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Search of human proteins with 41349497
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2
[Homo sapiens]
(529 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo... 1074 0.0
gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit ... 505 e-143
gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit... 505 e-143
gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit... 505 e-143
gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit... 505 e-143
gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit... 505 e-143
gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens] 64 3e-10
gi|4505999 protein phosphatase 1G [Homo sapiens] 62 2e-09
gi|29826282 protein phosphatase 1G [Homo sapiens] 62 2e-09
gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens] 57 4e-08
gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens] 57 4e-08
gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens] 57 4e-08
gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens] 57 4e-08
gi|13540531 integrin-linked kinase-associated protein phosphatas... 57 5e-08
gi|4505997 protein phosphatase 1D [Homo sapiens] 54 3e-07
gi|65506328 protein phosphatase 1J (PP2C domain containing) [Hom... 50 7e-06
gi|122937199 protein phosphatase 1B-like [Homo sapiens] 49 9e-06
gi|149944715 protein phosphatase 1H (PP2C domain containing) [Ho... 48 2e-05
gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens] 48 3e-05
gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens] 48 3e-05
gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens] 48 3e-05
gi|7661862 protein phosphatase 1F [Homo sapiens] 47 6e-05
gi|37221175 PH domain and leucine rich repeat protein phosphatas... 44 3e-04
gi|171460932 protein phosphatase 1M isoform a [Homo sapiens] 44 4e-04
gi|171460934 protein phosphatase 1M isoform b [Homo sapiens] 44 5e-04
gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho... 40 0.005
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 37 0.034
gi|5174703 mitogen-activated protein kinase kinase kinase 7 inte... 37 0.034
gi|41281798 mitogen-activated protein kinase kinase kinase 7 int... 37 0.034
gi|30089948 protein phosphatase 1E [Homo sapiens] 33 0.64
>gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo
sapiens]
Length = 529
Score = 1074 bits (2778), Expect = 0.0
Identities = 529/529 (100%), Positives = 529/529 (100%)
Query: 1 MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC 60
MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
Sbjct: 1 MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC 60
Query: 61 KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV 120
KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
Sbjct: 61 KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV 120
Query: 121 EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM 180
EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
Sbjct: 121 EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM 180
Query: 181 KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS 240
KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
Sbjct: 181 KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS 240
Query: 241 DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW 300
DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
Sbjct: 241 DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW 300
Query: 301 SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ 360
SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
Sbjct: 301 SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ 360
Query: 361 RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN 420
RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
Sbjct: 361 RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN 420
Query: 421 EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG 480
EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
Sbjct: 421 EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG 480
Query: 481 NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG 529
NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
Sbjct: 481 NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG 529
>gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 505 bits (1300), Expect = e-143
Identities = 257/469 (54%), Positives = 344/469 (73%), Gaps = 12/469 (2%)
Query: 64 RHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPVEDR 123
