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Search of human proteins with 41054846
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41054846 armadillo repeat containing, X-linked 5 [Homo
sapiens]
(558 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41054846 armadillo repeat containing, X-linked 5 [Homo sapiens] 1108 0.0
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 220 3e-57
gi|216547715 basic helix-loop-helix domain containing, class B, ... 213 5e-55
gi|216547682 basic helix-loop-helix domain containing, class B, ... 213 5e-55
gi|216547672 basic helix-loop-helix domain containing, class B, ... 213 5e-55
gi|216547663 basic helix-loop-helix domain containing, class B, ... 213 5e-55
gi|216547655 basic helix-loop-helix domain containing, class B, ... 213 5e-55
gi|216547646 basic helix-loop-helix domain containing, class B, ... 213 5e-55
gi|216547639 basic helix-loop-helix domain containing, class B, ... 213 5e-55
gi|39930463 basic helix-loop-helix domain containing, class B, 9... 213 5e-55
gi|150378528 G protein-coupled receptor associated sorting prote... 197 3e-50
gi|150378489 G protein-coupled receptor associated sorting prote... 197 3e-50
gi|103472136 G protein-coupled receptor associated sorting prote... 197 3e-50
gi|51702248 G protein-coupled receptor associated sorting protei... 172 6e-43
gi|19923967 G protein-coupled receptor associated sorting protei... 172 6e-43
gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens] 153 3e-37
gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens] 153 3e-37
gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens] 153 3e-37
gi|7706143 armadillo repeat containing, X-linked 1 [Homo sapiens] 152 6e-37
gi|238776793 SVH protein isoform b [Homo sapiens] 141 1e-33
gi|31377663 SVH protein isoform a [Homo sapiens] 141 1e-33
gi|169165522 PREDICTED: similar to SVH protein isoform 1 [Homo s... 115 8e-26
gi|238776797 SVH protein isoform e [Homo sapiens] 114 2e-25
gi|7662162 ALEX2 protein [Homo sapiens] 114 2e-25
gi|29540562 ALEX2 protein [Homo sapiens] 114 2e-25
gi|169165931 PREDICTED: similar to SVH protein isoform 1 [Homo s... 114 3e-25
gi|113414573 PREDICTED: similar to SVH protein isoform 2 [Homo s... 114 3e-25
gi|169165524 PREDICTED: similar to SVH protein isoform 2 [Homo s... 80 4e-15
gi|113415138 PREDICTED: similar to SVH protein isoform 2 [Homo s... 79 1e-14
gi|169165133 PREDICTED: similar to SVH protein isoform 1 [Homo s... 79 1e-14
>gi|41054846 armadillo repeat containing, X-linked 5 [Homo sapiens]
Length = 558
Score = 1108 bits (2865), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 1 MVDSGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMT 60
MVDSGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMT
Sbjct: 1 MVDSGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMT 60
Query: 61 RTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTVT 120
RTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTVT
Sbjct: 61 RTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTVT 120
Query: 121 KSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEP 180
KSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEP
Sbjct: 121 KSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEP 180
Query: 181 SVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPTLTIKQKVIAWSRARYIVLVPVEGGEQ 240
SVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPTLTIKQKVIAWSRARYIVLVPVEGGEQ
Sbjct: 181 SVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPTLTIKQKVIAWSRARYIVLVPVEGGEQ 240
Query: 241 SLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHC 300
SLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHC
Sbjct: 241 SLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHC 300
Query: 301 KSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENL 360
KSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENL
Sbjct: 301 KSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENL 360
Query: 361 VNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHL 420
VNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHL
Sbjct: 361 VNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHL 420
Query: 421 SIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVA 480
SIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVA
Sbjct: 421 SIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVA 480
Query: 481 PFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLA 540
PFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLA
Sbjct: 481 PFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLA 540
Query: 541 EHSDPEVRDKVIRLILKL 558
EHSDPEVRDKVIRLILKL
Sbjct: 541 EHSDPEVRDKVIRLILKL 558
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 220 bits (560), Expect = 3e-57
Identities = 169/556 (30%), Positives = 277/556 (49%), Gaps = 57/556 (10%)
Query: 4 SGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTH 63
SG+ R+ A G G A A +A A A AE E+ A AG G +
Sbjct: 1883 SGSWIRSEEVAYMGSCVGAEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAG 1942
Query: 64 TVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTVTKSE 123
++ + A T VE++ E + T ++ + +S + +
Sbjct: 1943 VWSW-DGDATT---------------VESRLGAGEEAGVESWTLARNVGEDELSRESSPD 1986
Query: 124 VKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVG 183
++ E ++RS + + + R ++ S +S D +I F +G
Sbjct: 1987 IE-----EISLRSLFWAESENSNTFRSKSGKDASF--ESGAGDNTSIKDKFEAAGGVDIG 2039
Query: 184 SWFWPEEETSLQVYKPLPKIQEKPKPTHKPTLTIKQKVIAWSRARYIVLVPVEGGEQSLP 243
SWF E + + K PK K K + SR Y +VP G
Sbjct: 2040 SWFCAGNENTSED-KSAPKA--------------KAKKSSESRGIYPYMVPGAG------ 2078
Query: 244 PEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKSR 303
G+W ET + P E +KQ R EK P +C CK
Sbjct: 2079 -MGSWDGAMIWSETKFAHQSEASFPVED--------ESRKQTRTGEK--TRPWSCRCKHE 2127
Query: 304 GFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNN 363
+++P++ +KL+ ++++T+DP +HEIA + S Y ++ +++ +VG +IE+L+NN
Sbjct: 2128 A-NMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNN 2186
Query: 364 PNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIK 423
P AL+ +++ S ++E + ++Y++QVC+ ++ PLNS VQLAGL+L+ HL+I
Sbjct: 2187 PYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTIT 2246
Query: 424 FEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFN 483
E +++T+YI +FL LL GS +TK +VL + SKN + T++L+ A +SL+ F+
Sbjct: 2247 SEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFS 2306
Query: 484 KNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDL-AEH 542
K E+K NILN + +FENIN+ FK +AK FT++KF+K+ L +FQ K +KL+ L AE
Sbjct: 2307 KKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAEC 2366
Query: 543 SDPEVRDKVIRLILKL 558
+DPEV+++V LI KL
Sbjct: 2367 NDPEVKERVELLISKL 2382
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/116 (37%), Positives = 59/116 (50%), Gaps = 9/116 (7%)
Query: 7 EARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHT-- 64
EA + AEAG + A + K A VA+ E K E++TQ KA + T
Sbjct: 238 EAVTQTDAEAGKI--VKKEAVTQTKAKAWA-LVAKTEAKREAMTQTKAETHILAEKETEI 294
Query: 65 ----VTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRV 116
VT E +AV REV K+ T KT ++ ETKT+ L E V +T+S+A P + V
Sbjct: 295 NRVMVTQSETLAVPREVAKMGATNKTGIVDETKTRALEETVSVAKTQSEARPGATV 350
Score = 48.1 bits (113), Expect = 2e-05
Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 15/140 (10%)
Query: 2 VDSGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTR 61
V+ G E AR A ++ + A R N + +A AE E ++ES A G +
Sbjct: 163 VEIGAETGARSGPGAEVETKATAIAIHRANSQAKAMVGAEPETQSESKVVA----GTLVM 218
Query: 62 THTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPM-------S 114
T VT E A REV E T+T + + + ++ V QTK+KA +
Sbjct: 219 TEAVTLTEVKAKAREVAMKEAVTQT----DAEAGKIVKKEAVTQTKAKAWALVAKTEAKR 274
Query: 115 RVSTVTKSEVKVVAVIEANI 134
T TK+E ++A E I
Sbjct: 275 EAMTQTKAETHILAEKETEI 294
Score = 42.7 bits (99), Expect = 9e-04
Identities = 44/178 (24%), Positives = 75/178 (42%), Gaps = 18/178 (10%)
Query: 8 ARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELK----TESVTQAKAG----DGAM 59
+ A KAEAG GI G +V Q E + A+ K + +V +A+AG A
Sbjct: 1024 SNAISKAEAGA--GIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQ 1081
Query: 60 TRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTV 119
+ + E + R +K + T+ A+ IV ++ + +P +R ++
Sbjct: 1082 PQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSM 1141
Query: 120 TKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTG 177
+ SE + A EA YAK +A P E G ++ + + NI ++W G
Sbjct: 1142 STSEAEATAEDEA----YAKPEAEA----MPTSESEGGSGTQACRKTQPNIHDYYWNG 1191
Score = 39.7 bits (91), Expect = 0.007
Identities = 22/60 (36%), Positives = 32/60 (53%)
Query: 131 EANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVGSWFWPEE 190
EA I S+ + +KA+ SRPD ++E + +S +E ICS + S GSW EE
Sbjct: 1832 EAVIGSWCWTEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEE 1891
Score = 38.5 bits (88), Expect = 0.016
Identities = 20/55 (36%), Positives = 27/55 (49%)
Query: 140 SHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVGSWFWPEEETSL 194
S D+A GS ++ S + S E E N WF G E +GSW W EE+ +
