Guide to the Human Genome
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Search of human proteins with 42476111

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42476111 guanine nucleotide binding protein (G protein)
alpha 12 [Homo sapiens]
         (381 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42476111 guanine nucleotide binding protein (G protein) alpha...   753   0.0  
gi|24111250 guanine nucleotide binding protein (G protein), alph...   476   e-134
gi|40254462 guanine nucleotide binding protein (G protein), q po...   303   2e-82
gi|115511049 guanine nucleotide binding protein (G protein), alp...   299   3e-81
gi|4758444 G alpha 14 [Homo sapiens]                                  289   3e-78
gi|10567816 guanine nucleotide binding protein, alpha activating...   282   4e-76
gi|156139155 guanine nucleotide binding protein, alpha transduci...   280   2e-75
gi|162461738 guanine nucleotide binding protein, alpha activatin...   277   1e-74
gi|20330805 guanine nucleotide binding protein, alpha transducin...   274   8e-74
gi|33946324 guanine nucleotide binding protein (G protein), alph...   271   7e-73
gi|4504051 guanine nucleotide binding protein, alpha z polypepti...   271   9e-73
gi|156104883 guanine nucleotide binding protein (G protein), alp...   270   1e-72
gi|5729850 guanine nucleotide binding protein (G protein), alpha...   268   6e-72
gi|22027522 rod-type transducin alpha subunit [Homo sapiens]          264   1e-70
gi|22027520 rod-type transducin alpha subunit [Homo sapiens]          264   1e-70
gi|4504041 guanine nucleotide binding protein (G protein), alpha...   262   4e-70
gi|117938765 GNAS complex locus isoform g [Homo sapiens]              231   8e-61
gi|18426900 GNAS complex locus GNASS [Homo sapiens]                   231   8e-61
gi|33695153 guanine nucleotide binding protein (G protein), alph...   228   5e-60
gi|4504047 GNAS complex locus GNASL [Homo sapiens]                    227   1e-59
gi|117938762 GNAS complex locus isoform f [Homo sapiens]              227   2e-59
gi|117938759 GNAS complex locus XLas [Homo sapiens]                   226   3e-59
gi|4504043 guanine nucleotide binding protein (G protein), alpha...   219   3e-57
gi|215272301 guanine nucleotide binding protein (G protein), alp...   219   3e-57
gi|4502211 ADP-ribosylation factor 6 [Homo sapiens]                    42   0.001
gi|7705827 SAR1a gene homolog 2 [Homo sapiens]                         40   0.003
gi|75709204 SAR1a gene homolog 2 [Homo sapiens]                        40   0.003
gi|217416369 SAR1a gene homolog 1 [Homo sapiens]                       40   0.003
gi|9910542 SAR1a gene homolog 1 [Homo sapiens]                         40   0.003
gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam...    40   0.003

>gi|42476111 guanine nucleotide binding protein (G protein) alpha 12
           [Homo sapiens]
          Length = 381

 Score =  753 bits (1943), Expect = 0.0
 Identities = 381/381 (100%), Positives = 381/381 (100%)

Query: 1   MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI 60
           MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI
Sbjct: 1   MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI 60

Query: 61  LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ 120
           LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ
Sbjct: 61  LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ 120

Query: 121 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK 180
           YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK
Sbjct: 121 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK 180

Query: 181 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ 240
           YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ
Sbjct: 181 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ 240

Query: 241 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL 300
           CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL
Sbjct: 241 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL 300

Query: 301 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR 360
           LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR
Sbjct: 301 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR 360

Query: 361 FVFHAVKDTILQENLKDIMLQ 381
           FVFHAVKDTILQENLKDIMLQ
Sbjct: 361 FVFHAVKDTILQENLKDIMLQ 381


>gi|24111250 guanine nucleotide binding protein (G protein), alpha
           13 [Homo sapiens]
          Length = 377

 Score =  476 bits (1226), Expect = e-134
 Identities = 236/354 (66%), Positives = 293/354 (82%), Gaps = 5/354 (1%)

Query: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
           E E +R+S++ID  L+RE+  V+RLVKILLLGAGESGKSTFLKQMRIIHG++FDQ+A  E
Sbjct: 24  EAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREE 83

Query: 93  FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLP----VEPATFQ 148
           FR TI+ N++KG RVLVDAR+KL IPW  + N++HG  +M+F+ +A +     VE   F 
Sbjct: 84  FRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFL 143

Query: 149 LYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKAT 208
            Y+PA+ ALW DSGI+ A+ RR EFQLGESVKYFLDNLD++G+ +Y PS+QDILLAR+ T
Sbjct: 144 QYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPT 203

Query: 209 KGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTN 268
           KGI E+DF IK +PFKMVDVGGQRS+R++WF+CFD +TSILF+VSSSE+DQVLMEDR TN
Sbjct: 204 KGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTN 263

Query: 269 RLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQ 328
           RL ES+NIFETIVNN++F NVSIILFLNK DLL EKV+ VSIK +F +F GDPH L DVQ
Sbjct: 264 RLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPHCLRDVQ 323

Query: 329 RYLVQCFDRKRRN-RSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ 381
           ++LV+CF  KRR+ + KPL+HHFTTAI+TEN+R VF  VKDTIL +NLK +MLQ
Sbjct: 324 KFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ 377


>gi|40254462 guanine nucleotide binding protein (G protein), q
           polypeptide [Homo sapiens]
          Length = 359

 Score =  303 bits (776), Expect = 2e-82
 Identities = 156/355 (43%), Positives = 223/355 (62%), Gaps = 20/355 (5%)

