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Search of human proteins with 42476111
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42476111 guanine nucleotide binding protein (G protein)
alpha 12 [Homo sapiens]
(381 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42476111 guanine nucleotide binding protein (G protein) alpha... 753 0.0
gi|24111250 guanine nucleotide binding protein (G protein), alph... 476 e-134
gi|40254462 guanine nucleotide binding protein (G protein), q po... 303 2e-82
gi|115511049 guanine nucleotide binding protein (G protein), alp... 299 3e-81
gi|4758444 G alpha 14 [Homo sapiens] 289 3e-78
gi|10567816 guanine nucleotide binding protein, alpha activating... 282 4e-76
gi|156139155 guanine nucleotide binding protein, alpha transduci... 280 2e-75
gi|162461738 guanine nucleotide binding protein, alpha activatin... 277 1e-74
gi|20330805 guanine nucleotide binding protein, alpha transducin... 274 8e-74
gi|33946324 guanine nucleotide binding protein (G protein), alph... 271 7e-73
gi|4504051 guanine nucleotide binding protein, alpha z polypepti... 271 9e-73
gi|156104883 guanine nucleotide binding protein (G protein), alp... 270 1e-72
gi|5729850 guanine nucleotide binding protein (G protein), alpha... 268 6e-72
gi|22027522 rod-type transducin alpha subunit [Homo sapiens] 264 1e-70
gi|22027520 rod-type transducin alpha subunit [Homo sapiens] 264 1e-70
gi|4504041 guanine nucleotide binding protein (G protein), alpha... 262 4e-70
gi|117938765 GNAS complex locus isoform g [Homo sapiens] 231 8e-61
gi|18426900 GNAS complex locus GNASS [Homo sapiens] 231 8e-61
gi|33695153 guanine nucleotide binding protein (G protein), alph... 228 5e-60
gi|4504047 GNAS complex locus GNASL [Homo sapiens] 227 1e-59
gi|117938762 GNAS complex locus isoform f [Homo sapiens] 227 2e-59
gi|117938759 GNAS complex locus XLas [Homo sapiens] 226 3e-59
gi|4504043 guanine nucleotide binding protein (G protein), alpha... 219 3e-57
gi|215272301 guanine nucleotide binding protein (G protein), alp... 219 3e-57
gi|4502211 ADP-ribosylation factor 6 [Homo sapiens] 42 0.001
gi|7705827 SAR1a gene homolog 2 [Homo sapiens] 40 0.003
gi|75709204 SAR1a gene homolog 2 [Homo sapiens] 40 0.003
gi|217416369 SAR1a gene homolog 1 [Homo sapiens] 40 0.003
gi|9910542 SAR1a gene homolog 1 [Homo sapiens] 40 0.003
gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam... 40 0.003
>gi|42476111 guanine nucleotide binding protein (G protein) alpha 12
[Homo sapiens]
Length = 381
Score = 753 bits (1943), Expect = 0.0
Identities = 381/381 (100%), Positives = 381/381 (100%)
Query: 1 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI 60
MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI
Sbjct: 1 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI 60
Query: 61 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ 120
LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ
Sbjct: 61 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ 120
Query: 121 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK 180
YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK
Sbjct: 121 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK 180
Query: 181 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ 240
YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ
Sbjct: 181 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ 240
Query: 241 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL 300
CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL
Sbjct: 241 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL 300
Query: 301 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR 360
LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR
Sbjct: 301 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR 360
Query: 361 FVFHAVKDTILQENLKDIMLQ 381
FVFHAVKDTILQENLKDIMLQ
Sbjct: 361 FVFHAVKDTILQENLKDIMLQ 381
>gi|24111250 guanine nucleotide binding protein (G protein), alpha
13 [Homo sapiens]
Length = 377
Score = 476 bits (1226), Expect = e-134
Identities = 236/354 (66%), Positives = 293/354 (82%), Gaps = 5/354 (1%)
Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
E E +R+S++ID L+RE+ V+RLVKILLLGAGESGKSTFLKQMRIIHG++FDQ+A E
Sbjct: 24 EAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREE 83
Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLP----VEPATFQ 148
FR TI+ N++KG RVLVDAR+KL IPW + N++HG +M+F+ +A + VE F
Sbjct: 84 FRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFL 143
Query: 149 LYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKAT 208
Y+PA+ ALW DSGI+ A+ RR EFQLGESVKYFLDNLD++G+ +Y PS+QDILLAR+ T
Sbjct: 144 QYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPT 203
Query: 209 KGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTN 268
KGI E+DF IK +PFKMVDVGGQRS+R++WF+CFD +TSILF+VSSSE+DQVLMEDR TN
Sbjct: 204 KGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTN 263
Query: 269 RLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQ 328
RL ES+NIFETIVNN++F NVSIILFLNK DLL EKV+ VSIK +F +F GDPH L DVQ
Sbjct: 264 RLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPHCLRDVQ 323
