 GVHDCQLCSERLGNSERVSAPDGPCPTGFERVNG--SCEDVDECATGGRC---QHGECAN 374
Query: 94 TPGGFYCICLEGYRATNNNKTFI 116
T GG+ C+C +G+ ++ + I
Sbjct: 375 TRGGYTCVCPDGFLLDSSRSSCI 397
Score = 35.8 bits (81), Expect = 0.15
Identities = 15/34 (44%), Positives = 22/34 (64%), Gaps = 3/34 (8%)
Query: 125 DIDECEV--SGLCRHGGRCVNTHGSFECYCMDGY 156
D+DEC++ +C+ G CVNT + CYC +GY
Sbjct: 1253 DVDECQLFRDQVCK-SGVCVNTAPGYSCYCSNGY 1285
Score = 31.2 bits (69), Expect = 3.7
Identities = 23/88 (26%), Positives = 32/88 (36%), Gaps = 14/88 (15%)
Query: 125 DIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDAT--SCTEIDCGTP 182
+ +EC + C +G RCV F C C DGY D T +C +I+
Sbjct: 1533 EAEECGILDGCTNG-RCVRVPEGFTCRCFDGY-----------RLDMTRMACVDINECDE 1580
Query: 183 PEVPDGYIIGNYTSSLGSQVRYACREGF 210
E + + R CR GF
Sbjct: 1581 AEAASPLCVNARCLNTDGSFRCICRPGF 1608
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 85.5 bits (210), Expect = 2e-16
Identities = 78/298 (26%), Positives = 119/298 (39%), Gaps = 38/298 (12%)
Query: 26 GAAGAPGPDGLDV--CAT---CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFG 80
G+ P LDV CA C EHA+C +G IC C + G+G+ C + +C+
Sbjct: 1734 GSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKN-CAEPIKCK-- 1790
Query: 81 ATLVCGNHTSCHNTPGGFYCI-------CLEGYRATNNNKTFIPNDGTFCTDIDECEVSG 133
GN + H++ G Y + C EGY+ K G + I C+
Sbjct: 1791 ---APGNPENGHSS-GEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVS 1846
Query: 134 LCRHG---GRCVN----THGSFECY-CMDGYLPRNGPEPFHPTTDATS-----CTEIDCG 180
+ C+ T GS Y C GY E + S C + C
Sbjct: 1847 CGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCS 1906
Query: 181 TPPEVPDG-YIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINC 239
+P + +G YI+ T S Y+C G+ S+ ++ CT G W+ C + C
Sbjct: 1907 SPENINNGKYILSGLTYL--STASYSCDTGY-SLQGPSIIECTASGIWDRAPPACHLVFC 1963
Query: 240 GNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTWRESTLTCTEI 297
G PP ++ A++ GN+ + Y C+EG+ + G T C G W S C +
Sbjct: 1964 GEPPAIKDAVITGNNFT-FRNTVTYTCKEGY-TLAGLDTIECLADGKWSRSDQQCLAV 2019
Score = 84.0 bits (206), Expect = 5e-16
Identities = 71/273 (26%), Positives = 114/273 (41%), Gaps = 44/273 (16%)
Query: 51 REGKKICI-CNYGF--VGNGRTQCVDKNECQFGATLVCGNHTSCHNTP---GGFYCI--- 101
+ G K+ + C+ GF VGN C+ N+ Q+ L SC P GF+
Sbjct: 1649 KPGSKVNLFCDPGFQLVGNPVQYCL--NQGQWTQPLPHCERISCGVPPPLENGFHSADDF 1706
Query: 102 ---------CLEGYRATNNNKTFIPNDGTF------CTDIDECEVSGLCRHGGRCVNTHG 146
C GY +++ F ++G++ C D+DEC V C C+N G
Sbjct: 1707 YAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDG 1766
Query: 147 SFECYCMDGYLPRNGPEPFHPTTDATSCTE-IDCGTPPEVPDGYIIGN-YTSSLGSQVRY 204
S+ C C+ Y T D +C E I C P +G+ G YT +G++V +
Sbjct: 1767 SYICSCVPPY-----------TGDGKNCAEPIKCKAPGNPENGHSSGEIYT--VGAEVTF 1813
Query: 205 ACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVARY 264
+C+EG + + T +C G W +C+ ++CG P + + + G Y
Sbjct: 1814 SCQEG-YQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENG-CIEELAFTFGSKVTY 1871
Query: 265 VCQEGFESPGGKITSVCTEKGTWRESTLTCTEI 297
C +G+ G K +S C +W S C +
Sbjct: 1872 RCNKGYTLAGDKESS-CLANSSWSHSPPVCEPV 1903
Score = 82.8 bits (203), Expect = 1e-15
Identities = 50/161 (31%), Positives = 74/161 (45%), Gaps = 15/161 (9%)
Query: 139 GRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIG-NYTSS 197
G +NT EC R G ++P+ + C + CG PP + +GY G NY S
Sbjct: 2115 GFVLNTSAKIECM-------RGGQ--WNPSPMSIQCIPVRCGEPPSIMNGYASGSNY--S 2163
Query: 198 LGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSR 257
G+ V Y+C +GF+ + + S+C G W SP C ++CG PP++ + L
Sbjct: 2164 FGAMVAYSCNKGFY-IKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRI 2222
Query: 258 LGGVARYVCQEGFESPGGKITSVCTEKGTWR-ESTLTCTEI 297
RY C G++S G + VC W ES L C +
Sbjct: 2223 FESEVRYQCNPGYKSVGSPV-FVCQANRHWHSESPLMCVPL 2262
Score = 66.6 bits (161), Expect = 8e-11
Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Query: 174 CTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLH 233
C + C PP + G I + GS V+Y+C GFF + ++ + C GTW SP
Sbjct: 2376 CKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFF-LRGNSTTLCQPDGTWSSPLPE 2434
Query: 234 CQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTWRESTLT 293
C + C P E+ + I+ + L A Y C+ GFE G T++C E G W T
Sbjct: 2435 CVPVECPQPEEIPNGIIDVQGLAYL-STALYTCKPGFELV-GNTTTLCGENGHWLGGKPT 2492
Query: 294 CTEI 297
C I
Sbjct: 2493 CKAI 2496
Score = 64.7 bits (156), Expect = 3e-10
Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Query: 173 SCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPK- 231
+C + CG PP+V +G++ S+VRY C G+ SV V C W S