Query: 34  REARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEF 93
           +EARR + +I+  L R++R  RR +K+LLLG GESGKSTF+KQMRIIHG  +  +    F
Sbjct: 16  KEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGF 75

Query: 94  RDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLM--------AFENKAGLPVEPA 145
              ++ NI    + ++ A D L IP++Y  N+ H   +         AFEN         
Sbjct: 76  TKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENP-------- 127

Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
               YV A+ +LW D GI+E + RR E+QL +S KY+L++LDR+    Y P++QD+L  R
Sbjct: 128 ----YVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVR 183

Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
             T GI+E+ F ++ + F+MVDVGGQRS+R+KW  CF+ +TSI+F+V+ SEYDQVL+E  
Sbjct: 184 VPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESD 243

Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLE 325
             NR+ ES  +F TI+    F N S+ILFLNK DLL EK+    +  +FP++ G     +
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQ 303

Query: 326 DVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380
             + ++++ F     +  K ++ HFT A DTEN+RFVF AVKDTILQ NLK+  L
Sbjct: 304 AAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL 358


>gi|115511049 guanine nucleotide binding protein (G protein), alpha
           11 (Gq class) [Homo sapiens]
          Length = 359

 Score =  299 bits (765), Expect = 3e-81
 Identities = 152/351 (43%), Positives = 227/351 (64%), Gaps = 6/351 (1%)

Query: 31  DAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKAL 90
           D  +E++R + +I+  L R++R  RR +K+LLLG GESGKSTF+KQMRIIHG  + ++  
Sbjct: 13  DEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDK 72

Query: 91  LEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQ-L 149
             F   ++ NI    + ++ A + L I ++Y +N+ + + +   + +     +  TF+  
Sbjct: 73  RGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVE-----KVTTFEHQ 127

Query: 150 YVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATK 209
           YV A+  LW D GI+E + RR E+QL +S KY+L ++DRI  L Y P++QD+L  R  T 
Sbjct: 128 YVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVLRVRVPTT 187

Query: 210 GIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNR 269
           GI+E+ F ++ I F+MVDVGGQRS+R+KW  CF+ +TSI+F+V+ SEYDQVL+E    NR
Sbjct: 188 GIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENR 247

Query: 270 LVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQR 329
           + ES  +F TI+    F N S+ILFLNK DLL +K+    +  +FP+F G     +  + 
Sbjct: 248 MEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQRDAQAARE 307

Query: 330 YLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380
           ++++ F     +  K ++ HFT A DTEN+RFVF AVKDTILQ NLK+  L
Sbjct: 308 FILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL 358


>gi|4758444 G alpha 14 [Homo sapiens]
          Length = 355

 Score =  289 bits (739), Expect = 3e-78
 Identities = 146/349 (41%), Positives = 225/349 (64%), Gaps = 6/349 (1%)

Query: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
           E+E++R S +I+  L R+++  RR +K+LLLG GESGKSTF+KQMRIIHG  +  +    
Sbjct: 11  EKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKG 70

Query: 93  FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFE-NKAGLPVEPATFQLYV 151
           F   ++ NI    + ++ A D L I +   +N+++   +   E +K  +       +  V
Sbjct: 71  FTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSM-----LSREQV 125

Query: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211
            A+  LW+D GI+E + RR E+QL +S KY+L ++DRI   ++ P++QD+L  R  T GI
Sbjct: 126 EAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGI 185

Query: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271
           +E+ F ++ I F+MVDVGGQRS+R+KW  CF+ +TSI+F+V+ SEYDQVL E    NR+ 
Sbjct: 186 IEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRME 245

Query: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331
           ES  +F+TI+    F N S+ILFLNK DLL EK+    +  +FP++ G    +   + ++
Sbjct: 246 ESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRAARDFI 305

Query: 332 VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380
           ++ +  +  ++ K ++ HFT A DT+N+RFVF AVKDTILQ NL++  L
Sbjct: 306 LKLYQDQNPDKEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNLREFNL 354


>gi|10567816 guanine nucleotide binding protein, alpha activating
           polypeptide O isoform a [Homo sapiens]
          Length = 354

 Score =  282 bits (721), Expect = 4e-76
 Identities = 152/345 (44%), Positives = 220/345 (63%), Gaps = 5/345 (1%)

Query: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
           ER A  RS+ I+  L  +  +  + VK+LLLGAGESGKST +KQM+IIH   F  + + +
Sbjct: 9   ERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQ 68

Query: 93  FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLP-VEPATFQLYV 151
           ++  ++ N ++    +V A D LGI  +Y + E+     M  +  + +   EP + +L +
Sbjct: 69  YKPVVYSNTIQSLAAIVRAMDTLGI--EYGDKERKADAKMVCDVVSRMEDTEPFSAEL-L 125

Query: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211
            A+  LW DSGI+E F+R  E+QL +S KY+LD+LDRIG  +Y P++QDIL  R  T GI
Sbjct: 126 SAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGI 185

Query: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271
           VE  F  K + F++ DVGGQRS+R+KW  CF+ +T+I+F V+ S YDQVL ED  TNR+ 
Sbjct: 186 VETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMH 245

Query: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331
           ES+ +F++I NNK F + SIILFLNK DL  EK+K   +   FP++ G P+  ED   Y+
Sbjct: 246 ESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTG-PNTYEDAAAYI 304

Query: 332 VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLK 376
              F+ K R+ +K ++ H T A DT N++ VF AV D I+  NL+
Sbjct: 305 QAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLR 349


