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Search of human proteins with 41281782
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo
sapiens]
(592 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo sap... 1201 0.0
gi|116734691 signal peptide peptidase-like 2B isoform 3 [Homo sa... 1019 0.0
gi|21314755 signal peptide peptidase-like 2A [Homo sapiens] 489 e-138
gi|38524591 intramembrane protease 5 [Homo sapiens] 489 e-138
gi|33413418 signal peptide peptidase 3 [Homo sapiens] 109 8e-24
gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo ... 93 8e-19
gi|30581109 minor histocompatibility antigen 13 isoform 2 [Homo ... 92 1e-18
gi|23308607 minor histocompatibility antigen 13 isoform 1 [Homo ... 86 1e-16
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 44 4e-04
gi|150170670 piccolo isoform 2 [Homo sapiens] 44 5e-04
gi|150378539 piccolo isoform 1 [Homo sapiens] 44 5e-04
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 43 7e-04
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 43 7e-04
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 42 0.001
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 42 0.002
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 42 0.002
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 42 0.002
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 42 0.002
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 42 0.002
gi|4557317 annexin A11 [Homo sapiens] 42 0.002
gi|22165433 annexin A11 [Homo sapiens] 42 0.002
gi|22165431 annexin A11 [Homo sapiens] 42 0.002
gi|122937321 UNC homeobox [Homo sapiens] 42 0.002
gi|55741677 SET domain containing 1A [Homo sapiens] 41 0.003
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 41 0.003
gi|238859557 regulatory factor X1 [Homo sapiens] 41 0.004
gi|33286446 opioid growth factor receptor [Homo sapiens] 41 0.004
gi|239754991 PREDICTED: hypothetical protein isoform 1 [Homo sap... 41 0.004
gi|160707881 formin 2 [Homo sapiens] 41 0.004
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 41 0.004
>gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo
sapiens]
Length = 592
Score = 1201 bits (3108), Expect = 0.0
Identities = 592/592 (100%), Positives = 592/592 (100%)
Query: 1 MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLS 60
MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLS
Sbjct: 1 MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLS 60
Query: 61 KASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR 120
KASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR
Sbjct: 61 KASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR 120
Query: 121 ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFI 180
ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFI
Sbjct: 121 ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFI 180
Query: 181 MAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLL 240
MAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLL
Sbjct: 181 MAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLL 240
Query: 241 YYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLL 300
YYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLL
Sbjct: 241 YYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLL 300
Query: 301 ALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDI 360
ALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDI
Sbjct: 301 ALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDI 360
Query: 361 FFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG 420
FFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG
Sbjct: 361 FFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG 420
Query: 421 DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPC 480
DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPC
Sbjct: 421 DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPC 480
Query: 481 TLVTSCAVALWRRELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEP 540
TLVTSCAVALWRRELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEP
Sbjct: 481 TLVTSCAVALWRRELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEP 540
Query: 541 ATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAESEGRDQAQPSPVTQPGASA 592
ATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAESEGRDQAQPSPVTQPGASA
Sbjct: 541 ATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAESEGRDQAQPSPVTQPGASA 592
>gi|116734691 signal peptide peptidase-like 2B isoform 3 [Homo
sapiens]
Length = 511
Score = 1019 bits (2636), Expect = 0.0
Identities = 505/505 (100%), Positives = 505/505 (100%)
Query: 1 MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLS 60
MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLS
Sbjct: 1 MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLS 60
Query: 61 KASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR 120
KASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR
Sbjct: 61 KASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR 120
Query: 121 ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFI 180
ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFI
Sbjct: 121 ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFI 180
Query: 181 MAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLL 240
MAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLL
Sbjct: 181 MAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLL 240
Query: 241 YYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLL 300
YYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLL
Sbjct: 241 YYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLL 300
Query: 301 ALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDI 360
ALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDI
Sbjct: 301 ALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDI 360
Query: 361 FFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG 420
FFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG
Sbjct: 361 FFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG 420
Query: 421 DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPC 480
DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPC
Sbjct: 421 DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPC 480
Query: 481 TLVTSCAVALWRRELGVFWTGSGFA 505
TLVTSCAVALWRRELGVFWTGSGFA
Sbjct: 481 TLVTSCAVALWRRELGVFWTGSGFA 505
>gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]
Length = 520
Score = 489 bits (1260), Expect = e-138
Identities = 239/503 (47%), Positives = 344/503 (68%), Gaps = 17/503 (3%)
Query: 5 VAAALARLLAAFLL--LAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLSKA 62
++ A A LL FLL AAQ A ++ +G KDYC+LYNP W LP L A
Sbjct: 7 LSPAGAALLWGFLLQLTAAQEA-------ILHASGNGTTKDYCMLYNPYWTALPSTLENA 59