Query: 329 RYLVQCFDRKRRN-RSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ 381
++LV+CF KRR+ + KPL+HHFTTAI+TEN+R VF VKDTIL +NLK +MLQ
Sbjct: 324 KFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ 377
>gi|40254462 guanine nucleotide binding protein (G protein), q
polypeptide [Homo sapiens]
Length = 359
Score = 303 bits (776), Expect = 2e-82
Identities = 156/355 (43%), Positives = 223/355 (62%), Gaps = 20/355 (5%)
Query: 34 REARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEF 93
+EARR + +I+ L R++R RR +K+LLLG GESGKSTF+KQMRIIHG + + F
Sbjct: 16 KEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGF 75
Query: 94 RDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLM--------AFENKAGLPVEPA 145
++ NI + ++ A D L IP++Y N+ H + AFEN
Sbjct: 76 TKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENP-------- 127
Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
YV A+ +LW D GI+E + RR E+QL +S KY+L++LDR+ Y P++QD+L R
Sbjct: 128 ----YVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVR 183
Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
T GI+E+ F ++ + F+MVDVGGQRS+R+KW CF+ +TSI+F+V+ SEYDQVL+E
Sbjct: 184 VPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESD 243
Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLE 325
NR+ ES +F TI+ F N S+ILFLNK DLL EK+ + +FP++ G +
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQ 303
Query: 326 DVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380
+ ++++ F + K ++ HFT A DTEN+RFVF AVKDTILQ NLK+ L
Sbjct: 304 AAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL 358
>gi|115511049 guanine nucleotide binding protein (G protein), alpha
11 (Gq class) [Homo sapiens]
Length = 359
Score = 299 bits (765), Expect = 3e-81
Identities = 152/351 (43%), Positives = 227/351 (64%), Gaps = 6/351 (1%)
Query: 31 DAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKAL 90
D +E++R + +I+ L R++R RR +K+LLLG GESGKSTF+KQMRIIHG + ++
Sbjct: 13 DEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDK 72
Query: 91 LEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQ-L 149
F ++ NI + ++ A + L I ++Y +N+ + + + + + + TF+
Sbjct: 73 RGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVE-----KVTTFEHQ 127
Query: 150 YVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATK 209
YV A+ LW D GI+E + RR E+QL +S KY+L ++DRI L Y P++QD+L R T
Sbjct: 128 YVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVLRVRVPTT 187
Query: 210 GIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNR 269
GI+E+ F ++ I F+MVDVGGQRS+R+KW CF+ +TSI+F+V+ SEYDQVL+E NR
Sbjct: 188 GIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENR 247
Query: 270 LVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQR 329
+ ES +F TI+ F N S+ILFLNK DLL +K+ + +FP+F G + +
Sbjct: 248 MEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQRDAQAARE 307
Query: 330 YLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380
++++ F + K ++ HFT A DTEN+RFVF AVKDTILQ NLK+ L
Sbjct: 308 FILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL 358
>gi|4758444 G alpha 14 [Homo sapiens]
Length = 355
Score = 289 bits (739), Expect = 3e-78
Identities = 146/349 (41%), Positives = 225/349 (64%), Gaps = 6/349 (1%)
Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
E+E++R S +I+ L R+++ RR +K+LLLG GESGKSTF+KQMRIIHG + +
Sbjct: 11 EKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKG 70
Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFE-NKAGLPVEPATFQLYV 151
F ++ NI + ++ A D L I + +N+++ + E +K + + V
Sbjct: 71 FTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSM-----LSREQV 125
Query: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211
A+ LW+D GI+E + RR E+QL +S KY+L ++DRI ++ P++QD+L R T GI
Sbjct: 126 EAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGI 185
Query: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271
+E+ F ++ I F+MVDVGGQRS+R+KW CF+ +TSI+F+V+ SEYDQVL E NR+
Sbjct: 186 IEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRME 245
Query: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331
ES +F+TI+ F N S+ILFLNK DLL EK+ + +FP++ G + + ++
Sbjct: 246 ESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRAARDFI 305
Query: 332 VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380
++ + + ++ K ++ HFT A DT+N+RFVF AVKDTILQ NL++ L
Sbjct: 306 LKLYQDQNPDKEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNLREFNL 354
>gi|10567816 guanine nucleotide binding protein, alpha activating
polypeptide O isoform a [Homo sapiens]
Length = 354
Score = 282 bits (721), Expect = 4e-76
Identities = 152/345 (44%), Positives = 220/345 (63%), Gaps = 5/345 (1%)
Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
ER A RS+ I+ L + + + VK+LLLGAGESGKST +KQM+IIH F + + +
Sbjct: 9 ERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQ 68
Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLP-VEPATFQLYV 151
++ ++ N ++ +V A D LGI +Y + E+ M + + + EP + +L +
Sbjct: 69 YKPVVYSNTIQSLAAIVRAMDTLGI--EYGDKERKADAKMVCDVVSRMEDTEPFSAEL-L 125
Query: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211
A+ LW DSGI+E F+R E+QL +S KY+LD+LDRIG +Y P++QDIL R T GI