>gi|156139155 guanine nucleotide binding protein, alpha transducing
           3 [Homo sapiens]
          Length = 354

 Score =  280 bits (716), Expect = 2e-75
 Identities = 151/353 (42%), Positives = 214/353 (60%), Gaps = 5/353 (1%)

Query: 26  GSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF 85
           GSG     +E+ +RS++++  L  +     R VK+LLLGAGESGKST +KQM+IIH   +
Sbjct: 2   GSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGY 61

Query: 86  DQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPA 145
            ++  +EF+  I+ N L+    +V A   LGI +    + +    L A  N   L     
Sbjct: 62  SEQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMANT--LEDGGM 119

Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
           T QL    +  LWRD GI+  F R SE+QL +S  Y+L++LDRI    Y P++QD+L +R
Sbjct: 120 TPQL-AEVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSR 178

Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
             T GI+E  F  K + F+M DVGGQRS+R+KW  CF+G+T I+F  + S YD VL+ED 
Sbjct: 179 VKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDE 238

Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLE 325
             NR+ ES+++F +I N+K F   SI+LFLNK D+  EKV  V +   FP++ G P+  E
Sbjct: 239 EVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTKVHLSICFPEYTG-PNTFE 297

Query: 326 DVQRYLV-QCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
           D   Y+  Q  D   +   K ++ H T A DT+NV+FVF AV D I++ENLKD
Sbjct: 298 DAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKD 350


>gi|162461738 guanine nucleotide binding protein, alpha activating
           polypeptide O isoform b [Homo sapiens]
          Length = 354

 Score =  277 bits (708), Expect = 1e-74
 Identities = 148/345 (42%), Positives = 219/345 (63%), Gaps = 5/345 (1%)

Query: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
           ER A  RS+ I+  L  +  +  + VK+LLLGAGESGKST +KQM+IIH   F  + + +
Sbjct: 9   ERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQ 68

Query: 93  FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLP-VEPATFQLYV 151
           ++  ++ N ++    +V A D LGI  +Y + E+     M  +  + +   EP + +L +
Sbjct: 69  YKPVVYSNTIQSLAAIVRAMDTLGI--EYGDKERKADAKMVCDVVSRMEDTEPFSAEL-L 125

Query: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211
            A+  LW DSGI+E F+R  E+QL +S KY+LD+LDRIG  +Y P++QDIL  R  T GI
Sbjct: 126 SAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGI 185

Query: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271
           VE  F  K + F++ DVGGQRS+R+KW  CF+ +T+I+F V+ S YDQVL ED  TNR+ 
Sbjct: 186 VETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMH 245

Query: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331
           ES+ +F++I NNK F + SIILFLNK D+  EK+K   +   FP++ G P    +   Y+
Sbjct: 246 ESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTG-PSAFTEAVAYI 304

Query: 332 VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLK 376
              ++ K ++  K ++ H T A DT N++FVF AV D I+ +NL+
Sbjct: 305 QAQYESKNKSAHKEIYTHVTCATDTNNIQFVFDAVTDVIIAKNLR 349


>gi|20330805 guanine nucleotide binding protein, alpha transducing
           activity polypeptide 2 [Homo sapiens]
          Length = 354

 Score =  274 bits (701), Expect = 8e-74
 Identities = 147/354 (41%), Positives = 214/354 (60%), Gaps = 7/354 (1%)

Query: 26  GSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF 85
           GSGA   ++E  +RS++++  L  +     + VK+LLLGAGESGKST +KQM+IIH   +
Sbjct: 2   GSGASAEDKELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGY 61

Query: 86  DQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPA 145
             +  LEF+  I+ N+L+    ++ A   LGI +        G  L    N     +E  
Sbjct: 62  SPEECLEFKAIIYGNVLQSILAIIRAMTTLGIDYAEPSCADDGRQL----NNLADSIEEG 117

Query: 146 TFQL-YVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLA 204
           T     V  +  LW+D G++  F R +E+QL +S  Y+L+ L+RI    Y PS+QD+L +
Sbjct: 118 TMPPELVEVIRRLWKDGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLPSEQDVLRS 177

Query: 205 RKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMED 264
           R  T GI+E  F +K + F+M DVGGQRS+R+KW  CF+G+T I+F  + S YD VL+ED
Sbjct: 178 RVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVED 237

Query: 265 RRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRL 324
              NR+ ES+++F +I N+K F   SI+LFLNK DL  EK+K V +   FP++ G+ +  
Sbjct: 238 DEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGN-NSY 296

Query: 325 EDVQRYL-VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
           +D   Y+  Q  D   R   K ++ H T A DT+NV+FVF AV D I++ENLKD
Sbjct: 297 DDAGNYIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKD 350


>gi|33946324 guanine nucleotide binding protein (G protein), alpha
           inhibiting activity polypeptide 1 [Homo sapiens]
          Length = 354

 Score =  271 bits (693), Expect = 7e-73
 Identities = 147/348 (42%), Positives = 218/348 (62%), Gaps = 9/348 (2%)

Query: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
           ++ A  RS+ ID  L  +     R VK+LLLGAGESGKST +KQM+IIH   + ++   +
Sbjct: 9   DKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQ 68

Query: 93  FRDTIFDNILKGSRVLVDARDKLGIPWQYSE--NEKHGMFLMAFENKAGLPVEPATFQLY 150
           ++  ++ N ++    ++ A  +L I +  S   ++   +F++A   + G      T +L 
Sbjct: 69  YKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGF----MTAEL- 123

Query: 151 VPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKG 210
              +  LW+DSG++  F+R  E+QL +S  Y+L++LDRI Q NY P++QD+L  R  T G
Sbjct: 124 AGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTG 183

