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Search of human proteins with 41350201
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41350201 epsin 1 isoform c [Homo sapiens]
(550 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41350201 epsin 1 isoform c [Homo sapiens] 1136 0.0
gi|194272148 epsin 1 isoform a [Homo sapiens] 1131 0.0
gi|194248095 epsin 1 isoform b [Homo sapiens] 1117 0.0
gi|156671217 epsin 2 isoform a [Homo sapiens] 487 e-137
gi|157388929 epsin 3 [Homo sapiens] 415 e-116
gi|156671215 epsin 2 isoform b [Homo sapiens] 409 e-114
gi|31377575 ENTH domain containing 1 [Homo sapiens] 211 1e-54
gi|156671219 epsin 2 isoform c [Homo sapiens] 188 1e-47
gi|7661968 epsin 4 [Homo sapiens] 169 5e-42
gi|163965366 nascent polypeptide-associated complex alpha subuni... 89 8e-18
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 82 1e-15
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 76 7e-14
gi|110832843 TBP-associated factor 4 [Homo sapiens] 75 2e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 73 8e-13
gi|210032580 SET domain containing 1B [Homo sapiens] 72 1e-12
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] 72 1e-12
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 71 2e-12
gi|116284392 mucin 2 precursor [Homo sapiens] 70 4e-12
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 70 4e-12
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 70 7e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 69 9e-12
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 69 1e-11
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 69 1e-11
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 69 1e-11
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 69 1e-11
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 68 2e-11
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 68 2e-11
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 68 2e-11
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 68 2e-11
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 68 2e-11
>gi|41350201 epsin 1 isoform c [Homo sapiens]
Length = 550
Score = 1136 bits (2938), Expect = 0.0
Identities = 550/550 (100%), Positives = 550/550 (100%)
Query: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
Sbjct: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
Query: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
Sbjct: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
Query: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 180
VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
Sbjct: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 180
Query: 181 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT 240
SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT
Sbjct: 181 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT 240
Query: 241 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA 300
APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA
Sbjct: 241 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA 300
Query: 301 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK 360
PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK
Sbjct: 301 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK 360
Query: 361 PSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRG 420
PSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRG
Sbjct: 361 PSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRG 420
Query: 421 SLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLP 480
SLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLP
Sbjct: 421 SLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLP 480
Query: 481 GGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGP 540
GGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGP
Sbjct: 481 GGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGP 540
Query: 541 PAPNTNPFLL 550
PAPNTNPFLL
Sbjct: 541 PAPNTNPFLL 550
>gi|194272148 epsin 1 isoform a [Homo sapiens]
Length = 662
Score = 1131 bits (2926), Expect = 0.0
Identities = 550/551 (99%), Positives = 550/551 (99%), Gaps = 1/551 (0%)
Query: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
Sbjct: 112 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 171
Query: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
Sbjct: 172 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 231
Query: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 180
VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
Sbjct: 232 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 291
Query: 181 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT 240
SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT
Sbjct: 292 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT 351
Query: 241 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA 300
APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA
Sbjct: 352 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA 411
Query: 301 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK 360
PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK
Sbjct: 412 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK 471
Query: 361 PSTNGTT-AGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR 419
PSTNGTT AGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR
Sbjct: 472 PSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR 531
Query: 420 GSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL 479
GSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL
Sbjct: 532 GSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL 591
Query: 480 PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG 539
PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG
Sbjct: 592 PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG 651
Query: 540 PPAPNTNPFLL 550
PPAPNTNPFLL
Sbjct: 652 PPAPNTNPFLL 662
>gi|194248095 epsin 1 isoform b [Homo sapiens]
Length = 576
Score = 1117 bits (2890), Expect = 0.0
Identities = 550/576 (95%), Positives = 550/576 (95%), Gaps = 26/576 (4%)
Query: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
Sbjct: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
Query: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
Sbjct: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
Query: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 180
VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
Sbjct: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 180
Query: 181 SGEEELQLQLALAMSKEEADQ-------------------------EERIRRGDDLRLQM 215
SGEEELQLQLALAMSKEEADQ EERIRRGDDLRLQM
Sbjct: 181 SGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQM 240
Query: 216 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 275
AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP
Sbjct: 241 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 300
Query: 276 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV 335
VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV
Sbjct: 301 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV 360
Query: 336 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTT-AGGFDTEPDEFSDFDRLRTALPTSGSS 394
SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTT AGGFDTEPDEFSDFDRLRTALPTSGSS
Sbjct: 361 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS 420
Query: 395 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 454
AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA
Sbjct: 421 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 480
Query: 455 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 514
LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP
Sbjct: 481 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 540
Query: 515 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 550
VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
Sbjct: 541 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 576
>gi|156671217 epsin 2 isoform a [Homo sapiens]
Length = 584
Score = 487 bits (1254), Expect = e-137
Identities = 305/635 (48%), Positives = 366/635 (57%), Gaps = 136/635 (21%)
Query: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
M+TSS+RRQMKNIV+NYSEAEIKVREATSNDPWGPSSSLM+EIADLTYNVVAFSEIMSM+
Sbjct: 1 MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMV 60
Query: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
WKRLNDHGKNWRHVYKA+TL++YLIKTGSERV+QQC+EN++A+QTLKDFQY+DRDGKDQG
Sbjct: 61 WKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG 120
Query: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSA-----AVGSGPP----- 170
+NVREK+KQLVALL+DE+RL+ ERA ALKTKE++AQ AT + GS P
Sbjct: 121 INVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTS 180
Query: 171 -------------------------PEAEQAWPQSSGEEELQLQLALAMSKEEADQEERI 205
E EQA PQ+SGEEELQLQLALAMS+E A+QEER+
Sbjct: 181 HSEQEYGKAGGSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERL 240
Query: 206 RRGDDLRLQMAIEESKRET----GGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAV 261
RRGDDLRLQMA+EES+R+T KE SL + P++ P
Sbjct: 241 RRGDDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSGP----------- 289
Query: 262 PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW-----RPAAPAGPSVDPWG-GTPAP 315
AA ++PWG +PWGGPA ++ DPW +PAA S+DPWG T A
Sbjct: 290 --AAQKAEPWGPSASTNQTNPWGGPAAPASTSDPWPSFGTKPAA----SIDPWGVPTGAT 343
Query: 316 AAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFD--- 372
DPW +S +G ASD W S KP + +G F+
Sbjct: 344 VQSVPKNSDPWAASQQPASSAGKRASDAWGAV---------STTKPV---SVSGSFELFS 391
Query: 373 ----TEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGS 428
T D+FS+FD LRT+ T+ S +P+++ G S
Sbjct: 392 NLNGTIKDDFSEFDNLRTSKKTAES--------VTSLPSQNNGTTSPDPFESQPLTVASS 443
Query: 429 PPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGP 488
P +A RKTPESFLGPNAALV+LDSLV+RP P A++ NPFL G PAT
Sbjct: 444 KPSSA--------RKTPESFLGPNAALVNLDSLVTRPAPP---AQSLNPFLAPGAPATSA 492
Query: 489 SVTNPFQPAPPATLTLNQLRLSPV--------------------------PPVPGAPPTY 522
V NPFQ P LTLNQLR SPV P GA +
Sbjct: 493 PV-NPFQVNQPQPLTLNQLRGSPVLGTSTSFGPGPGVESMAVASMTSAAPQPALGATGSS 551
Query: 523 ISPLG-------GGPGLPPMMPPGPPAPNTNPFLL 550
++PLG G G+PP TNPFLL
Sbjct: 552 LTPLGPAMMNMVGSVGIPP--SAAQATGTTNPFLL 584
>gi|157388929 epsin 3 [Homo sapiens]
Length = 632
Score = 415 bits (1066), Expect = e-116
Identities = 288/672 (42%), Positives = 355/672 (52%), Gaps = 163/672 (24%)
Query: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
M+TS+LRRQ+KNIVHNYSEAEIKVREATSNDPWGP SSLMSEIADLT+N VAF+E+M M+
Sbjct: 1 MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGML 60
Query: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
W+RLND GKNWRHVYKA+TL++YL+KTGSERV+ QC+EN+Y +QTLKDFQY+DRDGKDQG
Sbjct: 61 WRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQG 120
Query: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLA-----------------------QT 157
VNVREK KQ++ALL+DE+RLR+ER HALKTKE++A
Sbjct: 121 VNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSR 180
Query: 158 ATASSAAVGSGPP---PEAEQAWPQSSGEEELQLQLALAMSKEEADQ--EERIRRGDDLR 212
+ SS S P + EQA PQ+SGEEELQLQLALAMS+EEA++ R +DL+
Sbjct: 181 GSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQ 240
Query: 213 LQMAI----------------------------------EESKRETGGKEE------SSL 232
LQ+A+ E +RE +EE SS+
Sbjct: 241 LQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSI 300
Query: 233 MDLADVFTAPAPAPTT----DPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAP 288
+DLAD+F P+T DPW P P + WG P+ADPW P P
Sbjct: 301 LDLADIFVPALAPPSTHCSADPWDIP----GFRPNTEASGSSWG-----PSADPW-SPIP 350
Query: 289 TP---ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWT 345
+ + PW P S +PWG TP AG PT DPW ++ P P T
Sbjct: 351 SGTVLSRSQPW-DLTPMLSSSEPWGRTPVLPAGP-PTTDPWA-------LNSPHHKLPST 401
Query: 346 PAPAFSDPWGGSPAKPSTNG--TTAGGFDTEPDEFSDFDRLRTALPT-SGSSAGELELLA 402
A DPWG S T G +T F P+ + L ALP+ SS EL+L
Sbjct: 402 GA----DPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFG 457
Query: 403 GEVPA------RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNA-AL 455
P+ + P A D+ G L EA+ P A +TPESFLGP+A +L
Sbjct: 458 DPSPSSKQNGTKEPDALDL----GILGEALTQPSKEARAC------RTPESFLGPSASSL 507
Query: 456 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL-SPVPP 514
V+LDSLV P AK NPFL G + PS TNPF P TLNQ+R SP
Sbjct: 508 VNLDSLVK----APQVAKTRNPFLTG---LSAPSPTNPFGAGEPGRPTLNQMRTGSPALG 560
Query: 515 VPGAP--------------PTYISPLGGGPGLP---------------PMMP-------- 537
+ G P P +S + G LP P++P
Sbjct: 561 LAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPR 620
Query: 538 PGPPAPNTNPFL 549
P PP TNPFL
Sbjct: 621 PPPPQTGTNPFL 632
>gi|156671215 epsin 2 isoform b [Homo sapiens]
Length = 641
Score = 409 bits (1050), Expect = e-114
Identities = 282/680 (41%), Positives = 350/680 (51%), Gaps = 169/680 (24%)
Query: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
M+TSS+RRQMKNIV+NYSEAEIKVREATSNDPWGPSSSLM+EIADLTYNVVAFSEIMSM+
Sbjct: 1 MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMV 60
Query: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
WKRLNDHGKNWRHVYKA+TL++YLIKTGSERV+QQC+EN++A+QTLKDFQY+DRDGKDQG
Sbjct: 61 WKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG 120
Query: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSA-----AVGSGPP----P 171
+NVREK+KQLVALL+DE+RL+ ERA ALKTKE++AQ AT + GS P
Sbjct: 121 INVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTS 180
Query: 172 EAEQAWPQSSG-------------------------EEELQ---------LQLALAMSKE 197
+EQ + ++ G EELQ L LA S+
Sbjct: 181 HSEQEYGKAGGSPASYHGSPEASLCPQHRTGAPLGQSEELQPLSQRHPFLPHLGLA-SRP 239
Query: 198 EADQE------ERIRRGDDLRLQMAIEESKRETGGKEESSL------------------- 232
D +R R R+ +E+++ +T G+EE L
Sbjct: 240 NGDWSQPCLTCDRAARATSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERLRR 299
Query: 233 -------MDLADVFTAPAPAPTTDPWGGPAPMAA------AVPTAAPT---SDPWGGPPV 276
M L + P G A+P++ P ++PWG
Sbjct: 300 GDDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSGPAAQKAEPWGPSAS 359
Query: 277 PPAADPWGGPAPTPASGDPW-----RPAAPAGPSVDPWG-GTPAPAAGEGPTPDPWGSSD 330
+PWGGPA ++ DPW +PAA S+DPWG T A DPW +S
Sbjct: 360 TNQTNPWGGPAAPASTSDPWPSFGTKPAA----SIDPWGVPTGATVQSVPKNSDPWAASQ 415
Query: 331 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFD-------TEPDEFSDFDR 383
+G ASD W S KP + +G F+ T D+FS+FD
Sbjct: 416 QPASSAGKRASDAWGAV---------STTKPV---SVSGSFELFSNLNGTIKDDFSEFDN 463
Query: 384 LRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRK 443
LRT+ T+ S +P+++ G S P +A RK
Sbjct: 464 LRTSKKTAES--------VTSLPSQNNGTTSPDPFESQPLTVASSKPSSA--------RK 507
Query: 444 TPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT 503
TPESFLGPNAALV+LDSLV+RP P A++ NPFL G PAT V NPFQ P LT
Sbjct: 508 TPESFLGPNAALVNLDSLVTRPAPP---AQSLNPFLAPGAPATSAPV-NPFQVNQPQPLT 563
Query: 504 LNQLRLSPV--------------------------PPVPGAPPTYISPLG-------GGP 530
LNQLR SPV P GA + ++PLG G
Sbjct: 564 LNQLRGSPVLGTSTSFGPGPGVESMAVASMTSAAPQPALGATGSSLTPLGPAMMNMVGSV 623
Query: 531 GLPPMMPPGPPAPNTNPFLL 550
G+PP TNPFLL
Sbjct: 624 GIPP--SAAQATGTTNPFLL 641
>gi|31377575 ENTH domain containing 1 [Homo sapiens]
Length = 607
Score = 211 bits (538), Expect = 1e-54
Identities = 98/163 (60%), Positives = 129/163 (79%)
Query: 5 SLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRL 64
+ RRQ+KN V NYS+AEIKVREATSNDPWGPSSSLM +I+DLT+N ++ SEIM+M+W RL
Sbjct: 2 AFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRL 61
Query: 65 NDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVR 124
NDHGKNWRHVYK++TLM+YLIK GS++V Q C+E +QTLKDFQ++D GKDQG +R
Sbjct: 62 NDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIR 121
Query: 125 EKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGS 167
EK+KQ++ LL DE L +ER A +T+++ + + S +GS
Sbjct: 122 EKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSKRQLGS 164
>gi|156671219 epsin 2 isoform c [Homo sapiens]
Length = 356
Score = 188 bits (477), Expect = 1e-47
Identities = 148/407 (36%), Positives = 186/407 (45%), Gaps = 101/407 (24%)
Query: 194 MSKEEADQEERIRRGDDLRLQMAIEESKRET----GGKEESSLMDLADVFTAPAPAPTTD 249
MS+E A+QEER+RRGDDLRLQMA+EES+R+T KE SL + P++
Sbjct: 1 MSREVAEQEERLRRGDDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSG 60
Query: 250 PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW-----RPAAPAGP 304
P AA ++PWG +PWGGPA ++ DPW +PAA
Sbjct: 61 P-------------AAQKAEPWGPSASTNQTNPWGGPAAPASTSDPWPSFGTKPAA---- 103
Query: 305 SVDPWG-GTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPST 363
S+DPWG T A DPW +S +G ASD W S KP
Sbjct: 104 SIDPWGVPTGATVQSVPKNSDPWAASQQPASSAGKRASDAWGAV---------STTKPV- 153
Query: 364 NGTTAGGFD-------TEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMS 416
+ +G F+ T D+FS+FD LRT+ T+ S +P+++ G
Sbjct: 154 --SVSGSFELFSNLNGTIKDDFSEFDNLRTSKKTAES--------VTSLPSQNNGTTSPD 203
Query: 417 GVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASN 476
S P +A RKTPESFLGPNAALV+LDSLV+RP P A++ N
Sbjct: 204 PFESQPLTVASSKPSSA--------RKTPESFLGPNAALVNLDSLVTRPAPP---AQSLN 252
Query: 477 PFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPV------------------------ 512
PFL G PAT V NPFQ P LTLNQLR SPV
Sbjct: 253 PFLAPGAPATSAPV-NPFQVNQPQPLTLNQLRGSPVLGTSTSFGPGPGVESMAVASMTSA 311
Query: 513 --PPVPGAPPTYISPLG-------GGPGLPPMMPPGPPAPNTNPFLL 550
P GA + ++PLG G G+PP TNPFLL
Sbjct: 312 APQPALGATGSSLTPLGPAMMNMVGSVGIPP--SAAQATGTTNPFLL 356
>gi|7661968 epsin 4 [Homo sapiens]
Length = 625
Score = 169 bits (429), Expect = 5e-42
Identities = 86/175 (49%), Positives = 118/175 (67%), Gaps = 4/175 (2%)
Query: 12 NIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKR-LNDHGKN 70
N+V NYSE E KVREAT++DPWGPS LM EIA T+ F E+M+M+W R L D+ KN
Sbjct: 16 NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKN 75
Query: 71 WRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQL 130
WR VYK++ L+ YLI+ GSERV +E++Y +++L+++ +VD GKDQG+N+R+K K+L
Sbjct: 76 WRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKEL 135
Query: 131 VALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEE 185
V +D+DRLREER A K K+K SS +VG E P+S +EE
Sbjct: 136 VEFAQDDDRLREERKKAKKNKDKY---VGVSSDSVGGFRYSERYDPEPKSKWDEE 187
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 89.4 bits (220), Expect = 8e-18
Identities = 107/365 (29%), Positives = 125/365 (34%), Gaps = 71/365 (19%)
Query: 240 TAPA---PAPTTDPWGGPAPMAAAVPTAAPTSDPWGGP---------PVPPAA---DPWG 284
T PA P+P P P P A+ P AA P G P P PAA P G
Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069
Query: 285 GPAPTPASGDPWRPAAP-----AGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPS 339
GPA G P PAA GP+ G P P A P+P GG+ + P
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK------GGL-ATPPH 1122
Query: 340 ASDPWTPAPAFSDPWGGSPAKPSTNGTTA---------GGFDTEPDEFSDFDRLRTALPT 390
P TPA P GG P T GG T P + + T
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 391 SGSSAGELELLAGEVPARSP----GAFDMSGVRGSLAEAVGSPPPA----ATPTP----T 438
G A A PA +P G +G+ +PP ATP+P T
Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1242
Query: 439 PPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAK----------ASNPFL-----PGGG 483
P P GP A + P TPP K A NP + P GG
Sbjct: 1243 TPAATPPSPKGGP--ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 484 PATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAP-PTYISPLG--GGPGLPPMMPPGP 540
PAT P P PPA + PP GAP P ++P G P LP P
Sbjct: 1301 PATSPP---KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357
Query: 541 PAPNT 545
P T
Sbjct: 1358 GGPTT 1362
Score = 89.4 bits (220), Expect = 8e-18
Identities = 114/363 (31%), Positives = 130/363 (35%), Gaps = 70/363 (19%)
Query: 242 PAPAPTT------DPWGGPAPMA---AAVPTAAPTSDPWGGP--------PVPPAADPWG 284
P APTT P GGPA + A P AA P GGP P+PPAA P
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP-- 1110