Query: 63 SFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSRER 122
+ + L N T++ LC+ +D+P G ++ +V G+C F EK R+AQ GA +L+V+
Sbjct: 60 TSISLMNLTSTPLCNLSDIPPVGIKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVNNSV 119
Query: 123 LVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFIMA 182
L PP GN++++ ++ I +A +SYKD D+ G + +Y+P P DY MV+IF++A
Sbjct: 120 LFPPSGNRSEFPDVKILIAFISYKDFRDMNQTLGDNITVKMYSPSWPNFDYTMVVIFVIA 179
Query: 183 VGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLLYY 242
V TVA+GGYW+G +++ D K+++E + +P+ +FVV+CC M+VLLY+
Sbjct: 180 VFTVALGGYWSGLVELENLKAVTTEDREMRKKKEEYLTFSPLTVVIFVVICCVMMVLLYF 239
Query: 243 FYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLLAL 302
FY LVYV+I IFC+ASA LY+CLA + ++P+G+C I K + R++ L+
Sbjct: 240 FYKWLVYVMIAIFCIASAMSLYNCLAALIHKIPYGQCTIACRG-----KNMEVRLIFLSG 294
Query: 303 FCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFF 362
C+AV+VVW VFRNED+WAW+LQD LGIAFCL ++KT++LP FK+C +LL +L LYD+FF
Sbjct: 295 LCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFF 354
Query: 363 VFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRL-NSSPLALCDRPFSLLGFGD 421
VFITPF+TK+G SIMVE+A GP EKLP+V++VP+L S +++C P S+LGFGD
Sbjct: 355 VFITPFITKNGESIMVELAAGP--FGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGD 412
Query: 422 ILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCT 481
I+VPGLL+AYC RFD+Q SS +Y+V+ T+AY +G+++TFV L LM++GQPALLYLVPCT
Sbjct: 413 IIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPALLYLVPCT 472
Query: 482 LVTSCAVALWRRELGVFWTGSGF 504
L+T+ VA R+E+ FW G+ +
Sbjct: 473 LITASVVAWRRKEMKKFWKGNSY 495
>gi|38524591 intramembrane protease 5 [Homo sapiens]
Length = 684
Score = 489 bits (1258), Expect = e-138
Identities = 287/624 (45%), Positives = 366/624 (58%), Gaps = 53/624 (8%)
Query: 12 LLAAFLLLAAQVAC-EYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLSKASFLQLRNW 70
L FLLL + VA +YG+ HVVS+ KDYCIL++ + LP DL A L L +
Sbjct: 8 LPVGFLLLISTVAGGKYGVAHVVSENWS---KDYCILFSSDYITLPRDLHHAPLLPLYDG 64
Query: 71 TASLLCSAADLP---------ARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR- 120
T + C D P R +V RGNC+F+ K LAQG GA GLLIVSR
Sbjct: 65 TKAPWCPGEDSPHQAQLRSPSQRPLRQTTAMVMRGNCSFHTKGWLAQGQGAHGLLIVSRV 124
Query: 121 ------ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIF--TRFGRTVRAALYAPKEPVLD 172
+ + P + ++ IPVA+L Y DMLDI TR VR A+YAP EP++D
Sbjct: 125 SDQQCSDTTLAPQDPRQPLADLTIPVAMLHYADMLDILSHTRGEAVVRVAMYAPPEPIID 184
Query: 173 YNMVIIFIMAVGTVAIGGYWAGSRDVKKRYMKHKRDDG------------------PEKQ 214
YNM++IFI+AVGTVA GGYWAG + + + R G E
Sbjct: 185 YNMLVIFILAVGTVAAGGYWAGLTEANRLQRRRARRGGGSGGHHQLQEAAAAEGAQKEDN 244
Query: 215 EDEAVDVTPVMTCVFVVMCCSMLVLLYYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRL 274
ED VD TP MT V V + CS+++LLY+FYD VYV IGIF L + GLYSCL+P V L
Sbjct: 245 EDIPVDFTPAMTGVVVTLSCSLMLLLYFFYDHFVYVTIGIFGLGAGIGLYSCLSPLVCHL 304
Query: 275 PFGKCRIPNNSLPYFHKRPQARMLLLALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCL 334
+ + P +SL P +LLLA C V + W +RNED+WAW+LQD LGI++CL
Sbjct: 305 SLRQYQRPPHSLWASLPLP---LLLLASLCATVIIFWVAYRNEDRWAWLLQDTLGISYCL 361
Query: 335 YMLKTIRLPTFKACTLLLLVLFLYDIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLP 394
++L +RLPT K C+ LL L +D+FFVF+TPF TK+G SIM +VA GP++S++ E+LP
Sbjct: 362 FVLHRVRLPTLKNCSSFLLALLAFDVFFVFVTPFFTKTGESIMAQVALGPAESSSHERLP 421
Query: 395 MVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYG 454
MVLKVPRL S L LC +PFS+LGFGDI+VPG LVAYC RFD+QV S ++YFVACT+AY
Sbjct: 422 MVLKVPRLRVSALTLCSQPFSILGFGDIVVPGFLVAYCCRFDVQVCSRQIYFVACTVAYA 481
Query: 455 VGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRRELGVFWTGSGFAKVLPPSPWA 514
VGLLVTF+A+ LMQ GQPALLYLV TL+TS AVA R+EL +FWTG G AK+
Sbjct: 482 VGLLVTFMAMVLMQMGQPALLYLVSSTLLTSLAVAACRQELSLFWTGQGRAKM---CGLG 538
Query: 515 PAPADGPQPPKDSATPLSPQPPSEEPAT------SPWPAEQSPKSRTSEEMGAGAPM-RE 567
AP+ G + ++ A E + P E + + T E A P R
Sbjct: 539 CAPSAGSRQKQEGAADAHTASTLERGTSRGAGDLDSNPGEDTTEIVTISENEATNPEDRS 598
Query: 568 PGSPAESEGRDQAQPSPVTQPGAS 591
S S+ P PGAS
Sbjct: 599 DSSEGWSDAHLDPNELPFIPPGAS 622
>gi|33413418 signal peptide peptidase 3 [Homo sapiens]
Length = 384
Score = 109 bits (272), Expect = 8e-24
Identities = 97/306 (31%), Positives = 145/306 (47%), Gaps = 59/306 (19%)
Query: 235 SMLVLLYYFYDLLVYVVIGIFCLASATGLYSCLAPCV---------RRLPFGKCRIPNNS 285
S+LV+ ++F + V I LA+ + L C ++ FG C
Sbjct: 83 SLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCG----- 137
Query: 286 LPYFHKRPQARMLLLALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTF 345
R A LL V + ++W + + W+L DAL + C+ M+ +RLP+
Sbjct: 138 ------RFTAAELLSFSLSVMLVLIWVLTGH-----WLLMDALAMGLCVAMIAFVRLPSL 186
Query: 346 KACTLLLLVLFLYDIFFVFITPFLTKSGSSIMVEVATGPSDS---ATREKL---PMVLK- 398
K LLL L +YD+F+VF + ++ S++MV+VAT P+D+ KL P V +
Sbjct: 187 KVSCLLLSGLLIYDVFWVFFSAYI--FNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRD 244
Query: 399 VPRLNSSPLAL-----CDRPFSLLGFGDILVPGLLVAYCHRFD----------------- 436
VPRL S P L FS+LG GDI++PGLL+ + R+D
Sbjct: 245 VPRL-SLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGAPGPA 303
Query: 437 -IQVQSSRVYFVACT-IAYGVGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRRE 494
I + +V + CT I Y VGLL VA + + QPALLYLVP TL+ +A + +
Sbjct: 304 NISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGD 363
Query: 495 LGVFWT 500
L W+
Sbjct: 364 LRRMWS 369
>gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo
sapiens]
Length = 426
Score = 92.8 bits (229), Expect = 8e-19
Identities = 79/286 (27%), Positives = 130/286 (45%), Gaps = 34/286 (11%)
Query: 302 LFCVAVSV---VWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLY 358
L C+ +S VW + R W+ + G+AF L ++ + L +LL LF+Y
Sbjct: 163 LVCLGLSSIVGVWYLLRKH----WIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIY 218
Query: 359 DIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLG 418
D+F+VF G+++MV VA + P+ L P+ + L F++LG
Sbjct: 219 DVFWVF--------GTNVMVTVAKS-------FEAPIKLVFPQ-DLLEKGLEANNFAMLG 262
Query: 419 FGDILVPGLLVAYCHRFDIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYL 477
GD+++PG+ +A RFDI ++ ++ YF AY GL +T + + + QPALLYL
Sbjct: 263 LGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYL 322
Query: 478 VPCTLVTSCAVALWRRELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPS 537
VP + VAL + E+ ++ A++LP +P P S +P S
Sbjct: 323 VPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRL------THFPTVSGSPASLADSM 376
Query: 538 EEPATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAESEGRDQAQPS 583
++ P S EE ++P + ES+ +A S
Sbjct: 377 QQKLAGPRRRRPQNPSAIYEESNP----KDPAAVTESKEGTEASAS 418
>gi|30581109 minor histocompatibility antigen 13 isoform 2 [Homo
sapiens]
Length = 394
Score = 92.4 bits (228), Expect = 1e-18