Query: 211 IVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRL 270
           IVE  F  K + FKM DVGGQRS+R+KW  CF+G+T+I+F V+ S+YD VL ED   NR+
Sbjct: 184 IVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRM 243

Query: 271 VESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRY 330
            ESM +F++I NNK F + SIILFLNK DL  EK+K   +   +P++ G  +  E+   Y
Sbjct: 244 HESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGS-NTYEEAAAY 302

Query: 331 L-VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
           +  Q  D  +R  +K ++ HFT A DT+NV+FVF AV D I++ NLKD
Sbjct: 303 IQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKD 350


>gi|4504051 guanine nucleotide binding protein, alpha z polypeptide
           [Homo sapiens]
          Length = 355

 Score =  271 bits (692), Expect = 9e-73
 Identities = 149/349 (42%), Positives = 214/349 (61%), Gaps = 4/349 (1%)

Query: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
           E+EA RRSR ID  L  E +  RR +K+LLLG   SGKST +KQM+IIH   F+ +A  E
Sbjct: 9   EKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKE 68

Query: 93  FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQLYVP 152
           ++  I  N +     ++ A   L I +   +     + L A    A    E     L V 
Sbjct: 69  YKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGV- 127

Query: 153 ALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIV 212
            +  LW D G +  FSR SE+ L ++  Y+L++L+RI   +Y P+ +DIL +R  T GIV
Sbjct: 128 -MRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIV 186

Query: 213 EHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVE 272
           E+ F  K++ FKMVDVGGQRS+R+KW  CF+G+T+I+F V  S YD  L ED +T+R+ E
Sbjct: 187 ENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAE 246

Query: 273 SMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLV 332
           S+ +F++I NN  F N S+ILFLNK DLL EK++ + +   FP+++G  +  E+   Y+ 
Sbjct: 247 SLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQ-NTYEEAAVYIQ 305

Query: 333 QCFDRKRRNR-SKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380
           + F+   RN+ +K ++ HFT A DT N++FVF AV D I+Q NLK I L
Sbjct: 306 RQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGL 354


>gi|156104883 guanine nucleotide binding protein (G protein), alpha
           15 (Gq class) [Homo sapiens]
          Length = 374

 Score =  270 bits (691), Expect = 1e-72
 Identities = 141/361 (39%), Positives = 223/361 (61%), Gaps = 18/361 (4%)

Query: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
           E+ A R  ++I+ +L  +++  R  +K+LLLG GESGKSTF+KQMRIIHG  + ++    
Sbjct: 18  EKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKG 77

Query: 93  FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQL-YV 151
           FR  ++ NI    R +++A ++L IP+   E++ H   +M+ +     P +  TF+  Y 
Sbjct: 78  FRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD-----PYKVTTFEKRYA 132

Query: 152 PALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGI 211
            A+  LWRD+GIR  + RR EF L +S  Y+L +L+RI +  Y P+ QD+L +R  T GI
Sbjct: 133 AAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGI 192

Query: 212 VEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLV 271
            E+ F ++K   ++VDVGGQ+S+R+KW  CF+ + +++++ S SEYDQ L E+ + NR+ 
Sbjct: 193 NEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMK 252

Query: 272 ESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL 331
           ES+ +F TI+    F + S+ILFLNK D+L EK+ T  +  +FP F+G     E  +R++
Sbjct: 253 ESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFI 312

Query: 332 VQCFDR------------KRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIM 379
           +  + R            K+  RS+ LF H+T A DT+N+R VF  V+D++L   L +I 
Sbjct: 313 LDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEIN 372

Query: 380 L 380
           L
Sbjct: 373 L 373


>gi|5729850 guanine nucleotide binding protein (G protein), alpha
           inhibiting activity polypeptide 3 [Homo sapiens]
          Length = 354

 Score =  268 bits (685), Expect = 6e-72
 Identities = 145/346 (41%), Positives = 207/346 (59%), Gaps = 5/346 (1%)

Query: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
           ++ A  RS+ ID  L  +     + VK+LLLGAGESGKST +KQM+IIH   + +    +
Sbjct: 9   DKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQ 68

Query: 93  FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQLYVP 152
           ++  ++ N ++    ++ A  +L I +  +        L      AG   E         
Sbjct: 69  YKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVL---AGSAEEGVMTPELAG 125

Query: 153 ALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIV 212
            +  LWRD G++  FSR  E+QL +S  Y+L++LDRI Q NY P++QD+L  R  T GIV
Sbjct: 126 VIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIV 185

Query: 213 EHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVE 272
           E  F  K + FKM DVGGQRS+R+KW  CF+G+T+I+F V+ S+YD VL ED   NR+ E
Sbjct: 186 ETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHE 245

Query: 273 SMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYL- 331
           SM +F++I NNK F   SIILFLNK DL  EK+K   +   +P++ G  +  E+   Y+ 
Sbjct: 246 SMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGS-NTYEEAAAYIQ 304

Query: 332 VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
            Q  D  RR  +K ++ HFT A DT+NV+FVF AV D I++ NLK+
Sbjct: 305 CQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKE 350


>gi|22027522 rod-type transducin alpha subunit [Homo sapiens]
          Length = 350

 Score =  264 bits (674), Expect = 1e-70
 Identities = 146/353 (41%), Positives = 208/353 (58%), Gaps = 9/353 (2%)

Query: 26  GSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF 85
           G+GA   E+     SR+++  L  +     R VK+LLLGAGESGKST +KQM+IIH   +
Sbjct: 2   GAGASAEEKH----SRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGY 57