R+ ST + + L+P Q+N +L+A E + K+ + + + +S+L F+SNQL AN+P+EDR
Sbjct: 70 RYASTPQKFY---LTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDR 126
Query: 124 RGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMKPL 183
R A+CLQT G++ G+FDGH G AC+QAVSERLFYY+AVSL+ H+TL +E A+ES + L
Sbjct: 127 RSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRAL 186
Query: 184 LPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHM--EMGLSIEEALMYSFQRLDSD 241
LPIL W KHP D K+ + ++ + LR YWQEL+DL+ + ++EAL+ +F+RLD+D
Sbjct: 187 LPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDND 246
Query: 242 ISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWS 301
ISLE Q + L L+VAFSGATAC+AHVDG+ LHVAN GD RA+LGVQE++G WS
Sbjct: 247 ISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWS 306
Query: 302 CLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQR 361
+ L+ DHNA N+ EL RLK EHP+SE ++++ +DRLLG+L+P RAFGDV+ KWS +LQ+
Sbjct: 307 AVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQK 366
Query: 362 SILERGFNTEALNIY-QFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN 420
++E G + N Y +F PP+Y+TPPYLTAEPEVTYHRLRPQDKFLVLA+DGLW+ +
Sbjct: 367 RVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHR 426
Query: 421 EDVVRLVVGHLAEADWHKTDLA--QRPANLGLMQSLLLQR--KASGLHEADQNAATRLIR 476
+DVVR +VG H+ +A LG M LL +R K S + E DQNAAT LIR
Sbjct: 427 QDVVR-IVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFE-DQNAATHLIR 484
Query: 477 HAIGNNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAY 525
HA+GNNE+G ++ ERL+ ML+LPE+LARMYRDDIT+ VV FNS +GAY
Sbjct: 485 HAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAY 533
>gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 505 bits (1300), Expect = e-143
Identities = 257/469 (54%), Positives = 344/469 (73%), Gaps = 12/469 (2%)
Query: 64 RHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPVEDR 123
R+ ST + + L+P Q+N +L+A E + K+ + + + +S+L F+SNQL AN+P+EDR
Sbjct: 70 RYASTPQKFY---LTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDR 126
Query: 124 RGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMKPL 183
R A+CLQT G++ G+FDGH G AC+QAVSERLFYY+AVSL+ H+TL +E A+ES + L
Sbjct: 127 RSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRAL 186
Query: 184 LPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHM--EMGLSIEEALMYSFQRLDSD 241
LPIL W KHP D K+ + ++ + LR YWQEL+DL+ + ++EAL+ +F+RLD+D
Sbjct: 187 LPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDND 246
Query: 242 ISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWS 301
ISLE Q + L L+VAFSGATAC+AHVDG+ LHVAN GD RA+LGVQE++G WS
Sbjct: 247 ISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWS 306
Query: 302 CLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQR 361
+ L+ DHNA N+ EL RLK EHP+SE ++++ +DRLLG+L+P RAFGDV+ KWS +LQ+
Sbjct: 307 AVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQK 366
Query: 362 SILERGFNTEALNIY-QFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN 420
++E G + N Y +F PP+Y+TPPYLTAEPEVTYHRLRPQDKFLVLA+DGLW+ +
Sbjct: 367 RVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHR 426
Query: 421 EDVVRLVVGHLAEADWHKTDLA--QRPANLGLMQSLLLQR--KASGLHEADQNAATRLIR 476
+DVVR +VG H+ +A LG M LL +R K S + E DQNAAT LIR
Sbjct: 427 QDVVR-IVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFE-DQNAATHLIR 484
Query: 477 HAIGNNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAY 525
HA+GNNE+G ++ ERL+ ML+LPE+LARMYRDDIT+ VV FNS +GAY
Sbjct: 485 HAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAY 533
>gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 505 bits (1300), Expect = e-143
Identities = 257/469 (54%), Positives = 344/469 (73%), Gaps = 12/469 (2%)
Query: 64 RHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPVEDR 123
R+ ST + + L+P Q+N +L+A E + K+ + + + +S+L F+SNQL AN+P+EDR
Sbjct: 95 RYASTPQKFY---LTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDR 151
Query: 124 RGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMKPL 183
R A+CLQT G++ G+FDGH G AC+QAVSERLFYY+AVSL+ H+TL +E A+ES + L
Sbjct: 152 RSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRAL 211
Query: 184 LPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHM--EMGLSIEEALMYSFQRLDSD 241
LPIL W KHP D K+ + ++ + LR YWQEL+DL+ + ++EAL+ +F+RLD+D
Sbjct: 212 LPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDND 271
Query: 242 ISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWS 301
ISLE Q + L L+VAFSGATAC+AHVDG+ LHVAN GD RA+LGVQE++G WS