Identities = 66/215 (30%), Positives = 109/215 (50%), Gaps = 24/215 (11%)
Query: 302 LFCVAVSV---VWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLY 358
L C+ +S VW + R W+ + G+AF L ++ + L +LL LF+Y
Sbjct: 163 LVCLGLSSIVGVWYLLRKH----WIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIY 218
Query: 359 DIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLG 418
D+F+VF G+++MV VA + P+ L P+ + L F++LG
Sbjct: 219 DVFWVF--------GTNVMVTVAKS-------FEAPIKLVFPQ-DLLEKGLEANNFAMLG 262
Query: 419 FGDILVPGLLVAYCHRFDIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYL 477
GD+++PG+ +A RFDI ++ ++ YF AY GL +T + + + QPALLYL
Sbjct: 263 LGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYL 322
Query: 478 VPCTLVTSCAVALWRRELGVFWTGSGFAKVLPPSP 512
VP + VAL + E+ ++ A++LP +P
Sbjct: 323 VPACIGFPVLVALAKGEVTEMFSYESSAEILPHTP 357
>gi|23308607 minor histocompatibility antigen 13 isoform 1 [Homo
sapiens]
Length = 377
Score = 85.5 bits (210), Expect = 1e-16
Identities = 62/198 (31%), Positives = 100/198 (50%), Gaps = 24/198 (12%)
Query: 302 LFCVAVSV---VWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLY 358
L C+ +S VW + R W+ + G+AF L ++ + L +LL LF+Y
Sbjct: 163 LVCLGLSSIVGVWYLLRKH----WIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIY 218
Query: 359 DIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLG 418
D+F+VF G+++MV VA + P+ L P+ + L F++LG
Sbjct: 219 DVFWVF--------GTNVMVTVAKS-------FEAPIKLVFPQ-DLLEKGLEANNFAMLG 262
Query: 419 FGDILVPGLLVAYCHRFDIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYL 477
GD+++PG+ +A RFDI ++ ++ YF AY GL +T + + + QPALLYL
Sbjct: 263 LGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYL 322
Query: 478 VPCTLVTSCAVALWRREL 495
VP + VAL + E+
Sbjct: 323 VPACIGFPVLVALAKGEV 340
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 43.9 bits (102), Expect = 4e-04
Identities = 26/79 (32%), Positives = 31/79 (39%)
Query: 505 AKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAP 564
AK+ PP PAP+ P P S +P P P P SP P P EE P
Sbjct: 399 AKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPP 458
Query: 565 MREPGSPAESEGRDQAQPS 583
P + + GR PS
Sbjct: 459 PVVPATCSRKRGRPPLTPS 477
Score = 35.4 bits (80), Expect = 0.15
Identities = 35/105 (33%), Positives = 45/105 (42%), Gaps = 13/105 (12%)
Query: 493 RELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSAT----PLSPQPPSEEPATSPWPAE 548
RE WT + LPP P AP P P PP AT PL + P P+ +
Sbjct: 605 REPTFRWTS--LTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIY 662
Query: 549 QSPKSRTSEEMGA-GAPMREP----GSPAESEGRDQAQPSPVTQP 588
+S T +GA AP EP SPAE E R + + ++ P
Sbjct: 663 ES--VLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLP 705
Score = 30.4 bits (67), Expect = 4.8
Identities = 21/80 (26%), Positives = 25/80 (31%), Gaps = 20/80 (25%)
Query: 509 PPSPWAPAPADGPQPP--------------------KDSATPLSPQPPSEEPATSPWPAE 548
PP P +P P P PP K PL+P +E A P
Sbjct: 432 PPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEG 491
Query: 549 QSPKSRTSEEMGAGAPMREP 568
SP + T G P P
Sbjct: 492 TSPPTPTPSTATGGPPEDSP 511
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQPPSEEPATS-PWPAEQSPK-----SRTSEEMGAGA 563
P P P PA P SA P S QP S +P P PA+ SP+ S++ G+
Sbjct: 479 PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
Query: 564 PMREPGSPAESEGRDQAQPSPVTQPGA 590
P + SPA+ Q PV+Q G+
Sbjct: 539 PSAQQPSPAKPSA--QQSTKPVSQTGS 563
Score = 38.1 bits (87), Expect = 0.023
Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 510 PSPWAPAPAD-GPQPPKDSATPLSPQPPSEEP-ATSPWPAEQSPKSRTS--EEMGAGAPM 565
P P P PA PQ P S P S QP S +P A P PA+ S + T + G+G P+
Sbjct: 509 PPPQQPGPAKPSPQQPG-STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Query: 566 REPG-SPAESEGRDQAQPSPV 585
+ P SP+ + Q P +
Sbjct: 568 QPPTVSPSAKQPPSQGLPKTI 588
Score = 35.0 bits (79), Expect = 0.19
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 6/81 (7%)
Query: 515 PAPADGPQPPKDSATPLSPQP-----PSEEPATSPWPAEQ-SPKSRTSEEMGAGAPMREP 568
P PA P P PL+ QP P + P T+ PA+ P +++ G+ P E
Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385
Query: 569 GSPAESEGRDQAQPSPVTQPG 589
P +P QPG
Sbjct: 386 PGPKALAQPPGVGKTPAQQPG 406
Score = 33.5 bits (75), Expect = 0.56
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 514 APAPADGPQPPKDSATPLSPQPPSEE----PATSPWPAEQSPKSRTSEEMGAGAPMREPG 569
+P P D PK S TP P+P + + P SP P EQS + + AP +P
Sbjct: 863 SPKP-DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921
Query: 570 SPAES 574
+P E+
Sbjct: 922 TPQET 926
Score = 33.1 bits (74), Expect = 0.74
Identities = 18/78 (23%), Positives = 33/78 (42%), Gaps = 3/78 (3%)
Query: 510 PSPWAPAPADGPQPPKD---SATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMR 566
P P +P P +D + P P P ++P P+ ++ + ++ + AP +
Sbjct: 677 PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736
Query: 567 EPGSPAESEGRDQAQPSP 584
EP P+E + A P
Sbjct: 737 EPSVPSEQDKAPVADDKP 754
Score = 32.7 bits (73), Expect = 0.96
Identities = 21/77 (27%), Positives = 30/77 (38%), Gaps = 1/77 (1%)
Query: 516 APADGP-QPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAES 574
A GP +PP P P P PA P S K + + P ++PG S
Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520
Query: 575 EGRDQAQPSPVTQPGAS 591
+ + P QPG++
Sbjct: 521 PQQPGSTKPPSQQPGSA 537
Score = 32.0 bits (71), Expect = 1.6
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 8/82 (9%)
Query: 515 PAPADGPQPPKDSATPLSPQPPSEEPATSPWPA-----EQSPKSRTSEEMGAGAPMREPG 569
P PA P + PL+ QP + PA +P P + P +++ G G +
Sbjct: 405 PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464
Query: 570 SPAE--SEGRDQAQPSPVTQPG 589
P + S+ A+P P QPG
Sbjct: 465 GPTKPPSQLPGPAKPPP-QQPG 485
Score = 31.6 bits (70), Expect = 2.1
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 8/80 (10%)
Query: 509 PPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRT-SEEMGAGAPMRE 567
PP P P P P PP P PP P TSP P K T + + P+ +
Sbjct: 2405 PPPPPPPPPPPPPPPP-------PPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFD 2457
Query: 568 PGSPAESEGRDQAQPSPVTQ 587
+ E+ ++ PVT+
Sbjct: 2458 AVTTLETTAVLRSNGLPVTR 2477
Score = 30.8 bits (68), Expect = 3.7
Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 10/89 (11%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQPPSEEPAT---SPWPAEQSP--KSRTSEEMGAGAP 564
PS P P QPP TP P++ P +P P Q P +S P
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
Query: 565 MREPGS---PAE--SEGRDQAQPSPVTQP 588
+++PG PA+ G+ AQ + T+P
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Score = 30.4 bits (67), Expect = 4.8
Identities = 21/87 (24%), Positives = 34/87 (39%), Gaps = 4/87 (4%)
Query: 506 KVLPPSPWAPAPADGP-QPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAP 564
K+ P P GP Q P+ L Q + P T + + S + P