Sbjct: 1793 SEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGSWCWTEEKADI 1847
Score = 37.7 bits (86), Expect = 0.028
Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 30 VNGKTQAEAVAEAELKTE------SVTQAKAGDGA--MTRTHTVTYREAMAVTREVIKVE 81
V ++Q A+ EAE+KT+ + T A++G GA T+ + A + + ++ E
Sbjct: 143 VGVQSQTLAINEAEIKTKPQVEIGAETGARSGPGAEVETKATAIAIHRANSQAKAMVGAE 202
Query: 82 DTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSH 141
T++ V T + E + + K+KA ++ VT+++ + +++ + K+
Sbjct: 203 PETQSESKVVAGTLVMTEAVTLTEVKAKAREVAMKEAVTQTDAEAGKIVKKEAVTQTKAK 262
Query: 142 DKANTGSRPDRRE 154
A +RE
Sbjct: 263 AWALVAKTEAKRE 275
Score = 32.3 bits (72), Expect = 1.2
Identities = 42/182 (23%), Positives = 76/182 (41%), Gaps = 22/182 (12%)
Query: 4 SGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESV--TQAKAGDG---- 57
S + + RG A + G A A + +Q EA+ +A K+ AK GDG
Sbjct: 506 SDAKVKNRGNPNAMTKAG----AKANLRANSQVEALPDARDKSRGNPNVMAKVGDGTDML 561
Query: 58 AMTRTHTVTYREAMAVTREVIKVEDTTKTR----VMVETKTKPLAER--SIVPQTKSKAM 111
+ T+ V +A ++ IKV T V+ K + +A+ +P T+ KA
Sbjct: 562 SCTQPQLVASVQADTLSDGKIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKAR 621
Query: 112 PMSRVSTVT--KSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEEN 169
++ T ++K +A +++ A +A SR D R + K+ + ++
Sbjct: 622 GKAKAKCKTGPGMDMKTCTQPQAGVKTPA----EALLDSRVDGRGNPNATSKAGTKADQR 677
Query: 170 IC 171
+C
Sbjct: 678 VC 679
>gi|216547715 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 213 bits (541), Expect = 5e-55
Identities = 169/553 (30%), Positives = 272/553 (49%), Gaps = 67/553 (12%)
Query: 26 ATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTK 85
A A+ K +A A AE + V + A A + T + +A+A + V +K
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAV------SK 63
Query: 86 TRVMVETKTKPLAERSIVPQTKSKAMP-------MSRVSTVTKSEVKVVAVI----EANI 134
+V+ ETK L+E P+T KAM S+ K+E A EA I
Sbjct: 64 NKVVAETKEGALSE----PKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATI 119
Query: 135 RS-----------YAKSHDKANTGSRPDRRE-ETSIGMK------SSDEDEENIC-SWFW 175
S ++ +DK G++ E E + G + +E+EEN+ +WFW
Sbjct: 120 NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179
Query: 176 TGEEPSVGSWFWPEEETSLQVYKPLP--KIQEKPKPTHKPTLTIKQKVIAWSRA------ 227
G++ S F P + ++ KP P +I EK +P +TI A + A
Sbjct: 180 EGDDTS----FDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRS 235
Query: 228 ---------RYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTL 278
YIVL E SLP T T +P+ + P QT+
Sbjct: 236 QAPSEASPPSYIVLASAEENACSLPVA---TACRPSRNTRSCSQPIPECRFDSDPCIQTI 292
Query: 279 AEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGIS 338
EI++QIR RE G P AC CK + ++ +EF+KLV+LLK T DP IH+IA + MG+
Sbjct: 293 DEIRRQIRIREVNGIKPFACPCKMECY-MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVH 351
Query: 339 PAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCK 398
+PF Q+ I++VG+ +IE+L++ P+ + + ++ S E + E ++ +CK
Sbjct: 352 NVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCK 410
Query: 399 GIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSC 458
+S PLNSP Q +GLK+LG L+ F HY++ +Y + LL+ G+ KT+ VLK+
Sbjct: 411 ETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLN 470
Query: 459 LSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFT 518
+S+N R++I+ K L++L FN+ E+KAN+++ + IF NI + K + + +
Sbjct: 471 MSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR-KGSIVVVDHLS 529
Query: 519 KSELISIFQEAKQ 531
+ L++IF+E K+
Sbjct: 530 YNTLMAIFREVKE 542
>gi|216547682 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 213 bits (541), Expect = 5e-55
Identities = 169/553 (30%), Positives = 272/553 (49%), Gaps = 67/553 (12%)
Query: 26 ATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTK 85
A A+ K +A A AE + V + A A + T + +A+A + V +K
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAV------SK 63
Query: 86 TRVMVETKTKPLAERSIVPQTKSKAMP-------MSRVSTVTKSEVKVVAVI----EANI 134
+V+ ETK L+E P+T KAM S+ K+E A EA I
Sbjct: 64 NKVVAETKEGALSE----PKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATI 119
Query: 135 RS-----------YAKSHDKANTGSRPDRRE-ETSIGMK------SSDEDEENIC-SWFW 175
S ++ +DK G++ E E + G + +E+EEN+ +WFW
Sbjct: 120 NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179
Query: 176 TGEEPSVGSWFWPEEETSLQVYKPLP--KIQEKPKPTHKPTLTIKQKVIAWSRA------ 227
G++ S F P + ++ KP P +I EK +P +TI A + A
Sbjct: 180 EGDDTS----FDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRS 235
Query: 228 ---------RYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTL 278
YIVL E SLP T T +P+ + P QT+
Sbjct: 236 QAPSEASPPSYIVLASAEENACSLPVA---TACRPSRNTRSCSQPIPECRFDSDPCIQTI 292
Query: 279 AEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGIS 338
EI++QIR RE G P AC CK + ++ +EF+KLV+LLK T DP IH+IA + MG+
Sbjct: 293 DEIRRQIRIREVNGIKPFACPCKMECY-MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVH 351
Query: 339 PAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCK 398
+PF Q+ I++VG+ +IE+L++ P+ + + ++ S E + E ++ +CK
Sbjct: 352 NVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCK 410
Query: 399 GIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSC 458
+S PLNSP Q +GLK+LG L+ F HY++ +Y + LL+ G+ KT+ VLK+
Sbjct: 411 ETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLN 470
Query: 459 LSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFT 518
+S+N R++I+ K L++L FN+ E+KAN+++ + IF NI + K + + +
Sbjct: 471 MSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR-KGSIVVVDHLS 529
Query: 519 KSELISIFQEAKQ 531
+ L++IF+E K+
Sbjct: 530 YNTLMAIFREVKE 542
>gi|216547672 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 213 bits (541), Expect = 5e-55
Identities = 169/553 (30%), Positives = 272/553 (49%), Gaps = 67/553 (12%)
Query: 26 ATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTK 85
A A+ K +A A AE + V + A A + T + +A+A + V +K
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAV------SK 63
Query: 86 TRVMVETKTKPLAERSIVPQTKSKAMP-------MSRVSTVTKSEVKVVAVI----EANI 134
+V+ ETK L+E P+T KAM S+ K+E A EA I
Sbjct: 64 NKVVAETKEGALSE----PKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATI 119
Query: 135 RS-----------YAKSHDKANTGSRPDRRE-ETSIGMK------SSDEDEENIC-SWFW 175
S ++ +DK G++ E E + G + +E+EEN+ +WFW
Sbjct: 120 NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179
Query: 176 TGEEPSVGSWFWPEEETSLQVYKPLP--KIQEKPKPTHKPTLTIKQKVIAWSRA------ 227
G++ S F P + ++ KP P +I EK +P +TI A + A
Sbjct: 180 EGDDTS----FDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRS 235
Query: 228 ---------RYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTL 278
YIVL E SLP T T +P+ + P QT+
Sbjct: 236 QAPSEASPPSYIVLASAEENACSLPVA---TACRPSRNTRSCSQPIPECRFDSDPCIQTI 292
Query: 279 AEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGIS 338
EI++QIR RE G P AC CK + ++ +EF+KLV+LLK T DP IH+IA + MG+
Sbjct: 293 DEIRRQIRIREVNGIKPFACPCKMECY-MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVH 351
Query: 339 PAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCK 398
+PF Q+ I++VG+ +IE+L++ P+ + + ++ S E + E ++ +CK
Sbjct: 352 NVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCK 410
Query: 399 GIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSC 458
+S PLNSP Q +GLK+LG L+ F HY++ +Y + LL+ G+ KT+ VLK+
Sbjct: 411 ETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLN 470
Query: 459 LSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFT 518
+S+N R++I+ K L++L FN+ E+KAN+++ + IF NI + K + + +
Sbjct: 471 MSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR-KGSIVVVDHLS 529
Query: 519 KSELISIFQEAKQ 531
+ L++IF+E K+
Sbjct: 530 YNTLMAIFREVKE 542
>gi|216547663 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 213 bits (541), Expect = 5e-55
Identities = 169/553 (30%), Positives = 272/553 (49%), Gaps = 67/553 (12%)
Query: 26 ATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTK 85
A A+ K +A A AE + V + A A + T + +A+A + V +K
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAV------SK 63
Query: 86 TRVMVETKTKPLAERSIVPQTKSKAMP-------MSRVSTVTKSEVKVVAVI----EANI 134
+V+ ETK L+E P+T KAM S+ K+E A EA I
Sbjct: 64 NKVVAETKEGALSE----PKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATI 119
Query: 135 RS-----------YAKSHDKANTGSRPDRRE-ETSIGMK------SSDEDEENIC-SWFW 175
S ++ +DK G++ E E + G + +E+EEN+ +WFW
Sbjct: 120 NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179
Query: 176 TGEEPSVGSWFWPEEETSLQVYKPLP--KIQEKPKPTHKPTLTIKQKVIAWSRA------ 227
G++ S F P + ++ KP P +I EK +P +TI A + A
Sbjct: 180 EGDDTS----FDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRS 235
Query: 228 ---------RYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTL 278
YIVL E SLP T T +P+ + P QT+
Sbjct: 236 QAPSEASPPSYIVLASAEENACSLPVA---TACRPSRNTRSCSQPIPECRFDSDPCIQTI 292
Query: 279 AEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGIS 338
EI++QIR RE G P AC CK + ++ +EF+KLV+LLK T DP IH+IA + MG+
Sbjct: 293 DEIRRQIRIREVNGIKPFACPCKMECY-MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVH 351
Query: 339 PAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCK 398
+PF Q+ I++VG+ +IE+L++ P+ + + ++ S E + E ++ +CK
