BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|42476111 guanine nucleotide binding protein (G protein) alpha 12 [Homo sapiens] (381 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|42476111 guanine nucleotide binding protein (G protein) alpha... 753 0.0 gi|24111250 guanine nucleotide binding protein (G protein), alph... 476 e-134 gi|40254462 guanine nucleotide binding protein (G protein), q po... 303 2e-82 gi|115511049 guanine nucleotide binding protein (G protein), alp... 299 3e-81 gi|4758444 G alpha 14 [Homo sapiens] 289 3e-78 gi|10567816 guanine nucleotide binding protein, alpha activating... 282 4e-76 gi|156139155 guanine nucleotide binding protein, alpha transduci... 280 2e-75 gi|162461738 guanine nucleotide binding protein, alpha activatin... 277 1e-74 gi|20330805 guanine nucleotide binding protein, alpha transducin... 274 8e-74 gi|33946324 guanine nucleotide binding protein (G protein), alph... 271 7e-73 gi|4504051 guanine nucleotide binding protein, alpha z polypepti... 271 9e-73 gi|156104883 guanine nucleotide binding protein (G protein), alp... 270 1e-72 gi|5729850 guanine nucleotide binding protein (G protein), alpha... 268 6e-72 gi|22027522 rod-type transducin alpha subunit [Homo sapiens] 264 1e-70 gi|22027520 rod-type transducin alpha subunit [Homo sapiens] 264 1e-70 gi|4504041 guanine nucleotide binding protein (G protein), alpha... 262 4e-70 gi|117938765 GNAS complex locus isoform g [Homo sapiens] 231 8e-61 gi|18426900 GNAS complex locus GNASS [Homo sapiens] 231 8e-61 gi|33695153 guanine nucleotide binding protein (G protein), alph... 228 5e-60 gi|4504047 GNAS complex locus GNASL [Homo sapiens] 227 1e-59 gi|117938762 GNAS complex locus isoform f [Homo sapiens] 227 2e-59 gi|117938759 GNAS complex locus XLas [Homo sapiens] 226 3e-59 gi|4504043 guanine nucleotide binding protein (G protein), alpha... 219 3e-57 gi|215272301 guanine nucleotide binding protein (G protein), alp... 219 3e-57 gi|4502211 ADP-ribosylation factor 6 [Homo sapiens] 42 0.001 gi|7705827 SAR1a gene homolog 2 [Homo sapiens] 40 0.003 gi|75709204 SAR1a gene homolog 2 [Homo sapiens] 40 0.003 gi|217416369 SAR1a gene homolog 1 [Homo sapiens] 40 0.003 gi|9910542 SAR1a gene homolog 1 [Homo sapiens] 40 0.003 gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam... 40 0.003 >gi|42476111 guanine nucleotide binding protein (G protein) alpha 12 [Homo sapiens] Length = 381 Score = 753 bits (1943), Expect = 0.0 Identities = 381/381 (100%), Positives = 381/381 (100%) Query: 1 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI 60 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI Sbjct: 1 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI 60 Query: 61 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ 120 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ Sbjct: 61 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ 120 Query: 121 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK 180 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK Sbjct: 121 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK 180 Query: 181 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ 240 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ Sbjct: 181 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ 240 Query: 241 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL 300 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL Sbjct: 241 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL 300 Query: 301 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR 360 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR Sbjct: 301 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR 360 Query: 361 FVFHAVKDTILQENLKDIMLQ 381 FVFHAVKDTILQENLKDIMLQ Sbjct: 361 FVFHAVKDTILQENLKDIMLQ 381 >gi|24111250 guanine nucleotide binding protein (G protein), alpha 13 [Homo sapiens] Length = 377 Score = 476 bits (1226), Expect = e-134 Identities = 236/354 (66%), Positives = 293/354 (82%), Gaps = 5/354 (1%) Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92 E E +R+S++ID L+RE+ V+RLVKILLLGAGESGKSTFLKQMRIIHG++FDQ+A E Sbjct: 24 EAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREE 83 Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLP----VEPATFQ 148 FR TI+ N++KG RVLVDAR+KL IPW + N++HG +M+F+ +A + VE F Sbjct: 84 FRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFL 143 Query: 149 LYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKAT 208 Y+PA+ ALW DSGI+ A+ RR EFQLGESVKYFLDNLD++G+ +Y PS+QDILLAR+ T Sbjct: 144 QYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPT 203 Query: 209 KGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTN 268 KGI E+DF IK +PFKMVDVGGQRS+R++WF+CFD +TSILF+VSSSE+DQVLMEDR TN Sbjct: 204 KGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTN 263 Query: 269 RLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQ 328 RL ES+NIFETIVNN++F NVSIILFLNK DLL EKV+ VSIK +F +F GDPH L DVQ Sbjct: 264 RLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPHCLRDVQ 323 Query: 329 RYLVQCFDRKRRN-RSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ 381 ++LV+CF