Guide to the Human Genome
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Search of human proteins with 41393187

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41393187 NADPH oxidase activator 1 [Homo sapiens]
         (483 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41393187 NADPH oxidase activator 1 [Homo sapiens]                 1001   0.0  
gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens]             196   4e-50
gi|67189970 neutrophil cytosolic factor 2 [Homo sapiens]              196   4e-50
gi|52421790 mitogen-activated protein kinase kinase kinase 9 [Ho...    55   1e-07
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H...    53   7e-07
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H...    53   7e-07
gi|155723000 mixed lineage kinase 4 [Homo sapiens]                     51   2e-06
gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo s...    50   5e-06
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ...    49   8e-06
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ...    49   8e-06
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ...    49   8e-06
gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ...    49   8e-06
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ...    49   8e-06
gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ...    49   8e-06
gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo s...    49   8e-06
gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo ...    49   8e-06
gi|5729856 GRB2-related adaptor protein [Homo sapiens]                 48   2e-05
gi|222446607 SH3 domain containing ring finger 2 [Homo sapiens]        47   4e-05
gi|21735550 mitogen-activated protein kinase kinase kinase 10 [H...    47   4e-05
gi|4505195 mitogen-activated protein kinase kinase kinase 11 [Ho...    45   2e-04
gi|39930351 dynamin binding protein [Homo sapiens]                     44   3e-04
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                44   4e-04
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                44   4e-04
gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]                44   4e-04
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]         42   0.001
gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]         42   0.001
gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]         42   0.001
gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 ...    42   0.001
gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [...    42   0.001
gi|55956916 myosin IE [Homo sapiens]                                   41   0.003

>gi|41393187 NADPH oxidase activator 1 [Homo sapiens]
          Length = 483

 Score = 1001 bits (2587), Expect = 0.0
 Identities = 483/483 (100%), Positives = 483/483 (100%)

Query: 1   MASLGDLVRAWHLGAQAVDRGDWARALHLFSGVPAPPARLCFNAGCVHLLAGDPEAALRA 60
           MASLGDLVRAWHLGAQAVDRGDWARALHLFSGVPAPPARLCFNAGCVHLLAGDPEAALRA
Sbjct: 1   MASLGDLVRAWHLGAQAVDRGDWARALHLFSGVPAPPARLCFNAGCVHLLAGDPEAALRA 60

Query: 61  FDQAVTKDTCMAVGFFQRGVANFQLARFQEALSDFWLALEQLRGHAAIDYTQLGLRFKLQ 120
           FDQAVTKDTCMAVGFFQRGVANFQLARFQEALSDFWLALEQLRGHAAIDYTQLGLRFKLQ
Sbjct: 61  FDQAVTKDTCMAVGFFQRGVANFQLARFQEALSDFWLALEQLRGHAAIDYTQLGLRFKLQ 120

Query: 121 AWEVLHNVASAQCQLGLWTEAASSLREAMSKWPEGSLNGLDSALDQVQRRGSLPPRQVPR 180
           AWEVLHNVASAQCQLGLWTEAASSLREAMSKWPEGSLNGLDSALDQVQRRGSLPPRQVPR
Sbjct: 121 AWEVLHNVASAQCQLGLWTEAASSLREAMSKWPEGSLNGLDSALDQVQRRGSLPPRQVPR 180

Query: 181 GEVFRPHRWHLKHLEPVDFLGKAKVVASAIPDDQGWGVRPQQPQGPGANHDARSLIMDSP 240
           GEVFRPHRWHLKHLEPVDFLGKAKVVASAIPDDQGWGVRPQQPQGPGANHDARSLIMDSP
Sbjct: 181 GEVFRPHRWHLKHLEPVDFLGKAKVVASAIPDDQGWGVRPQQPQGPGANHDARSLIMDSP 240

Query: 241 RAGTHQGPLDAETEVGADRCTSTAYQEQRPQVEQVGKQAPLSPGLPAMGGPGPGPCEDPA 300
           RAGTHQGPLDAETEVGADRCTSTAYQEQRPQVEQVGKQAPLSPGLPAMGGPGPGPCEDPA
Sbjct: 241 RAGTHQGPLDAETEVGADRCTSTAYQEQRPQVEQVGKQAPLSPGLPAMGGPGPGPCEDPA 300