Sbjct: 2198 TCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSP-VFVCQANRHWHSESP 2256
Query: 232 LHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTWREST 291
L C ++CG PP +++ + G + +G ++ C EG+E G + C + G W + +
Sbjct: 2257 LMCVPLDCGKPPPIQNGFMKG-ENFEVGSKVQFFCNEGYELVGDS-SWTCQKSGKWNKKS 2314
Score = 63.2 bits (152), Expect = 9e-10
Identities = 42/142 (29%), Positives = 60/142 (42%), Gaps = 10/142 (7%)
Query: 152 CMDGYLPRNGPEPFHPTTDAT------SCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYA 205
C GY GP H T + T C C P +P+ ++ + V
Sbjct: 3325 CNRGY-SLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIK 3383
Query: 206 CREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVARYV 265
CREGF + + +C TW C++I+CG P + +AI G H + G + Y
Sbjct: 3384 CREGFL-LQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVH-YQYGDMITYS 3441
Query: 266 CQEGFESPGGKITSVCTEKGTW 287
C G+ G + SVC E GTW
Sbjct: 3442 CYSGYMLE-GFLRSVCLENGTW 3462
Score = 62.8 bits (151), Expect = 1e-09
Identities = 60/268 (22%), Positives = 105/268 (39%), Gaps = 38/268 (14%)
Query: 59 CNYGFVGNGRTQCVDKNECQFGATLVCGNHTSC-------HNTPGGFYCI--------CL 103
C+ G++ +G + +++ + A + +C H P GF I C
Sbjct: 2917 CHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCF 2976
Query: 104 EGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVN---THGS-FEC------YCM 153
GY+ N+ ++G++ C CR + +G+ F+C C
Sbjct: 2977 PGYKLHGNSSRRCLSNGSWSGSSPSCLP---CRCSTPVIEYGTVNGTDFDCGKAARIQCF 3033
Query: 154 DGYLPRNGPEPFHPTTDATS-----CTEIDCGTPPEVPDGYIIGNYTSSLGSQV-RYACR 207
G+ E S C CG+ P +P+ +I + TSS V Y+CR
Sbjct: 3034 KGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFI--SETSSWKENVITYSCR 3091
Query: 208 EGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQ 267
G+ + + CT G W P C+ ++CG+PP + +A+ G + V + C
Sbjct: 3092 SGYV-IQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEV-KLRCL 3149
Query: 268 EGFESPGGKITSVCTEKGTWRESTLTCT 295
EG+ T C + G W ++C+
Sbjct: 3150 EGYTMDTDTDTFTCQKDGRWFPERISCS 3177
Score = 61.6 bits (148), Expect = 3e-09
Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 4/115 (3%)
Query: 173 SCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKL 232
+C + CG PP + D I GN + + V Y C+EG+ DT+ C G W
Sbjct: 1957 ACHLVFCGEPPAIKDAVITGN-NFTFRNTVTYTCKEGYTLAGLDTIE-CLADGKWSRSDQ 2014
Query: 233 HCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTW 287
C ++C PP + HA H G +A Y C +G+ S +C +G W
Sbjct: 2015 QCLAVSCDEPPIVDHASPETAH-RLFGDIAFYYCSDGY-SLADNSQLLCNAQGKW 2067
Score = 60.1 bits (144), Expect = 7e-09
Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 9/128 (7%)
Query: 174 CTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTW---ESP 230
C +DCG PP + +G++ G +GS+V++ C EG + + D+ +C G W +P
Sbjct: 2259 CVPLDCGKPPPIQNGFMKGE-NFEVGSKVQFFCNEG-YELVGDSSWTCQKSGKWNKKSNP 2316
Query: 231 KLHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTWRES 290
K C C PP + + +++ ++ + GV + C+EG G + C W +S
Sbjct: 2317 K--CMPAKCPEPPLLENQLVLKELTTEV-GVVTFSCKEGHVLQGPSVLK-CLPSQQWNDS 2372
Query: 291 TLTCTEIL 298
C +L
Sbjct: 2373 FPVCKIVL 2380
Score = 58.9 bits (141), Expect = 2e-08
Identities = 71/283 (25%), Positives = 101/283 (35%), Gaps = 43/283 (15%)
Query: 32 GPDGLDVCATCHEHATCQQREGKKICICNYGFVGNGR----TQCVD---KNECQFGATLV 84
G D D +C C G CIC G+ G G T C K E G
Sbjct: 284 GKDCCDRMGSCK----CGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISS 339
Query: 85 C-----GNHTSCHNTPGGFYCICLEGYRATNNNKTFI-------PNDGTFCTDIDECEVS 132
C NHTS + C+C EGYRA+ + P +G F + +
Sbjct: 340 CIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFN 399
Query: 133 GLCRHGGRC---VNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGY 189
C G RC + GS C+ L +G E + C C + G+
Sbjct: 400 AAC--GVRCHPGFDLVGSSIILCLPNGL-WSGSESY--------CRVRTCPHLRQPKHGH 448
Query: 190 IIGNYTSSL-GSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHA 248
I + L + AC EG+ D + +C G W+ P+ C E +C +
Sbjct: 449 ISCSTREMLYKTTCLVACDEGYRLEGSDKL-TCQGNSQWDGPEPRCVERHCSTFQMPKDV 507
Query: 249 IL----VGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTW 287
I+ G ++ G + C++GF G K CT G W
Sbjct: 508 IISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKW 550
Score = 58.5 bits (140), Expect = 2e-08
Identities = 54/213 (25%), Positives = 79/213 (37%), Gaps = 26/213 (12%)
Query: 102 CLEGYRATNNNKTFIPNDGTFCTDIDEC----------------EVSGLCRHGGRCVNTH 145
C+ G+ N+ T DGT+ + + EC +V GL
Sbjct: 2408 CVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCK 2467
Query: 146 GSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYTS-SLGSQVRY 204