Sbjct: 272 ISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWS 331
Query: 302 CLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQR 361
+ L+ DHNA N+ EL RLK EHP+SE ++++ +DRLLG+L+P RAFGDV+ KWS +LQ+
Sbjct: 332 AVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQK 391
Query: 362 SILERGFNTEALNIY-QFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN 420
++E G + N Y +F PP+Y+TPPYLTAEPEVTYHRLRPQDKFLVLA+DGLW+ +
Sbjct: 392 RVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHR 451
Query: 421 EDVVRLVVGHLAEADWHKTDLA--QRPANLGLMQSLLLQR--KASGLHEADQNAATRLIR 476
+DVVR +VG H+ +A LG M LL +R K S + E DQNAAT LIR
Sbjct: 452 QDVVR-IVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFE-DQNAATHLIR 509
Query: 477 HAIGNNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAY 525
HA+GNNE+G ++ ERL+ ML+LPE+LARMYRDDIT+ VV FNS +GAY
Sbjct: 510 HAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAY 558
>gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 505 bits (1300), Expect = e-143
Identities = 257/469 (54%), Positives = 344/469 (73%), Gaps = 12/469 (2%)
Query: 64 RHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPVEDR 123
R+ ST + + L+P Q+N +L+A E + K+ + + + +S+L F+SNQL AN+P+EDR
Sbjct: 95 RYASTPQKFY---LTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDR 151
Query: 124 RGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMKPL 183
R A+CLQT G++ G+FDGH G AC+QAVSERLFYY+AVSL+ H+TL +E A+ES + L
Sbjct: 152 RSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRAL 211
Query: 184 LPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHM--EMGLSIEEALMYSFQRLDSD 241
LPIL W KHP D K+ + ++ + LR YWQEL+DL+ + ++EAL+ +F+RLD+D
Sbjct: 212 LPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDND 271
Query: 242 ISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWS 301
ISLE Q + L L+VAFSGATAC+AHVDG+ LHVAN GD RA+LGVQE++G WS
Sbjct: 272 ISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWS 331
Query: 302 CLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQR 361
+ L+ DHNA N+ EL RLK EHP+SE ++++ +DRLLG+L+P RAFGDV+ KWS +LQ+
Sbjct: 332 AVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQK 391
Query: 362 SILERGFNTEALNIY-QFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN 420
++E G + N Y +F PP+Y+TPPYLTAEPEVTYHRLRPQDKFLVLA+DGLW+ +
Sbjct: 392 RVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHR 451
Query: 421 EDVVRLVVGHLAEADWHKTDLA--QRPANLGLMQSLLLQR--KASGLHEADQNAATRLIR 476
+DVVR +VG H+ +A LG M LL +R K S + E DQNAAT LIR
Sbjct: 452 QDVVR-IVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFE-DQNAATHLIR 509
Query: 477 HAIGNNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAY 525
HA+GNNE+G ++ ERL+ ML+LPE+LARMYRDDIT+ VV FNS +GAY
Sbjct: 510 HAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAY 558
>gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 1 [Homo sapiens]
Length = 596
Score = 505 bits (1300), Expect = e-143
Identities = 257/469 (54%), Positives = 344/469 (73%), Gaps = 12/469 (2%)
Query: 64 RHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPVEDR 123
R+ ST + + L+P Q+N +L+A E + K+ + + + +S+L F+SNQL AN+P+EDR
Sbjct: 129 RYASTPQKFY---LTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDR 185
Query: 124 RGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMKPL 183
R A+CLQT G++ G+FDGH G AC+QAVSERLFYY+AVSL+ H+TL +E A+ES + L
Sbjct: 186 RSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRAL 245
Query: 184 LPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHM--EMGLSIEEALMYSFQRLDSD 241
LPIL W KHP D K+ + ++ + LR YWQEL+DL+ + ++EAL+ +F+RLD+D
Sbjct: 246 LPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDND 305
Query: 242 ISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWS 301
ISLE Q + L L+VAFSGATAC+AHVDG+ LHVAN GD RA+LGVQE++G WS
Sbjct: 306 ISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWS 365
Query: 302 CLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQR 361
+ L+ DHNA N+ EL RLK EHP+SE ++++ +DRLLG+L+P RAFGDV+ KWS +LQ+
Sbjct: 366 AVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQK 425
Query: 362 SILERGFNTEALNIY-QFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN 420
++E G + N Y +F PP+Y+TPPYLTAEPEVTYHRLRPQDKFLVLA+DGLW+ +
Sbjct: 426 RVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHR 485
Query: 421 EDVVRLVVGHLAEADWHKTDLA--QRPANLGLMQSLLLQR--KASGLHEADQNAATRLIR 476
+DVVR +VG H+ +A LG M LL +R K S + E DQNAAT LIR
Sbjct: 486 QDVVR-IVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFE-DQNAATHLIR 543