Sbjct: 352 NVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCK 410
Query: 399 GIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSC 458
+S PLNSP Q +GLK+LG L+ F HY++ +Y + LL+ G+ KT+ VLK+
Sbjct: 411 ETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLN 470
Query: 459 LSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFT 518
+S+N R++I+ K L++L FN+ E+KAN+++ + IF NI + K + + +
Sbjct: 471 MSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR-KGSIVVVDHLS 529
Query: 519 KSELISIFQEAKQ 531
+ L++IF+E K+
Sbjct: 530 YNTLMAIFREVKE 542
>gi|216547655 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 213 bits (541), Expect = 5e-55
Identities = 169/553 (30%), Positives = 272/553 (49%), Gaps = 67/553 (12%)
Query: 26 ATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTK 85
A A+ K +A A AE + V + A A + T + +A+A + V +K
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAV------SK 63
Query: 86 TRVMVETKTKPLAERSIVPQTKSKAMP-------MSRVSTVTKSEVKVVAVI----EANI 134
+V+ ETK L+E P+T KAM S+ K+E A EA I
Sbjct: 64 NKVVAETKEGALSE----PKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATI 119
Query: 135 RS-----------YAKSHDKANTGSRPDRRE-ETSIGMK------SSDEDEENIC-SWFW 175
S ++ +DK G++ E E + G + +E+EEN+ +WFW
Sbjct: 120 NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179
Query: 176 TGEEPSVGSWFWPEEETSLQVYKPLP--KIQEKPKPTHKPTLTIKQKVIAWSRA------ 227
G++ S F P + ++ KP P +I EK +P +TI A + A
Sbjct: 180 EGDDTS----FDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRS 235
Query: 228 ---------RYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTL 278
YIVL E SLP T T +P+ + P QT+
Sbjct: 236 QAPSEASPPSYIVLASAEENACSLPVA---TACRPSRNTRSCSQPIPECRFDSDPCIQTI 292
Query: 279 AEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGIS 338
EI++QIR RE G P AC CK + ++ +EF+KLV+LLK T DP IH+IA + MG+
Sbjct: 293 DEIRRQIRIREVNGIKPFACPCKMECY-MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVH 351
Query: 339 PAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCK 398
+PF Q+ I++VG+ +IE+L++ P+ + + ++ S E + E ++ +CK
Sbjct: 352 NVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCK 410
Query: 399 GIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSC 458
+S PLNSP Q +GLK+LG L+ F HY++ +Y + LL+ G+ KT+ VLK+
Sbjct: 411 ETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLN 470
Query: 459 LSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFT 518
+S+N R++I+ K L++L FN+ E+KAN+++ + IF NI + K + + +
Sbjct: 471 MSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR-KGSIVVVDHLS 529
Query: 519 KSELISIFQEAKQ 531
+ L++IF+E K+
Sbjct: 530 YNTLMAIFREVKE 542
>gi|216547646 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 213 bits (541), Expect = 5e-55
Identities = 169/553 (30%), Positives = 272/553 (49%), Gaps = 67/553 (12%)
Query: 26 ATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTK 85
A A+ K +A A AE + V + A A + T + +A+A + V +K
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAV------SK 63
Query: 86 TRVMVETKTKPLAERSIVPQTKSKAMP-------MSRVSTVTKSEVKVVAVI----EANI 134
+V+ ETK L+E P+T KAM S+ K+E A EA I
Sbjct: 64 NKVVAETKEGALSE----PKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATI 119
Query: 135 RS-----------YAKSHDKANTGSRPDRRE-ETSIGMK------SSDEDEENIC-SWFW 175
S ++ +DK G++ E E + G + +E+EEN+ +WFW
Sbjct: 120 NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179
Query: 176 TGEEPSVGSWFWPEEETSLQVYKPLP--KIQEKPKPTHKPTLTIKQKVIAWSRA------ 227
G++ S F P + ++ KP P +I EK +P +TI A + A
Sbjct: 180 EGDDTS----FDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRS 235
Query: 228 ---------RYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTL 278
YIVL E SLP T T +P+ + P QT+
Sbjct: 236 QAPSEASPPSYIVLASAEENACSLPVA---TACRPSRNTRSCSQPIPECRFDSDPCIQTI 292
Query: 279 AEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGIS 338
EI++QIR RE G P AC CK + ++ +EF+KLV+LLK T DP IH+IA + MG+
Sbjct: 293 DEIRRQIRIREVNGIKPFACPCKMECY-MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVH 351
Query: 339 PAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCK 398
+PF Q+ I++VG+ +IE+L++ P+ + + ++ S E + E ++ +CK
Sbjct: 352 NVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCK 410
Query: 399 GIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSC 458
+S PLNSP Q +GLK+LG L+ F HY++ +Y + LL+ G+ KT+ VLK+
Sbjct: 411 ETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLN 470
Query: 459 LSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFT 518
+S+N R++I+ K L++L FN+ E+KAN+++ + IF NI + K + + +
Sbjct: 471 MSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR-KGSIVVVDHLS 529
Query: 519 KSELISIFQEAKQ 531
+ L++IF+E K+
Sbjct: 530 YNTLMAIFREVKE 542
>gi|216547639 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 213 bits (541), Expect = 5e-55
Identities = 169/553 (30%), Positives = 272/553 (49%), Gaps = 67/553 (12%)
Query: 26 ATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTK 85
A A+ K +A A AE + V + A A + T + +A+A + V +K
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAV------SK 63
Query: 86 TRVMVETKTKPLAERSIVPQTKSKAMP-------MSRVSTVTKSEVKVVAVI----EANI 134
+V+ ETK L+E P+T KAM S+ K+E A EA I
Sbjct: 64 NKVVAETKEGALSE----PKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATI 119
Query: 135 RS-----------YAKSHDKANTGSRPDRRE-ETSIGMK------SSDEDEENIC-SWFW 175
S ++ +DK G++ E E + G + +E+EEN+ +WFW
Sbjct: 120 NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179
Query: 176 TGEEPSVGSWFWPEEETSLQVYKPLP--KIQEKPKPTHKPTLTIKQKVIAWSRA------ 227
G++ S F P + ++ KP P +I EK +P +TI A + A
Sbjct: 180 EGDDTS----FDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRS 235
Query: 228 ---------RYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTL 278
YIVL E SLP T T +P+ + P QT+
Sbjct: 236 QAPSEASPPSYIVLASAEENACSLPVA---TACRPSRNTRSCSQPIPECRFDSDPCIQTI 292
Query: 279 AEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGIS 338
EI++QIR RE G P AC CK + ++ +EF+KLV+LLK T DP IH+IA + MG+
Sbjct: 293 DEIRRQIRIREVNGIKPFACPCKMECY-MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVH 351
Query: 339 PAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCK 398
+PF Q+ I++VG+ +IE+L++ P+ + + ++ S E + E ++ +CK
Sbjct: 352 NVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCK 410
Query: 399 GIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSC 458
+S PLNSP Q +GLK+LG L+ F HY++ +Y + LL+ G+ KT+ VLK+
Sbjct: 411 ETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLN 470
Query: 459 LSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFT 518
+S+N R++I+ K L++L FN+ E+KAN+++ + IF NI + K + + +
Sbjct: 471 MSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR-KGSIVVVDHLS 529
Query: 519 KSELISIFQEAKQ 531
+ L++IF+E K+
Sbjct: 530 YNTLMAIFREVKE 542
>gi|39930463 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 213 bits (541), Expect = 5e-55
Identities = 169/553 (30%), Positives = 272/553 (49%), Gaps = 67/553 (12%)
Query: 26 ATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTK 85
A A+ K +A A AE + V + A A + T + +A+A + V +K
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAV------SK 63
Query: 86 TRVMVETKTKPLAERSIVPQTKSKAMP-------MSRVSTVTKSEVKVVAVI----EANI 134
+V+ ETK L+E P+T KAM S+ K+E A EA I
Sbjct: 64 NKVVAETKEGALSE----PKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATI 119
Query: 135 RS-----------YAKSHDKANTGSRPDRRE-ETSIGMK------SSDEDEENIC-SWFW 175
S ++ +DK G++ E E + G + +E+EEN+ +WFW
Sbjct: 120 NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179
Query: 176 TGEEPSVGSWFWPEEETSLQVYKPLP--KIQEKPKPTHKPTLTIKQKVIAWSRA------ 227
G++ S F P + ++ KP P +I EK +P +TI A + A
Sbjct: 180 EGDDTS----FDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRS 235
Query: 228 ---------RYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTL 278
YIVL E SLP T T +P+ + P QT+
Sbjct: 236 QAPSEASPPSYIVLASAEENACSLPVA---TACRPSRNTRSCSQPIPECRFDSDPCIQTI 292
Query: 279 AEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGIS 338
EI++QIR RE G P AC CK + ++ +EF+KLV+LLK T DP IH+IA + MG+
Sbjct: 293 DEIRRQIRIREVNGIKPFACPCKMECY-MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVH 351
Query: 339 PAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCK 398
+PF Q+ I++VG+ +IE+L++ P+ + + ++ S E + E ++ +CK
Sbjct: 352 NVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCK 410
Query: 399 GIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSC 458
+S PLNSP Q +GLK+LG L+ F HY++ +Y + LL+ G+ KT+ VLK+
Sbjct: 411 ETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLN 470
Query: 459 LSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFT 518
+S+N R++I+ K L++L FN+ E+KAN+++ + IF NI + K + + +
Sbjct: 471 MSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR-KGSIVVVDHLS 529
Query: 519 KSELISIFQEAKQ 531
+ L++IF+E K+
Sbjct: 530 YNTLMAIFREVKE 542
>gi|150378528 G protein-coupled receptor associated sorting protein 1
[Homo sapiens]
Length = 1395
Score = 197 bits (500), Expect = 3e-50
Identities = 133/461 (28%), Positives = 242/461 (52%), Gaps = 35/461 (7%)
Query: 108 SKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKS-SDED 166
S+ + TV E K A + S+ ++ D+ + +R D ++ G ++ +DED