KRR+ + KPL+HHFTTAI+TEN+R VF VKDTIL +NLK +MLQ Sbjct: 324 KFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ 377 >gi|40254462 guanine nucleotide binding protein (G protein), q polypeptide [Homo sapiens] Length = 359 Score = 303 bits (776), Expect = 2e-82 Identities = 156/355 (43%), Positives = 223/355 (62%), Gaps = 20/355 (5%) Query: 34 REARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEF 93 +EARR + +I+ L R++R RR +K+LLLG GESGKSTF+KQMRIIHG + + F Sbjct: 16 KEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGF 75 Query: 94 RDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLM--------AFENKAGLPVEPA 145 ++ NI + ++ A D L IP++Y N+ H + AFEN Sbjct: 76 TKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENP-------- 127 Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205 YV A+ +LW D GI+E + RR E+QL +S KY+L++LDR+ Y P++QD+L R Sbjct: 128 ----YVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVR 183 Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265 T GI+E+ F ++ + F+MVDVGGQRS+R+KW CF+ +TSI+F+V+ SEYDQVL+E Sbjct: 184 VPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESD 243 Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLE 325 NR+ ES +F TI+ F N S+ILFLNK DLL EK+ + +FP++ G + Sbjct: 244 NENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQ 303 Query: 326 DVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380 + ++++ F + K ++ HFT A DTEN+RFVF AVKDTILQ NLK+ L Sbjct: 304 AAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL 358 >gi|115511049 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) [Homo sapiens] Length = 359 Score = 299 bits (765), Expect = 3e-81 Identities = 152/351 (43%), Positives = 227/351 (64%), Gaps = 6/351 (1%) Query: 31 DAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKAL 90 D +E++R + +I+ L R++R RR +K+LLLG GESGKSTF+KQMRIIHG + ++ Sbjct: 13 DEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDK 72 Query: 91 LEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQ-L 149 F ++ NI + ++ A + L I ++Y +N+ + + + + + + TF+ Sbjct: 73 RGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVE-----KVTTFEHQ 127 Query: 150 YVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATK 209 YV A+ LW D GI+E + RR E+QL +S KY+L ++DRI L Y P++QD+L R T Sbjct: 128 YVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVLRVRVPTT 187 Query: 210 GIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNR 269 GI+E+ F ++ I F+MVDVGGQRS+R+KW CF+ +TSI+F+V+ SEYDQVL+E NR Sbjct: 188 GIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENR 247 Query: 270 LVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQR 329 + ES +F TI+ F N S+ILFLNK DLL +K+ + +FP+F G + + Sbjct: 248 MEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQRDAQAARE 307 Query: 330 YLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380 ++++ F + K ++ HFT A DTEN+RFVF AVKDTILQ NLK+ L Sbjct: 308 FILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL 358 >gi|4758444 G alpha 14 [Homo sapiens] Length = 355 Score = 289 bits (739), Expect = 3e-78 Identities = 146/349 (41%), Positives = 225/349 (64%), Gaps = 6/349 (1%) Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92 E+E++R S +I+ L R+++ RR +K+LLLG GESGKSTF+KQMRIIHG + + Sbjct: 11 EKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKG 70 Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFE-NKAGLPVEPATFQLYV 151 F ++ NI + ++ A D L I + +N+++ + E +K + + V Sbjct: 71 FTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSM-----LSREQV 125 Query: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211 A+ LW+D GI+E + RR E+QL +S KY+L ++DRI ++ P++QD+L R T GI Sbjct: 126 EAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGI 185 Query: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271 +E+ F ++ I F+MVDVGGQRS+R+KW CF+ +TSI+F+V+ SEYDQVL E NR+ Sbjct: 186 IEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRME 245 Query: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331 ES +F+TI+ F N S+ILFLNK DLL EK+ + +FP++ G + + ++ Sbjct: 246 ESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRAARDFI 305 Query: 332 VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380 ++ + + ++ K ++ HFT A DT+N+RFVF AVKDTILQ NL++ L Sbjct: 306 LKLYQDQNPDKEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNLREFNL 354 >gi|10567816 guanine nucleotide binding protein, alpha activating polypeptide O isoform a [Homo sapiens] Length = 354 Score = 282 bits (721), Expect = 4e-76 Identities = 152/345 (44%), Positives = 220/345 (63%), Gaps = 5/345 (1%) Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92 ER A RS+ I+ L + + + VK+LLLGAGESGKST +KQM+IIH F + + + Sbjct: 9 ERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQ 68 Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLP-VEPATFQLYV 151 ++ ++ N ++ +V A D LGI +Y + E+ M + + + EP + +L + Sbjct: 69 YKPVVYSNTIQSLAAIVRAMDTLGI--EYGDKERKADAKMVCDVVSRMEDTEPFSAEL-L 125 Query: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211 A+ LW DSGI+E F+R E+QL +S KY+LD+LDRIG +Y P++QDIL R T GI Sbjct: 126 SAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGI 185 Query: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271 