Query: 477 HAIGNNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAY 525
HA+GNNE+G ++ ERL+ ML+LPE+LARMYRDDIT+ VV FNS +GAY
Sbjct: 544 HAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAY 592
>gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]
Length = 360
Score = 64.3 bits (155), Expect = 3e-10
Identities = 80/317 (25%), Positives = 120/317 (37%), Gaps = 101/317 (31%)
Query: 120 VEDRRGVASCL--QTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAM 177
+EDR V + L +T+ +FGIFDGHGG E A
Sbjct: 105 MEDRFEVLTDLANKTHPSIFGIFDGHGG----------------------------ETAA 136
Query: 178 ESMKPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQR 237
E +K LP LK KD + L + + Q++L + EM
Sbjct: 137 EYVKSRLP--EALKQHLQDYEKDKENSVLSYQTILEQQILSIDREM-------------- 180
Query: 238 LDSDISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDN 297
L++ +G T +A + L VAN GD R +L ++ N
Sbjct: 181 -----------------LEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGN 223
Query: 298 GMWSCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSK 357
+PL+ DH + E R+KR + R+ G+L R+ GD LK
Sbjct: 224 ----AIPLSHDHKPYQLKERKRIKR---AGGFISFNGSWRVQGILAMSRSLGDYPLK--- 273
Query: 358 ELQRSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEV-TYHRLRPQDKFLVLASDGLWD 416
LN+ + +P++ T+ + Q +F++LASDGLWD
Sbjct: 274 --------------NLNV-------------VIPDPDILTFDLDKLQPEFMILASDGLWD 306
Query: 417 MLSNEDVVRLVVGHLAE 433
SNE+ VR + L E
Sbjct: 307 AFSNEEAVRFIKERLDE 323
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 61.6 bits (148), Expect = 2e-09
Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 33/171 (19%)
Query: 265 SGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREH 324
SG TA +A + G L VANAGD R ++ + L ++ DH ++ EL+R+K
Sbjct: 327 SGTTAVVALIRGKQLIVANAGDSRCVV-----SEAGKALDMSYDHKPEDEVELARIK--- 378
Query: 325 PESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYY 384
+ + M+ R+ G L RA GD K +K L PP
Sbjct: 379 --NAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNL--------------------PPE-- 414
Query: 385 TPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEAD 435
++A P++ L +F+V+A DG+W+++S+++VV + +++ D
Sbjct: 415 -EQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRD 464
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 61.6 bits (148), Expect = 2e-09
Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 33/171 (19%)
Query: 265 SGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREH 324
SG TA +A + G L VANAGD R ++ + L ++ DH ++ EL+R+K
Sbjct: 327 SGTTAVVALIRGKQLIVANAGDSRCVV-----SEAGKALDMSYDHKPEDEVELARIK--- 378
Query: 325 PESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYY 384
+ + M+ R+ G L RA GD K +K L PP
Sbjct: 379 --NAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNL--------------------PPE-- 414
Query: 385 TPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEAD 435
++A P++ L +F+V+A DG+W+++S+++VV + +++ D
Sbjct: 415 -EQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRD 464
>gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]
Length = 380
Score = 57.0 bits (136), Expect = 4e-08
Identities = 58/188 (30%), Positives = 83/188 (44%), Gaps = 39/188 (20%)
Query: 252 DEVTRNLS---LQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRD 308
DE RN S + SG+TA + H++ N GD RA+L NG C T+D
Sbjct: 114 DEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQ-VCFS-TQD 168
Query: 309 HNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGF 368
H N E R++ +M R+ G L RA GD K ++
Sbjct: 169 HKPCNPREKERIQNAGGS------VMIQRVNGSLAVSRALGDYDYK--------CVDGKG 214
Query: 369 NTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQ-DKFLVLASDGLWDMLSNEDVVRLV 427
TE L ++ EPEV Y LR + D+F++LA DG+WD++SNE++ V
Sbjct: 215 PTEQL---------------VSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
Query: 428 VGHLAEAD 435
L +D
Sbjct: 259 KSRLEVSD 266
>gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]
Length = 327
Score = 57.0 bits (136), Expect = 4e-08
Identities = 58/188 (30%), Positives = 83/188 (44%), Gaps = 39/188 (20%)
Query: 252 DEVTRNLS---LQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRD 308
DE RN S + SG+TA + H++ N GD RA+L NG C T+D
Sbjct: 114 DEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQ-VCFS-TQD 168
Query: 309 HNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGF 368
H N E R++ +M R+ G L RA GD K ++
Sbjct: 169 HKPCNPREKERIQNAGGS------VMIQRVNGSLAVSRALGDYDYK--------CVDGKG 214