Sbjct: 943 SRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVD--NRTDNG--SNCGSRTLADED 998
Query: 167 EENICSWFWTGEEPSVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPT----LTIKQKVI 222
E + SWFW G+E S P + + ++++P P+ +P +T++ K
Sbjct: 999 EAIVGSWFWAGDEAHFESNPSPVFRA---ICRSTCSVEQEPDPSRRPQSWEEVTVQFKPG 1055
Query: 223 AWSRARYIVLVPVE-------------GGEQS---LPPEGNWTLVETLIETPLGIRPLTK 266
W R + + P GG+ L PEG E+L++ +P +
Sbjct: 1056 PWGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQ--ESLLQPD---QPSPE 1110
Query: 267 IPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPF 326
P + P Y+++ EI++ +R +E P +C+C + +EF++L+ L++ +DPF
Sbjct: 1111 FPFQYDPSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPF 1170
Query: 327 IHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEP 386
IHEI+ + MG+ A FT+D I D G+ +IE L+N P+ + L + +
Sbjct: 1171 IHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNL 1230
Query: 387 KSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSV 446
++YI +VC+ ++ ++SP QL+G++++ HL+ + H ++ +Y+ FL+LL G+
Sbjct: 1231 NIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNA 1290
Query: 447 KTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFK 506
KT+F+VLK+ LS+N T+EL+SA+ +S + FN+ E+ NI ++ IFENI K
Sbjct: 1291 KTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIK 1350
Query: 507 TKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEH-SDPE 546
K +F+ + F LIS F + ++F ++LQ ++ +DPE
Sbjct: 1351 -KETVFSDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPE 1390
Score = 44.3 bits (103), Expect = 3e-04
Identities = 41/145 (28%), Positives = 61/145 (42%), Gaps = 24/145 (16%)
Query: 50 TQAKAGDGAMTRTHTVTYREA----MAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQ 105
++ +AG A R REA M + +VIK E T ++P+ ++
Sbjct: 319 SKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKE---- 374
Query: 106 TKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGS------RPDRREETSIG 159
+R +TK E K A A + A+S ++A G+ +E SI
Sbjct: 375 --------ARARAMTKEEAKTKA--RARAKQEARSEEEALIGTWFWATDESSMADEASIE 424
Query: 160 MKSSDEDEENICSWFWTGEEPSVGS 184
EDE I SWFWT EE S+G+
Sbjct: 425 SSLQVEDESIIGSWFWTEEEASMGT 449
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 24/86 (27%)
Query: 152 RREETSIGMKSSDEDEENIC--SWFWTGE--------------------EPSVGSWFWPE 189
RRE S S +EE + SWFW E E +VGSWFWPE
Sbjct: 823 RREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPE 882
Query: 190 EETSLQVYKPLPKIQEKPKPTHKPTL 215
EE S+Q ++E T + T+
Sbjct: 883 EEASIQAGS--QAVEEMESETEEETI 906
Score = 42.0 bits (97), Expect = 0.001
Identities = 54/233 (23%), Positives = 90/233 (38%), Gaps = 53/233 (22%)
Query: 4 SGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAE------LKTESVTQAKAGDG 57
+G EA+ R K AG + A R + + EA + +K ES +
Sbjct: 311 AGKEAKFRSKMRAGKE------ANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENAN 364
Query: 58 AMTRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVS 117
+R A A+T+E KT+ K + +E + T A S ++
Sbjct: 365 TFSRPMIKKEARARAMTKE------EAKTKARARAKQEARSEEEALIGTWFWATDESSMA 418
Query: 118 TVTKSEVKVVAVIEANIRSYAKSHDKANTG------SRP------------DRREETSI- 158
E + E+ I S+ + ++A+ G SRP RE+TS+
Sbjct: 419 DEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMK 478
Query: 159 --------GMKSSDEDEENICSWFWTGEEPS--------VGSWFWPEEETSLQ 195
+ ++D+++ I SWFW GEE + GSWFW + S++
Sbjct: 479 TGAEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVE 531
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/196 (21%), Positives = 82/196 (41%), Gaps = 15/196 (7%)
Query: 8 ARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAK----AGDGAMTRTH 63
+R + +A+ Q ++ +Q +A + T+SV AK + D + T
Sbjct: 86 SRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTD 145
Query: 64 TVTYREAMAVTREVIKVEDTTKTRVMVETKT--KPLAERSIVPQTKSKAMPMSRVSTVTK 121
T ++ A + + +K + + +P +++ P + K + S VS++
Sbjct: 146 TESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDKS-VSSLFW 204
Query: 122 SEVKVVAV------IEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFW 175
S +V A ++ + RS ++ +ANT SR +E I S EDE WFW
Sbjct: 205 SGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFW 264
Query: 176 TGEEPSVGSWFWPEEE 191
++ +W P E+
Sbjct: 265 ARDK--TNTWSGPRED 278
Score = 37.0 bits (84), Expect = 0.048
Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 5/39 (12%)
Query: 161 KSSDEDEENIC-SWFW----TGEEPSVGSWFWPEEETSL 194
KS E+EE+I SWFW T E +GSW W EE+++
Sbjct: 694 KSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNI 732
Score = 35.4 bits (80), Expect = 0.14
Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 22/60 (36%)
Query: 155 ETSIGM----KSSDEDEENICSWFWTGEEPSV------------------GSWFWPEEET 192
E+ +G+ ++ E+EE I WFW+GE+ + GSWFW E +T
Sbjct: 531 ESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQT 590
Score = 32.0 bits (71), Expect = 1.5
Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 26/93 (27%)
Query: 120 TKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEE 179
T + K++ E I S+ D+A S REE+ + E+ + I SWFW GEE
Sbjct: 735 TGEKAKLLTEEETIINSWFWKEDEAI--SEATDREES----RPEAEEGDIIGSWFWAGEE 788
Query: 180 PS--------------------VGSWFWPEEET 192
VGSWF EET
Sbjct: 789 DRLEPAAETREEDRLAAEKEGIVGSWFGAREET 821
Score = 32.0 bits (71), Expect = 1.5
Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 20/51 (39%)
Query: 163 SDEDEENICSWFWTGEEPSV--------------------GSWFWPEEETS 193
++E+E + SWFW EE S+ GSWFW +E S
Sbjct: 868 TEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVS 918
Score = 30.4 bits (67), Expect = 4.5
Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 44/194 (22%)
Query: 37 EAVAEAELKTESVTQAKAGD--GAMTRTHTVTYREAMAVTREVIKV-------------- 80
EA++EA + ES +A+ GD G+ E A TRE ++
Sbjct: 758 EAISEATDREESRPEAEEGDIIGSWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGA 817
Query: 81 -EDTTKTRVMVETKTKPLAERSIVPQT----KSKAMPMSRVSTVTKSEVKVVAVIEANIR 135
E+T + +K+ P AE V + +A P + V+ V E +
Sbjct: 818 REETIRREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEA-VAGVGFESKPGTEEEEITVG 876
Query: 136 SYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPS-------------- 181
S+ ++A+ + EE M+S E+E SWFW G+E S
Sbjct: 877 SWFWPEEEASIQAGSQAVEE----MESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDD 932
Query: 182 ----VGSWFWPEEE 191
V SWFW ++
Sbjct: 933 EEMIVESWFWSRDK 946
Score = 29.6 bits (65), Expect = 7.6
Identities = 19/69 (27%), Positives = 23/69 (33%), Gaps = 33/69 (47%)
Query: 148 SRPDRREETSIGMKSSDEDEENICSWFWTG---------------------EEPSVGSWF 186
+RP EET G SWFW EEP +GSWF
Sbjct: 570 ARPGAEEETIFG------------SWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWF 617
Query: 187 WPEEETSLQ 195
W E ++
Sbjct: 618 WTRVEACVE 626
Score = 29.6 bits (65), Expect = 7.6
Identities = 16/49 (32%), Positives = 20/49 (40%), Gaps = 18/49 (36%)
Query: 165 EDEENICSWFWTGEEPS------------------VGSWFWPEEETSLQ 195
E+E I SWFW +E +GSWFW EE L+
Sbjct: 744 EEETIINSWFWKEDEAISEATDREESRPEAEEGDIIGSWFWAGEEDRLE 792
>gi|150378489 G protein-coupled receptor associated sorting protein 1
[Homo sapiens]
Length = 1395
Score = 197 bits (500), Expect = 3e-50
Identities = 133/461 (28%), Positives = 242/461 (52%), Gaps = 35/461 (7%)
Query: 108 SKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKS-SDED 166
S+ + TV E K A + S+ ++ D+ + +R D ++ G ++ +DED
Sbjct: 943 SRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVD--NRTDNG--SNCGSRTLADED 998
Query: 167 EENICSWFWTGEEPSVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPT----LTIKQKVI 222
E + SWFW G+E S P + + ++++P P+ +P +T++ K
Sbjct: 999 EAIVGSWFWAGDEAHFESNPSPVFRA---ICRSTCSVEQEPDPSRRPQSWEEVTVQFKPG 1055
Query: 223 AWSRARYIVLVPVE-------------GGEQS---LPPEGNWTLVETLIETPLGIRPLTK 266
W R + + P GG+ L PEG E+L++ +P +
Sbjct: 1056 PWGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQ--ESLLQPD---QPSPE 1110
Query: 267 IPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPF 326
P + P Y+++ EI++ +R +E P +C+C + +EF++L+ L++ +DPF
Sbjct: 1111 FPFQYDPSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPF 1170
Query: 327 IHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEP 386
IHEI+ + MG+ A FT+D I D G+ +IE L+N P+ + L + +
Sbjct: 1171 IHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNL 1230
Query: 387 KSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSV 446
++YI +VC+ ++ ++SP QL+G++++ HL+ + H ++ +Y+ FL+LL G+
Sbjct: 1231 NIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNA 1290
Query: 447 KTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFK 506
KT+F+VLK+ LS+N T+EL+SA+ +S + FN+ E+ NI ++ IFENI K
Sbjct: 1291 KTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIK 1350
Query: 507 TKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEH-SDPE 546
K +F+ + F LIS F + ++F ++LQ ++ +DPE
Sbjct: 1351 -KETVFSDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPE 1390
Score = 44.3 bits (103), Expect = 3e-04
Identities = 41/145 (28%), Positives = 61/145 (42%), Gaps = 24/145 (16%)
Query: 50 TQAKAGDGAMTRTHTVTYREA----MAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQ 105
++ +AG A R REA M + +VIK E T ++P+ ++