FE + G E H +C I+C P E+ +G +YT G V Y
Sbjct: 2468 PGFE---LVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKF--SYTDLHYGQTVTY 2522
Query: 205 ACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVARY 264
+C G F + + +C G W+ C I+C +P + + + G S G + Y
Sbjct: 2523 SCNRG-FRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYS-YGAIIIY 2580
Query: 265 VCQEGFESPGGKITSVCTEKGTWRESTLTCTEI 297
C GF+ G C E G W S TC I
Sbjct: 2581 SCFPGFQ-VAGHAMQTCEESG-WSSSIPTCMPI 2611
Score = 57.8 bits (138), Expect = 4e-08
Identities = 41/140 (29%), Positives = 58/140 (41%), Gaps = 27/140 (19%)
Query: 42 CHEHATCQQREGKKICICNYGFVGNGRTQC-VDKNECQFGATLVCGNHTSCHNTPGGFYC 100
CH TCQQ +C+C G+ G +C D +EC + L C N+ C + G F C
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTG---LKCETDIDEC---SPLPCLNNGVCKDLVGEFIC 1255
Query: 101 ICLEGYRATNNNKTFIPNDGTFCTD-IDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPR 159
C GY G C + I+EC S C + G CV+ + C C+ G++
Sbjct: 1256 ECPSGY------------TGQRCEENINECS-SSPCLNKGICVDGVAGYRCTCVKGFV-- 1300
Query: 160 NGPEPFHPTTDATSCTEIDC 179
H T+ C C
Sbjct: 1301 ----GLHCETEVNECQSNPC 1316
Score = 56.6 bits (135), Expect = 8e-08
Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 8/123 (6%)
Query: 174 CTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFF--SVPEDTVSSCTGLGTWESPK 231
C + C TPP++ +G G +V + C EG+ P+ T C G W++
Sbjct: 2886 CVPVRCATPPQLANGVTEG-LDYGFMKEVTFHCHEGYILHGAPKLT---CQSDGNWDAEI 2941
Query: 232 LHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTWREST 291
C+ +NCG P ++ H G S GG +Y C G++ G + C G+W S+
Sbjct: 2942 PLCKPVNCGPPEDLAHGFPNG-FSFIHGGHIQYQCFPGYKLHGNS-SRRCLSNGSWSGSS 2999
Query: 292 LTC 294
+C
Sbjct: 3000 PSC 3002
Score = 55.1 bits (131), Expect = 2e-07
Identities = 39/134 (29%), Positives = 55/134 (41%), Gaps = 21/134 (15%)
Query: 26 GAAGAPGPDGLDVCAT--CHEHATCQQREGKKICICNYGFVGNGRTQC-VDKNECQFGAT 82
G G + ++ C++ C C C C GFVG C + NECQ
Sbjct: 1260 GYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVG---LHCETEVNECQSNP- 1315
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCV 142
C N+ C + GGF C C G+ T K ++DEC +S C++G C
Sbjct: 1316 --CLNNAVCEDQVGGFLCKCPPGFLGTRCGK-----------NVDEC-LSQPCKNGATCK 1361
Query: 143 NTHGSFECYCMDGY 156
+ SF C C G+
Sbjct: 1362 DGANSFRCLCAAGF 1375
Score = 55.1 bits (131), Expect = 2e-07
Identities = 39/155 (25%), Positives = 63/155 (40%), Gaps = 11/155 (7%)
Query: 148 FEC---YCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGN-YTSSLGSQVR 203
+EC Y ++G R + + D C +DC +PP +G + G+ YT ++
Sbjct: 2799 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQ--KEIE 2856
Query: 204 YACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVAR 263
Y C EGF + C G+W C + C PP++ + + G + V
Sbjct: 2857 YTCNEGFL-LEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVT- 2914
Query: 264 YVCQEGFESPGG-KITSVCTEKGTWRESTLTCTEI 297
+ C EG+ G K+T C G W C +
Sbjct: 2915 FHCHEGYILHGAPKLT--CQSDGNWDAEIPLCKPV 2947
Score = 53.9 bits (128), Expect = 5e-07
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 19/116 (16%)
Query: 42 CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI 101
C +A C+ + G +C C GF+G + VD EC + C N +C + F C+
Sbjct: 1316 CLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVD--EC---LSQPCKNGATCKDGANSFRCL 1370
Query: 102 CLEGYRATNNNKTFIPNDGTFCT-DIDECEVSGLCRHGGRCVNTHGSFECYCMDGY 156
C G+ G+ C +I+EC+ S CR+ CV+ S+ C C G+
Sbjct: 1371 CAAGFT------------GSHCELNINECQ-SNPCRNQATCVDELNSYSCKCQPGF 1413
Score = 53.9 bits (128), Expect = 5e-07
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 174 CTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLH 233
C + CG+PP V + G + S+V+ C EG+ + +C G W ++
Sbjct: 3117 CEPLSCGSPPSVANAVATGE-AHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERIS 3175
Query: 234 CQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTW 287
C C P + H ++ G+ S + C EG+ G I SVC GTW
Sbjct: 3176 CSPKKCPLPENITHILVHGDDFS-VNRQVSVSCAEGYTFEGVNI-SVCQLDGTW 3227
Score = 51.6 bits (122), Expect = 3e-06
Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 49/173 (28%)
Query: 170 DATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWES 229
DA SC I C +P + +G++ G S G+ + Y+C G F V + +C G W S
Sbjct: 2547 DAPSCNAIHCDSPQPIENGFVEG-ADYSYGAIIIYSCFPG-FQVAGHAMQTCEESG-WSS 2603
Query: 230 PKLHCQEINCGNPP---------------------EMRHAILVGNHSS-RLGGVAR---- 263
C I+CG PP +M V H LG VA+
Sbjct: 2604 SIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWEN 2663
Query: 264 -------------------YVCQEGFESPGGKITSVCTEKGTWRESTLTCTEI 297