Sbjct: 246 KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP 305
Query: 565 MREPGS---PAESEGRDQAQPSPVTQP 588
+++P PA+ G +++QP P P
Sbjct: 306 IQQPTPGKPPAQQPGHEKSQPGPAKPP 332
Score = 30.0 bits (66), Expect = 6.2
Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 8/83 (9%)
Query: 507 VLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMR 566
V P P PA P K SA P P P+ P PA+ P+ + A P +
Sbjct: 441 VQQPGP-GKIPAQQAGPGKTSAQQTGPTKP---PSQLPGPAKPPPQ----QPGPAKPPPQ 492
Query: 567 EPGSPAESEGRDQAQPSPVTQPG 589
+PGS + + P QPG
Sbjct: 493 QPGSAKPPSQQPGSTKPPPQQPG 515
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQPPSEEPATS-PWPAEQSPK-----SRTSEEMGAGA 563
P P P PA P SA P S QP S +P P PA+ SP+ S++ G+
Sbjct: 479 PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
Query: 564 PMREPGSPAESEGRDQAQPSPVTQPGA 590
P + SPA+ Q PV+Q G+
Sbjct: 539 PSAQQPSPAKPSA--QQSTKPVSQTGS 563
Score = 38.1 bits (87), Expect = 0.023
Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 510 PSPWAPAPAD-GPQPPKDSATPLSPQPPSEEP-ATSPWPAEQSPKSRTS--EEMGAGAPM 565
P P P PA PQ P S P S QP S +P A P PA+ S + T + G+G P+
Sbjct: 509 PPPQQPGPAKPSPQQPG-STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Query: 566 REPG-SPAESEGRDQAQPSPV 585
+ P SP+ + Q P +
Sbjct: 568 QPPTVSPSAKQPPSQGLPKTI 588
Score = 35.0 bits (79), Expect = 0.19
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 6/81 (7%)
Query: 515 PAPADGPQPPKDSATPLSPQP-----PSEEPATSPWPAEQ-SPKSRTSEEMGAGAPMREP 568
P PA P P PL+ QP P + P T+ PA+ P +++ G+ P E
Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385
Query: 569 GSPAESEGRDQAQPSPVTQPG 589
P +P QPG
Sbjct: 386 PGPKALAQPPGVGKTPAQQPG 406
Score = 33.5 bits (75), Expect = 0.56
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 514 APAPADGPQPPKDSATPLSPQPPSEE----PATSPWPAEQSPKSRTSEEMGAGAPMREPG 569
+P P D PK S TP P+P + + P SP P EQS + + AP +P
Sbjct: 863 SPKP-DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921
Query: 570 SPAES 574
+P E+
Sbjct: 922 TPQET 926
Score = 33.1 bits (74), Expect = 0.74
Identities = 18/78 (23%), Positives = 33/78 (42%), Gaps = 3/78 (3%)
Query: 510 PSPWAPAPADGPQPPKD---SATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMR 566
P P +P P +D + P P P ++P P+ ++ + ++ + AP +
Sbjct: 677 PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736
Query: 567 EPGSPAESEGRDQAQPSP 584
EP P+E + A P
Sbjct: 737 EPSVPSEQDKAPVADDKP 754
Score = 32.7 bits (73), Expect = 0.96
Identities = 21/77 (27%), Positives = 30/77 (38%), Gaps = 1/77 (1%)
Query: 516 APADGP-QPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAES 574
A GP +PP P P P PA P S K + + P ++PG S
Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520
Query: 575 EGRDQAQPSPVTQPGAS 591
+ + P QPG++
Sbjct: 521 PQQPGSTKPPSQQPGSA 537
Score = 32.0 bits (71), Expect = 1.6
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 8/82 (9%)
Query: 515 PAPADGPQPPKDSATPLSPQPPSEEPATSPWPA-----EQSPKSRTSEEMGAGAPMREPG 569
P PA P + PL+ QP + PA +P P + P +++ G G +
Sbjct: 405 PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464
Query: 570 SPAE--SEGRDQAQPSPVTQPG 589
P + S+ A+P P QPG
Sbjct: 465 GPTKPPSQLPGPAKPPP-QQPG 485
Score = 31.6 bits (70), Expect = 2.1
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 8/80 (10%)
Query: 509 PPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRT-SEEMGAGAPMRE 567
PP P P P P PP P PP P TSP P K T + + P+ +
Sbjct: 2405 PPPPPPPPPPPPPPPP-------PPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFD 2457
Query: 568 PGSPAESEGRDQAQPSPVTQ 587
+ E+ ++ PVT+
Sbjct: 2458 AVTTLETTAVLRSNGLPVTR 2477
Score = 30.8 bits (68), Expect = 3.7
Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 10/89 (11%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQPPSEEPAT---SPWPAEQSP--KSRTSEEMGAGAP 564
PS P P QPP TP P++ P +P P Q P +S P
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
Query: 565 MREPGS---PAE--SEGRDQAQPSPVTQP 588
+++PG PA+ G+ AQ + T+P
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Score = 30.4 bits (67), Expect = 4.8
Identities = 21/87 (24%), Positives = 34/87 (39%), Gaps = 4/87 (4%)
Query: 506 KVLPPSPWAPAPADGP-QPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAP 564
K+ P P GP Q P+ L Q + P T + + S + P
Sbjct: 246 KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP 305
Query: 565 MREPGS---PAESEGRDQAQPSPVTQP 588
+++P PA+ G +++QP P P
Sbjct: 306 IQQPTPGKPPAQQPGHEKSQPGPAKPP 332
Score = 30.0 bits (66), Expect = 6.2
Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 8/83 (9%)
Query: 507 VLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMR 566
V P P PA P K SA P P P+ P PA+ P+ + A P +
Sbjct: 441 VQQPGP-GKIPAQQAGPGKTSAQQTGPTKP---PSQLPGPAKPPPQ----QPGPAKPPPQ 492
Query: 567 EPGSPAESEGRDQAQPSPVTQPG 589
+PGS + + P QPG
Sbjct: 493 QPGSAKPPSQQPGSTKPPPQQPG 515
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 43.1 bits (100), Expect = 7e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Query: 501 GSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMG 560
GS A + +P P P GP P+ + PL P+ + EP + + EQ PK E G
Sbjct: 420 GSAGAPGIAGAPGFPGPR-GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG----EPG 474
Query: 561 AGAPMREPGSPAESEGRDQAQPSP 584
P PG PA EG+ A+ P
Sbjct: 475 PAGPQGAPG-PAGEEGKRGARGEP 497
Score = 30.8 bits (68), Expect = 3.7
Identities = 20/65 (30%), Positives = 22/65 (33%), Gaps = 2/65 (3%)
Query: 509 PPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKS--RTSEEMGAGAPMR 566
PP P A GP P P P PS + + P P S E G P
Sbjct: 1144 PPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1203
Query: 567 EPGSP 571
PG P
Sbjct: 1204 NPGPP 1208
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 43.1 bits (100), Expect = 7e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Query: 501 GSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMG 560
GS A + +P P P GP P+ + PL P+ + EP + + EQ PK E G
Sbjct: 351 GSAGAPGIAGAPGFPGPR-GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG----EPG 405
Query: 561 AGAPMREPGSPAESEGRDQAQPSP 584
P PG PA EG+ A+ P
Sbjct: 406 PAGPQGAPG-PAGEEGKRGARGEP 428
Score = 30.8 bits (68), Expect = 3.7
Identities = 20/65 (30%), Positives = 22/65 (33%), Gaps = 2/65 (3%)
Query: 509 PPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKS--RTSEEMGAGAPMR 566
PP P A GP P P P PS + + P P S E G P
Sbjct: 1075 PPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1134
Query: 567 EPGSP 571
PG P
Sbjct: 1135 NPGPP 1139
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/87 (33%), Positives = 33/87 (37%), Gaps = 10/87 (11%)
Query: 509 PPSPWAPAPADGPQPPKDSATPL----SPQP---PSEEPATSPWPAEQSPKSRTSEEMGA 561
PP PW P P P P A PL SP+P P E A P P S +
Sbjct: 26 PPPPWPPPP---PPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPT 82