Query: 86  DQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPA 145
             +  LEF   I+ N L+    +V A   L I +  S  +     LM   +       P 
Sbjct: 58  SLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPK 117

Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
                   +  LW+DSGI+  F R SE+QL +S  Y+L +L+R+    Y P++QD+L +R
Sbjct: 118 EMS---DIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSR 174

Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
             T GI+E  F  K + F+M DVGGQRS+R+KW  CF+G+T I+F+ + S YD VL+ED 
Sbjct: 175 VKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDD 234

Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLE 325
             NR+ ES+++F +I N++ F   SI+LFLNK D+  EK+K   +   FPD+ G P+  E
Sbjct: 235 EVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKIKKAHLSICFPDYDG-PNTYE 293

Query: 326 DVQRYL-VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
           D   Y+ VQ  +   R   K ++ H T A DT+NV+FVF AV D I++ENLKD
Sbjct: 294 DAGNYIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKD 346


>gi|22027520 rod-type transducin alpha subunit [Homo sapiens]
          Length = 350

 Score =  264 bits (674), Expect = 1e-70
 Identities = 146/353 (41%), Positives = 208/353 (58%), Gaps = 9/353 (2%)

Query: 26  GSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF 85
           G+GA   E+     SR+++  L  +     R VK+LLLGAGESGKST +KQM+IIH   +
Sbjct: 2   GAGASAEEKH----SRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGY 57

Query: 86  DQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPA 145
             +  LEF   I+ N L+    +V A   L I +  S  +     LM   +       P 
Sbjct: 58  SLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPK 117

Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
                   +  LW+DSGI+  F R SE+QL +S  Y+L +L+R+    Y P++QD+L +R
Sbjct: 118 EMS---DIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSR 174

Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
             T GI+E  F  K + F+M DVGGQRS+R+KW  CF+G+T I+F+ + S YD VL+ED 
Sbjct: 175 VKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDD 234

Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLE 325
             NR+ ES+++F +I N++ F   SI+LFLNK D+  EK+K   +   FPD+ G P+  E
Sbjct: 235 EVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKIKKAHLSICFPDYDG-PNTYE 293

Query: 326 DVQRYL-VQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
           D   Y+ VQ  +   R   K ++ H T A DT+NV+FVF AV D I++ENLKD
Sbjct: 294 DAGNYIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKD 346


>gi|4504041 guanine nucleotide binding protein (G protein), alpha
           inhibiting activity polypeptide 2 [Homo sapiens]
          Length = 355

 Score =  262 bits (669), Expect = 4e-70
 Identities = 144/350 (41%), Positives = 208/350 (59%), Gaps = 12/350 (3%)

Query: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92
           ++ A  RS+ ID  L  +     R VK+LLLGAGESGKST +KQM+IIH   + ++   +
Sbjct: 9   DKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQ 68

Query: 93  FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAF----ENKAGLPVEPATFQ 148
           +R  ++ N ++    +V A   L I +           L A     E +  LP + +   
Sbjct: 69  YRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSG-- 126

Query: 149 LYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKAT 208
                +  LW D G++  F R  E+QL +S  Y+L++L+RI Q +Y P++QD+L  R  T
Sbjct: 127 ----VIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKT 182

Query: 209 KGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTN 268
            GIVE  F  K + FKM DVGGQRS+R+KW  CF+G+T+I+F V+ S YD VL ED   N
Sbjct: 183 TGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMN 242

Query: 269 RLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQ 328
           R+ ESM +F++I NNK F + SIILFLNK DL  EK+    +   FP++ G  ++ ++  
Sbjct: 243 RMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTG-ANKYDEAA 301

Query: 329 RYLVQCF-DRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKD 377
            Y+   F D  +R  +K ++ HFT A DT+NV+FVF AV D I++ NLKD
Sbjct: 302 SYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKD 351


>gi|117938765 GNAS complex locus isoform g [Homo sapiens]
          Length = 379

 Score =  231 bits (589), Expect = 8e-61
 Identities = 137/370 (37%), Positives = 207/370 (55%), Gaps = 23/370 (6%)

Query: 30  RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKA 89
           R+ E+  R  ++ I+  L ++++  R   ++LLLGAGESGKST +KQMRI+H   F+   
Sbjct: 13  RNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDE 72

Query: 90  LLEFRDTIFDNILKGSRVLVDARDKLGIPWQYS--ENEKHGMFLMAFENKAGLPVEPATF 147
                  I +N+ +    +V A   L  P + +  EN+    ++++  N       P  +
Sbjct: 73  KATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFY 132

Query: 148 QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKA 207
           +       ALW D G+R  + R +E+QL +  +YFLD +D I Q +Y PS QD+L  R  
Sbjct: 133 E----HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVL 188

Query: 208 TKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRT 267
           T GI E  F + K+ F M DVGGQR +R+KW QCF+ +T+I+F+V+SS Y+ V+ ED +T
Sbjct: 189 TSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQT 248

Query: 268 NRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFR------- 318
           NRL E++N+F++I NN+    +S+ILFLNK DLL EKV      I+ +FP+F        
Sbjct: 249 NRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPED 308

Query: 319 GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTENVRFVFHAVKDTI 370
             P   ED +    + F R    R            + HFT A+DTEN+R VF+  +D I
Sbjct: 309 ATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDII 368