Query: 369 NTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQ-DKFLVLASDGLWDMLSNEDVVRLV 427
TE L ++ EPEV Y LR + D+F++LA DG+WD++SNE++ V
Sbjct: 215 PTEQL---------------VSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
Query: 428 VGHLAEAD 435
L +D
Sbjct: 259 KSRLEVSD 266
>gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]
Length = 387
Score = 57.0 bits (136), Expect = 4e-08
Identities = 58/188 (30%), Positives = 83/188 (44%), Gaps = 39/188 (20%)
Query: 252 DEVTRNLS---LQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRD 308
DE RN S + SG+TA + H++ N GD RA+L NG C T+D
Sbjct: 114 DEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQ-VCFS-TQD 168
Query: 309 HNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGF 368
H N E R++ +M R+ G L RA GD K ++
Sbjct: 169 HKPCNPREKERIQNAGGS------VMIQRVNGSLAVSRALGDYDYK--------CVDGKG 214
Query: 369 NTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQ-DKFLVLASDGLWDMLSNEDVVRLV 427
TE L ++ EPEV Y LR + D+F++LA DG+WD++SNE++ V
Sbjct: 215 PTEQL---------------VSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
Query: 428 VGHLAEAD 435
L +D
Sbjct: 259 KSRLEVSD 266
>gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]
Length = 479
Score = 57.0 bits (136), Expect = 4e-08
Identities = 58/188 (30%), Positives = 83/188 (44%), Gaps = 39/188 (20%)
Query: 252 DEVTRNLS---LQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRD 308
DE RN S + SG+TA + H++ N GD RA+L NG C T+D
Sbjct: 114 DEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQ-VCFS-TQD 168
Query: 309 HNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGF 368
H N E R++ +M R+ G L RA GD K ++
Sbjct: 169 HKPCNPREKERIQNAGGS------VMIQRVNGSLAVSRALGDYDYK--------CVDGKG 214
Query: 369 NTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQ-DKFLVLASDGLWDMLSNEDVVRLV 427
TE L ++ EPEV Y LR + D+F++LA DG+WD++SNE++ V
Sbjct: 215 PTEQL---------------VSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
Query: 428 VGHLAEAD 435
L +D
Sbjct: 259 KSRLEVSD 266
>gi|13540531 integrin-linked kinase-associated protein phosphatase
2C [Homo sapiens]
Length = 392
Score = 56.6 bits (135), Expect = 5e-08
Identities = 47/170 (27%), Positives = 79/170 (46%), Gaps = 40/170 (23%)
Query: 266 GATA-CMAHVDGIHLHVANAGDCRAIL-GVQEDNGMWSCLPLTRDHNAWNQAELSRLKRE 323
G+TA C+ VD I L++AN GD RAIL E++ + L L+++HN E R+++
Sbjct: 216 GSTATCVLAVDNI-LYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKA 274
Query: 324 HPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHY 383
+ + R+LGVL R+ GD Q
Sbjct: 275 GGN------VRDGRVLGVLEVSRSIGDGQ------------------------------- 297
Query: 384 YTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAE 433
Y +T+ P++ +L P D+F++LA DGL+ + + E+ V ++ L +
Sbjct: 298 YKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLED 347
>gi|4505997 protein phosphatase 1D [Homo sapiens]
Length = 605
Score = 54.3 bits (129), Expect = 3e-07
Identities = 44/184 (23%), Positives = 79/184 (42%), Gaps = 48/184 (26%)
Query: 265 SGATACMAHVDGIHLHVANAGDCRAILGVQED--NGMWSCLPLTRDH------------- 309
SG TA + + G+ ++VA+ GD +LG+Q+D + + +T+DH
Sbjct: 171 SGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEG 230
Query: 310 ---NAWNQAELSRLKREHPESEDRTIIMEDRLLG---VLIPCRAFGDVQLKWSKELQRSI 363
+ N++ ++R+ + P + ++ L RA GD+ WS
Sbjct: 231 LGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDL---WS------- 280
Query: 364 LERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQD-KFLVLASDGLWDMLSNED 422
Y F + P EP+ + H L PQ K+++L SDGLW+M+ +D
Sbjct: 281 ------------YDFFSGEFVVSP----EPDTSVHTLDPQKHKYIILGSDGLWNMIPPQD 324
Query: 423 VVRL 426
+ +
Sbjct: 325 AISM 328
>gi|65506328 protein phosphatase 1J (PP2C domain containing) [Homo
sapiens]
Length = 505
Score = 49.7 bits (117), Expect = 7e-06
Identities = 89/376 (23%), Positives = 148/376 (39%), Gaps = 73/376 (19%)
Query: 84 EVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPVEDRRGVASCLQTNGLMFGIFDGH 143
EV+ AG++ H E + V+ E + P E RG C +G+FDGH
Sbjct: 109 EVINAGKSRHN----EDQACCEVVYVEGRRSVTGVPREPSRGQGLCFY----YWGLFDGH 160
Query: 144 GGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMK-PLLPILHWLKHPGDSIYKDVT 202
G A+ S L ++ E ++ +E ++ P P L PG D +
Sbjct: 161 AGGGAAEMASRLLHRHIR---------EQLKDLVEILQDPSPPPLCLPTTPGTPDSSDPS 211
Query: 203 SVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDSDISLEIQAPLEDEVTRNLSLQV 262
HL + W ++ E + A+ +FQ +D ++ E + QV
Sbjct: 212 --HLLGPQSCWSSQKEVSHES--LVVGAVENAFQLMDEQMARERRGH-----------QV 256