Sbjct: 319 SKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKE---- 374
Query: 106 TKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGS------RPDRREETSIG 159
+R +TK E K A A + A+S ++A G+ +E SI
Sbjct: 375 --------ARARAMTKEEAKTKA--RARAKQEARSEEEALIGTWFWATDESSMADEASIE 424
Query: 160 MKSSDEDEENICSWFWTGEEPSVGS 184
EDE I SWFWT EE S+G+
Sbjct: 425 SSLQVEDESIIGSWFWTEEEASMGT 449
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 24/86 (27%)
Query: 152 RREETSIGMKSSDEDEENIC--SWFWTGE--------------------EPSVGSWFWPE 189
RRE S S +EE + SWFW E E +VGSWFWPE
Sbjct: 823 RREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPE 882
Query: 190 EETSLQVYKPLPKIQEKPKPTHKPTL 215
EE S+Q ++E T + T+
Sbjct: 883 EEASIQAGS--QAVEEMESETEEETI 906
Score = 42.0 bits (97), Expect = 0.001
Identities = 54/233 (23%), Positives = 90/233 (38%), Gaps = 53/233 (22%)
Query: 4 SGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAE------LKTESVTQAKAGDG 57
+G EA+ R K AG + A R + + EA + +K ES +
Sbjct: 311 AGKEAKFRSKMRAGKE------ANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENAN 364
Query: 58 AMTRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVS 117
+R A A+T+E KT+ K + +E + T A S ++
Sbjct: 365 TFSRPMIKKEARARAMTKE------EAKTKARARAKQEARSEEEALIGTWFWATDESSMA 418
Query: 118 TVTKSEVKVVAVIEANIRSYAKSHDKANTG------SRP------------DRREETSI- 158
E + E+ I S+ + ++A+ G SRP RE+TS+
Sbjct: 419 DEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMK 478
Query: 159 --------GMKSSDEDEENICSWFWTGEEPS--------VGSWFWPEEETSLQ 195
+ ++D+++ I SWFW GEE + GSWFW + S++
Sbjct: 479 TGAEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVE 531
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/196 (21%), Positives = 82/196 (41%), Gaps = 15/196 (7%)
Query: 8 ARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAK----AGDGAMTRTH 63
+R + +A+ Q ++ +Q +A + T+SV AK + D + T
Sbjct: 86 SRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTD 145
Query: 64 TVTYREAMAVTREVIKVEDTTKTRVMVETKT--KPLAERSIVPQTKSKAMPMSRVSTVTK 121
T ++ A + + +K + + +P +++ P + K + S VS++
Sbjct: 146 TESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDKS-VSSLFW 204
Query: 122 SEVKVVAV------IEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFW 175
S +V A ++ + RS ++ +ANT SR +E I S EDE WFW
Sbjct: 205 SGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFW 264
Query: 176 TGEEPSVGSWFWPEEE 191
++ +W P E+
Sbjct: 265 ARDK--TNTWSGPRED 278
Score = 37.0 bits (84), Expect = 0.048
Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 5/39 (12%)
Query: 161 KSSDEDEENIC-SWFW----TGEEPSVGSWFWPEEETSL 194
KS E+EE+I SWFW T E +GSW W EE+++
Sbjct: 694 KSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNI 732
Score = 35.4 bits (80), Expect = 0.14
Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 22/60 (36%)
Query: 155 ETSIGM----KSSDEDEENICSWFWTGEEPSV------------------GSWFWPEEET 192
E+ +G+ ++ E+EE I WFW+GE+ + GSWFW E +T
Sbjct: 531 ESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQT 590
Score = 32.0 bits (71), Expect = 1.5
Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 26/93 (27%)
Query: 120 TKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEE 179
T + K++ E I S+ D+A S REE+ + E+ + I SWFW GEE
Sbjct: 735 TGEKAKLLTEEETIINSWFWKEDEAI--SEATDREES----RPEAEEGDIIGSWFWAGEE 788
Query: 180 PS--------------------VGSWFWPEEET 192
VGSWF EET
Sbjct: 789 DRLEPAAETREEDRLAAEKEGIVGSWFGAREET 821
Score = 32.0 bits (71), Expect = 1.5
Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 20/51 (39%)
Query: 163 SDEDEENICSWFWTGEEPSV--------------------GSWFWPEEETS 193
++E+E + SWFW EE S+ GSWFW +E S
Sbjct: 868 TEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVS 918
Score = 30.4 bits (67), Expect = 4.5
Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 44/194 (22%)
Query: 37 EAVAEAELKTESVTQAKAGD--GAMTRTHTVTYREAMAVTREVIKV-------------- 80
EA++EA + ES +A+ GD G+ E A TRE ++
Sbjct: 758 EAISEATDREESRPEAEEGDIIGSWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGA 817
Query: 81 -EDTTKTRVMVETKTKPLAERSIVPQT----KSKAMPMSRVSTVTKSEVKVVAVIEANIR 135
E+T + +K+ P AE V + +A P + V+ V E +
Sbjct: 818 REETIRREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEA-VAGVGFESKPGTEEEEITVG 876
Query: 136 SYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPS-------------- 181
S+ ++A+ + EE M+S E+E SWFW G+E S
Sbjct: 877 SWFWPEEEASIQAGSQAVEE----MESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDD 932
Query: 182 ----VGSWFWPEEE 191
V SWFW ++
Sbjct: 933 EEMIVESWFWSRDK 946
Score = 29.6 bits (65), Expect = 7.6
Identities = 19/69 (27%), Positives = 23/69 (33%), Gaps = 33/69 (47%)
Query: 148 SRPDRREETSIGMKSSDEDEENICSWFWTG---------------------EEPSVGSWF 186
+RP EET G SWFW EEP +GSWF
Sbjct: 570 ARPGAEEETIFG------------SWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWF 617
Query: 187 WPEEETSLQ 195
W E ++
Sbjct: 618 WTRVEACVE 626
Score = 29.6 bits (65), Expect = 7.6
Identities = 16/49 (32%), Positives = 20/49 (40%), Gaps = 18/49 (36%)
Query: 165 EDEENICSWFWTGEEPS------------------VGSWFWPEEETSLQ 195
E+E I SWFW +E +GSWFW EE L+
Sbjct: 744 EEETIINSWFWKEDEAISEATDREESRPEAEEGDIIGSWFWAGEEDRLE 792
>gi|103472136 G protein-coupled receptor associated sorting protein 1
[Homo sapiens]
Length = 1395
Score = 197 bits (500), Expect = 3e-50
Identities = 133/461 (28%), Positives = 242/461 (52%), Gaps = 35/461 (7%)
Query: 108 SKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKS-SDED 166
S+ + TV E K A + S+ ++ D+ + +R D ++ G ++ +DED
Sbjct: 943 SRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVD--NRTDNG--SNCGSRTLADED 998
Query: 167 EENICSWFWTGEEPSVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPT----LTIKQKVI 222
E + SWFW G+E S P + + ++++P P+ +P +T++ K
Sbjct: 999 EAIVGSWFWAGDEAHFESNPSPVFRA---ICRSTCSVEQEPDPSRRPQSWEEVTVQFKPG 1055
Query: 223 AWSRARYIVLVPVE-------------GGEQS---LPPEGNWTLVETLIETPLGIRPLTK 266
W R + + P GG+ L PEG E+L++ +P +
Sbjct: 1056 PWGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQ--ESLLQPD---QPSPE 1110
Query: 267 IPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPF 326
P + P Y+++ EI++ +R +E P +C+C + +EF++L+ L++ +DPF
Sbjct: 1111 FPFQYDPSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPF 1170
Query: 327 IHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEP 386
IHEI+ + MG+ A FT+D I D G+ +IE L+N P+ + L + +
Sbjct: 1171 IHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNL 1230
Query: 387 KSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSV 446
++YI +VC+ ++ ++SP QL+G++++ HL+ + H ++ +Y+ FL+LL G+
Sbjct: 1231 NIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNA 1290
Query: 447 KTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFK 506
KT+F+VLK+ LS+N T+EL+SA+ +S + FN+ E+ NI ++ IFENI K
Sbjct: 1291 KTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIK 1350
Query: 507 TKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEH-SDPE 546
K +F+ + F LIS F + ++F ++LQ ++ +DPE
Sbjct: 1351 -KETVFSDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPE 1390
Score = 44.3 bits (103), Expect = 3e-04
Identities = 41/145 (28%), Positives = 61/145 (42%), Gaps = 24/145 (16%)
Query: 50 TQAKAGDGAMTRTHTVTYREA----MAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQ 105
++ +AG A R REA M + +VIK E T ++P+ ++
Sbjct: 319 SKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKE---- 374
Query: 106 TKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGS------RPDRREETSIG 159
+R +TK E K A A + A+S ++A G+ +E SI
Sbjct: 375 --------ARARAMTKEEAKTKA--RARAKQEARSEEEALIGTWFWATDESSMADEASIE 424
Query: 160 MKSSDEDEENICSWFWTGEEPSVGS 184
EDE I SWFWT EE S+G+
Sbjct: 425 SSLQVEDESIIGSWFWTEEEASMGT 449
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 24/86 (27%)
Query: 152 RREETSIGMKSSDEDEENIC--SWFWTGE--------------------EPSVGSWFWPE 189
RRE S S +EE + SWFW E E +VGSWFWPE
Sbjct: 823 RREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPE 882
Query: 190 EETSLQVYKPLPKIQEKPKPTHKPTL 215
EE S+Q ++E T + T+
Sbjct: 883 EEASIQAGS--QAVEEMESETEEETI 906
Score = 42.0 bits (97), Expect = 0.001
Identities = 54/233 (23%), Positives = 90/233 (38%), Gaps = 53/233 (22%)
Query: 4 SGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAE------LKTESVTQAKAGDG 57
+G EA+ R K AG + A R + + EA + +K ES +
Sbjct: 311 AGKEAKFRSKMRAGKE------ANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENAN 364
Query: 58 AMTRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVS 117
+R A A+T+E KT+ K + +E + T A S ++
Sbjct: 365 TFSRPMIKKEARARAMTKE------EAKTKARARAKQEARSEEEALIGTWFWATDESSMA 418
Query: 118 TVTKSEVKVVAVIEANIRSYAKSHDKANTG------SRP------------DRREETSI- 158
E + E+ I S+ + ++A+ G SRP RE+TS+
Sbjct: 419 DEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMK 478
Query: 159 --------GMKSSDEDEENICSWFWTGEEPS--------VGSWFWPEEETSLQ 195
+ ++D+++ I SWFW GEE + GSWFW + S++
Sbjct: 479 TGAEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVE 531
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/196 (21%), Positives = 82/196 (41%), Gaps = 15/196 (7%)
Query: 8 ARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAK----AGDGAMTRTH 63