Y C G+E G + +C E GTW S +C I
Sbjct: 2664 TKESPATHSSNFLYGTMVSYTCNPGYELLGNPVL-ICQEDGTWNGSAPSCISI 2715
Score = 50.8 bits (120), Expect = 4e-06
Identities = 53/212 (25%), Positives = 77/212 (36%), Gaps = 26/212 (12%)
Query: 102 CLEGYRATNNNKTFI-PNDGTFCTDIDECE---------VSGLCRHGGR-CVNTHGSFEC 150
CLEGY + TF DG + + C ++ + HG VN S C
Sbjct: 3148 CLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSC 3207
Query: 151 ---YCMDGY----LPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGN-YTSSLGSQV 202
Y +G +G + P SC+ + CG P G+++G+ YT S +
Sbjct: 3208 AEGYTFEGVNISVCQLDGT--WEPPFSDESCSPVSCGKPESPEHGFVVGSKYT--FESTI 3263
Query: 203 RYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVA 262
Y C G + + + C W C+E C P E + + G
Sbjct: 3264 IYQCEPG-YELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNG-KADIENRTTGPNV 3321
Query: 263 RYVCQEGFESPGGKITSVCTEKGTWRESTLTC 294
Y C G+ S G + CTE GTW C
Sbjct: 3322 VYSCNRGY-SLEGPSEAHCTENGTWSHPVPLC 3352
Score = 49.7 bits (117), Expect = 1e-05
Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 4/127 (3%)
Query: 171 ATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESP 230
A SC I+C P +G++ TS +GS V+Y+C+ G D + C W
Sbjct: 2709 APSCISIECDLPTAPENGFLRFTETS-MGSAVQYSCKPGHILAGSD-LRLCLENRKWSGA 2766
Query: 231 KLHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTWRES 290
C+ I+C P + + + G++ + L Y C G+ G + C + W E
Sbjct: 2767 SPRCEAISCKKPNPVMNGSIKGSNYTYL-STLYYECDPGYVLNGTE-RRTCQDDKNWDED 2824
Query: 291 TLTCTEI 297
C +
Sbjct: 2825 EPICIPV 2831
Score = 49.3 bits (116), Expect = 1e-05
Identities = 29/124 (23%), Positives = 51/124 (41%), Gaps = 3/124 (2%)
Query: 174 CTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLH 233
C C PP + + ++ T+ +G V ++C+EG + +V C W
Sbjct: 2318 CMPAKCPEPPLLENQLVLKELTTEVGV-VTFSCKEGHV-LQGPSVLKCLPSQQWNDSFPV 2375
Query: 234 CQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTWRESTLT 293
C+ + C PP + + + + + G +Y C GF G T++C GTW
Sbjct: 2376 CKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNS-TTLCQPDGTWSSPLPE 2434
Query: 294 CTEI 297
C +
Sbjct: 2435 CVPV 2438
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/102 (26%), Positives = 40/102 (39%), Gaps = 3/102 (2%)
Query: 199 GSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRL 258
G+ V Y C G+ + + V C GTW C I C P + L +S +
Sbjct: 2678 GTMVSYTCNPGY-ELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETS-M 2735
Query: 259 GGVARYVCQEGFESPGGKITSVCTEKGTWRESTLTCTEILTK 300
G +Y C+ G G + +C E W ++ C I K
Sbjct: 2736 GSAVQYSCKPGHILAGSDL-RLCLENRKWSGASPRCEAISCK 2776
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 84.7 bits (208), Expect = 3e-16
Identities = 54/165 (32%), Positives = 76/165 (46%), Gaps = 18/165 (10%)
Query: 22 GLARGAAGAPGPDGLDVCAT----CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNEC 77
G G +G PG +D C+ CH A CQ C+C G+ G G+ QC D +EC
Sbjct: 20 GRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGK-QCEDIDEC 78
Query: 78 QFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLCR 136
+ G C N PG + C C +G+ + +DG C D+DEC + +G C+
Sbjct: 79 E-NDYYNGGCVHECINIPGNYRCTCFDGF--------MLAHDGHNCLDVDECQDNNGGCQ 129
Query: 137 HGGRCVNTHGSFECYCMDG-YLPRNGPEPFHPTTDATSCTEIDCG 180
CVN GS+EC C G +L N H + + +C D G
Sbjct: 130 Q--ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHG 172
Score = 67.0 bits (162), Expect = 6e-11
Identities = 41/113 (36%), Positives = 52/113 (46%), Gaps = 16/113 (14%)
Query: 47 TCQQREGKKICICNYGFV--GNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLE 104
TC+ C C GF +G+T C D NEC G C NT G F C C +
Sbjct: 255 TCKDTATGVRCSCPVGFTLQPDGKT-CKDINECLVNNG---GCDHFCRNTVGSFECGCRK 310
Query: 105 GYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYL 157
GY+ + +T C DIDEC C H C+N+ GSF+C C GY+
Sbjct: 311 GYKLLTDERT--------CQDIDECSFERTCDH--ICINSPGSFQCLCHRGYI 353
Score = 66.2 bits (160), Expect = 1e-10
Identities = 44/111 (39%), Positives = 55/111 (49%), Gaps = 19/111 (17%)
Query: 48 CQQREGKKICICNYGF--VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEG 105
C+ G C C G+ + + RT C D +EC F T +H C N+PG F C+C G
Sbjct: 297 CRNTVGSFECGCRKGYKLLTDERT-CQDIDECSFERTC---DHI-CINSPGSFQCLCHRG 351
Query: 106 YRATNNNKTFIPNDGTFCTDIDECEVS-GLCRHGGRCVNTHGSFECYCMDG 155
Y I T C D+DEC +S G C G CVNT GS+EC C G
Sbjct: 352 Y---------ILYGTTHCGDVDECSMSNGSCDQG--CVNTKGSYECVCPPG 391
Score = 41.6 bits (96), Expect = 0.003
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 36 LDVCA---TCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCH 92
