BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|41680688 ceramide kinase-like isoform a [Homo sapiens] (532 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|41680688 ceramide kinase-like isoform a [Homo sapiens] 1071 0.0 gi|71896723 ceramide kinase-like isoform b [Homo sapiens] 1057 0.0 gi|237757361 ceramide kinase-like isoform g [Homo sapiens] 949 0.0 gi|71896711 ceramide kinase-like isoform d [Homo sapiens] 867 0.0 gi|71896725 ceramide kinase-like isoform c [Homo sapiens] 533 e-151 gi|20336726 ceramide kinase [Homo sapiens] 209 5e-54 gi|8922701 acylglycerol kinase [Homo sapiens] 70 6e-12 gi|217272885 sphingosine kinase 1 isoform 3 [Homo sapiens] 68 2e-11 gi|217272883 sphingosine kinase 1 isoform 3 [Homo sapiens] 68 2e-11 gi|21361088 sphingosine kinase 1 isoform 1 [Homo sapiens] 68 2e-11 gi|217272880 sphingosine kinase 1 isoform 2 [Homo sapiens] 68 2e-11 gi|21361699 sphingosine kinase 2 [Homo sapiens] 67 5e-11 gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 33 0.50 gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 33 0.50 gi|39930469 brix domain containing 1 [Homo sapiens] 32 1.9 gi|4502897 cleft lip and palate associated transmembrane protein... 32 1.9 gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo s... 30 4.2 gi|33356148 formin-like 1 [Homo sapiens] 30 4.2 gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 30 5.5 gi|55743118 RAB3 GTPase-activating protein [Homo sapiens] 30 7.2 gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo ... 30 7.2 gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens] 29 9.4 gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens] 29 9.4 gi|11055976 carbohydrate (N-acetylglucosamine 6-O) sulfotransfer... 29 9.4 >gi|41680688 ceramide kinase-like isoform a [Homo sapiens] Length = 532 Score = 1071 bits (2771), Expect = 0.0 Identities = 532/532 (100%), Positives = 532/532 (100%) Query: 1 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD Sbjct: 1 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60 Query: 61 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI Sbjct: 61 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120 Query: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK Sbjct: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180 Query: 181 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDGVVCVGGDGSASEVA 240 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDGVVCVGGDGSASEVA Sbjct: 181 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDGVVCVGGDGSASEVA 240 Query: 241 HALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTNVLAHSLHGVPHVITATLHIIMGH 300 HALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTNVLAHSLHGVPHVITATLHIIMGH Sbjct: 241 HALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTNVLAHSLHGVPHVITATLHIIMGH 300 Query: 301 VQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAE 360 VQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAE Sbjct: 301 VQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAE 360 Query: 361 DCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQMIQGQFLNVSIMAIPCLCSVAPRGLAP 420 DCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQMIQGQFLNVSIMAIPCLCSVAPRGLAP Sbjct: 361 DCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQMIQGQFLNVSIMAIPCLCSVAPRGLAP 420 Query: 421 NTRLNNGSMALIIARNTSRPEFIKHLKRYASVKNQFNFPFVETYTVEEVKVHPRNNTGGY 480 NTRLNNGSMALIIARNTSRPEFIKHLKRYASVKNQFNFPFVETYTVEEVKVHPRNNTGGY Sbjct: 421 NTRLNNGSMALIIARNTSRPEFIKHLKRYASVKNQFNFPFVETYTVEEVKVHPRNNTGGY 480 Query: 481 NPEEEEDETASENCFPWNVDGDLMEVASEVHIRLHPRLISLYGGSMEEMIPK 532 NPEEEEDETASENCFPWNVDGDLMEVASEVHIRLHPRLISLYGGSMEEMIPK Sbjct: 481 NPEEEEDETASENCFPWNVDGDLMEVASEVHIRLHPRLISLYGGSMEEMIPK 532 >gi|71896723 ceramide kinase-like isoform b [Homo sapiens] Length = 558 Score = 1057 bits (2734), Expect = 0.0 Identities = 532/558 (95%), Positives = 532/558 (95%), Gaps = 26/558 (4%) Query: 1 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD Sbjct: 1 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60 Query: 61 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI Sbjct: 61 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120 Query: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK Sbjct: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180 Query: 181 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDG-------------- 226 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDG Sbjct: 181 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQ 240 Query: 227 ------------VVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 274 VVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG Sbjct: 241 RLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 300 Query: 275 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA 334 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA Sbjct: 301 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA 360 Query: 335 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM 394 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM Sbjct: 361 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM 420 Query: 395 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN 454 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN Sbjct: 421 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN 480 Query: 455 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL 514 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL Sbjct: 481 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL 540 Query: 515 HPRLISLYGGSMEEMIPK 532 HPRLISLYGGSMEEMIPK Sbjct: 541 HPRLISLYGGSMEEMIPK 558 >gi|237757361 ceramide kinase-like isoform g [Homo sapiens] Length = 514 Score = 949 bits (2452), Expect = 0.0 Identities = 487/558 (87%), Positives = 488/558 (87%), Gaps = 70/558 (12%) Query: 1 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD Sbjct: 1 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60 Query: 61 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI Sbjct: 61 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120 Query: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILA Sbjct: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILA-------------------- 160 Query: 181 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDG-------------- 226 +MEYEGHALSLLKECELQGFDG Sbjct: 161 ------------------------VMEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQ 196 Query: 227 ------------VVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 274 VVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG Sbjct: 197 RLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 256 Query: 275 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA 334 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA Sbjct: 257 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA 316 Query: 335 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM 394 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM Sbjct: 317 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM 376 Query: 395 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN 454 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN Sbjct: 377 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN 436 Query: 455 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL 514 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL Sbjct: 437 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL 496 Query: 515 HPRLISLYGGSMEEMIPK 532 HPRLISLYGGSMEEMIPK Sbjct: 497 HPRLISLYGGSMEEMIPK 514 >gi|71896711 ceramide kinase-like isoform d [Homo sapiens] Length = 463 Score = 867 bits (2241), Expect = 0.0 Identities = 449/532 (84%), Positives = 455/532 (85%), Gaps = 69/532 (12%) Query: 1 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD Sbjct: 1 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60 Query: 61 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI Sbjct: 61 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120 Query: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK Sbjct: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180 Query: 181 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDGVVCVGGDGSASEVA 240 EATQVYYEKVEPLLKLAGIKTDVT S + +A Sbjct: 181 EATQVYYEKVEPLLKLAGIKTDVT-----------------------------RSTNVLA 211 Query: 241 HALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTNVLAHSLHGVPHVITATLHIIMGH 300 H+L G +V+ +LH IIMGH Sbjct: 212 HSL-----------------------------HGVPHVITATLH-----------IIMGH 