Query: 371 LQENLKDIML 380
            + +L+   L
Sbjct: 369 QRMHLRQYEL 378


>gi|18426900 GNAS complex locus GNASS [Homo sapiens]
          Length = 380

 Score =  231 bits (589), Expect = 8e-61
 Identities = 139/372 (37%), Positives = 211/372 (56%), Gaps = 26/372 (6%)

Query: 30  RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREF--DQ 87
           R+ E+  R  ++ I+  L ++++  R   ++LLLGAGESGKST +KQMRI+H   F  D 
Sbjct: 13  RNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDS 72

Query: 88  KALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYS--ENEKHGMFLMAFENKAGLPVEPA 145
           +   + +D I +N+ +    +V A   L  P + +  EN+    ++++  N       P 
Sbjct: 73  EKATKVQD-IKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPE 131

Query: 146 TFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
            ++       ALW D G+R  + R +E+QL +  +YFLD +D I Q +Y PS QD+L  R
Sbjct: 132 FYE----HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCR 187

Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
             T GI E  F + K+ F M DVGGQR +R+KW QCF+ +T+I+F+V+SS Y+ V+ ED 
Sbjct: 188 VLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDN 247

Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFR----- 318
           +TNRL E++N+F++I NN+    +S+ILFLNK DLL EKV      I+ +FP+F      
Sbjct: 248 QTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTP 307

Query: 319 --GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTENVRFVFHAVKD 368
               P   ED +    + F R    R            + HFT A+DTEN+R VF+  +D
Sbjct: 308 EDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRD 367

Query: 369 TILQENLKDIML 380
            I + +L+   L
Sbjct: 368 IIQRMHLRQYEL 379


>gi|33695153 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           1 [Homo sapiens]
          Length = 458

 Score =  228 bits (582), Expect = 5e-60
 Identities = 139/383 (36%), Positives = 217/383 (56%), Gaps = 33/383 (8%)

Query: 22  ERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIH 81
           E R  +  R+A +EAR+ SR ID +L  ++R +++  ++LLLGAGESGKST +KQMRI+H
Sbjct: 84  EEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILH 143

Query: 82  GREFD----QKALLEFRDTIFDNILKGSRVLVDARDKL--GIPWQYSENEKHGMFLMAFE 135
              F+    ++ +L+ R  + D I+     +V A   +   +P    EN+    ++    
Sbjct: 144 VNGFNPEEKKQKILDIRKNVKDAIV----TIVSAMSTIIPPVPLANPENQFRSDYI---- 195

Query: 136 NKAGLPVEPATF-QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNY 194
            K+  P+    + Q +   +  LW D G++  F R +E+QL +  +YFL+ +D +  ++Y
Sbjct: 196 -KSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDY 254

Query: 195 FPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSS 254
            P+ QD+L  R  T GI E  F + K+ F M DVGGQR +R+KW QCF+ +T+I+++ + 
Sbjct: 255 TPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAAC 314

Query: 255 SEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKK 312
           S Y+ V+ ED  TNRL ES+++FE+I NN+    +SIILFLNK D+L EKV      I+ 
Sbjct: 315 SSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIED 374

Query: 313 HFPDFR-------GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTE 357
           +FP++          P   ED +    + F R    R            + HFT A+DTE
Sbjct: 375 YFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTE 434

Query: 358 NVRFVFHAVKDTILQENLKDIML 380
           N+R VF+  +D I + +LK   L
Sbjct: 435 NIRRVFNDCRDIIQRMHLKQYEL 457


>gi|4504047 GNAS complex locus GNASL [Homo sapiens]
          Length = 394

 Score =  227 bits (579), Expect = 1e-59
 Identities = 141/385 (36%), Positives = 211/385 (54%), Gaps = 38/385 (9%)

Query: 30  RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIH-------G 82
           R+ E+  R  ++ I+  L ++++  R   ++LLLGAGESGKST +KQMRI+H       G
Sbjct: 13  RNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEG 72

Query: 83  REFDQKALLEFRD--------TIFDNILKGSRVLVDARDKLGIPWQYS--ENEKHGMFLM 132
            E D +A     D         I +N+ +    +V A   L  P + +  EN+    +++
Sbjct: 73  GEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYIL 132

Query: 133 AFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQL 192
           +  N       P  ++       ALW D G+R  + R +E+QL +  +YFLD +D I Q 
Sbjct: 133 SVMNVPDFDFPPEFYE----HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQA 188

Query: 193 NYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMV 252
           +Y PS QD+L  R  T GI E  F + K+ F M DVGGQR +R+KW QCF+ +T+I+F+V
Sbjct: 189 DYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVV 248

Query: 253 SSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSI 310
           +SS Y+ V+ ED +TNRL E++N+F++I NN+    +S+ILFLNK DLL EKV      I
Sbjct: 249 ASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKI 308

Query: 311 KKHFPDFR-------GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAID 355
           + +FP+F          P   ED +    + F R    R            + HFT A+D
Sbjct: 309 EDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVD 368

Query: 356 TENVRFVFHAVKDTILQENLKDIML 380
           TEN+R VF+  +D I + +L+   L
Sbjct: 369 TENIRRVFNDCRDIIQRMHLRQYEL 393


>gi|117938762 GNAS complex locus isoform f [Homo sapiens]
          Length = 395

 Score =  227 bits (578), Expect = 2e-59
 Identities = 141/386 (36%), Positives = 211/386 (54%), Gaps = 39/386 (10%)

Query: 30  RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIH-------G 82
           R+ E+  R  ++ I+  L ++++  R   ++LLLGAGESGKST +KQMRI+H       G
Sbjct: 13  RNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEG 72