+R + +A+ Q ++ +Q +A + T+SV AK + D + T
Sbjct: 86 SRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTD 145
Query: 64 TVTYREAMAVTREVIKVEDTTKTRVMVETKT--KPLAERSIVPQTKSKAMPMSRVSTVTK 121
T ++ A + + +K + + +P +++ P + K + S VS++
Sbjct: 146 TESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDKS-VSSLFW 204
Query: 122 SEVKVVAV------IEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFW 175
S +V A ++ + RS ++ +ANT SR +E I S EDE WFW
Sbjct: 205 SGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFW 264
Query: 176 TGEEPSVGSWFWPEEE 191
++ +W P E+
Sbjct: 265 ARDK--TNTWSGPRED 278
Score = 37.0 bits (84), Expect = 0.048
Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 5/39 (12%)
Query: 161 KSSDEDEENIC-SWFW----TGEEPSVGSWFWPEEETSL 194
KS E+EE+I SWFW T E +GSW W EE+++
Sbjct: 694 KSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNI 732
Score = 35.4 bits (80), Expect = 0.14
Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 22/60 (36%)
Query: 155 ETSIGM----KSSDEDEENICSWFWTGEEPSV------------------GSWFWPEEET 192
E+ +G+ ++ E+EE I WFW+GE+ + GSWFW E +T
Sbjct: 531 ESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQT 590
Score = 32.0 bits (71), Expect = 1.5
Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 26/93 (27%)
Query: 120 TKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEE 179
T + K++ E I S+ D+A S REE+ + E+ + I SWFW GEE
Sbjct: 735 TGEKAKLLTEEETIINSWFWKEDEAI--SEATDREES----RPEAEEGDIIGSWFWAGEE 788
Query: 180 PS--------------------VGSWFWPEEET 192
VGSWF EET
Sbjct: 789 DRLEPAAETREEDRLAAEKEGIVGSWFGAREET 821
Score = 32.0 bits (71), Expect = 1.5
Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 20/51 (39%)
Query: 163 SDEDEENICSWFWTGEEPSV--------------------GSWFWPEEETS 193
++E+E + SWFW EE S+ GSWFW +E S
Sbjct: 868 TEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVS 918
Score = 30.4 bits (67), Expect = 4.5
Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 44/194 (22%)
Query: 37 EAVAEAELKTESVTQAKAGD--GAMTRTHTVTYREAMAVTREVIKV-------------- 80
EA++EA + ES +A+ GD G+ E A TRE ++
Sbjct: 758 EAISEATDREESRPEAEEGDIIGSWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGA 817
Query: 81 -EDTTKTRVMVETKTKPLAERSIVPQT----KSKAMPMSRVSTVTKSEVKVVAVIEANIR 135
E+T + +K+ P AE V + +A P + V+ V E +
Sbjct: 818 REETIRREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEA-VAGVGFESKPGTEEEEITVG 876
Query: 136 SYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPS-------------- 181
S+ ++A+ + EE M+S E+E SWFW G+E S
Sbjct: 877 SWFWPEEEASIQAGSQAVEE----MESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDD 932
Query: 182 ----VGSWFWPEEE 191
V SWFW ++
Sbjct: 933 EEMIVESWFWSRDK 946
Score = 29.6 bits (65), Expect = 7.6
Identities = 19/69 (27%), Positives = 23/69 (33%), Gaps = 33/69 (47%)
Query: 148 SRPDRREETSIGMKSSDEDEENICSWFWTG---------------------EEPSVGSWF 186
+RP EET G SWFW EEP +GSWF
Sbjct: 570 ARPGAEEETIFG------------SWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWF 617
Query: 187 WPEEETSLQ 195
W E ++
Sbjct: 618 WTRVEACVE 626
Score = 29.6 bits (65), Expect = 7.6
Identities = 16/49 (32%), Positives = 20/49 (40%), Gaps = 18/49 (36%)
Query: 165 EDEENICSWFWTGEEPS------------------VGSWFWPEEETSLQ 195
E+E I SWFW +E +GSWFW EE L+
Sbjct: 744 EEETIINSWFWKEDEAISEATDREESRPEAEEGDIIGSWFWAGEEDRLE 792
>gi|51702248 G protein-coupled receptor associated sorting protein 2
[Homo sapiens]
Length = 838
Score = 172 bits (437), Expect = 6e-43
Identities = 123/426 (28%), Positives = 212/426 (49%), Gaps = 36/426 (8%)
Query: 147 GSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVGSWFWPEEETSLQ-----VYKPLP 201
GS E++S+G + +E + + EE GSWFW +E VYK
Sbjct: 420 GSAYWAEEKSSLGAVAREEAKPE------SEEEAIFGSWFWDRDEACFDLNPCPVYKVSD 473
Query: 202 KIQE---------KPKPTHKPTLTIKQKVI--AWSRARYIVLVPVEGGEQ--------SL 242
+ ++ +P+ + T+ K + R+ +P E E L
Sbjct: 474 RFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLEL 533
Query: 243 PPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKS 302
PEG E+L++ +P + + P Y+++ EI++ +R RE +C C
Sbjct: 534 SPEGEEQ--ESLLQPD---QPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQ 588
Query: 303 RGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVN 362
+ +EF++ + L+ +DPFIHEI+ + MG+ A FT+D I D G+ +IE L+N
Sbjct: 589 CELKIGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLN 648
Query: 363 NPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSI 422
P+ + L + + E++I QVC+ ++ ++S QL G+++L HL++
Sbjct: 649 YPSSRVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTM 708
Query: 423 KFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPF 482
+ H +I +Y+ FL+LL + +TKF+VLK+ LS+N A ++L SAK LS V F
Sbjct: 709 TIDYHTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLF 768
Query: 483 NKNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQ-DLAE 541
N E+ NI +I++F+NI+ K+ + F+ LIS F+E ++ ++LQ +
Sbjct: 769 NIEETNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDN 828
Query: 542 HSDPEV 547
+DPEV
Sbjct: 829 QNDPEV 834
Score = 67.0 bits (162), Expect = 4e-11
Identities = 66/232 (28%), Positives = 96/232 (41%), Gaps = 25/232 (10%)
Query: 10 ARGKAEAGLQDGISGPATARVNG----KTQAEAVAEAELKTE--------SVTQAKAGDG 57
AR K EA G +V G KT+A+ + A KT+ S T AKA G
Sbjct: 60 ARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPG 119
Query: 58 AMTRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVS 117
A + + ++ T V + E ++T + PLA TKSK + M R
Sbjct: 120 ARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAW----PLATAESGSVTKSKGLSMDREL 175
Query: 118 TVTKSEVKVVAVIEANIRSYAKSHDKANTGS----RPDRREETSIGMKSSDEDEENICSW 173
+E + I+ + ++ N GS RP REE S DE + S
Sbjct: 176 VNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASS 235
Query: 174 FWTGEEPSVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPTLTIKQKVIAWS 225
FWTGEE SV S WP EE++ + + + + P +P + V +WS
Sbjct: 236 FWTGEETSVRS--WPREESNT---RSRHRAKHQTNPRSRPRSKQEAYVDSWS 282
Score = 44.3 bits (103), Expect = 3e-04
Identities = 45/205 (21%), Positives = 83/205 (40%), Gaps = 30/205 (14%)
Query: 4 SGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAK--------AG 55
+G + +A G + A K +A+A A++E TE+V+QA+ A
Sbjct: 94 TGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAW 153
Query: 56 DGAMTRTHTVTYREAMAVTREVIKVEDTT------------------KTRVMVETKTKPL 97
A + +VT + +++ RE++ V+ T +T + ++P
Sbjct: 154 PLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPR 213
Query: 98 AERSIVPQT----KSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRR 153
A ++ + S T ++ V+ E+N RS ++ + N SRP +
Sbjct: 214 AREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQTNPRSRPRSK 273
Query: 154 EETSIGMKSSDEDEENICSWFWTGE 178
+E + S EDE + FW GE
Sbjct: 274 QEAYVDSWSGSEDEASNPFSFWVGE 298
Score = 35.4 bits (80), Expect = 0.14
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 104 PQTKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMK-- 161
P+ + +A S++ T + + + E +S+ ++AN+ R +E+ + +K
Sbjct: 306 PRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNTALKLR 365
Query: 162 -SSDEDEENICSWFWTGEEPSVGSWFWPEEETSLQ 195
D D + + EE +GSWFW E+E SL+
Sbjct: 366 AQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLE 400
>gi|19923967 G protein-coupled receptor associated sorting protein 2
[Homo sapiens]
Length = 838
Score = 172 bits (437), Expect = 6e-43
Identities = 123/426 (28%), Positives = 212/426 (49%), Gaps = 36/426 (8%)
Query: 147 GSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVGSWFWPEEETSLQ-----VYKPLP 201
GS E++S+G + +E + + EE GSWFW +E VYK
Sbjct: 420 GSAYWAEEKSSLGAVAREEAKPE------SEEEAIFGSWFWDRDEACFDLNPCPVYKVSD 473
Query: 202 KIQE---------KPKPTHKPTLTIKQKVI--AWSRARYIVLVPVEGGEQ--------SL 242
+ ++ +P+ + T+ K + R+ +P E E L
Sbjct: 474 RFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLEL 533
Query: 243 PPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKS 302
PEG E+L++ +P + + P Y+++ EI++ +R RE +C C
Sbjct: 534 SPEGEEQ--ESLLQPD---QPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQ 588
Query: 303 RGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVN 362
+ +EF++ + L+ +DPFIHEI+ + MG+ A FT+D I D G+ +IE L+N
Sbjct: 589 CELKIGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLN 648
Query: 363 NPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSI 422
P+ + L + + E++I QVC+ ++ ++S QL G+++L HL++
Sbjct: 649 YPSSRVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTM 708
Query: 423 KFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPF 482
+ H +I +Y+ FL+LL + +TKF+VLK+ LS+N A ++L SAK LS V F
Sbjct: 709 TIDYHTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLF 768
Query: 483 NKNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQ-DLAE 541
N E+ NI +I++F+NI+ K+ + F+ LIS F+E ++ ++LQ +
Sbjct: 769 NIEETNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDN 828
Query: 542 HSDPEV 547
+DPEV
Sbjct: 829 QNDPEV 834
Score = 67.0 bits (162), Expect = 4e-11
Identities = 66/232 (28%), Positives = 96/232 (41%), Gaps = 25/232 (10%)
Query: 10 ARGKAEAGLQDGISGPATARVNG----KTQAEAVAEAELKTE--------SVTQAKAGDG 57
AR K EA G +V G KT+A+ + A KT+ S T AKA G
Sbjct: 60 ARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPG 119
