Guide to the Human Genome
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Search of human proteins with 42476204

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]
         (248 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]                   503   e-143
gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]                   473   e-134
gi|21264578 tetraspan 1 [Homo sapiens]                                138   5e-33
gi|5729941 tetraspanin 9 [Homo sapiens]                               135   3e-32
gi|122937466 tetraspanin 11 [Homo sapiens]                            133   2e-31
gi|87159824 CD151 antigen [Homo sapiens]                              132   4e-31
gi|87159822 CD151 antigen [Homo sapiens]                              132   4e-31
gi|21237751 CD151 antigen [Homo sapiens]                              132   4e-31
gi|21237748 CD151 antigen [Homo sapiens]                              132   4e-31
gi|68800005 tetraspanin 4 isoform a [Homo sapiens]                    125   4e-29
gi|4507543 tetraspanin 4 isoform a [Homo sapiens]                     125   4e-29
gi|68800018 tetraspanin 4 isoform a [Homo sapiens]                    125   4e-29
gi|68800024 tetraspanin 4 isoform a [Homo sapiens]                    125   4e-29
gi|68800011 tetraspanin 4 isoform a [Homo sapiens]                    125   4e-29
gi|68799997 tetraspanin 4 isoform a [Homo sapiens]                    125   4e-29
gi|4502693 CD9 antigen [Homo sapiens]                                 115   4e-26
gi|10834972 CD53 antigen [Homo sapiens]                               114   8e-26
gi|91106727 CD53 antigen [Homo sapiens]                               114   8e-26
gi|4757944 CD81 antigen [Homo sapiens]                                111   7e-25
gi|21265104 tetraspanin 7 [Homo sapiens]                              108   3e-24
gi|4504813 CD82 antigen isoform 1 [Homo sapiens]                      108   3e-24
gi|54859560 transmembrane 4 superfamily member 17 isoform a [Hom...   106   2e-23
gi|50511934 transmembrane 4 superfamily member 17 isoform b [Hom...   106   2e-23
gi|54859505 transmembrane 4 superfamily member 17 isoform c [Hom...   105   3e-23
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]        105   3e-23
gi|4502679 CD63 antigen isoform A [Homo sapiens]                      105   5e-23
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]                  104   8e-23
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]        103   1e-22
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]       103   1e-22
gi|91199546 CD63 antigen isoform B [Homo sapiens]                      98   8e-21

>gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]
          Length = 248

 Score =  503 bits (1295), Expect = e-143
 Identities = 248/248 (100%), Positives = 248/248 (100%)

Query: 1   MEGDCLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLA 60
           MEGDCLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLA
Sbjct: 1   MEGDCLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLA 60

Query: 61  MGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKE 120
           MGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKE
Sbjct: 61  MGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKE 120

Query: 121 LTKHYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRRE 180
           LTKHYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRRE
Sbjct: 121 LTKHYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRRE 180

Query: 181 PQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFA 240
           PQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFA
Sbjct: 181 PQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFA 240

Query: 241 MCLFRGIQ 248
           MCLFRGIQ
Sbjct: 241 MCLFRGIQ 248


>gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]
          Length = 267

 Score =  473 bits (1217), Expect = e-134
 Identities = 232/233 (99%), Positives = 233/233 (100%)

Query: 1   MEGDCLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLA 60
           MEGDCLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLA
Sbjct: 1   MEGDCLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLA 60

Query: 61  MGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKE 120
           MGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKE
Sbjct: 61  MGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKE 120

Query: 121 LTKHYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRRE 180
           LTKHYQGNNDTD+FSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRRE
Sbjct: 121 LTKHYQGNNDTDVFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRRE 180

Query: 181 PQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIE 233
           PQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIE
Sbjct: 181 PQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIE 233


>gi|21264578 tetraspan 1 [Homo sapiens]
          Length = 241

 Score =  138 bits (347), Expect = 5e-33
 Identities = 84/253 (33%), Positives = 127/253 (50%), Gaps = 23/253 (9%)

Query: 5   CLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPL------LLTGAYIL 58
           C S +K +M +FN  IFL GA LLA+GIWV +D   F +I    PL       +   Y L
Sbjct: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFG--PLSSSAMQFVNVGYFL 60

Query: 59  LAMGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIF---RENLTRE 115
           +A G ++F LGFLGC GA  E+KC L+ FF  +L+IF+AE++AA++A ++    E+    
Sbjct: 61  IAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTL 120

Query: 116 FFTKELTKHYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEA 175
                + K Y    D   F+  WN+ M    CCG     DF+ +  F+    ++   P  
Sbjct: 121 LVVPAIKKDYGSQED---FTQVWNTTMKGLKCCGFTNYTDFEDSPYFK----ENSAFPPF 173