Query: 285 GPAPTPASGDPWRPAAPAGPSVDP----WGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSA 340
P+P P AP P+ P G P G TP S G + P
Sbjct: 1111 -PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169
Query: 341 SDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEF------SDFDRLRTALPTSGSS 394
P TPA P GG A PS G T P S T T S
Sbjct: 1170 GAPTTPAATPPSPKGGL-ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1228
Query: 395 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTP---TPPTRK----TPES 447
G L + + +P A S G +PPP PTP TPP+ K TP
Sbjct: 1229 KGGLATPSPKGAPTTPAATPPSPKGGP-----ATPPPKGAPTPPAATPPSLKGGLATPPH 1283
Query: 448 FLGPNAALVDLDSLVSRPGPTPP-GA---KASNPFLPGGGPATGPSVTNPFQPA-----P 498
PN A+V S P +PP GA A+ P P G P T P P PA P
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
Query: 499 PATLTLNQLRLSPVPPVPGAPPTYISPLGGGP--------GLPPMMPPGP------PAPN 544
T TL + P G P T S G P G P M PP P P+P
Sbjct: 1344 KGTPTLP----ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399
Query: 545 TNP 547
+P
Sbjct: 1400 GDP 1402
Score = 87.0 bits (214), Expect = 4e-17
Identities = 106/371 (28%), Positives = 136/371 (36%), Gaps = 86/371 (23%)
Query: 240 TAPAPAPTTDPWGG---PAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPAS---- 292
T PA P + P GG P P A AA P GG PP PA TP S
Sbjct: 1127 TTPAATPPS-PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185
Query: 293 ----GDPWRPAAPAGPSVDPWGGTPAPAAGEGPT------PDPWGS----SDGGVPVSGP 338
P PA P GG P+ PT P P G S G P + P
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT-P 1244
Query: 339 SASDPWTPAPAFSDPWGGSPAKPS-TNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGE 397
+A+ P + P G+P P+ T + GG T P + + + T G A
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304
Query: 398 LELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTP---TPPTRK--------TPE 446
A PA +P + +GS G+PPP PTP TPP+ K TP
Sbjct: 1305 PPKGAPTPPAATPPS-----PKGS----PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 447 SFLGPNAALVDLDSLVSRPGPTPPGAKASN---PFLPGGGPATGPSVTNPF-QPAPPATL 502
S GP S+ GPTPP A S+ P + P GP++ +P P PA +
Sbjct: 1356 SKGGPTTPS-------SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
Query: 503 TLNQLRLSPVPPV---------------PGAPPTYI-------SPLGG--------GPGL 532
L+ + +P PV P P + +P GG P L
Sbjct: 1409 PLSPKK-APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Query: 533 PPMMPPGPPAP 543
P + PP P P
Sbjct: 1468 PAVTPPSPKEP 1478
Score = 80.5 bits (197), Expect = 4e-15
Identities = 94/330 (28%), Positives = 118/330 (35%), Gaps = 60/330 (18%)
Query: 240 TAPAPAPTTDPWGG---PAPMAAAVPTAAPTSDPWGGP--------PVPPAADP---WGG 285
T PA P + P GG P+P A AA P GGP P PPAA P GG
Sbjct: 1219 TTPAATPPS-PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277
Query: 286 PAPTPASGDP-----WRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSA 340
A P G P P+ GP+ P G P P A P+P G P + P
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPK-------GSPGTPPPK 1330
Query: 341 SDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSS-AGELE 399
P PA P G+P P+T ++ GG PT+ SS G
Sbjct: 1331 GAPTPPAVTPPSP-KGTPTLPATTPSSKGG------------------PTTPSSKEGPTP 1371
Query: 400 LLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLD 459
A P S RG + P + P P +K P + + A
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP-KKAPATPVTREGAATPSK 1430
Query: 460 SLVSRPGPTPPG-AKASNPFLPGGGPATG--------PSVTNPF---QPAPPATLTLNQL 507
++ P TP KA P GGPAT P+VT P PAP T +
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490
Query: 508 RLSPVPPVPGAPPTYISPLGGGPGLPPMMP 537
+ +P P P PT + + P P P
Sbjct: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPATP 1520
Score = 79.0 bits (193), Expect = 1e-14
Identities = 99/333 (29%), Positives = 113/333 (33%), Gaps = 50/333 (15%)
Query: 241 APAPAPTTDPWGGPAPMAAAVPT--AAPTSDPWGGPPVPPAA---DPWGGPA-PTPASGD 294
AP AP A A P P S G P PPAA P GGPA P+P
Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP---- 959
Query: 295 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPD-PWGSSDGGVPVSGPSASDPWTPAPAFSDP 353
W P PA P GG P+ PTP S G P + P PA P
Sbjct: 960 KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP 1019
Query: 354 WGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAF 413
G A P G + T P P +A L A PA +
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPS------------PKGSPAATPLPKGAPTTPAAT---- 1063
Query: 414 DMSGVRGSLA--EAVGSP-PPAATPTPTP---PTRKTPESFLGPNAAL--VDLDSLVSRP 465
+ +G A G+P PPAATP P+P P +P+ P AA L + P
Sbjct: 1064 -LPSPKGGPATPSLKGAPTPPAATP-PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
Query: 466 GPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSP---VPPVPGAPPTY 522
P A+ P P GG AT P P PA L P P P A P
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP- 1180
Query: 523 ISPLG--------GGPGLPPMMPPGPPAPNTNP 547
SP G G P P PP P P
Sbjct: 1181 -SPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212
Score = 52.8 bits (125), Expect = 8e-07
Identities = 105/378 (27%), Positives = 131/378 (34%), Gaps = 91/378 (24%)
Query: 240 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAA-DPWGGPAP-----TPASG 293
++P AP T PAPM A A S P P P + DP A TPA+
Sbjct: 1488 SSPKKAPAT-----PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL 1542
Query: 294 DPWRPAAPAGPSVDPWGGTPA-PAAGEGPT----------PDPWGSSDGGVP-------- 334
P P +V TPA P E P P S+ G P
Sbjct: 1543 APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP 1602
Query: 335 --VSGPSASDPWTPAPAFSDPWGGS-PAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTS 391
V+ PS + TP PA + P PA P+ GT T P D PTS
Sbjct: 1603 PAVTSPSPKEAPTP-PAVTPPSPEKGPATPAPKGTPTSPPVT-PSSLKDS-------PTS 1653
Query: 392 GSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPES---- 447
+S + VP S G G +L E + +P P +TP T PTRK P++
Sbjct: 1654 PASV--TCKMGATVPQASKGLPAKKGPT-ALKEVLVAPAPESTPIITAPTRKGPQTKKSS 1710
Query: 448 ---------------FLGPNAALVDL----------------DSLVSRPGP-TPPGAKAS 475
GP + + D+ S GP PP +KAS
Sbjct: 1711 ATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAS 1770
Query: 476 NPFLPGGGPATGP---SVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGL 532
P P S + P+PP +L L SPVP +P P P PGL
Sbjct: 1771 TPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP---SPVPTLP--PKQQFLP--SSPGL 1823
Query: 533 PPMMPPGPPAPNTNPFLL 550
P P AP LL
Sbjct: 1824 VLESPSKPLAPADEDELL 1841
Score = 51.2 bits (121), Expect = 2e-06
Identities = 89/336 (26%), Positives = 112/336 (33%), Gaps = 39/336 (11%)
Query: 228 EESSLMDLADVFTAPAPAPTT-DPWGGPAPMAAAV-PTAAPTSDPWGGPPVPPAADPWGG 285
+E +L L V TA P P AP+A V P S P P +PPA P G
Sbjct: 691 KEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVP--SPSLPPAGTPPGT 748
Query: 286 PAPTPASGDPWRPAAPAGPSVDPW--GGTPAPAAGEGP------TPDPWG---SSDGGVP 334
S + P P G A A+ +G +P P G S P
Sbjct: 749 KKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP 808
Query: 335 VSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSS 394
+ ++ P TP S P SP + S + F D + T PT S
Sbjct: 809 PTKKGSAGPDTPIGNLSSPV--SPVEASFLPENSLSFQGSKDSPAT-----THSPTPPSP 861
Query: 395 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRK-TPESFLGPNA 453
G A +P A +G +P P+ P P TP P
Sbjct: 862 KG----------APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPAL 911
Query: 454 ALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSP-- 511
++ +R P P G AS P G P T P+ T P PAT + P
Sbjct: 912 SMTSSSPKKARATPAPKGIPASPS--PKGAP-TPPAATPPSPKGGPATPSPKWAPTPPAA 968
Query: 512 VPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNP 547
PP P P SP G P P PP P P
Sbjct: 969 TPPSPKGGPATPSP-KGAPTPPAATPPSPKGGPATP 1003
Score = 41.2 bits (95), Expect = 0.002
Identities = 71/302 (23%), Positives = 107/302 (35%), Gaps = 23/302 (7%)
Query: 259 AAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAG 318
AA PT PP+ ++ P PT + P AP PS P +
Sbjct: 450 AAAPTTTFEVATCVSPPM--SSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSP 507
Query: 319 EGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDT----- 373
P P+ + V V P+ D T PA + G+P P+ G T T
Sbjct: 508 PLPDPEDLKNLPSSVLVKFPTQKDLQT-VPASLE---GAPFSPAQAGLTTKKDPTVLPLV 563
Query: 374 --EPDEFSDFDRLRTA--LPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSP 429
P F ++ +P S + + L +P P + S + + + +V
Sbjct: 564 QAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKT 623
Query: 430 PPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPS 489
A P P K+ S + P A L+S G P AK ++ + P +
Sbjct: 624 DSYAGPDSAGPLLKS--SLITPTVAAFPLES-ADPAGVAPTTAKGTSTYTTTASPFLEGT 680
Query: 490 VTNPFQPAPPATLTLNQLRLSPVP----PVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 545
V+ + P TL L L P PV +P +PL L P +P P+P+
Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPL-ATLVLAPEIPKSVPSPSL 739
Query: 546 NP 547
P
Sbjct: 740 PP 741
Score = 34.3 bits (77), Expect = 0.30
Identities = 79/330 (23%), Positives = 116/330 (35%), Gaps = 39/330 (11%)
Query: 241 APAPAPTT---DPWGGPAPMAA---AVPTA----APTSDP-WGGPPVPPAADPWGGP--A 287
+P P+P+T P P P ++ A+P APT P GPP+ PAA P A
Sbjct: 65 SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIA 124
Query: 288 P----TPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSA-SD 342
P TP+S P A A SV P P P S + +S P A S+
Sbjct: 125 PTLKGTPSSSAPLALVALAPHSVQKSSAFP-PNLLTSPPSVAVAESGSVITLSAPIAPSE 183
Query: 343 PWT-----PAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEF-SDFDRLRTALPT-----S 391
P T P+ +P G+P+ P T T S L PT +
Sbjct: 184 PKTNLNKVPSEVVPNP-KGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIA 242
Query: 392 GSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGP 451
+ + + + ++PG+ + G V P + T + P + + GP
Sbjct: 243 SPQVKDTTISSVLISPQNPGSLSLKG-------PVSPPAALSLSTQSLPVVTSSQKTAGP 295
Query: 452 NAALVDLDSLVSRPGPTPPGAKASNPFLPGGGP-ATGPSVTNPFQPAPPATLTLNQLRLS 510
N SL S P + S L GP A +T + S
Sbjct: 296 NTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRS 355
Query: 511 PVPPVPGAPPTYISPLGGGPGLPPMMPPGP 540
+PP+P + + P + P + GP
Sbjct: 356 VIPPLPSRNEVVPATVAAFPVVAPSVDKGP 385
Score = 33.9 bits (76), Expect = 0.40
Identities = 32/133 (24%), Positives = 50/133 (37%), Gaps = 13/133 (9%)
Query: 421 SLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLP 480
S+ A+G P P P +P ++ P S + ++ S P P +S LP
Sbjct: 33 SVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALP 92
Query: 481 GG----GPATGPSVTNPFQPAPPATLTLNQLRLSPV---PPVPGAPPTYIS----PLGGG 529
G P P++ P P PA L L ++P P AP ++ +
Sbjct: 93 LGTAPEAPTFLPNLIGP--PISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKS 150
Query: 530 PGLPPMMPPGPPA 542
PP + PP+
Sbjct: 151 SAFPPNLLTSPPS 163
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 82.0 bits (201), Expect = 1e-15
Identities = 91/326 (27%), Positives = 122/326 (37%), Gaps = 42/326 (12%)
Query: 242 PAPAPTTDPWG-GPA-PMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDP--WR 297
PA P+ DP+G PA P+ PTA PT P+ P PA P G + P +G P +
Sbjct: 2168 PAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFH 2227
Query: 298 PAAPAGP-----SVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSD 352
P P + DP+ P+ P+ G V G AS+P P F +
Sbjct: 2228 TTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG-------VGGGKASEPLLSPPPFGE 2280
Query: 353 PWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEV--PARSP 410
K G ++ + F D P+SG+ G LEL +V +P
Sbjct: 2281 SRKALEVKKEELGASSPSYGPPNLGFVD-------SPSSGTHLGGLELKTPDVFKAPLTP 2333
Query: 411 GAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRK---TPESFLGPNAALVDLDSLVSRPGP 467
A + L PPPA P+PP+ P S+ P A L RP P
Sbjct: 2334 RASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ----PPLTPRPQP 2389
Query: 468 TPPGAKASNP--FLPGGG----PATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPT 521
PP + + P LP PA+ S ++ P P L+ SPV P +P
Sbjct: 2390 PPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDP 2449
Query: 522 Y----ISPLGGGPGLPPMMPPGPPAP 543
Y P P P PP P P
Sbjct: 2450 YSRPPSRPQSRDPFAPLHKPPRPQPP 2475
Score = 60.1 bits (144), Expect = 5e-09
Identities = 84/321 (26%), Positives = 114/321 (35%), Gaps = 68/321 (21%)
Query: 243 APAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPA 302
+P P P P P ++P S P PP P P+PA P P A
Sbjct: 495 SPPPEESPLSPP-------PESSPFSPLEESPLSPPEESP-----PSPALETPLSPPPEA 542
Query: 303 GPSVDPWGGTP-APAAGEGPTPDPWGSS-----DGGVPVSGPSASDPWTPAPAFS---DP 353
P P+ +P +P E PT P +S P+S P P +P P S P
Sbjct: 543 SPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602
Query: 354 WGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAF 413
+ SP P + + P E S R + P S P SP +
Sbjct: 603 FEESPLSPPPEESPL----SPPPEAS-----RLSPPPEDSP-------MSPPPEESPMSP 646
Query: 414 DMSGVRGSLAEAVG--SPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPG 471
R S V SPPP +P +PP ++P S P P
Sbjct: 647 PPEVSRLSPLPVVSRLSPPPEESPL-SPPPEESPTS-------------------PPPEA 686
Query: 472 AKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPG 531
++ S P P P + P +P P P +L L SP+ P+P P + P GP
Sbjct: 687 SRLSPP--PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP--QLCPRSEGPH 742
Query: 532 LPPM-----MPPGPPAPNTNP 547
L P + P P P+ +P
Sbjct: 743 LSPRPEEPHLSPRPEEPHLSP 763
Score = 50.8 bits (120), Expect = 3e-06
Identities = 75/291 (25%), Positives = 97/291 (33%), Gaps = 40/291 (13%)
Query: 274 PPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGV 333
P +PP + P P + P A+ P + +P P A P
Sbjct: 439 PLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEES------ 492
Query: 334 PVSGPSASDPWTPAPAFS--DPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTS 391
P+S P P +P P S P SP P + +T + L S
Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEES 552
Query: 392 GSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPP--TRKTP---E 446
S EL P + S + E+ SPPP +P PP +R P E
Sbjct: 553 PLSPPPEELPTSPPP-------EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605
Query: 447 SFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQ 506
S L P L P P ++ S P P P + P +P P PP L+
Sbjct: 606 SPLSPPPEESPLS-------PPPEASRLSPP--PEDSPMSPPPEESPMSP-PPEVSRLSP 655
Query: 507 L----RLSPVP------PVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNP 547
L RLSP P P P PT P PP P P P +P
Sbjct: 656 LPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP 706
Score = 50.4 bits (119), Expect = 4e-06
Identities = 57/155 (36%), Positives = 64/155 (41%), Gaps = 51/155 (32%)
Query: 425 AVGSPPPAATPT-----PTPPT--RKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNP 477
A+GSPPPAA PT PT P + + FL P A V PGP PG
Sbjct: 2112 ALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSV--------PGPDSPGELFLK- 2162
Query: 478 FLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPT---YISPLGGGPGLPP 534
LP PA PS +PF AP L P P APPT Y SP G P PP
Sbjct: 2163 -LPPQVPAQVPS-QDPFGLAPAYPLE---------PRFPTAPPTYPPYPSPT-GAPAQPP 2210
Query: 535 MM-----------------PPGPP--APNT-NPFL 549
M+ PPG P P+T +PFL
Sbjct: 2211 MLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFL 2245
Score = 43.5 bits (101), Expect = 5e-04
Identities = 39/130 (30%), Positives = 52/130 (40%), Gaps = 18/130 (13%)
Query: 422 LAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPG 481
L E+ SPPP +P +PP +P S L +S +S P +PP P P
Sbjct: 489 LEESPLSPPPEESPL-SPPPESSPFSPLE--------ESPLSPPEESPPSPALETPLSPP 539
Query: 482 --GGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPG-APPTYISPLGGGPGLPPMMPP 538
P + P +P P P +L SP P +PP SP+ P PM PP
Sbjct: 540 PEASPLSPPFEESPLSPPP------EELPTSPPPEASRLSPPPEESPMSPPPEESPMSPP 593
Query: 539 GPPAPNTNPF 548
+ PF
Sbjct: 594 PEASRLFPPF 603
Score = 43.1 bits (100), Expect = 7e-04
Identities = 77/277 (27%), Positives = 100/277 (36%), Gaps = 52/277 (18%)
Query: 252 GGPAPMAAAVPTAAPTSDPWGGPPVPPAA--DPWG-----GPAPT----------PASGD 294
G P+PM P A +P PPVP P G GP PT A+G+
Sbjct: 2529 GTPSPMRFTFPQAV--GEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGN 2586
Query: 295 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDP---WTPAPAFS 351
+P GPS G + + P+ P + DG +P AS +P
Sbjct: 2587 FHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRE 2646
Query: 352 DP---WGGSPAKPSTNGTTAGGF----DTEPDEFSDFDRLRTALPTSGSSAGELELLAGE 404
DP G S A GT G TE ++ RLR ELL +
Sbjct: 2647 DPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLR-------------ELLIRQ 2693
Query: 405 VPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSR 464
R+ + + A AVG PP + P+ P + P A D SLV
Sbjct: 2694 QIQRNTLRQEKE-TAAAAAGAVG-PPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGL 2751
Query: 465 PGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT 501
P +K S P L GP + PS +P PPAT
Sbjct: 2752 -----PPSKLSGPIL---GPGSFPSDDRLSRPPPPAT 2780
Score = 41.6 bits (96), Expect = 0.002
Identities = 88/335 (26%), Positives = 116/335 (34%), Gaps = 45/335 (13%)
Query: 242 PAPAPTTDPW-GGPA------PMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGD 294
P P+ P G PA P + +P P S P G P + P P P P P
Sbjct: 885 PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS-PSGEPSLSPQLMP---PDPLPPPLS 940
Query: 295 PWRPAAPAGPSVDPWGGTPAP--AAGEGPTPDPWGSSDGGVPVSGP---SASDPWTPAPA 349
P AA A P++ P G P A G+ P + P+S P + +DP P
Sbjct: 941 PIITAA-APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM 999
Query: 350 FSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
P GSP P A EP L+ +L S + A + S
Sbjct: 1000 ILPPSPGSPVGP------ASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPS 1053
Query: 410 P--------GAFDMSGVRGSLAEAVGSPP-PAATPTPTPPTRKTPESFLG-----PNAAL 455
P G D + + E V P PA P+ T P +P L P AL
Sbjct: 1054 PLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPL-PSPMGDLSCPAPSPAPAL 1112
Query: 456 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPV 515
D L P G A PG P G + + + + L+ L+PV P+
Sbjct: 1113 DDFSGLGEDTAPLD-GIDA-----PGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPM 1166
Query: 516 PGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 550
P + G P P P AP T P L+
Sbjct: 1167 EVYPECKQTAGQGSPCEEQEEPRAPVAP-TPPTLI 1200
Score = 38.1 bits (87), Expect = 0.021
Identities = 87/349 (24%), Positives = 114/349 (32%), Gaps = 56/349 (16%)
Query: 243 APAPTTDPWGGP--APMAAAVPTAAPTSDPWGGPPV-PPAADPWGGPAPTPASGDPWRPA 299
+P P P P A + P +P S P P+ PP P P + P
Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668
Query: 300 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPA---FSDPWGG 356
+P P + +P P A +P P S P S P P +P P S P
Sbjct: 669 SPLSPPPEESPTSPPPEASR-LSPPPEDS-----PTSPPPEDSPASPPPEDSLMSLPLEE 722
Query: 357 SPAKPSTNGTT----AGGFDTEPDEFSDFDRLRTALPTSGSSAGELEL----------LA 402
SP P + G P R P A E L
Sbjct: 723 SPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782
Query: 403 GEVPARSPGAFD--MSGVRGSLAEAVGSPPPAATPTPTPP-----------TRKTPESFL 449
E P SP A +S L + + P +P P P + ++ E L
Sbjct: 783 PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCL 842
Query: 450 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL 509
P L + +P +P K P PG PA P PP +L+ L
Sbjct: 843 SPRPEESHLSPELEKPPLSPRPEKP--PEEPGQCPAPEELPLFP----PPGEPSLSPLLG 896
Query: 510 SPVPPVPGAPPTYISPL--------GGGPGLPP-MMPPGPPAPNTNPFL 549
P PG PP +SPL G P L P +MPP P P +P +
Sbjct: 897 EPALSEPGEPP--LSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPII 943
Score = 36.6 bits (83), Expect = 0.061
Identities = 46/189 (24%), Positives = 70/189 (37%), Gaps = 37/189 (19%)
Query: 168 GPPPEAEQAWP-----QSSGEEELQLQLALA-------MSKEEADQEERIRRGDDLRLQM 215
GP ++ Q P + G+ QLQ LA +S ++ Q + + L+
Sbjct: 4176 GPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQ 4235
Query: 216 AIEESKR-ETGGKEESSLMDLADV------FTAPAPAPTTDPWGGPAPMAAA---VPTAA 265
A+ ++ + G + S L L F P P + GP P P A
Sbjct: 4236 AVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGA 4295
Query: 266 PTSDPWGGP--PVPPAADPW-----------GGPAPTPASGDPWRPAAPA--GPSVDPWG 310
++ P GP P PP + P PT A P P P GP+++P
Sbjct: 4296 LSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPP 4355
Query: 311 GTPAPAAGE 319
G +PAA +