Query: 301 GAGGAGAGGSEPLVTVTVQCAFTVALRARRGADLSSLRALLGQALPHQAQLGQLSYLAPG 360
           GAGGAGAGGSEPLVTVTVQCAFTVALRARRGADLSSLRALLGQALPHQAQLGQLSYLAPG
Sbjct: 301 GAGGAGAGGSEPLVTVTVQCAFTVALRARRGADLSSLRALLGQALPHQAQLGQLSYLAPG 360

Query: 361 EDGHWVPIPEEESLQRAWQDAAACPRGLQLQCRGAGGRPVLYQVVAQHSYSAQGPEDLGF 420
           EDGHWVPIPEEESLQRAWQDAAACPRGLQLQCRGAGGRPVLYQVVAQHSYSAQGPEDLGF
Sbjct: 361 EDGHWVPIPEEESLQRAWQDAAACPRGLQLQCRGAGGRPVLYQVVAQHSYSAQGPEDLGF 420

Query: 421 RQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGPRMSGAPGRLPRSQQG 480
           RQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGPRMSGAPGRLPRSQQG
Sbjct: 421 RQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGPRMSGAPGRLPRSQQG 480

Query: 481 DQP 483
           DQP
Sbjct: 481 DQP 483


>gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens]
          Length = 526

 Score =  196 bits (498), Expect = 4e-50
 Identities = 161/528 (30%), Positives = 241/528 (45%), Gaps = 88/528 (16%)

Query: 3   SLGDLVRAWHLGAQAVDRGDWARALHLFSGVPAPPARLCFNAGCVHLLAGDPEAALRAFD 62
           SL + +  W+ G  A D+ DW  AL  FS V  P +R+CFN GC++ +  +   A +AF 
Sbjct: 2   SLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAFT 61

Query: 63  QAVTKDTCMAVGFFQRGVANFQLARFQEALSDFWLALEQLRGHAAIDYTQLGLRFKLQAW 122
           +++ +D  +AV +FQRG+  +Q  ++  A+ D   AL QLRG+  IDY  LGL+FKL A 
Sbjct: 62  RSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFAC 121

Query: 123 EVLHNVASAQCQLGLWTEAASSLREAMSKWPEGSLNGLDSALDQVQRRGSLPPRQVPRGE 182
           EVL+N+A    +   W +A   L  A S   E   + +D A++ V ++    P  +P G+
Sbjct: 122 EVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVGK 181

Query: 183 VFRPHRWHLKHLEPVDFLGKAKVVASAIPDDQGWGVRPQQPQG------PGANHDARSLI 236
           +FRP+   +  L   D+LGKA VVAS +  D   G  P QPQ       P      R+L 
Sbjct: 182 LFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRALE 241

Query: 237 MDSPRA------------GTHQGPLDAETEVGADRCTSTAYQEQR--------------- 269
            ++ R                 G +    + G D   +  +  Q+               
Sbjct: 242 GEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRI 301

Query: 270 -PQVEQVGKQAPLS----------PGLPAMGGPGPGPCEDPAGAGGAGAGGSEPL-VTVT 317
            PQ +   + +P S          PG P +  PG    E+P          S P+  T+ 
Sbjct: 302 HPQQQPQEESSPQSDIPAPPSSKAPGRPQL-SPGQKQKEEP-----KEVKLSVPMPYTLK 355

Query: 318 VQCAFTVALRARRGADLSSLRALLGQALPHQAQLGQLSYLAPGEDGHWVPIPEEESLQRA 377
           V   +TV ++ + G   S +R ++ + L  + +  +LSY  P +    VP+  E+S++ A
Sbjct: 356 VHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSY-RPRDSNELVPL-SEDSMKDA 413

Query: 378 W-QDAAACPRGLQLQCRGAGG---------------------RPVL---YQVVAQHSYSA 412
           W Q    C   L L C    G                      P L    QV A  SY A
Sbjct: 414 WGQVKNYC---LTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEA 470

Query: 413 QGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
             PEDL F++GD + VL +       V++ WLEG C G++GIFPK FV
Sbjct: 471 TQPEDLEFQEGDIILVLSK-------VNEEWLEGECKGKVGIFPKVFV 511


>gi|67189970 neutrophil cytosolic factor 2 [Homo sapiens]
          Length = 526

 Score =  196 bits (498), Expect = 4e-50
 Identities = 161/528 (30%), Positives = 241/528 (45%), Gaps = 88/528 (16%)