Query: 176 CCRREPQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELF 235
           CC     +      + E C   ++     +GC+  +L    T     G +A G+  +EL 
Sbjct: 174 CCNDNVTN-----TANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELA 228

Query: 236 AMIFAMCLFRGIQ 248
           AMI +M L+  +Q
Sbjct: 229 AMIVSMYLYCNLQ 241


>gi|5729941 tetraspanin 9 [Homo sapiens]
          Length = 239

 Score =  135 bits (341), Expect = 3e-32
 Identities = 83/251 (33%), Positives = 127/251 (50%), Gaps = 25/251 (9%)

Query: 1   MEGDCLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLA 60
           M   CL C+KY+MF+FN   +L G  LL +GIW+ V    F     + P L + A +++A
Sbjct: 1   MARGCLCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSL-SAANLVIA 59

Query: 61  MGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIF----RENLTREF 116
           +G ++ + GFLGC GA++ENKCLLL FF+ +L+I LAEL   IL F++     EN  ++ 
Sbjct: 60  IGTIVMVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDL 119

Query: 117 FTKELTKHYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEAC 176
             KE    Y   N+  + +A WN +     CCGV    D+          L    VP+ C
Sbjct: 120 --KEGLLLYHTENNVGLKNA-WNIIQAEMRCCGVTDYTDW-------YPVLGENTVPDRC 169

Query: 177 CRREPQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFA 236
           C    Q           C    +  L + GCY  +   F+   ++ G + + +L +++  
Sbjct: 170 CMENSQG----------CGRNATTPLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILG 219

Query: 237 MIFAMCLFRGI 247
           M F+M LF+ I
Sbjct: 220 MAFSMTLFQHI 230


>gi|122937466 tetraspanin 11 [Homo sapiens]
          Length = 253

 Score =  133 bits (334), Expect = 2e-31
 Identities = 74/243 (30%), Positives = 135/243 (55%), Gaps = 12/243 (4%)

Query: 9   MKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLLFLL 68
           +KYL+FVFNFF ++GGA +LA+GIW +V+ +G+  ++A++      AYIL+  G L+ + 
Sbjct: 16  LKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASS-TFAASAYILIFAGVLVMVT 74

Query: 69  GFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLT---REFFTKELTKHY 125
           GFLG    + E K  L  +F  +L+IFL EL A +LA ++ + L+   ++   + L ++Y
Sbjct: 75  GFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENY 134

Query: 126 QGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSRD 185
                T I +A+ + +   F CCG N   D++ ++   L   +  +VP++CC+       
Sbjct: 135 GQPGATQI-TASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKT------ 187

Query: 186 GVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCLFR 245
            V++   +     +++  + GC T +      ++ L GA+ IGV  +++  M+   CL +
Sbjct: 188 -VVVRCGQRAHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHQ 246

Query: 246 GIQ 248
            +Q
Sbjct: 247 RLQ 249


>gi|87159824 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  132 bits (331), Expect = 4e-31
 Identities = 72/244 (29%), Positives = 129/244 (52%), Gaps = 12/244 (4%)

Query: 8   CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLLFL 67
           C+KYL+F +N   +L G  ++A+GIW +   + +  ++A+   L T AYIL+  G ++ +
Sbjct: 15  CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLAT-AYILVVAGTVVMV 73

Query: 68  LGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLT---REFFTKELTKH 124
            G LGCC   +E + LL  +F+ +LIIFL E+ A ILA+ + + L    +E     +TK 
Sbjct: 74  TGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKR 133

Query: 125 YQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSR 184
           Y       + SA  + +   F CCG N  +D++ +   R        VP++CC+      
Sbjct: 134 YHQPGHEAVTSAV-DQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKT----- 187

Query: 185 DGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCLF 244
             V+    +     +++  + GC T +    + ++ + GA+ IG+  +++F MIF  CL+
Sbjct: 188 --VVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLY 245

Query: 245 RGIQ 248
           R ++
Sbjct: 246 RSLK 249


>gi|87159822 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  132 bits (331), Expect = 4e-31
 Identities = 72/244 (29%), Positives = 129/244 (52%), Gaps = 12/244 (4%)

Query: 8   CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLLFL 67
           C+KYL+F +N   +L G  ++A+GIW +   + +  ++A+   L T AYIL+  G ++ +
Sbjct: 15  CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLAT-AYILVVAGTVVMV 73

Query: 68  LGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLT---REFFTKELTKH 124
            G LGCC   +E + LL  +F+ +LIIFL E+ A ILA+ + + L    +E     +TK 
Sbjct: 74  TGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKR 133

Query: 125 YQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSR 184
           Y       + SA  + +   F CCG N  +D++ +   R        VP++CC+      
Sbjct: 134 YHQPGHEAVTSAV-DQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKT----- 187