Sbjct: 4356 GRVSPAAAQ 4364
Score = 36.6 bits (83), Expect = 0.061
Identities = 42/134 (31%), Positives = 56/134 (41%), Gaps = 20/134 (14%)
Query: 423 AEAVGSPPPAATP-TPTPPTRKT----PE--SFLGPNAALVDLDSLVSRPG-----PTPP 470
++AV PP P T T P + P+ F GP + RP P PP
Sbjct: 4234 SQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPP 4293
Query: 471 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYI-SPLGGG 529
GA ++ P L P PS +P +P P+ L S +P PPT+ +P G
Sbjct: 4294 GALSTGPVLGPVHPTPPPS--SPQEPKRPSQLPSPS---SQLPTEAQLPPTHPGTPKPQG 4348
Query: 530 PGLPPMMPPGPPAP 543
P L P PPG +P
Sbjct: 4349 PTLEP--PPGRVSP 4360
Score = 36.2 bits (82), Expect = 0.080
Identities = 70/278 (25%), Positives = 85/278 (30%), Gaps = 83/278 (29%)
Query: 270 PWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAA-GE---GPTPDP 325
P P P +P PAP P P PS+ P G PA + GE P P+
Sbjct: 859 PLSPRPEKPPEEPGQCPAPEELPLFP----PPGEPSLSPLLGEPALSEPGEPPLSPLPEE 914
Query: 326 WGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLR 385
S G P P P P P P P +
Sbjct: 915 LPLSPSGEPSLSPQLMPP-DPLPP--------PLSPI---------------------IT 944
Query: 386 TALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTP 445
A P + S GELE G P S + + E SPPP A T
Sbjct: 945 AAAPPALSPLGELEYPFGAKGDSDPE----SPLAAPILETPISPPPEANCTD-------- 992
Query: 446 ESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLN 505
P P PP +P G GP+ +P PP L
Sbjct: 993 -------------------PEPVPPMILPPSP-----GSPVGPASPILMEPLPPQCSPLL 1028
Query: 506 QLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 543
Q L P +PP+ SP P L P+ P P +P
Sbjct: 1029 QHSLVP----QNSPPSQCSP----PAL-PLSVPSPLSP 1057
Score = 35.4 bits (80), Expect = 0.14
Identities = 81/305 (26%), Positives = 102/305 (33%), Gaps = 59/305 (19%)
Query: 235 LADVFTAPAPAPTTD------PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAP 288
L+ + TA AP + P+G P AAP + P PP P P
Sbjct: 939 LSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILET---PISPPPEANCTDPEP 995
Query: 289 TPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP 348
P P P +P GP+ P P P P P S PS P PA
Sbjct: 996 VPPMILPPSPGSPVGPA-SPILMEPLP-----PQCSPLLQHSLVPQNSPPSQCSP--PAL 1047
Query: 349 AFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 408
S P SP P G G D E + + + + P E PA
Sbjct: 1048 PLSVP---SPLSPI--GKVVGVSDEA--ELHEMETEKVSEP--------------ECPAL 1086
Query: 409 SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVD-LDSLVSRPGP 467
P A L +G + P P+P S LG + A +D +D+ S+P P
Sbjct: 1087 EPSA------TSPLPSPMGD---LSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEP 1137
Query: 468 -TPPGAKASNPFLPGGGPATGPSVTNPFQPA---PPATLTLNQ-----LRLSPVPPVPGA 518
PG+ AS L G P P P P T Q + P PV
Sbjct: 1138 GQTPGSLASE--LKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPT 1195
Query: 519 PPTYI 523
PPT I
Sbjct: 1196 PPTLI 1200
Score = 34.7 bits (78), Expect = 0.23
Identities = 98/432 (22%), Positives = 131/432 (30%), Gaps = 72/432 (16%)
Query: 169 PPPEAEQAWPQ------SSGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKR 222
PPPEA + +P S EE L S+ E D + EES
Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPE-------DSPMSPPPEESPM 644
Query: 223 ETGGKEESSLMDLADVFTAPAPAPTTDPWGGP---APMAAAVPTAAPTSDPWGGPPVPPA 279
E S + V + +P P P P +P + + + P P PP
Sbjct: 645 SP--PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP 702
Query: 280 ADPWGGPAPT------PASGDPWRPAAPAGPSVDPWGGTP--APAAGE---GPTPD-PWG 327
D P P P P P P P + P P +P E P P+ P
Sbjct: 703 EDSPASPPPEDSLMSLPLEESPLLPL-PEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL 761
Query: 328 SSDGGVPVSGPSASDPWTPA----PAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDR 383
S P P +P A P S G P TE S
Sbjct: 762 SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSP-QTEEPHLSPVPE 820
Query: 384 LRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRK 443
P S + E P SP + S + L + SP P P
Sbjct: 821 EPCLSPQPEESHLSPQ---SEEPCLSPRP-EESHLSPELEKPPLSPRPEKPPEEPGQCPA 876
Query: 444 TPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPF------LPGGGPATGPSVT--NPFQ 495
E L P L L+ P + PG +P P G P+ P + +P
Sbjct: 877 PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936
Query: 496 P---------APPATLTLNQLRL---------------SPVPPVPGAPPTYISPLGGGPG 531
P APPA L +L +P+ P +PP + P
Sbjct: 937 PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV 996
Query: 532 LPPMMPPGPPAP 543
P ++PP P +P
Sbjct: 997 PPMILPPSPGSP 1008
Score = 33.1 bits (74), Expect = 0.68
Identities = 69/272 (25%), Positives = 94/272 (34%), Gaps = 71/272 (26%)
Query: 312 TPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSD------PWGGSPAKPSTNG 365
T A AAG P WG+ PS+ PAF P+ G+ K S G
Sbjct: 2706 TAAAAAGAVGPPGSWGAE--------PSS-------PAFEQLSRGQTPFAGTQDKSSLVG 2750
Query: 366 ---TTAGGFDTEPDEFSDFDRLRTALPTSGSSAGEL---ELLAGEVP----ARSPGAFDM 415
+ G P F DRL P + S+ ++ +L+ G A PG+ +
Sbjct: 2751 LPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPL 2810
Query: 416 SGVRGSL-----AEAVGSPPPAATPT-PTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
+ L A A S A + P+ P + LG + L + + + PG
Sbjct: 2811 QQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALG--SPLAGISTRLPGPGEPV 2868
Query: 470 PGAKASNPFL-----------PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGA 518
PG F+ PGG P G PP + R PV
Sbjct: 2869 PGPAGPAQFIELRHNVQKGLGPGGTPFPGQG--------PP-----QRPRFYPV----SE 2911
Query: 519 PPTYISPLG----GGPGLPPMMPPGPPAPNTN 546
P ++P G GLPP P PPAP N
Sbjct: 2912 DPHRLAPEGLRGLAVSGLPPQKPSAPPAPELN 2943
Score = 30.4 bits (67), Expect = 4.4
Identities = 96/438 (21%), Positives = 149/438 (34%), Gaps = 100/438 (22%)
Query: 192 LAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADV-----FTAPAPAP 246
L S+++ +E+ +R + L Q+ K+E SL+ L + F+ AP
Sbjct: 4532 LVSSRKKLRKEDGVRASEALLKQL-----------KQELSLLPLTEPAITANFSLFAPFG 4580
Query: 247 TTDPWGGPAPM-----AAAVPTAAP------TSDPWGGPPVPPAADP-----------WG 284
+ P G + + + A+PT T + PP PP++ P
Sbjct: 4581 SGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVN 4640
Query: 285 GPAPTPASGDPWRPAAPAGPS------------VDPWGGTPAPAAGEGPTPDPWGSSDGG 332
G P+ G+ + AA A S +D P P + D
Sbjct: 4641 GVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSD 4700
Query: 333 VPVSGPSASDPWT----PAPAFSDPWGG---------SPAKPSTNGTTAGGF-DTEPDEF 378
P S AS P + AP F G SP P + F DT+P
Sbjct: 4701 SPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGA 4760
Query: 379 SDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPT-- 436
+ + LP + G+ ++ + + A +++GV ++AE + P +
Sbjct: 4761 LGLE-VPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLF 4819
Query: 437 PTPPTRKTPE----SFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTN 492
P P R E GP L+ P P K + LPG + + +
Sbjct: 4820 PESPARAGTEPKKGEAEGPGGKEKGLEG--KSPDTGPDWLKQFDAVLPGYTLKSQLDILS 4877
Query: 493 PFQ-----PAPP---------ATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMP- 537
+ P PP + L + QL +P P P PP SPL P PP P
Sbjct: 4878 LLKQESPAPEPPTQHSYTYNVSNLDVRQLS-APPPEEPSPPP---SPLAPSPASPPTEPL 4933
Query: 538 --------PGPPAPNTNP 547
PP P+ P
Sbjct: 4934 VELPTEPLAEPPVPSPLP 4951
Score = 30.0 bits (66), Expect = 5.7
Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 237 DVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW 296
DV AP P +P P+P+A + P + PT P P A P P P +S +
Sbjct: 4902 DVRQLSAPPPE-EPSPPPSPLAPS-PASPPTEPLVELPTEPLAEPPVPSPLPLASSPESA 4959
Query: 297 RPAAPAGP 304
RP A P
Sbjct: 4960 RPKPRARP 4967
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 76.3 bits (186), Expect = 7e-14
Identities = 87/360 (24%), Positives = 124/360 (34%), Gaps = 58/360 (16%)
Query: 240 TAPAPAPTTDPWGGPA------PMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASG 293
++P P P + P P P+++++P + PT+ P P P P P ASG
Sbjct: 1412 SSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLP--APASAPLTIPISAPLTVSASG 1469
Query: 294 D-----------PWRPAAPAGPSVDPWGGTPAPAA---GEGPTPDPWGSSDGGVPVS--- 336
P PAAP PS+ P G +P+ +A G P S G P+
Sbjct: 1470 PALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAP 1529
Query: 337 ------------GPSASDPWTPAPAFSDPWGGSP----AKPSTNGTTAGGFDTEPDEFSD 380
P+ S PA A + P+ +P A+ S + +
Sbjct: 1530 TSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAP 1589
Query: 381 FDRLRTA------------LPTSGSSAGELELLAGE---VPARSPGAFDMSGVRGSLAEA 425
+TA LP S G +LA VP +P + G + A
Sbjct: 1590 MAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSS--TPGTSLASASP 1647
Query: 426 VGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPA 485
V +P P P+ T P P+ A +L PT G+ S G G
Sbjct: 1648 VPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNP 1707
Query: 486 TGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 545
GP T P ++L + + P P PT L P L P P GP +T
Sbjct: 1708 QGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHT 1767
Score = 62.4 bits (150), Expect = 1e-09
Identities = 85/343 (24%), Positives = 120/343 (34%), Gaps = 52/343 (15%)
Query: 235 LADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGD 294
L V P P P P P+ +P + S GPP+ PA+ P P P
Sbjct: 1019 LGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRP-----PGPVLLP 1073
Query: 295 PWRPAAPAGPSVDP-----WGGT---PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTP 346
P +P + + P V P GT P P PTP P S P T
Sbjct: 1074 PLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTV 1133
Query: 347 APAFSDPWGGSPAKPSTNGTTAGGFDT--------EPDEFSDFDRLRTALPTSG-SSAGE 397
P ++ P PA +T TT T P ++ LP+ S G+
Sbjct: 1134 PPGYTFP----PAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQ 1189
Query: 398 LELLAGEVPARSPGA----FDMSGVRGSLAE------AVGSPPPAATPTPTPPTRKTPES 447
L LA A + G+ F + G + +L AVG P P +
Sbjct: 1190 LASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHH 1249
Query: 448 FLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAP----PATLT 503
+ A + + ++ PGPTP LP P+T P+ T P P T+
Sbjct: 1250 LISQPAHVALIQAVAPTPGPTPVSV------LPSSTPSTTPAPTGLSLPLAANQVPPTMV 1303
Query: 504 LNQ------LRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGP 540
N +R +P + PP +P GLP ++ P P
Sbjct: 1304 NNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRP 1346
Score = 51.6 bits (122), Expect = 2e-06
Identities = 81/306 (26%), Positives = 107/306 (34%), Gaps = 60/306 (19%)
Query: 253 GPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGT 312
G AP+ + P P+S P GP P P P +P S P + + P P T
Sbjct: 1391 GAAPLTISSPLHVPSSLP--GPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVP---T 1445
Query: 313 PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTP-----APAFSDPWGGSP--AKPSTNG 365
PA P P S+ V SGP+ TP PA P +P A PS +
Sbjct: 1446 TLPAPASAPLTIPI-SAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASA 1504
Query: 366 TTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEA 425
T G L TA S S LL + PG + ++A
Sbjct: 1505 LTLG--------------LATAPSLSSSQTPGHPLLLAPTSSHVPG------LNSTVA-- 1542
Query: 426 VGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKA-SNPFLPGGGP 484
PA +P P + PN A L P ++A + P P P
Sbjct: 1543 -----PACSPVLVPASALASPFPSAPNPAPAQASLLA----PASSASQALATPLAPMAAP 1593
Query: 485 ATGPSVTNPFQPAPPATLTLNQLRLSPVP---PVPGAPPTYISPLGGGPGLPPMMPPGPP 541
T ++ P PAPP L+P+P P PGA P S P + P PG
Sbjct: 1594 QT--AILAP-SPAPP---------LAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTS 1641
Query: 542 APNTNP 547
+ +P
Sbjct: 1642 LASASP 1647
Score = 45.8 bits (107), Expect = 1e-04
Identities = 71/257 (27%), Positives = 100/257 (38%), Gaps = 35/257 (13%)
Query: 286 PAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGV--------PVSG 337
P PTP S P++ + P G + AA + P P ++ GV P G
Sbjct: 1267 PGPTPVSV---LPSSTPSTTPAPTGLSLPLAANQVP---PTMVNNTGVVKIVVRQAPRDG 1320
Query: 338 PSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGE 397
+ P PAP P G PA + T G P R +PT
Sbjct: 1321 LTPVPPLAPAPR--PPSSGLPAVLNPRPTLTPGRLPTPT----LGTARAPMPTPTLVRPL 1374
Query: 398 LELL---AGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 454
L+L+ + EV A +PGA ++ + L P PA++P P P +P + +
Sbjct: 1375 LKLVHSPSPEVSASAPGAAPLT-ISSPLHVPSSLPGPASSPMPIP--NSSPLASPVSSTV 1431
Query: 455 LVDLDSLVSRPGPTPPGAKASNPF-LPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVP 513
V L S + PT A AS P +P P T + PA LT L+PV
Sbjct: 1432 SVPLSSSLPISVPTTLPAPASAPLTIPISAPLT-------VSASGPALLTSVTPPLAPVV 1484
Query: 514 PVPGAPPTYISPLGGGP 530
P PP+ ++P G P
Sbjct: 1485 PAAPGPPS-LAPSGASP 1500
Score = 44.3 bits (103), Expect = 3e-04
Identities = 71/273 (26%), Positives = 98/273 (35%), Gaps = 43/273 (15%)
Query: 235 LADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADP-WGGPAPTP--- 290
LA PAP P P + A VP+ P+ + PA P GG +P+
Sbjct: 1642 LASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLS 1701
Query: 291 -ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP- 348
+G+P P S+ PA+ PTP S G P+ GP+ + PAP
Sbjct: 1702 LGTGNPQGPFPTQTLSL-------TPASSLVPTPAQTLSLAPGPPL-GPTQTLSLAPAPP 1753
Query: 349 -AFSDPWGGSPAKPSTNGTTAGGFD-TEPDEFSDFDRLRTALPTSGSSAGELELLAGEVP 406
A + P G +PA T + P +PT G +A + LA
Sbjct: 1754 LAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALA-PAS 1812
Query: 407 ARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPG 466
+SP S A ++ A P P + P S P D+L R G
Sbjct: 1813 TQSP---------ASQASSLVVSASGAAPLPVTMVSRLPVSKDEP-------DTLTLRSG 1856
Query: 467 PTPPGAKASNPFLPGGGPATGPSVTNPFQPAPP 499
P P + A++ GGP QP PP
Sbjct: 1857 PPSPPSTATS----FGGPRPRR------QPPPP 1879
Score = 38.1 bits (87), Expect = 0.021
Identities = 42/140 (30%), Positives = 55/140 (39%), Gaps = 21/140 (15%)
Query: 410 PGAFDMSGVRGSLAEAVGS---PPPAA--TPTPTPPTRKTPESFLGPNAALVDLDSLVSR 464
PG +RG+ AE G+ P +A T + T P R +P P A R
Sbjct: 2391 PGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPA--------PR 2442
Query: 465 PGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYIS 524
P PTP A A+ P L V+ P + P +T+ + + P PP P P S
Sbjct: 2443 PRPTPASAPAAIPAL------VPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSS 2496
Query: 525 PLGGGPG--LPPMMPPGPPA 542
P P PP PPA
Sbjct: 2497 PACTPPPACTPPPAHTPPPA 2516
Score = 36.2 bits (82), Expect = 0.080
Identities = 80/319 (25%), Positives = 102/319 (31%), Gaps = 41/319 (12%)
Query: 242 PAPAPTTDPWGGPAPMAAAVPTAAPTS------DPWGGPPVPPAADPWGGPAPTPASGDP 295
PA AP P P P++A VP +AP PP P P PA TP
Sbjct: 2447 PASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACT 2506
Query: 296 WRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS-GPSASDPWTPAPAFSDPW 354
P A P TP+ GP P +S +P+ P A A A + P
Sbjct: 2507 -PPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAE---LCAQALASPE 2562
Query: 355 GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGS------SAGELELLAGEVPAR 408
A +++ T++ D + LP S SA L L AG +P
Sbjct: 2563 SLELASVASSETSSLSLVPPKDLLPVAVEI---LPVSEKNLSLTPSAPSLTLEAGSIP-- 2617
Query: 409 SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT 468
G EA S T T P + P N + + P
Sbjct: 2618 ----------NGQEQEAPDS-AEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQE 2666
Query: 469 PPGA-KASNPFLPGGGPATGPSVTNPFQPAP-PATLTLNQLRLSPVPPVPGAPP-----T 521
P A + S P + P A A T + SP P P PP
Sbjct: 2667 PLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSA 2726
Query: 522 YISPLGGGPGLPPMMPPGP 540
+ G G G P PPGP
Sbjct: 2727 DVEIRGQGTGRPG-QPPGP 2744
Score = 35.8 bits (81), Expect = 0.10
Identities = 41/146 (28%), Positives = 55/146 (37%), Gaps = 24/146 (16%)
Query: 419 RGSLAEAVGSPPPAATPTPT---------PPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
R L E +P P P P P ++ + + N L + RP P
Sbjct: 971 RRVLLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRP---P 1027
Query: 470 PGAKASNPFLPGGGPATGP-----SVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYI- 523
PG + S PG P P S + P PA+ + L P+ P G+ P +
Sbjct: 1028 PGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLP 1087
Query: 524 SPLG--GGPGLPPM----MPPGPPAP 543
SPLG G PP + P PPAP
Sbjct: 1088 SPLGVLSGTSRPPTPTLSLKPTPPAP 1113
Score = 32.0 bits (71), Expect = 1.5
Identities = 38/137 (27%), Positives = 51/137 (37%), Gaps = 21/137 (15%)
Query: 220 SKRETGGKEESSLMDLADVFTA-PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPP 278
S+R G + E+ + V +A + TT P PA P P P P P
Sbjct: 2396 SERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIP 2455
Query: 279 AADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGP 338
A P AP P S AP ++ P P+P P+ P P S P
Sbjct: 2456 ALVPVPVSAPVPIS-------APNPITILPVHILPSPPP---PSQIP--------PCSSP 2497
Query: 339 SASDP--WTPAPAFSDP 353
+ + P TP PA + P
Sbjct: 2498 ACTPPPACTPPPAHTPP 2514
Score = 32.0 bits (71), Expect = 1.5
Identities = 77/300 (25%), Positives = 92/300 (30%), Gaps = 57/300 (19%)
Query: 260 AVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGE 319
A T P P P+ GP +P G P AAP+ TP
Sbjct: 2773 AASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCE-AAPSSSL-----PTPPQQPFI 2826
Query: 320 GPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFS 379
G + GG P +G A TP PA G P K + G D P
Sbjct: 2827 ARRHIELGVTGGGSPENGDGALLAITP-PAVKRRRGRPPKKNRSPADAGRGVDEAPS--- 2882
Query: 380 DFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSP--PPAATPTP 437
L G+ P V G V P P P P
Sbjct: 2883 -------------------STLKGKTNGADP-------VPGPETLIVADPVLEPQLIPGP 2916
Query: 438 TPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPG----GGPATGPSVTNP 493
P P+ PN L ++ R G P KA + +PG G S T P
Sbjct: 2917 QP---LGPQPVHRPNPLLSPVEK--RRRGRPP---KARDLPIPGTISSAGDGNSESRTQP 2968
Query: 494 FQPAPPATLT-LNQLRLSPVPPVPGAPPTY---ISPLGGGPGLPPMMPPGPPAPNTNPFL 549
P P+ LT L L + P V T SP G PP PP P P+ P L
Sbjct: 2969 --PPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPS-PRPSQLPVL 3025
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 74.7 bits (182), Expect = 2e-13
Identities = 86/292 (29%), Positives = 98/292 (33%), Gaps = 59/292 (20%)
Query: 252 GGPAPMAAAVPTAAPTSDPWGGPPVPPA--ADPWGGPAPTPASGDPWRPAAPAGPSVDPW 309
G PA A A P A P P PPA A P GG P P RP PAGP+
Sbjct: 65 GSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPA---- 120
Query: 310 GGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAG 369
PAA P P+ S VP + A+ P PAPA PAKP+ A
Sbjct: 121 ----PPAAKLRPPPEGSAGSCAPVPAAAAVAAGP-EPAPA-------GPAKPAGPAALAA 168
Query: 370 GFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSP 429
P P G G G PGA +L + +
Sbjct: 169 RAGPGPG------------PGPGPGPG-----PGPGKPAGPGAAQTLNGSAALLNSHHAA 211
Query: 430 PPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPS 489
PA + P AAL+ L P P PG P P G A P+
Sbjct: 212 APAVSLVNNGP------------AALLPL------PKPAAPGTVIQTP--PFVGAAAPPA 251
Query: 490 VTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPP 541
P PA PA + PP P AP T P G G P P PP
Sbjct: 252 PAAPSPPAAPAPAA----PAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPP 299
Score = 59.3 bits (142), Expect = 9e-09
Identities = 86/326 (26%), Positives = 111/326 (34%), Gaps = 57/326 (17%)
Query: 242 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGP-PVPPAADPWGGPAPTPASG-----DP 295
PAPA P GPA +AA A P P GP P P P G A +G +
Sbjct: 152 PAPAGPAKP-AGPAALAAR---AGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNS 207
Query: 296 WRPAAPA------GPS----------------VDPWGGTPAPAAGEGPTPDPWGSSDGGV 333
AAPA GP+ P+ G AP A P+P
Sbjct: 208 HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPA-----APA 262
Query: 334 PVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGS 393
P + +A P PAPA G PA P T P + A P
Sbjct: 263 PAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPA-----VPPPAAAQNGGSAGAAPAPAP 317
Query: 394 SAGELELLAGEVPARSPGAFDMSGVRGSLAEAV--GSPPPAATPTPTPPTRKTPESFLGP 451
+AG ++G+ + A GV+ + V +PP A T + P +GP
Sbjct: 318 AAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGP 377
Query: 452 NAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT-----LTLNQ 506
+ + P PP A + LP G +VT P AT TL
Sbjct: 378 T-----MQGALPSPAAVPPPAPGTPTGLPKGAAG---AVTQSLSRTPTATTSGIRATLTP 429
Query: 507 LRLSPVPPVPGAPPTYISPLGGGPGL 532
L+P P P PT I PG+