Query: 3   SLGDLVRAWHLGAQAVDRGDWARALHLFSGVPAPPARLCFNAGCVHLLAGDPEAALRAFD 62
           SL + +  W+ G  A D+ DW  AL  FS V  P +R+CFN GC++ +  +   A +AF 
Sbjct: 2   SLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAFT 61

Query: 63  QAVTKDTCMAVGFFQRGVANFQLARFQEALSDFWLALEQLRGHAAIDYTQLGLRFKLQAW 122
           +++ +D  +AV +FQRG+  +Q  ++  A+ D   AL QLRG+  IDY  LGL+FKL A 
Sbjct: 62  RSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFAC 121

Query: 123 EVLHNVASAQCQLGLWTEAASSLREAMSKWPEGSLNGLDSALDQVQRRGSLPPRQVPRGE 182
           EVL+N+A    +   W +A   L  A S   E   + +D A++ V ++    P  +P G+
Sbjct: 122 EVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVGK 181

Query: 183 VFRPHRWHLKHLEPVDFLGKAKVVASAIPDDQGWGVRPQQPQG------PGANHDARSLI 236
           +FRP+   +  L   D+LGKA VVAS +  D   G  P QPQ       P      R+L 
Sbjct: 182 LFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRALE 241

Query: 237 MDSPRA------------GTHQGPLDAETEVGADRCTSTAYQEQR--------------- 269
            ++ R                 G +    + G D   +  +  Q+               
Sbjct: 242 GEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRI 301

Query: 270 -PQVEQVGKQAPLS----------PGLPAMGGPGPGPCEDPAGAGGAGAGGSEPL-VTVT 317
            PQ +   + +P S          PG P +  PG    E+P          S P+  T+ 
Sbjct: 302 HPQQQPQEESSPQSDIPAPPSSKAPGRPQL-SPGQKQKEEP-----KEVKLSVPMPYTLK 355

Query: 318 VQCAFTVALRARRGADLSSLRALLGQALPHQAQLGQLSYLAPGEDGHWVPIPEEESLQRA 377
           V   +TV ++ + G   S +R ++ + L  + +  +LSY  P +    VP+  E+S++ A
Sbjct: 356 VHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSY-RPRDSNELVPL-SEDSMKDA 413

Query: 378 W-QDAAACPRGLQLQCRGAGG---------------------RPVL---YQVVAQHSYSA 412
           W Q    C   L L C    G                      P L    QV A  SY A
Sbjct: 414 WGQVKNYC---LTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEA 470

Query: 413 QGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
             PEDL F++GD + VL +       V++ WLEG C G++GIFPK FV
Sbjct: 471 TQPEDLEFQEGDIILVLSK-------VNEEWLEGECKGKVGIFPKVFV 511


>gi|52421790 mitogen-activated protein kinase kinase kinase 9 [Homo
           sapiens]
          Length = 1118

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 43/121 (35%), Positives = 60/121 (49%), Gaps = 14/121 (11%)

Query: 346 PHQAQLGQLSYLA----PGEDGHWVPIPEEESLQRAWQDAAACPRGLQLQCRGAGGRPVL 401
           P +A LG L+  A    PGEDG      EEE  +   ++AAA     +L C      P+ 
Sbjct: 3   PSRALLGCLASAAAAAPPGEDGAGAGAEEEEEEE---EEAAAAVGPGELGCDA----PLP 55

Query: 402 YQVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVV 461
           Y   A   Y A G ++L  R GD V+VL ++  V  + D+ W  G  + R+GIFP  +V 
Sbjct: 56  YWT-AVFEYEAAGEDELTLRLGDVVEVLSKDSQV--SGDEGWWTGQLNQRVGIFPSNYVT 112

Query: 462 P 462
           P
Sbjct: 113 P 113


>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
           sapiens]
          Length = 756

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 26/67 (38%), Positives = 38/67 (56%), Gaps = 7/67 (10%)

Query: 399 PVLYQVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKC 458
           P +Y+V+    Y  + P++L  R+GD V VL +  +     D+ W EG C GR G+FP  
Sbjct: 183 PEVYRVL--FDYQPEAPDELALRRGDVVKVLSKTTE-----DKGWWEGECQGRRGVFPDN 235

Query: 459 FVVPAGP 465
           FV+P  P
Sbjct: 236 FVLPPPP 242



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 10/76 (13%)