Sbjct: 126 SAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGI 185
Query: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271
VE F K + F++ DVGGQRS+R+KW CF+ +T+I+F V+ S YDQVL ED TNR+
Sbjct: 186 VETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMH 245
Query: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331
ES+ +F++I NNK F + SIILFLNK DL EK+K + FP++ G P+ ED Y+
Sbjct: 246 ESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTG-PNTYEDAAAYI 304
Query: 332 VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLK 376
F+ K R+ +K ++ H T A DT N++ VF AV D I+ NL+
Sbjct: 305 QAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLR 349
>gi|156139155 guanine nucleotide binding protein, alpha transducing
3 [Homo sapiens]
Length = 354
Score = 280 bits (716), Expect = 2e-75
Identities = 151/353 (42%), Positives = 214/353 (60%), Gaps = 5/353 (1%)
Query: 26 GSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF 85
GSG +E+ +RS++++ L + R VK+LLLGAGESGKST +KQM+IIH +
Sbjct: 2 GSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGY 61
Query: 86 DQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPA 145
++ +EF+ I+ N L+ +V A LGI + + + L A N L
Sbjct: 62 SEQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMANT--LEDGGM 119
Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
T QL + LWRD GI+ F R SE+QL +S Y+L++LDRI Y P++QD+L +R
Sbjct: 120 TPQL-AEVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSR 178
Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
T GI+E F K + F+M DVGGQRS+R+KW CF+G+T I+F + S YD VL+ED
Sbjct: 179 VKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDE 238
Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLE 325
NR+ ES+++F +I N+K F SI+LFLNK D+ EKV V + FP++ G P+ E
Sbjct: 239 EVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTKVHLSICFPEYTG-PNTFE 297
Query: 326 DVQRYLV-QCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
D Y+ Q D + K ++ H T A DT+NV+FVF AV D I++ENLKD
Sbjct: 298 DAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKD 350
>gi|162461738 guanine nucleotide binding protein, alpha activating
polypeptide O isoform b [Homo sapiens]
Length = 354
Score = 277 bits (708), Expect = 1e-74
Identities = 148/345 (42%), Positives = 219/345 (63%), Gaps = 5/345 (1%)
Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
ER A RS+ I+ L + + + VK+LLLGAGESGKST +KQM+IIH F + + +
Sbjct: 9 ERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQ 68
Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLP-VEPATFQLYV 151
++ ++ N ++ +V A D LGI +Y + E+ M + + + EP + +L +
Sbjct: 69 YKPVVYSNTIQSLAAIVRAMDTLGI--EYGDKERKADAKMVCDVVSRMEDTEPFSAEL-L 125
Query: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211
A+ LW DSGI+E F+R E+QL +S KY+LD+LDRIG +Y P++QDIL R T GI
Sbjct: 126 SAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGI 185
Query: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271
VE F K + F++ DVGGQRS+R+KW CF+ +T+I+F V+ S YDQVL ED TNR+
Sbjct: 186 VETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMH 245
Query: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331
ES+ +F++I NNK F + SIILFLNK D+ EK+K + FP++ G P + Y+
Sbjct: 246 ESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTG-PSAFTEAVAYI 304
Query: 332 VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLK 376
++ K ++ K ++ H T A DT N++FVF AV D I+ +NL+
Sbjct: 305 QAQYESKNKSAHKEIYTHVTCATDTNNIQFVFDAVTDVIIAKNLR 349
>gi|20330805 guanine nucleotide binding protein, alpha transducing
activity polypeptide 2 [Homo sapiens]
Length = 354
Score = 274 bits (701), Expect = 8e-74
Identities = 147/354 (41%), Positives = 214/354 (60%), Gaps = 7/354 (1%)
Query: 26 GSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF 85
GSGA ++E +RS++++ L + + VK+LLLGAGESGKST +KQM+IIH +
Sbjct: 2 GSGASAEDKELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGY 61
Query: 86 DQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPA 145
+ LEF+ I+ N+L+ ++ A LGI + G L N +E
Sbjct: 62 SPEECLEFKAIIYGNVLQSILAIIRAMTTLGIDYAEPSCADDGRQL----NNLADSIEEG 117
Query: 146 TFQL-YVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLA 204
T V + LW+D G++ F R +E+QL +S Y+L+ L+RI Y PS+QD+L +
Sbjct: 118 TMPPELVEVIRRLWKDGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLPSEQDVLRS 177
Query: 205 RKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMED 264
R T GI+E F +K + F+M DVGGQRS+R+KW CF+G+T I+F + S YD VL+ED
Sbjct: 178 RVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVED 237
Query: 265 RRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRL 324
NR+ ES+++F +I N+K F SI+LFLNK DL EK+K V + FP++ G+ +
Sbjct: 238 DEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGN-NSY 296
Query: 325 EDVQRYL-VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
+D Y+ Q D R K ++ H T A DT+NV+FVF AV D I++ENLKD
Sbjct: 297 DDAGNYIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKD 350
>gi|33946324 guanine nucleotide binding protein (G protein), alpha
inhibiting activity polypeptide 1 [Homo sapiens]
Length = 354
Score = 271 bits (693), Expect = 7e-73
Identities = 147/348 (42%), Positives = 218/348 (62%), Gaps = 9/348 (2%)
Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
++ A RS+ ID L + R VK+LLLGAGESGKST +KQM+IIH + ++ +
Sbjct: 9 DKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQ 68
Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSE--NEKHGMFLMAFENKAGLPVEPATFQLY 150
++ ++ N ++ ++ A +L I + S ++ +F++A + G T +L
Sbjct: 69 YKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGF----MTAEL- 123
Query: 151 VPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKG 210
+ LW+DSG++ F+R E+QL +S Y+L++LDRI Q NY P++QD+L R T G
Sbjct: 124 AGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTG 183
Query: 211 IVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRL 270
IVE F K + FKM DVGGQRS+R+KW CF+G+T+I+F V+ S+YD VL ED NR+
Sbjct: 184 IVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRM 243
Query: 271 VESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRY 330
ESM +F++I NNK F + SIILFLNK DL EK+K + +P++ G + E+ Y
Sbjct: 244 HESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGS-NTYEEAAAY 302
Query: 331 L-VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
+ Q D +R +K ++ HFT A DT+NV+FVF AV D I++ NLKD
Sbjct: 303 IQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKD 350
>gi|4504051 guanine nucleotide binding protein, alpha z polypeptide
[Homo sapiens]
Length = 355
Score = 271 bits (692), Expect = 9e-73
Identities = 149/349 (42%), Positives = 214/349 (61%), Gaps = 4/349 (1%)
Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
E+EA RRSR ID L E + RR +K+LLLG SGKST +KQM+IIH F+ +A E
Sbjct: 9 EKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKE 68
Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQLYVP 152
++ I N + ++ A L I + + + L A A E L V
Sbjct: 69 YKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGV- 127
Query: 153 ALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIV 212
+ LW D G + FSR SE+ L ++ Y+L++L+RI +Y P+ +DIL +R T GIV
Sbjct: 128 -MRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIV 186
Query: 213 EHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVE 272
E+ F K++ FKMVDVGGQRS+R+KW CF+G+T+I+F V S YD L ED +T+R+ E
Sbjct: 187 ENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAE 246
Query: 273 SMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLV 332
S+ +F++I NN F N S+ILFLNK DLL EK++ + + FP+++G + E+ Y+
Sbjct: 247 SLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQ-NTYEEAAVYIQ 305
Query: 333 QCFDRKRRNR-SKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380
+ F+ RN+ +K ++ HFT A DT N++FVF AV D I+Q NLK I L
Sbjct: 306 RQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGL 354
>gi|156104883 guanine nucleotide binding protein (G protein), alpha
15 (Gq class) [Homo sapiens]
Length = 374
Score = 270 bits (691), Expect = 1e-72
Identities = 141/361 (39%), Positives = 223/361 (61%), Gaps = 18/361 (4%)
Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
E+ A R ++I+ +L +++ R +K+LLLG GESGKSTF+KQMRIIHG + ++
Sbjct: 18 EKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKG 77
Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQL-YV 151
FR ++ NI R +++A ++L IP+ E++ H +M+ + P + TF+ Y
Sbjct: 78 FRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD-----PYKVTTFEKRYA 132
Query: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211
A+ LWRD+GIR + RR EF L +S Y+L +L+RI + Y P+ QD+L +R T GI
Sbjct: 133 AAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGI 192
Query: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271
E+ F ++K ++VDVGGQ+S+R+KW CF+ + +++++ S SEYDQ L E+ + NR+
Sbjct: 193 NEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMK 252
Query: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331
ES+ +F TI+ F + S+ILFLNK D+L EK+ T + +FP F+G E +R++
Sbjct: 253 ESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFI 312
Query: 332 VQCFDR------------KRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIM 379
+ + R K+ RS+ LF H+T A DT+N+R VF V+D++L L +I
Sbjct: 313 LDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEIN 372
Query: 380 L 380
L
Sbjct: 373 L 373
>gi|5729850 guanine nucleotide binding protein (G protein), alpha
inhibiting activity polypeptide 3 [Homo sapiens]
Length = 354
Score = 268 bits (685), Expect = 6e-72
Identities = 145/346 (41%), Positives = 207/346 (59%), Gaps = 5/346 (1%)
Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
++ A RS+ ID L + + VK+LLLGAGESGKST +KQM+IIH + + +
Sbjct: 9 DKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQ 68
Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQLYVP 152
++ ++ N ++ ++ A +L I + + L AG E
Sbjct: 69 YKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVL---AGSAEEGVMTPELAG 125
Query: 153 ALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIV 212
+ LWRD G++ FSR E+QL +S Y+L++LDRI Q NY P++QD+L R T GIV
Sbjct: 126 VIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIV 185
Query: 213 EHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVE 272
E F K + FKM DVGGQRS+R+KW CF+G+T+I+F V+ S+YD VL ED NR+ E
Sbjct: 186 ETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHE 245
Query: 273 SMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL- 331
SM +F++I NNK F SIILFLNK DL EK+K + +P++ G + E+ Y+