Sbjct: 430 TVLAPRLPQPPQNPTNIQNFQLPPGM 455
Score = 55.8 bits (133), Expect = 1e-07
Identities = 91/343 (26%), Positives = 120/343 (34%), Gaps = 60/343 (17%)
Query: 241 APAPAPTTDPWGG----PAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW 296
AP T P+ G PAP A + P A + P PP PP PAP + P
Sbjct: 233 APGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP-------PAPATLARPPG 285
Query: 297 RPAAP--AGPSVDPWGGTPAPA-----AGEGPTPDPWGSSDGGV---PVSGPSASDPWTP 346
PA P A P+V P PA A AG P P P GV P G +A+ P
Sbjct: 286 HPAGPPTAAPAVPP----PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPG 341
Query: 347 APAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPT--------SGSSAGEL 398
A S A P+ A G + ++ ALP+ G+ G
Sbjct: 342 VKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLP 401
Query: 399 ELLAGEVP---ARSPGAFDMSGVRGSLAEAVGS---PPPAATPT-----PTPPTRKTPES 447
+ AG V +R+P A SG+R +L V + P P PT PP S
Sbjct: 402 KGAAGAVTQSLSRTPTA-TTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRS 460
Query: 448 FLG-----PNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATL 502
G P AL + ++ P A P P P S AP +
Sbjct: 461 ENGQLLMIPQQALAQMQ---AQAHAQPQTTMAPRPATPTSAPPVQISTVQ----APGTPI 513
Query: 503 TLNQLRLSPVPPVPGAPPTYISP---LGGGPGLPPMMPPGPPA 542
Q+ + + T + P L PG+ P + G A
Sbjct: 514 IARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAA 556
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 72.8 bits (177), Expect = 8e-13
Identities = 92/311 (29%), Positives = 119/311 (38%), Gaps = 50/311 (16%)
Query: 254 PAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPT--PASGDPWRPAAPAGP------S 305
P+P A P+A + +A P PA + A G P PA P+ P +
Sbjct: 211 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 270
Query: 306 VDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTP-APAFSDPWGGSPAKPSTN 364
+ P TP P P P SS P++ PS S P +P AP PA P +
Sbjct: 271 LRPPQVTP-PRKDAAPALGPLSSS----PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325
Query: 365 GTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAE 424
TT+ G T + LP+ L LA P P +L
Sbjct: 326 ATTSLGSPT-------LQATHSFLPSP-----PLSPLATPPPQAPPAL--------ALPP 365
Query: 425 AVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGP 484
P P A+P +P +P++ PNA V L P P+PP PF P P
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQA---PNALAVHLLQAPFSPPPSPP---VQAPFSPPASP 419
Query: 485 ATGPSVTNPFQPAPPATLTLNQLRLSPVPPV-PGAPPTYISPLGGGPGL--PPMM----- 536
PS T P Q APP +L L++ P PP P P+ P P L PP+
Sbjct: 420 PVSPSATPPSQ-APP-SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477
Query: 537 PPGPPAPNTNP 547
P PPA T P
Sbjct: 478 PQAPPALATPP 488
Score = 65.5 bits (158), Expect = 1e-10
Identities = 93/319 (29%), Positives = 115/319 (36%), Gaps = 46/319 (14%)
Query: 254 PAPMAAAVPTAAPTSDPWGGPPVPPAADPWGG--------PAPTPASGDPWRPAAPAGPS 305
PA A + T P P PPV PAA G P A G + P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 306 VDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPS-ASDPWTPAPAFSDPWGGSPAKPSTN 364
P + PA+G G P ++ G PVS P AS P P G + S
Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPL-----GQKGLRISAE 130
Query: 365 GTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR-SPGAFDMSGVRGSLA 423
T A G TE + R+AL SAG +G P SP S G+
Sbjct: 131 ETVARGKATEAPK-------RSAL-----SAGARRDTSGPTPGTPSPAMARRSRAAGT-- 176
Query: 424 EAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT-------PPGAKASN 476
VG P PA + P PPT +S + S +R P+ P S+
Sbjct: 177 -EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 235
Query: 477 PFLPGGGPA-TGPSVTN----PFQPAPPATLTLNQLRLSPV-PPVPGAPPTYISPLGGGP 530
P PA +GPS P P+ P L LR V PP A P + PL P
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA-LGPLSSSP 294
Query: 531 GLPPMMPPGPPAPNTNPFL 549
P P PP+P+ P L
Sbjct: 295 LATP-SPSAPPSPSAPPSL 312
Score = 63.9 bits (154), Expect = 4e-10
Identities = 96/336 (28%), Positives = 116/336 (34%), Gaps = 77/336 (22%)
Query: 241 APAPAP-TTDPWGGPAPMAAAVPTAAPTSDPWGGPP-VPPAADPWGGPAPTPASGDPWRP 298
APA P ++ P P+P A P+A P+ PP PP+ +PT + + P
Sbjct: 284 APALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343
Query: 299 AAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSP 358
+ P P P P PA P P P AS P +P
Sbjct: 344 SPPLSPLATPPPQAP-PALALPPLQAP----------PSPPASPPLSPL----------- 381
Query: 359 AKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGV 418
A PS A FS P S ++ P SP A S
Sbjct: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS----------PPVSPSATPPSQA 431
Query: 419 RGSLA----EAVGSPP------PAATPTP-TPPTRKTPESFLG-------PNAALVDLDS 460
SLA + SPP P+ATP P PP P L P A L +
Sbjct: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 491
Query: 461 LVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQ-------------PAPPATLTLNQL 507
L S P P A PF P P T P Q P+PPA+ TL
Sbjct: 492 LPSPPASFPGQA----PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 547
Query: 508 RLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 543
R PP PG P T +S GP L + PGPP P
Sbjct: 548 RR---PPTPG-PDTSVS----GPRLTLALAPGPPPP 575
Score = 60.1 bits (144), Expect = 5e-09
Identities = 80/312 (25%), Positives = 103/312 (33%), Gaps = 44/312 (14%)
Query: 241 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA- 299
+P +P P P+P A P+ PP PP P+ PA P S P+
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430
Query: 300 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPS---ASDPWTPAPAFSDPWGG 356
AP + P P+P A +P P++ P A P PA + P
Sbjct: 431 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP--P 488
Query: 357 SPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA---- 412
A PS + G P L T P + L P SP
Sbjct: 489 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548
Query: 413 --------FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSR 464
+SG R +LA A G PP PP+R + GP DL S
Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPP--------PPSRSPSSTLSGP-----DLAGHSSS 595
Query: 465 PGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPV-----PGAP 519
TP + + P GG A P PA + P PP+ PGAP
Sbjct: 596 ATSTPEELRGYDSG-PEGGAAASPPPDAELAACHPAAWS-----RGPAPPLAFRGAPGAP 649
Query: 520 PTYISPLGGGPG 531
+ P GPG
Sbjct: 650 LPW--PPATGPG 659
Score = 38.1 bits (87), Expect = 0.021
Identities = 39/141 (27%), Positives = 49/141 (34%), Gaps = 19/141 (13%)
Query: 241 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAAD--PWGGPAPTPASGDPWRP 298
A AP P P P+ + A +S P D P GG A +P
Sbjct: 567 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 626
Query: 299 AAPAGPSVDPWGGTPAPAA---GEGPTPDPW------GSSDGGVPVSGPSASDPWTPAPA 349
PA W PAP G P PW GS+DG + + TPAP
Sbjct: 627 CHPAA-----WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681
Query: 350 FSDPWGGSPAKPSTNGTTAGG 370
DP P+ ++ G A G
Sbjct: 682 ALDP---GPSPGTSGGKAAAG 699
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 72.0 bits (175), Expect = 1e-12
Identities = 88/318 (27%), Positives = 114/318 (35%), Gaps = 52/318 (16%)
Query: 255 APMAAAVPTAAPTS-DPWGGPPVPPAADP----WGG-------PAPTPASGDPWRPAAPA 302
AP +P A P + + G PP PP D GG P P + G P ++PA
Sbjct: 431 APAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPA 490
Query: 303 GPSV--DPWGGTPAPAAGEGPTP-----DPWGSSD---GGVPVSGPSAS-DPWTPAPAFS 351
GP D E T +P ++ G P+S S+ P P S
Sbjct: 491 GPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNS 550
Query: 352 DPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPG 411
P P PS+ ++ G D P D D EL+L G P PG
Sbjct: 551 QPGFRGPTPPSSRPSSTGLEDISPTPLPDSD-----------EDEELDLGLGPRPPPEPG 599
Query: 412 AFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPG 471
D +G+ AE + TPT + G + + D D + S P
Sbjct: 600 PPDPAGLLSQTAEV--ALDLVGDRTPTSEKMDEGQQSSGEDMEISD-DEMPSAP---ITS 653
Query: 472 AKASNPFL--PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGG 529
A P + PG PSV P P PP P+PP P PP P G
Sbjct: 654 ADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPP------GFPPLPPPPPPPP----PQPGF 703
Query: 530 PGLPPMMPPGPPAPNTNP 547
P PP+ PP PP P +P
Sbjct: 704 PMPPPLPPPPPPPPPAHP 721
Score = 65.9 bits (159), Expect = 9e-11
Identities = 109/452 (24%), Positives = 152/452 (33%), Gaps = 68/452 (15%)
Query: 136 DEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMS 195
+E+ + E + +E +A+ + AS+ E P + + L ++ + +
Sbjct: 1135 EEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIE 1194
Query: 196 KEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPA-------PTT 248
E EER D+ L + +EE EE L + +P P P
Sbjct: 1195 TEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPL 1254
Query: 249 DPWGGPA---------PMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 299
P P PM +P P P PP PP+ P P P + D P+
Sbjct: 1255 SPERAPEHDLEVEPEPPMMLPLPLQPPLPPP--RPPRPPS------PPPEPETTDASHPS 1306
Query: 300 APAGPSVD---PWGGTPAPAAGEGPTPDPWGSSDGGVPV-----SGPSASDPWTPAPAFS 351
P P + P + + + + ++ GG P SG S S P P FS
Sbjct: 1307 VPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFS 1366
Query: 352 DPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPG 411
P PS + ++GG P F PT +G L L +P G
Sbjct: 1367 YP------APSPS-LSSGGLPRTPGRDFSFT------PTFSEPSGPLLLPVCPLPT---G 1410
Query: 412 AFDMSGVRGSLAEAV----GSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGP 467
D G LA V G P P P P P P A L L+ P
Sbjct: 1411 RRDERS--GPLASPVLLETGLPLPLPLPLPLPLA--LPAVLRAQARAPTPLPPLLPAPLA 1466
Query: 468 TPPGAKASNPFLPGGGPATGPSVTNPF-QPAPPATLTLNQLRLSPVPPVPGAPPTY---- 522
+ P P P P + S+ P +P A L L L P P P T+
Sbjct: 1467 SCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRT 1526
Query: 523 --ISPLGGG-----PGLPPMMPPGPPAPNTNP 547
+ G P LPP PP PP P P
Sbjct: 1527 VTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEP 1558
Score = 59.7 bits (143), Expect = 7e-09
Identities = 123/542 (22%), Positives = 172/542 (31%), Gaps = 115/542 (21%)
Query: 90 ERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALK 149
E+ S + +E + +D D D +D+ N E A +DE EE ++
Sbjct: 1044 EQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIV 1103
Query: 150 TKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEE------------------------ 185
T + AT+SS + S + ++ P SS +EE
Sbjct: 1104 TSK---AEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMAS 1160
Query: 186 ------------------------LQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESK 221
L ++ + + E EER D+ L + +EE
Sbjct: 1161 AGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPA 1220
Query: 222 RETGGKEESSLMDLADVFTAPAP-------APTTDPWGGP---------APMAAAVPTAA 265
EE L + +P P P P P PM +P
Sbjct: 1221 DSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQP 1280
Query: 266 PTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVD---PWGGTPAPAAGEGPT 322
P P PP PP+ P P P + D P+ P P + P + + +
Sbjct: 1281 PLPPP--RPPRPPS------PPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQS 1332
Query: 323 PDPWGSSDGGVP-----VSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDE 377
+ ++ GG P SG S S P P FS P SP+ ++GG P
Sbjct: 1333 TETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYP-APSPS------LSSGGLPRTPGR 1385
Query: 378 FSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAV----GSPPPAA 433
F PT +G L L +P G D G LA V G P P
Sbjct: 1386 DFSF------TPTFSEPSGPLLLPVCPLPT---GRRDERS--GPLASPVLLETGLPLPLP 1434
Query: 434 TPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNP 493
P P P P A L L+ P + P P P P + S+ P
Sbjct: 1435 LPLPLP--LALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGP 1492
Query: 494 FQPAPPATLTLNQLRLSPVPPVPGAPPTYISPL--------GGGPGLPPMMPPGPPAPNT 545
P +L L P P P+ P G P PP +PP PP P
Sbjct: 1493 LVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPP 1552
Query: 546 NP 547
P
Sbjct: 1553 PP 1554
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/207 (23%), Positives = 71/207 (34%), Gaps = 35/207 (16%)
Query: 165 VGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRET 224
+G GP P E P +G ++AL + + E++ G +++
Sbjct: 588 LGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEG-------------QQS 634
Query: 225 GGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWG 284
G++ M+++D AP + D P PM AA + P +P P
Sbjct: 635 SGED----MEISDDEMPSAPITSADC---PKPMVVTPGAAAVAAPSVLAPTLPLPPPPGF 687
Query: 285 GPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPW 344
P P P P +P P P + P P PA P P + GVP P P
Sbjct: 688 PPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVP--PPPILPPL 745
Query: 345 TPAP-------------AFSDPWGGSP 358
P P WGG P
Sbjct: 746 PPFPPGLFPVMQVDMSHVLGGQWGGMP 772
Score = 32.0 bits (71), Expect = 1.5
Identities = 31/96 (32%), Positives = 39/96 (40%), Gaps = 33/96 (34%)
Query: 468 TPPGAKASNPFLPGGGPATG-PSVTNPFQ------PAPPATLTLN---------QLRLSP 511
TPP A+A+ PA G S +P+Q P PP T + R +P
Sbjct: 381 TPPPAQAT--------PAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAP 432
Query: 512 VPP-VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTN 546
PP +P A P P PPGPP P+TN
Sbjct: 433 APPPLPPAEPLAKEK--------PGTPPGPPPPDTN 460
>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
Length = 411
Score = 72.0 bits (175), Expect = 1e-12
Identities = 91/325 (28%), Positives = 123/325 (37%), Gaps = 46/325 (14%)
Query: 241 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGP------PVPPAADPWGGPAPTPASGD 294
A A AP P G + AA PT WGGP +P A P GP P P G
Sbjct: 50 ASASAPQRGPSG---ILPAAEPTICSLHQAWGGPGCRAQKGIPAALSPGPGPIPAPIPG- 105
Query: 295 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPW 354
PA GP G P P G P P + P+ GP + P P F P
Sbjct: 106 ---PAQIPGPLP---GSIPGPIPGPAQIPSPIPA-----PIPGPISGPVQIPGP-FRGPI 153
Query: 355 GGSPAKPS-TNGTTAGGFD-TEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 412
G + P+ G +G F P + P SG G + + +P PG
Sbjct: 154 PGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGPIPGPISV---PIPGPIPGP 210
Query: 413 FDMSGVRGSLAEAVGSPPPAATPTPT--PPTRKTPESFLGPNAALV--DLDSLVSRPGPT 468
+ G ++ P P P P P P GPN L+ + +S PGP
Sbjct: 211 -----ISGPISGPNPGPIPGPIPGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPI 265
Query: 469 PPGAKASNPFLPGGGPATGPS-VTNPFQPAPPATLTLNQLRLSPVPPVPGAPP---TYIS 524
G S +PG G GP + +P + P +L L+P+ PG+ P + +
Sbjct: 266 -IGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLP----GLAPILG-PGSGPGSGSVPA 319
Query: 525 PLGGGPGLPPMMPPGPPAPNTNPFL 549
P+ G LP P P +P+ + FL
Sbjct: 320 PIPGPGSLPAPAPLWPQSPDASDFL 344
Score = 65.9 bits (159), Expect = 9e-11
Identities = 88/315 (27%), Positives = 110/315 (34%), Gaps = 54/315 (17%)
Query: 255 APMAAAVPTAAPTSDPWGGPPVPPAADP--------WGGPAPTPASGDPWRPAAPAGPSV 306
AP+ A +AP P G + PAA+P WGGP G P A GP
Sbjct: 44 APLVPAASASAPQRGPSG---ILPAAEPTICSLHQAWGGPGCRAQKGIP--AALSPGP-- 96
Query: 307 DPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGT 366
G PAP G P P S G P+ GP+ PAP P G P
Sbjct: 97 ---GPIPAPIPGPAQIPGPLPGSIPG-PIPGPAQIPSPIPAP-IPGPISGPVQIPGPFRG 151
Query: 367 TAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAV 426
G + P P SG +G G +P +PG + G ++ +
Sbjct: 152 PIPGPISGPAPIPG--------PISGPFSGP---NPGPIPGPNPGP-----IPGPISGPI 195
Query: 427 GSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVS--RPGPTPPGAKASNPFL---PG 481
P P P P P S P + +S PGP P NP L P
Sbjct: 196 PGPISVPIPGPIPGPISGPISGPNPGPIPGPIPGPISGPNPGPIPGPISGPNPGLIPGPI 255
Query: 482 GGPATGPS-----VTNPFQPAPPATL-----TLNQLRLSPVPPVPGAPPTYISPLGGGPG 531
GP +GP + +P Q P L L+ R+ +PG P G G G
Sbjct: 256 PGPISGPGPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLPGLAPILGPGSGPGSG 315
Query: 532 LPPMMPPGP---PAP 543
P PGP PAP
Sbjct: 316 SVPAPIPGPGSLPAP 330
Score = 56.6 bits (135), Expect = 6e-08
Identities = 69/254 (27%), Positives = 87/254 (34%), Gaps = 51/254 (20%)
Query: 241 APAPAPTTDPWGGPA------------PMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAP 288
+P PAP P GP P++ P P S P+ GP P P GP P
Sbjct: 129 SPIPAPIPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIP 188
Query: 289 TPASGDPWRPAAPAGPSVDPWGGTPAPAAG--EGPTPDPWGSSDGGVPVSGPSASDPWTP 346
P SG P SV G P P +G GP P P G P+SGP+ P
Sbjct: 189 GPISG-----PIPGPISVPIPGPIPGPISGPISGPNPGPIPGPIPG-PISGPN------P 236
Query: 347 APAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVP 406
P G +P G G P S + +P+ G L G P
Sbjct: 237 GPIPGPISGPNP------GLIPGPI---PGPISGPGPIIGPIPSPAQIPGP-GRLQGPGP 286
Query: 407 ARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPG 466
SPG G LA +G P P + P GP + + P
Sbjct: 287 ILSPGRMRSPGSLPGLAPILG-------PGSGPGSGSVPAPIPGPGS--------LPAPA 331
Query: 467 PTPPGAKASNPFLP 480
P P + ++ FLP
Sbjct: 332 PLWPQSPDASDFLP 345
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 71.2 bits (173), Expect = 2e-12
Identities = 79/285 (27%), Positives = 105/285 (36%), Gaps = 30/285 (10%)
Query: 272 GGPPVPPAADPWGGPAPTPASGDPWRPAAPAG----PSVDPWGGTPAPAAGEGPTPD-PW 326
G PVP + GPA TP + P RPAAPA PS+ + P GP+ P+
Sbjct: 321 GEAPVPASVGSTSGPATTPLASAP-RPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
Query: 327 GSSDGGVPVSGPSASDPWT---PAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDR 383
GG P G P + P P+ + GG P + + NG P +
Sbjct: 380 HGMHGGGP--GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPH 437
Query: 384 LRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAAT--PTPTPPT 441
P ++ G P S G + + +G + PPP P P PP+
Sbjct: 438 -----PPGHHGPPPMDQYLGSTPVGS-GVYRLHQGKGMMP-----PPPMGMMPPPPPPPS 486
Query: 442 RKTPESFLGPNAALVDLDSLVSRPGPTPP--GAKASNPFLPGGGPATGPSVTNPFQPAPP 499
+ P GP L +P P PP + AS+ LP T + + PP
Sbjct: 487 GQPPPPPSGP---LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPP 543
Query: 500 ATLTLNQLRLSP-VPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 543
SP P + G P P G P LPP PP PP P
Sbjct: 544 WQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPP 588
Score = 45.8 bits (107), Expect = 1e-04
Identities = 92/356 (25%), Positives = 110/356 (30%), Gaps = 109/356 (30%)
Query: 227 KEESSLMDLADVFTAPAPAPTTDPWGGPA--PMAAAVPTAAPTSDP-------------- 270
KE SLM A++ AP PA + GPA P+A+A AAP ++P
Sbjct: 311 KEYLSLM--AELGEAPVPA-SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPP 367
Query: 271 W---------------GGPPVPPAADPWGGPAPTPA-----SGDPWRPAAPAGPSVDPWG 310
W GG P P P P P P+ G P + P GP PW
Sbjct: 368 WMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQ-HNPNGPP-PPWM 425
Query: 311 GTPAPAAGEGP------TPDPWGSSDGGVPV----------SGPSASDPWTPAPAFSDPW 354
P P +GP P P G PV G P P P
Sbjct: 426 QPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP 485
Query: 355 GGSPAKPSTNGTTAGGFDTE----PDEFSDFDRLRTALP------TSGSSAGELELLAGE 404
G P P + + P S T LP T+ +SAG G
Sbjct: 486 SGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAG-----TGS 540
Query: 405 VP---------ARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAAL 455
+P A SPGA M G + G PP P PP
Sbjct: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPP--------------- 585
Query: 456 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSP 511
P PP A P GG GPS + P P TL Q + P
Sbjct: 586 -----------PPPPPGSAGMMIPPRGG--DGPSHESEDFPRPLVTLPGRQPQQRP 628
Score = 32.7 bits (73), Expect = 0.88
Identities = 31/98 (31%), Positives = 36/98 (36%), Gaps = 12/98 (12%)
Query: 240 TAPAPAPTTDPWGGPAPMAAAVPTAA-----PTS---DPWGGPPVPPAADPWGGPAPTPA 291
T A + PW AAA P A PT P PP+PP A P P P +
Sbjct: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGS 592
Query: 292 SGDPWRPAAPAGPSVDPWGGTPAPAA---GEGPTPDPW 326
+G P GPS + P P G P PW
Sbjct: 593 AGMMIPPRGGDGPSHES-EDFPRPLVTLPGRQPQQRPW 629
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 70.5 bits (171), Expect = 4e-12
Identities = 81/327 (24%), Positives = 113/327 (34%), Gaps = 68/327 (20%)
Query: 240 TAPAPAPTT----DPWGGPAPMAAAVPTAAPTSDPWGGPPV-----PPAADPWGGPAPTP 290
T P+P PT+ P P+P T PT+ P PP+ PP P T
Sbjct: 1404 TTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTP--SPPITTTTTPPPTTTPSPPISTT 1461
Query: 291 ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
+ P +P + P TP+P TP P + S P+ + PA
Sbjct: 1462 TTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP------SPPTTTPITPPASTT 1515
