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Search of human proteins with 41871960
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41871960 kinesin-like 8 isoform b [Homo sapiens]
(637 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41871960 kinesin-like 8 isoform b [Homo sapiens] 1258 0.0
gi|41871955 kinesin-like 8 isoform a [Homo sapiens] 1222 0.0
gi|41871946 kinesin-like 8 isoform a [Homo sapiens] 1222 0.0
gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens] 811 0.0
gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens] 811 0.0
gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens] 811 0.0
gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens] 808 0.0
gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens] 768 0.0
gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens] 766 0.0
gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens] 647 0.0
gi|19923891 kinesin-like 8 isoform c [Homo sapiens] 577 e-164
gi|91825557 kinesin light chain 3 [Homo sapiens] 520 e-147
gi|34304360 nephrocystin 3 [Homo sapiens] 147 4e-35
gi|87162455 hypothetical protein LOC23277 [Homo sapiens] 62 2e-09
gi|18104962 amyloid beta precursor protein-binding protein 2 [Ho... 55 2e-07
gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens] 54 3e-07
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 51 3e-06
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 51 3e-06
gi|22749211 transmembrane and tetratricopeptide repeat containin... 50 5e-06
gi|83415184 transmembrane and tetratricopeptide repeat containin... 48 3e-05
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 47 4e-05
gi|17864094 feminization 1 homolog a [Homo sapiens] 47 5e-05
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 47 7e-05
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 45 2e-04
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 45 2e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 44 5e-04
gi|238908495 similar to pleckstrin homology domain protein (5V32... 44 6e-04
gi|81295809 pericentrin [Homo sapiens] 43 8e-04
gi|145699105 connexin40.1 [Homo sapiens] 43 8e-04
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 42 0.002
>gi|41871960 kinesin-like 8 isoform b [Homo sapiens]
Length = 637
Score = 1258 bits (3255), Expect = 0.0
Identities = 637/637 (100%), Positives = 637/637 (100%)
Query: 1 MEVTGFGVTRPGKVPQARMSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQA 60
MEVTGFGVTRPGKVPQARMSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQA
Sbjct: 1 MEVTGFGVTRPGKVPQARMSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQA 60
Query: 61 VLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEK 120
VLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEK
Sbjct: 61 VLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEK 120
Query: 121 QKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHT 180
QKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHT
Sbjct: 121 QKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHT 180
Query: 181 SEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYA 240
SEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYA
Sbjct: 181 SEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYA 240
Query: 241 AQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI 300
AQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI
Sbjct: 241 AQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI 300
Query: 301 RESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNN 360
RESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNN
Sbjct: 301 RESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNN 360
Query: 361 LALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLY 420
LALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLY
Sbjct: 361 LALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLY 420
Query: 421 KEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPT 480
KEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPT
Sbjct: 421 KEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPT 480
Query: 481 VNTTLRNLGALYRRQGKLEAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEG 540
VNTTLRNLGALYRRQGKLEAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEG
Sbjct: 481 VNTTLRNLGALYRRQGKLEAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEG 540
Query: 541 PGDSVKFEGGEDASVAVEWSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPRPSS 600
PGDSVKFEGGEDASVAVEWSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPRPSS
Sbjct: 541 PGDSVKFEGGEDASVAVEWSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPRPSS 600
Query: 601 SNMKRAASLNYLNQPSAAPLQVSRGLSASTMDLSSSS 637
SNMKRAASLNYLNQPSAAPLQVSRGLSASTMDLSSSS
Sbjct: 601 SNMKRAASLNYLNQPSAAPLQVSRGLSASTMDLSSSS 637
>gi|41871955 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 1222 bits (3161), Expect = 0.0
Identities = 619/619 (100%), Positives = 619/619 (100%)
Query: 19 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 78
MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE
Sbjct: 1 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 60
Query: 79 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 138
EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR
Sbjct: 61 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 120
Query: 139 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 198
DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP
Sbjct: 121 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 180
Query: 199 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 258
NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED
Sbjct: 181 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 240
Query: 259 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNN 318
LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNN
Sbjct: 241 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNN 300
Query: 319 LAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYY 378
LAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYY
Sbjct: 301 LAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYY 360
Query: 379 QRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDD 438
QRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDD
Sbjct: 361 QRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDD 420
Query: 439 HKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKL 498
HKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKL
Sbjct: 421 HKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKL 480
Query: 499 EAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGGEDASVAVE 558
EAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGGEDASVAVE
Sbjct: 481 EAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGGEDASVAVE 540
Query: 559 WSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPRPSSSNMKRAASLNYLNQPSAA 618
WSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPRPSSSNMKRAASLNYLNQPSAA
Sbjct: 541 WSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPRPSSSNMKRAASLNYLNQPSAA 600
Query: 619 PLQVSRGLSASTMDLSSSS 637
PLQVSRGLSASTMDLSSSS
Sbjct: 601 PLQVSRGLSASTMDLSSSS 619
>gi|41871946 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 1222 bits (3161), Expect = 0.0
Identities = 619/619 (100%), Positives = 619/619 (100%)
Query: 19 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 78
MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE
Sbjct: 1 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 60
Query: 79 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 138
EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR
Sbjct: 61 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 120
Query: 139 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 198
DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP
Sbjct: 121 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 180
Query: 199 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 258
NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED
Sbjct: 181 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 240
Query: 259 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNN 318
LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNN
Sbjct: 241 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNN 300
Query: 319 LAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYY 378
LAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYY
Sbjct: 301 LAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYY 360
Query: 379 QRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDD 438
QRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDD
Sbjct: 361 QRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDD 420
Query: 439 HKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKL 498
HKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKL
Sbjct: 421 HKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKL 480
Query: 499 EAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGGEDASVAVE 558
EAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGGEDASVAVE
Sbjct: 481 EAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGGEDASVAVE 540