+D C+ TC C G C+C+ G++ G T C D +EC + C C
Sbjct: 324 IDECSFERTCDH--ICINSPGSFQCLCHRGYILYGTTHCGDVDECSM-SNGSCDQ--GCV 378
Query: 93 NTPGGFYCICLEGYRATNNNK 113
NT G + C+C G R N K
Sbjct: 379 NTKGSYECVCPPGRRLHWNGK 399
>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
Length = 742
Score = 82.8 bits (203), Expect = 1e-15
Identities = 47/141 (33%), Positives = 62/141 (43%), Gaps = 12/141 (8%)
Query: 29 GAPGPDGLDVCATCHEHATCQQREGKKICICNYGF------VGNGRTQCVDKNECQFGAT 82
GA D C ++++C C CN GF + C D NEC +
Sbjct: 17 GAETQDSRGCARWCPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSK 73
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSG--LCRHGGR 140
+ CG + C NT G + C+C GY + KTF C D+DEC SG C
Sbjct: 74 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECS-SGQHQCDSSTV 132
Query: 141 CVNTHGSFECYCMDGYLPRNG 161
C NT GS+ C C G+ PR+G
Sbjct: 133 CFNTVGSYSCRCRPGWKPRHG 153
Score = 52.8 bits (125), Expect = 1e-06
Identities = 45/166 (27%), Positives = 68/166 (40%), Gaps = 14/166 (8%)
Query: 80 GATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL--CRH 137
G C ++SC N C C G+ + + I C DI+EC C
Sbjct: 25 GCARWCPQNSSCVNATA---CRCNPGFSSFSE---IITTPTETCDDINECATPSKVSCGK 78
Query: 138 GGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPD-GYIIGNYT 195
C NT GS++C C GY P +G + F ++ T C ++D C + D + N
Sbjct: 79 FSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENT-CQDVDECSSGQHQCDSSTVCFNTV 137
Query: 196 SSLGSQVR--YACREGFFSVPEDTVSSCTGLGTWESPK-LHCQEIN 238
S + R + R G + +DTV TW P +H Q ++
Sbjct: 138 GSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLS 183
>gi|194328809 latent transforming growth factor beta binding protein
3 isoform 1 [Homo sapiens]
Length = 1303
Score = 81.6 bits (200), Expect = 2e-15
Identities = 57/168 (33%), Positives = 73/168 (43%), Gaps = 33/168 (19%)
Query: 48 CQQREGKKICICNYGFVG--NGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEG 105
C+ G C C G+ +GR+ C+D +EC+ G VC N C NTPG F C CL G
Sbjct: 759 CENLPGSFRCTCAQGYAPAPDGRS-CLDVDECEAGD--VCDNGI-CSNTPGSFQCQCLSG 814
Query: 106 YRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPF 165
Y + D + C DIDEC+ C GG C+NT+GS+ C C G
Sbjct: 815 YH--------LSRDRSHCEDIDECDFPAAC-IGGDCINTNGSYRCLCPQG---------- 855
Query: 166 HPTTDATSCTEID-CGTPPE--VPDGYIIGNYTSSLGSQVRYACREGF 210
H C +ID C P +P G +L C EGF
Sbjct: 856 HRLVGGRKCQDIDECSQDPSLCLPHG-----ACKNLQGSYVCVCDEGF 898
Score = 78.6 bits (192), Expect = 2e-14
Identities = 52/162 (32%), Positives = 68/162 (41%), Gaps = 38/162 (23%)
Query: 30 APGPDGL-----------DVCATCHEHATCQQREGKKICICNYGF-VGNGRTQCVDKNEC 77
AP PDG DVC ++ C G C C G+ + R+ C D +EC
Sbjct: 775 APAPDGRSCLDVDECEAGDVC----DNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC 830
Query: 78 QFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS-GLCR 136
F A + G+ C NT G + C+C +G+R K C DIDEC LC
Sbjct: 831 DFPAACIGGD---CINTNGSYRCLCPQGHRLVGGRK---------CQDIDECSQDPSLCL 878
Query: 137 HGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID 178
G C N GS+ C C +G F PT D C E++
Sbjct: 879 PHGACKNLQGSYVCVCDEG---------FTPTQDQHGCEEVE 911
Score = 75.5 bits (184), Expect = 2e-13
Identities = 54/171 (31%), Positives = 71/171 (41%), Gaps = 24/171 (14%)
Query: 45 HATCQQREGKKICICNYGFVGNGRTQ-CVDKNECQFGATLVCG-NHTSCHNTPGGFYCIC 102
H C C CN G+ + + + CVD NEC+ CG C NT G + C C
Sbjct: 587 HGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP---CGPGRGICMNTGGSYNCHC 643
Query: 103 LEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGP 162
GYR + G C D++EC LC GG C+N G ++C C GY +
Sbjct: 644 NRGYRL------HVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASR 697
Query: 163 EPFHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFS 212
P C +ID C P PD G + GS AC+ G+ S
Sbjct: 698 PPV--------CEDIDECRDPSSCPD----GKCENKPGSFKCIACQPGYRS 736
Score = 74.3 bits (181), Expect = 4e-13
Identities = 70/267 (26%), Positives = 90/267 (33%), Gaps = 74/267 (27%)
Query: 48 CQQREGKKICICNYGF---VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLE 104
C G C CN G+ VG G CVD NEC +CG+ C N PG + C C
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC--AKPHLCGDGGFCINFPGHYKCNCYP 689
Query: 105 GYRATNN-----------------------NKT-----------FIPNDGTFCTDIDECE 130
GYR + NK + G C D++EC
Sbjct: 690 GYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECA 749
Query: 131 VSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYI 190
C G C N GSF C C GY P D SC ++D +V D I
Sbjct: 750 EGSPCSPGW-CENLPGSFRCTCAQGYA---------PAPDGRSCLDVDECEAGDVCDNGI 799