Query: 83  REFDQKALLEFRD---------TIFDNILKGSRVLVDARDKLGIPWQYS--ENEKHGMFL 131
            E D +A     D          I +N+ +    +V A   L  P + +  EN+    ++
Sbjct: 73  GEEDPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYI 132

Query: 132 MAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQ 191
           ++  N       P  ++       ALW D G+R  + R +E+QL +  +YFLD +D I Q
Sbjct: 133 LSVMNVPDFDFPPEFYE----HAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQ 188

Query: 192 LNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFM 251
            +Y PS QD+L  R  T GI E  F + K+ F M DVGGQR +R+KW QCF+ +T+I+F+
Sbjct: 189 ADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFV 248

Query: 252 VSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VS 309
           V+SS Y+ V+ ED +TNRL E++N+F++I NN+    +S+ILFLNK DLL EKV      
Sbjct: 249 VASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSK 308

Query: 310 IKKHFPDFR-------GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAI 354
           I+ +FP+F          P   ED +    + F R    R            + HFT A+
Sbjct: 309 IEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAV 368

Query: 355 DTENVRFVFHAVKDTILQENLKDIML 380
           DTEN+R VF+  +D I + +L+   L
Sbjct: 369 DTENIRRVFNDCRDIIQRMHLRQYEL 394


>gi|117938759 GNAS complex locus XLas [Homo sapiens]
          Length = 1037

 Score =  226 bits (575), Expect = 3e-59
 Identities = 147/409 (35%), Positives = 217/409 (53%), Gaps = 38/409 (9%)

Query: 6    RTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGA 65
            R+L    +P      + R+     R  +R  ++RS+ ID  L  E+       ++LLLGA
Sbjct: 632  RSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGA 691

Query: 66   GESGKSTFLKQMRIIH-------GREFDQKALLEFRD--------TIFDNILKGSRVLVD 110
            GESGKST +KQMRI+H       G E D +A     D         I +N+ +    +V 
Sbjct: 692  GESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVA 751

Query: 111  ARDKLGIPWQYS--ENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFS 168
            A   L  P + +  EN+    ++++  N       P  ++       ALW D G+R  + 
Sbjct: 752  AMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYE----HAKALWEDEGVRACYE 807

Query: 169  RRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDV 228
            R +E+QL +  +YFLD +D I Q +Y PS QD+L  R  T GI E  F + K+ F M DV
Sbjct: 808  RSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDV 867

Query: 229  GGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFN 288
            GGQR +R+KW QCF+ +T+I+F+V+SS Y+ V+ ED +TNRL E++N+F++I NN+    
Sbjct: 868  GGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRT 927

Query: 289  VSIILFLNKMDLLVEKVKT--VSIKKHFPDFR-------GDPHRLEDVQRYLVQCFDRKR 339
            +S+ILFLNK DLL EKV      I+ +FP+F          P   ED +    + F R  
Sbjct: 928  ISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDE 987

Query: 340  RNRSKP--------LFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380
              R            + HFT A+DTEN+R VF+  +D I + +L+   L
Sbjct: 988  FLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYEL 1036


>gi|4504043 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           2 [Homo sapiens]
          Length = 381

 Score =  219 bits (558), Expect = 3e-57
 Identities = 134/372 (36%), Positives = 208/372 (55%), Gaps = 33/372 (8%)

Query: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFD----QK 88
           E+E R  ++ I+  L +ER A +   ++LLLGAGESGKST +KQMRI+H   F+    ++
Sbjct: 18  EKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQ 77

Query: 89  ALLEFRDTIFDNILKGSRVLVDARDKL--GIPWQYSENEKHGMFLMAFENKAGLPVEPAT 146
            +L+ R  + D I+     +V A   +   +P    EN+    ++     K+  P+    
Sbjct: 78  KILDIRKNVKDAIV----TIVSAMSTIIPPVPLANPENQFRSDYI-----KSIAPITDFE 128

Query: 147 F-QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
           + Q +   +  LW D G++  F R +E+QL +  +YFL+ +D +  ++Y P+ QD+L  R
Sbjct: 129 YSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCR 188

Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
             T GI E  F + K+ F M DVGGQR +R+KW QCF+ +T+I+++ + S Y+ V+ ED 
Sbjct: 189 VLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDN 248

Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFR----- 318
            TNRL ES+++FE+I NN+    +SIILFLNK D+L EKV      I+ +FP++      
Sbjct: 249 NTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVP 308

Query: 319 --GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTENVRFVFHAVKD 368
               P   ED +    + F R    R            + HFT A+DTEN+R VF+  +D
Sbjct: 309 EDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRD 368

Query: 369 TILQENLKDIML 380
            I + +LK   L
Sbjct: 369 IIQRMHLKQYEL 380


>gi|215272301 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           2 [Homo sapiens]
          Length = 381

 Score =  219 bits (558), Expect = 3e-57
 Identities = 134/372 (36%), Positives = 208/372 (55%), Gaps = 33/372 (8%)

Query: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFD----QK 88
           E+E R  ++ I+  L +ER A +   ++LLLGAGESGKST +KQMRI+H   F+    ++
Sbjct: 18  EKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQ 77

Query: 89  ALLEFRDTIFDNILKGSRVLVDARDKL--GIPWQYSENEKHGMFLMAFENKAGLPVEPAT 146
            +L+ R  + D I+     +V A   +   +P    EN+    ++     K+  P+    
Sbjct: 78  KILDIRKNVKDAIV----TIVSAMSTIIPPVPLANPENQFRSDYI-----KSIAPITDFE 128