Query: 409 SYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV--VPAGPR 466
           SYS +  ++L  + G+ V+++ E       ++  W  G  +G++G FP  FV  + +GP 
Sbjct: 93  SYSPEQADELKLQAGEIVEMIKE-------IEDGWWLGKKNGQLGAFPSNFVELLDSGPP 145

Query: 467 MSGAPGRLPRSQQGDQ 482
             G P  +P    G Q
Sbjct: 146 SLGNPD-MPSVSPGPQ 160



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 9/76 (11%)

Query: 403 QVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV-- 460
           +V+    Y AQ  ++L    GD V  +   P       + WL G   GR G+FP+  V  
Sbjct: 2   EVLVLAGYRAQKEDELSLAPGDVVRQVRWVPA------RGWLRGEFGGRYGLFPERLVQE 55

Query: 461 VPAGPRMSGAPGRLPR 476
           +P   R SG   R PR
Sbjct: 56  IPETLRGSG-EARRPR 70


>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
           sapiens]
          Length = 645

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 26/67 (38%), Positives = 38/67 (56%), Gaps = 7/67 (10%)

Query: 399 PVLYQVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKC 458
           P +Y+V+    Y  + P++L  R+GD V VL +  +     D+ W EG C GR G+FP  
Sbjct: 72  PEVYRVL--FDYQPEAPDELALRRGDVVKVLSKTTE-----DKGWWEGECQGRRGVFPDN 124

Query: 459 FVVPAGP 465
           FV+P  P
Sbjct: 125 FVLPPPP 131


>gi|155723000 mixed lineage kinase 4 [Homo sapiens]
          Length = 1036

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 25/66 (37%), Positives = 37/66 (56%), Gaps = 2/66 (3%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGP 465
           A + Y A+G ++L  R+G  V+VL +  D  ++ D+ W  G    R+GIFP  +V P  P
Sbjct: 45  ALYDYEARGEDELSLRRGQLVEVLSQ--DAAVSGDEGWWAGQVQRRLGIFPANYVAPCRP 102

Query: 466 RMSGAP 471
             S AP
Sbjct: 103 AASPAP 108


>gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo
           sapiens]
          Length = 486

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 12/102 (11%)

Query: 359 PGEDGHWVPIPEEESLQRAWQDAAACPRGLQLQCRGAGGRPVLYQVVAQHSYSAQGPEDL 418
           P  D   V  PE+ S   A   ++ CP G      GAG   +    VA + Y  +G ++L
Sbjct: 393 PEGDYEEVLEPEDSSFSSALAGSSGCPAGA-----GAGAVALGISAVALYDYQGEGSDEL 447

Query: 419 GFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
            F   D +       D+ + VD+ W  G C G  G+FP  +V
Sbjct: 448 SFDPDDVIT------DIEM-VDEGWWRGRCHGHFGLFPANYV 482


>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
           sapiens]
          Length = 492

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 7/74 (9%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGP 465
           A + + AQ  ++L F++GDTV +L +       +DQ W EG   GR+GIFP  +V    P
Sbjct: 262 AVYDFKAQTSKELSFKKGDTVYILRK-------IDQNWYEGEHHGRVGIFPISYVEKLTP 314

Query: 466 RMSGAPGRLPRSQQ 479
                P R P   Q
Sbjct: 315 PEKAQPARPPPPAQ 328


>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
           sapiens]
          Length = 1004

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 7/74 (9%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGP 465
           A + + AQ  ++L F++GDTV +L +       +DQ W EG   GR+GIFP  +V    P
Sbjct: 774 AVYDFKAQTSKELSFKKGDTVYILRK-------IDQNWYEGEHHGRVGIFPISYVEKLTP 826

Query: 466 RMSGAPGRLPRSQQ 479
                P R P   Q
Sbjct: 827 PEKAQPARPPPPAQ 840


>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
           sapiens]
          Length = 824

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 7/74 (9%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGP 465
           A + + AQ  ++L F++GDTV +L +       +DQ W EG   GR+GIFP  +V    P
Sbjct: 594 AVYDFKAQTSKELSFKKGDTVYILRK-------IDQNWYEGEHHGRVGIFPISYVEKLTP 646

Query: 466 RMSGAPGRLPRSQQ 479
                P R P   Q
Sbjct: 647 PEKAQPARPPPPAQ 660


>gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo
           sapiens]
          Length = 661