Query: 185 DGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCLF 244
             V+    +     +++  + GC T +    + ++ + GA+ IG+  +++F MIF  CL+
Sbjct: 188 --VVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLY 245

Query: 245 RGIQ 248
           R ++
Sbjct: 246 RSLK 249


>gi|21237751 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  132 bits (331), Expect = 4e-31
 Identities = 72/244 (29%), Positives = 129/244 (52%), Gaps = 12/244 (4%)

Query: 8   CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLLFL 67
           C+KYL+F +N   +L G  ++A+GIW +   + +  ++A+   L T AYIL+  G ++ +
Sbjct: 15  CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLAT-AYILVVAGTVVMV 73

Query: 68  LGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLT---REFFTKELTKH 124
            G LGCC   +E + LL  +F+ +LIIFL E+ A ILA+ + + L    +E     +TK 
Sbjct: 74  TGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKR 133

Query: 125 YQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSR 184
           Y       + SA  + +   F CCG N  +D++ +   R        VP++CC+      
Sbjct: 134 YHQPGHEAVTSAV-DQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKT----- 187

Query: 185 DGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCLF 244
             V+    +     +++  + GC T +    + ++ + GA+ IG+  +++F MIF  CL+
Sbjct: 188 --VVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLY 245

Query: 245 RGIQ 248
           R ++
Sbjct: 246 RSLK 249


>gi|21237748 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  132 bits (331), Expect = 4e-31
 Identities = 72/244 (29%), Positives = 129/244 (52%), Gaps = 12/244 (4%)

Query: 8   CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLLFL 67
           C+KYL+F +N   +L G  ++A+GIW +   + +  ++A+   L T AYIL+  G ++ +
Sbjct: 15  CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLAT-AYILVVAGTVVMV 73

Query: 68  LGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLT---REFFTKELTKH 124
            G LGCC   +E + LL  +F+ +LIIFL E+ A ILA+ + + L    +E     +TK 
Sbjct: 74  TGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKR 133

Query: 125 YQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSR 184
           Y       + SA  + +   F CCG N  +D++ +   R        VP++CC+      
Sbjct: 134 YHQPGHEAVTSAV-DQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKT----- 187

Query: 185 DGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCLF 244
             V+    +     +++  + GC T +    + ++ + GA+ IG+  +++F MIF  CL+
Sbjct: 188 --VVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLY 245

Query: 245 RGIQ 248
           R ++
Sbjct: 246 RSLK 249


>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  125 bits (313), Expect = 4e-29
 Identities = 73/242 (30%), Positives = 118/242 (48%), Gaps = 21/242 (8%)

Query: 5   CLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGL 64
           CL  +KYLMF FN   +LGG  +L +GIW+      F  + ++ P L + A +L+  G  
Sbjct: 5   CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSL-SAANLLIITGAF 63

Query: 65  LFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTK- 123
           +  +GF+GC GA++ENKCLLL FFL +L++FL E + AIL F + + + R +  ++L K 
Sbjct: 64  VMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDR-YAQQDLKKG 122

Query: 124 -HYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQ 182
            H  G       +  W+ +   F CCGV+   D+           ++  VP++CC     
Sbjct: 123 LHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDW-------FEVYNATRVPDSCC----- 170

Query: 183 SRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMC 242
                L   E C L       K  CY  +    +  +   G   +    +++  + FAM 
Sbjct: 171 -----LEFSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMT 225

Query: 243 LF 244
           ++
Sbjct: 226 MY 227


>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  125 bits (313), Expect = 4e-29
 Identities = 73/242 (30%), Positives = 118/242 (48%), Gaps = 21/242 (8%)

Query: 5   CLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGL 64
           CL  +KYLMF FN   +LGG  +L +GIW+      F  + ++ P L + A +L+  G  
Sbjct: 5   CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSL-SAANLLIITGAF 63

Query: 65  LFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTK- 123
           +  +GF+GC GA++ENKCLLL FFL +L++FL E + AIL F + + + R +  ++L K 
Sbjct: 64  VMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDR-YAQQDLKKG 122

Query: 124 -HYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQ 182
            H  G       +  W+ +   F CCGV+   D+           ++  VP++CC     
Sbjct: 123 LHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDW-------FEVYNATRVPDSCC----- 170

Query: 183 SRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMC 242
                L   E C L       K  CY  +    +  +   G   +    +++  + FAM 
Sbjct: 171 -----LEFSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMT 225

Query: 243 LF 244
           ++
Sbjct: 226 MY 227


>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  125 bits (313), Expect = 4e-29
 Identities = 73/242 (30%), Positives = 118/242 (48%), Gaps = 21/242 (8%)

Query: 5   CLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGL 64
           CL  +KYLMF FN   +LGG  +L +GIW+      F  + ++ P L + A +L+  G  
Sbjct: 5   CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSL-SAANLLIITGAF 63