Query: 559 WSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPRPSSSNMKRAASLNYLNQPSAA 618
WSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPRPSSSNMKRAASLNYLNQPSAA
Sbjct: 541 WSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPRPSSSNMKRAASLNYLNQPSAA 600
Query: 619 PLQVSRGLSASTMDLSSSS 637
PLQVSRGLSASTMDLSSSS
Sbjct: 601 PLQVSRGLSASTMDLSSSS 619
>gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 811 bits (2095), Expect = 0.0
Identities = 432/622 (69%), Positives = 486/622 (78%), Gaps = 24/622 (3%)
Query: 30 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 89
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
Query: 90 RRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQ 149
RRS+E IELGL EAQV+LAL+SHL VESEKQKLRAQVRRL QENQWLR+ELAGTQQ+LQ
Sbjct: 62 RRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQ 121
Query: 150 RSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGL 209
RSEQAVAQLEEEK+HL F+ Q+R+ DED +EEK GD KD+LDDLFPNE+E+ P+
Sbjct: 122 RSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEK-GDVPKDTLDDLFPNEDEQSPAP-- 178
Query: 210 SRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD 269
S G G + Q GGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPD
Sbjct: 179 SPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 238
Query: 270 VATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKY 329
VATMLNILALVYRDQNKYKEAAHLLNDAL+IRE TLG DHPAVAATLNNLAVLYGKRGKY
Sbjct: 239 VATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKY 298
Query: 330 KEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQL 389
KEAEPLC+RALEIREKVLG HPDVAKQL+NLALLCQNQGK E VE YY+RAL IY +L
Sbjct: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRL 358
Query: 390 GPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEER 449
GPD+PNVA+TKNNLASCYLKQGKY +AETLYKEILTRAH +EFGSV+ D+KPIWMHAEER
Sbjct: 359 GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEER 418
Query: 450 EEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECAL 509
EE R PY EYG WYKACKV SPTVNTTLR+LGALYRRQGKLEAA TLE+CA
Sbjct: 419 EESKDKR--RDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCAS 476
Query: 510 RSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGG------EDASVAVEWSGDG 563
R+R+QG DP SQTKV ELL + GRR + D G ED EW+GDG
Sbjct: 477 RNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDG 536
Query: 564 SGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPR-PSSSNMKRAASLNYLN-------QP 615
SG+L+RSGS GK+RD LRRSSE+LV+KLQG P+ P + MKRA+SLN+LN QP
Sbjct: 537 SGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQP 596
Query: 616 SAAPLQVSRGLSASTMDLSSSS 637
L SR LS+S+MDLS S
Sbjct: 597 GGTGLSDSRTLSSSSMDLSRRS 618
>gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 811 bits (2095), Expect = 0.0
Identities = 432/622 (69%), Positives = 486/622 (78%), Gaps = 24/622 (3%)
Query: 30 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 89
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
Query: 90 RRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQ 149
RRS+E IELGL EAQV+LAL+SHL VESEKQKLRAQVRRL QENQWLR+ELAGTQQ+LQ
Sbjct: 62 RRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQ 121
Query: 150 RSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGL 209
RSEQAVAQLEEEK+HL F+ Q+R+ DED +EEK GD KD+LDDLFPNE+E+ P+
Sbjct: 122 RSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEK-GDVPKDTLDDLFPNEDEQSPAP-- 178
Query: 210 SRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD 269
S G G + Q GGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPD
Sbjct: 179 SPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 238
Query: 270 VATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKY 329
VATMLNILALVYRDQNKYKEAAHLLNDAL+IRE TLG DHPAVAATLNNLAVLYGKRGKY
Sbjct: 239 VATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKY 298
Query: 330 KEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQL 389
KEAEPLC+RALEIREKVLG HPDVAKQL+NLALLCQNQGK E VE YY+RAL IY +L
Sbjct: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRL 358
Query: 390 GPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEER 449
GPD+PNVA+TKNNLASCYLKQGKY +AETLYKEILTRAH +EFGSV+ D+KPIWMHAEER
Sbjct: 359 GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEER 418
Query: 450 EEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECAL 509
EE R PY EYG WYKACKV SPTVNTTLR+LGALYRRQGKLEAA TLE+CA
Sbjct: 419 EESKDKR--RDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCAS 476
Query: 510 RSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGG------EDASVAVEWSGDG 563
R+R+QG DP SQTKV ELL + GRR + D G ED EW+GDG
Sbjct: 477 RNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDG 536
Query: 564 SGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPR-PSSSNMKRAASLNYLN-------QP 615
SG+L+RSGS GK+RD LRRSSE+LV+KLQG P+ P + MKRA+SLN+LN QP
Sbjct: 537 SGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQP 596
Query: 616 SAAPLQVSRGLSASTMDLSSSS 637
L SR LS+S+MDLS S
Sbjct: 597 GGTGLSDSRTLSSSSMDLSRRS 618
>gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 811 bits (2095), Expect = 0.0
Identities = 432/622 (69%), Positives = 486/622 (78%), Gaps = 24/622 (3%)
Query: 30 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 89
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
Query: 90 RRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQ 149
RRS+E IELGL EAQV+LAL+SHL VESEKQKLRAQVRRL QENQWLR+ELAGTQQ+LQ
Sbjct: 62 RRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQ 121
Query: 150 RSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGL 209
RSEQAVAQLEEEK+HL F+ Q+R+ DED +EEK GD KD+LDDLFPNE+E+ P+
Sbjct: 122 RSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEK-GDVPKDTLDDLFPNEDEQSPAP-- 178
Query: 210 SRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD 269
S G G + Q GGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPD
Sbjct: 179 SPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 238
Query: 270 VATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKY 329
VATMLNILALVYRDQNKYKEAAHLLNDAL+IRE TLG DHPAVAATLNNLAVLYGKRGKY
Sbjct: 239 VATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKY 298
Query: 330 KEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQL 389
KEAEPLC+RALEIREKVLG HPDVAKQL+NLALLCQNQGK E VE YY+RAL IY +L
Sbjct: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRL 358
Query: 390 GPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEER 449
GPD+PNVA+TKNNLASCYLKQGKY +AETLYKEILTRAH +EFGSV+ D+KPIWMHAEER
Sbjct: 359 GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEER 418
Query: 450 EEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECAL 509
EE R PY EYG WYKACKV SPTVNTTLR+LGALYRRQGKLEAA TLE+CA
Sbjct: 419 EESKDKR--RDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCAS 476
Query: 510 RSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGG------EDASVAVEWSGDG 563
R+R+QG DP SQTKV ELL + GRR + D G ED EW+GDG
Sbjct: 477 RNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDG 536
Query: 564 SGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPR-PSSSNMKRAASLNYLN-------QP 615
SG+L+RSGS GK+RD LRRSSE+LV+KLQG P+ P + MKRA+SLN+LN QP
Sbjct: 537 SGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQP 596
Query: 616 SAAPLQVSRGLSASTMDLSSSS 637
L SR LS+S+MDLS S
Sbjct: 597 GGTGLSDSRTLSSSSMDLSRRS 618
>gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
Length = 618
Score = 808 bits (2088), Expect = 0.0
Identities = 414/600 (69%), Positives = 497/600 (82%), Gaps = 16/600 (2%)
Query: 34 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSM 93
+L+Q+EI+ T+ V QGLEAL++EH ++LQSL +T++CL++ E LV EK+ +R+S+
Sbjct: 18 KLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD-ESNLVEEKSNMIRKSL 76
Query: 94 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQ 153
E +ELGLSEAQVM+AL++HL+ VESEKQKLRAQVRRLCQENQWLRDELA TQQ+LQ+SEQ
Sbjct: 77 EMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQ 136
Query: 154 AVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR-- 211
+VAQLEEEKKHLEF+ QL++YD+D SE+K+ D+TK+ LDDLFPN+E+ DP G+ +
Sbjct: 137 SVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDED-DPGQGIQQQH 195
Query: 212 GQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVA 271
A AAQQGGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPDVA
Sbjct: 196 SSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 255
Query: 272 TMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKE 331
TMLNILALVYRDQNKYK+AA+LLNDAL+IRE TLG DHPAVAATLNNLAVLYGKRGKYKE
Sbjct: 256 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 315
Query: 332 AEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGP 391
AEPLC+RALEIREKVLG +HPDVAKQLNNLALLCQNQGKYE VE YYQRAL IY+ +LGP
Sbjct: 316 AEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGP 375
Query: 392 DNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREE 451
D+PNVA+TKNNLASCYLKQGK+ +AETLYKEILTRAH +EFGSVDD++KPIWMHAEEREE
Sbjct: 376 DDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREE 435
Query: 452 MSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECALRS 511
+ + GT + EYGGWYKACKV SPTV TTL+NLGALYRRQGK EAAETLEE A+RS