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 7/74 (9%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGP 465
           A + + AQ  ++L F++GDTV +L +       +DQ W EG   GR+GIFP  +V    P
Sbjct: 431 AVYDFKAQTSKELSFKKGDTVYILRK-------IDQNWYEGEHHGRVGIFPISYVEKLTP 483

Query: 466 RMSGAPGRLPRSQQ 479
                P R P   Q
Sbjct: 484 PEKAQPARPPPPAQ 497


>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
           sapiens]
          Length = 731

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 7/74 (9%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGP 465
           A + + AQ  ++L F++GDTV +L +       +DQ W EG   GR+GIFP  +V    P
Sbjct: 501 AVYDFKAQTSKELSFKKGDTVYILRK-------IDQNWYEGEHHGRVGIFPISYVEKLTP 553

Query: 466 RMSGAPGRLPRSQQ 479
                P R P   Q
Sbjct: 554 PEKAQPARPPPPAQ 567


>gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 644

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 7/74 (9%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGP 465
           A + + AQ  ++L F++GDTV +L +       +DQ W EG   GR+GIFP  +V    P
Sbjct: 414 AVYDFKAQTSKELSFKKGDTVYILRK-------IDQNWYEGEHHGRVGIFPISYVEKLTP 466

Query: 466 RMSGAPGRLPRSQQ 479
                P R P   Q
Sbjct: 467 PEKAQPARPPPPAQ 480


>gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 1100

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 7/74 (9%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGP 465
           A + + AQ  ++L F++GDTV +L +       +DQ W EG   GR+GIFP  +V    P
Sbjct: 870 AVYDFKAQTSKELSFKKGDTVYILRK-------IDQNWYEGEHHGRVGIFPISYVEKLTP 922

Query: 466 RMSGAPGRLPRSQQ 479
                P R P   Q
Sbjct: 923 PEKAQPARPPPPAQ 936


>gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 666

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 7/74 (9%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGP 465
           A + + AQ  ++L F++GDTV +L +       +DQ W EG   GR+GIFP  +V    P
Sbjct: 436 AVYDFKAQTSKELSFKKGDTVYILRK-------IDQNWYEGEHHGRVGIFPISYVEKLTP 488

Query: 466 RMSGAPGRLPRSQQ 479
                P R P   Q
Sbjct: 489 PEKAQPARPPPPAQ 502


>gi|5729856 GRB2-related adaptor protein [Homo sapiens]
          Length = 217

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 25/57 (43%), Positives = 32/57 (56%), Gaps = 7/57 (12%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVP 462
           AQ  +SAQ P  L FR+GD ++VL E P      D  W  G   GR+G FP+ +V P
Sbjct: 165 AQFDFSAQDPSQLSFRRGDIIEVL-ERP------DPHWWRGRSCGRVGFFPRSYVQP 214


>gi|222446607 SH3 domain containing ring finger 2 [Homo sapiens]
          Length = 729

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 28/69 (40%), Positives = 38/69 (55%), Gaps = 9/69 (13%)

Query: 405 VAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEG--HCDGRIGIFPKCFVVP 462
           VA HSYSA GP++L  ++G+ V VL +  D        WL G     GR+GIFP  +V+P
Sbjct: 386 VALHSYSAHGPDELDLQKGEGVRVLGKCQD-------GWLRGVSLVTGRVGIFPNNYVIP 438

Query: 463 AGPRMSGAP 471
              + S  P
Sbjct: 439 IFRKTSSFP 447



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 401 LYQVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
           LY    +    ++  + L F + D + V+         VD+ W EG    ++GIFP  FV
Sbjct: 195 LYNFDLRGKDKSENQDCLTFLKDDIITVISR-------VDENWAEGKLGDKVGIFPILFV 247

Query: 461 VP 462
            P
Sbjct: 248 EP 249



 Score = 29.3 bits (64), Expect = 8.3
 Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 7/48 (14%)

Query: 409 SYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFP 456
           +Y  Q P DL F +GD + +  +       +D+ W +G  +G  G FP
Sbjct: 135 NYRGQNPGDLRFNKGDIILLRRQ-------LDENWYQGEINGISGNFP 175


>gi|21735550 mitogen-activated protein kinase kinase kinase 10 [Homo
           sapiens]
          Length = 954