Query: 65  LFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTK- 123
           +  +GF+GC GA++ENKCLLL FFL +L++FL E + AIL F + + + R +  ++L K 
Sbjct: 64  VMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDR-YAQQDLKKG 122

Query: 124 -HYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQ 182
            H  G       +  W+ +   F CCGV+   D+           ++  VP++CC     
Sbjct: 123 LHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDW-------FEVYNATRVPDSCC----- 170

Query: 183 SRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMC 242
                L   E C L       K  CY  +    +  +   G   +    +++  + FAM 
Sbjct: 171 -----LEFSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMT 225

Query: 243 LF 244
           ++
Sbjct: 226 MY 227


>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  125 bits (313), Expect = 4e-29
 Identities = 73/242 (30%), Positives = 118/242 (48%), Gaps = 21/242 (8%)

Query: 5   CLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGL 64
           CL  +KYLMF FN   +LGG  +L +GIW+      F  + ++ P L + A +L+  G  
Sbjct: 5   CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSL-SAANLLIITGAF 63

Query: 65  LFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTK- 123
           +  +GF+GC GA++ENKCLLL FFL +L++FL E + AIL F + + + R +  ++L K 
Sbjct: 64  VMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDR-YAQQDLKKG 122

Query: 124 -HYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQ 182
            H  G       +  W+ +   F CCGV+   D+           ++  VP++CC     
Sbjct: 123 LHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDW-------FEVYNATRVPDSCC----- 170

Query: 183 SRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMC 242
                L   E C L       K  CY  +    +  +   G   +    +++  + FAM 
Sbjct: 171 -----LEFSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMT 225

Query: 243 LF 244
           ++
Sbjct: 226 MY 227


>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  125 bits (313), Expect = 4e-29
 Identities = 73/242 (30%), Positives = 118/242 (48%), Gaps = 21/242 (8%)

Query: 5   CLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGL 64
           CL  +KYLMF FN   +LGG  +L +GIW+      F  + ++ P L + A +L+  G  
Sbjct: 5   CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSL-SAANLLIITGAF 63

Query: 65  LFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTK- 123
           +  +GF+GC GA++ENKCLLL FFL +L++FL E + AIL F + + + R +  ++L K 
Sbjct: 64  VMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDR-YAQQDLKKG 122

Query: 124 -HYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQ 182
            H  G       +  W+ +   F CCGV+   D+           ++  VP++CC     
Sbjct: 123 LHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDW-------FEVYNATRVPDSCC----- 170

Query: 183 SRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMC 242
                L   E C L       K  CY  +    +  +   G   +    +++  + FAM 
Sbjct: 171 -----LEFSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMT 225

Query: 243 LF 244
           ++
Sbjct: 226 MY 227


>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  125 bits (313), Expect = 4e-29
 Identities = 73/242 (30%), Positives = 118/242 (48%), Gaps = 21/242 (8%)

Query: 5   CLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGL 64
           CL  +KYLMF FN   +LGG  +L +GIW+      F  + ++ P L + A +L+  G  
Sbjct: 5   CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSL-SAANLLIITGAF 63

Query: 65  LFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTK- 123
           +  +GF+GC GA++ENKCLLL FFL +L++FL E + AIL F + + + R +  ++L K 
Sbjct: 64  VMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDR-YAQQDLKKG 122

Query: 124 -HYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQ 182
            H  G       +  W+ +   F CCGV+   D+           ++  VP++CC     
Sbjct: 123 LHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDW-------FEVYNATRVPDSCC----- 170

Query: 183 SRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMC 242
                L   E C L       K  CY  +    +  +   G   +    +++  + FAM 
Sbjct: 171 -----LEFSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMT 225

Query: 243 LF 244
           ++
Sbjct: 226 MY 227


>gi|4502693 CD9 antigen [Homo sapiens]
          Length = 228

 Score =  115 bits (288), Expect = 4e-26
 Identities = 73/243 (30%), Positives = 117/243 (48%), Gaps = 41/243 (16%)

Query: 8   CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGF----REIVAANPLLLTGAYILLAMGG 63
           C+KYL+F FNF  +L G  +LAIG+W+  D        +E    N    TG YIL+  G 
Sbjct: 9   CIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYILIGAGA 68

Query: 64  LLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREF--FTKEL 121
           L+ L+GFLGCCGAV+E++C+L  FF F+L+IF  E++AAI  +  ++ + +E   F K+ 
Sbjct: 69  LMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDT 128

Query: 122 TKHYQGNNDTDIFSATWNSVMITFGCCGV-NGPEDFKFASVFRLLTLDSEEVPEACCRRE 180
               +  ++      T  ++     CCG+  G E F               + + C +++
Sbjct: 129 YNKLKTKDEPQ--RETLKAIHYALNCCGLAGGVEQF---------------ISDICPKKD 171