Sbjct: 436 CKGKQ--KDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRS 493
Query: 512 RRQGTDPISQTKVAELLGESDG---RRTSQEGPGDSVKFE----GGEDASVAVEWSGDGS 564
R+QG D + + +VAE+L + + RR+ + D VK+E GGE+ S++VEW+GDG+
Sbjct: 494 RKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGEEVSMSVEWNGDGT 553
Query: 565 GTLQRSGSLGKIRDVLRRSSELLVRKLQG---TEPRPSSSNMKRAASLNYLNQPSAAPLQ 621
G+L+RSGS K+R +RRSSE LVRKL+G E P + A L N S++ L+
Sbjct: 554 GSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRESEPKNPGASLAEPLFVENDSSSSGLE 613
>gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]
Length = 573
Score = 768 bits (1983), Expect = 0.0
Identities = 388/541 (71%), Positives = 461/541 (85%), Gaps = 13/541 (2%)
Query: 34 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSM 93
+L+Q+EI+ T+ V QGLEAL++EH ++LQSL +T++CL++ E LV EK+ +R+S+
Sbjct: 18 KLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD-ESNLVEEKSNMIRKSL 76
Query: 94 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQ 153
E +ELGLSEAQVM+AL++HL+ VESEKQKLRAQVRRLCQENQWLRDELA TQQ+LQ+SEQ
Sbjct: 77 EMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQ 136
Query: 154 AVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR-- 211
+VAQLEEEKKHLEF+ QL++YD+D SE+K+ D+TK+ LDDLFPN+E+ DP G+ +
Sbjct: 137 SVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDED-DPGQGIQQQH 195
Query: 212 GQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVA 271
A AAQQGGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPDVA
Sbjct: 196 SSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 255
Query: 272 TMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKE 331
TMLNILALVYRDQNKYK+AA+LLNDAL+IRE TLG DHPAVAATLNNLAVLYGKRGKYKE
Sbjct: 256 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 315
Query: 332 AEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGP 391
AEPLC+RALEIREKVLG +HPDVAKQLNNLALLCQNQGKYE VE YYQRAL IY+ +LGP
Sbjct: 316 AEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGP 375
Query: 392 DNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREE 451
D+PNVA+TKNNLASCYLKQGK+ +AETLYKEILTRAH +EFGSVDD++KPIWMHAEEREE
Sbjct: 376 DDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREE 435
Query: 452 MSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECALRS 511
+ + GT + EYGGWYKACKV SPTV TTL+NLGALYRRQGK EAAETLEE A+RS
Sbjct: 436 CKGKQ--KDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRS 493
Query: 512 RRQGTDPISQTKVAELLGESDG---RRTSQEGPGDSVKFE----GGEDASVAVEWSGDGS 564
R+QG D + + +VAE+L + + RR+ + D VK+E GGE+ S++VEW+G S
Sbjct: 494 RKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGEEVSMSVEWNGGVS 553
Query: 565 G 565
G
Sbjct: 554 G 554
>gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens]
Length = 560
Score = 766 bits (1977), Expect = 0.0
Identities = 386/537 (71%), Positives = 459/537 (85%), Gaps = 13/537 (2%)
Query: 34 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSM 93
+L+Q+EI+ T+ V QGLEAL++EH ++LQSL +T++CL++ E LV EK+ +R+S+
Sbjct: 18 KLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD-ESNLVEEKSNMIRKSL 76
Query: 94 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQ 153
E +ELGLSEAQVM+AL++HL+ VESEKQKLRAQVRRLCQENQWLRDELA TQQ+LQ+SEQ
Sbjct: 77 EMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQ 136
Query: 154 AVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR-- 211
+VAQLEEEKKHLEF+ QL++YD+D SE+K+ D+TK+ LDDLFPN+E+ DP G+ +
Sbjct: 137 SVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDED-DPGQGIQQQH 195
Query: 212 GQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVA 271
A AAQQGGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPDVA
Sbjct: 196 SSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 255
Query: 272 TMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKE 331
TMLNILALVYRDQNKYK+AA+LLNDAL+IRE TLG DHPAVAATLNNLAVLYGKRGKYKE
Sbjct: 256 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 315
Query: 332 AEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGP 391
AEPLC+RALEIREKVLG +HPDVAKQLNNLALLCQNQGKYE VE YYQRAL IY+ +LGP
Sbjct: 316 AEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGP 375
Query: 392 DNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREE 451
D+PNVA+TKNNLASCYLKQGK+ +AETLYKEILTRAH +EFGSVDD++KPIWMHAEEREE
Sbjct: 376 DDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREE 435
Query: 452 MSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECALRS 511
+ + GT + EYGGWYKACKV SPTV TTL+NLGALYRRQGK EAAETLEE A+RS
Sbjct: 436 CKGKQ--KDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRS 493
Query: 512 RRQGTDPISQTKVAELLGESDG---RRTSQEGPGDSVKFE----GGEDASVAVEWSG 561
R+QG D + + +VAE+L + + RR+ + D VK+E GGE+ S++VEW+G
Sbjct: 494 RKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGEEVSMSVEWNG 550
>gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens]
Length = 545
Score = 647 bits (1670), Expect = 0.0
Identities = 336/471 (71%), Positives = 376/471 (79%), Gaps = 18/471 (3%)
Query: 181 SEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYA 240
++E++GD KD+LDDLFPNE+E+ P+ S G G + Q GGYEIPARLRTLHNLVIQYA
Sbjct: 75 AQEEKGDVPKDTLDDLFPNEDEQSPAP--SPGGGDVSGQHGGYEIPARLRTLHNLVIQYA 132
Query: 241 AQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI 300
+QGRYEVAVPLCKQALEDLE+TSG HPDVATMLNILALVYRDQNKYKEAAHLLNDAL+I
Sbjct: 133 SQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI 192
Query: 301 RESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNN 360
RE TLG DHPAVAATLNNLAVLYGKRGKYKEAEPLC+RALEIREKVLG HPDVAKQL+N
Sbjct: 193 REKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSN 252
Query: 361 LALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLY 420
LALLCQNQGK E VE YY+RAL IY +LGPD+PNVA+TKNNLASCYLKQGKY +AETLY
Sbjct: 253 LALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLY 312
Query: 421 KEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPT 480
KEILTRAH +EFGSV+ D+KPIWMHAEEREE R PY EYG WYKACKV SPT
Sbjct: 313 KEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKR--RDSAPYGEYGSWYKACKVDSPT 370
Query: 481 VNTTLRNLGALYRRQGKLEAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEG 540
VNTTLR+LGALYRRQGKLEAA TLE+CA R+R+QG DP SQTKV ELL + GRR +
Sbjct: 371 VNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRS 430
Query: 541 PGDSVKFEGG------EDASVAVEWSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGT 594
D G ED EW+GDGSG+L+RSGS GK+RD LRRSSE+LV+KLQG
Sbjct: 431 SRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGG 490
Query: 595 EPR-PSSSNMKRAASLNYLN-------QPSAAPLQVSRGLSASTMDLSSSS 637
P+ P + MKRA+SLN+LN QP L SR LS+S+MDLS S
Sbjct: 491 TPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRS 541
Score = 143 bits (360), Expect = 6e-34
Identities = 132/408 (32%), Positives = 194/408 (47%), Gaps = 38/408 (9%)
Query: 30 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 89
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
Query: 90 RRSMENIELGLSEAQ-----VMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGT 144
RRS+E IELGL EAQ V L E E+ + + + G
Sbjct: 62 RRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPS------PGGGDVSGQHGGY 115
Query: 145 Q--QRLQRSEQAVAQLEEEKKHLEFLGQLRQYDED-GHTSEEKEGDATK--DSLDDLFPN 199
+ RL+ V Q + ++ + +Q ED TS D + L ++ +
Sbjct: 116 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD 175
Query: 200 EEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDL 259
+ + + L A + G + PA TL+NL + Y +G+Y+ A PLCK+ALE
Sbjct: 176 QNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIR 235
Query: 260 ERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNL 319
E+ G+ HPDVA L+ LAL+ ++Q K +E + AL I + LGPD P VA T NNL
Sbjct: 236 EKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNL 295
Query: 320 AVLYGKRGKYKEAEPLCQRAL-EIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYY 378
A Y K+GKY++AE L + L EK G+ + D N + + + E+ ++
Sbjct: 296 ASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGD------NKPIWMHAEEREESKDK-- 347
Query: 379 QRALAIYEGQLGP-------DNPNVARTKNNLASCYLKQGKYAEAETL 419
+R A Y G+ G D+P V T +L + Y +QGK A TL
Sbjct: 348 RRDSAPY-GEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTL 394
>gi|19923891 kinesin-like 8 isoform c [Homo sapiens]
Length = 315
Score = 577 bits (1487), Expect = e-164
Identities = 294/295 (99%), Positives = 295/295 (100%)
Query: 19 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 78
MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE
Sbjct: 1 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 60
Query: 79 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 138
EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR
Sbjct: 61 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 120
Query: 139 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 198
DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP
Sbjct: 121 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 180
Query: 199 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 258
NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED
Sbjct: 181 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 240
Query: 259 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVA 313
LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAV+
Sbjct: 241 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
Score = 82.0 bits (201), Expect = 2e-15
Identities = 42/92 (45%), Positives = 58/92 (63%)
Query: 306 GPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLC 365
G + PA TL+NL + Y +G+Y+ A PLC++ALE E+ G HPDVA LN LAL+
Sbjct: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
Query: 366 QNQGKYEAVERYYQRALAIYEGQLGPDNPNVA 397
++Q KY+ AL+I E LGPD+P V+
Sbjct: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/78 (34%), Positives = 37/78 (47%)
Query: 348 GTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCY 407
G P + L+NL + QG+YE ++AL E G +P+VA N LA Y
Sbjct: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
Query: 408 LKQGKYAEAETLYKEILT 425
Q KY EA L + L+
Sbjct: 264 RDQNKYKEAAHLLNDALS 281
>gi|91825557 kinesin light chain 3 [Homo sapiens]
Length = 504
Score = 520 bits (1338), Expect = e-147
Identities = 275/393 (69%), Positives = 315/393 (80%), Gaps = 9/393 (2%)
Query: 34 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGL--VHEKARQLRR 91
RLS EE++ TR V QGLEALR+EH + L+ E L G GL + EK + +
Sbjct: 17 RLSPEELVRQTRQVVQGLEALRAEHHGLAGHLA---EALAGQGPAAGLEMLEEKQQVVSH 73
Query: 92 SMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRS 151
S+E IELGL EAQV+LAL++H+ +E+EKQ+LR+Q RRL QEN WLR+EL TQ+RL+ S
Sbjct: 74 SLEAIELGLGEAQVLLALSAHVGALEAEKQRLRSQARRLAQENVWLREELEETQRRLRAS 133
Query: 152 EQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR 211
E++VAQLEEEK+HLEFLGQLRQYD S++ E +DSL LFP+EEEE
Sbjct: 134 EESVAQLEEEKRHLEFLGQLRQYDPPAE-SQQSESPPRRDSLASLFPSEEEERKG---PE 189
Query: 212 GQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVA 271
GA AAQQGGYEIPARLRTLHNLVIQYA QGRYEVAVPLC+QALEDLER+SG HPDVA
Sbjct: 190 AAGAAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVA 249
Query: 272 TMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKE 331
TMLNILALVYRDQNKYKEA LL+DAL IRE TLGP+HPAVAATLNNLAVLYGKRG+Y+E
Sbjct: 250 TMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYRE 309
Query: 332 AEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGP 391
AEPLCQRALEIREKVLG +HPDVAKQLNNLALLCQNQGK+E VER+Y RAL+IYE GP
Sbjct: 310 AEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGP 369
Query: 392 DNPNVARTKNNLASCYLKQGKYAEAETLYKEIL 424
+PNVA+TKNNLAS YLKQ KY +AE LYKEIL
Sbjct: 370 HDPNVAKTKNNLASAYLKQNKYQQAEELYKEIL 402
Score = 75.1 bits (183), Expect = 2e-13
Identities = 96/347 (27%), Positives = 127/347 (36%), Gaps = 104/347 (29%)
Query: 348 GTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCY 407
G P + L+NL + QG+YE ++AL E G +P+VA N LA Y
Sbjct: 200 GYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVY 259
Query: 408 LKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSKSRHHEGGTPYAEY 467
Q KY EA L + L + RE+ H
Sbjct: 260 RDQNKYKEATDLLHDAL----------------------QIREQTLGPEH---------- 287
Query: 468 GGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECALRSRRQ-----GTDPISQT 522
P V TL NL LY ++G+ AE L + AL R + D Q
Sbjct: 288 -----------PAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQL 336
Query: 523 KVAELLGESDGRRTSQE--------------GPGD----------------SVKFEGGED 552
LL ++ G+ E GP D K++ E+
Sbjct: 337 NNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEE 396
Query: 553 ---------------ASVAVEWSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPR 597
+ +GD L+RS SL KIR+ +RR SE LV +L+G E
Sbjct: 397 LYKEILHKEDLPAPLGAPNTGTAGDAEQALRRSSSLSKIRESIRRGSEKLVSRLRG-EAA 455
Query: 598 PSSSNMKRAASLNYLN--QPSAAPLQ--------VSRGLSASTMDLS 634
++ MKRA SLN LN P A Q R LSAST DLS
Sbjct: 456 AGAAGMKRAMSLNTLNVDAPRAPGTQFPSWHLDKAPRTLSASTQDLS 502
>gi|34304360 nephrocystin 3 [Homo sapiens]
Length = 1330
Score = 147 bits (370), Expect = 4e-35
Identities = 116/352 (32%), Positives = 156/352 (44%), Gaps = 48/352 (13%)
Query: 226 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQN 285
P ++LH L Y ++ A L KQALE E G HP A L LA +Y+ QN
Sbjct: 982 PRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAYGADHPYTARELEALATLYQKQN 1041
Query: 286 KYKEAAH------------------------LLNDALSIRESTLGPDHPAVAATLNNLAV 321
KY++A H L AL + E TLG D P A TLN L V
Sbjct: 1042 KYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQLEELTLGKDTPDNARTLNELGV 1101
Query: 322 LYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRA 381
LY + + A+ +R+LE+RE+VLG +HPD A+ LNNLA LC + +Y+ E Y+RA
Sbjct: 1102 LYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYDKAEELYERA 1161
Query: 382 LAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKP 441
L I L PD+P++A T +LA Y K GK +A LY E+ + FG
Sbjct: 1162 LDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLY-ELAVEIRQKSFGPKHPSVAT 1220
Query: 442 IWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKV-------SSPTVNTTLRNLGALYRR 494
++ S+ + H P E +A K+ P V TL+NL L
Sbjct: 1221 ALVNLAVL--YSQMKKHVEALPLYE-----RALKIYEDSLGRMHPRVGETLKNLAVLSYE 1273
Query: 495 QGKLEAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVK 546
G E A L + A+ + T LLG R S G S+K
Sbjct: 1274 GGDFEKAAELYKRAMEIKEAET---------SLLGGKAPSRHSSSGDTFSLK 1316
Score = 146 bits (368), Expect = 7e-35
Identities = 84/203 (41%), Positives = 111/203 (54%)
Query: 222 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 281
G + P RTL+ L + Y Q E A K++LE ER G HPD A LN LA +
Sbjct: 1086 GKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLNNLAALC 1145
Query: 282 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALE 341
++ +Y +A L AL IR L PDHP++A T+ +LA+LY K GK +A PL + A+E
Sbjct: 1146 NEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLYELAVE 1205
Query: 342 IREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKN 401
IR+K G HP VA L NLA+L K+ Y+RAL IYE LG +P V T
Sbjct: 1206 IRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERALKIYEDSLGRMHPRVGETLK 1265
Query: 402 NLASCYLKQGKYAEAETLYKEIL 424
NLA + G + +A LYK +
Sbjct: 1266 NLAVLSYEGGDFEKAAELYKRAM 1288
Score = 122 bits (306), Expect = 1e-27
Identities = 79/227 (34%), Positives = 113/227 (49%), Gaps = 24/227 (10%)
Query: 222 GYEIPARLRTLHNLVIQYAAQGRYEVA------------------------VPLCKQALE 257
G + P R L L Y Q +YE A L ++AL+
Sbjct: 1020 GADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQ 1079
Query: 258 DLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLN 317
E T G+ PD A LN L ++Y QN + A L +L +RE LGPDHP A +LN
Sbjct: 1080 LEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLN 1139
Query: 318 NLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERY 377
NLA L ++ +Y +AE L +RAL+IR + L +HP +A + +LA+L + GK +
Sbjct: 1140 NLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPL 1199
Query: 378 YQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEIL 424
Y+ A+ I + GP +P+VA NLA Y + K+ EA LY+ L
Sbjct: 1200 YELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERAL 1246
Score = 112 bits (281), Expect = 8e-25
Identities = 87/297 (29%), Positives = 131/297 (44%), Gaps = 68/297 (22%)
Query: 246 EVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTL 305
+ VPL +++LE E HP VA L+ LA VY K+ A L AL I E+
Sbjct: 961 QAIVPL-QRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAY 1019
Query: 306 GPDHPAVAATLNNLAVLYGKRGKYKEAEP------------------------LCQRALE 341
G DHP A L LA LY K+ KY++AE L +RAL+
Sbjct: 1020 GADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQ 1079
Query: 342 IREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKN 401
+ E LG + PD A+ LN L +L Q E +++ +R+L + E LGPD+P+ A++ N
Sbjct: 1080 LEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLN 1139
Query: 402 NLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSKSRHHEGG 461
NLA+ ++ +Y +AE LY+ L
Sbjct: 1140 NLAALCNEKKQYDKAEELYERALDIRR--------------------------------- 1166
Query: 462 TPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECALRSRRQGTDP 518
+A P++ T+++L LY++ GKL+ A L E A+ R++ P
Sbjct: 1167 ----------RALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGP 1213
Score = 108 bits (269), Expect = 2e-23
Identities = 63/167 (37%), Positives = 93/167 (55%)
Query: 222 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 281
G + P ++L+NL + +Y+ A L ++AL+ R HP +A + LA++Y
Sbjct: 1128 GPDHPDCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILY 1187
Query: 282 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALE 341
+ K +A L A+ IR+ + GP HP+VA L NLAVLY + K+ EA PL +RAL+
Sbjct: 1188 KKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERALK 1247
Query: 342 IREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQ 388
I E LG HP V + L NLA+L G +E Y+RA+ I E +
Sbjct: 1248 IYEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAAELYKRAMEIKEAE 1294
>gi|87162455 hypothetical protein LOC23277 [Homo sapiens]
Length = 1309
Score = 62.0 bits (149), Expect = 2e-09
Identities = 49/194 (25%), Positives = 80/194 (41%), Gaps = 7/194 (3%)
Query: 242 QGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIR 301
QG + L +AL G H + L +LA ++ Y EA A+ +
Sbjct: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
Query: 302 ESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNL 361
E +G +HP +LA+ + A L RA + V G +HP++A NN+