231 Query: 301 VQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAE 360 VQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAE Sbjct: 232 VQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAE 291 Query: 361 DCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQMIQGQFLNVSIMAIPCLCSVAPRGLAP 420 DCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQMIQGQFLNVSIMAIPCLCSVAPRGLAP Sbjct: 292 DCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQMIQGQFLNVSIMAIPCLCSVAPRGLAP 351 Query: 421 NTRLNNGSMALIIARNTSRPEFIKHLKRYASVKNQFNFPFVETYTVEEVKVHPRNNTGGY 480 NTRLNNGSMALIIARNTSRPEFIKHLKRYASVKNQFNFPFVETYTVEEVKVHPRNNTGGY Sbjct: 352 NTRLNNGSMALIIARNTSRPEFIKHLKRYASVKNQFNFPFVETYTVEEVKVHPRNNTGGY 411 Query: 481 NPEEEEDETASENCFPWNVDGDLMEVASEVHIRLHPRLISLYGGSMEEMIPK 532 NPEEEEDETASENCFPWNVDGDLMEVASEVHIRLHPRLISLYGGSMEEMIPK Sbjct: 412 NPEEEEDETASENCFPWNVDGDLMEVASEVHIRLHPRLISLYGGSMEEMIPK 463 >gi|71896725 ceramide kinase-like isoform c [Homo sapiens] Length = 419 Score = 533 bits (1373), Expect = e-151 Identities = 261/262 (99%), Positives = 261/262 (99%) Query: 271 IPAGSTNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRT 330 I AGSTNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRT Sbjct: 158 ILAGSTNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRT 217 Query: 331 LALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCND 390 LALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCND Sbjct: 218 LALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCND 277 Query: 391 QWQMIQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYA 450 QWQMIQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYA Sbjct: 278 QWQMIQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYA 337 Query: 451 SVKNQFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEV 510 SVKNQFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEV Sbjct: 338 SVKNQFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEV 397 Query: 511 HIRLHPRLISLYGGSMEEMIPK 532 HIRLHPRLISLYGGSMEEMIPK Sbjct: 398 HIRLHPRLISLYGGSMEEMIPK 419 Score = 326 bits (836), Expect = 3e-89 Identities = 162/164 (98%), Positives = 162/164 (98%) Query: 1 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD Sbjct: 1 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60 Query: 61 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI Sbjct: 61 VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120 Query: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPN 164 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAG N Sbjct: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGSTN 164 >gi|20336726 ceramide kinase [Homo sapiens] Length = 537 Score = 209 bits (532), Expect = 5e-54 Identities = 149/532 (28%), Positives = 256/532 (48%), Gaps = 63/532 (11%) Query: 48 LRGIFEIGRDSCDVVLSE-RALR--WRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLK 104 L+ + + + C V L RAL WR P A + + E I +++ V K Sbjct: 10 LQSVLWVKQQRCAVSLEPARALLRWWRSPGPGAGAPGADACSVPVSEIIAVEET-DVHGK 68 Query: 105 RRCSVKQQRSGTLLGITLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPN 164 + S K Q+ T+ + +++ K + + E C +W + +++L + Sbjct: 69 HQGSGKWQKMEKPYAFTVHCVKRARRHRWKWAQVTFWCPEEQLCHLWLQTLREMLEKLTS 128 Query: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224 RPK L + +NP K + ++Y KV PL LA I TD+ + E+ A L E + + Sbjct: 129 RPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETLYEINIDKY 188 Query: 225 DGVVCVGGDGSASEVAHALLLRAQKNAGMETDR---ILTPVRAQLPLGLIPAGSTNVLAH 281 DG+VCVGGDG SEV H L+ R Q++AG++ + +L P + L +G+IPAGST+ + + Sbjct: 189 DGIVCVGGDGMFSEVLHGLIGRTQRSAGVDQNHPRAVLVP--SSLRIGIIPAGSTDCVCY 246 Query: 282 SLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAM-FGFGGRTLALAEKYRWM 340 S G T+ LHI++G +DV + LLR+ S + +GF G + +EK RW+ Sbjct: 247 STVGTSDAETSALHIVVGDSLAMDVSSVHHNSTLLRYSVSLLGYGFYGDIIKDSEKKRWL 306 Query: 341 SPNQRRDFAVVKALAKLKAEDCEISFLPFNSS------------------------DDVQ 376 R DF+ +K + +SFLP + ++ Q Sbjct: 307 G-LARYDFSGLKTFLSHHCYEGTVSFLPAQHTVGSPRDRKPCRAGCFVCRQSKQQLEEEQ 365 Query: 377 ERRAQGSPKSDCNDQWQMIQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARN 436 ++ G ++ ++WQ++ G+FL ++ + C C +PRGL+P L +GS LI+ R Sbjct: 366 KKALYGLEAAEDVEEWQVVCGKFLAINATNMSCACRRSPRGLSPAAHLGDGSSDLILIRK 