VE F K + F++ DVGGQRS+R+KW CF+ +T+I+F V+ S YDQVL ED TNR+ Sbjct: 186 VETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMH 245 Query: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331 ES+ +F++I NNK F + SIILFLNK DL EK+K + FP++ G P+ ED Y+ Sbjct: 246 ESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTG-PNTYEDAAAYI 304 Query: 332 VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLK 376 F+ K R+ +K ++ H T A DT N++ VF AV D I+ NL+ Sbjct: 305 QAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLR 349 >gi|156139155 guanine nucleotide binding protein, alpha transducing 3 [Homo sapiens] Length = 354 Score = 280 bits (716), Expect = 2e-75 Identities = 151/353 (42%), Positives = 214/353 (60%), Gaps = 5/353 (1%) Query: 26 GSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF 85 GSG +E+ +RS++++ L + R VK+LLLGAGESGKST +KQM+IIH + Sbjct: 2 GSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGY 61 Query: 86 DQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPA 145 ++ +EF+ I+ N L+ +V A LGI + + + L A N L Sbjct: 62 SEQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMANT--LEDGGM 119 Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205 T QL + LWRD GI+ F R SE+QL +S Y+L++LDRI Y P++QD+L +R Sbjct: 120 TPQL-AEVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSR 178 Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265 T GI+E F K + F+M DVGGQRS+R+KW CF+G+T I+F + S YD VL+ED Sbjct: 179 VKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDE 238 Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLE 325 NR+ ES+++F +I N+K F SI+LFLNK D+ EKV V + FP++ G P+ E Sbjct: 239 EVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTKVHLSICFPEYTG-PNTFE 297 Query: 326 DVQRYLV-QCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377 D Y+ Q D + K ++ H T A DT+NV+FVF AV D I++ENLKD Sbjct: 298 DAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKD 350 >gi|162461738 guanine nucleotide binding protein, alpha activating polypeptide O isoform b [Homo sapiens] Length = 354 Score = 277 bits (708), Expect = 1e-74 Identities = 148/345 (42%), Positives = 219/345 (63%), Gaps = 5/345 (1%) Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92 ER A RS+ I+ L + + + VK+LLLGAGESGKST +KQM+IIH F + + + Sbjct: 9 ERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQ 68 Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLP-VEPATFQLYV 151 ++ ++ N ++ +V A D LGI +Y + E+ M + + + EP + +L + Sbjct: 69 YKPVVYSNTIQSLAAIVRAMDTLGI--EYGDKERKADAKMVCDVVSRMEDTEPFSAEL-L 125 Query: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211 A+ LW DSGI+E F+R E+QL +S KY+LD+LDRIG +Y P++QDIL R T GI Sbjct: 126 SAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGI 185 Query: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271 VE F K + F++ DVGGQRS+R+KW CF+ +T+I+F V+ S YDQVL ED TNR+ Sbjct: 186 VETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMH 245 Query: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331 ES+ +F++I NNK F + SIILFLNK D+ EK+K + FP++ G P + Y+ Sbjct: 246 ESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTG-PSAFTEAVAYI 304 Query: 332 VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLK 376 ++ K ++ K ++ H T A DT N++FVF AV D I+ +NL+ Sbjct: 305 QAQYESKNKSAHKEIYTHVTCATDTNNIQFVFDAVTDVIIAKNLR 349 >gi|20330805 guanine nucleotide binding protein, alpha transducing activity polypeptide 2 [Homo sapiens] Length = 354 Score = 274 bits (701), Expect = 8e-74 Identities = 147/354 (41%), Positives = 214/354 (60%), Gaps = 7/354 (1%) Query: 26 GSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF 85 GSGA ++E +RS++++ L + + VK+LLLGAGESGKST +KQM+IIH + Sbjct: 2 GSGASAEDKELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGY 61 Query: 86 DQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPA 145 + LEF+ I+ N+L+ ++ A LGI + G L N +E Sbjct: 62 SPEECLEFKAIIYGNVLQSILAIIRAMTTLGIDYAEPSCADDGRQL----NNLADSIEEG 117 Query: 146 TFQL-YVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLA 204 T V + LW+D G++ F R +E+QL +S Y+L+ L+RI Y PS+QD+L + Sbjct: 118 TMPPELVEVIRRLWKDGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLPSEQDVLRS 177 Query: 205 RKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMED 264 R T GI+E F +K + F+M DVGGQRS+R+KW CF+G+T I+F + S YD VL+ED Sbjct: 178 RVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVED 237 Query: 265 RRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRL 324 NR+ ES+++F +I N+K F SI+LFLNK DL EK+K V + FP++ G+ + Sbjct: 238 DEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGN-NSY 296 Query: 325 EDVQRYL-VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377 +D Y+ Q D R K ++ H T A DT+NV+FVF AV D I++ENLKD Sbjct: 297 DDAGNYIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKD 350 >gi|33946324 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 [Homo sapiens] Length = 354 Score = 271 bits (693), Expect = 7e-73 Identities = 147/348 (42%), Positives = 218/348 (62%), Gaps = 9/348 (2%) Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92 ++ A RS+ ID L + R VK+LLLGAGESGKST +KQM+IIH + ++ + Sbjct: 9 DKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQ 68 Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSE--NEKHGMFLMAFENKAGLPVEPATFQLY 150 ++ ++ N ++ ++ A +L I + S ++ +F++A + G T +L Sbjct: 69 YKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGF----MTAEL- 123 Query: 151 VPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKG 210 + LW+DSG++ F+R E+QL +S Y+L++LDRI Q NY P++QD+L R T G Sbjct: 124 AGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTG 183 Query: 211 IVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRL 270 IVE F K + FKM DVGGQRS+R+KW CF+G+T+I+F V+ S+YD VL ED NR+ Sbjct: 184 IVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRM 243 Query: 271 VESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRY 330 ESM +F++I NNK F + SIILFLNK DL EK+K + +P++ G + E+ Y Sbjct: 244 HESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGS-NTYEEAAAY 302 Query: 331 L-VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377 + Q D +R +K ++ HFT A DT+NV+FVF AV D I++ NLKD Sbjct: 303 IQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKD 350 >gi|4504051 guanine nucleotide binding protein, alpha z polypeptide [Homo sapiens] Length = 355 Score = 271 bits (692), Expect = 9e-73 Identities = 149/349 (42%), Positives = 214/349 (61%), Gaps = 4/349 (1%) Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92 E+EA RRSR ID L E + RR +K+LLLG SGKST +KQM+IIH F+ +A E Sbjct: 9 EKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKE 68 Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQLYVP 152 ++ I N + ++ A L I + + + L A A E L V Sbjct: 69 YKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGV- 127 Query: 153 ALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIV 212 + LW D G + FSR SE+ L ++ Y+L++L+RI +Y P+ +DIL +R T GIV Sbjct: 128 -MRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIV 186 Query: 213 EHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVE 272 E+ F K++ FKMVDVGGQRS+R+KW CF+G+T+I+F V S YD L ED +T+R+ E Sbjct: 187 ENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAE 246 Query: 273 SMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLV 332 S+ +F++I NN F N S+ILFLNK DLL EK++ + + FP+++G + E+ Y+ Sbjct: 247 SLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQ-NTYEEAAVYIQ 305 Query: 333 QCFDRKRRNR-SKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380 + F+ RN+ +K ++ HFT A DT N++FVF AV D I+Q NLK I L Sbjct: 306 RQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGL 354 >gi|156104883 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) [Homo sapiens] Length = 374 Score = 270 bits (691), Expect = 1e-72 Identities = 141/361 (39%), Positives = 223/361 (61%), Gaps = 18/361 (4%) Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92 E+ A R ++I+ +L +++ R +K+LLLG GESGKSTF+KQMRIIHG + ++ Sbjct: 18 EKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKG 77 Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQL-YV 151 FR ++ NI R +++A ++L IP+ E++ H +M+ + P + TF+ Y Sbjct: 78 FRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD-----PYKVTTFEKRYA 132 Query: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211 A+ LWRD+GIR + RR EF L +S Y+L +L+RI + Y P+ QD+L +R T GI Sbjct: 133 AAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGI 192 Query: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271 E+ F ++K ++VDVGGQ+S+R+KW CF+ + +++++ S SEYDQ L E+ + NR+ Sbjct: 193 NEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMK 252 Query: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331 ES+ +F TI+ F + S+ILFLNK D+L EK+ T + +FP F+G E +R++ Sbjct: 253 ESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFI 312 Query: 332 VQCFDR------------KRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIM 379 + + R K+ RS+ LF H+T A DT+N+R VF V+D++L L +I Sbjct: 313 LDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEIN 372 Query: 380 L 380 L Sbjct: 373 L 373 >gi|5729850 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 [Homo sapiens] Length = 354 Score = 268 bits (685), Expect = 6e-72 Identities = 145/346 (41%), Positives = 207/346 (59%), Gaps = 5/346 (1%) Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92 ++ A RS+ ID L + + VK+LLLGAGESGKST +KQM+IIH + + + Sbjct: 9 DKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQ 68 Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQLYVP 152 ++ ++ N ++ ++ A +L I + + L AG E Sbjct: 69 YKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVL---AGSAEEGVMTPELAG 125 Query: 153 ALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIV 212 + LWRD G++ FSR E+QL +S Y+L++LDRI Q NY P++QD+L R T GIV Sbjct: 126 VIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIV 185 Query: 213 EHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVE 272 E F K + FKM DVGGQRS+R+KW CF+G+T+I+F V+ S+YD VL ED NR+ E Sbjct: 186 ETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHE 245 Query: 273 SMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL- 331 SM +F++I NNK F SIILFLNK DL EK+K + +P++ G + E+ Y+ Sbjct: 246 SMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGS-NTYEEAAAYIQ 304 Query: 332 VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377 