Query: 58 AMTRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVS 117
A + + ++ T V + E ++T + PLA TKSK + M R
Sbjct: 120 ARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAW----PLATAESGSVTKSKGLSMDREL 175
Query: 118 TVTKSEVKVVAVIEANIRSYAKSHDKANTGS----RPDRREETSIGMKSSDEDEENICSW 173
+E + I+ + ++ N GS RP REE S DE + S
Sbjct: 176 VNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASS 235
Query: 174 FWTGEEPSVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPTLTIKQKVIAWS 225
FWTGEE SV S WP EE++ + + + + P +P + V +WS
Sbjct: 236 FWTGEETSVRS--WPREESNT---RSRHRAKHQTNPRSRPRSKQEAYVDSWS 282
Score = 44.3 bits (103), Expect = 3e-04
Identities = 45/205 (21%), Positives = 83/205 (40%), Gaps = 30/205 (14%)
Query: 4 SGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAK--------AG 55
+G + +A G + A K +A+A A++E TE+V+QA+ A
Sbjct: 94 TGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAW 153
Query: 56 DGAMTRTHTVTYREAMAVTREVIKVEDTT------------------KTRVMVETKTKPL 97
A + +VT + +++ RE++ V+ T +T + ++P
Sbjct: 154 PLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPR 213
Query: 98 AERSIVPQT----KSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRR 153
A ++ + S T ++ V+ E+N RS ++ + N SRP +
Sbjct: 214 AREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQTNPRSRPRSK 273
Query: 154 EETSIGMKSSDEDEENICSWFWTGE 178
+E + S EDE + FW GE
Sbjct: 274 QEAYVDSWSGSEDEASNPFSFWVGE 298
Score = 35.4 bits (80), Expect = 0.14
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 104 PQTKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMK-- 161
P+ + +A S++ T + + + E +S+ ++AN+ R +E+ + +K
Sbjct: 306 PRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNTALKLR 365
Query: 162 -SSDEDEENICSWFWTGEEPSVGSWFWPEEETSLQ 195
D D + + EE +GSWFW E+E SL+
Sbjct: 366 AQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLE 400
>gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens]
Length = 379
Score = 153 bits (387), Expect = 3e-37
Identities = 93/254 (36%), Positives = 155/254 (61%), Gaps = 4/254 (1%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVN--NP 364
L P+E K++ L+++++ P+I E A + +G + AY F +DII D+G ++ ++N +P
Sbjct: 118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDP 177
Query: 365 NVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKF 424
VKE AL ++++ S ++E + + Y++QVC I+ LNS VQLAGL+LL ++++
Sbjct: 178 IVKEK--ALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTN 235
Query: 425 EDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNK 484
E +++ + I DF L + G+ +TK VLK+ L++N A TREL+ A+V SSL + FNK
Sbjct: 236 EYQHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNK 295
Query: 485 NESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSD 544
E+K IL ++ IFENIN FK + T+ +F + L +E + K+ + H D
Sbjct: 296 KENKEVILKLLVIFENINDNFKWEENEPTQNQFGEGSLFFFLKEFQVCADKVLGIESHHD 355
Query: 545 PEVRDKVIRLILKL 558
V+ KV + + KL
Sbjct: 356 FLVKVKVGKFMAKL 369
>gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens]
Length = 379
Score = 153 bits (387), Expect = 3e-37
Identities = 93/254 (36%), Positives = 155/254 (61%), Gaps = 4/254 (1%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVN--NP 364
L P+E K++ L+++++ P+I E A + +G + AY F +DII D+G ++ ++N +P
Sbjct: 118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDP 177
Query: 365 NVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKF 424
VKE AL ++++ S ++E + + Y++QVC I+ LNS VQLAGL+LL ++++
Sbjct: 178 IVKEK--ALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTN 235
Query: 425 EDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNK 484
E +++ + I DF L + G+ +TK VLK+ L++N A TREL+ A+V SSL + FNK
Sbjct: 236 EYQHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNK 295
Query: 485 NESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSD 544
E+K IL ++ IFENIN FK + T+ +F + L +E + K+ + H D
Sbjct: 296 KENKEVILKLLVIFENINDNFKWEENEPTQNQFGEGSLFFFLKEFQVCADKVLGIESHHD 355
Query: 545 PEVRDKVIRLILKL 558
V+ KV + + KL
Sbjct: 356 FLVKVKVGKFMAKL 369
>gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens]
Length = 379
Score = 153 bits (387), Expect = 3e-37
Identities = 93/254 (36%), Positives = 155/254 (61%), Gaps = 4/254 (1%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVN--NP 364
L P+E K++ L+++++ P+I E A + +G + AY F +DII D+G ++ ++N +P
Sbjct: 118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDP 177
Query: 365 NVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKF 424
VKE AL ++++ S ++E + + Y++QVC I+ LNS VQLAGL+LL ++++
Sbjct: 178 IVKEK--ALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTN 235
Query: 425 EDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNK 484
E +++ + I DF L + G+ +TK VLK+ L++N A TREL+ A+V SSL + FNK
Sbjct: 236 EYQHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNK 295
Query: 485 NESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSD 544
E+K IL ++ IFENIN FK + T+ +F + L +E + K+ + H D
Sbjct: 296 KENKEVILKLLVIFENINDNFKWEENEPTQNQFGEGSLFFFLKEFQVCADKVLGIESHHD 355
Query: 545 PEVRDKVIRLILKL 558
V+ KV + + KL
Sbjct: 356 FLVKVKVGKFMAKL 369
>gi|7706143 armadillo repeat containing, X-linked 1 [Homo sapiens]
Length = 453
Score = 152 bits (385), Expect = 6e-37
Identities = 83/252 (32%), Positives = 150/252 (59%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNV 366
L + K++ +L+ T DPFI E+A + +G + AY F Q+ I ++G +I L+ +
Sbjct: 202 LSAPDLQKVLNILERTNDPFIQEVALVTLGNNAAYSFNQNAIRELGGVPIIAKLIKTKDP 261
Query: 367 KEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFED 426
+ +++ S ++E ++YI QVC + C L+S VQ+AGL+LL ++++
Sbjct: 262 IIREKTYNALNNLSVNAENQGKIKTYISQVCDDTMVCRLDSAVQMAGLRLLTNMTVTNHY 321
Query: 427 HYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNE 486
++++ PDF LL G+ TK ++K+ ++N A TREL+S KV S L++ FNK
Sbjct: 322 QHLLSYSFPDFFALLFLGNHFTKIQIMKLIINFTENPAMTRELVSCKVPSELISLFNKEW 381
Query: 487 SKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPE 546
+ +LNI+ +FENIN K + ++++F++S L +F+E+ +K++ LA H+D
Sbjct: 382 DREILLNILTLFENINDNIKNEGLASSRKEFSRSSLFFLFKESGVCVKKIKALANHNDLV 441
Query: 547 VRDKVIRLILKL 558
V+ KV++++ KL
Sbjct: 442 VKVKVLKVLTKL 453
>gi|238776793 SVH protein isoform b [Homo sapiens]
Length = 308
Score = 141 bits (356), Expect = 1e-33
Identities = 84/252 (33%), Positives = 146/252 (57%), Gaps = 1/252 (0%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNV 366
L ++ KL+ LL+ T+DP I E A + +G + A+ Q II ++G ++ N +N+ N
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 367 KEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFED 426
AL+ +++ S + E + YI QVC+ + S PLNS VQLAGL LL ++++ +
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 177
Query: 427 HYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNE 486
+++ SYI D +L G+ TK VLK+ LS+N A T L+ A+V SS ++ ++ +
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHV 237
Query: 487 SKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPE 546
+K +L ++ +F+NI K + L + FT+ L + ++ QK++ L +H D E
Sbjct: 238 AKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRALVDHHDAE 296
Query: 547 VRDKVIRLILKL 558
V++KV+ +I K+
Sbjct: 297 VKEKVVTIIPKI 308
>gi|31377663 SVH protein isoform a [Homo sapiens]
Length = 343
Score = 141 bits (356), Expect = 1e-33
Identities = 84/252 (33%), Positives = 146/252 (57%), Gaps = 1/252 (0%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNV 366
L ++ KL+ LL+ T+DP I E A + +G + A+ Q II ++G ++ N +N+ N
Sbjct: 93 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 152
Query: 367 KEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFED 426
AL+ +++ S + E + YI QVC+ + S PLNS VQLAGL LL ++++ +
Sbjct: 153 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 212
Query: 427 HYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNE 486
+++ SYI D +L G+ TK VLK+ LS+N A T L+ A+V SS ++ ++ +
Sbjct: 213 QHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHV 272
Query: 487 SKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPE 546
+K +L ++ +F+NI K + L + FT+ L + ++ QK++ L +H D E
Sbjct: 273 AKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRALVDHHDAE 331
Query: 547 VRDKVIRLILKL 558
V++KV+ +I K+
Sbjct: 332 VKEKVVTIIPKI 343
>gi|169165522 PREDICTED: similar to SVH protein isoform 1 [Homo
sapiens]
Length = 284
Score = 115 bits (289), Expect = 8e-26
Identities = 74/252 (29%), Positives = 133/252 (52%), Gaps = 25/252 (9%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNV 366
L ++ KL+ LL+ T+DP I E A + +G + A+ Q II ++G ++ N +N+ N
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 367 KEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFED 426
AL+ +++ S + E + YI QVC+ + S PLNS VQLAGL+LL ++++ +
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177
Query: 427 HYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNE 486
+++ SYI D +L G+ T KV SS ++ ++ +
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNT------------------------KVDSSFLSLYDSHV 213
Query: 487 SKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPE 546
+K +L ++ +F+NI K + L + FT+ L + ++ QK++ L +H D E
Sbjct: 214 AKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRALVDHHDAE 272