Query: 181 PQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFA 240
                 V                 + C   I   F+   ++ GA+ IG+  + +F MIF+
Sbjct: 172 VLETFTV-----------------KSCPDAIKEVFDNKFHIIGAVGIGIAVVMIFGMIFS 214

Query: 241 MCL 243
           M L
Sbjct: 215 MIL 217


>gi|10834972 CD53 antigen [Homo sapiens]
          Length = 219

 Score =  114 bits (285), Expect = 8e-26
 Identities = 71/238 (29%), Positives = 112/238 (47%), Gaps = 37/238 (15%)

Query: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLL 65
           L  +KY++F FN   ++ G C+L  GI++++    F  +    P L  G  + + +G ++
Sbjct: 6   LKLLKYVLFFFNLLFWICGCCILGFGIYLLIH-NNFGVLFHNLPSLTLGN-VFVIVGSII 63

Query: 66  FLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHY 125
            ++ FLGC G+++ENKCLL+ FF+ +LII LAE++ AIL F++ + L  E+  K LT   
Sbjct: 64  MVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLN-EYVAKGLTDSI 122

Query: 126 QGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSRD 185
              +  +   A W+S+     CCG+NG  D+                P A C   P  R 
Sbjct: 123 HRYHSDNSTKAAWDSIQSFLQCCGINGTSDWTSG-------------PPASC---PSDR- 165

Query: 186 GVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCL 243
                              +GCY      F +     G + I V  IE+  M FA+ L
Sbjct: 166 -----------------KVEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTL 206


>gi|91106727 CD53 antigen [Homo sapiens]
          Length = 219

 Score =  114 bits (285), Expect = 8e-26
 Identities = 71/238 (29%), Positives = 112/238 (47%), Gaps = 37/238 (15%)

Query: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLL 65
           L  +KY++F FN   ++ G C+L  GI++++    F  +    P L  G  + + +G ++
Sbjct: 6   LKLLKYVLFFFNLLFWICGCCILGFGIYLLIH-NNFGVLFHNLPSLTLGN-VFVIVGSII 63

Query: 66  FLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHY 125
            ++ FLGC G+++ENKCLL+ FF+ +LII LAE++ AIL F++ + L  E+  K LT   
Sbjct: 64  MVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLN-EYVAKGLTDSI 122

Query: 126 QGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSRD 185
              +  +   A W+S+     CCG+NG  D+                P A C   P  R 
Sbjct: 123 HRYHSDNSTKAAWDSIQSFLQCCGINGTSDWTSG-------------PPASC---PSDR- 165

Query: 186 GVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCL 243
                              +GCY      F +     G + I V  IE+  M FA+ L
Sbjct: 166 -----------------KVEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTL 206


>gi|4757944 CD81 antigen [Homo sapiens]
          Length = 236

 Score =  111 bits (277), Expect = 7e-25
 Identities = 74/254 (29%), Positives = 119/254 (46%), Gaps = 38/254 (14%)

Query: 5   CLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVA------ANPLLLTGAYIL 58
           C  C+KYL+FVFNF  +L G  +L + +W+  DP     +        A      G YIL
Sbjct: 6   CTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYIL 65

Query: 59  LAMGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREF-- 116
           +A+G ++  +GFLGC GA++E++CLL  FF  ++I+F  E++A I  F+ ++ + ++   
Sbjct: 66  IAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQ 125

Query: 117 FTKELTKHYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEAC 176
           F  +  +    ++D +   A   +   T  CCG         +S    LT          
Sbjct: 126 FYDQALQQAVVDDDANNAKAVVKTFHETLDCCG---------SSTLTALTTS-------- 168

Query: 177 CRREPQSRDGVLLSREECLLGRSLFLN--KQGCYTVILNTFETYVYLAGALAIGVLAIEL 234
                      +L    C  G ++  N  K+ C+  I + F   +YL G  AI V  I +
Sbjct: 169 -----------VLKNNLCPSGSNIISNLFKEDCHQKIDDLFSGKLYLIGIAAIVVAVIMI 217

Query: 235 FAMIFAMCLFRGIQ 248
           F MI +M L  GI+
Sbjct: 218 FEMILSMVLCCGIR 231


>gi|21265104 tetraspanin 7 [Homo sapiens]
          Length = 249

 Score =  108 bits (271), Expect = 3e-24
 Identities = 64/246 (26%), Positives = 118/246 (47%), Gaps = 20/246 (8%)

Query: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLL 65
           ++C+K L+ +++F  ++ G  LLA+G+W  +    +  ++A N       Y+L+  G  +
Sbjct: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENST--NAPYVLIGTGTTI 69

Query: 66  FLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHY 125
            + G  GC    R +  +L  + +F+ ++FLAEL A I  F+FR  + ++ F +  T   
Sbjct: 70  VVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEI-KDTFLRTYTDAM 128