Query: 562 GAPMREPGSPAESEGRDQAQPSPVTQP 588
P EP S E + P P T+P
Sbjct: 83 PEPATEPASEPAPEPATEPAPEPATEP 109
Score = 36.6 bits (83), Expect = 0.067
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 501 GSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPK--SRTSEE 558
G+ A+ P PA+ P+PP P P PP+ PA P +E SP+ E
Sbjct: 4 GAAAAQGTAPPQDGEQPAESPEPPPPWPPP--PPPPAPPPA-PPLLSEASPEPIPEPCPE 60
Query: 559 MGAGAPMREPGSPAESEGRDQAQPSPVTQPGA 590
+ G P E S + +E + P P T+P +
Sbjct: 61 LAPG-PCPEATSESATELYTEPTPEPATEPAS 91
Score = 36.6 bits (83), Expect = 0.067
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 25/101 (24%)
Query: 509 PPSPWAPAPAD------GPQPPKDSATPLSPQP---------------PSEEPATSPWPA 547
PP P AP PA P+P + L+P P P+ EPAT P +
Sbjct: 33 PPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEP-AS 91
Query: 548 EQSPKSRTSEEMGAGAPMREPGSPAESEGRDQAQPSPVTQP 588
E +P+ T A P EP E ++ P P +P
Sbjct: 92 EPAPEPATEP---APEPATEPAPEPAPEPATESAPEPTPEP 129
Score = 34.7 bits (78), Expect = 0.25
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQPPSEE-PATSPWPAEQSPKSRTSEEMGAGAPMREP 568
P+P PA +P + AT +P+P +E P +P PA +S T E P EP
Sbjct: 81 PTP-EPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVP--EP 137
Query: 569 GSPAESEGRDQAQPSPVTQP 588
E + P P +P
Sbjct: 138 APELTPEVAPELAPEPTPEP 157
Score = 30.0 bits (66), Expect = 6.2
Identities = 22/79 (27%), Positives = 31/79 (39%), Gaps = 15/79 (18%)
Query: 516 APADGPQPPKDSATPLSPQP-------PSEEPATSPWPAEQSPKSRTSEEMGAGAPMREP 568
AP P+ +SAT L +P P+ EPA P E +P+ T P EP
Sbjct: 62 APGPCPEATSESATELYTEPTPEPATEPASEPAPEP-ATEPAPEPATE-------PAPEP 113
Query: 569 GSPAESEGRDQAQPSPVTQ 587
+E + P P +
Sbjct: 114 APEPATESAPEPTPEPALE 132
Score = 29.6 bits (65), Expect = 8.2
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 11/81 (13%)
Query: 509 PPSPWAPAPADGPQPPKDSATPLSPQP-----PSEEPATSPWPAEQSPKSRTSEEMGAGA 563
P PAP P+P +SA +P+P P P +P A + T E + A
Sbjct: 103 PEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELA 162
Query: 564 PMREPGSPAESEGRDQAQPSP 584
P P E + +PSP
Sbjct: 163 PEFCP------EAAPEFRPSP 177
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 42.0 bits (97), Expect = 0.002
Identities = 35/90 (38%), Positives = 42/90 (46%), Gaps = 8/90 (8%)
Query: 507 VLPP---SPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGA 563
+LPP SP +P P + P P A+ LSP PP E PA SP P E SR EE
Sbjct: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSP-PPEELPA-SPLP-EALHLSRPLEESPLSP 496
Query: 564 PMREP--GSPAESEGRDQAQPSPVTQPGAS 591
P E P ES + SP++ P S
Sbjct: 497 PPEESPLSPPPESSPFSPLEESPLSPPEES 526
Score = 40.8 bits (94), Expect = 0.004
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 13/74 (17%)
Query: 509 PPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMREP 568
PPSP AP+PA PP + L +P +E P SP P SP+S +P
Sbjct: 4917 PPSPLAPSPAS---PPTEPLVELPTEPLAEPPVPSPLPLASSPESARP----------KP 4963
Query: 569 GSPAESEGRDQAQP 582
+ EG D P
Sbjct: 4964 RARPPEEGEDSRPP 4977
Score = 40.0 bits (92), Expect = 0.006
Identities = 26/66 (39%), Positives = 35/66 (53%), Gaps = 6/66 (9%)
Query: 505 AKVLPP---SPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGA 561
+++ PP SP +P P + P P A+ LSP PP + P TSP P E SP S E+
Sbjct: 660 SRLSPPPEESPLSPPPEESPTSPPPEASRLSP-PPEDSP-TSP-PPEDSPASPPPEDSLM 716
Query: 562 GAPMRE 567
P+ E
Sbjct: 717 SLPLEE 722
Score = 38.9 bits (89), Expect = 0.013
Identities = 30/91 (32%), Positives = 39/91 (42%), Gaps = 14/91 (15%)
Query: 505 AKVLPP---SPWAPAPADGPQPPKDSATPLSP-------QPPSEEPATSPWPAEQSPKSR 554
+++ PP SP +P P + P P + LSP PP EE SP P E+SP S
Sbjct: 624 SRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP-PPEESPTSP 682
Query: 555 TSEEMGAGAPMRE-PGSPAESEGRDQAQPSP 584
E P + P SP + A P P
Sbjct: 683 PPEASRLSPPPEDSPTSPPPED--SPASPPP 711
Score = 38.1 bits (87), Expect = 0.023
Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 10/78 (12%)
Query: 505 AKVLPPSPWAPAPADGPQPPKDSATPLSP------QPPSEEPATSPWPAEQSPKSRTSEE 558
++ L SP +P P + P P ++P SP PP E P P PA ++P S E
Sbjct: 486 SRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESP---PSPALETPLSPPPEA 542
Query: 559 MGAGAPMRE-PGSPAESE 575
P E P SP E
Sbjct: 543 SPLSPPFEESPLSPPPEE 560
Score = 38.1 bits (87), Expect = 0.023
Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 14/91 (15%)
Query: 509 PP--SPWAPAPADGPQPPKDSA------TPLSPQPPSEEPATSPWPAEQSPKSRTSEEMG 560
PP SP++P PP++S TPLSP PP P + P+ E+SP S EE+
Sbjct: 506 PPESSPFSPLEESPLSPPEESPPSPALETPLSP-PPEASPLSPPF--EESPLSPPPEELP 562
Query: 561 AGAP---MREPGSPAESEGRDQAQPSPVTQP 588
P R P ES + SP++ P
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPP 593
Score = 37.4 bits (85), Expect = 0.039
Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 11/79 (13%)
Query: 511 SPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMRE-PG 569
SP +P P + P P A+ LSP PP E P + P E+SP S E P E P
Sbjct: 552 SPLSPPPEELPTSPPPEASRLSP-PPEESPMSPP--PEESPMSPPPEASRLFPPFEESPL 608
Query: 570 SPAESEGRDQAQPSPVTQP 588
SP E SP++ P
Sbjct: 609 SPPPEE-------SPLSPP 620
Score = 37.0 bits (84), Expect = 0.051
Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 6/84 (7%)
Query: 514 APAPADGPQPPKDSATPLSPQP--PSEEPATSPWPAEQS---PKSRTSEEMGAGAP-MRE 567
+P P + P+ PLSP+P P EEP P P E P S G P + E
Sbjct: 843 SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE 902
Query: 568 PGSPAESEGRDQAQPSPVTQPGAS 591
PG P S ++ SP +P S
Sbjct: 903 PGEPPLSPLPEELPLSPSGEPSLS 926
Score = 36.6 bits (83), Expect = 0.067
Identities = 24/87 (27%), Positives = 34/87 (39%), Gaps = 3/87 (3%)
Query: 505 AKVLPP---SPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGA 561
+++ PP SP +P P + P P A+ LSP P + P + SP S
Sbjct: 597 SRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPL 656
Query: 562 GAPMREPGSPAESEGRDQAQPSPVTQP 588
R P ES + SP + P
Sbjct: 657 PVVSRLSPPPEESPLSPPPEESPTSPP 683
Score = 35.4 bits (80), Expect = 0.15
Identities = 29/89 (32%), Positives = 36/89 (40%), Gaps = 11/89 (12%)
Query: 508 LPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSP-------WPAEQSPKSRTSEEMG 560
L P AP + P P +PLSP PP E P + P P E+ P S E +
Sbjct: 426 LEPQLEAPLNEEMPLLPPPEESPLSP-PPEESPTSPPPEASRLSPPPEELPASPLPEALH 484
Query: 561 AGAPMRE-PGSPAESEGRDQAQPSPVTQP 588
P+ E P SP E P P + P
Sbjct: 485 LSRPLEESPLSPPPEE--SPLSPPPESSP 511
Score = 35.0 bits (79), Expect = 0.19
Identities = 32/106 (30%), Positives = 42/106 (39%), Gaps = 23/106 (21%)
Query: 505 AKVLPP---SPWAPAPADGPQPPKDSAT---------PLSPQPPSEEPATSP-------W 545
+++ PP SP +P P + P P A+ PLSP PP E P + P
Sbjct: 570 SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSP-PPEESPLSPPPEASRLSP 628
Query: 546 PAEQSPKSRTSEEMGAGAP---MREPGSPAESEGRDQAQPSPVTQP 588
P E SP S EE P R P S + SP++ P
Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
Score = 34.3 bits (77), Expect = 0.33