Query: 351 SDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 410
+ P +P+ P+T TT T S PTS ++ P +P
Sbjct: 1516 TLPPTTTPSPPTTTTTTPPPTTTP----SPPTTTPITPPTSTTTL---------PPTTTP 1562
Query: 411 GAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 470
SPPP T TP P T +P + P+ + + P+PP
Sbjct: 1563 -----------------SPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPP 1605
Query: 471 GA------KASNPFLPGGGPATGPSVTNPF----QPAPPATLTLNQLRLSPVPPVPGAPP 520
+ P P P T P+ T P+PP T T +P P +PP
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT-----TTPPPTTTPSPP 1660
Query: 521 TYISPLGGGPGLPPMMPPGPPAPNTNP 547
T +P PP+ P P T P
Sbjct: 1661 TTTTP------SPPITTTTTPPPTTTP 1681
Score = 63.5 bits (153), Expect = 5e-10
Identities = 74/318 (23%), Positives = 106/318 (33%), Gaps = 51/318 (16%)
Query: 240 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 299
T P+P PTT P PA PT P+ PP P P+P + P P
Sbjct: 1498 TTPSP-PTTTPITPPASTTTLPPTTTPS------PPTTTTTTPPPTTTPSPPTTTPITP- 1549
Query: 300 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPA 359
P + P TP+P TP P + S P+ + P P + P +
Sbjct: 1550 -PTSTTTLPPTTTPSPPPTTTTTPPPTTTP------SPPTTTTPSPPTITTTTPPPTTTP 1602
Query: 360 KPSTNGTTAGGFDTEPDEFSDFD----RLRTALPTSGSSAGELELLAGEVPARSPGAFDM 415
P T TT T P + T LP + + + P +P
Sbjct: 1603 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP----- 1657
Query: 416 SGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDS----LVSRPGPTP-P 470
SPP TP+P T TP P++ + S ++ P PT P
Sbjct: 1658 ------------SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP 1705
Query: 471 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 530
+ + P P T P+P T + ++ +PP + P +PL
Sbjct: 1706 SSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL---- 1761
Query: 531 GLPPMMPPGPPAPNTNPF 548
PP P +PF
Sbjct: 1762 ------PPSITPPTFSPF 1773
Score = 43.1 bits (100), Expect = 7e-04
Identities = 75/338 (22%), Positives = 104/338 (30%), Gaps = 38/338 (11%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 3925 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3984
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3985 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4041
Query: 351 SDPW-------GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 403
+ G+ +T TT P T + T+ +
Sbjct: 4042 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4101
Query: 404 EVPARSPGAFDMSGVRGSLAEAVGSPPPAATP-------TPTPPTRKTPESFLGPNAALV 456
+ P +P + G+ P TP TPTP TP P +
Sbjct: 4102 QTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPI 4155
Query: 457 DLDSLVSRPGPTPPGAKA--SNPFLPGGG--PATGPSVTNPFQPAPPATLTLNQLRLSPV 512
+ V+ P PTP G + + P P P+ T P +T + +L S
Sbjct: 4156 TTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNP 4214
Query: 513 PPVPGAPPT---YISPLGGGPGLPPMMPPGPPAPNTNP 547
PP P T SPL L +PP +T P
Sbjct: 4215 PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAP 4252
Score = 41.6 bits (96), Expect = 0.002
Identities = 59/284 (20%), Positives = 79/284 (27%), Gaps = 12/284 (4%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 4017 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4076
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 4077 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4133
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 4134 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4193
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
+AE S PP + TP +R T L L + P
Sbjct: 4194 QTGPPTHTSTAPIAELTTSNPPPESSTPQT-SRSTSSPLTESTTLLSTLPPAIEMTSTAP 4252
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVP 513
P + GG + P T P P T +P P
Sbjct: 4253 PSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTP 4296
Score = 41.2 bits (95), Expect = 0.002
Identities = 75/341 (21%), Positives = 103/341 (30%), Gaps = 41/341 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWR 297
+ T P+P TT P ++ T T P PP P TP+
Sbjct: 1685 ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTM 1744
Query: 298 PAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPA--PAFSDPWG 355
P + P TP P + PT P+ ++ P W + P F P G
Sbjct: 1745 TTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGG 1804
Query: 356 -----GSPAKPSTNGTTAGGFDTEPD-EFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
G P + PD + + G + G V
Sbjct: 1805 DTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV---I 1861
Query: 410 PGAFDMS-GVRGSLAEAVGSPPPAATPT---PTPPT------------RKTPESFLGPNA 453
P AF ++ + E V P T T PTPPT TP P
Sbjct: 1862 PMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTT 1921
Query: 454 ALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQL 507
+ + V+ P PTP G + P P T + P P P T T
Sbjct: 1922 TPITTTTTVT-PTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTT 1974
Query: 508 RLSPVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 547
++P P G +P+ + P P G P T P
Sbjct: 1975 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2015
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 1947 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2006
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2007 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2063
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 2064 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 2119
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 2120 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 2166
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 2167 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2220
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 2221 TPITTTTTVTPTPTPTGTQTPTTTP 2245
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 2062 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2121
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2122 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2178
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 2179 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 2234
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 2235 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 2281
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 2282 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2335
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 2336 TPITTTTTVTPTPTPTGTQTPTTTP 2360
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 2177 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2236
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2237 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 2349
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 2350 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 2396
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 2397 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2450
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTP 2475
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 2292 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2351
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2352 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 2464
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 2465 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 2511
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 2512 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2565
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTP 2590
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 2407 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2466
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2467 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 2579
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 2580 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 2626
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 2627 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2680
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTP 2705
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 2522 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2581
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2582 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2638
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 2694
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 2695 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 2741
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 2742 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2795
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTP 2820
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 2637 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2696
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2697 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 2809
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 2810 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 2856
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 2857 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2910
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTP 2935
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 2752 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2811
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2812 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 2924
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 2925 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 2971
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 2972 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTP 3050
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 2867 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2926
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2927 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2983
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 2984 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 3039
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 3040 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 3086
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 3087 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3140
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 3141 TPITTTTTVTPTPTPTGTQTPTTTP 3165
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 2982 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3041
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3042 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3098
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 3154
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 3155 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 3201
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 3202 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3255
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTP 3280
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 3097 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3156
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3157 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 3269
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 3270 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 3316
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 3317 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3370
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTP 3395
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 3212 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3271
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3272 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 3384
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 3385 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 3431
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 3432 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3485
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 3486 TPITTTTTVTPTPTPTGTQTPTTTP 3510
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 3327 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3386
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3387 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3443
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 3444 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 3499
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 3500 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 3546
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 3547 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3600
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 3601 TPITTTTTVTPTPTPTGTQTPTTTP 3625
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 3442 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3501
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3502 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3558
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 3614
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 3615 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 3661
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 3662 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3715
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 3716 TPITTTTTVTPTPTPTGTQTPTTTP 3740
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 3557 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3616
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3617 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3673
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 3729
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 3730 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 3776
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 3777 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 3831 TPITTTTTVTPTPTPTGTQTPTTTP 3855
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 3672 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3731
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3732 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3788
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 3789 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 3844
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 3845 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 3891
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 3892 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3945
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 3946 TPITTTTTVTPTPTPTGTQTPTTTP 3970
Score = 40.0 bits (92), Expect = 0.006
Identities = 71/325 (21%), Positives = 97/325 (29%), Gaps = 41/325 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 3787 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3846
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3847 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3903
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 3904 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 3959
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 3960 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 4006
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 4007 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4060
Query: 524 SPLGGGPGLPPM-MPPGPPAPNTNP 547
+P+ + P P G P T P
Sbjct: 4061 TPITTTTTVTPTPTPTGTQTPTTTP 4085
Score = 37.7 bits (86), Expect = 0.027
Identities = 78/349 (22%), Positives = 111/349 (31%), Gaps = 52/349 (14%)
Query: 240 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPAS--GDPWR 297
T P+P TT P PT P+S P P P TP+S
Sbjct: 1655 TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTT 1714
Query: 298 PAAPAGPSVDPWG-GTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGG 356
P++ PS P TP+P TP P ++ +P + S+ TP P P
Sbjct: 1715 PSSTTTPSPPPTTMTTPSPTT----TPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTF 1770
Query: 357 SPAKPSTNGTT-------AGGFDTEPDEF----SDFDRLRTAL-PTSGSSAGELELLAGE 404
SP +T T G D+ F D + + P ++ + +
Sbjct: 1771 SPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPD 1830
Query: 405 VPARSPGAFDMSGVR-GSLAEAVGSPPPAATP------------------TPTPPTRKTP 445
VP G + V G + + P P PT T T
Sbjct: 1831 VPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTT 1890
Query: 446 ESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT-- 503
E+ P + + V+ P PTP G + P P T + P P P T T
Sbjct: 1891 ENPTPPTTTPITTTTTVT-PTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPT 1943
Query: 504 ----LNQLRLSPVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 547
++P P G +P+ + P P G P T P
Sbjct: 1944 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992
Score = 37.4 bits (85), Expect = 0.036
Identities = 70/324 (21%), Positives = 96/324 (29%), Gaps = 42/324 (12%)
Query: 238 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 291
+ T PT P G P + T PT P G P P PTP
Sbjct: 3902 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3961
Query: 292 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3962 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4018
Query: 351 SDPW-GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 409
+ +P T T T T PT+ + P +
Sbjct: 4019 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVTPTPT 4074
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
P +G + + + TPTPTP +TP + V P PTP
Sbjct: 4075 P-----TGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTP 4121
Query: 470 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVPPVPGAPPTYI 523
G + P P T + P P P T T ++P P G
Sbjct: 4122 TGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4175
Query: 524 SPLGGGPGLPPMMPPGPPAPNTNP 547
+P+ + P P P T P
Sbjct: 4176 TPITTTTTVTP--TPTPTGTQTGP 4197
Score = 34.3 bits (77), Expect = 0.30
Identities = 57/275 (20%), Positives = 80/275 (29%), Gaps = 29/275 (10%)
Query: 288 PTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPA 347
PTP + P P TP P + PT P ++ P P+ + T
Sbjct: 1893 PTPPTTTPITTTTTVTP-------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1945
Query: 348 P-AFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVP 406
P + +P T T T T PT+ + P
Sbjct: 1946 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2005
Query: 407 ARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPT-------RKTPESFLGPNAALVDLD 459
+ + +P TPT TP T TP P +
Sbjct: 2006 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2065
Query: 460 SLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLSPVP 513
+ V+ P PTP G + P P T + P P P T T ++P P
Sbjct: 2066 TTVT-PTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTP 2118
Query: 514 PVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 547
G +P+ + P P G P T P
Sbjct: 2119 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 70.5 bits (171), Expect = 4e-12
Identities = 125/509 (24%), Positives = 178/509 (34%), Gaps = 93/509 (18%)
Query: 26 EATSNDPWGPSSSLMSEIADLTYNVVA--FSEIMSMIWKRLNDHGKNWRHVYKAMTLMEY 83
EA S + P S +E+A + N + E M K L +HG+NW + + +
Sbjct: 589 EANSEEAITPQQS--AELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMV----- 641
Query: 84 LIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREE 143
GS+ VSQ CK N Y F Y R D+ + + +L+ E
Sbjct: 642 ----GSKTVSQ-CK-NFY-------FNYKKRQNLDE--------------ILQQHKLKME 674
Query: 144 RAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQEE 203
+ + K+K A A + AA PP E ++SG ++EE
Sbjct: 675 KERNARRKKKKAPAAASEEAAF----PPVVEDEEMEASGVS--------------GNEEE 716
Query: 204 RIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAP---APTTDPWGGPAPMAAA 260
+ + L E + E G +++ + +D + P+P A GP P
Sbjct: 717 MVEEAEALHAS-GNEVPRGECSGP--ATVNNSSDTESIPSPHTEAAKDTGQNGPKP---- 769
Query: 261 VPTAAPTSDPWGGPPVPPAADPWGGPAPTPAS---GDPWRPAAPAGPSVDPWGGTPAPAA 317
P P GPP PP D PTPAS G P P AP PS P P