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 6/75 (8%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHC-DGRIGIFPKCFVVPAG 464
           A   Y A G E+L  R+GD V VL +  D  ++ D+ W  G    GR+G+FP  +V P  
Sbjct: 23  AVFDYEAAGDEELTLRRGDRVQVLSQ--DCAVSGDEGWWTGQLPSGRVGVFPSNYVAPGA 80

Query: 465 PRMSGAPGRLPRSQQ 479
           P    AP  L   Q+
Sbjct: 81  P---AAPAGLQLPQE 92


>gi|4505195 mitogen-activated protein kinase kinase kinase 11 [Homo
           sapiens]
          Length = 847

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 11/80 (13%)

Query: 394 GAGGRPVLYQVVAQHS---------YSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWL 444
           G GGRP      A ++         Y   G ++L  R+GD V+VL    D  ++ D+ W 
Sbjct: 27  GGGGRPEGSPKAAGYANPVWTALFDYEPSGQDELALRKGDRVEVLSR--DAAISGDEGWW 84

Query: 445 EGHCDGRIGIFPKCFVVPAG 464
            G   G++GIFP  +V   G
Sbjct: 85  AGQVGGQVGIFPSNYVSRGG 104


>gi|39930351 dynamin binding protein [Homo sapiens]
          Length = 1577

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 26/63 (41%), Positives = 34/63 (53%), Gaps = 7/63 (11%)

Query: 403 QVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVP 462
           Q  A    SAQ  E+L FR+GD + ++     VP   +  W EG  +GR GIFP+ FV  
Sbjct: 149 QARALMGLSAQLDEELDFREGDVITII----GVP---EPGWFEGELEGRRGIFPEGFVEL 201

Query: 463 AGP 465
            GP
Sbjct: 202 LGP 204



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 7/56 (12%)

Query: 405 VAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
           VA + + A  P +L F  GD + +L         ++  WLEG   GR GIFP  FV
Sbjct: 249 VALYRFQALEPNELDFEVGDKIRILA-------TLEDGWLEGSLKGRTGIFPYRFV 297


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 19/58 (32%), Positives = 34/58 (58%), Gaps = 7/58 (12%)

Query: 403  QVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
            QV+  + Y+AQ  ++L F +G  ++VL +E       D  W +G  +G++G+FP  +V
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKE-------DPDWWKGEVNGQVGLFPSNYV 1209



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 8/71 (11%)

Query: 403  QVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVP 462
            + +A ++Y +    DL F+QGD + V  ++ D        W  G    + G+FP  +V  
Sbjct: 1006 EFIAMYTYESSEQGDLTFQQGDVILVTKKDGD--------WWTGTVGDKAGVFPSNYVRL 1057

Query: 463  AGPRMSGAPGR 473
                 SG  G+
Sbjct: 1058 KDSEGSGTAGK 1068



 Score = 32.3 bits (72), Expect = 0.99
 Identities = 28/88 (31%), Positives = 37/88 (42%), Gaps = 15/88 (17%)

Query: 396  GGRPVLYQVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGR---- 451
            G +P + QV+A  SY+A GPE L    G  + +  + P         W EG    R    
Sbjct: 1073 GKKPEIAQVIA--SYTATGPEQLTLAPGQLILIRKKNPG-------GWWEGELQARGKKR 1123

Query: 452  -IGIFPKCFVVPAGPRMSG-APGRLPRS 477
             IG FP  +V    P  S   P   P+S
Sbjct: 1124 QIGWFPANYVKLLSPGTSKITPTEPPKS 1151



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 5/88 (5%)

Query: 369 PEEESLQRAWQDAAACPRGLQLQCRGAGGRPVLYQVVAQHSYSAQGPEDLGFRQGDTVDV 428
           P + ++Q  W  A   P  +  Q      + V Y+  A + + ++  +++  + GD V V
Sbjct: 715 PAKPAVQAPWSTAEKGPLTISAQ---ENVKVVYYR--ALYPFESRSHDEITIQPGDIVMV 769

Query: 429 LCEEPDVPLAVDQAWLEGHCDGRIGIFP 456
             E  D     +  WL G   G+ G FP
Sbjct: 770 KGEWVDESQTGEPGWLGGELKGKTGWFP 797


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 19/58 (32%), Positives = 34/58 (58%), Gaps = 7/58 (12%)

Query: 403  QVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
            QV+  + Y+AQ  ++L F +G  ++VL +E       D  W +G  +G++G+FP  +V
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKE-------DPDWWKGEVNGQVGLFPSNYV 1209