Query: 263 AFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAE----LS 318
+ ++ G ++VANAGD RAI+ NG +P++R+ + + L
Sbjct: 257 EGGCCALVVIYLLG-KVYVANAGDSRAII---VRNG--EIIPMSREFTPETERQRLQLLG 310
Query: 319 RLKREHPESEDRTIIMEDRLLGVLIPCR-----------AFGDVQL------------KW 355
LK E SE + R+L + R A+ ++L K
Sbjct: 311 FLKPELLGSEFTHLEFPRRVLPKELGQRMLYRDQNMTGWAYKKIELEDLRFPLVCGEGKK 370
Query: 356 SKELQRSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRP----QDKFLVLAS 411
++ + + RG +L + T P P+L+ PEV + L D LVL +
Sbjct: 371 ARVMATIGVTRGLGDHSLKVCSSTLP---IKPFLSCFPEVRVYDLTQYEHCPDDVLVLGT 427
Query: 412 DGLWDMLSNEDVVRLV 427
DGLWD+ ++ +V V
Sbjct: 428 DGLWDVTTDCEVAATV 443
>gi|122937199 protein phosphatase 1B-like [Homo sapiens]
Length = 430
Score = 49.3 bits (116), Expect = 9e-06
Identities = 52/180 (28%), Positives = 74/180 (41%), Gaps = 34/180 (18%)
Query: 252 DEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNA 311
DE R+L +V G TA + V L++A+ GD RA+L + + T DH
Sbjct: 148 DERLRSLWPRVETGGCTAVVLLVSPRFLYLAHCGDSRAVL-----SRAGAVAFSTEDHRP 202
Query: 312 WNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTE 371
E RE + TI R+ G L RA GD K +
Sbjct: 203 LRPRE-----RERIHAAGGTI-RRRRVEGSLAVSRALGDFTYKEAPG------------- 243
Query: 372 ALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHL 431
PP ++AEPEV + +D+F++LASDG+WD +S + LV L
Sbjct: 244 -------RPPELQL---VSAEPEVAALARQAEDEFMLLASDGVWDTVSGAALAGLVASRL 293
>gi|149944715 protein phosphatase 1H (PP2C domain containing) [Homo
sapiens]
Length = 514
Score = 48.1 bits (113), Expect = 2e-05
Identities = 102/419 (24%), Positives = 159/419 (37%), Gaps = 97/419 (23%)
Query: 67 STEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPVEDRRGV 126
ST +D Q S E + +AG T S+ +S+ E QL NS E
Sbjct: 89 STHNED---QASCEVLTVKKKAGAVTSTPNRNSSKRRSSLPNGEGLQLKENSESEG---- 141
Query: 127 ASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMK--PLL 184
SC + +FDGH G A VA L+ H E ++ ++ +K +L
Sbjct: 142 VSCHY-----WSLFDGHAGSGAA---------VVASRLLQHHITEQLQDIVDILKNSAVL 187
Query: 185 PILHWLKHPGDSIYKDVTSVHLDHLRV--------------YWQELLDLHMEMGLSIEEA 230
P + P ++ T LR ++ E H + + A
Sbjct: 188 PPTCLGEEPENTPANSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIG---A 244
Query: 231 LMYSFQRLDSDISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAI 290
L +F+ +D I E + N+S G TA + L+VANAGD RAI
Sbjct: 245 LESAFKEMDLQIERE-------RSSYNIS-----GGCTALIVICLLGKLYVANAGDSRAI 292
Query: 291 LGVQEDNGMWSCLPLTRDHN-----------AWNQAELSRLKREHPESEDRTIIMEDRLL 339
+ NG +P++ + A+ Q L + H E R ++ + L
Sbjct: 293 I---IRNG--EIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRR---VQRKEL 344
Query: 340 GVLIPCRAFG----------DVQLKW---------SKELQRSILERGFNTEALNIYQFTP 380
G + R F D LK+ ++ + + RG L ++
Sbjct: 345 GKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHD--- 401
Query: 381 PHYYTPPYLTAEPEVTYHRLRP----QDKFLVLASDGLWDMLSNEDVVRLVVGHLAEAD 435
+ Y P+L++ PEV + L D L+LA+DGLWD+LSNE+V + L D
Sbjct: 402 SNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCD 460
>gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]
Length = 382
Score = 47.8 bits (112), Expect = 3e-05
Identities = 45/172 (26%), Positives = 65/172 (37%), Gaps = 35/172 (20%)
Query: 265 SGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREH 324
SG+TA + H + N GD R +L + T+DH N E R++
Sbjct: 125 SGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFF-----TQDHKPSNPLEKERIQNAG 179
Query: 325 PESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYY 384
+M R+ G L RA GD K ++ P
Sbjct: 180 GS------VMIQRVNGSLAVSRALGDFDYKC-------------------VHGKGPTEQL 214
Query: 385 TPPYLTAEPEV-TYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEAD 435
P EPEV R D+F++LA DG+WD++ NE++ V L D
Sbjct: 215 VSP----EPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTD 262
>gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]
Length = 324
Score = 47.8 bits (112), Expect = 3e-05
Identities = 45/172 (26%), Positives = 65/172 (37%), Gaps = 35/172 (20%)
Query: 265 SGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREH 324
SG+TA + H + N GD R +L + T+DH N E R++
Sbjct: 125 SGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFF-----TQDHKPSNPLEKERIQNAG 179
Query: 325 PESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYY 384
+M R+ G L RA GD K ++ P
Sbjct: 180 GS------VMIQRVNGSLAVSRALGDFDYKC-------------------VHGKGPTEQL 214
Query: 385 TPPYLTAEPEV-TYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEAD 435
P EPEV R D+F++LA DG+WD++ NE++ V L D