425 Query: 437 TSRPEFIKHLKRYASVKNQFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASE---- 492 SR F++ L R+ + ++QF+F FVE Y V++ + ++ E+ED E Sbjct: 426 CSRFNFLRFLIRHTNQQDQFDFTFVEVYRVKKFQFTSKH-------MEDEDSDLKEGGKK 478 Query: 493 ----------NC------FPWNVDGDLMEVASEVHIRLHPRLISLYGGSMEE 528 +C WN DG+++ + + +R+H +L+ L+ +EE Sbjct: 479 RFGHICSSHPSCCCTVSNSSWNCDGEVLH-SPAIEVRVHCQLVRLFARGIEE 529 >gi|8922701 acylglycerol kinase [Homo sapiens] Length = 422 Score = 69.7 bits (169), Expect = 6e-12 Identities = 43/145 (29%), Positives = 73/145 (50%), Gaps = 18/145 (12%) Query: 167 KSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDG 226 K + LNP + K +A ++ + P+L L+G+ + +YEG A LL+ ++ D Sbjct: 61 KKATVFLNPAACKGKARTLFEKNAAPILHLSGMDVTIVKTDYEGQAKKLLE--LMENTDV 118 Query: 227 VVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTNVLAHSL--- 283 ++ GGDG+ EV +L R + +++P+G IP G T+ L+H+L Sbjct: 119 IIVAGGDGTLQEVVTGVLRRTDE-----------ATFSKIPIGFIPLGETSSLSHTLFAE 167 Query: 284 --HGVPHVITATLHIIMGHVQLVDV 306 + V H+ ATL I+ G +DV Sbjct: 168 SGNKVQHITDATLAIVKGETVPLDV 192 >gi|217272885 sphingosine kinase 1 isoform 3 [Homo sapiens] Length = 384 Score = 67.8 bits (164), Expect = 2e-11 Identities = 63/214 (29%), Positives = 95/214 (44%), Gaps = 22/214 (10%) Query: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224 RP + +LLNP+ K +A Q++ V+PLL A I + + E HA L++ EL + Sbjct: 13 RPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRW 72 Query: 225 DGVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTNVLAHSLH 284 D +V + GDG EV + L+ R + Q PL +PAGS N LA SL+ Sbjct: 73 DALVVMSGDGLMHEVVNGLMERPDWETAI-----------QKPLCSLPAGSGNALAASLN 121 Query: 285 ---GVPHV------ITATLHIIMGHVQLVDVCTFSTAGKLLRFG-FSAMFGFGGRTLALA 334 G V TL + + +++ + TA L F S +GF + Sbjct: 122 HYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLES 181 Query: 335 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLP 368 EKYR + R LA L+ +++LP Sbjct: 182 EKYRRLG-EMRFTLGTFLRLAALRTYRGRLAYLP 214 >gi|217272883 sphingosine kinase 1 isoform 3 [Homo sapiens] Length = 384 Score = 67.8 bits (164), Expect = 2e-11 Identities = 63/214 (29%), Positives = 95/214 (44%), Gaps = 22/214 (10%) Query: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224 RP + +LLNP+ K +A Q++ V+PLL A I + + E HA L++ EL + Sbjct: 13 RPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRW 72 Query: 225 DGVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTNVLAHSLH 284 D +V + GDG EV + L+ R + Q PL +PAGS N LA SL+ Sbjct: 73 DALVVMSGDGLMHEVVNGLMERPDWETAI-----------QKPLCSLPAGSGNALAASLN 121 Query: 285 ---GVPHV------ITATLHIIMGHVQLVDVCTFSTAGKLLRFG-FSAMFGFGGRTLALA 334 G V TL + + +++ + TA L F S +GF + Sbjct: 122 HYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLES 181 Query: 335 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLP 368 EKYR + R LA L+ +++LP Sbjct: 182 EKYRRLG-EMRFTLGTFLRLAALRTYRGRLAYLP 214 >gi|21361088 sphingosine kinase 1 isoform 1 [Homo sapiens] Length = 398 Score = 67.8 bits (164), Expect = 2e-11 Identities = 63/214 (29%), Positives = 95/214 (44%), Gaps = 22/214 (10%) Query: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224 RP + +LLNP+ K +A Q++ V+PLL A I + + E HA L++ EL + Sbjct: 27 RPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRW 86 Query: 225 DGVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTNVLAHSLH 284 D +V + GDG EV + L+ R + Q PL +PAGS N LA SL+ Sbjct: 87 DALVVMSGDGLMHEVVNGLMERPDWETAI-----------QKPLCSLPAGSGNALAASLN 135 Query: 285 ---GVPHV------ITATLHIIMGHVQLVDVCTFSTAGKLLRFG-FSAMFGFGGRTLALA 334 G V TL + + +++ + TA L F S +GF + Sbjct: 136 HYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLES 195 Query: 335 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLP 368 EKYR + R LA L+ +++LP Sbjct: 196 EKYRRLG-EMRFTLGTFLRLAALRTYRGRLAYLP 228 >gi|217272880 sphingosine kinase 1 isoform 2 [Homo sapiens] Length = 470 Score = 67.8 bits (164), Expect = 2e-11 Identities = 63/214 (29%), Positives = 95/214 (44%), Gaps = 22/214 (10%) Query: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224 RP + +LLNP+ K +A Q++ V+PLL A I + + E HA L++ EL + Sbjct: 99 RPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRW 158 Query: 225 DGVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTNVLAHSLH 284 D +V + GDG EV + L+ R + Q PL +PAGS N LA SL+ Sbjct: 159 DALVVMSGDGLMHEVVNGLMERPDWETAI-----------QKPLCSLPAGSGNALAASLN 207 Query: 285 ---GVPHV------ITATLHIIMGHVQLVDVCTFSTAGKLLRFG-FSAMFGFGGRTLALA 334 G V TL + + +++ + TA L F S +GF + Sbjct: 208 HYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLES 267 Query: 335 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLP 368 EKYR + R LA L+ +++LP Sbjct: 268 EKYRRLG-EMRFTLGTFLRLAALRTYRGRLAYLP 300 >gi|21361699 sphingosine kinase 2 [Homo sapiens] Length = 654 Score = 66.6 bits (161), Expect = 5e-11 Identities = 58/214 (27%), Positives = 97/214 (45%), Gaps = 22/214 (10%) Query: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224 RP L +L+NP + A Q V P++ AG+ ++ E + HA L++ L + Sbjct: 179 RPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEW 238 Query: 225 DGVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTNVLAHSLH 284 DG+V V GDG EV + LL DR ++P+G++P GS N LA +++ Sbjct: 239 DGIVTVSGDGLLHEVLNGLL-----------DRPDWEEAVKMPVGILPCGSGNALAGAVN 287 Query: 285 ---------GVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGF-SAMFGFGGRTLALA 334 G+ ++ +L + G +D+ + + A F F S +GF + Sbjct: 288 QHGGFEPALGLDLLLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQS 347 Query: 335 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLP 368 E++R + + R V LA L +S+LP Sbjct: 348 ERFRALG-SARFTLGTVLGLATLHTYRGRLSYLP 380 >gi|48255900 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform a [Homo sapiens] Length = 1590 Score = 33.5 bits (75), Expect = 0.50 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 32/174 (18%) Query: 15 GGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCDVVLSERALRWRPIQ 74 GGR APP AA P A + P + A G+ S + L ++ R PIQ Sbjct: 284 GGRPSPAPPAAAQPPAAAVPGPSVPQPAP-----------GQPSPVLQLQQKQSRISPIQ 332 Query: 75 PERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGITLFICLKKEQNKLK 134 +P G ++L + E+ +L+ R + + Q L G K +LK Sbjct: 333 --KPQGLDPVEILQEREY---------RLQARIAHRIQELENLPGSLPPDLRTKATVELK 381 Query: 135 NSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKKEATQVYYE 188 L L+N RQ ++ + R +L+ LN +++K+ Q E Sbjct: 382 --ALRLLNFQ--------RQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLRE 425 >gi|48255898 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform b [Homo sapiens] Length = 1572 Score = 33.5 bits (75), Expect = 0.50 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 32/174 (18%) Query: 15 GGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCDVVLSERALRWRPIQ 74 GGR APP AA P A + P + A G+ S + L ++ R PIQ Sbjct: 284 GGRPSPAPPAAAQPPAAAVPGPSVPQPAP-----------GQPSPVLQLQQKQSRISPIQ 332 Query: 75 PERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGITLFICLKKEQNKLK 134 +P G ++L + E+ +L+ R + + Q L G K +LK Sbjct: 333 --KPQGLDPVEILQEREY---------RLQARIAHRIQELENLPGSLPPDLRTKATVELK 381 Query: 135 NSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKKEATQVYYE 188 L L+N RQ ++ + R +L+ LN +++K+ Q E Sbjct: 382 --ALRLLNFQ--------RQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLRE 425 >gi|39930469 brix domain containing 1 [Homo sapiens] Length = 306 Score = 31.6 bits (70), Expect = 1.9 Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 7/106 (6%) Query: 118 LGITLFICLKKEQN-KLKNSTLDLINLSEDHCDIW--FRQFKKILAGFPNRPKSLKILLN 174 LGI F+ LK +N K T ++ + D D+ +R+ K +L F P I L Sbjct: 119 LGIENFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLA 178 Query: 175 PQSHKKEAT----QVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLL 216 + T ++Y+ + LLK +G +T +E G +L L+ Sbjct: 179 GLEYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLV 224 >gi|4502897 cleft lip and palate associated transmembrane protein 1 [Homo sapiens] Length = 669 Score = 31.6 bits (70), Expect = 1.9 Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 2/84 (2%) Query: 373 DDVQERRAQGSPKSDCNDQWQMIQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALI 432 D E + Q P + WQ+I+G + I I + S RG AP + G + Sbjct: 34 DPPAETQPQNPPAQPAPNAWQVIKGVLFRIFI--IWAISSWFRRGPAPQDQAGPGGAPRV 91 Query: 433 IARNTSRPEFIKHLKRYASVKNQF 456 +RN + + +L Y S F Sbjct: 92 ASRNLFPKDTLMNLHVYISEHEHF 115 >gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo sapiens] Length = 1487 Score = 30.4 