Identities = 29/93 (31%), Positives = 36/93 (38%), Gaps = 15/93 (16%)
Query: 509 PP--SPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPA--------EQSPKSRTSEE 558
PP S +P P D P P +P+SP P E SP P E+SP S EE
Sbjct: 620 PPEASRLSPPPEDSPMSPPPEESPMSPPP--EVSRLSPLPVVSRLSPPPEESPLSPPPEE 677
Query: 559 MGAGAP---MREPGSPAESEGRDQAQPSPVTQP 588
P R P +S + SP + P
Sbjct: 678 SPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP 710
Score = 33.9 bits (76), Expect = 0.43
Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 6/86 (6%)
Query: 508 LPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAE-----QSPKSRTSEEMGAG 562
LPP A P+ P A PL P+ P+ P P+P+ Q P S GAG
Sbjct: 2163 LPPQVPAQVPSQDPFGLAP-AYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAG 2221
Query: 563 APMREPGSPAESEGRDQAQPSPVTQP 588
P +P + + P P +P
Sbjct: 2222 QPGEFHTTPPGTPRHQPSTPDPFLKP 2247
Score = 33.5 bits (75), Expect = 0.56
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 12/92 (13%)
Query: 508 LPPSPWAPAPADGPQPPKDSATPLSPQPPSEE-----PAT----SPWPAEQSPKSRTSEE 558
LP P++ PA PQ S +PL+P+P S E P T SP P + P S +
Sbjct: 2403 LPSDPFSRVPAS-PQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRD 2461
Query: 559 MGAGAPMREPGSPAESEGRDQAQPSPVTQPGA 590
AP+ +P P E +A T GA
Sbjct: 2462 --PFAPLHKPPRPQPPEVAFKAGSLAHTSLGA 2491
Score = 31.2 bits (69), Expect = 2.8
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 10/77 (12%)
Query: 508 LPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWP--------AEQSPKSRTSEEM 559
L SP P P + P+ LSP+P EEP SP P AE+ S EE
Sbjct: 720 LEESPLLPLPEEPQLCPRSEGPHLSPRP--EEPHLSPRPEEPHLSPQAEEPHLSPQPEEP 777
Query: 560 GAGAPMREPGSPAESEG 576
A EP ++EG
Sbjct: 778 CLCAVPEEPHLSPQAEG 794
Score = 31.2 bits (69), Expect = 2.8
Identities = 35/146 (23%), Positives = 50/146 (34%), Gaps = 27/146 (18%)
Query: 467 MQRGQPALLYLVPCTLVTSCAVALWRR-------ELGVFWTGSGFAKVLPPSPWAPAPAD 519
+Q+ Q L T TS A+ R ELG GS A + P P
Sbjct: 2810 LQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVP 2869
Query: 520 GPQPPKD--------------SATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMG----A 561
GP P TP Q P + P +P + P E + +
Sbjct: 2870 GPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRF--YPVSEDPHRLAPEGLRGLAVS 2927
Query: 562 GAPMREPGSPAESEGRDQAQPSPVTQ 587
G P ++P +P E + P+P T+
Sbjct: 2928 GLPPQKPSAPPAPELNNSLHPTPHTK 2953
Score = 31.2 bits (69), Expect = 2.8
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 5/59 (8%)
Query: 535 PPSEEPATSPWPAEQSPKSRTSEEMG--AGAPMREPGSPAE---SEGRDQAQPSPVTQP 588
PP EEP+ P P SP S +E + P+ EP P+ + + A+P P +P
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARP 4967
Score = 30.8 bits (68), Expect = 3.7
Identities = 37/138 (26%), Positives = 50/138 (36%), Gaps = 17/138 (12%)
Query: 463 ALALMQRGQPALLYLVPCTLVTSCAVALWRRELGVFWTGSGFAKVLPPSPWAPAPADGPQ 522
AL L QP L P + + G+ + GF K PP+ P GP
Sbjct: 2101 ALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLK--PPAGSVP----GPD 2154
Query: 523 PPKDSATPLSPQPPSEEPATSP------WPAE----QSPKSRTSEEMGAGAPMREPGSPA 572
P + L PQ P++ P+ P +P E +P + GAP + P A
Sbjct: 2155 SPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGA 2214
Query: 573 ESE-GRDQAQPSPVTQPG 589
S G Q T PG
Sbjct: 2215 SSRPGAGQPGEFHTTPPG 2232
Score = 30.4 bits (67), Expect = 4.8
Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 6/64 (9%)
Query: 514 APAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAE 573
+P P + P+ + LSPQ SEEP SP P E S S E+ P P E
Sbjct: 816 SPVPEEPCLSPQPEESHLSPQ--SEEPCLSPRPEE----SHLSPELEKPPLSPRPEKPPE 869
Query: 574 SEGR 577
G+
Sbjct: 870 EPGQ 873
Score = 30.4 bits (67), Expect = 4.8
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 2/75 (2%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMREPG 569
PSP + P + PP TP PQ P+ EP + + T G G P P
Sbjct: 4324 PSPSSQLPTEAQLPPTHPGTP-KPQGPTLEPPPGRVSPAAAQLADTLFSKGLG-PWDPPD 4381
Query: 570 SPAESEGRDQAQPSP 584
+ AE++ +Q+ P
Sbjct: 4382 NLAETQKPEQSSLVP 4396
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 5/85 (5%)
Query: 509 PPSPWAPAPADGPQPP--KDSATPLSPQPPSEEPATS-PWPAEQSPKSRTSEEMGAGAP- 564
PPS P P GP PP + P P PPS A+S P P +Q+ + T+ P
Sbjct: 484 PPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPP 543
Query: 565 -MREPGSPAESEGRDQAQPSPVTQP 588
++ + A S G Q Q +P P
Sbjct: 544 WQQQQAAAAASPGAPQMQGNPTMVP 568
Score = 30.0 bits (66), Expect = 6.2
Identities = 27/104 (25%), Positives = 35/104 (33%), Gaps = 7/104 (6%)
Query: 495 LGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQS---P 551
LG GSG ++ P P G PP P PP P PW +Q P
Sbjct: 451 LGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGP-LPPWQQQQQQPPP 509
Query: 552 KSRTSEEMGAGAPM---REPGSPAESEGRDQAQPSPVTQPGASA 592
S M + P+ + + S G P Q A+A
Sbjct: 510 PPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAA 553
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 5/85 (5%)
Query: 509 PPSPWAPAPADGPQPP--KDSATPLSPQPPSEEPATS-PWPAEQSPKSRTSEEMGAGAP- 564
PPS P P GP PP + P P PPS A+S P P +Q+ + T+ P
Sbjct: 484 PPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPP 543
Query: 565 -MREPGSPAESEGRDQAQPSPVTQP 588
++ + A S G Q Q +P P
Sbjct: 544 WQQQQAAAAASPGAPQMQGNPTMVP 568
Score = 30.0 bits (66), Expect = 6.2
Identities = 27/104 (25%), Positives = 35/104 (33%), Gaps = 7/104 (6%)
Query: 495 LGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQS---P 551
LG GSG ++ P P G PP P PP P PW +Q P
Sbjct: 451 LGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGP-LPPWQQQQQQPPP 509
Query: 552 KSRTSEEMGAGAPM---REPGSPAESEGRDQAQPSPVTQPGASA 592
S M + P+ + + S G P Q A+A
Sbjct: 510 PPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAA 553
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 9/80 (11%)
Query: 509 PPSPWAPAPADGPQPPKDSAT-PLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMRE 567
PP P PQ P S PL P PP + P PA Q P + TS+ A P +
Sbjct: 197 PPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPP-----PASQQPPAPTSQLQQAPQPQQH 251
Query: 568 PGSPAESEGRDQAQPSPVTQ 587
S ++Q QPSP Q
Sbjct: 252 ---QPHSHSQNQNQPSPTQQ 268
Score = 40.8 bits (94), Expect = 0.004
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 10/88 (11%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQPPSEEPAT-------SPWPAEQSPKSRTSEEMGAG 562
P P AP+ Q P P P P S++P +P P + P S S+
Sbjct: 205 PQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSH-SQNQNQP 263
Query: 563 APMREPGSPAE--SEGRDQAQPSPVTQP 588
+P ++ SP + S+ PSP+T P
Sbjct: 264 SPTQQSSSPPQKPSQSPGHGLPSPLTPP 291
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 42.0 bits (97), Expect = 0.002
Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 15/89 (16%)
Query: 514 APAPADGPQPPKDSATPLSPQPPSEEPATSP------------WPAEQSPKSRTSEEMGA 561
AP P PP + A PL P P E+P SP P + + S+E+