Sbjct: 215 VSP----EPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTD 262
>gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]
Length = 455
Score = 47.8 bits (112), Expect = 3e-05
Identities = 45/172 (26%), Positives = 65/172 (37%), Gaps = 35/172 (20%)
Query: 265 SGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREH 324
SG+TA + H + N GD R +L + T+DH N E R++
Sbjct: 198 SGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFF-----TQDHKPSNPLEKERIQNAG 252
Query: 325 PESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYY 384
+M R+ G L RA GD K ++ P
Sbjct: 253 GS------VMIQRVNGSLAVSRALGDFDYKC-------------------VHGKGPTEQL 287
Query: 385 TPPYLTAEPEV-TYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEAD 435
P EPEV R D+F++LA DG+WD++ NE++ V L D
Sbjct: 288 VSP----EPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTD 335
>gi|7661862 protein phosphatase 1F [Homo sapiens]
Length = 454
Score = 46.6 bits (109), Expect = 6e-05
Identities = 51/203 (25%), Positives = 80/203 (39%), Gaps = 53/203 (26%)
Query: 265 SGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREH 324
SG T A + G LHVA GD + IL VQ+ + L H Q E +R+
Sbjct: 253 SGTTGVCALIAGATLHVAWLGDSQVIL-VQQGQ----VVKLMEPHRPERQDEKARI---- 303
Query: 325 PESEDRTIIMED--RLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPH 382
E+ + D R+ G L RA GDV
Sbjct: 304 -EALGGFVSHMDCWRVNGTLAVSRAIGDV------------------------------- 331
Query: 383 YYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEADWHKTDLA 442
+ PY++ E + L + +L+LA DG +D++ +++VV LV HL
Sbjct: 332 -FQKPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTR--------- 381
Query: 443 QRPANLGLMQSLLLQRKASGLHE 465
Q+ + L + + L+ + G H+
Sbjct: 382 QQGSGLRVAEELVAAARERGSHD 404
>gi|37221175 PH domain and leucine rich repeat protein phosphatase
[Homo sapiens]
Length = 1205
Score = 44.3 bits (103), Expect = 3e-04
Identities = 45/147 (30%), Positives = 61/147 (41%), Gaps = 44/147 (29%)
Query: 282 ANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMED-RLLG 340
AN G C+ +L NG LPL+R + + EL R+K+ + II ED ++ G
Sbjct: 774 ANVGKCQTVLC---RNG--KPLPLSRSYIMSCEEELKRIKQH------KAIITEDGKVNG 822
Query: 341 VLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRL 400
V TE+ I +T H P + P V L
Sbjct: 823 V----------------------------TESTRILGYTFLH----PSVVPRPHVQSVLL 850
Query: 401 RPQDKFLVLASDGLWDMLSNEDVVRLV 427
PQD+F +L S GLWD LS E+ V V
Sbjct: 851 TPQDEFFILGSKGLWDSLSVEEAVEAV 877
>gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]
Length = 298
Score = 43.9 bits (102), Expect = 4e-04
Identities = 69/261 (26%), Positives = 100/261 (38%), Gaps = 95/261 (36%)
Query: 222 EMGLSIEE----ALMYSFQRLDSDISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGI 277
E G+ E+ AL +FQ D I E++A + G TA +A
Sbjct: 18 EKGIRAEDLVIGALESAFQECDEVIGRELEASGQ------------MGGCTALVAVSLQG 65
Query: 278 HLHVANAGDCRAILGVQEDN-----------------------------GMWSCLP---- 304
L++ANAGD RAIL V+ D G ++ L
Sbjct: 66 KLYMANAGDSRAIL-VRRDEIRPLSFEFTPETERQRIQQLAFVYPELLAGEFTRLEFPRR 124
Query: 305 ----------LTRDHN----AWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGD 350
L RDH+ ++ + E S LK + R + RLLG L R GD
Sbjct: 125 LKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGR----QARLLGTLAVSRGLGD 180
Query: 351 VQLKWSKELQRSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRP----QDKF 406
QL+ +L+ + P+L + P+VT + +D
Sbjct: 181 HQLR--------VLDTNIQLK---------------PFLLSVPQVTVLDVDQLELQEDDV 217
Query: 407 LVLASDGLWDMLSNEDVVRLV 427
+V+A+DGLWD+LSNE V LV
Sbjct: 218 VVMATDGLWDVLSNEQVAWLV 238
>gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]
Length = 247
Score = 43.5 bits (101), Expect = 5e-04
Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 35/131 (26%)
Query: 305 LTRDHN----AWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ 360
L RDH+ ++ + E S LK + R + RLLG L R GD QL+
Sbjct: 84 LFRDHHMSGWSYKRVEKSDLKYPLIHGQGR----QARLLGTLAVSRGLGDHQLR------ 133
Query: 361 RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRP----QDKFLVLASDGLWD 416
+L+ + P+L + P+VT + +D +V+A+DGLWD
Sbjct: 134 --VLDTNIQLK---------------PFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWD 176
Query: 417 MLSNEDVVRLV 427
+LSNE V LV
Sbjct: 177 VLSNEQVAWLV 187
>gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo
sapiens]
Length = 372
Score = 40.0 bits (92), Expect = 0.005
Identities = 47/186 (25%), Positives = 72/186 (38%), Gaps = 39/186 (20%)
Query: 244 LEIQAPLEDEVTRNLSLQVAFSGATACMAHV-DGIHLHVANAGDCRAILGVQEDNGMWSC 302