Q D RR +K ++ HFT A DT+NV+FVF AV D I++ NLK+ Sbjct: 305 CQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKE 350 >gi|22027522 rod-type transducin alpha subunit [Homo sapiens] Length = 350 Score = 264 bits (674), Expect = 1e-70 Identities = 146/353 (41%), Positives = 208/353 (58%), Gaps = 9/353 (2%) Query: 26 GSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF 85 G+GA E+ SR+++ L + R VK+LLLGAGESGKST +KQM+IIH + Sbjct: 2 GAGASAEEKH----SRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGY 57 Query: 86 DQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPA 145 + LEF I+ N L+ +V A L I + S + LM + P Sbjct: 58 SLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPK 117 Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205 + LW+DSGI+ F R SE+QL +S Y+L +L+R+ Y P++QD+L +R Sbjct: 118 EMS---DIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSR 174 Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265 T GI+E F K + F+M DVGGQRS+R+KW CF+G+T I+F+ + S YD VL+ED Sbjct: 175 VKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDD 234 Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLE 325 NR+ ES+++F +I N++ F SI+LFLNK D+ EK+K + FPD+ G P+ E Sbjct: 235 EVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKIKKAHLSICFPDYDG-PNTYE 293 Query: 326 DVQRYL-VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377 D Y+ VQ + R K ++ H T A DT+NV+FVF AV D I++ENLKD Sbjct: 294 DAGNYIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKD 346 >gi|22027520 rod-type transducin alpha subunit [Homo sapiens] Length = 350 Score = 264 bits (674), Expect = 1e-70 Identities = 146/353 (41%), Positives = 208/353 (58%), Gaps = 9/353 (2%) Query: 26 GSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF 85 G+GA E+ SR+++ L + R VK+LLLGAGESGKST +KQM+IIH + Sbjct: 2 GAGASAEEKH----SRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGY 57 Query: 86 DQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPA 145 + LEF I+ N L+ +V A L I + S + LM + P Sbjct: 58 SLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPK 117 Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205 + LW+DSGI+ F R SE+QL +S Y+L +L+R+ Y P++QD+L +R Sbjct: 118 EMS---DIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSR 174 Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265 T GI+E F K + F+M DVGGQRS+R+KW CF+G+T I+F+ + S YD VL+ED Sbjct: 175 VKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDD 234 Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLE 325 NR+ ES+++F +I N++ F SI+LFLNK D+ EK+K + FPD+ G P+ E Sbjct: 235 EVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKIKKAHLSICFPDYDG-PNTYE 293 Query: 326 DVQRYL-VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377 D Y+ VQ + R K ++ H T A DT+NV+FVF AV D I++ENLKD Sbjct: 294 DAGNYIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKD 346 >gi|4504041 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 [Homo sapiens] Length = 355 Score = 262 bits (669), Expect = 4e-70 Identities = 144/350 (41%), Positives = 208/350 (59%), Gaps = 12/350 (3%) Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92 ++ A RS+ ID L + R VK+LLLGAGESGKST +KQM+IIH + ++ + Sbjct: 9 DKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQ 68 Query: 93 FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAF----ENKAGLPVEPATFQ 148 +R ++ N ++ +V A L I + L A E + LP + + Sbjct: 69 YRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSG-- 126 Query: 149 LYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKAT 208 + LW D G++ F R E+QL +S Y+L++L+RI Q +Y P++QD+L R T Sbjct: 127 ----VIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKT 182 Query: 209 KGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTN 268 GIVE F K + FKM DVGGQRS+R+KW CF+G+T+I+F V+ S YD VL ED N Sbjct: 183 TGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMN 242 Query: 269 RLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQ 328 R+ ESM +F++I NNK F + SIILFLNK DL EK+ + FP++ G ++ ++ Sbjct: 243 RMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTG-ANKYDEAA 301 Query: 329 RYLVQCF-DRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377 Y+ F D +R +K ++ HFT A DT+NV+FVF AV D I++ NLKD Sbjct: 302 SYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKD 351 >gi|117938765 GNAS complex locus isoform g [Homo sapiens] Length = 379 Score = 231 bits (589), Expect = 8e-61 Identities = 137/370 (37%), Positives = 207/370 (55%), Gaps = 23/370 (6%) Query: 30 RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKA 89 R+ E+ R ++ I+ L ++++ R ++LLLGAGESGKST +KQMRI+H F+ Sbjct: 13 RNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDE 72 Query: 90 LLEFRDTIFDNILKGSRVLVDARDKLGIPWQYS--ENEKHGMFLMAFENKAGLPVEPATF 147 I +N+ + +V A L P + + EN+ ++++ N P + Sbjct: 73 KATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFY 132 Query: 148 QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKA 207 + ALW D G+R + R +E+QL + +YFLD +D I Q +Y PS QD+L R Sbjct: 133 E----HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVL 188 Query: 208 TKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRT 267 T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+F+V+SS