Sbjct: 539 APPSMQPPAPPAELAAPL-PSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKELSP 597
Query: 562 GAPMREPGSPAESEGRDQAQPSPVTQPGA 590
G+ + GSP S+G A P QPGA
Sbjct: 598 GSAQK--GSPGSSQGTACAGTQPGAQPGA 624
Score = 31.2 bits (69), Expect = 2.8
Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 5/92 (5%)
Query: 500 TGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQP---PSEEPATSPWPAEQSPKS--R 554
T + +K L P Q + T QP P P+ S PA+QSP + +
Sbjct: 587 TSTTKSKELSPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRK 646
Query: 555 TSEEMGAGAPMREPGSPAESEGRDQAQPSPVT 586
S+++ P G P + QPSPV+
Sbjct: 647 VSKKLAPIPPKVPFGQPGAMADQSAGQPSPVS 678
>gi|4557317 annexin A11 [Homo sapiens]
Length = 505
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/89 (33%), Positives = 35/89 (39%), Gaps = 13/89 (14%)
Query: 501 GSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMG 560
G+G+ V P P A P PP P PPS P+ P+P P
Sbjct: 79 GAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVP--------- 129
Query: 561 AGAPMREPGSPAESEGRDQAQPSPVTQPG 589
G PM PG + G QP PVT PG
Sbjct: 130 -GQPMPPPGQ--QPPGAYPGQP-PVTYPG 154
>gi|22165433 annexin A11 [Homo sapiens]
Length = 505
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/89 (33%), Positives = 35/89 (39%), Gaps = 13/89 (14%)
Query: 501 GSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMG 560
G+G+ V P P A P PP P PPS P+ P+P P
Sbjct: 79 GAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVP--------- 129
Query: 561 AGAPMREPGSPAESEGRDQAQPSPVTQPG 589
G PM PG + G QP PVT PG
Sbjct: 130 -GQPMPPPGQ--QPPGAYPGQP-PVTYPG 154
>gi|22165431 annexin A11 [Homo sapiens]
Length = 505
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/89 (33%), Positives = 35/89 (39%), Gaps = 13/89 (14%)
Query: 501 GSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMG 560
G+G+ V P P A P PP P PPS P+ P+P P
Sbjct: 79 GAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVP--------- 129
Query: 561 AGAPMREPGSPAESEGRDQAQPSPVTQPG 589
G PM PG + G QP PVT PG
Sbjct: 130 -GQPMPPPGQ--QPPGAYPGQP-PVTYPG 154
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 41.6 bits (96), Expect = 0.002
Identities = 28/76 (36%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 500 TGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEM 559
+G G PP P PA A GP A +P PP E PA P P S+
Sbjct: 237 SGGGGLSPEPPEPPPPA-AKGPGAHASGAAGTAPAPPGEPPA----PGTCDPAFYPSQRS 291
Query: 560 GAGAPMREPGSPAESE 575
GAG P PG PA+ +
Sbjct: 292 GAG-PQPRPGRPADKD 306
Score = 34.3 bits (77), Expect = 0.33
Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 1/47 (2%)
Query: 502 SGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAE 548
+G A PP P AP+P GP+PP + P + P A P P E
Sbjct: 479 AGTAGPAPPPP-APSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPPE 524
Score = 32.3 bits (72), Expect = 1.3
Identities = 32/98 (32%), Positives = 40/98 (40%), Gaps = 28/98 (28%)
Query: 502 SGFAKVLPP---SPWAPAPADGPQPPKDSATPLS---------------PQPPSEEPATS 543
S FA+ P SP APAPA P P +D A+ + P PP P+
Sbjct: 437 SAFARRSPDAVASPGAPAPA--PAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPR 494
Query: 544 PWPAEQSPKSRTSEEMGAGAPMREPGS---PAESEGRD 578
P P SP E G P EPG+ P+ EG +
Sbjct: 495 PGPRPPSP---AEEPATCGVP--EPGAAAGPSPPEGEE 527
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 41.2 bits (95), Expect = 0.003
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 14/76 (18%)
Query: 515 PAPADGPQPPKDSATPLSPQPPSE-EPATSPWPAEQSPKSRTSEEMGAGAPMREP----G 569
PAP + P P + + +P++P P E PA P E+SP S AP+R P G
Sbjct: 1089 PAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPS---------APLRPPEPPAG 1139
Query: 570 SPAESEGRDQAQPSPV 585
PA + D+ SP+
Sbjct: 1140 PPAPAPRPDERPSSPI 1155
Score = 33.5 bits (75), Expect = 0.56
Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 12/83 (14%)
Query: 509 PPSPWAPAPADGP-QPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMRE 567
P P +P P +PP+ A P +P P +E +SP P PK R R+
Sbjct: 1118 PAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKR-----------RK 1166
Query: 568 PGSPAESEGRDQAQPSPVTQPGA 590
S + E +P P T P A
Sbjct: 1167 TVSFSAIEVVPAPEPPPATPPQA 1189
Score = 30.4 bits (67), Expect = 4.8
Identities = 23/70 (32%), Positives = 28/70 (40%), Gaps = 15/70 (21%)
Query: 504 FAKVLPPSPWAPAPADGPQPPKDSATPLSPQP--------PS---EEPATSPWPAEQ--- 549
+ LPP P P D P ++ P P+P PS EE TSP PA
Sbjct: 409 YTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARS 468
Query: 550 -SPKSRTSEE 558
SP T+ E
Sbjct: 469 GSPAPETTNE 478
Score = 29.6 bits (65), Expect = 8.2
Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 519 DGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAESEG-R 577
D + + +A P + PP E P +P P E R + P +E SPA G
Sbjct: 1064 DEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQE-ASPARPAGPT 1122
Query: 578 DQAQPSPVTQP 588
+++ PS +P
Sbjct: 1123 EESPPSAPLRP 1133
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/90 (33%), Positives = 35/90 (38%), Gaps = 9/90 (10%)
Query: 509 PPSPWAPA-PADGPQPPKDSATPLSP-QPPSEEPATSPWPAEQS-------PKSRTSEEM 559
PP P APA PA P PP A+P S P +P S + E P +EE
Sbjct: 786 PPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEE 845
Query: 560 GAGAPMREPGSPAESEGRDQAQPSPVTQPG 589
G P P P R P P+ PG
Sbjct: 846 GVPRPRAPPEPPDPGAPRPPPDPGPLPLPG 875
Score = 32.7 bits (73), Expect = 0.96
Identities = 19/68 (27%), Positives = 25/68 (36%), Gaps = 4/68 (5%)
Query: 515 PAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAES 574
P P P PP+ L P PP P +P +P SR G + G P +
Sbjct: 1174 PPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRA----GGDTALSGDGDPPKP 1229
Query: 575 EGRDQAQP 582
E + P
Sbjct: 1230 ERKGPEMP 1237
Score = 32.7 bits (73), Expect = 0.96
Identities = 27/94 (28%), Positives = 34/94 (36%), Gaps = 5/94 (5%)
Query: 502 SGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSR---TSEE 558
S + LPP P P GP+ P A +P PAE+ + E+
Sbjct: 1258 SRLSLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEED 1317
Query: 559 MGAGAPMREPGSPAESEGRDQAQPSPVTQPGASA 592
A AP G GR +A P PV A A
Sbjct: 1318 EEAAAPGAAAG--PRGPGRARAAPVPVVVSSADA 1349
Score = 30.8 bits (68), Expect = 3.7
Identities = 38/118 (32%), Positives = 44/118 (37%), Gaps = 40/118 (33%)
Query: 508 LPPSPWAPAP---------ADGPQPPKDSATPLSPQPP-----SEEPATSPWPAEQSPKS 553
LP +P A AP A PQ P P P PP +PA SP P P +
Sbjct: 749 LPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDP----PSA 804
Query: 554 RTSEEMGAGAPMREPG----------SP---------AESEG--RDQAQPSPVTQPGA 590
S G +P +PG SP AE EG R +A P P PGA
Sbjct: 805 VASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEP-PDPGA 861
Score = 30.0 bits (66), Expect = 6.2
Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 12/60 (20%)