LEI + + SG TA +A + DGI L VA+ GD RAIL +
Sbjct: 165 LEIDKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKP----- 219
Query: 303 LPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRS 362
+ LT DH + E R+K+ G + + G + + RS
Sbjct: 220 MKLTIDHTPERKDEKERIKK----------------CGGFVAWNSLGQPHVNGRLAMTRS 263
Query: 363 ILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLR-PQDKFLVLASDGLWDMLSNE 421
I + T + AEPE +L D FLVL +DG+ M++++
Sbjct: 264 IGDLDLKTSGV----------------IAEPETKRIKLHHADDSFLVLTTDGINFMVNSQ 307
Query: 422 DVVRLV 427
++ V
Sbjct: 308 EICDFV 313
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 37.4 bits (85), Expect = 0.034
Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 8/95 (8%)
Query: 151 AVSERLFYYVAVSLMSHQTLEHMEGAMESMKPLLPILHWLKHPG----DSIYKDVTSVHL 206
A +R VA+ ++ + LE EG+ME+ + +LH +KHP D IY+ ++L
Sbjct: 37 AEDKRTQKLVAIKCIAKEALEGKEGSMENE---IAVLHKIKHPNIVALDDIYESGGHLYL 93
Query: 207 DHLRVYWQELLDLHMEMGLSIE-EALMYSFQRLDS 240
V EL D +E G E +A FQ LD+
Sbjct: 94 IMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDA 128
>gi|5174703 mitogen-activated protein kinase kinase kinase 7
interacting protein 1 isoform alpha [Homo sapiens]
Length = 504
Score = 37.4 bits (85), Expect = 0.034
Identities = 70/292 (23%), Positives = 117/292 (40%), Gaps = 58/292 (19%)
Query: 131 QTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMKPLLPILHWL 190
+ N ++G+F+G+ G+ V++RL A L+ EH E + + LL
Sbjct: 59 ENNCFLYGVFNGYDGNRVTNFVAQRLS---AELLLGQLNAEHAEADVRRV--LL------ 107
Query: 191 KHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSI-EEALMYSFQRLDSDISLEIQAP 249
+ V L+ + E L ++ + + L +Q++ LE
Sbjct: 108 -----QAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKI-----LERLKT 157
Query: 250 LEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDH 309
LE E++ GA A +A + L+VAN G RA+L +G+ L DH
Sbjct: 158 LEREIS---------GGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGL-QVTQLNVDH 207
Query: 310 NAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFN 369
N+ EL RL + D I + ++ R GD ++K+ +
Sbjct: 208 TTENEDELFRLSQ---LGLDAGKIKQVGIICGQESTRRIGDYKVKYGYT----------D 254
Query: 370 TEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQD---KFLVLASDGLWDML 418
+ L+ + P + AEPE+ H +P D FLVL S+GL+ L
Sbjct: 255 IDLLSAAKSKP--------IIAEPEI--HGAQPLDGVTGFLVLMSEGLYKAL 296
>gi|41281798 mitogen-activated protein kinase kinase kinase 7
interacting protein 1 isoform beta [Homo sapiens]
Length = 462
Score = 37.4 bits (85), Expect = 0.034
Identities = 70/292 (23%), Positives = 117/292 (40%), Gaps = 58/292 (19%)
Query: 131 QTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMKPLLPILHWL 190
+ N ++G+F+G+ G+ V++RL A L+ EH E + + LL
Sbjct: 59 ENNCFLYGVFNGYDGNRVTNFVAQRLS---AELLLGQLNAEHAEADVRRV--LL------ 107
Query: 191 KHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSI-EEALMYSFQRLDSDISLEIQAP 249
+ V L+ + E L ++ + + L +Q++ LE
Sbjct: 108 -----QAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKI-----LERLKT 157
Query: 250 LEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDH 309
LE E++ GA A +A + L+VAN G RA+L +G+ L DH
Sbjct: 158 LEREIS---------GGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGL-QVTQLNVDH 207
Query: 310 NAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFN 369
N+ EL RL + D I + ++ R GD ++K+ +
Sbjct: 208 TTENEDELFRLSQ---LGLDAGKIKQVGIICGQESTRRIGDYKVKYGYT----------D 254
Query: 370 TEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQD---KFLVLASDGLWDML 418
+ L+ + P + AEPE+ H +P D FLVL S+GL+ L
Sbjct: 255 IDLLSAAKSKP--------IIAEPEI--HGAQPLDGVTGFLVLMSEGLYKAL 296
>gi|30089948 protein phosphatase 1E [Homo sapiens]
Length = 755
Score = 33.1 bits (74), Expect = 0.64
Identities = 15/58 (25%), Positives = 32/58 (55%)
Query: 387 PYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEADWHKTDLAQR 444
PY+ + + L + +L+LA DG +D ++ ++ V++V HL E + + +A +
Sbjct: 410 PYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHK 467
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,301,794
Number of Sequences: 37866
Number of extensions: 898423
Number of successful extensions: 2202
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2112
Number of HSP's gapped (non-prelim): 81
length of query: 529
length of database: 18,247,518
effective HSP length: 107
effective length of query: 422
effective length of database: 14,195,856
effective search space: 5990651232
effective search space used: 5990651232
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.