Sbjct: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
Query: 362 ALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKY-------A 414
L+ +Y+ R+ + ALA+ GP VA + + +A Y + ++
Sbjct: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
Query: 415 EAETLYKEILTRAH 428
E T+YK L H
Sbjct: 1171 EGYTIYKTQLGEDH 1184
Score = 47.4 bits (111), Expect = 4e-05
Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 8/186 (4%)
Query: 224 EIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRD 283
E A LR L L + G Y A+ ++A+ ER G HP+ LAL
Sbjct: 1018 ETCACLRLLARL---HYIMGDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFA 1074
Query: 284 QNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIR 343
++ A LL A + G DHP +A NN+ ++ +Y + + AL +
Sbjct: 1075 SSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVS 1134
Query: 344 EKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNL 403
K G VA + +A + +++ ++ + ++ + IY+ QLG D+ K
Sbjct: 1135 TKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDH-----EKTKE 1189
Query: 404 ASCYLK 409
+S YLK
Sbjct: 1190 SSEYLK 1195
Score = 33.9 bits (76), Expect = 0.47
Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 325 KRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAI 384
++G KE L AL + V G H + L LA L G Y Q+A+ +
Sbjct: 990 QQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLM 1049
Query: 385 YEGQLGPDNPNVARTKNNLA-SCYLKQGKYAEAETLYK 421
E +G ++PN + +LA C+ LY+
Sbjct: 1050 SERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYR 1087
>gi|18104962 amyloid beta precursor protein-binding protein 2 [Homo
sapiens]
Length = 585
Score = 55.5 bits (132), Expect = 2e-07
Identities = 48/190 (25%), Positives = 86/190 (45%), Gaps = 13/190 (6%)
Query: 236 VIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRD-----------Q 284
V QY++ G+++ A+ ++A+ + H +A+ + AL+ + Q
Sbjct: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
Query: 285 NKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIRE 344
+EA L +L + + G + A NL LY K+KEAE + +A++I+E
Sbjct: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
Query: 345 KVLGTNHPDVAKQLNNLALLCQ-NQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNL 403
++LG +VA + +LA L + +YE E+ Y R++AI + G + L
Sbjct: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
Query: 404 ASCYLKQGKY 413
Y G Y
Sbjct: 521 IKLYNSIGNY 530
Score = 38.1 bits (87), Expect = 0.025
Identities = 47/194 (24%), Positives = 75/194 (38%), Gaps = 21/194 (10%)
Query: 245 YEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIREST 304
++ A L K A+ G HP + L + + ++ + AL IR+S
Sbjct: 262 FKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSV 321
Query: 305 LGPDHPAVAATLNNLA----VLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQ--- 357
G + VA +LA V GK+ A +RA+ I +L +H +A
Sbjct: 322 FGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRV 381
Query: 358 ----LNNLALLCQNQGKYEAVERYYQRA-------LAIYEGQLGPDNPNVARTKNNLASC 406
L +A+ C N+ E +R Q A L + + G N A+ NL
Sbjct: 382 KALILEEIAIDCHNK---ETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRL 438
Query: 407 YLKQGKYAEAETLY 420
Y K+ EAE ++
Sbjct: 439 YQSMRKFKEAEEMH 452
Score = 33.9 bits (76), Expect = 0.47
Identities = 24/99 (24%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Query: 234 NLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYR-DQNKYKEAAH 292
NL Y + +++ A + +A++ E+ G+ +VA + LA +Y D N+Y+ A
Sbjct: 434 NLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEK 493
Query: 293 LLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKE 331
L +++I + G + + L LY G Y++
Sbjct: 494 LYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
>gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens]
Length = 501
Score = 54.3 bits (129), Expect = 3e-07
Identities = 43/173 (24%), Positives = 86/173 (49%), Gaps = 15/173 (8%)
Query: 284 QNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLA--VLYGKRGKYKEAEPLCQRALE 341
+ K + L D +S+ E H + L+ A +L+ K+ +A+ + ++AL+
Sbjct: 331 EEKIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS--QAQRMYEKALQ 386
Query: 342 IREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKN 401
I E++ G HP +++LA QG+++ Y QRA + Q+ ++P + +
Sbjct: 387 ISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLAR-QI--NHPELHMVLS 443
Query: 402 NLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSK 454
NLA+ + + +Y +A+ +Y+E L +A +++ D + EE E+SK
Sbjct: 444 NLAAVLMHRERYTQAKEIYQEALKQAKLKK------DEISVQHIREELAELSK 490
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 51.2 bits (121), Expect = 3e-06
Identities = 47/157 (29%), Positives = 65/157 (41%), Gaps = 24/157 (15%)
Query: 268 PDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRG 327
P+ A + LA VY +Q A A+ ++ P NLA ++G
Sbjct: 246 PNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ--------PHFPDAYCNLANALKEKG 297
Query: 328 KYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEG 387
EAE AL + P A LNNLA + + QG E R Y++AL ++
Sbjct: 298 SVAEAEDCYNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF-- 347
Query: 388 QLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEIL 424
P A +NLAS +QGK EA YKE +
Sbjct: 348 ------PEFAAAHSNLASVLQQQGKLQEALMHYKEAI 378
Score = 49.7 bits (117), Expect = 8e-06
Identities = 48/168 (28%), Positives = 69/168 (41%), Gaps = 24/168 (14%)
Query: 257 EDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATL 316
ED T+ R P A LN LA + R+Q +EA L AL + P AA
Sbjct: 303 EDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV--------FPEFAAAH 354
Query: 317 NNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVER 376
+NLA + ++GK +EA + A+ I P A +N+ + + +
Sbjct: 355 SNLASVLQQQGKLQEALMHYKEAIRIS--------PTFADAYSNMGNTLKEMQDVQGALQ 406
Query: 377 YYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEIL 424
Y RA+ I NP A +NLAS + G EA Y+ L
Sbjct: 407 CYTRAIQI--------NPAFADAHSNLASIHKDSGNIPEAIASYRTAL 446
Score = 40.0 bits (92), Expect = 0.007
Identities = 58/255 (22%), Positives = 98/255 (38%), Gaps = 43/255 (16%)
Query: 265 RGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYG 324
R PD +L +L+ ++ + +AH L+I+++ P +A +NL +Y
Sbjct: 39 RQEPDNTGVLLLLSSIHFQCRRLDRSAHF--STLAIKQN------PLLAEAYSNLGNVYK 90
Query: 325 KRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAI 384
+RG+ +EA + AL ++ PD NLA G E + Y AL
Sbjct: 91 ERGQLQEAIEHYRHALRLK--------PDFIDGYINLAAALVAAGDMEGAVQAYVSALQY 142
Query: 385 YEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLY-KEILTRAHV----QEFGSVDDDH 439
NP++ +++L + G+ EA+ Y K I T+ + G V +
Sbjct: 143 --------NPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQ 194
Query: 440 KPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLR------------- 486
IW+ A E + + Y G K ++ V LR
Sbjct: 195 GEIWL-AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHG 253
Query: 487 NLGALYRRQGKLEAA 501
NL +Y QG ++ A
Sbjct: 254 NLACVYYEQGLIDLA 268
Score = 35.8 bits (81), Expect = 0.12
Identities = 50/181 (27%), Positives = 74/181 (40%), Gaps = 32/181 (17%)
Query: 226 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQN 285
P +L+NL QG E AV L ++ALE P+ A + LA V + Q
Sbjct: 314 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF--------PEFAAAHSNLASVLQQQG 365
Query: 286 KYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREK 345
K +EA +A+ I P A +N+ KE + + Q AL+ +
Sbjct: 366 KLQEALMHYKEAIRI--------SPTFADAYSNMG------NTLKEMQDV-QGALQCYTR 410
Query: 346 VLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLAS 405
+ N P A +NLA + ++ G Y+ AL +L PD P+ NLA
Sbjct: 411 AIQIN-PAFADAHSNLASIHKDSGNIPEAIASYRTAL-----KLKPDFPD---AYCNLAH 461
Query: 406 C 406
C
Sbjct: 462 C 462
Score = 30.0 bits (66), Expect = 6.8
Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 18/143 (12%)
Query: 367 NQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTR 426
N G R + RA+A Y L +PN A NLA Y +QG A Y+ +
Sbjct: 220 NLGNVLKEARIFDRAVAAYLRALSL-SPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIEL 278
Query: 427 AHVQEFGSVDDDHKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLR 486
H P + ++ + +G AE Y PT +L
Sbjct: 279 ----------QPHFP-----DAYCNLANALKEKGSVAEAE--DCYNTALRLCPTHADSLN 321
Query: 487 NLGALYRRQGKLEAAETLEECAL 509
NL + R QG +E A L AL
Sbjct: 322 NLANIKREQGNIEEAVRLYRKAL 344
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 51.2 bits (121), Expect = 3e-06
Identities = 47/157 (29%), Positives = 65/157 (41%), Gaps = 24/157 (15%)
Query: 268 PDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRG 327
P+ A + LA VY +Q A A+ ++ P NLA ++G
Sbjct: 256 PNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ--------PHFPDAYCNLANALKEKG 307
Query: 328 KYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEG 387
EAE AL + P A LNNLA + + QG E R Y++AL ++
Sbjct: 308 SVAEAEDCYNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF-- 357
Query: 388 QLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEIL 424
P A +NLAS +QGK EA YKE +
Sbjct: 358 ------PEFAAAHSNLASVLQQQGKLQEALMHYKEAI 388
Score = 49.7 bits (117), Expect = 8e-06
Identities = 48/168 (28%), Positives = 69/168 (41%), Gaps = 24/168 (14%)
Query: 257 EDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATL 316
ED T+ R P A LN LA + R+Q +EA L AL + P AA