Query: 521 PQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAESEGRDQA 580
PQPP PL P P ++ P P P+ AP EPG+P G D A
Sbjct: 1172 PQPPPP---PLPPPPEAQPRRLEPAPPRARPEV---------APEGEPGAPDSRAGGDTA 1219
>gi|238859557 regulatory factor X1 [Homo sapiens]
Length = 979
Score = 40.8 bits (94), Expect = 0.004
Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 3/73 (4%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSP---KSRTSEEMGAGAPMR 566
P P P P PQPP+ +PQP SP P Q P K +E AP +
Sbjct: 27 PQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQSPQPQAQPPGGQKQYVTELPAVPAPSQ 86
Query: 567 EPGSPAESEGRDQ 579
G+P S Q
Sbjct: 87 PTGAPTPSPAPQQ 99
Score = 37.7 bits (86), Expect = 0.030
Identities = 32/87 (36%), Positives = 38/87 (43%), Gaps = 10/87 (11%)
Query: 509 PPS--PWAPAPADG-PQPPKDSATPLSPQPPSEEPATSPWPAE----QSPKSRTSEEMGA 561
PPS P AP A P PP A P PQPP+ A +P P QSP+ + G
Sbjct: 14 PPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPT--AAATPQPQYVTELQSPQPQAQPPGGQ 71
Query: 562 GAPMRE-PGSPAESEGRDQAQPSPVTQ 587
+ E P PA S+ PSP Q
Sbjct: 72 KQYVTELPAVPAPSQPTGAPTPSPAPQ 98
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 40.8 bits (94), Expect = 0.004
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 6/83 (7%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMG---AGAPMR 566
PSP PA + + P ++ P P +EPA SP ++P R + G A +P
Sbjct: 524 PSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP---SETPGPRPAGPAGDEPAESPSE 580
Query: 567 EPGSPAESEGRDQAQPSPVTQPG 589
PG RD+ SP PG
Sbjct: 581 TPGPSPAGPTRDEPAESPSETPG 603
Score = 37.4 bits (85), Expect = 0.039
Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 4/87 (4%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQP----PSEEPATSPWPAEQSPKSRTSEEMGAGAPM 565
P P PA + + P ++ P P P+E P+ +P P+ P E + P
Sbjct: 544 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG 603
Query: 566 REPGSPAESEGRDQAQPSPVTQPGASA 592
P PA E + +P +P A
Sbjct: 604 PRPAGPAGDEPAESPSETPGPRPAGPA 630
Score = 37.4 bits (85), Expect = 0.039
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 6/85 (7%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMG---AGAPMR 566
P P PA + + P ++ P P +EPA SP ++P R + G A +P
Sbjct: 564 PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESP---SETPGPRPAGPAGDEPAESPSE 620
Query: 567 EPGSPAESEGRDQAQPSPVTQPGAS 591
PG D+ SP PG S
Sbjct: 621 TPGPRPAGPAGDEPAESPSETPGPS 645
Score = 34.7 bits (78), Expect = 0.25
Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 5/78 (6%)
Query: 511 SPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMREPGS 570
+P +P+ GP P A P +P +E P+ +P P P E + P P
Sbjct: 514 TPGSPSETPGPSP----AGPAGDEP-AESPSETPGPRPAGPAGDEPAESPSETPGPRPAG 568
Query: 571 PAESEGRDQAQPSPVTQP 588
PA E + +P P
Sbjct: 569 PAGDEPAESPSETPGPSP 586
Score = 32.0 bits (71), Expect = 1.6
Identities = 18/70 (25%), Positives = 26/70 (37%), Gaps = 4/70 (5%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQP----PSEEPATSPWPAEQSPKSRTSEEMGAGAPM 565
PSP P + + P ++ P P P+E P+ +P P P E + P
Sbjct: 584 PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 643
Query: 566 REPGSPAESE 575
P P E
Sbjct: 644 PSPAGPTRDE 653
Score = 30.0 bits (66), Expect = 6.2
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 10/75 (13%)
Query: 519 DGPQPPKDSATPLSPQPPSEEPATSP-WPAEQSPKSRTSEEMGAGAPMREPGSPAESEGR 577
+G PK+ +P PSE P SP PA P SE G P PA E
Sbjct: 505 EGRTGPKEG----TPGSPSETPGPSPAGPAGDEPAESPSETPGP-----RPAGPAGDEPA 555
Query: 578 DQAQPSPVTQPGASA 592
+ +P +P A
Sbjct: 556 ESPSETPGPRPAGPA 570
>gi|239754991 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 209
Score = 40.8 bits (94), Expect = 0.004
Identities = 33/95 (34%), Positives = 39/95 (41%), Gaps = 4/95 (4%)
Query: 499 WTGSGFAKVLPPSPWA-PAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSE 557
+ GS V+ S W PA GP+P A P SP P E +P P S S
Sbjct: 105 FAGSPLDLVVSQSGWRLSTPAVGPRPAARRAAPSSPAVPREGQRAAP-PPRPSGTFAASA 163
Query: 558 EMGAGAPMREPGSPAESEGRDQAQPSPVTQPGASA 592
+ G R GSPA R P PV GAS+
Sbjct: 164 RLSPGLAGR--GSPARPGARASHPPGPVGVFGASS 196
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 40.8 bits (94), Expect = 0.004
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 6/85 (7%)
Query: 510 PSPWAPAPADGPQPPKDSATPLSPQP--PSEEPATSPWPAEQS---PKSRTSEEMGAGAP 564
P A P + QPP P+S P P+ +PA P+ + P++ EE AGAP
Sbjct: 280 PESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEE-AAGAP 338
Query: 565 MREPGSPAESEGRDQAQPSPVTQPG 589
+R G E D + +P PG
Sbjct: 339 VRGAGDTDEEGEEDAFEDAPRGSPG 363
Score = 32.3 bits (72), Expect = 1.3
Identities = 31/93 (33%), Positives = 35/93 (37%), Gaps = 11/93 (11%)
Query: 506 KVLPPSPWAPAPADG--PQPPKDSA--TPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGA 561
++LPP P P P G P PP A PL P P + P P P P GA
Sbjct: 906 EMLPPPP-PPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP--GA 962
Query: 562 GAPMREP----GSPAESEGRDQAQPSPVTQPGA 590
G P+ P G P P P PGA
Sbjct: 963 GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 995
Score = 29.6 bits (65), Expect = 8.2
Identities = 30/99 (30%), Positives = 33/99 (33%), Gaps = 19/99 (19%)
Query: 503 GFAKVLPPSPWAPA------PADG-PQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRT 555
G V PP P P P+ PQPP T + P PP P P P
Sbjct: 872 GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLP---- 927
Query: 556 SEEMGAG----APMREPGSPAESEGRDQAQPSPVTQPGA 590
GAG P+ G P A P P PGA
Sbjct: 928 ----GAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGA 962
>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 40.8 bits (94), Expect = 0.004
Identities = 29/70 (41%), Positives = 35/70 (50%), Gaps = 10/70 (14%)
Query: 520 GPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAESEGRDQ 579
GPQP QPP + PA +P P S S+TSE + + AP REP E E R
Sbjct: 188 GPQPQHS-------QPPPQPPAVTPEPVALS--SQTSEPVESEAPPREPMEAEEVEERAP 238
Query: 580 AQPSPVTQPG 589
AQ +P PG
Sbjct: 239 AQ-NPELTPG 247
Score = 29.6 bits (65), Expect = 8.2
Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 6/75 (8%)
Query: 495 LGVFWTGSGFAKVLPPS-----PWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQ 549
LG G+G + V P+ P PA G AT +P PP P P P +Q
Sbjct: 609 LGPAGPGAGGSGVASPTITVAMPGVPAFLQG-MTDFLQATQTAPPPPPPPPPPPPAPEQQ 667
Query: 550 SPKSRTSEEMGAGAP 564
+ S GAG+P
Sbjct: 668 TMPPPGSPSGGAGSP 682
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.139 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,866,532
Number of Sequences: 37866
Number of extensions: 1321726
Number of successful extensions: 19049
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 202
Number of HSP's successfully gapped in prelim test: 732
Number of HSP's that attempted gapping in prelim test: 12350
Number of HSP's gapped (non-prelim): 5256
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.