Query: 126 QGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRRE----P 181
           Q  N  D  S   + V  +  CCGV    ++  +  F         +P +CC  E    P
Sbjct: 129 QTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFL-----EHGIPPSCCMNETDCNP 183

Query: 182 QSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAM 241
           Q    + ++  +        +N++GCY ++ +  ET + +   +A G+   +L  M+ A 
Sbjct: 184 QDLHNLTVAATK--------VNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLAC 235

Query: 242 CLFRGI 247
           CL R I
Sbjct: 236 CLSRFI 241


>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
          Length = 267

 Score =  108 bits (271), Expect = 3e-24
 Identities = 72/265 (27%), Positives = 123/265 (46%), Gaps = 27/265 (10%)

Query: 1   MEGDCLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIV-AANPLLLTGAYILL 59
           M   C+   KY +F+FN   F+ GA +L  G+W++ D + F  ++  ++  L  GAY+ +
Sbjct: 1   MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI 60

Query: 60  AMGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREF--F 117
            +G +  L+GFLGC GAV E +CLL  +F F+L+I +A+++A  L +     L +E    
Sbjct: 61  GVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI 120

Query: 118 TKELTKHYQGNNDTDIFSATWNSVMITFGCCG----VNGPEDFKFASVFRLLTLDSEEVP 173
             EL + Y  + + D     W+ V     CCG     N  ++ +         ++  EV 
Sbjct: 121 VTELIRDYNSSRE-DSLQDAWDYVQAQVKCCGWVSFYNWTDNAEL--------MNRPEVT 171

Query: 174 EACCRREPQSRDGVLLSRE---ECLLGRSLFLN--------KQGCYTVILNTFETYVYLA 222
             C        D  L  R+   E    R+   N        ++GC   +    +  + + 
Sbjct: 172 YPCSCEVKGEEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGII 231

Query: 223 GALAIGVLAIELFAMIFAMCLFRGI 247
             + +GV  IEL  M+ ++CL R +
Sbjct: 232 LGVGVGVAIIELLGMVLSICLCRHV 256


>gi|54859560 transmembrane 4 superfamily member 17 isoform a [Homo
           sapiens]
          Length = 332

 Score =  106 bits (265), Expect = 2e-23
 Identities = 75/259 (28%), Positives = 119/259 (45%), Gaps = 25/259 (9%)

Query: 8   CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLL-LTGAYILLAMGGLLF 66
           C KY +F FN   ++ GA  LAIG+W   +      I A   L  L   ++ + +GG++ 
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMS 75

Query: 67  LLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTRE--FFTKELTKH 124
           +LGF GC GA+REN  LL FF +F+ +IF  EL+  ILAF+F++ +  +   F     K 
Sbjct: 76  VLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA 135

Query: 125 YQGNND----TDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEE----VPEAC 176
           Y+ + D     D     W+       CCG  GP D+     F    L+       VP +C
Sbjct: 136 YRDDIDLQNLIDFAQEYWS-------CCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSC 188

Query: 177 CRREP-------QSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGV 229
           C R+P       Q    V L      L +  F++ +GC        +  + +   + +G+
Sbjct: 189 CVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGI 248

Query: 230 LAIELFAMIFAMCLFRGIQ 248
             +++F +  A  L   I+
Sbjct: 249 ALLQIFGICLAQNLVSDIK 267


>gi|50511934 transmembrane 4 superfamily member 17 isoform b [Homo
           sapiens]
          Length = 329

 Score =  106 bits (264), Expect = 2e-23
 Identities = 75/258 (29%), Positives = 122/258 (47%), Gaps = 26/258 (10%)

Query: 8   CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLL-LTGAYILLAMGGLLF 66
           C KY +F FN   ++ GA  LAIG+W   +      I A   L  L   ++ + +GG++ 
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMS 75

Query: 67  LLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTRE--FFTKELTKH 124
           +LGF GC GA+REN  LL FF +F+ +IF  EL+  ILAF+F++ +  +   F     K 
Sbjct: 76  VLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA 135

Query: 125 YQGNND----TDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEE----VPEAC 176
           Y+ + D     D     W+       CCG  GP D+     F    L+       VP +C
Sbjct: 136 YRDDIDLQNLIDFAQEYWS-------CCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSC 188

Query: 177 CRREPQSRDGVLLS------REECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVL 230
           C R+P   + VL +      R +  L +  F++ +GC        +  + +   + +G+ 
Sbjct: 189 CVRDP--AEDVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIA 246

Query: 231 AIELFAMIFAMCLFRGIQ 248
            +++F +  A  L   I+
Sbjct: 247 LLQIFGICLAQNLVSDIK 264


>gi|54859505 transmembrane 4 superfamily member 17 isoform c [Homo
           sapiens]
          Length = 266