Sbjct: 313 EDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV--------FPEFAAAH 364
Query: 317 NNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVER 376
+NLA + ++GK +EA + A+ I P A +N+ + + +
Sbjct: 365 SNLASVLQQQGKLQEALMHYKEAIRIS--------PTFADAYSNMGNTLKEMQDVQGALQ 416
Query: 377 YYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEIL 424
Y RA+ I NP A +NLAS + G EA Y+ L
Sbjct: 417 CYTRAIQI--------NPAFADAHSNLASIHKDSGNIPEAIASYRTAL 456
Score = 40.0 bits (92), Expect = 0.007
Identities = 58/255 (22%), Positives = 98/255 (38%), Gaps = 43/255 (16%)
Query: 265 RGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYG 324
R PD +L +L+ ++ + +AH L+I+++ P +A +NL +Y
Sbjct: 49 RQEPDNTGVLLLLSSIHFQCRRLDRSAHF--STLAIKQN------PLLAEAYSNLGNVYK 100
Query: 325 KRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAI 384
+RG+ +EA + AL ++ PD NLA G E + Y AL
Sbjct: 101 ERGQLQEAIEHYRHALRLK--------PDFIDGYINLAAALVAAGDMEGAVQAYVSALQY 152
Query: 385 YEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLY-KEILTRAHV----QEFGSVDDDH 439
NP++ +++L + G+ EA+ Y K I T+ + G V +
Sbjct: 153 --------NPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQ 204
Query: 440 KPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLR------------- 486
IW+ A E + + Y G K ++ V LR
Sbjct: 205 GEIWL-AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHG 263
Query: 487 NLGALYRRQGKLEAA 501
NL +Y QG ++ A
Sbjct: 264 NLACVYYEQGLIDLA 278
Score = 35.8 bits (81), Expect = 0.12
Identities = 50/181 (27%), Positives = 74/181 (40%), Gaps = 32/181 (17%)
Query: 226 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQN 285
P +L+NL QG E AV L ++ALE P+ A + LA V + Q
Sbjct: 324 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF--------PEFAAAHSNLASVLQQQG 375
Query: 286 KYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREK 345
K +EA +A+ I P A +N+ KE + + Q AL+ +
Sbjct: 376 KLQEALMHYKEAIRI--------SPTFADAYSNMG------NTLKEMQDV-QGALQCYTR 420
Query: 346 VLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLAS 405
+ N P A +NLA + ++ G Y+ AL +L PD P+ NLA
Sbjct: 421 AIQIN-PAFADAHSNLASIHKDSGNIPEAIASYRTAL-----KLKPDFPD---AYCNLAH 471
Query: 406 C 406
C
Sbjct: 472 C 472
Score = 30.0 bits (66), Expect = 6.8
Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 18/143 (12%)
Query: 367 NQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTR 426
N G R + RA+A Y L +PN A NLA Y +QG A Y+ +
Sbjct: 230 NLGNVLKEARIFDRAVAAYLRALSL-SPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIEL 288
Query: 427 AHVQEFGSVDDDHKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLR 486
H P + ++ + +G AE Y PT +L
Sbjct: 289 ----------QPHFP-----DAYCNLANALKEKGSVAEAE--DCYNTALRLCPTHADSLN 331
Query: 487 NLGALYRRQGKLEAAETLEECAL 509
NL + R QG +E A L AL
Sbjct: 332 NLANIKREQGNIEEAVRLYRKAL 354
>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
[Homo sapiens]
Length = 836
Score = 50.4 bits (119), Expect = 5e-06
Identities = 42/159 (26%), Positives = 67/159 (42%), Gaps = 16/159 (10%)
Query: 269 DVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGK 328
++A ML L L+ ++ +++ EA H A+ R P +A+ N ++ +G+
Sbjct: 525 NMADMLYNLGLLLQENSRFAEALHYYKLAIGSR--------PTLASAYLNTGIILMNQGR 576
Query: 329 YKEAEPLCQRALEIREKVLGTNHP---DVAKQLNNLALLCQNQGKYEAVERYYQRALAIY 385
+EA + EI ++ L H V L NL L QG YE Y+ A+
Sbjct: 577 TEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQKM 636
Query: 386 EGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEIL 424
Q P + N + Y++ K EAE Y E L
Sbjct: 637 PRQFAPQS-----LYNMMGEAYMRLSKLPEAEHWYMESL 670
Score = 44.7 bits (104), Expect = 3e-04
Identities = 39/153 (25%), Positives = 66/153 (43%), Gaps = 19/153 (12%)
Query: 277 LALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLC 336
L V + Q+K EA +AL R + +A L NL +L + ++ EA
Sbjct: 499 LGNVLKSQSKISEAESAYRNALYYRSN--------MADMLYNLGLLLQENSRFAEALHYY 550
Query: 337 QRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNV 396
+ A+ R P +A N ++ NQG+ E R + + I + L + +
Sbjct: 551 KLAIGSR--------PTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENLKDPHAHK 602
Query: 397 ARTKN---NLASCYLKQGKYAEAETLYKEILTR 426
+ + NL Y +QG Y EA ++YKE + +
Sbjct: 603 SSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQK 635
Score = 40.8 bits (94), Expect = 0.004
Identities = 53/219 (24%), Positives = 84/219 (38%), Gaps = 47/219 (21%)
Query: 232 LHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAA 291
L+NL Y QG YE A+ + K+A++ + R ++ N++ Y +K EA
Sbjct: 609 LYNLGKLYHEQGHYEEALSVYKEAIQKMPRQFA-----PQSLYNMMGEAYMRLSKLPEAE 663
Query: 292 HLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALE---------- 341
H + S+R T DH T L L G++ EAE L +A+E
Sbjct: 664 HWYME--SLRSKT---DHIPAHLTYGKLLALTGRK---SEAEKLFLKAIELDPTKGNCYM 715
Query: 342 -----IREKVLGTNHPDVAKQ-----------LNNLALLCQNQGKYEAVERYYQRALAIY 385
+ E+ ++AK+ + N A + + EA E+YY A +
Sbjct: 716 HYGQFLLEEARLIEAAEMAKKAAELDSTEFDVVFNAAHMLRQASLNEAAEKYYDLAARL- 774
Query: 386 EGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEIL 424
PN NL + G+ +AE Y L
Sbjct: 775 -------RPNYPAALMNLGAILHLNGRLQKAEANYLRAL 806
Score = 30.0 bits (66), Expect = 6.8
Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 18/115 (15%)
Query: 395 NVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSK 454
N A+ NL + Q K +EAE+ Y+ L ++ D + + +E ++
Sbjct: 491 NPAKAWGNLGNVLKSQSKISEAESAYRNALYYR-----SNMADMLYNLGLLLQENSRFAE 545
Query: 455 SRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKL-EAAETLEECA 508
+ H+ YK S PT+ + N G + QG+ EA T +C+
Sbjct: 546 ALHY------------YKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCS 588
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 47.8 bits (112), Expect = 3e-05
Identities = 65/254 (25%), Positives = 104/254 (40%), Gaps = 44/254 (17%)
Query: 257 EDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATL 316
E L R+ + P A + A +DQ + KEA + AL + +P A+ L
Sbjct: 361 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKL--------YPRHASAL 412
Query: 317 NNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVER 376
NNL L EA+ QRAL++ HP + L NL L ++Q K E
Sbjct: 413 NNLGTLTRDTA---EAKMYYQRALQL--------HPQHNRALFNLGNLLKSQEKKE---- 457
Query: 377 YYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVD 436
A+ + + + P A ++LAS +Q ++ EAE +Y+ ++
Sbjct: 458 ---EAITLLKDSI-KYGPEFADAYSSLASLLAEQERFKEAEEIYQ-----TGIKNCPDSS 508
Query: 437 DDHKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQG 496
D H + + G P + +A K+S P+ + + NLG LYR G
Sbjct: 509 DLHNNYGVFLVDT-----------GLPEKAVAHYQQAIKLS-PSHHVAMVNLGRLYRSLG 556
Query: 497 KLEAAETLEECALR 510
+ AE + AL+
Sbjct: 557 ENSMAEEWYKRALQ 570
Score = 41.6 bits (96), Expect = 0.002
Identities = 54/226 (23%), Positives = 86/226 (38%), Gaps = 51/226 (22%)
Query: 226 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQN 285
P R L NL +Q + E A+ L K ++ + P+ A + LA + +Q
Sbjct: 437 PQHNRALFNLGNLLKSQEKKEEAITLLKDSI--------KYGPEFADAYSSLASLLAEQE 488
Query: 286 KYKEAAHL-------------LNDALSIRESTLGPDHPAVA-------------ATLNNL 319
++KEA + L++ + G AVA + NL
Sbjct: 489 RFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNL 548
Query: 320 AVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQ 379
LY G+ AE +RAL++ K A+ L+ L L N G+YE + YQ
Sbjct: 549 GRLYRSLGENSMAEEWYKRALQVAHK---------AEILSPLGALYYNTGRYEEALQIYQ 599
Query: 380 RALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILT 425
A A+ P+ + LA G+ EAE + I++
Sbjct: 600 EAAAL--------QPSQRELRLALAQVLAVMGQTKEAEKMTNHIVS 637
Score = 38.9 bits (89), Expect = 0.015
Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 20/129 (15%)
Query: 276 ILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPL 335
+L+ +Y Q + +A ++ AL ++ P P V ++ L+ +G + L
Sbjct: 648 LLSAIYSKQENHDKALDAIDKALQLK-----PKDPKV------ISELFFTKGNQLREQNL 696
Query: 336 CQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPN 395
+A E + N PD A+ N+ + +GKY + YY+RAL QL PD+
Sbjct: 697 LDKAFESYRVAVQLN-PDQAQAWMNMGGIQHIKGKYVSARAYYERAL-----QLVPDSKL 750
Query: 396 VARTKNNLA 404
+ K NLA
Sbjct: 751 L---KENLA 756
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 47.4 bits (111), Expect = 4e-05
Identities = 117/537 (21%), Positives = 204/537 (37%), Gaps = 77/537 (14%)
Query: 54 LRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLA-LASH 112
L+ + +A L+ L + + LQ+ +G ++A QL R ++ + S + LA L
Sbjct: 437 LKEDARASLERLVKEMAPLQEELSGKG---QEADQLWRRLQELLAHTSSWEEELAELRRE 493
Query: 113 LSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHL-EFLGQL 171
+ EK+ L +VR L ++ Q+L +LA Q + E+ QL ++K HL + +G L
Sbjct: 494 KKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGML 553
Query: 172 RQY-----DEDGHTSEEKEG-DATKDSLDDLFPNEEEEDPSNGLSRGQ-GATAAQQGGYE 224
+ E E+ E SL + + EEE GL Q T Q+G E
Sbjct: 554 ERLAGPPGPELPVAGEKNEALVPVNSSLQEAWGKPEEE--QRGLQEAQLDDTKVQEGSQE 611
Query: 225 IPARL------RTLHNLV-IQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNIL 277
R + L N+V +G+ + A+ QAL+ E + + L
Sbjct: 612 EELRQANRELEKELQNVVGRNQLLEGKLQ-ALQADYQALQQRE----------SAIQGSL 660
Query: 278 ALVYRDQNKYKEAAHLLN-DALSIRESTLGPDHPAVAATLNNLAVLYGKRG---KYKEAE 333
A + +Q + + L++R++ A A+L K G + +E
Sbjct: 661 ASLEAEQASIRHLGDQMEASLLAVRKA----KEAMKAQMAEKEAILQSKEGECQQLREEV 716