Y+ V+ ED +T Sbjct: 189 TSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQT 248 Query: 268 NRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFR------- 318 NRL E++N+F++I NN+ +S+ILFLNK DLL EKV I+ +FP+F Sbjct: 249 NRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPED 308 Query: 319 GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTENVRFVFHAVKDTI 370 P ED + + F R R + HFT A+DTEN+R VF+ +D I Sbjct: 309 ATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDII 368 Query: 371 LQENLKDIML 380 + +L+ L Sbjct: 369 QRMHLRQYEL 378 >gi|18426900 GNAS complex locus GNASS [Homo sapiens] Length = 380 Score = 231 bits (589), Expect = 8e-61 Identities = 139/372 (37%), Positives = 211/372 (56%), Gaps = 26/372 (6%) Query: 30 RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF--DQ 87 R+ E+ R ++ I+ L ++++ R ++LLLGAGESGKST +KQMRI+H F D Sbjct: 13 RNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDS 72 Query: 88 KALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYS--ENEKHGMFLMAFENKAGLPVEPA 145 + + +D I +N+ + +V A L P + + EN+ ++++ N P Sbjct: 73 EKATKVQD-IKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPE 131 Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205 ++ ALW D G+R + R +E+QL + +YFLD +D I Q +Y PS QD+L R Sbjct: 132 FYE----HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCR 187 Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265 T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+F+V+SS Y+ V+ ED Sbjct: 188 VLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDN 247 Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFR----- 318 +TNRL E++N+F++I NN+ +S+ILFLNK DLL EKV I+ +FP+F Sbjct: 248 QTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTP 307 Query: 319 --GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTENVRFVFHAVKD 368 P ED + + F R R + HFT A+DTEN+R VF+ +D Sbjct: 308 EDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRD 367 Query: 369 TILQENLKDIML 380 I + +L+ L Sbjct: 368 IIQRMHLRQYEL 379 >gi|33695153 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type isoform 1 [Homo sapiens] Length = 458 Score = 228 bits (582), Expect = 5e-60 Identities = 139/383 (36%), Positives = 217/383 (56%), Gaps = 33/383 (8%) Query: 22 ERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIH 81 E R + R+A +EAR+ SR ID +L ++R +++ ++LLLGAGESGKST +KQMRI+H Sbjct: 84 EEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILH 143 Query: 82 GREFD----QKALLEFRDTIFDNILKGSRVLVDARDKL--GIPWQYSENEKHGMFLMAFE 135 F+ ++ +L+ R + D I+ +V A + +P EN+ ++ Sbjct: 144 VNGFNPEEKKQKILDIRKNVKDAIV----TIVSAMSTIIPPVPLANPENQFRSDYI---- 195 Query: 136 NKAGLPVEPATF-QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNY 194 K+ P+ + Q + + LW D G++ F R +E+QL + +YFL+ +D + ++Y Sbjct: 196 -KSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDY 254 Query: 195 FPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSS 254 P+ QD+L R T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+++ + Sbjct: 255 TPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAAC 314 Query: 255 SEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKK 312 S Y+ V+ ED TNRL ES+++FE+I NN+ +SIILFLNK D+L EKV I+ Sbjct: 315 SSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIED 374 Query: 313 HFPDFR-------GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTE 357 +FP++ P ED + + F R R + HFT A+DTE Sbjct: 375 YFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTE 434 Query: 358 NVRFVFHAVKDTILQENLKDIML 380 N+R VF+ +D I + +LK L Sbjct: 435 NIRRVFNDCRDIIQRMHLKQYEL 457 >gi|4504047 GNAS complex locus GNASL [Homo sapiens] Length = 394 Score = 227 bits (579), Expect = 1e-59 Identities = 141/385 (36%), Positives = 211/385 (54%), Gaps = 38/385 (9%) Query: 30 RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIH-------G 82 R+ E+ R ++ I+ L ++++ R ++LLLGAGESGKST +KQMRI+H G Sbjct: 13 RNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEG 72 Query: 83 REFDQKALLEFRD--------TIFDNILKGSRVLVDARDKLGIPWQYS--ENEKHGMFLM 132 E D +A D I +N+ + +V A L P + + EN+ +++ Sbjct: 73 GEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYIL 132 Query: 133 AFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQL 192 + N P ++ ALW D G+R + R +E+QL + +YFLD +D I Q Sbjct: 133 SVMNVPDFDFPPEFYE----HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQA 188 Query: 193 NYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMV 252 +Y PS QD+L R T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+F+V Sbjct: 189 DYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVV 248 Query: 253 SSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSI 310 +SS Y+ V+ ED +TNRL E++N+F++I NN+ +S+ILFLNK DLL EKV I Sbjct: 249 ASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKI 308 Query: 311 KKHFPDFR-------GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAID 355 + +FP+F P ED + + F R R + HFT A+D Sbjct: 309 EDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVD 368 Query: 356 TENVRFVFHAVKDTILQENLKDIML 380 TEN+R VF+ +D I + +L+ L Sbjct: 369 TENIRRVFNDCRDIIQRMHLRQYEL 393 >gi|117938762 GNAS complex locus isoform f [Homo