Sbjct: 246 SMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGS-NTYEEAAAYIQ 304
Query: 332 VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
Q D RR +K ++ HFT A DT+NV+FVF AV D I++ NLK+
Sbjct: 305 CQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKE 350
>gi|22027522 rod-type transducin alpha subunit [Homo sapiens]
Length = 350
Score = 264 bits (674), Expect = 1e-70
Identities = 146/353 (41%), Positives = 208/353 (58%), Gaps = 9/353 (2%)
Query: 26 GSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF 85
G+GA E+ SR+++ L + R VK+LLLGAGESGKST +KQM+IIH +
Sbjct: 2 GAGASAEEKH----SRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGY 57
Query: 86 DQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPA 145
+ LEF I+ N L+ +V A L I + S + LM + P
Sbjct: 58 SLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPK 117
Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
+ LW+DSGI+ F R SE+QL +S Y+L +L+R+ Y P++QD+L +R
Sbjct: 118 EMS---DIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSR 174
Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
T GI+E F K + F+M DVGGQRS+R+KW CF+G+T I+F+ + S YD VL+ED
Sbjct: 175 VKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDD 234
Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLE 325
NR+ ES+++F +I N++ F SI+LFLNK D+ EK+K + FPD+ G P+ E
Sbjct: 235 EVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKIKKAHLSICFPDYDG-PNTYE 293
Query: 326 DVQRYL-VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
D Y+ VQ + R K ++ H T A DT+NV+FVF AV D I++ENLKD
Sbjct: 294 DAGNYIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKD 346
>gi|22027520 rod-type transducin alpha subunit [Homo sapiens]
Length = 350
Score = 264 bits (674), Expect = 1e-70
Identities = 146/353 (41%), Positives = 208/353 (58%), Gaps = 9/353 (2%)
Query: 26 GSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF 85
G+GA E+ SR+++ L + R VK+LLLGAGESGKST +KQM+IIH +
Sbjct: 2 GAGASAEEKH----SRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGY 57
Query: 86 DQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPA 145
+ LEF I+ N L+ +V A L I + S + LM + P
Sbjct: 58 SLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPK 117
Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
+ LW+DSGI+ F R SE+QL +S Y+L +L+R+ Y P++QD+L +R
Sbjct: 118 EMS---DIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSR 174
Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
T GI+E F K + F+M DVGGQRS+R+KW CF+G+T I+F+ + S YD VL+ED
Sbjct: 175 VKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDD 234
Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLE 325
NR+ ES+++F +I N++ F SI+LFLNK D+ EK+K + FPD+ G P+ E
Sbjct: 235 EVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKIKKAHLSICFPDYDG-PNTYE 293
Query: 326 DVQRYL-VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
D Y+ VQ + R K ++ H T A DT+NV+FVF AV D I++ENLKD
Sbjct: 294 DAGNYIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKD 346
>gi|4504041 guanine nucleotide binding protein (G protein), alpha
inhibiting activity polypeptide 2 [Homo sapiens]
Length = 355
Score = 262 bits (669), Expect = 4e-70
Identities = 144/350 (41%), Positives = 208/350 (59%), Gaps = 12/350 (3%)
Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
++ A RS+ ID L + R VK+LLLGAGESGKST +KQM+IIH + ++ +
Sbjct: 9 DKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQ 68
Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAF----ENKAGLPVEPATFQ 148
+R ++ N ++ +V A L I + L A E + LP + +
Sbjct: 69 YRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSG-- 126
Query: 149 LYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKAT 208
+ LW D G++ F R E+QL +S Y+L++L+RI Q +Y P++QD+L R T
Sbjct: 127 ----VIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKT 182
Query: 209 KGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTN 268
GIVE F K + FKM DVGGQRS+R+KW CF+G+T+I+F V+ S YD VL ED N
Sbjct: 183 TGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMN 242
Query: 269 RLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQ 328
R+ ESM +F++I NNK F + SIILFLNK DL EK+ + FP++ G ++ ++
Sbjct: 243 RMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTG-ANKYDEAA 301
Query: 329 RYLVQCF-DRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
Y+ F D +R +K ++ HFT A DT+NV+FVF AV D I++ NLKD
Sbjct: 302 SYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKD 351
>gi|117938765 GNAS complex locus isoform g [Homo sapiens]
Length = 379
Score = 231 bits (589), Expect = 8e-61
Identities = 137/370 (37%), Positives = 207/370 (55%), Gaps = 23/370 (6%)
Query: 30 RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKA 89
R+ E+ R ++ I+ L ++++ R ++LLLGAGESGKST +KQMRI+H F+
Sbjct: 13 RNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDE 72
Query: 90 LLEFRDTIFDNILKGSRVLVDARDKLGIPWQYS--ENEKHGMFLMAFENKAGLPVEPATF 147
I +N+ + +V A L P + + EN+ ++++ N P +
Sbjct: 73 KATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFY 132
Query: 148 QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKA 207
+ ALW D G+R + R +E+QL + +YFLD +D I Q +Y PS QD+L R