Query: 334 PLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKY--------EAVERYYQRALA-- 383
CQ+ E R + L +Q + +L +G+ EA E Q AL+
Sbjct: 717 EQCQQLAEARHRELRALESQCQQQTQLIEVLTAEKGQQGVGPPTDNEARELAAQLALSQA 776
Query: 384 ---IYEGQL----------------GPDNPNVARTKNNLASCYLKQGK-YAEAETLYKEI 423
+++G++ D+ + +++ ++A L++ K + E
Sbjct: 777 QLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEA 836
Query: 424 LTRAHVQEFGSVDDDHKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNT 483
L RAHVQE + + EER + ++ R E E K SS
Sbjct: 837 LNRAHVQELLQCSEREGAL---QEERADEAQQREEELRALQEE----LSQAKCSSEEAQL 889
Query: 484 TLRNLGALYRRQGKLEAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEG 540
L R A ++ CAL ++ + V EL + +EG
Sbjct: 890 EHAELQEQLHRANTDTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREG 946
>gi|17864094 feminization 1 homolog a [Homo sapiens]
Length = 617
Score = 47.0 bits (110), Expect = 5e-05
Identities = 50/178 (28%), Positives = 73/178 (41%), Gaps = 25/178 (14%)
Query: 254 QALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVA 313
QAL ER G HPD + + VY D +K +L AL +++S L P P A
Sbjct: 321 QALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTA 380
Query: 314 ATLNNLAVLY---------GKRGKYKEAEP----LCQRALEIREKVLGTNHPDVAKQLNN 360
++L + A L+ G G + LC+ LEI + T P QLN
Sbjct: 381 SSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQLNK 440
Query: 361 -----LALLCQNQGKYEAVERYYQRALAIYEG-QLGPDNPNVARTKNNLASCYLKQGK 412
L L+C + +E+ + + IY +L P R KNN + +L K
Sbjct: 441 ALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHP------RGKNNFSPLHLAVDK 492
Score = 37.0 bits (84), Expect = 0.056
Identities = 19/81 (23%), Positives = 40/81 (49%)
Query: 327 GKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYE 386
G + + + +AL IRE++LG +HPD + + + + G ++ ++ AL + +
Sbjct: 310 GLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQ 369
Query: 387 GQLGPDNPNVARTKNNLASCY 407
L P +P A + + A +
Sbjct: 370 SNLDPLSPMTASSLLSFAELF 390
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 46.6 bits (109), Expect = 7e-05
Identities = 49/186 (26%), Positives = 86/186 (46%), Gaps = 30/186 (16%)
Query: 10 RPGKVPQARMSGLVLGQRDEPAGHRLSQEEILGSTRLVS-------------QGLEA--- 53
R + Q+ + L Q G RLS+EE+L +T ++ + LEA
Sbjct: 1688 RRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVA 1747
Query: 54 -LRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQ-------LRRSMENIELGLSEAQV 105
++ E + V+Q E ++ E + E+ ++ L R+ EN+E +++ Q
Sbjct: 1748 RMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQK 1807
Query: 106 MLALASHLSTVESEK--QKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQL----E 159
LA A ++ + S K QKL ++VR L E + A Q+ +R E+ + +L E
Sbjct: 1808 RLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAE 1867
Query: 160 EEKKHL 165
E+KK+L
Sbjct: 1868 EDKKNL 1873
Score = 30.8 bits (68), Expect = 4.0
Identities = 38/156 (24%), Positives = 68/156 (43%), Gaps = 15/156 (9%)
Query: 52 EALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLALAS 111
E L+++ ++ Q + I LQ V E+ L +S +E + E L+
Sbjct: 883 EELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKE------LSE 936
Query: 112 HLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHL----EF 167
+ E +L A+ R+L E L+ E+ + L +SE+ E + K+L EF
Sbjct: 937 RVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEF 996
Query: 168 LGQ-LRQYDEDGHTSEEKEGDATKDSLDDLFPNEEE 202
L + + + + +E A + +LDDL EE+
Sbjct: 997 LNEDISKLNRAAKVVQE----AHQQTLDDLHMEEEK 1028
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 45.4 bits (106), Expect = 2e-04
Identities = 52/216 (24%), Positives = 85/216 (39%), Gaps = 11/216 (5%)
Query: 227 ARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNK 286
A+ R L NL + + A+ +Q L + R A+ L YR K
Sbjct: 712 AKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKDRRLE--ASAYAALGTAYRMIQK 769
Query: 287 YKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKV 346
Y +A L + + D P +LA +Y GKY A + L++ +K+
Sbjct: 770 YDKALGYHTQELEVYQEL--SDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKL 827
Query: 347 LGTNHPDVAKQL-NNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNP-NVARTKNNLA 404
P + Q+ N+ + N E Y+++ LA+ + G ++ + R NL
Sbjct: 828 ---KDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLG 884
Query: 405 SCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHK 440
CY G Y EA Y++ L+ A Q + D K
Sbjct: 885 DCYEALGDYEEAIKYYEQYLSVA--QSLNRMQDQAK 918
Score = 42.4 bits (98), Expect = 0.001
Identities = 41/171 (23%), Positives = 72/171 (42%), Gaps = 11/171 (6%)
Query: 257 EDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATL 316
EDL+ + G + L ++++ + Y A L L I + D+ A
Sbjct: 465 EDLKDRAAEGRAS-----SNLGIIHQMKGDYDTALKLHKTHLCIAQEL--SDYAAQGRAY 517
Query: 317 NNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVER 376
N+ Y G Y +A ++ L+I +V + A NLA+ Q G ++ +
Sbjct: 518 GNMGNAYNALGMYDQAVKYHRQELQISMEV--NDRASQASTHGNLAVAYQALGAHDRALQ 575
Query: 377 YYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRA 427
+YQ L I D + AR +NL + + +G+Y +A Y++ L A
Sbjct: 576 HYQNHLNIARELR--DIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLA 624
Score = 35.4 bits (80), Expect = 0.16
Identities = 58/241 (24%), Positives = 93/241 (38%), Gaps = 48/241 (19%)
Query: 224 EIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALE---DLERTSGRGHPDVATMLNILALV 280
+I + R L NL + ++G Y A P +Q L DL+ G G + + L
Sbjct: 589 DIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGK-----VCHNLGYA 643
Query: 281 YRDQNKYKEA----------AHLLNDALSIRES--TLGPDHPAV---------------- 312
+ Y+EA A L+D LS ++ LG A+
Sbjct: 644 HYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSL 703
Query: 313 AATLNNLAVLYGKRGKYKEAEPLCQR----ALEIREKVLGTNHPDVAKQLNNLALLCQNQ 368
A +LNN + G + +C++ A++ E+ LG H ++L A
Sbjct: 704 AQSLNNSQAKFRALGNLGDIF-ICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGT 762
Query: 369 G-----KYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEI 423
KY+ Y+ + L +Y+ D P R +LA+ Y+ GKY A Y+E
Sbjct: 763 AYRMIQKYDKALGYHTQELEVYQEL--SDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQ 820
Query: 424 L 424
L
Sbjct: 821 L 821
Score = 32.3 bits (72), Expect = 1.4
Identities = 62/313 (19%), Positives = 120/313 (38%), Gaps = 20/313 (6%)
Query: 224 EIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDV-ATMLNILALVYR 282
++P R +L Y A G+Y +A ++ L+ ++ P + A + + +
Sbjct: 789 DLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLK---DPSLEAQVYGNMGITKM 845
Query: 283 DQNKYKEAAHLLNDALSIRESTLGPDHPA-VAATLNNLAVLYGKRGKYKEAEPLCQRALE 341
+ N +EA L++ + G + NL Y G Y+EA ++ L
Sbjct: 846 NMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLS 905
Query: 342 IREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKN 401
+ + + D AK L + G + +++ L + +LG + N A+
Sbjct: 906 VAQSL--NRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAH-ELG-EAFNKAQAYG 961
Query: 402 NLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHK--PIWMHAEEREEMSKSRHHE 459
L S + + G Y +A + + L A + +++ D ++ + E + ++H+
Sbjct: 962 ELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQ 1021
Query: 460 GGTPYAEYGGWYKACKVSSPTV-NTTLRNLGALYRRQGKLEAAETLEECALRSRRQGTDP 518
AE + ++PT NLG Y G E A +E L Q D
Sbjct: 1022 LDLQIAE--------ETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDL 1073
Query: 519 ISQTKVAELLGES 531
++T LG +
Sbjct: 1074 AAKTVSYSSLGRT 1086
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 45.1 bits (105), Expect = 2e-04
Identities = 83/375 (22%), Positives = 149/375 (39%), Gaps = 65/375 (17%)
Query: 56 SEHQAVLQSLSQTIECLQQGGHEEGLVHEKAR-QLRRSMENIELGLSEAQVMLALASHLS 114
S A L+ L++ E + +EEGL HE QL+ ++N+E L+E + M
Sbjct: 76 SRKAAALEFLNRFEEAKRT--YEEGLKHEANNPQLKEGLQNMEARLAERKFMNPF----- 128
Query: 115 TVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQY 174
+ + QKL + R + EL ++L+ + ++ + + L L
Sbjct: 129 NMPNLYQKLESDPRTRTLLSDPTYRELI---EQLRNKPSDLGTKLQDPRIMTTLSVLLGV 185
Query: 175 DEDGHTSEEKE-------GDATKDSLDDLFPNEEEEDPSNGLSRGQ-GATAAQQGGYEI- 225
D G EE+E K++ + + E+ L + G A ++ ++
Sbjct: 186 DL-GSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDTA 244
Query: 226 -----------PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATML 274
P + + N Y +G Y LC++A+E + R + + +A
Sbjct: 245 LKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIE-VGRENREDYRQIAKAY 303
Query: 275 NILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEP 334
+ Y + KYK+A H N +L+ + PD VL K ++AE
Sbjct: 304 ARIGNSYFKEEKYKDAIHFYNKSLAEHRT---PD------------VL----KKCQQAE- 343
Query: 335 LCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNP 394
+ L+ +E++ N PD+A + N C +G Y ++Y A+ NP
Sbjct: 344 ---KILKEQERLAYIN-PDLALEEKNKGNECFQKGDYPQAMKHYTEAI--------KRNP 391
Query: 395 NVARTKNNLASCYLK 409
A+ +N A+CY K
Sbjct: 392 KDAKLYSNRAACYTK 406
Score = 38.5 bits (88), Expect = 0.019
Identities = 30/136 (22%), Positives = 59/136 (43%), Gaps = 21/136 (15%)
Query: 310 PAVAATLNNLAVLYGKRGKYKEAEPLCQRALEI-REKVLGTNHPDVAKQLNNLALLCQNQ 368
P + N A +Y ++G Y + LC++A+E+ RE ++ +AK + +
Sbjct: 256 PTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGREN--REDYRQIAKAYARIGNSYFKE 313
Query: 369 GKYEAVERYYQRALAIY------------------EGQLGPDNPNVARTKNNLASCYLKQ 410