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 8/71 (11%)

Query: 403  QVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVP 462
            + +A ++Y +    DL F+QGD + V  ++ D        W  G    + G+FP  +V  
Sbjct: 1006 EFIAMYTYESSEQGDLTFQQGDVILVTKKDGD--------WWTGTVGDKAGVFPSNYVRL 1057

Query: 463  AGPRMSGAPGR 473
                 SG  G+
Sbjct: 1058 KDSEGSGTAGK 1068



 Score = 32.3 bits (72), Expect = 0.99
 Identities = 28/88 (31%), Positives = 37/88 (42%), Gaps = 15/88 (17%)

Query: 396  GGRPVLYQVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGR---- 451
            G +P + QV+A  SY+A GPE L    G  + +  + P         W EG    R    
Sbjct: 1073 GKKPEIAQVIA--SYTATGPEQLTLAPGQLILIRKKNPG-------GWWEGELQARGKKR 1123

Query: 452  -IGIFPKCFVVPAGPRMSG-APGRLPRS 477
             IG FP  +V    P  S   P   P+S
Sbjct: 1124 QIGWFPANYVKLLSPGTSKITPTEPPKS 1151



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 5/88 (5%)

Query: 369 PEEESLQRAWQDAAACPRGLQLQCRGAGGRPVLYQVVAQHSYSAQGPEDLGFRQGDTVDV 428
           P + ++Q  W  A   P  +  Q      + V Y+  A + + ++  +++  + GD V V
Sbjct: 715 PAKPAVQAPWSTAEKGPLTISAQ---ENVKVVYYR--ALYPFESRSHDEITIQPGDIVMV 769

Query: 429 LCEEPDVPLAVDQAWLEGHCDGRIGIFP 456
             E  D     +  WL G   G+ G FP
Sbjct: 770 KGEWVDESQTGEPGWLGGELKGKTGWFP 797


>gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]
          Length = 690

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 28/96 (29%), Positives = 39/96 (40%), Gaps = 8/96 (8%)

Query: 385 PRGLQLQCRGAGGRPVLYQVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWL 444
           P   Q      G  P  +   A +SY+ Q  E+L F +G  + +L    D    VD  + 
Sbjct: 532 PESSQDSDNPCGAEPTAFLAQALYSYTGQSAEELSFPEGALIRLLPRAQD---GVDDGFW 588

Query: 445 EGHCDGRIGIFPKCFV-----VPAGPRMSGAPGRLP 475
            G   GR+G+FP   V      P  P +S     LP
Sbjct: 589 RGEFGGRVGVFPSLLVEELLGPPGPPELSDPEQMLP 624


>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
          Length = 731

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 7/74 (9%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGP 465
           A HS++A+  +DL F++GD + +L         +D  W  G    R GIFP  FV P   
Sbjct: 609 ALHSFTAETSDDLSFKRGDRIQIL-------ERLDSDWCRGRLQDREGIFPAVFVRPCPA 661

Query: 466 RMSGAPGRLPRSQQ 479
                   +P+ ++
Sbjct: 662 EAKSMLAIVPKGRK 675



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 7/56 (12%)

Query: 405 VAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
           V  H + A+  +DL    G+ V +L +       +D  W  G+C  +IGIFP  +V
Sbjct: 442 VVLHDFPAEQVDDLNLTSGEIVYLLEK-------IDTDWYRGNCRNQIGIFPANYV 490



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 7/58 (12%)

Query: 405 VAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVP 462
           VA+  Y  +  ++L F +G+ + +L E       V++ W  G   GR GIFP  FV P
Sbjct: 518 VARFEYIGEQKDELSFSEGEII-ILKEY------VNEEWARGEVRGRTGIFPLNFVEP 568



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 16/55 (29%), Positives = 28/55 (50%), Gaps = 7/55 (12%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
           A + +  +  ++L F+ GD +  L        +VD  W+ G   G+ GIFPK ++
Sbjct: 678 ALYDFRGENEDELSFKAGDIITEL-------ESVDDDWMSGELMGKSGIFPKNYI 725


>gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]
          Length = 767

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 7/74 (9%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGP 465
           A HS++A+  +DL F++GD + +L         +D  W  G    R GIFP  FV P   
Sbjct: 645 ALHSFTAETSDDLSFKRGDRIQIL-------ERLDSDWCRGRLQDREGIFPAVFVRPCPA 697