Query: 191 IGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEIN-CGNPPEMRHAI 249
N S Q C G+ + HC++I+ C P A
Sbjct: 800 CSNTPGSFQCQ----CLSGYH---------------LSRDRSHCEDIDECDFP-----AA 835
Query: 250 LVGNHSSRLGGVARYVCQEGFESPGGK 276
+G G R +C +G GG+
Sbjct: 836 CIGGDCINTNGSYRCLCPQGHRLVGGR 862
Score = 60.1 bits (144), Expect = 7e-09
Identities = 42/136 (30%), Positives = 59/136 (43%), Gaps = 14/136 (10%)
Query: 29 GAPGPDGLDVCAT-----CHEHATCQQREGKKICICNYGFVGNGRT-QCVDKNECQFGAT 82
G P +D C C E + G + C C GF +G +CVD +EC +
Sbjct: 987 GIPAHRDIDECMLFGSEICKEGKCVNTQPGYE-CYCKQGFYYDGNLLECVDVDECLDESN 1045
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCV 142
C N C NT GG+ C C + + + + D+DEC+ CR G RCV
Sbjct: 1046 --CRNGV-CENTRGGYRCACTPPAEYSPAQRQCLSPEEM---DVDECQDPAACRPG-RCV 1098
Query: 143 NTHGSFECYCMDGYLP 158
N GS+ C C ++P
Sbjct: 1099 NLPGSYRCECRPPWVP 1114
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/152 (28%), Positives = 63/152 (41%), Gaps = 40/152 (26%)
Query: 42 CHEHATCQQREGKKICICNYGFVGN-GRTQCVD------KNEC--QFGATLVC------- 85
C H C+ +G +C+C+ GF + C + K EC F T+ C
Sbjct: 877 CLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATN 936
Query: 86 --------------GNHTSCHNTP----GGFYCICLEGYRATNNNKTFIPNDGTFC-TDI 126
G+H + P F+ +C +G T +N I N G DI
Sbjct: 937 VTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNN--IVNYGIPAHRDI 994
Query: 127 DECEVSG--LCRHGGRCVNTHGSFECYCMDGY 156
DEC + G +C+ G +CVNT +ECYC G+
Sbjct: 995 DECMLFGSEICKEG-KCVNTQPGYECYCKQGF 1025
Score = 48.9 bits (115), Expect = 2e-05
Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 10/55 (18%)
Query: 102 CLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGY 156
C +GY+ N+ T C DI+EC + G+CRHG C+N GS+ C C G+
Sbjct: 341 CPQGYKRLNS---------THCQDINECAMPGVCRHGD-CLNNPGSYRCVCPPGH 385
Score = 46.2 bits (108), Expect = 1e-04
Identities = 31/87 (35%), Positives = 37/87 (42%), Gaps = 18/87 (20%)
Query: 73 DKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEV- 131
D +EC+ V G C PGG C C G++ + C DIDEC
Sbjct: 1217 DSDECR----CVSGR---CVPRPGGAVCECPGGFQLDASRAR--------CVDIDECREL 1261
Query: 132 --SGLCRHGGRCVNTHGSFECYCMDGY 156
GL RCVNT GSF C C G+
Sbjct: 1262 NQRGLLCKSERCVNTSGSFRCVCKAGF 1288
Score = 43.9 bits (102), Expect = 5e-04
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 23 LARGAAGAPGPDGLDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGAT 82
L+R + D D A C C G C+C G G +C D +EC +
Sbjct: 817 LSRDRSHCEDIDECDFPAACIG-GDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPS 875
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNN 111
L C H +C N G + C+C EG+ T +
Sbjct: 876 L-CLPHGACKNLQGSYVCVCDEGFTPTQD 903
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 48 CQQREGKKICICNYGF-VGNGRTQCVDKNECQF--GATLVCGNHTSCHNTPGGFYCICLE 104
C R G +C C GF + R +CVD +EC+ L+C + C NT G F C+C
Sbjct: 1228 CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSER-CVNTSGSFRCVCKA 1286
Query: 105 GYRATNNNKTFIP 117
G+ + + +P
Sbjct: 1287 GFARSRPHGACVP 1299
Score = 37.0 bits (84), Expect = 0.067
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 3/48 (6%)
Query: 59 CNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C G+ T C D NEC VC H C N PG + C+C G+
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPG--VC-RHGDCLNNPGSYRCVCPPGH 385
Score = 33.1 bits (74), Expect = 0.97
Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 5/61 (8%)
Query: 121 TFCTDIDECEVS-GLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDC 179
T T+ DEC ++ +C HG CV + C+C GY R+ P+ + D C C
Sbjct: 570 TQVTETDECRLNQNICGHG-ECVPGPPDYSCHCNPGY--RSHPQHRY-CVDVNECEAEPC 625
Query: 180 G 180
G
Sbjct: 626 G 626
>gi|18497288 latent transforming growth factor beta binding protein
3 isoform 2 [Homo sapiens]
Length = 1256
Score = 81.6 bits (200), Expect = 2e-15
Identities = 57/168 (33%), Positives = 73/168 (43%), Gaps = 33/168 (19%)
Query: 48 CQQREGKKICICNYGFVG--NGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEG 105
C+ G C C G+ +GR+ C+D +EC+ G VC N C NTPG F C CL G
Sbjct: 759 CENLPGSFRCTCAQGYAPAPDGRS-CLDVDECEAGD--VCDNGI-CSNTPGSFQCQCLSG 814
Query: 106 YRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPF 165
Y + D + C DIDEC+ C GG C+NT+GS+ C C G
Sbjct: 815 YH--------LSRDRSHCEDIDECDFPAAC-IGGDCINTNGSYRCLCPQG---------- 855
Query: 166 HPTTDATSCTEID-CGTPPE--VPDGYIIGNYTSSLGSQVRYACREGF 210
H C +ID C P +P G +L C EGF
Sbjct: 856 HRLVGGRKCQDIDECSQDPSLCLPHG-----ACKNLQGSYVCVCDEGF 898
Score = 78.6 bits (192), Expect = 2e-14
Identities = 52/162 (32%), Positives = 68/162 (41%), Gaps = 38/162 (23%)