Sbjct: 133 E----HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVL 188
Query: 208 TKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRT 267
T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+F+V+SS Y+ V+ ED +T
Sbjct: 189 TSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQT 248
Query: 268 NRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFR------- 318
NRL E++N+F++I NN+ +S+ILFLNK DLL EKV I+ +FP+F
Sbjct: 249 NRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPED 308
Query: 319 GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTENVRFVFHAVKDTI 370
P ED + + F R R + HFT A+DTEN+R VF+ +D I
Sbjct: 309 ATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDII 368
Query: 371 LQENLKDIML 380
+ +L+ L
Sbjct: 369 QRMHLRQYEL 378
>gi|18426900 GNAS complex locus GNASS [Homo sapiens]
Length = 380
Score = 231 bits (589), Expect = 8e-61
Identities = 139/372 (37%), Positives = 211/372 (56%), Gaps = 26/372 (6%)
Query: 30 RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF--DQ 87
R+ E+ R ++ I+ L ++++ R ++LLLGAGESGKST +KQMRI+H F D
Sbjct: 13 RNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDS 72
Query: 88 KALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYS--ENEKHGMFLMAFENKAGLPVEPA 145
+ + +D I +N+ + +V A L P + + EN+ ++++ N P
Sbjct: 73 EKATKVQD-IKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPE 131
Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
++ ALW D G+R + R +E+QL + +YFLD +D I Q +Y PS QD+L R
Sbjct: 132 FYE----HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCR 187
Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+F+V+SS Y+ V+ ED
Sbjct: 188 VLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDN 247
Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFR----- 318
+TNRL E++N+F++I NN+ +S+ILFLNK DLL EKV I+ +FP+F
Sbjct: 248 QTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTP 307
Query: 319 --GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTENVRFVFHAVKD 368
P ED + + F R R + HFT A+DTEN+R VF+ +D
Sbjct: 308 EDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRD 367
Query: 369 TILQENLKDIML 380
I + +L+ L
Sbjct: 368 IIQRMHLRQYEL 379
>gi|33695153 guanine nucleotide binding protein (G protein), alpha
activating activity polypeptide, olfactory type isoform
1 [Homo sapiens]
Length = 458
Score = 228 bits (582), Expect = 5e-60
Identities = 139/383 (36%), Positives = 217/383 (56%), Gaps = 33/383 (8%)
Query: 22 ERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIH 81
E R + R+A +EAR+ SR ID +L ++R +++ ++LLLGAGESGKST +KQMRI+H
Sbjct: 84 EEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILH 143
Query: 82 GREFD----QKALLEFRDTIFDNILKGSRVLVDARDKL--GIPWQYSENEKHGMFLMAFE 135
F+ ++ +L+ R + D I+ +V A + +P EN+ ++
Sbjct: 144 VNGFNPEEKKQKILDIRKNVKDAIV----TIVSAMSTIIPPVPLANPENQFRSDYI---- 195
Query: 136 NKAGLPVEPATF-QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNY 194
K+ P+ + Q + + LW D G++ F R +E+QL + +YFL+ +D + ++Y
Sbjct: 196 -KSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDY 254
Query: 195 FPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSS 254
P+ QD+L R T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+++ +
Sbjct: 255 TPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAAC 314
Query: 255 SEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKK 312
S Y+ V+ ED TNRL ES+++FE+I NN+ +SIILFLNK D+L EKV I+
Sbjct: 315 SSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIED 374
Query: 313 HFPDFR-------GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTE 357
+FP++ P ED + + F R R + HFT A+DTE
Sbjct: 375 YFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTE 434
Query: 358 NVRFVFHAVKDTILQENLKDIML 380
N+R VF+ +D I + +LK L
Sbjct: 435 NIRRVFNDCRDIIQRMHLKQYEL 457
>gi|4504047 GNAS complex locus GNASL [Homo sapiens]
Length = 394
Score = 227 bits (579), Expect = 1e-59
Identities = 141/385 (36%), Positives = 211/385 (54%), Gaps = 38/385 (9%)
Query: 30 RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIH-------G 82
R+ E+ R ++ I+ L ++++ R ++LLLGAGESGKST +KQMRI+H G
Sbjct: 13 RNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEG 72
Query: 83 REFDQKALLEFRD--------TIFDNILKGSRVLVDARDKLGIPWQYS--ENEKHGMFLM 132
E D +A D I +N+ + +V A L P + + EN+ +++
Sbjct: 73 GEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYIL 132
Query: 133 AFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQL 192
+ N P ++ ALW D G+R + R +E+QL + +YFLD +D I Q
Sbjct: 133 SVMNVPDFDFPPEFYE----HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQA 188
Query: 193 NYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMV 252
+Y PS QD+L R T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+F+V
Sbjct: 189 DYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVV 248
Query: 253 SSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSI 310
+SS Y+ V+ ED +TNRL E++N+F++I NN+ +S+ILFLNK DLL EKV I
Sbjct: 249 ASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKI 308
Query: 311 KKHFPDFR-------GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAID 355
+ +FP+F P ED + + F R R + HFT A+D
Sbjct: 309 EDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVD 368