Sbjct: 770 -PATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPP-PVVPKEEK 827
Query: 318 GEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDE 377
E P + G P+A + +P + + G A G D E E
Sbjct: 828 EEETAAAP--PVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEG-PAKGKDAEAAE 884
Query: 378 FSDFDRLRTALPTSGSSAGELELLAG----EVPARSPGAFDMSGVRGSLAEAVGSPPPA- 432
+ L+ GS +G + + A ++ G + SP P+
Sbjct: 885 ATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSL 944
Query: 433 ATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP-GAKASNPFLPGGGPATGPSVT 491
TPT P +P+ L DL L R PP K P P + T
Sbjct: 945 LTPTGDPRANASPQKPL-------DLKQLKQRAAAIPPIVTKVHEP------PREDAAPT 991
Query: 492 NPFQPAPPATLTLNQLRLSPVPPVPGAPP 520
P PAPP L S P PG+ P
Sbjct: 992 KPAPPAPPPPQNLQP--ESDAPQQPGSSP 1018
Score = 33.5 bits (75), Expect = 0.52
Identities = 83/356 (23%), Positives = 113/356 (31%), Gaps = 67/356 (18%)
Query: 151 KEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDD 210
+EK +TA A G P A + +G+ E ++ EE + + +
Sbjct: 825 EEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAE 884
Query: 211 LRLQMAIEESKRETGG-------------KEESSLMDLADV-----------FTAPAPA- 245
+ A++ K+E G +SS AD +P P+
Sbjct: 885 ATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSL 944
Query: 246 --PTTDPWGGPAPM-----------AAAVPT------------AAPTSDPWGGPPVPPAA 280
PT DP +P AAA+P AAPT PP P
Sbjct: 945 LTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNL 1004
Query: 281 DPWGGPAPTPAS---GDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSG 337
P P S G PA PA + PA AA P G+P
Sbjct: 1005 QPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPV 1064
Query: 338 PS----ASDPWTPAP-AFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSG 392
P + P P P AFS G P P TA P S+ P
Sbjct: 1065 PPREVIKASPHAPDPSAFSYAPPGHPL-PLGLHDTARPVLPRPPTISN-------PPPLI 1116
Query: 393 SSAGELELLAGEVPARSPG-AFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPES 447
SSA +L ++ A S G + + A+A P P P P + P S
Sbjct: 1117 SSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFS 1172
Score = 32.0 bits (71), Expect = 1.5
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 5/60 (8%)
Query: 466 GPTPPGAKASNPFLPGGGPATGP--SVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYI 523
GP PP ++ P GP T P + P +P P + T P PP P APP +
Sbjct: 766 GPKPPATLGADG--PPPGPPTPPPEDIPAPTEPTPASEAT-GAPTPPPAPPSPSAPPPVV 822
Score = 32.0 bits (71), Expect = 1.5
Identities = 49/191 (25%), Positives = 63/191 (32%), Gaps = 34/191 (17%)
Query: 343 PWTPAPAFSDPWGGSPAKPS-----TNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGE 397
P P P FS SP P T TT + E D + DR R + +S
Sbjct: 1769 PTAPQP-FSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTT 1827
Query: 398 LELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVD 457
+E P PG SG GS GS + P + S + P
Sbjct: 1828 VE----HAPIWRPGTEQSSGSSGSSGGGGGS-----SSRPASHSHAHQHSPISPRTQ--- 1875
Query: 458 LDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPG 517
D+L RP + N + G + +P+ P L SPV P
Sbjct: 1876 -DALQQRP------SVLHNTGMKG--------IITAVEPSTPTVLRSTSTS-SPVRPAAT 1919
Query: 518 APPTYISPLGG 528
PP PLGG
Sbjct: 1920 FPPATHCPLGG 1930
Score = 31.6 bits (70), Expect = 2.0
Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 496 PAPPATLTLNQLRLSPVPPVPG--APPTYISPLGGGPGLPPMMPPGPPAPNTNP 547
P PPATL + P P P PT +P G P PP PP+P+ P
Sbjct: 767 PKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATG-APTPPPAPPSPSAPP 819
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 69.7 bits (169), Expect = 7e-12
Identities = 98/325 (30%), Positives = 115/325 (35%), Gaps = 71/325 (21%)
Query: 249 DPWGGPAPMAAAVPTAAP--TSDPWGGPPVPPAADPWGGPAPTPASGD----PWRPAAP- 301
DP G PAP A P+ P S+ W P + PA P+ PA + ASG W P
Sbjct: 590 DP-GVPAPQAPQAPSEVPQLVSETWASP-LFPAPRPF--PAQSSASGSFLLSGWDPEGRG 645
Query: 302 AGPSVDPWGGTPAPAAGEGPTPDPW---------GSSDGGVPVS---GPSASDPWTPAPA 349
AG ++ G PA GE T PW GSS G S GPS P P P
Sbjct: 646 AGETL---AGDPAEVLGERGTA-PWVEEEEEEEEGSSPGEDSSSLGGGPSRRGP-LPCPL 700
Query: 350 FSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSA-----GELELLAGE 404
S G P G G+ P L P S+ G L L
Sbjct: 701 CSRE-GACSCLPLERGDAVAGWGGHP-------ALGCPHPPEDDSSLRAERGSLADLPMA 752
Query: 405 VPARSPGAF--DMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLV 462
PA +P F + G G PP P P P P + P +A+ S +
Sbjct: 753 PPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGL 812
Query: 463 SRPGPTP--PGAKASNPF-----LPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPV 515
S PGP P G + PF PGGG A V P R P PP
Sbjct: 813 SSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRP--------------RAPPEPPD 858
Query: 516 PGAPPTYISPLGGGPGLPPMMPPGP 540
PGAP P P+ PGP
Sbjct: 859 PGAPRP-------PPDPGPLPLPGP 876
Score = 54.7 bits (130), Expect = 2e-07
Identities = 86/349 (24%), Positives = 115/349 (32%), Gaps = 57/349 (16%)
Query: 242 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPAS--------G 293
P P P P+ P P A + P S P+ P ADP T +S
Sbjct: 451 PPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLW 510
Query: 294 DPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWG---SSDGGVPV---SGPSASDPW--- 344
+ R A G W AP A +P+ S+ +PV PS S +
Sbjct: 511 EKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIR 570
Query: 345 ------TPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEF------SDFDRLRTALPTSG 392
P P F + W P P A +E + S P
Sbjct: 571 LEEHGSPPEPLFPNDW--DPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQS 628
Query: 393 SSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPN 452
S++G L + R G + G AE +G A P + E P
Sbjct: 629 SASGSFLLSGWDPEGRGAG----ETLAGDPAEVLGERGTA----PWVEEEEEEEEGSSPG 680
Query: 453 AALVDLDSLVSRPGPTP------PGAKASNPFLPG---GGPATGPSVTNPFQPAPPATLT 503
L SR GP P GA + P G G P++ P P ++L
Sbjct: 681 EDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLR 740
Query: 504 LNQLRLSPVPPVP--GAPPTYISPLGG-------GPGLPPMMPPGPPAP 543
+ L+ +P P APP ++ PL G G G PP PP PP P
Sbjct: 741 AERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPP 789
Score = 54.7 bits (130), Expect = 2e-07
Identities = 75/282 (26%), Positives = 92/282 (32%), Gaps = 53/282 (18%)
Query: 277 PPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAG--EGPTPDPWGSSDGGVP 334
PP PW P P + + W PA P G PAP P P SS G
Sbjct: 1047 PPETGPWRAPGPWEKTPESWGPA--------PTIGEPAPETSLERAPAPSAVVSSRNG-- 1096
Query: 335 VSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSS 394
G +A P PAP NGT G + E R A S
Sbjct: 1097 --GETAPGPLGPAP--------------KNGTLEPGTERRAPETGGAPRAPGAGRLDLGS 1140
Query: 395 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATP----------TPTPPTRK- 443
G + G P PG+ + G + PPP P P PP +
Sbjct: 1141 GGRAPVGTGTAPGGGPGS-GVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARP 1199
Query: 444 --TPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQ---PAP 498
PE G + D+ +S G PP + P +P GP N Q
Sbjct: 1200 EVAPEGEPGAPDSRAGGDTALSGDG-DPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLS 1258
Query: 499 PATLTLNQLRLSPVP-PVPGAPPTYISPLG------GGPGLP 533
+L L L L+P P P P PP + G GG G P
Sbjct: 1259 RLSLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAP 1300
Score = 45.1 bits (105), Expect = 2e-04
Identities = 75/334 (22%), Positives = 92/334 (27%), Gaps = 67/334 (20%)
Query: 242 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAP 301
P P P P + A P A P P G P P + GG GDP +P
Sbjct: 1175 PPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRA--GGDTALSGDGDPPKPERK 1232
Query: 302 AGPSVD--------PWGG------------------TPAPAAGEGPTPDPWGSSDGGVPV 335
GP + P G T P G GP PW +D G
Sbjct: 1233 -GPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGA-- 1289
Query: 336 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSA 395
+G A P PA D G D + DE D +
Sbjct: 1290 AGGEAGGAGAPGPAEED-----------------GEDEDEDEEEDEEAAAPGAAAGPRGP 1332
Query: 396 GELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPT-------------- 441
G V S A +RG L G+ P +
Sbjct: 1333 GRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFD 1392
Query: 442 RKTPESFLGPNAALV-DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVT----NPFQP 496
++TP + L A D D PTPP P G S P P
Sbjct: 1393 QETPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLLP 1452
Query: 497 APPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 530
P L ++ +SP PG P GP
Sbjct: 1453 PPGPPLCFSRFSVSPALETPGPPARAPDARPAGP 1486
Score = 43.9 bits (102), Expect = 4e-04
Identities = 91/391 (23%), Positives = 116/391 (29%), Gaps = 88/391 (22%)
Query: 228 EESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPP--------- 278
E SL DL A AP DP G AA P GPP P
Sbjct: 742 ERGSLADLPMAPPASAPPEFLDPLMG----------AAAPQYPGRGPPPAPPPPPPPPRA 791
Query: 279 AADPWGGPAPTPASGDPWRPAAPAGPSVDPWG-GTPAPAAGEGPTPDPWGSSDGGV--PV 335
ADP P P A P + GP G T P + EG P + + GV P
Sbjct: 792 PADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPR 851
Query: 336 SGPSASDPWTPAPAFSD---PWGGSPAKPS------------------------------ 362
+ P DP P P P G KP+
Sbjct: 852 APPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATA 911
Query: 363 --TNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPA------RSPGAFD 414
T AG ++ +R T L +G A L L V R+PG +
Sbjct: 912 RETGPRKAGRGPGNREKVPGLNRDPTVL-GNGKQAPSLSLPVNGVTVLENGDQRAPGIEE 970
Query: 415 MSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKA 474
+ G+L TPP R+ G + + ++ G TPP K+
Sbjct: 971 KAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPP--KS 1028
Query: 475 SNPFLPGGG----------PATGP--------SVTNPFQPAPPATLTLNQLRLSPVPPVP 516
+ GG P TGP + PAP + L P
Sbjct: 1029 EDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAP--- 1085
Query: 517 GAPPTYISPLGGGPGLPPMMPPGPPAPNTNP 547
AP +S GG P + P P P
Sbjct: 1086 -APSAVVSSRNGGETAPGPLGPAPKNGTLEP 1115
Score = 41.2 bits (95), Expect = 0.002
Identities = 97/404 (24%), Positives = 114/404 (28%), Gaps = 102/404 (25%)
Query: 213 LQMAIEESKRETGGKEES---SLMDLADVFTAPAPAPTTDPWGGPAP----MAAAVPTAA 265
L+ E ETGG + +DL AP T P GGP A V
Sbjct: 1113 LEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTA-PGGGPGSGVDAKAGWVDNTR 1171
Query: 266 PTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDP 325
P P PP P A PAP A + P P G T G+ P P+
Sbjct: 1172 PQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPER 1231
Query: 326 WGSS------DGGVPVSGPS-----------ASDPWTPAPAFSDPWGGSPAKPSTNGTTA 368
G D G P A P T P F P P +P G A
Sbjct: 1232 KGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTP-FPGP---GPRRPPWEGADA 1287
Query: 369 G------------------GFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 410
G G D + DE D + G V S
Sbjct: 1288 GAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSA 1347
Query: 411 GAFDMSGVRGSLAEAVGSPPP------------------------AATPTPTPPTRKTPE 446
A +RG L G+ P TPT + PE
Sbjct: 1348 DADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPE 1407
Query: 447 SFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGG-PATGPSVTNPFQPAPPATLTLN 505
D D PTPP +P PG G P+ F+ A
Sbjct: 1408 G---------DTDPSTPPAPPTPP-----HPATPGDGFPSNDSGFGGSFEWAED------ 1447
Query: 506 QLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPP--APNTNP 547
P+ P PG PP S P L PGPP AP+ P
Sbjct: 1448 ----FPLLPPPG-PPLCFSRFSVSPALE---TPGPPARAPDARP 1483
Score = 40.4 bits (93), Expect = 0.004
Identities = 79/307 (25%), Positives = 105/307 (34%), Gaps = 41/307 (13%)
Query: 218 EESKRETGGK--EESSLMDLADVFTAPAPAPTTDPWGGPA--PMAAAVPTAAPTSDPWGG 273
EE + E G E+SS + P P P G + P+ A P G
Sbjct: 669 EEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALG 728
Query: 274 PPVPPAADPWGGPAPTPASGDPWRPAAPAGPS-VDPWGGTPAPA-AGEGPTPDPWGSSDG 331
P PP D + P P A A P +DP G AP G GP P P
Sbjct: 729 CPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPP 788
Query: 332 GVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTS 391
+ P+AS P A + P G + G + G++TE FS A P
Sbjct: 789 PRAPADPAASPD--PPSAVASPGSGLSSPGPKPGDS--GYETETP-FSP----EGAFPGG 839
Query: 392 GSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESF--L 449
G++ E P P D R PPP P P P R+ P +
Sbjct: 840 GAAEEE----GVPRPRAPPEPPDPGAPR---------PPPDPGPLPLPGPREKPTFVVQV 886
Query: 450 GPNAALVDLDSLVSRP--GPTPPGAKASNPFLPGGGPAT---------GPSVTNPFQPAP 498
L+ L V+R G A+ + P G GP P+V + AP
Sbjct: 887 STEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQAP 946
Query: 499 PATLTLN 505
+L +N
Sbjct: 947 SLSLPVN 953
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 69.3 bits (168), Expect = 9e-12
Identities = 89/355 (25%), Positives = 118/355 (33%), Gaps = 66/355 (18%)
Query: 239 FTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPP---AADPWGGPAPTPASGDP 295
F +P T P+ A+ P + P P P PP + P P +P + P
Sbjct: 429 FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488
Query: 296 WR---------PAAP---------------AGPSVD-PWGGTPAPAAGEGPTPDPWGSSD 330
+ P AP A PS+ P P P+ P
Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548
Query: 331 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGT-TAGGFDTEPDEFSDFDRLRTALP 389
P++ P P PAP P P+ +T T T P + + P
Sbjct: 549 ASAPLTTPHLETPPCPAPC---PLQAPPSPLTTPPPETPSSIATPPPQAPP---ALASPP 602
Query: 390 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFL 449
G + L LA P P +L P P A+P +P +P++
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXL--------ALPPLQAPPSPPASPPLSPLATPSPQA-- 652
Query: 450 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQ-------------P 496
PNA V L P P+PP PF P P PS T P Q P
Sbjct: 653 -PNALAVHLLQAPFSPPPSPP---VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 708
Query: 497 APPATLTLNQLRLSP--VPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFL 549
+PPA+ ++ P PP APP + P P PPM P P P P L
Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPP--SPPASPPMSPSATPPPRVPPLL 761
Score = 65.5 bits (158), Expect = 1e-10
Identities = 88/328 (26%), Positives = 108/328 (32%), Gaps = 81/328 (24%)
Query: 231 SLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTP 290
+L LA A AP T P P A P AP S P P P TP
Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS---------PLTTP---PPETP 584
Query: 291 ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 350
+S P AP + P G P+P TP P +P P A
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALP-----------PLQAP 633
Query: 351 SDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 410
P P P L T P + ++ L A P SP
Sbjct: 634 PSPPASPPLSP----------------------LATPSPQAPNALAVHLLQAPFSPPPSP 671
Query: 411 GAFDMSGVRGSLAEAVGSPP--PAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT 468
+A SPP P +P+ TPP++ P SL + P
Sbjct: 672 P-----------VQAPFSPPASPPVSPSATPPSQAPP--------------SLAAPPLQV 706
Query: 469 PPGAKASNPFLPGGGP---ATGPSVTNPFQ--PAPPATLTLNQLRLSP--VPPVPGAPPT 521
PP AS P P P A P P Q P+PPA+ ++ P VPP+ APP
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766
Query: 522 YISPLGGGPGLPPMMPPGPPAPNTNPFL 549
+ P P PM P P P P L
Sbjct: 767 QVPP--SPPASLPMSPLAKPPPQAPPAL 792
Score = 65.5 bits (158), Expect = 1e-10
Identities = 80/310 (25%), Positives = 101/310 (32%), Gaps = 68/310 (21%)
Query: 241 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA- 299
+P +P P P+P A P+ PP PP P+ PA P S P+
Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 694
Query: 300 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPA 359
AP + P P+P A +P P++ P P P+P S P S
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP--PSPPASPPMSPSAT 752
Query: 360 KPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR 419
P L A P +VP P + MS
Sbjct: 753 PPPR-----------------VPPLLAAPPL-------------QVPPSPPASLPMS--- 779
Query: 420 GSLAEAVGSPPPAATPT-PTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPF 478
+ PPP A P TPP + P P A+ PG P AS P
Sbjct: 780 -----PLAKPPPQAPPALATPPLQALPS----PPASF---------PGQAPFSPSASLPM 821
Query: 479 LPGGGPA--TGPSVTNPF---QPAPPATLTLNQLRLSPVPPVPGAPPTYISP-----LGG 528
P P P + P P+PPA+ TL R PP PG + P L
Sbjct: 822 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR---PPTPGPDTSVSGPRLTLALAP 878
Query: 529 GPGLPPMMPP 538
GP PP P
Sbjct: 879 GPPPPPSRSP 888
Score = 62.0 bits (149), Expect = 1e-09
Identities = 96/347 (27%), Positives = 127/347 (36%), Gaps = 45/347 (12%)
Query: 240 TAPAPAP---TTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGG--PAPTPASGD 294
T A AP T P G P P P A G P A+ GG A P S
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
Query: 295 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPS-ASDPWTPAPAFSDP 353
P AG S P PA+G G P ++ G PVS P AS P P
Sbjct: 76 RAGPTRSAGTSSRNPASRP-PASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPL---- 129
Query: 354 WGGSPAKPSTNGTTAGGFDTEPDEFSDFD---RLRTALPTSGSSAGEL---ELLAGE--- 404
G + S T A G TE + S R T+ PT G+ + + AG
Sbjct: 130 -GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 405 VPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLG----PNAALVDLDS 460
+P +P A G ++V S +T P+P R+ P + G + +L +
Sbjct: 189 LPRPAPSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 461 LVSRPGPTPPGAKA--------SNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLS-- 510
+S P + P A+ S P G P VT P + A PA L+ L+
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 511 --------PVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFL 549
PVPP A + L P L +P PP+P+ P L
Sbjct: 308 SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354
Score = 61.2 bits (147), Expect = 2e-09
Identities = 82/323 (25%), Positives = 110/323 (34%), Gaps = 40/323 (12%)
Query: 242 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGP--APTPASGDPWRPA 299
PA P + P P P+A P+A P+ P PPA P P TP P P+
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTL---PSPPATPPSQAPPSMTTPPMQAP--PS 382
Query: 300 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDP---WTPAPAFSDPWGG 356
P + +P+ P+P S + P+ T +P +
Sbjct: 383 LQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLT 442
Query: 357 SPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMS 416
SP++P++ T PD L+ L S + L P SP
Sbjct: 443 SPSRPAS---------TPPDS----PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
Query: 417 GVRGSLAEAVGSPPPAATPTPTPPTRKT--PESFLGPNAALVDLDSLVSRPGPTPPGAKA 474
SLA P ++ P T+ + P S P A+L L + P PP
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLT-TPPLENLPSLAPP---- 544
Query: 475 SNPFLPGGGPATGPSVTNPFQPAP--------PATLTLNQLRLSPVPPVPGAPPTYISPL 526
P P T P + P PAP P T + S P P APP SP
Sbjct: 545 --PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602
Query: 527 GGGPGLPPMMPPGPPAPNTNPFL 549
G PP+ P P P P L
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXL 625
Score = 58.2 bits (139), Expect = 2e-08
Identities = 81/308 (26%), Positives = 111/308 (36%), Gaps = 39/308 (12%)
Query: 241 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWR--P 298
+P +P+ P P AA P P S P PP+ P+A P AP P + P + P
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPP-ASPPMSPSATP-PPQAPPPLAAPPLQVPP 739
Query: 299 AAPAGPSVDPWGGTPA---PAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWG 355
+ PA P + P P P P P S +P+S P A P PA + P
Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVP-PSPPASLPMS-PLAKPPPQAPPALATP-- 795
Query: 356 GSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA--- 412
A PS + G P L T P + L P SP
Sbjct: 796 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 855
Query: 413 ---------FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVS 463
+SG R +LA A G PPP P+ +P + + G +++ +
Sbjct: 856 RRPPTPGPDTSVSGPRLTLALAPGPPPP---PSRSPSSTLSGPDLAGHSSSATSTPEELR 912
Query: 464 RPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYI 523
P G A++P A P+ + PAPP R +P P+P P T
Sbjct: 913 GYDSGPEGGAAASPPPDAELAACHPAAWSR-GPAPPLA-----FRGAPGAPLPWPPAT-- 964
Query: 524 SPLGGGPG 531
GPG
Sbjct: 965 -----GPG 967
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/299 (26%), Positives = 103/299 (34%), Gaps = 48/299 (16%)
Query: 242 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAP 301