bits (67), Expect = 4.2 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 7/69 (10%) Query: 3 WRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCDVV 62 W RR G E E PP AA +L+ +P + ++ + RG E +DS D Sbjct: 945 WNRR-------PGNEERELPPAAAIGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEK 997 Query: 63 LSERALRWR 71 WR Sbjct: 998 SDRNRPWWR 1006 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 30.4 bits (67), Expect = 4.2 Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 4/74 (5%) Query: 7 RNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCDVVLSER 66 R R S PPE PPA T P E E + +G+ I R D V Sbjct: 444 RERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAV---- 499 Query: 67 ALRWRPIQPERPAG 80 ++ P+ P+G Sbjct: 500 SIEILPVAVATPSG 513 >gi|7661950 SH2 domain binding protein 1 [Homo sapiens] Length = 1173 Score = 30.0 bits (66), Expect = 5.5 Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 16/80 (20%) Query: 155 FKKILAGFPNRPKSLKILLN-------------PQSHKKEATQVYYEKVEPLLKLAGI-- 199 F+K+L +PN +++KIL + + H K+ T+ Y + VE ++LA I Sbjct: 364 FEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILE 423 Query: 200 KTDVT-IMEYEGHALSLLKE 218 +TD+ + G A +L+E Sbjct: 424 QTDIQGALSAYGTATRILQE 443 >gi|55743118 RAB3 GTPase-activating protein [Homo sapiens] Length = 981 Score = 29.6 bits (65), Expect = 7.2 Identities = 27/103 (26%), Positives = 39/103 (37%), Gaps = 5/103 (4%) Query: 156 KKILAGFPNRPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAG-----IKTDVTIMEYEG 210 KKI+ + + NP+ K E VE L+ A T+ E E Sbjct: 805 KKIIKQIISHSSKVLHFPNPEDKKLEEIIHQITNVEALIARARSLKAKFGTEKCEQEEEK 864 Query: 211 HALSLLKECELQGFDGVVCVGGDGSASEVAHALLLRAQKNAGM 253 L C L+ + +V G G A + H L + AQ+ A M Sbjct: 865 EDLERFVSCLLEQPEVLVTGAGRGHAGRIIHKLFVNAQRAAAM 907 >gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo sapiens] Length = 513 Score = 29.6 bits (65), Expect = 7.2 Identities = 27/146 (18%), Positives = 61/146 (41%), Gaps = 12/146 (8%) Query: 92 FIELKDIFSVKLKRRCSVKQQRSGTLLG-ITLFICLKKEQNKLKNSTLDLINLSEDHCDI 150 FIE+ + + K+++ + Q + ++ L +C ++ L D + Sbjct: 237 FIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQD------GKIKV 290 Query: 151 WFRQFKKILAGFPN-RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYE 209 W Q + L F K + L S K+++Q+ + +++ G+K+ T+ E+ Sbjct: 291 WKIQSGQCLRRFERAHSKGVTCL----SFSKDSSQILSASFDQTIRIHGLKSGKTLKEFR 346 Query: 210 GHALSLLKECELQGFDGVVCVGGDGS 235 GH+ + + Q ++ DG+ Sbjct: 347 GHSSFVNEATFTQDGHYIISASSDGT 372 >gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens] Length = 450 Score = 29.3 bits (64), Expect = 9.4 Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 14 EGGREEEAPPEAAAVPPALLTSPQQTEAAAERIL--LRGIFEIGR 56 E EEE P+A V PA SP + R+L LRG +GR Sbjct: 303 EEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGR 347 >gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens] Length = 3661 Score = 29.3 bits (64), Expect = 9.4 Identities = 11/36 (30%), Positives = 21/36 (58%) Query: 183 TQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKE 218 +++YY K+ P LK G+ DV+ ++ H + + E Sbjct: 2250 SELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLE 2285 >gi|11055976 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 [Homo sapiens] Length = 395 Score = 29.3 bits (64), Expect = 9.4 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 8/69 (11%) Query: 1 MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSC- 59 +PWRR + + R +PP +A P ++S EA + + R F + R++C Sbjct: 111 LPWRRNLSDLFQWAVSRALCSPPACSAFPRGAISS----EAVCKPLCARQSFTLAREACR 166 Query: 60 ---DVVLSE 65 VVL E Sbjct: 167 SYSHVVLKE 175 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,662,807 Number of Sequences: 37866 Number of extensions: 930597 Number of successful extensions: 2756 Number of sequences better than 10.0: 24 Number of HSP's better than 10.0 without gapping: 15 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 2725 Number of HSP's gapped (non-prelim): 30 length of query: 532 length of database: 18,247,518 effective HSP length: 107 effective length of query: 425 effective length of database: 14,195,856 effective search space: 6033238800 effective search space used: 6033238800 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.