KY+ +Y ++LA + + +L NP++A + N + ++
Sbjct: 314 EKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQK 373
Query: 411 GKYAEAETLYKEILTR 426
G Y +A Y E + R
Sbjct: 374 GDYPQAMKHYTEAIKR 389
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 43.9 bits (102), Expect = 5e-04
Identities = 37/163 (22%), Positives = 77/163 (47%), Gaps = 9/163 (5%)
Query: 52 EALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLALAS 111
E +R + + +L+ QT E +Q G +E + E+ Q+R E + + + M
Sbjct: 269 EQMREQEEQMLKQKEQT-EQEEQTGEQEEQMREQEEQMREQEEQMR---EQEEQMREQEE 324
Query: 112 HLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQ-RLQRSEQAVAQLEEEKKHLEFLGQ 170
+ E + + + Q+ +E W ++E G Q+ ++Q+ E+ V + EE+ + E Q
Sbjct: 325 QMGKQEEQMWEQKEQMWEQ-KEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE--EQ 381
Query: 171 LRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQ 213
+R+ +E EE+ G+ K+ + + E++ G + Q
Sbjct: 382 MRKQEEQMRKQEEQMGE-QKEQMGEQKEQMREQEEQMGEQKEQ 423
Score = 39.3 bits (90), Expect = 0.011
Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 52 EALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENI-----ELGLSEAQVM 106
E +R + + + + Q E +Q G +E + E+ Q+ E + ++G E Q M
Sbjct: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ-M 361
Query: 107 LALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLE 166
+ E + +K Q+R+ QE Q + E +Q+ Q EQ E+E++ E
Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRK--QEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGE 419
Query: 167 FLGQLRQYDEDGHTSEEKE 185
Q+R+ +E H E+KE
Sbjct: 420 QKEQMRKQEE--HMGEQKE 436
Score = 38.1 bits (87), Expect = 0.025
Identities = 32/162 (19%), Positives = 68/162 (41%), Gaps = 26/162 (16%)
Query: 25 GQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHE 84
GQ E G QEE +G E ++ + + + + Q + +Q G +E V +
Sbjct: 192 GQMGEQEGQMGEQEEQMGEQE------EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
Query: 85 KARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGT 144
+ Q+++ E + +++++R Q ++ ++ + + + T
Sbjct: 246 QEEQVQKQEEQMR--------------------KQEEQMREQEEQMREQEEQMLKQKEQT 285
Query: 145 QQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEG 186
+Q Q EQ E+E++ E Q+R+ +E EE+ G
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMG 327
Score = 36.6 bits (83), Expect = 0.073
Identities = 40/180 (22%), Positives = 78/180 (43%), Gaps = 6/180 (3%)
Query: 25 GQRDEPAGHRLSQE-EILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVH 83
GQ E G QE ++ V + +R + V + Q E Q +EG V
Sbjct: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 181
Query: 84 EKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAG 143
E+ Q+R + ++G E Q M + E + QK Q+ ++ + +++
Sbjct: 182 EQEGQVRE--QEGQMGEQEGQ-MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238
Query: 144 TQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEE 203
++++Q+ E+ V + EE+ + E Q+R+ +E EE+ + + + E+EE
Sbjct: 239 QEEQVQKQEEQVQKQEEQMRKQE--EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEE 296
>gi|238908495 similar to pleckstrin homology domain protein (5V327)
[Homo sapiens]
Length = 506
Score = 43.5 bits (101), Expect = 6e-04
Identities = 30/144 (20%), Positives = 71/144 (49%), Gaps = 7/144 (4%)
Query: 51 LEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLAL- 109
++ LR E + + + L T CL+ E+ + L++++E + + + ML
Sbjct: 205 VQELRMEQEQIKRELELTARCLKGVEQEKKELRHLTESLQQTLEELSIEKKKTLEMLEEN 264
Query: 110 ASHLSTVESEKQK------LRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKK 163
+HL T+ ++ ++ L + +R++ ++ Q L +E ++R++ +E+ LEEE++
Sbjct: 265 ENHLQTLANQSEQPPPSGGLHSNLRQIEEKMQQLLEEKLLAEKRMKENEERSRALEEERE 324
Query: 164 HLEFLGQLRQYDEDGHTSEEKEGD 187
Q Q T+E+++ +
Sbjct: 325 FYSSQSQALQNSLQELTAEKQQAE 348
Score = 39.7 bits (91), Expect = 0.009
Identities = 52/220 (23%), Positives = 95/220 (43%), Gaps = 27/220 (12%)
Query: 6 FGVTRPGKVPQARMSGLVLGQRDEPA---GHRLSQEEILGSTRLVS-------QGLEALR 55
F + G +P + G ++ ++EP+ ++S ++ G+ L + Q LE L+
Sbjct: 76 FNIHPKGVIP---LGGCLVEPKEEPSMPYAMKISHQDFHGNILLAAESEFEQTQWLEMLQ 132
Query: 56 SEHQAVLQSLSQTIECLQQGGHEEGL--VHEKARQLRRSMENIELGLSEAQVMLALASHL 113
+ ++ +Q E + + +GL EK L + ME E + + L
Sbjct: 133 ESGKVTWKN-AQLGEAMIKSLEAQGLQLAKEKQEYLDKLMEETEELCLQREQREELERLN 191
Query: 114 STVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQ 173
+E+EKQ+ V+ L E + ++ EL T + L+ EQ EKK L L + Q
Sbjct: 192 QVLEAEKQQFEEVVQELRMEQEQIKRELELTARCLKGVEQ-------EKKELRHLTESLQ 244
Query: 174 YDEDGHTSEEKEG----DATKDSLDDLFPNEEEEDPSNGL 209
+ + E+K+ + ++ L L E+ PS GL
Sbjct: 245 QTLEELSIEKKKTLEMLEENENHLQTLANQSEQPPPSGGL 284
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 43.1 bits (100), Expect = 8e-04
Identities = 41/162 (25%), Positives = 71/162 (43%), Gaps = 24/162 (14%)
Query: 46 LVSQGLEALRSEHQAVLQS------------LSQTIECLQQGGHEEGLVHEKARQLRRSM 93
+++Q LE L+ +H+ LQS L+ T+ QG H+ EK L
Sbjct: 1011 ILTQELEKLKRKHEGELQSVRDHLRTEVSTELAGTVAHELQGVHQGEFGSEKKTALHEKE 1070
Query: 94 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQ--RS 151
E + L ++AQ + EK+ L Q+++ + Q L+D++ ++ RS
Sbjct: 1071 ETLRLQSAQAQPFH---------QEEKESLSLQLQKKNHQVQQLKDQVLSLSHEIEECRS 1121
Query: 152 EQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSL 193
E V Q E+++ E L D + S + G A +D+L
Sbjct: 1122 ELEVLQQRRERENREGANLLSMLKADVNLSHSERG-ALQDAL 1162
Score = 40.0 bits (92), Expect = 0.007
Identities = 49/192 (25%), Positives = 79/192 (41%), Gaps = 34/192 (17%)
Query: 16 QARMSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQG 75
Q+ M L + E A R E+I + L L S HQA ++ L + ++
Sbjct: 370 QSEMEDLQNQFQKELAEQRAELEKIFQDKNQAERALRNLESHHQAAIEKLREDLQS---- 425
Query: 76 GHEEGLVHEKARQLRRSMENIELGL--SEAQVMLALASHLSTVESEKQKLRAQVRRLCQE 133
E G R +E++E SE + L L + ++ E K + + ++RRL
Sbjct: 426 --EHG----------RCLEDLEFKFKESEKEKQLELENLQASYEDLKAQSQEEIRRL--- 470
Query: 134 NQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTS---------EEK 184
W + + A T + Q + QL +E L QL+Q ++ H S E+K
Sbjct: 471 --WSQLDSARTSR--QELSELHEQLLARTSRVEDLEQLKQREKTQHESELEQLRIYFEKK 526
Query: 185 EGDATKDSLDDL 196
DA K +DL
Sbjct: 527 LRDAEKTYQEDL 538
Score = 31.2 bits (69), Expect = 3.0
Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 17/163 (10%)
Query: 44 TRLVSQGLEALRSEHQAV--LQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLS 101
++L + L L+ E Q+ L+ L ++E Q+ V K Q + EL +
Sbjct: 2667 SQLEEEQLRHLQRESQSAKALEELRASLET-QRAQSSRLCVALKHEQTAKDNLQKELRIE 2725
Query: 102 EAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQA------- 154
++ LA S + ++ L A+ R + ++ LR E T+Q QR+++A
Sbjct: 2726 HSRCEALLAQERSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQ 2785
Query: 155 -----VAQLEEEKKH-LEFLGQLRQYDEDG-HTSEEKEGDATK 190
+ +L+EEK ++ L + + H+ ++ E +A K
Sbjct: 2786 AHHALLQKLKEEKSRVVDLQAMLEKVQQQALHSQQQLEAEAQK 2828
>gi|145699105 connexin40.1 [Homo sapiens]
Length = 370
Score = 43.1 bits (100), Expect = 8e-04
Identities = 49/169 (28%), Positives = 79/169 (46%), Gaps = 18/169 (10%)
Query: 474 CKVSSPTVNTTLRN-LGALYRRQGKLEAAETLEECALRSRRQGTDPISQT--KVAELLGE 530
C VS PT + L L A+ L A+ + R RR+ P S + K + G
Sbjct: 186 CYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRRPGPPTSPSIRKQSGASGH 245
Query: 531 SDGRRTSQEGPGDSVKFEGGEDASVAVEWSGDGSGTLQRSGSLG---KIRD-----VLRR 582
++GRRT +EG + E G A G+G+G+ +R+ + KI D V
Sbjct: 246 AEGRRTDEEGGRE----EEGAPAPPGARAGGEGAGSPRRTSRVSGHTKIPDEDESEVTSS 301
Query: 583 SSELLVRKLQGTEPRPSSSNMKRAASLNYLNQPSAAPLQVSRGLSASTM 631
+SE L R+ +G R ++ + + + S QPSAAP +++ S S++
Sbjct: 302 ASEKLGRQPRGRPHREAAQDPRGSGS---EEQPSAAPSRLAAPPSCSSL 347
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 42.0 bits (97), Expect = 0.002
Identities = 53/252 (21%), Positives = 114/252 (45%), Gaps = 8/252 (3%)
Query: 39 EILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIEL 98
+++ + R ++ +E S + L S + L++ EE A R S E ++
Sbjct: 738 QVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQS 797
Query: 99 GLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQ- 157
L E++V + LAS L EK+K+ ++V ++ E ++ E Q L+ EQ V +
Sbjct: 798 SL-ESEVSV-LASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNEL 855
Query: 158 LEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATA 217
L++ ++ E L ++++Y E EE + + ++ +E + + LS ++
Sbjct: 856 LQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSK 915
Query: 218 AQQGGYE-IPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNI 276
Q E + +++ L N + + Q + ++V + L G+ DV +L
Sbjct: 916 RQSQQLEALQQQVKQLQNQLAECKKQHQEVISV----YRMHLLYAVQGQMDEDVQKVLKQ 971
Query: 277 LALVYRDQNKYK 288
+ + ++Q++ K
Sbjct: 972 ILTMCKNQSQKK 983
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,250,381
Number of Sequences: 37866
Number of extensions: 1127160
Number of successful extensions: 6163
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 475
Number of HSP's that attempted gapping in prelim test: 4709
Number of HSP's gapped (non-prelim): 1547
length of query: 637
length of database: 18,247,518
effective HSP length: 109
effective length of query: 528
effective length of database: 14,120,124
effective search space: 7455425472
effective search space used: 7455425472
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.