Query: 30 APGPDGL-----------DVCATCHEHATCQQREGKKICICNYGF-VGNGRTQCVDKNEC 77
AP PDG DVC ++ C G C C G+ + R+ C D +EC
Sbjct: 775 APAPDGRSCLDVDECEAGDVC----DNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC 830
Query: 78 QFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVS-GLCR 136
F A + G+ C NT G + C+C +G+R K C DIDEC LC
Sbjct: 831 DFPAACIGGD---CINTNGSYRCLCPQGHRLVGGRK---------CQDIDECSQDPSLCL 878
Query: 137 HGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID 178
G C N GS+ C C +G F PT D C E++
Sbjct: 879 PHGACKNLQGSYVCVCDEG---------FTPTQDQHGCEEVE 911
Score = 75.5 bits (184), Expect = 2e-13
Identities = 54/171 (31%), Positives = 71/171 (41%), Gaps = 24/171 (14%)
Query: 45 HATCQQREGKKICICNYGFVGNGRTQ-CVDKNECQFGATLVCG-NHTSCHNTPGGFYCIC 102
H C C CN G+ + + + CVD NEC+ CG C NT G + C C
Sbjct: 587 HGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP---CGPGRGICMNTGGSYNCHC 643
Query: 103 LEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGP 162
GYR + G C D++EC LC GG C+N G ++C C GY +
Sbjct: 644 NRGYRL------HVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASR 697
Query: 163 EPFHPTTDATSCTEID-CGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFS 212
P C +ID C P PD G + GS AC+ G+ S
Sbjct: 698 PPV--------CEDIDECRDPSSCPD----GKCENKPGSFKCIACQPGYRS 736
Score = 74.3 bits (181), Expect = 4e-13
Identities = 70/267 (26%), Positives = 90/267 (33%), Gaps = 74/267 (27%)
Query: 48 CQQREGKKICICNYGF---VGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLE 104
C G C CN G+ VG G CVD NEC +CG+ C N PG + C C
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC--AKPHLCGDGGFCINFPGHYKCNCYP 689
Query: 105 GYRATNN-----------------------NKT-----------FIPNDGTFCTDIDECE 130
GYR + NK + G C D++EC
Sbjct: 690 GYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECA 749
Query: 131 VSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYI 190
C G C N GSF C C GY P D SC ++D +V D I
Sbjct: 750 EGSPCSPGW-CENLPGSFRCTCAQGYA---------PAPDGRSCLDVDECEAGDVCDNGI 799
Query: 191 IGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEIN-CGNPPEMRHAI 249
N S Q C G+ + HC++I+ C P A
Sbjct: 800 CSNTPGSFQCQ----CLSGYH---------------LSRDRSHCEDIDECDFP-----AA 835
Query: 250 LVGNHSSRLGGVARYVCQEGFESPGGK 276
+G G R +C +G GG+
Sbjct: 836 CIGGDCINTNGSYRCLCPQGHRLVGGR 862
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/152 (28%), Positives = 63/152 (41%), Gaps = 40/152 (26%)
Query: 42 CHEHATCQQREGKKICICNYGFVGN-GRTQCVD------KNEC--QFGATLVC------- 85
C H C+ +G +C+C+ GF + C + K EC F T+ C
Sbjct: 877 CLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATN 936
Query: 86 --------------GNHTSCHNTP----GGFYCICLEGYRATNNNKTFIPNDGTFC-TDI 126
G+H + P F+ +C +G T +N I N G DI
Sbjct: 937 VTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNN--IVNYGIPAHRDI 994
Query: 127 DECEVSG--LCRHGGRCVNTHGSFECYCMDGY 156
DEC + G +C+ G +CVNT +ECYC G+
Sbjct: 995 DECMLFGSEICKEG-KCVNTQPGYECYCKQGF 1025
Score = 50.1 bits (118), Expect = 8e-06
Identities = 34/117 (29%), Positives = 49/117 (41%), Gaps = 17/117 (14%)
Query: 38 VCATCHEHATCQQREG--KKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTP 95
V ++ H+ C +G + I NYG + D +EC + +C C NT
Sbjct: 961 VYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHR-----DIDECMLFGSEIC-KEGKCVNTQ 1014
Query: 96 GGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYC 152
G+ C C +G+ N C D+DEC CR+ G C NT G + C C
Sbjct: 1015 PGYECYCKQGFYYDGNLLE--------CVDVDECLDESNCRN-GVCENTRGGYRCAC 1062
Score = 48.9 bits (115), Expect = 2e-05
Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 10/55 (18%)
Query: 102 CLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGY 156
C +GY+ N+ T C DI+EC + G+CRHG C+N GS+ C C G+
Sbjct: 341 CPQGYKRLNS---------THCQDINECAMPGVCRHGD-CLNNPGSYRCVCPPGH 385
Score = 46.2 bits (108), Expect = 1e-04
Identities = 31/87 (35%), Positives = 37/87 (42%), Gaps = 18/87 (20%)
Query: 73 DKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEV- 131
D +EC+ V G C PGG C C G++ + C DIDEC
Sbjct: 1170 DSDECR----CVSGR---CVPRPGGAVCECPGGFQLDASRAR--------CVDIDECREL 1214
Query: 132 --SGLCRHGGRCVNTHGSFECYCMDGY 156
GL RCVNT GSF C C G+
Sbjct: 1215 NQRGLLCKSERCVNTSGSFRCVCKAGF 1241
Score = 43.9 bits (102), Expect = 5e-04
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 23 LARGAAGAPGPDGLDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGAT 82
L+R + D D A C C G C+C G G +C D +EC +
Sbjct: 817 LSRDRSHCEDIDECDFPAACIG-GDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPS 875