Query: 547 VRDKVIRLILKL 558
V++KV+ +I K+
Sbjct: 273 VKEKVVTIIPKI 284
>gi|238776797 SVH protein isoform e [Homo sapiens]
Length = 284
Score = 114 bits (286), Expect = 2e-25
Identities = 74/252 (29%), Positives = 132/252 (52%), Gaps = 25/252 (9%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNV 366
L ++ KL+ LL+ T+DP I E A + +G + A+ Q II ++G ++ N +N+ N
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 367 KEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFED 426
AL+ +++ S + E + YI QVC+ + S PLNS VQLAGL LL ++++ +
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 177
Query: 427 HYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNE 486
+++ SYI D +L G+ T KV SS ++ ++ +
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNT------------------------KVDSSFLSLYDSHV 213
Query: 487 SKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPE 546
+K +L ++ +F+NI K + L + FT+ L + ++ QK++ L +H D E
Sbjct: 214 AKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRALVDHHDAE 272
Query: 547 VRDKVIRLILKL 558
V++KV+ +I K+
Sbjct: 273 VKEKVVTIIPKI 284
>gi|7662162 ALEX2 protein [Homo sapiens]
Length = 632
Score = 114 bits (286), Expect = 2e-25
Identities = 78/277 (28%), Positives = 150/277 (54%), Gaps = 10/277 (3%)
Query: 287 QREKYGPNPKACHCKSRGFSLEP----KEFDKLVALLKLTKDPFIHEIATMIMGISPAYP 342
QR G P A + + ++ ++ K++ALL+ + DPFI ++A + + + Y
Sbjct: 359 QRRGRGRRPVAMQKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYS 418
Query: 343 FTQDIIHDVGITVMIENLVN--NPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGI 400
Q+ I +G +I N++N +P++KE AL +++ SE+ E + Y+++V I
Sbjct: 419 CNQETIRKLGGLPIIANMINKTDPHIKEK--ALMAMNNLSENYENQGRLQVYMNKVMDDI 476
Query: 401 ISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLS 460
++ LNS VQ+ GLK L +++I + +++ + I +F LL++G K K +LK+ S +
Sbjct: 477 MASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFA 536
Query: 461 KNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKS 520
+N ++L+S +V +S + +N ++N + +FE I +A++F +F K
Sbjct: 537 ENPDMLKKLLSTQVPASFSSLYNSYVESEILINALTLFEII--YDNLRAEVFNYREFNKG 594
Query: 521 ELISIFQEAKQFGQKLQDLAEHSDPEVRDKVIRLILK 557
L + + +K++ LA H D V+ KVI+L+ K
Sbjct: 595 SLFYLCTTSGVCVKKIRALANHHDLLVKVKVIKLVNK 631
>gi|29540562 ALEX2 protein [Homo sapiens]
Length = 632
Score = 114 bits (286), Expect = 2e-25
Identities = 78/277 (28%), Positives = 150/277 (54%), Gaps = 10/277 (3%)
Query: 287 QREKYGPNPKACHCKSRGFSLEP----KEFDKLVALLKLTKDPFIHEIATMIMGISPAYP 342
QR G P A + + ++ ++ K++ALL+ + DPFI ++A + + + Y
Sbjct: 359 QRRGRGRRPVAMQKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYS 418
Query: 343 FTQDIIHDVGITVMIENLVN--NPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGI 400
Q+ I +G +I N++N +P++KE AL +++ SE+ E + Y+++V I
Sbjct: 419 CNQETIRKLGGLPIIANMINKTDPHIKEK--ALMAMNNLSENYENQGRLQVYMNKVMDDI 476
Query: 401 ISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLS 460
++ LNS VQ+ GLK L +++I + +++ + I +F LL++G K K +LK+ S +
Sbjct: 477 MASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFA 536
Query: 461 KNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKS 520
+N ++L+S +V +S + +N ++N + +FE I +A++F +F K
Sbjct: 537 ENPDMLKKLLSTQVPASFSSLYNSYVESEILINALTLFEII--YDNLRAEVFNYREFNKG 594
Query: 521 ELISIFQEAKQFGQKLQDLAEHSDPEVRDKVIRLILK 557
L + + +K++ LA H D V+ KVI+L+ K
Sbjct: 595 SLFYLCTTSGVCVKKIRALANHHDLLVKVKVIKLVNK 631
>gi|169165931 PREDICTED: similar to SVH protein isoform 1 [Homo
sapiens]
Length = 284
Score = 114 bits (284), Expect = 3e-25
Identities = 73/252 (28%), Positives = 133/252 (52%), Gaps = 25/252 (9%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNV 366
L ++ KL+ LL+ T+DP I E A + +G + A+ Q II ++G ++ N +N+ N
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 367 KEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFED 426
AL+ +++ S + E + YI QVC+ + S PLNS VQLAGL+LL ++++ +
Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177
Query: 427 HYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNE 486
+++ SYI D +L G+ T KV SS ++ ++ +
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNT------------------------KVDSSFLSLYDSHV 213
Query: 487 SKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPE 546
+K +L ++ +F++I K + L + FT+ L + ++ QK++ L +H D E
Sbjct: 214 AKEILLRVLTLFQHIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRALVDHHDAE 272
Query: 547 VRDKVIRLILKL 558
V++KV+ +I K+
Sbjct: 273 VKEKVVTIIPKI 284
>gi|113414573 PREDICTED: similar to SVH protein isoform 2 [Homo
sapiens]
Length = 284
Score = 114 bits (284), Expect = 3e-25
Identities = 73/252 (28%), Positives = 133/252 (52%), Gaps = 25/252 (9%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNV 366
L ++ KL+ LL+ T+DP I E A + +G + A+ Q II ++G ++ N +N+ N
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 367 KEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFED 426
AL+ +++ S + E + YI QVC+ + S PLNS VQLAGL+LL ++++ +
Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177
Query: 427 HYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNE 486
+++ SYI D +L G+ T KV SS ++ ++ +
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNT------------------------KVDSSFLSLYDSHV 213
Query: 487 SKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPE 546
+K +L ++ +F++I K + L + FT+ L + ++ QK++ L +H D E
Sbjct: 214 AKEILLRVLTLFQHIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRALVDHHDAE 272
Query: 547 VRDKVIRLILKL 558
V++KV+ +I K+
Sbjct: 273 VKEKVVTIIPKI 284
>gi|169165524 PREDICTED: similar to SVH protein isoform 2 [Homo
sapiens]
Length = 253
Score = 80.5 bits (197), Expect = 4e-15
Identities = 63/252 (25%), Positives = 113/252 (44%), Gaps = 56/252 (22%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNV 366
L ++ KL+ LL+ T+DP I E A + +G + A+ Q II ++G ++ N +N+ N
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 367 KEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFED 426
AL+ +++ S + E + YI QVC+ + S PLNS V L G
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVLLTG------------- 164
Query: 427 HYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNE 486
+ NT+ V SS ++ ++ +
Sbjct: 165 ------------------------------------NGNTK------VDSSFLSLYDSHV 182
Query: 487 SKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPE 546
+K +L ++ +F+NI K + L + FT+ L + ++ QK++ L +H D E
Sbjct: 183 AKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRALVDHHDAE 241
Query: 547 VRDKVIRLILKL 558
V++KV+ +I K+
Sbjct: 242 VKEKVVTIIPKI 253
>gi|113415138 PREDICTED: similar to SVH protein isoform 2 [Homo
sapiens]
Length = 253
Score = 78.6 bits (192), Expect = 1e-14
Identities = 62/252 (24%), Positives = 113/252 (44%), Gaps = 56/252 (22%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNV 366
L ++ KL+ LL+ T+DP I E A + +G + A+ Q II ++G ++ N +N+ N
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 367 KEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFED 426
AL+ +++ S + E + YI QVC+ + S PLNS V L G
Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVLLTG------------- 164
Query: 427 HYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNE 486
+ NT+ V SS ++ ++ +
Sbjct: 165 ------------------------------------NGNTK------VDSSFLSLYDSHV 182
Query: 487 SKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPE 546
+K +L ++ +F++I K + L + FT+ L + ++ QK++ L +H D E
Sbjct: 183 AKEILLRVLTLFQHIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRALVDHHDAE 241
Query: 547 VRDKVIRLILKL 558
V++KV+ +I K+
Sbjct: 242 VKEKVVTIIPKI 253
>gi|169165133 PREDICTED: similar to SVH protein isoform 1 [Homo
sapiens]
Length = 253
Score = 78.6 bits (192), Expect = 1e-14
Identities = 62/252 (24%), Positives = 113/252 (44%), Gaps = 56/252 (22%)
Query: 307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNV 366
L ++ KL+ LL+ T+DP I E A + +G + A+ Q II ++G ++ N +N+ N
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 367 KEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFED 426
AL+ +++ S + E + YI QVC+ + S PLNS V L G
Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVLLTG------------- 164
Query: 427 HYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNE 486
+ NT+ V SS ++ ++ +
Sbjct: 165 ------------------------------------NGNTK------VDSSFLSLYDSHV 182
Query: 487 SKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPE 546
+K +L ++ +F++I K + L + FT+ L + ++ QK++ L +H D E
Sbjct: 183 AKEILLRVLTLFQHIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRALVDHHDAE 241
Query: 547 VRDKVIRLILKL 558
V++KV+ +I K+
Sbjct: 242 VKEKVVTIIPKI 253
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,592,880
Number of Sequences: 37866
Number of extensions: 968465
Number of successful extensions: 3011
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 2690
Number of HSP's gapped (non-prelim): 173
length of query: 558
length of database: 18,247,518
effective HSP length: 107
effective length of query: 451
effective length of database: 14,195,856
effective search space: 6402331056
effective search space used: 6402331056
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.