Query: 466 RMSGAPGRLPRSQQ 479
                   +P+ ++
Sbjct: 698 EAKSMLAIVPKGRK 711



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 7/56 (12%)

Query: 405 VAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
           V  H + A+  +DL    G+ V +L +       +D  W  G+C  +IGIFP  +V
Sbjct: 478 VVLHDFPAEQVDDLNLTSGEIVYLLEK-------IDTDWYRGNCRNQIGIFPANYV 526



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 7/58 (12%)

Query: 405 VAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVP 462
           VA+  Y  +  ++L F +G+ + +L E       V++ W  G   GR GIFP  FV P
Sbjct: 554 VARFEYIGEQKDELSFSEGEII-ILKEY------VNEEWARGEVRGRTGIFPLNFVEP 604



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 16/55 (29%), Positives = 28/55 (50%), Gaps = 7/55 (12%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
           A + +  +  ++L F+ GD +  L        +VD  W+ G   G+ GIFPK ++
Sbjct: 714 ALYDFRGENEDELSFKAGDIITEL-------ESVDDDWMSGELMGKSGIFPKNYI 761


>gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]
          Length = 790

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 7/74 (9%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGP 465
           A HS++A+  +DL F++GD + +L         +D  W  G    R GIFP  FV P   
Sbjct: 668 ALHSFTAETSDDLSFKRGDRIQIL-------ERLDSDWCRGRLQDREGIFPAVFVRPCPA 720

Query: 466 RMSGAPGRLPRSQQ 479
                   +P+ ++
Sbjct: 721 EAKSMLAIVPKGRK 734



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 7/56 (12%)

Query: 405 VAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
           V  H + A+  +DL    G+ V +L +       +D  W  G+C  +IGIFP  +V
Sbjct: 501 VVLHDFPAEQVDDLNLTSGEIVYLLEK-------IDTDWYRGNCRNQIGIFPANYV 549



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 7/58 (12%)

Query: 405 VAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVP 462
           VA+  Y  +  ++L F +G+ + +L E       V++ W  G   GR GIFP  FV P
Sbjct: 577 VARFEYIGEQKDELSFSEGEII-ILKEY------VNEEWARGEVRGRTGIFPLNFVEP 627



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 16/55 (29%), Positives = 28/55 (50%), Gaps = 7/55 (12%)

Query: 406 AQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
           A + +  +  ++L F+ GD +  L        +VD  W+ G   G+ GIFPK ++
Sbjct: 737 ALYDFRGENEDELSFKAGDIITEL-------ESVDDDWMSGELMGKSGIFPKNYI 784


>gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1
           [Homo sapiens]
          Length = 878

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 5/65 (7%)

Query: 400 VLYQVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCF 459
           V+   VA+++++A+   +L  R+GD V +        +  DQ W +G  +GRIG FP  +
Sbjct: 817 VIGTAVARYNFAARDMRELSLREGDVVRIYSR-----IGGDQGWWKGETNGRIGWFPSTY 871

Query: 460 VVPAG 464
           V   G
Sbjct: 872 VEEEG 876


>gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2
           [Homo sapiens]
          Length = 839

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 5/65 (7%)

Query: 400 VLYQVVAQHSYSAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCF 459
           V+   VA+++++A+   +L  R+GD V +        +  DQ W +G  +GRIG FP  +
Sbjct: 778 VIGTAVARYNFAARDMRELSLREGDVVRIYSR-----IGGDQGWWKGETNGRIGWFPSTY 832

Query: 460 VVPAG 464
           V   G
Sbjct: 833 VEEEG 837


>gi|55956916 myosin IE [Homo sapiens]
          Length = 1108

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 15/90 (16%)

Query: 379  QDAAACPRGLQLQCRGAGGRPV--------LYQVVAQHSYSAQGPEDLGFRQGDTVDVLC 430
            Q AA   R    +   AGGRP         + Q  A ++Y AQ  ++L F   D +D++ 
Sbjct: 1023 QGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIK 1082

Query: 431  EEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
            E+P         W  G   G+ G+FP  +V
Sbjct: 1083 EDP-------SGWWTGRLRGKQGLFPNNYV 1105


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,390,725
Number of Sequences: 37866
Number of extensions: 1214648
Number of successful extensions: 6831
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 213
Number of HSP's that attempted gapping in prelim test: 6317
Number of HSP's gapped (non-prelim): 663
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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