Query: 356 TENVRFVFHAVKDTILQENLKDIML 380
TEN+R VF+ +D I + +L+ L
Sbjct: 369 TENIRRVFNDCRDIIQRMHLRQYEL 393
>gi|117938762 GNAS complex locus isoform f [Homo sapiens]
Length = 395
Score = 227 bits (578), Expect = 2e-59
Identities = 141/386 (36%), Positives = 211/386 (54%), Gaps = 39/386 (10%)
Query: 30 RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIH-------G 82
R+ E+ R ++ I+ L ++++ R ++LLLGAGESGKST +KQMRI+H G
Sbjct: 13 RNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEG 72
Query: 83 REFDQKALLEFRD---------TIFDNILKGSRVLVDARDKLGIPWQYS--ENEKHGMFL 131
E D +A D I +N+ + +V A L P + + EN+ ++
Sbjct: 73 GEEDPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYI 132
Query: 132 MAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQ 191
++ N P ++ ALW D G+R + R +E+QL + +YFLD +D I Q
Sbjct: 133 LSVMNVPDFDFPPEFYE----HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQ 188
Query: 192 LNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFM 251
+Y PS QD+L R T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+F+
Sbjct: 189 ADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFV 248
Query: 252 VSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VS 309
V+SS Y+ V+ ED +TNRL E++N+F++I NN+ +S+ILFLNK DLL EKV
Sbjct: 249 VASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSK 308
Query: 310 IKKHFPDFR-------GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAI 354
I+ +FP+F P ED + + F R R + HFT A+
Sbjct: 309 IEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAV 368
Query: 355 DTENVRFVFHAVKDTILQENLKDIML 380
DTEN+R VF+ +D I + +L+ L
Sbjct: 369 DTENIRRVFNDCRDIIQRMHLRQYEL 394
>gi|117938759 GNAS complex locus XLas [Homo sapiens]
Length = 1037
Score = 226 bits (575), Expect = 3e-59
Identities = 147/409 (35%), Positives = 217/409 (53%), Gaps = 38/409 (9%)
Query: 6 RTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGA 65
R+L +P + R+ R +R ++RS+ ID L E+ ++LLLGA
Sbjct: 632 RSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGA 691
Query: 66 GESGKSTFLKQMRIIH-------GREFDQKALLEFRD--------TIFDNILKGSRVLVD 110
GESGKST +KQMRI+H G E D +A D I +N+ + +V
Sbjct: 692 GESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVA 751
Query: 111 ARDKLGIPWQYS--ENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFS 168
A L P + + EN+ ++++ N P ++ ALW D G+R +
Sbjct: 752 AMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYE----HAKALWEDEGVRACYE 807
Query: 169 RRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDV 228
R +E+QL + +YFLD +D I Q +Y PS QD+L R T GI E F + K+ F M DV
Sbjct: 808 RSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDV 867
Query: 229 GGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFN 288
GGQR +R+KW QCF+ +T+I+F+V+SS Y+ V+ ED +TNRL E++N+F++I NN+
Sbjct: 868 GGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRT 927
Query: 289 VSIILFLNKMDLLVEKVKT--VSIKKHFPDFR-------GDPHRLEDVQRYLVQCFDRKR 339
+S+ILFLNK DLL EKV I+ +FP+F P ED + + F R
Sbjct: 928 ISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDE 987
Query: 340 RNRSKP--------LFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380
R + HFT A+DTEN+R VF+ +D I + +L+ L
Sbjct: 988 FLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYEL 1036
>gi|4504043 guanine nucleotide binding protein (G protein), alpha
activating activity polypeptide, olfactory type isoform
2 [Homo sapiens]
Length = 381
Score = 219 bits (558), Expect = 3e-57
Identities = 134/372 (36%), Positives = 208/372 (55%), Gaps = 33/372 (8%)
Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFD----QK 88
E+E R ++ I+ L +ER A + ++LLLGAGESGKST +KQMRI+H F+ ++
Sbjct: 18 EKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQ 77
Query: 89 ALLEFRDTIFDNILKGSRVLVDARDKL--GIPWQYSENEKHGMFLMAFENKAGLPVEPAT 146
+L+ R + D I+ +V A + +P EN+ ++ K+ P+
Sbjct: 78 KILDIRKNVKDAIV----TIVSAMSTIIPPVPLANPENQFRSDYI-----KSIAPITDFE 128
Query: 147 F-QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
+ Q + + LW D G++ F R +E+QL + +YFL+ +D + ++Y P+ QD+L R
Sbjct: 129 YSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCR 188
Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+++ + S Y+ V+ ED
Sbjct: 189 VLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDN 248
Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFR----- 318
TNRL ES+++FE+I NN+ +SIILFLNK D+L EKV I+ +FP++
Sbjct: 249 NTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVP 308
Query: 319 --GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTENVRFVFHAVKD 368
P ED + + F R R + HFT A+DTEN+R VF+ +D
Sbjct: 309 EDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRD 368
Query: 369 TILQENLKDIML 380
I + +LK L
Sbjct: 369 IIQRMHLKQYEL 380
>gi|215272301 guanine nucleotide binding protein (G protein), alpha
activating activity polypeptide, olfactory type isoform
2 [Homo sapiens]
Length = 381
Score = 219 bits (558), Expect = 3e-57
Identities = 134/372 (36%), Positives = 208/372 (55%), Gaps = 33/372 (8%)
Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFD----QK 88
E+E R ++ I+ L +ER A + ++LLLGAGESGKST +KQMRI+H F+ ++
Sbjct: 18 EKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQ 77