P+P P + P P +A++P + + P PPV A P+P PAS P P
Sbjct: 801 PSP-PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP-PASPTLQAPRRP 858
Query: 302 AGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKP 361
P D P P P P S +SGP D G S +
Sbjct: 859 PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP-------------DLAGHSSSAT 905
Query: 362 STNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAG---ELELLAGEVPARSPGAFDMSGV 418
ST P+E +D + P G++A + EL A A S G
Sbjct: 906 ST-----------PEELRGYD----SGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 950
Query: 419 RGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPF 478
RG A P P AT + T GP +A +L P P G KA+
Sbjct: 951 RG--APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA--- 1005
Query: 479 LPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP------VPGAPPTYISPLGGGPG 531
G G S +P Q A L L L+ S V + A GGGPG
Sbjct: 1006 ---AGAGAGASSRSPKQ-ARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG 1060
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 68.9 bits (167), Expect = 1e-11
Identities = 91/321 (28%), Positives = 113/321 (35%), Gaps = 56/321 (17%)
Query: 243 APAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA-- 300
+PA P P AAAVPT + P P P +P A P +P PAA
Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP--EEPTSPAAAVPTPEEPTSPAAAV 1085
Query: 301 -----PAGPSVD-PWGGTPAPAAGEGPTPDPWGSSDGGVPV----SGPSASDPWTPAPAF 350
P P+ P P A PTP+ S VP + P+A+ P PAF
Sbjct: 1086 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAF 1145
Query: 351 SDPWGGSPAK----------PSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELEL 400
P +P + P + + A T P E + F + L S A +
Sbjct: 1146 PAPAVPTPEESASAAVAVPTPEESASPAAAVPT-PAESASFAAVVATLEEPTSPAASVPT 1204
Query: 401 LAGEVPA----RSPGA-FDMSGVRGSLAEAVGSP-----PPAATPTPTPPTRK-----TP 445
A V SP A S SLA AV +P P AA PT PT TP
Sbjct: 1205 PAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP 1264
Query: 446 ESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLN 505
E P A S+ + P P A SN P A P+ P A PA
Sbjct: 1265 EELSSPAA------SVPTPEEPASPAAAVSNLEEPASPAAAVPT---PEVAAIPAASV-- 1313
Query: 506 QLRLSPVPPVPGAPPTYISPL 526
P P VP P + P+
Sbjct: 1314 -----PTPEVPAIPAAAVPPM 1329
Score = 62.8 bits (151), Expect = 8e-10
Identities = 94/325 (28%), Positives = 120/325 (36%), Gaps = 53/325 (16%)
Query: 243 APAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA-- 300
A PT + P AAAVPT + P VPP +P A P +P PAA
Sbjct: 1005 AAVPTPEE---PTSPAAAVPTPEEPTSP--AAAVPPPEEPTSPAAAVPTPEEPTSPAAAV 1059
Query: 301 -----PAGPSVD-PWGGTPAPAAGEGPTPDPWGSSDGGVPV----SGPSASDPWTP---- 346
P P+ P P A PTP+ S VP + P+A+ P TP
Sbjct: 1060 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP-TPEEPA 1118
Query: 347 APAFSDPWGGSPAKPSTNGTT-------AGGFDTEPDEFSDFDRLRTALPTSGSSAGELE 399
+PA + P PA P+ T A T + S A+PT SA
Sbjct: 1119 SPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESAS----AAVAVPTPEESASP-- 1172
Query: 400 LLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLD 459
A VP + A + V +L E + P A+ PTP T E F P A
Sbjct: 1173 --AAAVPTPAESA-SFAAVVATLEEP--TSPAASVPTPAAMV-ATLEEFTSPAA------ 1220
Query: 460 SLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLS----PVPPV 515
S+ + P A SNP P A P++ P A A LT +L P P
Sbjct: 1221 SVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSA-AAVLTPEELSSPAASVPTPEE 1279
Query: 516 PGAPPTYISPLGGGPGLPPMMPPGP 540
P +P +S L P P P P
Sbjct: 1280 PASPAAAVSNL-EEPASPAAAVPTP 1303
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 68.6 bits (166), Expect = 1e-11
Identities = 142/576 (24%), Positives = 201/576 (34%), Gaps = 116/576 (20%)
Query: 26 EATSNDPWGPSSSLMSEIADLTYNVVA--FSEIMSMIWKRLNDHGKNWRHVYKAMTLMEY 83
EA S + P S +E+A + N + E M K L +HG+NW + + +
Sbjct: 589 EANSEEAITPQQS--AELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMV----- 641
Query: 84 LIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREE 143
GS+ VSQ CK N Y F Y R D+ + + +L+ E
Sbjct: 642 ----GSKTVSQ-CK-NFY-------FNYKKRQNLDE--------------ILQQHKLKME 674
Query: 144 RAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS--SGEEELQLQLALAMSKEEADQ 201
+ + K+K A A + AA PP ++ S SG EE ++ A A +D
Sbjct: 675 KERNARRKKKKAPAAASEEAAF---PPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDT 731
Query: 202 EERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAV 261
E + E+ ++TG L P P PT P PAP
Sbjct: 732 ES---------IPSPHTEAAKDTGQNGPKPPATLGADGPPPGP-PTPPPEDIPAPTE--- 778
Query: 262 PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGE-- 319
PT P S+ G P PPA P P + A A P V+ PAA E
Sbjct: 779 PT--PASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETA-AAPPVEEGEEQKPPAAEELA 835
Query: 320 ---GPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSD-------PWGGS----------PA 359
G +P S GP+ A A ++ GGS
Sbjct: 836 VDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAP 895
Query: 360 KPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGE----------LELLAGEVPARS 409
+ S + T + + E D +RL + P+ + G+ L+L + A +
Sbjct: 896 QDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAA 955
Query: 410 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 469
++ V E +P A P P PP PES S P P
Sbjct: 956 IPPIQVTKVHEPPREDA-APTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRS---PAP 1011
Query: 470 PGAK-ASNPF-----------LPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPG 517
P K A P LPG P + PF P PP + ++ SP P P
Sbjct: 1012 PADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGL--PF-PVPPREV----IKASPHAPDPS 1064
Query: 518 A----PPTYISPLGGGPGLPPMMPPGPPAPNTNPFL 549
A PP + PLG P++P P N P +
Sbjct: 1065 AFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLI 1100
Score = 33.1 bits (74), Expect = 0.68
Identities = 83/357 (23%), Positives = 113/357 (31%), Gaps = 68/357 (19%)
Query: 151 KEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDD 210
+EK +TA A G P A + +G+ E ++ EE + + +
Sbjct: 808 EEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAE 867
Query: 211 LRLQMAIEESKRETGG-------------KEESSLMDLADV-----------FTAPAPA- 245
+ A++ K+E G +SS AD +P P+
Sbjct: 868 ATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSL 927
Query: 246 --PTTDPWGGPAPM-----------AAAVPT-------------AAPTSDPWGGPPVPPA 279
PT DP +P AAA+P AAPT PP P
Sbjct: 928 LTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQN 987
Query: 280 ADPWGGPAPTPAS---GDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS 336
P P S G PA PA + PA AA P G+P
Sbjct: 988 LQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFP 1047
Query: 337 GPS----ASDPWTPAP-AFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTS 391
P + P P P AFS G P P TA P S+ P
Sbjct: 1048 VPPREVIKASPHAPDPSAFSYAPPGHPL-PLGLHDTARPVLPRPPTISN-------PPPL 1099
Query: 392 GSSAGELELLAGEVPARSPG-AFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPES 447
SSA +L ++ A S G + + A+A P P P P + P S
Sbjct: 1100 ISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFS 1156
Score = 32.0 bits (71), Expect = 1.5
Identities = 49/191 (25%), Positives = 63/191 (32%), Gaps = 34/191 (17%)
Query: 343 PWTPAPAFSDPWGGSPAKPS-----TNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGE 397
P P P FS SP P T TT + E D + DR R + +S
Sbjct: 1753 PTAPQP-FSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTT 1811
Query: 398 LELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVD 457
+E P PG SG GS GS + P + S + P
Sbjct: 1812 VE----HAPIWRPGTEQSSGSSGSSGGGGGS-----SSRPASHSHAHQHSPISPRTQ--- 1859
Query: 458 LDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPG 517
D+L RP + N + G + +P+ P L SPV P
Sbjct: 1860 -DALQQRP------SVLHNTGMKG--------IITAVEPSTPTVLRSTSTS-SPVRPAAT 1903
Query: 518 APPTYISPLGG 528
PP PLGG
Sbjct: 1904 FPPATHCPLGG 1914
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 68.6 bits (166), Expect = 1e-11
Identities = 110/422 (26%), Positives = 144/422 (34%), Gaps = 79/422 (18%)
Query: 170 PPEAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEE 229
P + ++AW Q + ++ LA+ ++ ++EER R + R E+ KR
Sbjct: 442 PEDEDEAWRQRRKQSSSEISLAVERARRRREEEER--RMQEERRAACAEKLKR------- 492
Query: 230 SSLMDLADVFTAPAPAPTTDPWGGP-APMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAP 288
L + F AP +P P AP A P A P P PP PP A AP
Sbjct: 493 -----LDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELP--APPAPPPAS-----AP 540
Query: 289 TPASGDPWRPA-APAGPSVDPWGGTPAP--AAGEGPTPDPWGSSDGGVPVSGPSASDPWT 345
TP + +P PA AP S G AP +G G T S PV P
Sbjct: 541 TPET-EPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVE-PQLPSKEG 598
Query: 346 PAPAFSDPWGGSPAKPST--NGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 403
P P P +P P G G P + + + + +LP + +LL
Sbjct: 599 PEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQ 658
Query: 404 E-----------------VPARSPGAFDMSGVRGSLAEAVGSPPPAA-------TPTPTP 439
+ VP P + V A PPP A P P P
Sbjct: 659 QQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVP---APQAPPPPPKALYPGALGRPPPMP 715
Query: 440 PTRKTPESFLGPNAALVDLDSLVSRPGPT--PPGAKASNPFLPGGGPATGPSVTNPFQPA 497
P P + P VD L RP PPG S +P +G S + PF
Sbjct: 716 PMNFDPRWMMIP--PYVDPRLLQGRPPLDFYPPGVHPSG-LVPRERSDSGGSSSEPFDRH 772
Query: 498 PPATLTLNQLRLSPVPP-----------VPGAPPTYISPL-----GGGPGLPPMMPPGPP 541
PA L + PV P P P SPL G+ PP PP
Sbjct: 773 APA--MLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPP 830
Query: 542 AP 543
P
Sbjct: 831 PP 832
Score = 68.2 bits (165), Expect = 2e-11
Identities = 101/429 (23%), Positives = 142/429 (33%), Gaps = 95/429 (22%)
Query: 172 EAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESS 231
E + W + E + +L + ++ D +E G + EE E GK+ +S
Sbjct: 321 ENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNS 380
Query: 232 LMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGP-PVPPAADP-------W 283
P ++P P P A T+ P G P P PP P W
Sbjct: 381 --------------PNSEP---PTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNW 423
Query: 284 GGPAPTP-ASGDPWRPAAPAGPSVDPWGGTPAPAAGE----------------------- 319
G P P G P +P AP + W ++ E
Sbjct: 424 GPPGDYPDRGGPPCKPPAPEDED-EAWRQRRKQSSSEISLAVERARRRREEEERRMQEER 482
Query: 320 --------GPTPDPWGSSDGGV---PVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTA 368
+ +G+ D + P + P+A P PA PA P + T
Sbjct: 483 RAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTP 542
Query: 369 GGFDTEPDEFSDFDRLRTALPTSG-SSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVG 427
+TEP+E + ++ PT G ++A L G + S G+F+ S V L G
Sbjct: 543 ---ETEPEEPAQAPPAQST-PTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEG 598
Query: 428 SPPPAATPTPTP--------------PTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAK 473
PP P PT PTR+ P LG L R +
Sbjct: 599 PEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQ 658
Query: 474 AS----NPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGG 529
G P T P P+PP +TL + P P P PP + P G
Sbjct: 659 QQQHQWQQHQQGSAPPT------PVPPSPPQPVTLGAV---PAPQAPPPPPKALYP--GA 707
Query: 530 PGLPPMMPP 538
G PP MPP
Sbjct: 708 LGRPPPMPP 716
Score = 42.0 bits (97), Expect = 0.001
Identities = 78/304 (25%), Positives = 107/304 (35%), Gaps = 63/304 (20%)
Query: 265 APTSDPWGGPPVPPAADPWGGPAPTPASG-DPWRPAA---------PAGPSVDPWGGTPA 314
AP P P +P A GP+P P + +P R + GP V GGTP
Sbjct: 1492 APGGHPRHKPGLPQAPQ---GPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPR 1548
Query: 315 PAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTE 374
+AG P P P P + P S + GS KP G A DT
Sbjct: 1549 DSAGVSPFPPKRRER----PPRKPELLQEESLPPPHSSGFLGS--KPEGPGPQAESRDTG 1602
Query: 375 PDEFSD--FDRLRTALPTSGSSAGELEL----------LAGEVPARSPGAFDMSGVRGSL 422
+ + ++RL TA +E +AG ++S D+SG
Sbjct: 1603 TEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSG----- 1657
Query: 423 AEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGG 482
V S P + +P + E GP RPG + P
Sbjct: 1658 DSQVSSGPCSQRSSPDGGLKGAAE---GP----------PKRPGGSSP---------LNA 1695
Query: 483 GPATGPSVTNPFQPAPPATLTLNQLRL---SPVPPVP-GAPPTYISPLGGGPG-LPPMMP 537
P GP + P + PPA ++ L P+PP P G + + G PG + P
Sbjct: 1696 VPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHR 1755
Query: 538 PGPP 541
PGPP
Sbjct: 1756 PGPP 1759
Score = 40.4 bits (93), Expect = 0.004
Identities = 72/279 (25%), Positives = 87/279 (31%), Gaps = 52/279 (18%)
Query: 235 LADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGD 294
+ DVFTA P P P AA S+ PPVPP P P AS
Sbjct: 792 VGDVFTATPAEPR--PLTSPLRQAADEDDKGMRSET---PPVPP-------PPPYLASYP 839
Query: 295 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPW--GSSDGGVPVSGPSASDPWTPAPAFSD 352
+ GP + + P GP P PW GS + + P +P P +
Sbjct: 840 GFPENGAPGPPISRF-----PLEEPGPRPLPWPPGSDEVAKIQTPPPKKEP--PKEETAQ 892
Query: 353 PWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 412
G + G +GG P R P GSS
Sbjct: 893 LTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWG-PRPGSSR----------------- 934
Query: 413 FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGA 472
RG E G+PP A P PP E P L D P P P
Sbjct: 935 ------RGIPPEEPGAPPRRAGPIKKPPPPTKVEEL--PPKPLEQGDETPKPPKPDP--L 984
Query: 473 KASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSP 511
K + L GGP P N PAP + R+ P
Sbjct: 985 KITKGKL--GGPKETPPNGN-LSPAPRLRRDYSYERVGP 1020
Score = 39.7 bits (91), Expect = 0.007
Identities = 105/458 (22%), Positives = 148/458 (32%), Gaps = 80/458 (17%)
Query: 161 SSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEES 220
SS +GS P QA + +G E L + + + + R + ++ E
Sbjct: 1581 SSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFED 1640
Query: 221 KRETGGKEESSLMDLA---DVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPV- 276
T + S +DL+ V + P + + P GG A P S P P
Sbjct: 1641 VAGTEMSQSDSGVDLSGDSQVSSGPC-SQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCE 1699
Query: 277 -PPAADPWGGPAPTPASGD----PWRPAAPAGP-----------SVDPWGGTPAPAAGEG 320
PP ++P P P P GD P P GP +P G P+ G
Sbjct: 1700 GPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEP--GPIRPSHRPG 1757
Query: 321 PTPDPWGSSD---------GGVPVSGPSASDPWTPAPAFSDPW-----GGSPAKPSTNGT 366
P P +G+SD G + + T A S W + A+P +
Sbjct: 1758 P-PVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNL 1816
Query: 367 TAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR--------SPGAFDMSGV 418
+G EP S RL + + ++ G + ++ PG +
Sbjct: 1817 DSGHCVPEPS--SSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPY 1874
Query: 419 RGS-LAEAVGSPPPAATPT----------------------PTPPTRKTPESFLGPNA-- 453
R L G PP+A + P P SFL A
Sbjct: 1875 RSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFC 1934
Query: 454 --ALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT----LNQL 507
L D L R P S P PGG PS Q P + +N
Sbjct: 1935 PSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFG 1994
Query: 508 RLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 545
L P PP P PP + P+G P + PPAP T
Sbjct: 1995 SLPPAPP-PAPPPLSLLPVGPALQPPSLAVRPPPAPAT 2031
Score = 38.5 bits (88), Expect = 0.016
Identities = 81/340 (23%), Positives = 103/340 (30%), Gaps = 69/340 (20%)
Query: 244 PAPTTDPWGGPAPMAAAV-PTAAPTSDPWGGPPVPPAADP------------------W- 283
P PTT P P + PT P S G P + P W
Sbjct: 606 PPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQ 665
Query: 284 ----GGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPS 339
G PTP P +P G PAP A P + + G P P
Sbjct: 666 QHQQGSAPPTPVPPSPPQPVT--------LGAVPAPQAPPPPPKALYPGALGRPPPMPPM 717
Query: 340 ASDP-WTPAPAFSDP---WGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSA 395
DP W P + DP G P G G P E SD SG S+
Sbjct: 718 NFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGL--VPRERSD----------SGGSS 765
Query: 396 GELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAAL 455
E R G + + + + P P +P + E G +
Sbjct: 766 SEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSE- 824
Query: 456 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTN-PFQPAPPATLT----LNQLRLS 510
+ P P PP AS P P G A GP ++ P + P L +++
Sbjct: 825 -------TPPVPPPPPYLASYPGFPENG-APGPPISRFPLEEPGPRPLPWPPGSDEVAKI 876
Query: 511 PVPPVPGAPPTYISPLGGGP--GLPPMM-----PPGPPAP 543
PP PP + GP G P GPP P
Sbjct: 877 QTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPP 916
Score = 36.2 bits (82), Expect = 0.080
Identities = 95/367 (25%), Positives = 117/367 (31%), Gaps = 105/367 (28%)
Query: 220 SKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDP--------W 271
SK+E + S + P PA T PA P AAP + P W
Sbjct: 88 SKQEQSDPKSSDASTAQPPESQPLPASQT-----PASNQPKRPPAAPENTPLVPSGVKSW 142
Query: 272 GGPPVPPAADPWGGPA------------PT-PASGDPWRPA---------APAGPSVDP- 308
V A GG A PT A+GD + A + GPS+ P
Sbjct: 143 AQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQ 202
Query: 309 ----W--GGTPAPAAGEGPTPDPWGSSD--GGVPVSGPSASDPWT---------PAPAFS 351
W GG P EGP D GG+ SGP P+ P F
Sbjct: 203 NSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFP 262
Query: 352 DPWGG-------SPAKPSTNGTTAGGFDTEP----------------DEFSDFDRLRTAL 388
P+G +P PS AG + P D +FD+L
Sbjct: 263 PPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQEN 322
Query: 389 PTSGSSAGE----LELL--AGEVPARSPGAFDMSGVRGSLAEAVGSPPPAA------TPT 436
+ A E E L + E R G R S + + PP A +P
Sbjct: 323 DDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPN 382
Query: 437 PTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL--PGGGPA--TGPSVTN 492
PPT KT + SRP T PG A P L P GPA GP
Sbjct: 383 SEPPTPKTAWAE-------------TSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDY 429
Query: 493 PFQPAPP 499
P + PP
Sbjct: 430 PDRGGPP 436
Score = 33.9 bits (76), Expect = 0.40
Identities = 42/168 (25%), Positives = 62/168 (36%), Gaps = 20/168 (11%)
Query: 355 GGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPT-SGSSAGELELLAGEVPARSPGAF 413
GG P+ G TA +E E+ + + R + +GS E +L + A +P
Sbjct: 1071 GGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPK-- 1128
Query: 414 DMSGVRGSLAEA-VGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGA 472
G+L + + PPP A P+P P F + + SR G G
Sbjct: 1129 -----EGTLTQVPLAPPPPGAPPSP------APARFTARGGRVFTPRGVPSRRG--RGGG 1175
Query: 473 KASNPFLPGGGPATGPSVTN--PFQPAPPATLTLNQLRLSPVPPVPGA 518
+ PG P P P PP+ L + +L P P P A
Sbjct: 1176 RPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKE-KLIPGPLSPVA 1222
Score = 33.1 bits (74), Expect = 0.68
Identities = 54/220 (24%), Positives = 73/220 (33%), Gaps = 20/220 (9%)
Query: 336 SGPSASDPWTPAPAFSDPWGGS--PAKPSTNGTTAGGFDTE--PDEFSDFDRLRTALPTS 391
S P +SD T P S P S PA A +T P + +
Sbjct: 93 SDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAH 152
Query: 392 GSSAGELELLAG----EVPA-RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTR---- 442
G LL+ E P ++ G D + AE P P+ P + R
Sbjct: 153 GDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGG 212
Query: 443 KTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATL 502
+ P+ GP++ L R G P G P+ P P P+ P PP
Sbjct: 213 RGPDELEGPDSKLHHGHD--PRGGLQPSGPPQFPPYRGMMPPFMYP----PYLPFPPPYG 266
Query: 503 TLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPA 542
R P P P P P G GP + + P G P+
Sbjct: 267 PQGPYRY-PTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPS 305
Score = 31.6 bits (70), Expect = 2.0
Identities = 79/355 (22%), Positives = 122/355 (34%), Gaps = 53/355 (14%)
Query: 198 EADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPM 257
+ D + R+ GD L+ + + S E ++ D P+ A + +P
Sbjct: 1766 DKDSDLRLVVGDSLKAEKELTASVTE-------AIPVSRDWELLPSAAASAEPQSKNLDS 1818
Query: 258 AAAVPTAAPTS-----DPWGGPPVPPAADPWGGPAPT---PASGDPWRPAAPAGPSVDPW 309
VP + + + + G P ++ GG + P SG P PS+ P+
Sbjct: 1819 GHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGG----FRPGTPSLHPY 1874
Query: 310 GGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAG 369
P P P P + G+ + G A G P + +
Sbjct: 1875 RSQPLYLP---PGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSP 1931
Query: 370 GFDTEPDEFSDFDRLRTALPTSG---SSAGELELLAGEVPARSPGAFDMSGVRGSLAEAV 426