sapiens] Length = 395 Score = 227 bits (578), Expect = 2e-59 Identities = 141/386 (36%), Positives = 211/386 (54%), Gaps = 39/386 (10%) Query: 30 RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIH-------G 82 R+ E+ R ++ I+ L ++++ R ++LLLGAGESGKST +KQMRI+H G Sbjct: 13 RNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEG 72 Query: 83 REFDQKALLEFRD---------TIFDNILKGSRVLVDARDKLGIPWQYS--ENEKHGMFL 131 E D +A D I +N+ + +V A L P + + EN+ ++ Sbjct: 73 GEEDPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYI 132 Query: 132 MAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQ 191 ++ N P ++ ALW D G+R + R +E+QL + +YFLD +D I Q Sbjct: 133 LSVMNVPDFDFPPEFYE----HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQ 188 Query: 192 LNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFM 251 +Y PS QD+L R T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+F+ Sbjct: 189 ADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFV 248 Query: 252 VSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VS 309 V+SS Y+ V+ ED +TNRL E++N+F++I NN+ +S+ILFLNK DLL EKV Sbjct: 249 VASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSK 308 Query: 310 IKKHFPDFR-------GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAI 354 I+ +FP+F P ED + + F R R + HFT A+ Sbjct: 309 IEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAV 368 Query: 355 DTENVRFVFHAVKDTILQENLKDIML 380 DTEN+R VF+ +D I + +L+ L Sbjct: 369 DTENIRRVFNDCRDIIQRMHLRQYEL 394 >gi|117938759 GNAS complex locus XLas [Homo sapiens] Length = 1037 Score = 226 bits (575), Expect = 3e-59 Identities = 147/409 (35%), Positives = 217/409 (53%), Gaps = 38/409 (9%) Query: 6 RTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGA 65 R+L +P + R+ R +R ++RS+ ID L E+ ++LLLGA Sbjct: 632 RSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGA 691 Query: 66 GESGKSTFLKQMRIIH-------GREFDQKALLEFRD--------TIFDNILKGSRVLVD 110 GESGKST +KQMRI+H G E D +A D I +N+ + +V Sbjct: 692 GESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVA 751 Query: 111 ARDKLGIPWQYS--ENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFS 168 A L P + + EN+ ++++ N P ++ ALW D G+R + Sbjct: 752 AMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYE----HAKALWEDEGVRACYE 807 Query: 169 RRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDV 228 R +E+QL + +YFLD +D I Q +Y PS QD+L R T GI E F + K+ F M DV Sbjct: 808 RSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDV 867 Query: 229 GGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFN 288 GGQR +R+KW QCF+ +T+I+F+V+SS Y+ V+ ED +TNRL E++N+F++I NN+ Sbjct: 868 GGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRT 927 Query: 289 VSIILFLNKMDLLVEKVKT--VSIKKHFPDFR-------GDPHRLEDVQRYLVQCFDRKR 339 +S+ILFLNK DLL EKV I+ +FP+F P ED + + F R Sbjct: 928 ISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDE 987 Query: 340 RNRSKP--------LFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380 R + HFT A+DTEN+R VF+ +D I + +L+ L Sbjct: 988 FLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYEL 1036 >gi|4504043 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type isoform 2 [Homo sapiens] Length = 381 Score = 219 bits (558), Expect = 3e-57 Identities = 134/372 (36%), Positives = 208/372 (55%), Gaps = 33/372 (8%) Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFD----QK 88 E+E R ++ I+ L +ER A + ++LLLGAGESGKST +KQMRI+H F+ ++ Sbjct: 18 EKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQ 77 Query: 89 ALLEFRDTIFDNILKGSRVLVDARDKL--GIPWQYSENEKHGMFLMAFENKAGLPVEPAT 146 +L+ R + D I+ +V A + +P EN+ ++ K+ P+ Sbjct: 78 KILDIRKNVKDAIV----TIVSAMSTIIPPVPLANPENQFRSDYI-----KSIAPITDFE 128 Query: 147 F-QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205 + Q + + LW D G++ F R +E+QL + +YFL+ +D + ++Y P+ QD+L R Sbjct: 129 YSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCR 188 Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265 T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+++ + S Y+ V+ ED Sbjct: 189 VLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDN 248 Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFR----- 318 TNRL ES+++FE+I NN+ +SIILFLNK D+L EKV I+ +FP++ Sbjct: 249 NTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVP 308 Query: 319 --GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTENVRFVFHAVKD 368 P ED + + F R R + HFT A+DTEN+R VF+ +D Sbjct: 309 EDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRD 368 Query: 369 TILQENLKDIML 380 I + +LK L Sbjct: 369 IIQRMHLKQYEL 380 >gi|215272301 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type isoform 2 [Homo sapiens] Length = 381 Score = 219 bits (558), Expect = 3e-57 Identities = 134/372 (36%), Positives = 208/372 (55%), Gaps = 33/372 (8%) Query: 33 EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFD----QK 88 E+E R ++ I+ L +ER A + ++LLLGAGESGKST +KQMRI+H F+ ++ Sbjct: 18 EKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQ 77 Query: 89 ALLEFRDTIFDNILKGSRVLVDARDKL--GIPWQYSENEKHGMFLMAFENKAGLPVEPAT 146 +L+ R + D I+ +V A + +P EN+ ++ K+ P+ Sbjct: 78 KILDIRKNVKDAIV----TIVSAMSTIIPPVPLANPENQFRSDYI-----KSIAPITDFE 128 Query: 147 