Query: 147 F-QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLAR 205
           + Q +   +  LW D G++  F R +E+QL +  +YFL+ +D +  ++Y P+ QD+L  R
Sbjct: 129 YSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCR 188

Query: 206 KATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDR 265
             T GI E  F + K+ F M DVGGQR +R+KW QCF+ +T+I+++ + S Y+ V+ ED 
Sbjct: 189 VLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDN 248

Query: 266 RTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKT--VSIKKHFPDFR----- 318
            TNRL ES+++FE+I NN+    +SIILFLNK D+L EKV      I+ +FP++      
Sbjct: 249 NTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVP 308

Query: 319 --GDPHRLEDVQRYLVQCFDRKRRNRSKP--------LFHHFTTAIDTENVRFVFHAVKD 368
               P   ED +    + F R    R            + HFT A+DTEN+R VF+  +D
Sbjct: 309 EDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRD 368

Query: 369 TILQENLKDIML 380
            I + +LK   L
Sbjct: 369 IIQRMHLKQYEL 380


>gi|4502211 ADP-ribosylation factor 6 [Homo sapiens]
          Length = 175

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 10/93 (10%)

Query: 208 TKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRT 267
           T G        K + F + DVGGQ   R  W   + G   ++F+V  ++ D         
Sbjct: 44  TVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD--------- 94

Query: 268 NRLVESMNIFETIVNNKLFFNVSIILFLNKMDL 300
            R+ E+      I+N++   +  I++F NK DL
Sbjct: 95  -RIDEARQELHRIINDREMRDAIILIFANKQDL 126


>gi|7705827 SAR1a gene homolog 2 [Homo sapiens]
          Length = 198

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 31/124 (25%), Positives = 54/124 (43%), Gaps = 12/124 (9%)

Query: 176 GESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQR 235
           G+ V   LDN  +   L+    K D L     T      +  I  + F   D+GG    R
Sbjct: 26  GKLVFLGLDNAGKTTLLHML--KDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQAR 83

Query: 236 QKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFL 295
           + W      I  I+F+V  ++++          RL+ES    ++++ ++   NV I++  
Sbjct: 84  RVWKNYLPAINGIVFLVDCADHE----------RLLESKEELDSLMTDETIANVPILILG 133

Query: 296 NKMD 299
           NK+D
Sbjct: 134 NKID 137


>gi|75709204 SAR1a gene homolog 2 [Homo sapiens]
          Length = 198

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 31/124 (25%), Positives = 54/124 (43%), Gaps = 12/124 (9%)

Query: 176 GESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQR 235
           G+ V   LDN  +   L+    K D L     T      +  I  + F   D+GG    R
Sbjct: 26  GKLVFLGLDNAGKTTLLHML--KDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQAR 83

Query: 236 QKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFL 295
           + W      I  I+F+V  ++++          RL+ES    ++++ ++   NV I++  
Sbjct: 84  RVWKNYLPAINGIVFLVDCADHE----------RLLESKEELDSLMTDETIANVPILILG 133

Query: 296 NKMD 299
           NK+D
Sbjct: 134 NKID 137


>gi|217416369 SAR1a gene homolog 1 [Homo sapiens]
          Length = 198

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 12/124 (9%)

Query: 176 GESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQR 235
           G+ V   LDN  +   L+    K D L     T      +  I  + F   D+GG    R
Sbjct: 26  GKLVFLGLDNAGKTTLLHML--KDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQAR 83

Query: 236 QKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFL 295
           + W      I  I+F+V  +++          +RLVES      ++ ++   NV I++  
Sbjct: 84  RVWKNYLPAINGIVFLVDCADH----------SRLVESKVELNALMTDETISNVPILILG 133

Query: 296 NKMD 299
           NK+D
Sbjct: 134 NKID 137


>gi|9910542 SAR1a gene homolog 1 [Homo sapiens]
          Length = 198

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 12/124 (9%)

Query: 176 GESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQR 235
           G+ V   LDN  +   L+    K D L     T      +  I  + F   D+GG    R
Sbjct: 26  GKLVFLGLDNAGKTTLLHML--KDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQAR 83

Query: 236 QKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFL 295
           + W      I  I+F+V  +++          +RLVES      ++ ++   NV I++  
Sbjct: 84  RVWKNYLPAINGIVFLVDCADH----------SRLVESKVELNALMTDETISNVPILILG 133

Query: 296 NKMD 299
           NK+D
Sbjct: 134 NKID 137


>gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma
           [Homo sapiens]
          Length = 546

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 33/144 (22%), Positives = 60/144 (41%), Gaps = 13/144 (9%)

Query: 160 DSGIREAFSRRSEFQLGES--VKYFLDNLDRIGQLNY-FPSKQDILLARKATKGIVEHDF 216
           D+ I   F++ +   +G    ++     LD  G+    F  KQD  +    T G      
Sbjct: 384 DASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETV 443

Query: 217 VIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNI 276
             K + F + DVGG+   R  W   +    +++F+V SS  D          R+ E+ + 
Sbjct: 444 EYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRD----------RISEAHSE 493

Query: 277 FETIVNNKLFFNVSIILFLNKMDL 300
              ++  K   +  +++F NK D+
Sbjct: 494 LAKLLTEKELRDALLLIFANKQDV 517


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.140    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,303,583
Number of Sequences: 37866
Number of extensions: 503874
Number of successful extensions: 2168
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2061
Number of HSP's gapped (non-prelim): 90
length of query: 381
length of database: 18,247,518
effective HSP length: 104
effective length of query: 277
effective length of database: 14,309,454
effective search space: 3963718758
effective search space used: 3963718758
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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