 Score =  105 bits (263), Expect = 3e-23
 Identities = 74/254 (29%), Positives = 117/254 (46%), Gaps = 25/254 (9%)

Query: 8   CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLL-LTGAYILLAMGGLLF 66
           C KY +F FN   ++ GA  LAIG+W   +      I A   L  L   ++ + +GG++ 
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMS 75

Query: 67  LLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTRE--FFTKELTKH 124
           +LGF GC GA+REN  LL FF +F+ +IF  EL+  ILAF+F++ +  +   F     K 
Sbjct: 76  VLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA 135

Query: 125 YQGNND----TDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEE----VPEAC 176
           Y+ + D     D     W+       CCG  GP D+     F    L+       VP +C
Sbjct: 136 YRDDIDLQNLIDFAQEYWS-------CCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSC 188

Query: 177 CRREP-------QSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGV 229
           C R+P       Q    V L      L +  F++ +GC        +  + +   + +G+
Sbjct: 189 CVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGI 248

Query: 230 LAIELFAMIFAMCL 243
             +++F +  A  L
Sbjct: 249 ALLQIFGICLAQNL 262


>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
          Length = 245

 Score =  105 bits (263), Expect = 3e-23
 Identities = 62/243 (25%), Positives = 112/243 (46%), Gaps = 20/243 (8%)

Query: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLL 65
           ++C K ++ ++ F  ++ G  LLA+GIW  V    +  ++  N       ++L+A G ++
Sbjct: 14  ITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLL--NEKATNVPFVLIATGTVI 71

Query: 66  FLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHY 125
            LLG  GC    R +  +L  + +F+ ++FL EL AAI+ F+FR  +   F         
Sbjct: 72  ILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALK 131

Query: 126 QGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSRD 185
           Q N+  D  S   + +  T  CCGV    D+   + +       +  P++CC+       
Sbjct: 132 QYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYY-----SEKGFPKSCCK------- 179

Query: 186 GVLLSREECLLGRSL-FLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCLF 244
                 E+C   R    +N +GC+  ++   E+ + +   ++ GV   +L  +  A CL 
Sbjct: 180 -----LEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLS 234

Query: 245 RGI 247
           R I
Sbjct: 235 RAI 237


>gi|4502679 CD63 antigen isoform A [Homo sapiens]
          Length = 238

 Score =  105 bits (261), Expect = 5e-23
 Identities = 66/245 (26%), Positives = 124/245 (50%), Gaps = 21/245 (8%)

Query: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLL 65
           + C+K+L++V           L+A+G+   +       I  A P  L    +++A+G  L
Sbjct: 7   MKCVKFLLYVLLLAFCACAVGLIAVGVGAQL-VLSQTIIQGATPGSLLPV-VIIAVGVFL 64

Query: 66  FLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFT--KELTK 123
           FL+ F+GCCGA +EN CL++ F +F+ +I L E++AAI  ++FR+ +  EF    ++  +
Sbjct: 65  FLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQME 124

Query: 124 HYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQS 183
           +Y  NN T   ++  + +   F CCG     D++     ++ ++    VP++CC      
Sbjct: 125 NYPKNNHT---ASILDRMQADFKCCGAANYTDWE-----KIPSMSKNRVPDSCCINVTVG 176

Query: 184 RDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCL 243
             G+  + +         ++K+GC   I       V +  A A+G+  +E+  ++FA CL
Sbjct: 177 -CGINFNEKA--------IHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCL 227

Query: 244 FRGIQ 248
            + I+
Sbjct: 228 VKSIR 232


>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
          Length = 270

 Score =  104 bits (259), Expect = 8e-23
 Identities = 75/265 (28%), Positives = 127/265 (47%), Gaps = 35/265 (13%)

Query: 6   LSCM-KYLMFVFNFFIFLGGACLLAIGIW------VMVDPTGFREIVAANPLLLTGAYIL 58
           +SC  KYL+F +N   +L G   L +G+W      V+ D T    +   +P++L     +
Sbjct: 11  VSCWYKYLLFSYNIIFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVL-----V 65

Query: 59  LAMGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRE---NLTRE 115
           L +G ++F LGF GC GA+REN CLL FF   I++IF  EL+ A+LAF+F++   +  RE
Sbjct: 66  LMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFRE 125

Query: 116 FFTKELTKHYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRL----LTLDSEE 171
           FF   +  +    +D D+ +   +S+     CCG  GPED+     F       + +   
Sbjct: 126 FFESNIKSY---RDDIDLQNLI-DSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCG 181

Query: 172 VPEACCRREPQSRDGVLLSREECLLGRSLFLNK--------QGCYTVILNTFETYVYLAG 223
           VP +CC  +P  +    +   +C     + L          +GC   + +     +Y+  
Sbjct: 182 VPFSCCVPDPAQK----VVNTQCGYDVRIQLKSKWDESIFTKGCIQALESWLPRNIYIVA 237