F-QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205 + Q + + LW D G++ F R +E+QL + +YFL+ +D + ++Y P+ QD+L R Sbjct: 129 YSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCR 188 Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265 T GI E F + K+ F M DVGGQR +R+KW QCF+ +T+I+++ + S Y+ V+ ED Sbjct: 189 VLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDN 248 Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFR----- 318 TNRL ES+++FE+I NN+ +SIILFLNK D+L EKV I+ +FP++ Sbjct: 249 NTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVP 308 Query: 319 --GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTENVRFVFHAVKD 368 P ED + + F R R + HFT A+DTEN+R VF+ +D Sbjct: 309 EDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRD 368 Query: 369 TILQENLKDIML 380 I + +LK L Sbjct: 369 IIQRMHLKQYEL 380 >gi|4502211 ADP-ribosylation factor 6 [Homo sapiens] Length = 175 Score = 41.6 bits (96), Expect = 0.001 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 10/93 (10%) Query: 208 TKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRT 267 T G K + F + DVGGQ R W + G ++F+V ++ D Sbjct: 44 TVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD--------- 94 Query: 268 NRLVESMNIFETIVNNKLFFNVSIILFLNKMDL 300 R+ E+ I+N++ + I++F NK DL Sbjct: 95 -RIDEARQELHRIINDREMRDAIILIFANKQDL 126 >gi|7705827 SAR1a gene homolog 2 [Homo sapiens] Length = 198 Score = 40.4 bits (93), Expect = 0.003 Identities = 31/124 (25%), Positives = 54/124 (43%), Gaps = 12/124 (9%) Query: 176 GESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQR 235 G+ V LDN + L+ K D L T + I + F D+GG R Sbjct: 26 GKLVFLGLDNAGKTTLLHML--KDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQAR 83 Query: 236 QKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFL 295 + W I I+F+V ++++ RL+ES ++++ ++ NV I++ Sbjct: 84 RVWKNYLPAINGIVFLVDCADHE----------RLLESKEELDSLMTDETIANVPILILG 133 Query: 296 NKMD 299 NK+D Sbjct: 134 NKID 137 >gi|75709204 SAR1a gene homolog 2 [Homo sapiens] Length = 198 Score = 40.4 bits (93), Expect = 0.003 Identities = 31/124 (25%), Positives = 54/124 (43%), Gaps = 12/124 (9%) Query: 176 GESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQR 235 G+ V LDN + L+ K D L T + I + F D+GG R Sbjct: 26 GKLVFLGLDNAGKTTLLHML--KDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQAR 83 Query: 236 QKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFL 295 + W I I+F+V ++++ RL+ES ++++ ++ NV I++ Sbjct: 84 RVWKNYLPAINGIVFLVDCADHE----------RLLESKEELDSLMTDETIANVPILILG 133 Query: 296 NKMD 299 NK+D Sbjct: 134 NKID 137 >gi|217416369 SAR1a gene homolog 1 [Homo sapiens] Length = 198 Score = 40.0 bits (92), Expect = 0.003 Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 12/124 (9%) Query: 176 GESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQR 235 G+ V LDN + L+ K D L T + I + F D+GG R Sbjct: 26 GKLVFLGLDNAGKTTLLHML--KDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQAR 83 Query: 236 QKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFL 295 + W I I+F+V +++ +RLVES ++ ++ NV I++ Sbjct: 84 RVWKNYLPAINGIVFLVDCADH----------SRLVESKVELNALMTDETISNVPILILG 133 Query: 296 NKMD 299 NK+D Sbjct: 134 NKID 137 >gi|9910542 SAR1a gene homolog 1 [Homo sapiens] Length = 198 Score = 40.0 bits (92), Expect = 0.003 Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 12/124 (9%) Query: 176 GESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQR 235 G+ V LDN + L+ K D L T + I + F D+GG R Sbjct: 26 GKLVFLGLDNAGKTTLLHML--KDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQAR 83 Query: 236 QKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFL 295 + W I I+F+V +++ +RLVES ++ ++ NV I++ Sbjct: 84 RVWKNYLPAINGIVFLVDCADH----------SRLVESKVELNALMTDETISNVPILILG 133 Query: 296 NKMD 299 NK+D Sbjct: 134 NKID 137 >gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma [Homo sapiens] Length = 546 Score = 40.0 bits (92), Expect = 0.003 Identities = 33/144 (22%), Positives = 60/144 (41%), Gaps = 13/144 (9%) Query: 160 DSGIREAFSRRSEFQLGES--VKYFLDNLDRIGQLNY-FPSKQDILLARKATKGIVEHDF 216 D+ I F++ + +G ++ LD G+ F KQD + T G Sbjct: 384 DASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETV 443 Query: 217 VIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNI 276 K + F + DVGG+ R W + +++F+V SS D R+ E+ + Sbjct: 444 EYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRD----------RISEAHSE 493 Query: 277 FETIVNNKLFFNVSIILFLNKMDL 300 ++ K + +++F NK D+ Sbjct: 494 LAKLLTEKELRDALLLIFANKQDV 517 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.325 0.140 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,303,583 Number of Sequences: 37866 Number of extensions: 503874 Number of successful extensions: 2168 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 53 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 2061 Number of HSP's gapped (non-prelim): 90 length of query: 381 length of database: 18,247,518 effective HSP length: 104 effective length of query: 277 effective length of database: 14,309,454 effective search space: 3963718758 effective search space used: 3963718758 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.