Query: 89 ALLEFRDTIFDNILKGSRVLVDARDKL--GIPWQYSENEKHGMFLMAFENKAGLPVEPAT 146
+L+ R + D I+ +V A + +P EN+ ++ K+ P+
Sbjct: 78 KILDIRKNVKDAIV----TIVSAMSTIIPPVPLANPENQFRSDYI-----KSIAPITDFE 128
Query: 147 F-QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
+ Q + + LW D G++ F R +E+QL + +YFL+ +D + ++Y P+ QD+L R
Sbjct: 129 YSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCR 188
Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+++ + S Y+ V+ ED
Sbjct: 189 VLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDN 248
Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFR----- 318
TNRL ES+++FE+I NN+ +SIILFLNK D+L EKV I+ +FP++
Sbjct: 249 NTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVP 308
Query: 319 --GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTENVRFVFHAVKD 368
P ED + + F R R + HFT A+DTEN+R VF+ +D
Sbjct: 309 EDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRD 368
Query: 369 TILQENLKDIML 380
I + +LK L
Sbjct: 369 IIQRMHLKQYEL 380
>gi|4502211 ADP-ribosylation factor 6 [Homo sapiens]
Length = 175
Score = 41.6 bits (96), Expect = 0.001
Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 10/93 (10%)
Query: 208 TKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRT 267
T G K + F + DVGGQ R W + G ++F+V ++ D
Sbjct: 44 TVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD--------- 94
Query: 268 NRLVESMNIFETIVNNKLFFNVSIILFLNKMDL 300
R+ E+ I+N++ + I++F NK DL
Sbjct: 95 -RIDEARQELHRIINDREMRDAIILIFANKQDL 126
>gi|7705827 SAR1a gene homolog 2 [Homo sapiens]
Length = 198
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/124 (25%), Positives = 54/124 (43%), Gaps = 12/124 (9%)
Query: 176 GESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQR 235
G+ V LDN + L+ K D L T + I + F D+GG R
Sbjct: 26 GKLVFLGLDNAGKTTLLHML--KDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQAR 83
Query: 236 QKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFL 295
+ W I I+F+V ++++ RL+ES ++++ ++ NV I++
Sbjct: 84 RVWKNYLPAINGIVFLVDCADHE----------RLLESKEELDSLMTDETIANVPILILG 133
Query: 296 NKMD 299
NK+D
Sbjct: 134 NKID 137
>gi|75709204 SAR1a gene homolog 2 [Homo sapiens]
Length = 198
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/124 (25%), Positives = 54/124 (43%), Gaps = 12/124 (9%)
Query: 176 GESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQR 235
G+ V LDN + L+ K D L T + I + F D+GG R
Sbjct: 26 GKLVFLGLDNAGKTTLLHML--KDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQAR 83
Query: 236 QKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFL 295
+ W I I+F+V ++++ RL+ES ++++ ++ NV I++
Sbjct: 84 RVWKNYLPAINGIVFLVDCADHE----------RLLESKEELDSLMTDETIANVPILILG 133
Query: 296 NKMD 299
NK+D
Sbjct: 134 NKID 137
>gi|217416369 SAR1a gene homolog 1 [Homo sapiens]
Length = 198
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 12/124 (9%)
Query: 176 GESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQR 235
G+ V LDN + L+ K D L T + I + F D+GG R
Sbjct: 26 GKLVFLGLDNAGKTTLLHML--KDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQAR 83
Query: 236 QKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFL 295
+ W I I+F+V +++ +RLVES ++ ++ NV I++
Sbjct: 84 RVWKNYLPAINGIVFLVDCADH----------SRLVESKVELNALMTDETISNVPILILG 133
Query: 296 NKMD 299
NK+D
Sbjct: 134 NKID 137
>gi|9910542 SAR1a gene homolog 1 [Homo sapiens]
Length = 198
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 12/124 (9%)
Query: 176 GESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQR 235
G+ V LDN + L+ K D L T + I + F D+GG R
Sbjct: 26 GKLVFLGLDNAGKTTLLHML--KDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQAR 83
Query: 236 QKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFL 295
+ W I I+F+V +++ +RLVES ++ ++ NV I++
Sbjct: 84 RVWKNYLPAINGIVFLVDCADH----------SRLVESKVELNALMTDETISNVPILILG 133
Query: 296 NKMD 299
NK+D
Sbjct: 134 NKID 137
>gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma
[Homo sapiens]
Length = 546
Score = 40.0 bits (92), Expect = 0.003
Identities = 33/144 (22%), Positives = 60/144 (41%), Gaps = 13/144 (9%)
Query: 160 DSGIREAFSRRSEFQLGES--VKYFLDNLDRIGQLNY-FPSKQDILLARKATKGIVEHDF 216
D+ I F++ + +G ++ LD G+ F KQD + T G
Sbjct: 384 DASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETV 443
Query: 217 VIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNI 276
K + F + DVGG+ R W + +++F+V SS D R+ E+ +
Sbjct: 444 EYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRD----------RISEAHSE 493
Query: 277 FETIVNNKLFFNVSIILFLNKMDL 300
++ K + +++F NK D+
Sbjct: 494 LAKLLTEKELRDALLLIFANKQDV 517
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.140 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,303,583
Number of Sequences: 37866
Number of extensions: 503874
Number of successful extensions: 2168
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2061
Number of HSP's gapped (non-prelim): 90
length of query: 381
length of database: 18,247,518
effective HSP length: 104
effective length of query: 277
effective length of database: 14,309,454
effective search space: 3963718758
effective search space used: 3963718758
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.