Query: 224 ALAIGVLAIELFAMIFAMCLFRGIQ 248
            + I +  +++F +  A  L   I+
Sbjct: 238 GVFIAISLLQIFGIFLARTLISDIE 262


>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
          Length = 237

 Score =  103 bits (258), Expect = 1e-22
 Identities = 72/251 (28%), Positives = 126/251 (50%), Gaps = 38/251 (15%)

Query: 7   SCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAY----ILLAMG 62
           +C+KY MF FNF  +L G  +LA+ IWV V      + +  +  + + +Y    IL+A+G
Sbjct: 6   ACIKYSMFTFNFLFWLCGILILALAIWVRVSNDS--QAIFGSEDVGSSSYVAVDILIAVG 63

Query: 63  GLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELT 122
            ++ +LGFLGCCGA++E++C+LL FF+ +L+I L +++  IL  +F+    R    + L 
Sbjct: 64  AIIMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDR-IVNETLY 122

Query: 123 KHYQGNNDTDIFSATWNSVMIT----FGCCG-VNGPEDFKFASVFRLLTLDSEEVPEACC 177
           ++ +  + T      +   +I     F CCG VNG  D+           + +  PE C 
Sbjct: 123 ENTKLLSATGESEKQFQEAIIVFQEEFKCCGLVNGAADW---------GNNFQHYPELCA 173

Query: 178 ----RREPQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIE 233
               +R  QS +G  + +E C+     FL K              + +   ++ G+  IE
Sbjct: 174 CLDKQRPCQSYNGKQVYKETCISFIKDFLAKN-------------LIIVIGISFGLAVIE 220

Query: 234 LFAMIFAMCLF 244
           +  ++F+M L+
Sbjct: 221 ILGLVFSMVLY 231


>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
          Length = 268

 Score =  103 bits (257), Expect = 1e-22
 Identities = 69/257 (26%), Positives = 121/257 (47%), Gaps = 24/257 (9%)

Query: 8   CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLL-LTGAYILLAMGGLLF 66
           C+KY +F FN   +  G   L IG+W   +      I +   L      ++ L +GG++F
Sbjct: 14  CIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMF 73

Query: 67  LLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTRE--FFTKELTKH 124
           +LGF GC GA+REN  LL FF +F+ IIF  EL+A +LAF+F++ +  +  FF     + 
Sbjct: 74  ILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFINNNIRA 133

Query: 125 YQGNND----TDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEE----VPEAC 176
           Y+ + D     D     W        CCG  G +D+     F     ++      VP +C
Sbjct: 134 YRDDIDLQNLIDFTQEYWQ-------CCGAFGADDWNLNIYFNCTDSNASRERCGVPFSC 186

Query: 177 CRREPQSRDGVLL-----SREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLA 231
           C ++P + D +       +R++  + + + +  +GC        +  + +   + IG+  
Sbjct: 187 CTKDP-AEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIAL 245

Query: 232 IELFAMIFAMCLFRGIQ 248
           +++F +  A  L   I+
Sbjct: 246 LQIFGICLAQNLVSDIE 262


>gi|91199546 CD63 antigen isoform B [Homo sapiens]
          Length = 236

 Score = 97.8 bits (242), Expect = 8e-21
 Identities = 65/245 (26%), Positives = 122/245 (49%), Gaps = 23/245 (9%)

Query: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLL 65
           + C+K+L++V           L+A+G+   +       I  A P  L    +++A+G  L
Sbjct: 7   MKCVKFLLYVLLLAFCACAVGLIAVGVGAQL-VLSQTIIQGATPGSLLPV-VIIAVGVFL 64

Query: 66  FLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFT--KELTK 123
           FL+ F+GCCGA +EN CL++ F +F+ +I L E++AAI  ++FR+ +  EF    ++  +
Sbjct: 65  FLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQME 124

Query: 124 HYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQS 183
           +Y  NN T   ++  + +   F CCG     D++     ++ ++    VP++CC      
Sbjct: 125 NYPKNNHT---ASILDRMQADFKCCGAANYTDWE-----KIPSMSKNRVPDSCCINVTVG 176

Query: 184 RDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCL 243
             G+  + +         ++K+GC   I       V +  A A+G+  +    ++FA CL
Sbjct: 177 -CGINFNEKA--------IHKEGCVEKIGGWLRKNVLVVAAAALGIAFV--LGIVFACCL 225

Query: 244 FRGIQ 248
            + I+
Sbjct: 226 VKSIR 230


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.334    0.148    0.468 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,726,477
Number of Sequences: 37866
Number of extensions: 358940
Number of successful extensions: 1523
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 1369
Number of HSP's gapped (non-prelim): 97
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.5 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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