F P + ++R LP+ S+ + +G +P+ +P + + S V
Sbjct: 1932 AFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVV 1991
Query: 427 --GSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGP 484
GS PPA P P PP P +GP + SL RP P P + LP
Sbjct: 1992 NFGSLPPAPPPAP-PPLSLLP---VGP---ALQPPSLAVRPPPAP-----ATRVLPS--- 2036
Query: 485 ATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG 539
PA P +L + L PV P +S GGPG P G
Sbjct: 2037 -----------PARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTG 2080
Score = 30.0 bits (66), Expect = 5.7
Identities = 71/268 (26%), Positives = 90/268 (33%), Gaps = 48/268 (17%)
Query: 287 APTPASGDPWR-PAAPAGPSVDPWGGTPAPA---AGEGPTPDPWG-----SSDGGVPVSG 337
APTP G + P AP P P +PAPA A G P G GG P
Sbjct: 1124 APTPKEGTLTQVPLAPPPPGAPP---SPAPARFTARGGRVFTPRGVPSRRGRGGGRPP-- 1178
Query: 338 PSASDPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGE 397
P W+P PA S +P KP T EP + + + GS+ G
Sbjct: 1179 PQVCPGWSP-PAKSL----APKKPPTGPLPPS---KEPLKEKLIPGPLSPVARGGSNGGS 1230
Query: 398 -LELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPP----------AATPTPTPPTRKTPE 446
+ + GE P R R A+ PP AA + P+ P
Sbjct: 1231 NVGMEDGERPRRR---------RHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPA 1281
Query: 447 SFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQ 506
S GP AL + P P A A +P L + T
Sbjct: 1282 SAPGPEEALTTVTV-----APAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRG 1336
Query: 507 LRLSPVPPVPGAPPTYISPLGGGPGLPP 534
+ +P PPV P +P GGG G P
Sbjct: 1337 DKEAP-PPVLLTPKAVGTPGGGGGGAVP 1363
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 68.6 bits (166), Expect = 1e-11
Identities = 97/355 (27%), Positives = 122/355 (34%), Gaps = 68/355 (19%)
Query: 227 KEESSLMDLADVFTAPAPAPTTDPWGGPA--PMAAAVPTAAPTSDPWGGPPVPPAADPWG 284
KE SLM A++ AP PA + GPA P+A+A AAP ++P PP+
Sbjct: 311 KEYLSLM--AELGEAPVPA-SVGSTSGPATTPLASAPRPAAPANNP-----PPPSL---- 358
Query: 285 GPAPTPASGDPWRPAAPAG--PSVDPWGGTPA-PAAGEGPTPDPWGSSDGGVPVSGPSAS 341
T S PW + P+ P GG P P G P P S GG P
Sbjct: 359 --MSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHG-GHPMQH 415
Query: 342 DPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELL 401
+P P P PW P P G G P D+ + P GS L
Sbjct: 416 NPNGPPP----PWMQPPPPPMNQGPHPPGHHGPPP----MDQYLGSTPV-GSGVYRLHQG 466
Query: 402 AGEVPARSPGAFDMSGVRGSLAEAVGSPPPAAT-------------PTPTPPTRKTPESF 448
G +P G S G PPP + P P PP+ S
Sbjct: 467 KGMMPPPPMGMMPPPPPPPS-----GQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASST 521
Query: 449 LGPNAALVDLDSLVSRPGPTPP------------------GAKASNPFLPGGGPATGPSV 490
P + + G PP G P PG P P
Sbjct: 522 PLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGA 581
Query: 491 TNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLG-GGPGLPPM-MPPGPPAP 543
P P PP + + P PP P P +++ +G G G+PP MPP PP P
Sbjct: 582 PPPPPPPPPGSAGM-MYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPP 635
Score = 31.6 bits (70), Expect = 2.0
Identities = 28/93 (30%), Positives = 31/93 (33%), Gaps = 13/93 (13%)
Query: 241 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPP-----AADPWGGPAPTPASGDP 295
A A +P G M P P P PP PP A + P P P DP
Sbjct: 550 AAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDP 609
Query: 296 WRPAAPAGPSV---DPWGGTPAPAAGEGPTPDP 325
G V P+G PAP P P P
Sbjct: 610 SNFVTMMGMGVAGMPPFGMPPAP-----PPPPP 637
>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform A [Homo sapiens]
Length = 1679
Score = 68.2 bits (165), Expect = 2e-11
Identities = 89/345 (25%), Positives = 110/345 (31%), Gaps = 66/345 (19%)
Query: 242 PAPAPTTDPWGGPAPMAAAVPTAAPTS--DPWGGPPVPPAADPWGGPAPTPASG------ 293
P P P+ P P M P +P S G P PP+A G P PT G
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA---GHPIPTQGPGGYPQDN 68
Query: 294 -----DPWRPAAPAGPSVDP-------WGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSAS 341
P G S DP G AG GP P P G P +
Sbjct: 69 MHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128
Query: 342 DPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELL 401
+P PA S P G G G D P +R T + +++
Sbjct: 129 HASSPVPA-SGPSSGPQMSSGPGGAPLDGAD--PQALGQQNRGPTPFNQNQLHQLRAQIM 185
Query: 402 AGEVPARS-----------PGAFDMSGVRGSL-------AEAVG-----SPPPAATPTPT 438
A ++ AR G M G++ + A G P P P P
Sbjct: 186 AYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPA 245
Query: 439 PPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAP 498
PP P GPN P P P G P P GGP P P A
Sbjct: 246 PPNYSRPHGMGGPN-----------MPPPGPSGVPPGMPGQPPGGPPK-PWPEGPMANAA 293
Query: 499 PATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 543
T T +L +PP P P+ +P P P+MPP +P
Sbjct: 294 APTSTPQKL----IPPQPTGRPS-PAPPAVPPAASPVMPPQTQSP 333
Score = 55.1 bits (131), Expect = 2e-07
Identities = 80/283 (28%), Positives = 100/283 (35%), Gaps = 33/283 (11%)
Query: 275 PVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVP 334
P PP G P P P+ G P A GPS P G+ G P P S+ +P
Sbjct: 4 PDPPLG---GTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPP---SAGHPIP 57
Query: 335 VSGPSA----SDPWTPAPAFSDPWGGSPAKPSTN-----GTTAGGFDTEPDEFSDFDRLR 385
GP + P S G P N G +GG S D+
Sbjct: 58 TQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHS 117
Query: 386 TALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTP 445
P S G E + VPA P SG + S G+P A P + P
Sbjct: 118 QGYP---SPLGGSEHASSPVPASGPS----SGPQMSSGPG-GAPLDGADPQALGQQNRGP 169
Query: 446 ESF----LGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT 501
F L A + +++R P P + + + G P G P P P +
Sbjct: 170 TPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMA---VQGKRPMPGMQQQMPTLPPPSVS 226
Query: 502 LTLNQLRLSPVP-PVPG-APPTYISPLG-GGPGLPPMMPPGPP 541
T P P P PG APP Y P G GGP +PP P G P
Sbjct: 227 ATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVP 269
Score = 49.3 bits (116), Expect = 9e-06
Identities = 50/171 (29%), Positives = 64/171 (37%), Gaps = 33/171 (19%)
Query: 205 IRRGDDL--RLQMAIEESKRETGGKEESSLMDLADVF-TAPAPAPTTDPWGGPAPMAAAV 261
+ RG L LQMA++ + G +++ + V T P P P P GP P
Sbjct: 190 LARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGP----A 245
Query: 262 PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPW-GGTPAPAAGEG 320
P GGP +PP P P+ P P P G PW G A AA
Sbjct: 246 PPNYSRPHGMGGPNMPP---------PGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPT 296
Query: 321 PT------PDPWGSSDGGVPVSGPSAS---DPWTPAPAFSDPWGGSPAKPS 362
T P P G P P+AS P T +P G PA+P+
Sbjct: 297 STPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSP-------GQPAQPA 340
>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform F [Homo sapiens]
Length = 1613
Score = 68.2 bits (165), Expect = 2e-11
Identities = 89/345 (25%), Positives = 110/345 (31%), Gaps = 66/345 (19%)
Query: 242 PAPAPTTDPWGGPAPMAAAVPTAAPTS--DPWGGPPVPPAADPWGGPAPTPASG------ 293
P P P+ P P M P +P S G P PP+A G P PT G
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA---GHPIPTQGPGGYPQDN 68
Query: 294 -----DPWRPAAPAGPSVDP-------WGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSAS 341
P G S DP G AG GP P P G P +
Sbjct: 69 MHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128
Query: 342 DPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELL 401
+P PA S P G G G D P +R T + +++
Sbjct: 129 HASSPVPA-SGPSSGPQMSSGPGGAPLDGAD--PQALGQQNRGPTPFNQNQLHQLRAQIM 185
Query: 402 AGEVPARS-----------PGAFDMSGVRGSL-------AEAVG-----SPPPAATPTPT 438
A ++ AR G M G++ + A G P P P P
Sbjct: 186 AYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPA 245
Query: 439 PPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAP 498
PP P GPN P P P G P P GGP P P A
Sbjct: 246 PPNYSRPHGMGGPN-----------MPPPGPSGVPPGMPGQPPGGPPK-PWPEGPMANAA 293
Query: 499 PATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 543
T T +L +PP P P+ +P P P+MPP +P
Sbjct: 294 APTSTPQKL----IPPQPTGRPS-PAPPAVPPAASPVMPPQTQSP 333
Score = 55.1 bits (131), Expect = 2e-07
Identities = 80/283 (28%), Positives = 100/283 (35%), Gaps = 33/283 (11%)
Query: 275 PVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVP 334
P PP G P P P+ G P A GPS P G+ G P P S+ +P
Sbjct: 4 PDPPLG---GTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPP---SAGHPIP 57
Query: 335 VSGPSA----SDPWTPAPAFSDPWGGSPAKPSTN-----GTTAGGFDTEPDEFSDFDRLR 385
GP + P S G P N G +GG S D+
Sbjct: 58 TQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHS 117
Query: 386 TALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTP 445
P S G E + VPA P SG + S G+P A P + P
Sbjct: 118 QGYP---SPLGGSEHASSPVPASGPS----SGPQMSSGPG-GAPLDGADPQALGQQNRGP 169
Query: 446 ESF----LGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT 501
F L A + +++R P P + + + G P G P P P +
Sbjct: 170 TPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMA---VQGKRPMPGMQQQMPTLPPPSVS 226
Query: 502 LTLNQLRLSPVP-PVPG-APPTYISPLG-GGPGLPPMMPPGPP 541
T P P P PG APP Y P G GGP +PP P G P
Sbjct: 227 ATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVP 269
Score = 49.3 bits (116), Expect = 9e-06
Identities = 50/171 (29%), Positives = 64/171 (37%), Gaps = 33/171 (19%)
Query: 205 IRRGDDL--RLQMAIEESKRETGGKEESSLMDLADVF-TAPAPAPTTDPWGGPAPMAAAV 261
+ RG L LQMA++ + G +++ + V T P P P P GP P
Sbjct: 190 LARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGP----A 245
Query: 262 PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPW-GGTPAPAAGEG 320
P GGP +PP P P+ P P P G PW G A AA
Sbjct: 246 PPNYSRPHGMGGPNMPP---------PGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPT 296
Query: 321 PT------PDPWGSSDGGVPVSGPSAS---DPWTPAPAFSDPWGGSPAKPS 362
T P P G P P+AS P T +P G PA+P+
Sbjct: 297 STPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSP-------GQPAQPA 340
>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform E [Homo sapiens]
Length = 1614
Score = 68.2 bits (165), Expect = 2e-11
Identities = 89/345 (25%), Positives = 110/345 (31%), Gaps = 66/345 (19%)
Query: 242 PAPAPTTDPWGGPAPMAAAVPTAAPTS--DPWGGPPVPPAADPWGGPAPTPASG------ 293
P P P+ P P M P +P S G P PP+A G P PT G
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA---GHPIPTQGPGGYPQDN 68
Query: 294 -----DPWRPAAPAGPSVDP-------WGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSAS 341
P G S DP G AG GP P P G P +
Sbjct: 69 MHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128
Query: 342 DPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELL 401
+P PA S P G G G D P +R T + +++
Sbjct: 129 HASSPVPA-SGPSSGPQMSSGPGGAPLDGAD--PQALGQQNRGPTPFNQNQLHQLRAQIM 185
Query: 402 AGEVPARS-----------PGAFDMSGVRGSL-------AEAVG-----SPPPAATPTPT 438
A ++ AR G M G++ + A G P P P P
Sbjct: 186 AYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPA 245
Query: 439 PPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAP 498
PP P GPN P P P G P P GGP P P A
Sbjct: 246 PPNYSRPHGMGGPN-----------MPPPGPSGVPPGMPGQPPGGPPK-PWPEGPMANAA 293
Query: 499 PATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 543
T T +L +PP P P+ +P P P+MPP +P
Sbjct: 294 APTSTPQKL----IPPQPTGRPS-PAPPAVPPAASPVMPPQTQSP 333
Score = 55.1 bits (131), Expect = 2e-07
Identities = 80/283 (28%), Positives = 100/283 (35%), Gaps = 33/283 (11%)
Query: 275 PVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVP 334
P PP G P P P+ G P A GPS P G+ G P P S+ +P
Sbjct: 4 PDPPLG---GTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPP---SAGHPIP 57
Query: 335 VSGPSA----SDPWTPAPAFSDPWGGSPAKPSTN-----GTTAGGFDTEPDEFSDFDRLR 385
GP + P S G P N G +GG S D+
Sbjct: 58 TQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHS 117
Query: 386 TALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTP 445
P S G E + VPA P SG + S G+P A P + P
Sbjct: 118 QGYP---SPLGGSEHASSPVPASGPS----SGPQMSSGPG-GAPLDGADPQALGQQNRGP 169
Query: 446 ESF----LGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT 501
F L A + +++R P P + + + G P G P P P +
Sbjct: 170 TPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMA---VQGKRPMPGMQQQMPTLPPPSVS 226
Query: 502 LTLNQLRLSPVP-PVPG-APPTYISPLG-GGPGLPPMMPPGPP 541
T P P P PG APP Y P G GGP +PP P G P
Sbjct: 227 ATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVP 269
Score = 49.3 bits (116), Expect = 9e-06
Identities = 50/171 (29%), Positives = 64/171 (37%), Gaps = 33/171 (19%)
Query: 205 IRRGDDL--RLQMAIEESKRETGGKEESSLMDLADVF-TAPAPAPTTDPWGGPAPMAAAV 261
+ RG L LQMA++ + G +++ + V T P P P P GP P
Sbjct: 190 LARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGP----A 245
Query: 262 PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPW-GGTPAPAAGEG 320
P GGP +PP P P+ P P P G PW G A AA
Sbjct: 246 PPNYSRPHGMGGPNMPP---------PGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPT 296
Query: 321 PT------PDPWGSSDGGVPVSGPSAS---DPWTPAPAFSDPWGGSPAKPS 362
T P P G P P+AS P T +P G PA+P+
Sbjct: 297 STPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSP-------GQPAQPA 340
>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform D [Homo sapiens]
Length = 1616
Score = 68.2 bits (165), Expect = 2e-11
Identities = 89/345 (25%), Positives = 110/345 (31%), Gaps = 66/345 (19%)
Query: 242 PAPAPTTDPWGGPAPMAAAVPTAAPTS--DPWGGPPVPPAADPWGGPAPTPASG------ 293
P P P+ P P M P +P S G P PP+A G P PT G
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA---GHPIPTQGPGGYPQDN 68
Query: 294 -----DPWRPAAPAGPSVDP-------WGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSAS 341
P G S DP G AG GP P P G P +
Sbjct: 69 MHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128
Query: 342 DPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELL 401
+P PA S P G G G D P +R T + +++
Sbjct: 129 HASSPVPA-SGPSSGPQMSSGPGGAPLDGAD--PQALGQQNRGPTPFNQNQLHQLRAQIM 185
Query: 402 AGEVPARS-----------PGAFDMSGVRGSL-------AEAVG-----SPPPAATPTPT 438
A ++ AR G M G++ + A G P P P P
Sbjct: 186 AYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPA 245
Query: 439 PPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAP 498
PP P GPN P P P G P P GGP P P A
Sbjct: 246 PPNYSRPHGMGGPN-----------MPPPGPSGVPPGMPGQPPGGPPK-PWPEGPMANAA 293
Query: 499 PATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 543
T T +L +PP P P+ +P P P+MPP +P
Sbjct: 294 APTSTPQKL----IPPQPTGRPS-PAPPAVPPAASPVMPPQTQSP 333
Score = 55.1 bits (131), Expect = 2e-07
Identities = 80/283 (28%), Positives = 100/283 (35%), Gaps = 33/283 (11%)
Query: 275 PVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVP 334
P PP G P P P+ G P A GPS P G+ G P P S+ +P
Sbjct: 4 PDPPLG---GTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPP---SAGHPIP 57
Query: 335 VSGPSA----SDPWTPAPAFSDPWGGSPAKPSTN-----GTTAGGFDTEPDEFSDFDRLR 385
GP + P S G P N G +GG S D+
Sbjct: 58 TQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHS 117
Query: 386 TALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTP 445
P S G E + VPA P SG + S G+P A P + P
Sbjct: 118 QGYP---SPLGGSEHASSPVPASGPS----SGPQMSSGPG-GAPLDGADPQALGQQNRGP 169
Query: 446 ESF----LGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT 501
F L A + +++R P P + + + G P G P P P +
Sbjct: 170 TPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMA---VQGKRPMPGMQQQMPTLPPPSVS 226
Query: 502 LTLNQLRLSPVP-PVPG-APPTYISPLG-GGPGLPPMMPPGPP 541
T P P P PG APP Y P G GGP +PP P G P
Sbjct: 227 ATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVP 269
Score = 49.3 bits (116), Expect = 9e-06
Identities = 50/171 (29%), Positives = 64/171 (37%), Gaps = 33/171 (19%)
Query: 205 IRRGDDL--RLQMAIEESKRETGGKEESSLMDLADVF-TAPAPAPTTDPWGGPAPMAAAV 261
+ RG L LQMA++ + G +++ + V T P P P P GP P
Sbjct: 190 LARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGP----A 245
Query: 262 PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPW-GGTPAPAAGEG 320
P GGP +PP P P+ P P P G PW G A AA
Sbjct: 246 PPNYSRPHGMGGPNMPP---------PGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPT 296
Query: 321 PT------PDPWGSSDGGVPVSGPSAS---DPWTPAPAFSDPWGGSPAKPS 362
T P P G P P+AS P T +P G PA+P+
Sbjct: 297 STPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSP-------GQPAQPA 340
>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform C [Homo sapiens]
Length = 1617
Score = 68.2 bits (165), Expect = 2e-11
Identities = 89/345 (25%), Positives = 110/345 (31%), Gaps = 66/345 (19%)
Query: 242 PAPAPTTDPWGGPAPMAAAVPTAAPTS--DPWGGPPVPPAADPWGGPAPTPASG------ 293
P P P+ P P M P +P S G P PP+A G P PT G
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA---GHPIPTQGPGGYPQDN 68
Query: 294 -----DPWRPAAPAGPSVDP-------WGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSAS 341
P G S DP G AG GP P P G P +
Sbjct: 69 MHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128
Query: 342 DPWTPAPAFSDPWGGSPAKPSTNGTTAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELL 401
+P PA S P G G G D P +R T + +++
Sbjct: 129 HASSPVPA-SGPSSGPQMSSGPGGAPLDGAD--PQALGQQNRGPTPFNQNQLHQLRAQIM 185
Query: 402 AGEVPARS-----------PGAFDMSGVRGSL-------AEAVG-----SPPPAATPTPT 438
A ++ AR G M G++ + A G P P P P
Sbjct: 186 AYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPA 245
Query: 439 PPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAP 498
PP P GPN P P P G P P GGP P P A
Sbjct: 246 PPNYSRPHGMGGPN-----------MPPPGPSGVPPGMPGQPPGGPPK-PWPEGPMANAA 293
Query: 499 PATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 543
T T +L +PP P P+ +P P P+MPP +P
Sbjct: 294 APTSTPQKL----IPPQPTGRPS-PAPPAVPPAASPVMPPQTQSP 333
Score = 55.1 bits (131), Expect = 2e-07
Identities = 80/283 (28%), Positives = 100/283 (35%), Gaps = 33/283 (11%)
Query: 275 PVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVP 334
P PP G P P P+ G P A GPS P G+ G P P S+ +P
Sbjct: 4 PDPPLG---GTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPP---SAGHPIP 57
Query: 335 VSGPSA----SDPWTPAPAFSDPWGGSPAKPSTN-----GTTAGGFDTEPDEFSDFDRLR 385
GP + P S G P N G +GG S D+
Sbjct: 58 TQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHS 117
Query: 386 TALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTP 445
P S G E + VPA P SG + S G+P A P + P
Sbjct: 118 QGYP---SPLGGSEHASSPVPASGPS----SGPQMSSGPG-GAPLDGADPQALGQQNRGP 169
Query: 446 ESF----LGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT 501
F L A + +++R P P + + + G P G P P P +
Sbjct: 170 TPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMA---VQGKRPMPGMQQQMPTLPPPSVS 226
Query: 502 LTLNQLRLSPVP-PVPG-APPTYISPLG-GGPGLPPMMPPGPP 541
T P P P PG APP Y P G GGP +PP P G P
Sbjct: 227 ATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVP 269
Score = 49.3 bits (116), Expect = 9e-06
Identities = 50/171 (29%), Positives = 64/171 (37%), Gaps = 33/171 (19%)
Query: 205 IRRGDDL--RLQMAIEESKRETGGKEESSLMDLADVF-TAPAPAPTTDPWGGPAPMAAAV 261
+ RG L LQMA++ + G +++ + V T P P P P GP P
Sbjct: 190 LARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGP----A 245
Query: 262 PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPW-GGTPAPAAGEG 320
P GGP +PP P P+ P P P G PW G A AA
Sbjct: 246 PPNYSRPHGMGGPNMPP---------PGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPT 296
Query: 321 PT------PDPWGSSDGGVPVSGPSAS---DPWTPAPAFSDPWGGSPAKPS 362
T P P G P P+AS P T +P G PA+P+
Sbjct: 297 STPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSP-------GQPAQPA 340
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.130 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,973,822
Number of Sequences: 37866
Number of extensions: 2418843
Number of successful extensions: 35320
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 502
Number of HSP's successfully gapped in prelim test: 1927
Number of HSP's that attempted gapping in prelim test: 13593
Number of HSP's gapped (non-prelim): 12542
length of query: 550
length of database: 18,247,518
effective HSP length: 107
effective length of query: 443
effective length of database: 14,195,856
effective search space: 6288764208
effective search space used: 6288764208
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.