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNN 111
L C H +C N G + C+C EG+ T +
Sbjct: 876 L-CLPHGACKNLQGSYVCVCDEGFTPTQD 903
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 48 CQQREGKKICICNYGF-VGNGRTQCVDKNECQF--GATLVCGNHTSCHNTPGGFYCICLE 104
C R G +C C GF + R +CVD +EC+ L+C + C NT G F C+C
Sbjct: 1181 CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSER-CVNTSGSFRCVCKA 1239
Query: 105 GYRATNNNKTFIP 117
G+ + + +P
Sbjct: 1240 GFARSRPHGACVP 1252
Score = 37.0 bits (84), Expect = 0.067
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 3/48 (6%)
Query: 59 CNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGY 106
C G+ T C D NEC VC H C N PG + C+C G+
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPG--VC-RHGDCLNNPGSYRCVCPPGH 385
Score = 33.1 bits (74), Expect = 0.97
Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 5/61 (8%)
Query: 121 TFCTDIDECEVS-GLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDC 179
T T+ DEC ++ +C HG CV + C+C GY R+ P+ + D C C
Sbjct: 570 TQVTETDECRLNQNICGHG-ECVPGPPDYSCHCNPGY--RSHPQHRY-CVDVNECEAEPC 625
Query: 180 G 180
G
Sbjct: 626 G 626
>gi|23397693 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform g [Homo sapiens]
Length = 719
Score = 81.3 bits (199), Expect = 3e-15
Identities = 47/141 (33%), Positives = 61/141 (43%), Gaps = 12/141 (8%)
Query: 29 GAPGPDGLDVCATCHEHATCQQREGKKICICNYGF------VGNGRTQCVDKNECQFGAT 82
GA D C + ++C C CN GF + C D NEC +
Sbjct: 20 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 76
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSG--LCRHGGR 140
+ CG + C NT G + C+C GY + KTF C D+DEC SG C
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECS-SGQHQCDSSTV 135
Query: 141 CVNTHGSFECYCMDGYLPRNG 161
C NT GS+ C C G+ PR+G
Sbjct: 136 CFNTVGSYSCRCRPGWKPRHG 156
Score = 51.2 bits (121), Expect = 3e-06
Identities = 45/166 (27%), Positives = 67/166 (40%), Gaps = 14/166 (8%)
Query: 80 GATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL--CRH 137
G C +SC N C C G+ + + I C DI+EC C
Sbjct: 28 GCARWCPQDSSCVNATA---CRCNPGFSSFSE---IITTPMETCDDINECATLSKVSCGK 81
Query: 138 GGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPD-GYIIGNYT 195
C NT GS++C C GY P +G + F ++ T C ++D C + D + N
Sbjct: 82 FSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENT-CQDVDECSSGQHQCDSSTVCFNTV 140
Query: 196 SSLGSQVR--YACREGFFSVPEDTVSSCTGLGTWESPK-LHCQEIN 238
S + R + R G + +DTV TW P +H Q ++
Sbjct: 141 GSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLS 186
>gi|23397685 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform c [Homo sapiens]
Length = 730
Score = 81.3 bits (199), Expect = 3e-15
Identities = 47/141 (33%), Positives = 61/141 (43%), Gaps = 12/141 (8%)
Query: 29 GAPGPDGLDVCATCHEHATCQQREGKKICICNYGF------VGNGRTQCVDKNECQFGAT 82
GA D C + ++C C CN GF + C D NEC +
Sbjct: 20 GAETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSK 76
Query: 83 LVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSG--LCRHGGR 140
+ CG + C NT G + C+C GY + KTF C D+DEC SG C
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECS-SGQHQCDSSTV 135
Query: 141 CVNTHGSFECYCMDGYLPRNG 161
C NT GS+ C C G+ PR+G
Sbjct: 136 CFNTVGSYSCRCRPGWKPRHG 156
Score = 51.2 bits (121), Expect = 3e-06
Identities = 45/166 (27%), Positives = 67/166 (40%), Gaps = 14/166 (8%)
Query: 80 GATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL--CRH 137
G C +SC N C C G+ + + I C DI+EC C
Sbjct: 28 GCARWCPQDSSCVNATA---CRCNPGFSSFSE---IITTPMETCDDINECATLSKVSCGK 81
Query: 138 GGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEID-CGTPPEVPD-GYIIGNYT 195
C NT GS++C C GY P +G + F ++ T C ++D C + D + N
Sbjct: 82 FSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENT-CQDVDECSSGQHQCDSSTVCFNTV 140
Query: 196 SSLGSQVR--YACREGFFSVPEDTVSSCTGLGTWESPK-LHCQEIN 238
S + R + R G + +DTV TW P +H Q ++
Sbjct: 141 GSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLS 186
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,719,379
Number of Sequences: 37866
Number of extensions: 1640907
Number of successful extensions: 7164
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 165
Number of HSP's that attempted gapping in prelim test: 4076
Number of HSP's gapped (non-prelim): 1440
length of query: 747
length of database: 18,247,518
effective HSP length: 110
effective length of query: 637
effective length of database: 14,082,258
effective search space: 8970398346
effective search space used: 8970398346
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.